{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T10:07:34Z","timestamp":1791540454186,"version":"4.3.4"},"reference-count":72,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T00:00:00Z","timestamp":1629417600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T00:00:00Z","timestamp":1629417600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100004256","name":"razi university","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004256","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biol Trace Elem Res"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1007\/s12011-021-02885-x","type":"journal-article","created":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T21:03:20Z","timestamp":1629493400000},"page":"2876-2888","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Chromium Supplementation on the Growth Performance, Carcass Traits, Blood Constituents, and Immune Competence of Broiler Chickens Under Heat Stress: a Systematic Review and Dose\u2013Response Meta-analysis"],"prefix":"10.1007","volume":"200","author":[{"given":"Alihossein","family":"Piray","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saheb","family":"Foroutanifar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,8,20]]},"reference":[{"key":"2885_CR1","unstructured":"FAO (2020) Meat market review: emerging trends and outlook, December 2020. FAO"},{"key":"2885_CR2","doi-asserted-by":"publisher","unstructured":"Vandana G, Sejian V, Lees A, Pragna P, Silpa M, Maloney SK (2020) Heat stress and poultry production: impact and amelioration. Int J Biometeorol:1\u201317. https:\/\/doi.org\/10.1007\/s00484-020-02023-7","DOI":"10.1007\/s00484-020-02023-7"},{"key":"2885_CR3","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1016\/j.jtherbio.2019.07.025","volume":"84","author":"M Saeed","year":"2019","unstructured":"Saeed M, Abbas G, Alagawany M, Kamboh AA, Abd El-Hack ME, Khafaga AF, Chao S (2019) Heat stress management in poultry farms: a comprehensive overview. J Therm Biol 84:414\u2013425. https:\/\/doi.org\/10.1016\/j.jtherbio.2019.07.025","journal-title":"J Therm Biol"},{"key":"2885_CR4","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1080\/00071660500190918","volume":"46","author":"N Sahin","year":"2005","unstructured":"Sahin N, Sahin K, Onderci M, Gursu M, Cikim G, Vijaya J, Kucuk O (2005) Chromium picolinate, rather than biotin, alleviates performance and metabolic parameters in heat-stressed quail. Br Poult Sci 46:457\u2013463. https:\/\/doi.org\/10.1080\/00071660500190918","journal-title":"Br Poult Sci"},{"key":"2885_CR5","doi-asserted-by":"publisher","first-page":"1266","DOI":"10.3390\/ani10081266","volume":"10","author":"S Wasti","year":"2020","unstructured":"Wasti S, Sah N, Mishra B (2020) Impact of heat stress on poultry health and performances, and potential mitigation strategies. Animals 10:1266. https:\/\/doi.org\/10.3390\/ani10081266","journal-title":"Animals"},{"key":"2885_CR6","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1007\/s12011-018-1575-8","volume":"188","author":"PE White","year":"2019","unstructured":"White PE, Vincent JB (2019) Systematic review of the effects of chromium (III) on chickens. Biol Trace Elem Res 188:99\u2013126. https:\/\/doi.org\/10.1007\/s12011-018-1575-8","journal-title":"Biol Trace Elem Res"},{"key":"2885_CR7","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1590\/1678-5150-PVB-6355","volume":"40","author":"IK Sousa","year":"2020","unstructured":"Sousa IK, Sousa RS, Mori CS, Morini AC, Neves KA, Minervino AH, Ortolani EL (2020) Influence of organic chromium supplementation on the performance of beef calves undergoing weaning-related stress. Pesq Vet Bras 40:97\u2013101. https:\/\/doi.org\/10.1590\/1678-5150-PVB-6355","journal-title":"Pesq Vet Bras"},{"key":"2885_CR8","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/S0271-5317(02)00513-4","volume":"23","author":"K Sahin","year":"2003","unstructured":"Sahin K, Sahin N, Kucuk O (2003) Effects of chromium, and ascorbic acid supplementation on growth, carcass traits, serum metabolites, and antioxidant status of broiler chickens reared at a high ambient temperature (32 C). Nutr Res 23:225\u2013238. https:\/\/doi.org\/10.1016\/S0271-5317(02)00513-4","journal-title":"Nutr Res"},{"key":"2885_CR9","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1007\/s12011-011-9116-8","volume":"144","author":"MM Moeini","year":"2011","unstructured":"Moeini MM, Bahrami A, Ghazi S, Targhibi MR (2011) The effect of different levels of organic and inorganic chromium supplementation on production performance, carcass traits and some blood parameters of broiler chicken under heat stress condition. Biol Trace Elem Res 144:715\u2013724. https:\/\/doi.org\/10.1007\/s12011-011-9116-8","journal-title":"Biol Trace Elem Res"},{"key":"2885_CR10","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1007\/s12011-013-9663-2","volume":"153","author":"M Habibian","year":"2013","unstructured":"Habibian M, Ghazi S, Moeini MM (2013) Lack of effect of dietary chromium supplementation on growth performance and serum insulin, glucose, and lipoprotein levels in broilers reared under heat stress condition. Biol Trace Elem Res 153:205\u2013211. https:\/\/doi.org\/10.1007\/s12011-013-9663-2","journal-title":"Biol Trace Elem Res"},{"key":"2885_CR11","doi-asserted-by":"publisher","first-page":"3355","DOI":"10.2527\/jas.2014-8807","volume":"93","author":"R Jahanian","year":"2015","unstructured":"Jahanian R, Rasouli E (2015) Dietary chromium methionine supplementation could alleviate immunosuppressive effects of heat stress in broiler chicks. J Anim Sci 93:3355\u20133363. https:\/\/doi.org\/10.2527\/jas.2014-8807","journal-title":"J Anim Sci"},{"key":"2885_CR12","doi-asserted-by":"publisher","unstructured":"Piray AH, Foroutanifar S (2021) Effect of chromium supplementation on performance, carcass characteristics, blood biochemistry, and immune response of unstressed broiler chickens: a dose-response meta-analysis. Biol Trace\u00a0Elem Res:1\u20138. https:\/\/doi.org\/10.1007\/s12011-021-02589-2","DOI":"10.1007\/s12011-021-02589-2"},{"key":"2885_CR13","doi-asserted-by":"publisher","first-page":"1579","DOI":"10.1177\/0962280218773122","volume":"28","author":"A Crippa","year":"2019","unstructured":"Crippa A, Discacciati A, Bottai M, Spiegelman D, Orsini N (2019) One-stage dose\u2013response meta-analysis for aggregated data. Stat Methods Med Res 28:1579\u20131596. https:\/\/doi.org\/10.1177\/0962280218773122","journal-title":"Stat Methods Med Res"},{"key":"2885_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12877-018-0904-2","volume":"18","author":"SY Ju","year":"2018","unstructured":"Ju SY, Lee JY, Kim DH (2018) Low 25-hydroxyvitamin D levels and the risk of frailty syndrome: a systematic review and dose-response meta-analysis. BMC Geriatr 18:1\u201311. https:\/\/doi.org\/10.1186\/s12877-018-0904-2","journal-title":"BMC Geriatr"},{"key":"2885_CR15","doi-asserted-by":"publisher","unstructured":"Dmitrienko A, Lipkovich I, Dane A, Muysers C (2020) Data-driven and confirmatory subgroup analysis in clinical trials. In: Design and Analysis of Subgroups with Biopharmaceutical Applications. Springer, pp 33\u201391. https:\/\/doi.org\/10.1007\/978-3-030-40105-4","DOI":"10.1007\/978-3-030-40105-4"},{"key":"2885_CR16","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1007\/s10654-017-0246-y","volume":"32","author":"L Schwingshackl","year":"2017","unstructured":"Schwingshackl L, Hoffmann G, Lampousi A-M, Kn\u00fcppel S, Iqbal K, Schwedhelm C, Bechthold A, Schlesinger S, Boeing H (2017) Food groups and risk of type 2 diabetes mellitus: a systematic review and meta-analysis of prospective studies. Eur J Epidemiol 32:363\u2013375. https:\/\/doi.org\/10.1007\/s10654-017-0246-y","journal-title":"Eur J Epidemiol"},{"key":"2885_CR17","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1385\/BTER:89:1:53","volume":"89","author":"K Sahin","year":"2002","unstructured":"Sahin K, Sahin N, Onderci M, Gursu F, Cikim G (2002) Optimal dietary concentration of chromium for alleviating the effect of heat stress on growth, carcass qualities, and some serum metabolites of broiler chickens. Biol Trace Elem Res 89:53\u201364. https:\/\/doi.org\/10.1385\/BTER:89:1:53","journal-title":"Biol Trace Elem Res"},{"key":"2885_CR18","doi-asserted-by":"publisher","first-page":"65","DOI":"10.3923\/IJPS.2006.65.69","volume":"5","author":"M Toghyani","year":"2006","unstructured":"Toghyani M, Shivazad M, Gheisari A, Zarkesh S (2006) Performance, carcass traits and hematological parameters of heat-stressed broiler chicks in response to dietary levels of chromium picolinate. Int J Poult Sci 5:65\u201369. https:\/\/doi.org\/10.3923\/IJPS.2006.65.69","journal-title":"Int J Poult Sci"},{"key":"2885_CR19","doi-asserted-by":"publisher","first-page":"330","DOI":"10.2141\/jpsa.44.330","volume":"44","author":"M Toghyani","year":"2007","unstructured":"Toghyani M, Zarkesh S, Shivazad M, Gheisari A (2007) Immune responses of broiler chicks fed chromium picolinate in heat stress condition. J Poult Sci 44:330\u2013334. https:\/\/doi.org\/10.2141\/jpsa.44.330","journal-title":"J Poult Sci"},{"key":"2885_CR20","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1002\/jsfa.3146","volume":"88","author":"S Samanta","year":"2008","unstructured":"Samanta S, Haldar S, Bahadur V, Ghosh TK (2008) Chromium picolinate can ameliorate the negative effects of heat stress and enhance performance, carcass and meat traits in broiler chickens by reducing the circulatory cortisol level. J Sci Food Agric 88:787\u2013796. https:\/\/doi.org\/10.1002\/jsfa.3146","journal-title":"J Sci Food Agric"},{"key":"2885_CR21","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1080\/00071660801946950","volume":"49","author":"S Samanta","year":"2008","unstructured":"Samanta S, Haldar S, Ghosh T (2008) Production and carcase traits in broiler chickens given diets supplemented with inorganic trivalent chromium and an organic acid blend. Br Poult Sci 49:155\u2013163. https:\/\/doi.org\/10.1080\/00071660801946950","journal-title":"Br Poult Sci"},{"key":"2885_CR22","doi-asserted-by":"publisher","first-page":"1782","DOI":"10.1002\/jsfa.3656","volume":"89","author":"LY Zha","year":"2009","unstructured":"Zha LY, Zeng JW, Chu XW, Mao LM, Luo HJ (2009) Efficacy of trivalent chromium on growth performance, carcass characteristics and tissue chromium in heat-stressed broiler chicks. J Sci Food Agric 89:1782\u20131786. https:\/\/doi.org\/10.1002\/jsfa.3656","journal-title":"J Sci Food Agric"},{"key":"2885_CR23","doi-asserted-by":"publisher","first-page":"209","DOI":"10.3382\/japr.2010-00275","volume":"21","author":"A Bahrami","year":"2012","unstructured":"Bahrami A, Moeini M, Ghazi S, Targhibi M (2012) The effect of different levels of organic and inorganic chromium supplementation on immune function of broiler chicken under heat-stress conditions. J Appl Poult Res 21:209\u2013215. https:\/\/doi.org\/10.3382\/japr.2010-00275","journal-title":"J Appl Poult Res"},{"key":"2885_CR24","doi-asserted-by":"publisher","first-page":"256","DOI":"10.5713\/ajas.2011.11217","volume":"25","author":"S Ebrahimzadeh","year":"2012","unstructured":"Ebrahimzadeh S, Farhoomand P, Noori K (2012) Immune response of broiler chickens fed diets supplemented with different level of chromium methionine under heat stress conditions. Asian-australas J Anim Sci 25:256. https:\/\/doi.org\/10.5713\/ajas.2011.11217","journal-title":"Asian-australas J Anim Sci"},{"key":"2885_CR25","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1007\/s12011-011-9260-1","volume":"146","author":"S Ghazi","year":"2012","unstructured":"Ghazi S, Habibian M, Moeini M, Abdolmohammadi A (2012) Effects of different levels of organic and inorganic chromium on growth performance and immunocompetence of broilers under heat stress. Biol Trace Elem Res 146:309\u2013317. https:\/\/doi.org\/10.1007\/s12011-011-9260-1","journal-title":"Biol Trace Elem Res"},{"key":"2885_CR26","first-page":"79","volume":"2","author":"K Noori","year":"2012","unstructured":"Noori K, Farhoomand P, Ebrahimzadeh S (2012) Effect of chromium methionine supplementation on performance and serum metabolites in broiler chickens thermoneutral and under heat-stress conditions. Iran J Appl Anim Sci 2:79\u201382","journal-title":"Iran J Appl Anim Sci"},{"key":"2885_CR27","doi-asserted-by":"publisher","first-page":"48","DOI":"10.5539\/jas.v4n12p48","volume":"4","author":"N Sirirat","year":"2012","unstructured":"Sirirat N, Lu J-J, Hung AT-Y, Chen S-Y, Lien T-F (2012) Effects different levels of nanoparticles chromium picolinate supplementation on growth performance, mineral retention, and immune responses in broiler chickens. J Agric Sci 4:48. https:\/\/doi.org\/10.5539\/jas.v4n12p48","journal-title":"J Agric Sci"},{"key":"2885_CR28","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1007\/s12011-011-9234-3","volume":"146","author":"M Toghyani","year":"2012","unstructured":"Toghyani M, Toghyani M, Shivazad M, Gheisari A, Bahadoran R (2012) Chromium supplementation can alleviate the negative effects of heat stress on growth performance, carcass traits, and meat lipid oxidation of broiler chicks without any adverse impacts on blood constituents. Biol Trace Elem Res 146:171\u2013180. https:\/\/doi.org\/10.1007\/s12011-011-9234-3","journal-title":"Biol Trace Elem Res"},{"key":"2885_CR29","doi-asserted-by":"publisher","first-page":"1383","DOI":"10.1007\/s00484-013-0740-1","volume":"58","author":"M Akbari","year":"2014","unstructured":"Akbari M, Torki M (2014) Effects of dietary chromium picolinate and peppermint essential oil on growth performance and blood biochemical parameters of broiler chicks reared under heat stress conditions. Int J Biometeorol 58:1383\u20131391. https:\/\/doi.org\/10.1007\/s00484-013-0740-1","journal-title":"Int J Biometeorol"},{"key":"2885_CR30","doi-asserted-by":"publisher","first-page":"382","DOI":"10.3382\/japr.2011-00506","volume":"22","author":"S Ebrahimzadeh","year":"2013","unstructured":"Ebrahimzadeh S, Farhoomand P, Noori K (2013) Effects of chromium methionine supplementation on performance, carcass traits, and the Ca and P metabolism of broiler chickens under heat-stress conditions. J Appl Poult Res 22:382\u2013387. https:\/\/doi.org\/10.3382\/japr.2011-00506","journal-title":"J Appl Poult Res"},{"key":"2885_CR31","first-page":"e92","volume":"12","author":"TM Norain","year":"2013","unstructured":"Norain TM, Ismail IB, Abdoun KA, Al-Haidary AA (2013) Dietary inclusion of chromium to improve growth performance and immune-competence of broilers under heat stress. Ital J Anim Sci 12:e92","journal-title":"Ital J Anim Sci"},{"key":"2885_CR32","first-page":"10","volume":"4","author":"SS Tawfeek","year":"2014","unstructured":"Tawfeek SS, Hassanin K, Youssef IMI (2014) The effect of dietary supplementation of some antioxidants on performance, oxidative stress, and blood parameters in broilers under natural summer conditions. J World\u2019s Poult Res 4:10\u201319","journal-title":"J World's Poult Res"},{"key":"2885_CR33","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1111\/jpn.12215","volume":"99","author":"Y Lin","year":"2015","unstructured":"Lin Y, Huang J, Li M, Cheng C, Lien T (2015) Effects of supplemental nanoparticle trivalent chromium on the nutrient utilization, growth performance and serum traits of broilers. J Anim Physiol Anim Nutr 99:59\u201365. https:\/\/doi.org\/10.1111\/jpn.12215","journal-title":"J Anim Physiol Anim Nutr"},{"key":"2885_CR34","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1007\/s12011-015-0443-z","volume":"170","author":"Y Huang","year":"2016","unstructured":"Huang Y, Yang J, Xiao F, Lloyd K, Lin X (2016) Effects of supplemental chromium source and concentration on growth performance, carcass traits, and meat quality of broilers under heat stress conditions. Biol Trace Elem Res 170:216\u2013223. https:\/\/doi.org\/10.1007\/s12011-015-0443-z","journal-title":"Biol Trace Elem Res"},{"key":"2885_CR35","unstructured":"Hajializadeh F, Ghahri H, Talebi A Effects of supplemental chromium picolinate and chromium nanoparticles on performance and antibody titers of infectious bronchitis and avian influenza of broiler chickens under heat stress condition. In: Vet Res Forum, 2017. vol 3. Faculty of Veterinary Medicine, Urmia University, Urmia, Iran, p 259"},{"key":"2885_CR36","doi-asserted-by":"publisher","unstructured":"Hamidi O, Chamani M, Ghahri H, Sadeghi A, Malekinejad H (2017) effects of chromium iii picolinate and chromium iii picolinate nanoparticles supplementation on growth performance organs weight and immune function in cyclic heat stressed broiler chickens. Arch\u00a0Vet Sci Tech AVST-113. https:\/\/doi.org\/10.29011\/2637-9988\/100013","DOI":"10.29011\/2637-9988\/100013"},{"key":"2885_CR37","doi-asserted-by":"publisher","first-page":"4317","DOI":"10.3382\/ps\/pex249","volume":"96","author":"N Sahin","year":"2017","unstructured":"Sahin N, Hayirli A, Orhan C, Tuzcu M, Akdemir F, Komorowski J, Sahin K (2017) Effects of the supplemental chromium form on performance and oxidative stress in broilers exposed to heat stress. Poult Sci 96:4317\u20134324. https:\/\/doi.org\/10.3382\/ps\/pex249","journal-title":"Poult Sci"},{"key":"2885_CR38","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1007\/s12011-016-0852-7","volume":"176","author":"F Xiao","year":"2017","unstructured":"Xiao F, Ao D, Zhou B, Spears JW, Lin X, Huang Y (2017) Effects of supplemental chromium propionate on serum lipids, carcass traits, and meat quality of heat-stressed broilers. Biol Trace Elem Res 176:401\u2013406. https:\/\/doi.org\/10.1007\/s12011-016-0852-7","journal-title":"Biol Trace Elem Res"},{"key":"2885_CR39","doi-asserted-by":"publisher","first-page":"586","DOI":"10.3382\/ps\/pev028","volume":"94","author":"S Mignon-Grasteau","year":"2015","unstructured":"Mignon-Grasteau S, Moreri U, Narcy A, Rousseau X, Rodenburg T, Tixier-Boichard M, Zerjal T (2015) Robustness to chronic heat stress in laying hens: a meta-analysis. Poult Sci 94:586\u2013600. https:\/\/doi.org\/10.3382\/ps\/pev028","journal-title":"Poult Sci"},{"key":"2885_CR40","doi-asserted-by":"publisher","unstructured":"de Moura DJ, Vercellino RDA, Santos JPA, do Vale MM Heat stress impact on weight gain in broiler chickens: a meta-analytical study of environmental factor that impact production losses. In: ASABE 1st Climate Change Symposium: Adaptation and Mitigation Conference Proceedings, 2015. American Society of Agricultural and Biological Engineers, pp 1\u20133. https:\/\/doi.org\/10.13031\/cc.20152143764","DOI":"10.13031\/cc.20152143764"},{"key":"2885_CR41","doi-asserted-by":"publisher","first-page":"4471","DOI":"10.1002\/jsfa.8971","volume":"98","author":"X He","year":"2018","unstructured":"He X, Lu Z, Ma B, Zhang L, Li J, Jiang Y, Zhou G, Gao F (2018) Effects of chronic heat exposure on growth performance, intestinal epithelial histology, appetite-related hormones and genes expression in broilers. J Sci Food Agric 98:4471\u20134478","journal-title":"J Sci Food Agric"},{"key":"2885_CR42","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1590\/S1516-635X2010000400010","volume":"12","author":"M Vale","year":"2010","unstructured":"Vale M, Moura D, N\u00e4\u00e4s I, Pereira D (2010) Characterization of heat waves affecting mortality rates of broilers between 29 days and market age. Braz J Poult Sci 12:279\u2013285. https:\/\/doi.org\/10.1590\/S1516-635X2010000400010","journal-title":"Braz J Poult Sci"},{"key":"2885_CR43","doi-asserted-by":"publisher","first-page":"3767","DOI":"10.3382\/ps\/pey243","volume":"97","author":"X Aver\u00f3s","year":"2018","unstructured":"Aver\u00f3s X, Estevez I (2018) Meta-analysis of the effects of intensive rearing environments on the performance and welfare of broiler chickens. Poult Sci 97:3767\u20133785. https:\/\/doi.org\/10.3382\/ps\/pey243","journal-title":"Poult Sci"},{"key":"2885_CR44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12889-015-2171-x","volume":"15","author":"I Young","year":"2015","unstructured":"Young I, Waddell L, Harding S, Greig J, Mascarenhas M, Sivaramalingam B, Pham MT, Papadopoulos A (2015) A systematic review and meta-analysis of the effectiveness of food safety education interventions for consumers in developed countries. BMC Public Health 15:1\u201314. https:\/\/doi.org\/10.1186\/s12889-015-2171-x","journal-title":"BMC Public Health"},{"key":"2885_CR45","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13643-019-1220-4","volume":"9","author":"SE Brennan","year":"2020","unstructured":"Brennan SE, McDonald S, Page MJ, Reid J, Ward S, Forbes AB, McKenzie JE (2020) Long-term effects of alcohol consumption on cognitive function: a systematic review and dose-response analysis of evidence published between 2007 and 2018. Syst Rev 9:1\u201339. https:\/\/doi.org\/10.1186\/s13643-019-1220-4","journal-title":"Syst Rev"},{"key":"2885_CR46","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1007\/s12011-016-0899-5","volume":"178","author":"M Safdari-Rostamabad","year":"2017","unstructured":"Safdari-Rostamabad M, Hosseini-Vashan SJ, Perai AH, Sarir H (2017) Nanoselenium supplementation of heat-stressed broilers: effects on performance, carcass characteristics, blood metabolites, immune response, antioxidant status, and jejunal morphology. Biol Trace Elem Res 178:105\u2013116. https:\/\/doi.org\/10.1007\/s12011-016-0899-5","journal-title":"Biol Trace Elem Res"},{"key":"2885_CR47","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.jtherbio.2019.02.025","volume":"81","author":"X He","year":"2019","unstructured":"He X, Lu Z, Ma B, Zhang L, Li J, Jiang Y, Zhou G, Gao F (2019) Chronic heat stress alters hypothalamus integrity, the serum indexes and attenuates expressions of hypothalamic appetite genes in broilers. J Therm Biol 81:110\u2013117. https:\/\/doi.org\/10.1016\/j.jtherbio.2019.02.025","journal-title":"J Therm Biol"},{"key":"2885_CR48","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/S0306-4565(98)00042-4","volume":"24","author":"S Yahav","year":"1999","unstructured":"Yahav S (1999) The effect of constant and diurnal cyclic temperatures on performance and blood system of young turkeys. J Therm Biol 24:71\u201378. https:\/\/doi.org\/10.1016\/S0306-4565(98)00042-4","journal-title":"J Therm Biol"},{"key":"2885_CR49","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1007\/s12011-018-1485-9","volume":"189","author":"C Orhan","year":"2019","unstructured":"Orhan C, Tuzcu M, Deeh PBD, Sahin N, Komorowski JR, Sahin K (2019) Organic chromium form alleviates the detrimental effects of heat stress on nutrient digestibility and nutrient transporters in laying hens. Biol Trace Elem Res 189:529\u2013537. https:\/\/doi.org\/10.1007\/s12011-018-1485-9","journal-title":"Biol Trace Elem Res"},{"key":"2885_CR50","doi-asserted-by":"publisher","unstructured":"Li R, Zhou Y, Li Y, Guo L, Zhang Y, Qi Z (2018) Effects of chromium picolinate supplementation on growth performance, small intestine morphology and antioxidant status in ducks under heat stress conditions. Int J Morphol 36:226\u201334. https:\/\/doi.org\/10.4067\/S0717-95022018000100226","DOI":"10.4067\/S0717-95022018000100226"},{"key":"2885_CR51","doi-asserted-by":"publisher","first-page":"878","DOI":"10.3382\/ps\/pey433","volume":"98","author":"Z Lu","year":"2019","unstructured":"Lu Z, He X, Ma B, Zhang L, Li J, Jiang Y, Zhou G, Gao F (2019) The alleviative effects and related mechanisms of taurine supplementation on growth performance and carcass characteristics in broilers exposed to chronic heat stress. Poult Sci 98:878\u2013886. https:\/\/doi.org\/10.3382\/ps\/pey433","journal-title":"Poult Sci"},{"key":"2885_CR52","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1017\/S0007114518000247","volume":"119","author":"Z Lu","year":"2018","unstructured":"Lu Z, He X, Ma B, Zhang L, Li J, Jiang Y, Zhou G, Gao F (2018) Serum metabolomics study of nutrient metabolic variations in chronic heat-stressed broilers. Br J Nutr 119:771\u2013781. https:\/\/doi.org\/10.1017\/S0007114518000247","journal-title":"Br J Nutr"},{"key":"2885_CR53","doi-asserted-by":"publisher","first-page":"1284","DOI":"10.4065\/75.12.1284","volume":"75","author":"VM Montori","year":"2000","unstructured":"Montori VM, Smieja M, Guyatt GH (2000) Publication bias: a brief review for clinicians. Mayo Clin Proc 75:1284\u20131288. https:\/\/doi.org\/10.4065\/75.12.1284","journal-title":"Mayo Clin Proc"},{"key":"2885_CR54","doi-asserted-by":"publisher","unstructured":"Sedgwick P (2015) What is publication bias in a meta-analysis? Bmj 351. https:\/\/doi.org\/10.1136\/bmj.h4419","DOI":"10.1136\/bmj.h4419"},{"key":"2885_CR55","doi-asserted-by":"publisher","unstructured":"Fragkos KC, Tsagris M, Frangos CC (2014) Publication bias in meta-analysis: confidence intervals for Rosenthal\u2019s fail-safe number. Int Sch Res Not 2014. https:\/\/doi.org\/10.1155\/2014\/825383","DOI":"10.1155\/2014\/825383"},{"key":"2885_CR56","doi-asserted-by":"publisher","first-page":"1096","DOI":"10.3382\/ps\/pew018","volume":"95","author":"M Brooks","year":"2016","unstructured":"Brooks M, Grimes J, Lloyd K, Krafka K, Lamptey A, Spears J (2016) Chromium propionate in broilers: effect on insulin sensitivity. Poult Sci 95:1096\u20131104. https:\/\/doi.org\/10.3382\/ps\/pew018","journal-title":"Poult Sci"},{"key":"2885_CR57","first-page":"7","volume":"1","author":"Z Liu","year":"2010","unstructured":"Liu Z, Wu G, Zheng J, An J, Yang N, Xu G (2010) Supplemental chromium picolinate promotes growth of broiler chickens by enhancing insulin receptor gene expression. J Anim Sci Biotechnol 1:7\u201314","journal-title":"J Anim Sci Biotechnol"},{"key":"2885_CR58","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1159\/000353703","volume":"6","author":"Y Pan","year":"2013","unstructured":"Pan Y, Wu S, Dai H, Zhang H, Yue H, Qi G (2013) Solexa sequencing of microRNAs on chromium metabolism in broiler chicks. Lifestyle Genomics 6:137\u2013153. https:\/\/doi.org\/10.1159\/000353703","journal-title":"Lifestyle Genomics"},{"key":"2885_CR59","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.3390\/ani10091685","volume":"10","author":"AT Hung","year":"2020","unstructured":"Hung AT, Leury BJ, Sabin MA, Fahri F, DiGiacomo K, Lien T-F, Dunshea FR (2020) Nano chromium picolinate improves gene expression associated with insulin signaling in porcine skeletal muscle and adipose tissue. Animals 10:1685. https:\/\/doi.org\/10.3390\/ani10091685","journal-title":"Animals"},{"key":"2885_CR60","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1111\/jpn.12579","volume":"101","author":"D Gessner","year":"2017","unstructured":"Gessner D, Ringseis R, Eder K (2017) Potential of plant polyphenols to combat oxidative stress and inflammatory processes in farm animals. J Anim Physiol Anim Nutr 101:605\u2013628. https:\/\/doi.org\/10.1111\/jpn.12579","journal-title":"J Anim Physiol Anim Nutr"},{"key":"2885_CR61","doi-asserted-by":"publisher","first-page":"114553","DOI":"10.1016\/j.anifeedsci.2020.114553","volume":"267","author":"S Hosseini-Vashan","year":"2020","unstructured":"Hosseini-Vashan S, Sharifian M, Piray A, Fathi-Nasri M (2020) Growth performance, carcass and blood traits, immunity, jejunal morphology and meat quality of heat-stressed broiler chickens fed urea-treated pomegranate (Punica granatum L.) peel. Anim Feed Sci Technol 267:114553. https:\/\/doi.org\/10.1016\/j.anifeedsci.2020.114553","journal-title":"Anim Feed Sci Technol"},{"key":"2885_CR62","doi-asserted-by":"publisher","first-page":"35","DOI":"10.3390\/antiox10010035","volume":"10","author":"NK Emami","year":"2021","unstructured":"Emami NK, Jung U, Voy B, Dridi S (2021) Radical response: effects of heat stress-induced oxidative stress on lipid metabolism in the avian liver. Antioxidants 10:35. https:\/\/doi.org\/10.3390\/antiox10010035","journal-title":"Antioxidants"},{"key":"2885_CR63","doi-asserted-by":"publisher","first-page":"3695","DOI":"10.3382\/ps\/pez056","volume":"98","author":"Z Lu","year":"2019","unstructured":"Lu Z, He X, Ma B, Zhang L, Li J, Jiang Y, Zhou G, Gao F (2019) Increased fat synthesis and limited apolipoprotein B cause lipid accumulation in the liver of broiler chickens exposed to chronic heat stress. Poult Sci 98:3695\u20133704. https:\/\/doi.org\/10.3382\/ps\/pez056","journal-title":"Poult Sci"},{"key":"2885_CR64","doi-asserted-by":"publisher","first-page":"569","DOI":"10.5713\/ajas.17.0289","volume":"31","author":"G Chen","year":"2018","unstructured":"Chen G, Gao Z, Chu W, Cao Z, Li C, Zhao H (2018) Effects of chromium picolinate on fat deposition, activity and genetic expression of lipid metabolism-related enzymes in 21 day old Ross broilers. Asian-australas J Anim Sci 31:569. https:\/\/doi.org\/10.5713\/ajas.17.0289","journal-title":"Asian-australas J Anim Sci"},{"key":"2885_CR65","first-page":"101","volume":"1","author":"B Wu","year":"2017","unstructured":"Wu B (2017) Relationship between the chromium or chromium compounds on immune functions in animals. J Vet Med Health 1:101","journal-title":"J Vet Med Health"},{"key":"2885_CR66","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13567-018-0526-x","volume":"49","author":"C Berthault","year":"2018","unstructured":"Berthault C, Larcher T, H\u00e4rtle S, Vautherot J-F, Trapp-Fragnet L, Denesvre C (2018) Atrophy of primary lymphoid organs induced by Marek\u2019s disease virus during early infection is associated with increased apoptosis, inhibition of cell proliferation and a severe B-lymphopenia. Vet Res 49:1\u201318. https:\/\/doi.org\/10.1186\/s13567-018-0526-x","journal-title":"Vet Res"},{"key":"2885_CR67","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1111\/1440-1681.13144","volume":"46","author":"F Moradi","year":"2019","unstructured":"Moradi F, Maleki V, Saleh-Ghadimi S, Kooshki F, PourghassemGargari B (2019) Potential roles of chromium on inflammatory biomarkers in diabetes: a systematic. Clin Exp Pharmacol Physiol 46:975\u2013983. https:\/\/doi.org\/10.1111\/1440-1681.13144","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"2885_CR68","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.anifeedsci.2010.06.004","volume":"159","author":"N Sahin","year":"2010","unstructured":"Sahin N, Akdemir F, Tuzcu M, Hayirli A, Smith M, Sahin K (2010) Effects of supplemental chromium sources and levels on performance, lipid peroxidation and proinflammatory markers in heat-stressed quails. Anim Feed Sci Technol 159:143\u2013149. https:\/\/doi.org\/10.1016\/j.anifeedsci.2010.06.004","journal-title":"Anim Feed Sci Technol"},{"key":"2885_CR69","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1017\/S0043933917000472","volume":"73","author":"A Calefi","year":"2017","unstructured":"Calefi A, Quinteiro-Filho W, Ferreira A, Palermo-Neto J (2017) Neuroimmunomodulation and heat stress in poultry. Worlds Poult Sci J 73:493\u2013504. https:\/\/doi.org\/10.1017\/S0043933917000472","journal-title":"Worlds Poult Sci J"},{"key":"2885_CR70","doi-asserted-by":"publisher","first-page":"1905","DOI":"10.3382\/ps.2010-00812","volume":"89","author":"W Quinteiro-Filho","year":"2010","unstructured":"Quinteiro-Filho W, Ribeiro A, Ferraz-de-Paula V, Pinheiro M, Sakai M, S\u00e1 L, Ferreira A, Palermo-Neto J (2010) Heat stress impairs performance parameters, induces intestinal injury, and decreases macrophage activity in broiler chickens. Poult Sci 89:1905\u20131914. https:\/\/doi.org\/10.3382\/ps.2010-00812","journal-title":"Poult Sci"},{"key":"2885_CR71","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.anifeedsci.2016.11.002","volume":"223","author":"JP Madej","year":"2017","unstructured":"Madej JP, Nowaczyk RM, Janeczek M, Chr\u00f3szcz A, Korczy\u0144ski M (2017) The effect of dietary supplementation with chromium-enriched soya meal on lymphatic cells in caecal tonsil of laying hens. Anim Feed Sci Technol 223:53\u201358. https:\/\/doi.org\/10.1016\/j.anifeedsci.2016.11.002","journal-title":"Anim Feed Sci Technol"},{"key":"2885_CR72","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1111\/asj.12766","volume":"88","author":"X Wan","year":"2017","unstructured":"Wan X, Jiang L, Zhong H, Lu Y, Zhang L, Wang T (2017) Effects of enzymatically treated Artemisia annua L. on growth performance and some blood parameters of broilers exposed to heat stress. Anim Sci J 88:1239\u20131246. https:\/\/doi.org\/10.1111\/asj.12766","journal-title":"Anim Sci J"}],"container-title":["Biological Trace Element Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12011-021-02885-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12011-021-02885-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12011-021-02885-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T01:21:19Z","timestamp":1653528079000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12011-021-02885-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,20]]},"references-count":72,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["2885"],"URL":"https:\/\/doi.org\/10.1007\/s12011-021-02885-x","relation":{},"ISSN":["0163-4984","1559-0720"],"issn-type":[{"value":"0163-4984","type":"print"},{"value":"1559-0720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,20]]},"assertion":[{"value":"8 July 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 August 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 August 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}