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S., K. M., S. K., and K. A. are salaried employees of Meiji Co., Ltd. which also provided experimental materials, facilities, and staff assistance to K.S.. K. N. declares no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of Interest"}},{"value":"The protocol for all experiments involving animals was approved by the Meiji Corporation Ethics Committee for Animal Care and Use (Tokyo, Japan, Approval No. 2016_3871_0293 and 2017_3871_0023). 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