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However, as an organic zinc source, the application of zinc lactate (ZL) on Chinese yellow-feathered broilers has been rarely reported. Hence, the present study aimed to investigate the effects of ZL supplementation on growth performance, small intestinal morphology, serum biochemical parameters, immune organ index, as well as hepatic metallothionein of Chinese yellow-feathered broilers. A total of 2100 broilers (19\u00a0days old) were randomly assigned to 5 treatment groups, including the control (fed basal diet), ZL40 (basal diet plus 40\u00a0mg\/kg ZL), ZL60 (basal diet plus 60\u00a0mg\/kg ZL), ZL80 (basal diet plus 80\u00a0mg\/kg ZL), and ZS80 (basal diet plus 80\u00a0mg\/kg ZS. Each treatment group had 6 replicates with 70 chickens per replicate. Compared to the control group, the ZL40 and the ZS80 groups had a lower feed to gain ratio (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05), ZL40 group had higher duodenum and ileum villus heights (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05), and ZS80 and ZL80 groups had a lower ratio of villus height to crypt depth in the jejunum (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). In addition, the ZL60 group had a higher concentration of total protein (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05) and activity of glutathione peroxidase (GSH-Px) (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01) compared with the ZS80 and the control groups. Interestingly, the ZL40, ZL60, and ZL80 groups all had higher levels of hepatic metallothionein than the other groups (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). In conclusion, zinc lactate had a higher bioavailability and could be used as an alternative to zinc sulfate.<\/jats:p>","DOI":"10.1007\/s12011-021-02785-0","type":"journal-article","created":{"date-parts":[[2021,6,17]],"date-time":"2021-06-17T23:25:25Z","timestamp":1623972325000},"page":"1835-1843","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Effects of Zinc Lactate Supplementation on Growth Performance, Intestinal Morphology, Serum Parameters, and Hepatic Metallothionein of Chinese Yellow-Feathered Broilers"],"prefix":"10.1007","volume":"200","author":[{"given":"Lina","family":"Long","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1392-917X","authenticated-orcid":false,"given":"Xichen","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haojie","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huihua","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,6,17]]},"reference":[{"issue":"4","key":"2785_CR1","doi-asserted-by":"publisher","first-page":"881","DOI":"10.3382\/japr.2012-00531","volume":"21","author":"MK Manangi","year":"2012","unstructured":"Manangi MK, Vazquez-A\u00f1on M, Richards JD, Carter S, Buresh RE, Christensen KD (2012) Impact of feeding lower levels of chelated trace minerals versus industry levels of inorganic trace minerals on broiler performance, yield, footpad health, and litter mineral concentration. 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