{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:24:51Z","timestamp":1790738691215,"version":"4.1.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2019,11,9]],"date-time":"2019-11-09T00:00:00Z","timestamp":1573257600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,11,9]],"date-time":"2019-11-09T00:00:00Z","timestamp":1573257600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100003819","name":"Natural Science Foundation of Hubei Province","doi-asserted-by":"publisher","award":["2018CFB612"],"award-info":[{"award-number":["2018CFB612"]}],"id":[{"id":"10.13039\/501100003819","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biol Trace Elem Res"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1007\/s12011-019-01935-9","type":"journal-article","created":{"date-parts":[[2019,11,9]],"date-time":"2019-11-09T06:03:20Z","timestamp":1573279400000},"page":"512-516","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Comparison of Bioavailability, Pharmacokinetics, and Biotransformation of Selenium-Enriched Yeast and Sodium Selenite in Rats Using Plasma Selenium and Selenomethionine"],"prefix":"10.1007","volume":"196","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4630-1269","authenticated-orcid":false,"given":"Shuang-Qing","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,11,9]]},"reference":[{"issue":"2","key":"1935_CR1","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1248\/jhs.51.107","volume":"51","author":"KT Suzuki","year":"2005","unstructured":"Suzuki KT (2005) Metabolomics of selenium: Se metabolites based on speciation studies. J Health Sci 51(2):107\u2013114","journal-title":"J Health Sci"},{"issue":"1","key":"1935_CR2","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1039\/c3mt00185g","volume":"6","author":"M Roman","year":"2014","unstructured":"Roman M, Jitaru P, Barbante C (2014) Selenium biochemistry and its role for human health. Metallomics 6(1):25\u201354. \nhttps:\/\/doi.org\/10.1039\/c3mt00185g","journal-title":"Metallomics"},{"issue":"1-4","key":"1935_CR3","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1002\/biof.5520140120","volume":"14","author":"GF Combs Jr","year":"2001","unstructured":"Combs GF Jr, Clark LC, Turnbull BW (2001) An analysis of cancer prevention by selenium. Biofactors 14(1-4):153\u2013159","journal-title":"Biofactors"},{"issue":"22","key":"1935_CR4","doi-asserted-by":"publisher","first-page":"6635","DOI":"10.1021\/ac049280h","volume":"76","author":"JR Encinar","year":"2004","unstructured":"Encinar JR, Schaumloffel D, Ogra Y, Lobinski R (2004) Determination of selenomethionine and selenocysteine in human serum using speciated isotope dilution-capillary HPLC-inductively coupled plasma collision cell mass spectrometry. Anal Chem 76(22):6635\u20136642. \nhttps:\/\/doi.org\/10.1021\/ac049280h","journal-title":"Anal Chem"},{"key":"1935_CR5","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1039\/b717448a","volume":"23","author":"K Bier","year":"2008","unstructured":"Bier K, Vacchina V, Szpunar J, Bertinc G, Lobinnski R (2008) Simultaneous derivatization of selenocysteine and selenomethionine in animal blood prior to their specific determination by 2D size-exclusion ion-pairing reversed-phase HPLC-ICP MS. J Anal At Spectrom 23:508\u2013513","journal-title":"J Anal At Spectrom"},{"key":"1935_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.foodchem.2017.08.068","volume":"241","author":"SQ Zhang","year":"2018","unstructured":"Zhang SQ, Zhang HB, Zhang Y (2018) Quantification of selenomethionine in plasma using UPLC-MS\/MS after the oral administration of selenium-enriched yeast to rats. Food Chem 241:1\u20136. \nhttps:\/\/doi.org\/10.1016\/j.foodchem.2017.08.068","journal-title":"Food Chem"},{"issue":"10","key":"1935_CR7","doi-asserted-by":"publisher","first-page":"945","DOI":"10.1016\/j.jnutbio.2010.08.006","volume":"22","author":"CS Hoefig","year":"2011","unstructured":"Hoefig CS, Renko K, Kohrle J, Birringer M, Schomburg L (2011) Comparison of different selenocompounds with respect to nutritional value vs. toxicity using liver cells in culture. J Nutr Biochem 22(10):945\u2013955. \nhttps:\/\/doi.org\/10.1016\/j.jnutbio.2010.08.006","journal-title":"J Nutr Biochem"},{"issue":"2","key":"1935_CR8","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1017\/S0007114508922522","volume":"100","author":"MP Rayman","year":"2008","unstructured":"Rayman MP, Infante HG, Sargent M (2008) Food-chain selenium and human health: spotlight on speciation. Br J Nutr 100(2):238\u2013253. \nhttps:\/\/doi.org\/10.1017\/S0007114508922522","journal-title":"Br J Nutr"},{"issue":"7","key":"1935_CR9","doi-asserted-by":"publisher","first-page":"766","DOI":"10.2903\/j.efsa.2008.766","volume":"6","author":"European Food Safety Authority","year":"2008","unstructured":"European Food Safety Authority (2008) Selenium-enriched yeast as source for selenium added for nutritional purposes in foods for particular nutritional uses and foods (including food supplements) for the general population - scientific opinion of the panel on food additives, flavourings, processing aids and materials in contact with food. EFSA J 6(7):766. \nhttps:\/\/doi.org\/10.2903\/j.efsa.2008.766","journal-title":"EFSA J"},{"issue":"1","key":"1935_CR10","doi-asserted-by":"publisher","first-page":"119","DOI":"10.3177\/jnsv.45.119","volume":"45","author":"M Yoshida","year":"1999","unstructured":"Yoshida M, Fukunaga K, Tsuchita H, Yasumoto K (1999) An evaluation of the bioavailability of selenium in high-selenium yeast. J Nutr Sci Vitaminol (Tokyo) 45(1):119\u2013128","journal-title":"J Nutr Sci Vitaminol (Tokyo)"},{"issue":"3","key":"1935_CR11","doi-asserted-by":"publisher","first-page":"506","DOI":"10.3390\/ijms18030506","volume":"18","author":"K Takahashi","year":"2017","unstructured":"Takahashi K, Suzuki N, Ogra Y (2017) Bioavailability comparison of nine bioselenocompounds in vitro and in vivo. Int J Mol Sci 18(3):506. \nhttps:\/\/doi.org\/10.3390\/ijms18030506","journal-title":"Int J Mol Sci"},{"issue":"2","key":"1935_CR12","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1007\/BF02784266","volume":"65","author":"G Bogye","year":"1998","unstructured":"Bogye G, Alfthan G, Machay T (1998) Bioavailability of enteral yeast-selenium in preterm infants. Biol Trace Elem Res 65(2):143\u2013151","journal-title":"Biol Trace Elem Res"},{"key":"1935_CR13","doi-asserted-by":"publisher","first-page":"975820","DOI":"10.1155\/2014\/975820","volume":"2014","author":"X Liu","year":"2014","unstructured":"Liu X, Piao J, Huang Z, Zhang SQ, Li W, Tian Y, Yang X (2014) Determination of 16 selected trace elements in children plasma from china economical developed rural areas using high resolution magnetic sector inductively coupled mass spectrometry. J Anal Methods Chem 2014:975820. \nhttps:\/\/doi.org\/10.1155\/2014\/975820","journal-title":"J Anal Methods Chem"},{"issue":"10","key":"1935_CR14","doi-asserted-by":"publisher","first-page":"974","DOI":"10.1080\/02652030210153578","volume":"19","author":"KT Suzuki","year":"2002","unstructured":"Suzuki KT, Ogra Y (2002) Metabolic pathway for selenium in the body: speciation by HPLC-ICP MS with enriched Se. Food Addit Contam 19(10):974\u2013983. \nhttps:\/\/doi.org\/10.1080\/02652030210153578","journal-title":"Food Addit Contam"},{"issue":"1","key":"1935_CR15","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.cdp.2003.11.002","volume":"28","author":"DW Nyman","year":"2004","unstructured":"Nyman DW, Suzanne Stratton M, Kopplin MJ, Dalkin BL, Nagle RB, Jay Gandolfi A (2004) Selenium and selenomethionine levels in prostate cancer patients. Cancer Detect Prev 28(1):8\u201316. \nhttps:\/\/doi.org\/10.1016\/j.cdp.2003.11.002","journal-title":"Cancer Detect Prev"},{"issue":"7","key":"1935_CR16","doi-asserted-by":"publisher","first-page":"1304","DOI":"10.1007\/s00216-006-0529-8","volume":"385","author":"E Dumont","year":"2006","unstructured":"Dumont E, Vanhaecke F, Cornelis R (2006) Selenium speciation from food source to metabolites: a critical review. Anal Bioanal Chem 385(7):1304\u20131323. \nhttps:\/\/doi.org\/10.1007\/s00216-006-0529-8","journal-title":"Anal Bioanal Chem"},{"issue":"1-2","key":"1935_CR17","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.chroma.2006.01.088","volume":"1110","author":"LH Reyes","year":"2006","unstructured":"Reyes LH, Encinar JR, Marchante-Gayon JM, Alonso JI, Sanz-Medel A (2006) Selenium bioaccessibility assessment in selenized yeast after \u201cin vitro\u201d gastrointestinal digestion using two-dimensional chromatography and mass spectrometry. J Chromatogr A 1110(1-2):108\u2013116. \nhttps:\/\/doi.org\/10.1016\/j.chroma.2006.01.088","journal-title":"J Chromatogr A"}],"container-title":["Biological Trace Element Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12011-019-01935-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12011-019-01935-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12011-019-01935-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,8]],"date-time":"2020-11-08T01:12:15Z","timestamp":1604797935000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12011-019-01935-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,9]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["1935"],"URL":"https:\/\/doi.org\/10.1007\/s12011-019-01935-9","relation":{},"ISSN":["0163-4984","1559-0720"],"issn-type":[{"value":"0163-4984","type":"print"},{"value":"1559-0720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,9]]},"assertion":[{"value":"12 August 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 October 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 November 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"Animal experiments were adhered to the Guide for the Care and Use of Laboratory Animals (NIH publication no. 85-23, eighth edition in 2011) and were approved by our Institutional Animal Care and Use Committee.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}