{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T19:49:15Z","timestamp":1770061755649,"version":"3.49.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2020,8,21]],"date-time":"2020-08-21T00:00:00Z","timestamp":1597968000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,8,21]],"date-time":"2020-08-21T00:00:00Z","timestamp":1597968000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100000063","name":"Office of Dietary Supplements","doi-asserted-by":"publisher","award":["HHSN2752011000011"],"award-info":[{"award-number":["HHSN2752011000011"]}],"id":[{"id":"10.13039\/100000063","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000063","name":"Office of Dietary Supplements","doi-asserted-by":"publisher","award":["HHSN27500009"],"award-info":[{"award-number":["HHSN27500009"]}],"id":[{"id":"10.13039\/100000063","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Finnish Medical Association of Clinical Chemistry"},{"name":"Intramural Research Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biol Trace Elem Res"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1007\/s12011-020-02341-2","type":"journal-article","created":{"date-parts":[[2020,8,21]],"date-time":"2020-08-21T15:03:21Z","timestamp":1598022201000},"page":"2131-2137","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["The Joint Role of Iodine Status and Thyroid Function on Risk for Preeclampsia in Finnish Women: a Population-Based Nested Case-Control Study"],"prefix":"10.1007","volume":"199","author":[{"given":"Elijah C.","family":"Reische","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tuija","family":"M\u00e4nnist\u00f6","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Purdue-Smithe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kurunthachalam","family":"Kannan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Un-Jung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eila","family":"Suvanto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helj\u00e4-Marja","family":"Surcel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mika","family":"Gissler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James L.","family":"Mills","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,8,21]]},"reference":[{"issue":"1","key":"2341_CR1","first-page":"e1","volume":"133","author":"The American College of Obstetricians and Gynecologists","year":"2019","unstructured":"The American College of Obstetricians and Gynecologists (2019) ACOG practice bulletin number 202: gestational hypertension and preeclampsia. Obstet Gynecol 133(1):e1\u2013e325","journal-title":"Obstet Gynecol"},{"issue":"4","key":"2341_CR2","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/j.bpobgyn.2011.01.006","volume":"25","author":"JA Hutcheon","year":"2011","unstructured":"Hutcheon JA, Lisonkova S, Joseph KS (2011) Epidemiology of pre-eclampsia and the other hypertensive disorders of pregnancy. Rev Best Pract Res Clin Obstet Gynaecol 25(4):391\u2013403. https:\/\/doi.org\/10.1016\/j.bpobgyn.2011.01.006","journal-title":"Rev Best Pract Res Clin Obstet Gynaecol"},{"key":"2341_CR3","doi-asserted-by":"publisher","first-page":"l2381","DOI":"10.1136\/bmj.l2381","volume":"366","author":"GJ Burton","year":"2019","unstructured":"Burton GJ, Redman CW, Roberts JM, Moffett A (2019) Pre-eclampsia: pathophysiology and clinical implications. BMJ 366:l2381. https:\/\/doi.org\/10.1136\/bmj.l2381","journal-title":"BMJ"},{"key":"2341_CR4","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1146\/annurev-pathol-121808-102149","volume":"5","author":"BC Young","year":"2010","unstructured":"Young BC, Levine RJ, Karumanchi SA (2010) Pathogenesis of preeclampsia. Rev Annu Rev Pathol 5:173\u2013192. https:\/\/doi.org\/10.1146\/annurev-pathol-121808-102149","journal-title":"Rev Annu Rev Pathol"},{"issue":"3","key":"2341_CR5","doi-asserted-by":"publisher","first-page":"661","DOI":"10.20960\/nh.460","volume":"34","author":"S Cuellar-Rufino","year":"2017","unstructured":"Cuellar-Rufino S, Navarro-Meza M, Garc\u00eda-Sol\u00eds P, Xochihua-Rosas I, Arroyo-Helguera O (2017) Iodine levels are associated with oxidative stress and antioxidant status in pregnant women with hypertensive disease. Nutr Hosp 34(3):661\u2013666. https:\/\/doi.org\/10.20960\/nh.460","journal-title":"Nutr Hosp"},{"issue":"8","key":"2341_CR6","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1089\/thy.2012.0579","volume":"23","author":"C Aceves","year":"2013","unstructured":"Aceves C, Anguiano B, Delgado G (2013) The extrathyronine actions of iodine as antioxidant, apoptotic, and differentiation factor in various tissues. Rev Thyroid 23(8):938\u2013946. https:\/\/doi.org\/10.1089\/thy.2012.0579","journal-title":"Rev Thyroid"},{"issue":"3","key":"2341_CR7","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1007\/s12011-009-8539-y","volume":"136","author":"M Gulaboglu","year":"2010","unstructured":"Gulaboglu M, Borekci B, Delibas I (2010) Urine iodine levels in preeclamptic and normal pregnant women. Biol Trace Elem Res 136(3):249\u2013257. https:\/\/doi.org\/10.1007\/s12011-009-8539-y","journal-title":"Biol Trace Elem Res"},{"issue":"1-3","key":"2341_CR8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s12011-008-8278-5","volume":"129","author":"B Borekci","year":"2009","unstructured":"Borekci B, Gulaboglu M, Gul M (2009) Iodine and magnesium levels in maternal and umbilical cord blood of preeclamptic and normal pregnant women. Biol Trace Elem Res 129(1-3):1\u20138. https:\/\/doi.org\/10.1007\/s12011-008-8278-5","journal-title":"Biol Trace Elem Res"},{"issue":"2","key":"2341_CR9","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1016\/j.ijgo.2007.03.047","volume":"98","author":"M Gulaboglu","year":"2007","unstructured":"Gulaboglu M, Borekci B, Halici Z (2007) Placental tissue iodine level and blood magnesium concentration in pre-eclamptic and normal pregnancy. Int J Gynaecol Obstet 98(2):100\u2013104. https:\/\/doi.org\/10.1016\/j.ijgo.2007.03.047","journal-title":"Int J Gynaecol Obstet"},{"key":"2341_CR10","doi-asserted-by":"publisher","unstructured":"Nazarpour S, Tehrani FR, Behboudi-Gandevani S, Yarandi RB, Azizi F (2019) Maternal urinary iodine concentration and pregnancy outcomes in euthyroid pregnant women: a systematic review and meta-analysis. Rev Biol Trace Elem Res Dec 24 [Online ahead of print]. https:\/\/doi.org\/10.1007\/s12011-019-02020-x","DOI":"10.1007\/s12011-019-02020-x"},{"issue":"3","key":"2341_CR11","doi-asserted-by":"publisher","first-page":"291","DOI":"10.3390\/nu10030291","volume":"10","author":"B Torlinska","year":"2018","unstructured":"Torlinska B, Bath SC, Janjua A, Boelaert K, Chan S-Y (2018) Iodine status during pregnancy in a region of mild-to-moderate iodine deficiency is not associated with adverse obstetric outcomes; results from the Avon longitudinal study of parents and children (ALSPAC). Nutrients 10(3):291. https:\/\/doi.org\/10.3390\/nu10030291","journal-title":"Nutrients"},{"key":"2341_CR12","unstructured":"Iodine Global Network (2017) Global scorecard of iodine nutrition in 2017 in the general population and in pregnant women (PW). Available online: https:\/\/www.ign.org\/cm_data\/IGN_Global_Scorecard_AllPop_and_PW_May2017.pdfAccessed November 7, 2019."},{"key":"2341_CR13","unstructured":"Helld\u00e1n A, Raulio S, Kosola M, Tapanainen H, Ovaskainen M-L, Virtanen S (2013) The national FINDIET 2012 survey. National Institute for Health and Welfare. https:\/\/www.julkari.fi\/handle\/10024\/110839"},{"issue":"11","key":"2341_CR14","doi-asserted-by":"publisher","first-page":"2573","DOI":"10.3390\/nu11112573","volume":"11","author":"AC Purdue-Smithe","year":"2019","unstructured":"Purdue-Smithe AC, M\u00e4nnist\u00f6 T, Bell GA, Mumford SL, Liu A, Kannan K, Kim U-J, Suvanto E, Surcel H-M, Gissler M, Mills J (2019) The joint role of thyroid function and iodine status on risk of preterm birth and small for gestational age: a population-based nested case-control study of Finnish women. Nutrients 11(11):2573. https:\/\/doi.org\/10.3390\/nu11112573","journal-title":"Nutrients"},{"issue":"4","key":"2341_CR15","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1111\/aogs.13523","volume":"98","author":"GA Bell","year":"2019","unstructured":"Bell GA, M\u00e4nnist\u00f6 T, Liu A, Kannan K, Yeung EH, Kim U-J, Suvanto E, Surcel H-M, Gissler M, Mills JL (2019) The joint role of thyroid function and iodine concentration on gestational diabetes risk in a population-based study. Acta Obstet Gynecol Scand 98(4):500\u2013506. https:\/\/doi.org\/10.1111\/aogs.13523","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"7","key":"2341_CR16","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1111\/aogs.12882","volume":"95","author":"N Jaatinen","year":"2016","unstructured":"Jaatinen N, Ekholm E (2016) Eclampsia in Finland; 2006 to 2010. Acta Obstet Gynecol Scand 95(7):787\u2013792. https:\/\/doi.org\/10.1111\/aogs.12882","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"1","key":"2341_CR17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/BF03350244","volume":"14","author":"E Roti","year":"1991","unstructured":"Roti E, Gardini E, Minelli R, Bianconi L, Flisi M (1991) Thyroid function evaluation by different commercially available free thyroid hormone measurement kits in term pregnant women and their newborns. J Endocrinol Investig 14(1):1\u20139. https:\/\/doi.org\/10.1007\/BF03350244","journal-title":"J Endocrinol Investig"},{"issue":"3","key":"2341_CR18","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1089\/thy.2010.0337","volume":"21","author":"T M\u00e4nnist\u00f6","year":"2011","unstructured":"M\u00e4nnist\u00f6 T, Surcel H-M, Ruokonen A, V\u00e4\u00e4r\u00e4sm\u00e4ki M, Pouta A, Bloigu A, J\u00e4rvelin MR, Hartikainen A-L, Suvanto E (2011) Early pregnancy reference intervals of thyroid hormone concentrations in a thyroid antibody-negative pregnant population. Thyroid 21(3):291\u2013298. https:\/\/doi.org\/10.1089\/thy.2010.0337","journal-title":"Thyroid"},{"issue":"1","key":"2341_CR19","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1023\/A:1013224010632","volume":"249","author":"NK Aras","year":"2001","unstructured":"Aras NK, Nazli A, Zhang W, Chatt A (2001) Dietary intake of zinc and selenium in Turkey. J Radioanal Nucl Chem 249(1):33\u201337","journal-title":"J Radioanal Nucl Chem"},{"key":"2341_CR20","unstructured":"The World Bank (2011) Nutrition at a glance: Turkey. Available online: http:\/\/documents.worldbank.org\/curated\/en\/181101468172768168\/pdf\/772030BRI0Box00C00turkey0April02011.pdf. Accessed January 7, 2020"},{"issue":"4","key":"2341_CR21","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1097\/OGX.0000000000000547","volume":"73","author":"DR Shinohara","year":"2018","unstructured":"Shinohara DR, Santos TDS, de Carvalho HC, Lopes LCB, G\u00fcnther LSA, Aristides SMA, Teixeira JJV, Demarchi IG (2018) Pregnancy complications associated with maternal hypothyroidism: a systematic review. Obstet Gynecol Surv 73(4):219\u2013230. https:\/\/doi.org\/10.1097\/OGX.0000000000000547","journal-title":"Obstet Gynecol Surv"},{"issue":"7","key":"2341_CR22","first-page":"387","volume":"13","author":"S Nazarpour","year":"2015","unstructured":"Nazarpour S, Tehrani FR, Simbar M, Azizi F (2015) Thyroid dysfunction and pregnancy outcomes. Iran J Reprod Med 13(7):387\u2013396","journal-title":"Iran J Reprod Med"},{"issue":"6","key":"2341_CR23","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1080\/00365513.2018.1512150","volume":"78","author":"S Yu","year":"2018","unstructured":"Yu S, Yin Y, Cheng Q, Han J, Cheng X, Guo Y, Sun D, Xie S, Qiu L (2018) Validation of a simple inductively coupled plasma mass spectrometry method for detecting urine and serum iodine and evaluation of iodine status of pregnant women in Beijing. Scand J Clin Lab Invest 78(6):501\u2013507. https:\/\/doi.org\/10.1080\/00365513.2018.1512150","journal-title":"Scand J Clin Lab Invest"},{"issue":"6","key":"2341_CR24","doi-asserted-by":"publisher","first-page":"1012","DOI":"10.1093\/jn\/nxy325","volume":"149","author":"T Cui","year":"2019","unstructured":"Cui T, Wang W, Chen W, Pan Z, Gao S, Tan L, Pearce EN, Zimmermann MB, Shen J, Zhang W (2019) Serum iodine is correlated with iodine intake and thyroid function in school-age children from a sufficient-to-excessive iodine intake area. J Nutr 149(6):1012\u20131018. https:\/\/doi.org\/10.1093\/jn\/nxy325","journal-title":"J Nutr"},{"issue":"1 & 2","key":"2341_CR25","first-page":"67","volume":"10","author":"GA Kandhro","year":"2009","unstructured":"Kandhro GA, Kazi TG, Sirjuddin KN, Afridi HI, Arain MB, Baig A, Shah AQ, Syed N (2009) Evaluation of the iodine concentration in serum and urine of hypothyroid males using an inexpensive and rapid method. Pak J Anal Environ Chem 10(1 & 2):67\u201375 ISSN 2221-5255","journal-title":"Pak J Anal Environ Chem"},{"issue":"5","key":"2341_CR26","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1038\/sj.ejcn.1600762","volume":"53","author":"LB Rasmussen","year":"1999","unstructured":"Rasmussen LB, Ovesen L, Christiansen E (1999) Day-to-day and within-day variation in urinary iodine excretion. Eur J Clin Nutr 53(5):401\u2013407. https:\/\/doi.org\/10.1038\/sj.ejcn.1600762","journal-title":"Eur J Clin Nutr"}],"container-title":["Biological Trace Element Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12011-020-02341-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12011-020-02341-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12011-020-02341-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,21]],"date-time":"2021-08-21T00:30:37Z","timestamp":1629505837000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12011-020-02341-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,21]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["2341"],"URL":"https:\/\/doi.org\/10.1007\/s12011-020-02341-2","relation":{},"ISSN":["0163-4984","1559-0720"],"issn-type":[{"value":"0163-4984","type":"print"},{"value":"1559-0720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,21]]},"assertion":[{"value":"21 May 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 August 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 August 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of Interest"}},{"value":"This study was approved by the steering committee of the FMC; the ethical review boards of the Northern Ostrobothnia Hospital District and the Finnish Institute for Health and Welfare, Oulu, Finland; and the Office of Human Subjects Research, National Institutes of Health, Bethesda, MD, USA (#13459).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"Participants gave written informed consent for their samples to be used for research purposes.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}}]}}