{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T17:38:20Z","timestamp":1793122700871,"version":"4.5.0"},"reference-count":80,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T00:00:00Z","timestamp":1646006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T00:00:00Z","timestamp":1646006400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100004048","name":"Kashan University of Medical Sciences","doi-asserted-by":"publisher","award":["99012"],"award-info":[{"award-number":["99012"]}],"id":[{"id":"10.13039\/501100004048","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biol Trace Elem Res"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1007\/s12011-022-03178-7","type":"journal-article","created":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T00:02:20Z","timestamp":1646006540000},"page":"567-576","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["The Effect of Selenium Supplementation on Clinical Outcomes, Metabolic Profiles, and Pulsatility Index of the Uterine Artery in High-Risk Mothers in Terms of Preeclampsia Screening with Quadruple Test: a Randomized, Double-Blind, Placebo-Controlled Clinical Trial"],"prefix":"10.1007","volume":"201","author":[{"given":"Elahe","family":"Mesdaghinia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farah","family":"Shahin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Ghaderi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daryoush","family":"Shahin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Shariat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamidreza","family":"Banafshe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,2,28]]},"reference":[{"issue":"3","key":"3178_CR1","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1053\/j.semperi.2009.02.010","volume":"33","author":"L Duley","year":"2009","unstructured":"Duley L (2009) The global impact of pre-eclampsia and eclampsia. Semin Perinatol 33(3):130\u2013137","journal-title":"Semin Perinatol"},{"issue":"4","key":"3178_CR2","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1002\/uog.22174","volume":"58","author":"R Martinez-Portilla","year":"2021","unstructured":"Martinez-Portilla R et al (2021) Incidence of pre-eclampsia and other perinatal complications among pregnant women with congenital heart disease: systematic review and meta-analysis. Ultrasound Obstet Gynecol 58(4):519\u2013528","journal-title":"Ultrasound Obstet Gynecol"},{"key":"3178_CR3","unstructured":"Aali BS, Ghafoorian J, Mohamad-Alizadeh S (2004) Severe preeclampsia and eclampsia in Kerman, Iran: complications and outcomes. Med Sci Monit 10(4): CR163-CR167"},{"issue":"2018","key":"3178_CR4","first-page":"6268276","volume":"6","author":"J Mayrink","year":"2018","unstructured":"Mayrink J, Costa ML, Cecatti JG (2018) Preeclampsia in 2018: revisiting concepts, physiopathology, and prediction. Sci World J 6(2018):6268276","journal-title":"Sci World J"},{"issue":"1","key":"3178_CR5","doi-asserted-by":"publisher","first-page":"163","DOI":"10.2105\/AJPH.2005.068577","volume":"97","author":"M Tanaka","year":"2007","unstructured":"Tanaka M et al (2007) Racial disparity in hypertensive disorders of pregnancy in New York State: a 10-year longitudinal population-based study. Am J Public Health 97(1):163\u2013170","journal-title":"Am J Public Health"},{"issue":"1","key":"3178_CR6","doi-asserted-by":"publisher","first-page":"12708","DOI":"10.1038\/s41598-021-92189-w","volume":"11","author":"M Morikawa","year":"2021","unstructured":"Morikawa M et al (2021) Earlier onset of proteinuria or hypertension is a predictor of progression from gestational hypertension or gestational proteinuria to preeclampsia. Sci Rep 11(1):12708","journal-title":"Sci Rep"},{"issue":"1","key":"3178_CR7","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1002\/uog.21869","volume":"55","author":"LC Poon","year":"2020","unstructured":"Poon LC et al (2020) From first-trimester screening to risk stratification of evolving pre-eclampsia in the second and third trimesters of pregnancy: a comprehensive approach. Ultrasound Obstet Gynecol 55(1):5\u201312","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"10","key":"3178_CR8","doi-asserted-by":"publisher","first-page":"1625","DOI":"10.3390\/jcm8101625","volume":"8","author":"R Fox","year":"2019","unstructured":"Fox R et al (2019) Preeclampsia: risk factors, diagnosis, management, and the cardiovascular impact on the offspring. J Clin Med 8(10):1625","journal-title":"J Clin Med"},{"issue":"1","key":"3178_CR9","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1186\/s12884-021-03874-7","volume":"21","author":"N Stitterich","year":"2021","unstructured":"Stitterich N et al (2021) Risk factors for preeclampsia and eclampsia at a main referral maternity hospital in Freetown, Sierra Leone: a case-control study. BMC Pregnancy Childbirth 21(1):413","journal-title":"BMC Pregnancy Childbirth"},{"key":"3178_CR10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.preghy.2017.01.004","volume":"8","author":"RD Williamson","year":"2017","unstructured":"Williamson RD et al (2017) Oxidative stress in pre-eclampsia; have we been looking in the wrong place? Pregnancy Hypertens 8:1\u20135","journal-title":"Pregnancy Hypertens"},{"issue":"2019","key":"3178_CR11","first-page":"8238727","volume":"4","author":"MB Ten\u00f3rio","year":"2019","unstructured":"Ten\u00f3rio MB et al (2019) Cross-talk between oxidative stress and inflammation in preeclampsia. Oxid Med Cell Longev 4(2019):8238727","journal-title":"Oxid Med Cell Longev"},{"issue":"5","key":"3178_CR12","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1016\/j.numecd.2019.01.008","volume":"29","author":"H Yusuf","year":"2019","unstructured":"Yusuf H et al (2019) Associations of macro and micronutrients and antioxidants intakes with preeclampsia: A case-control study in Jordanian pregnant women. Nutr Metab Cardiovasc Dis 29(5):458\u2013466","journal-title":"Nutr Metab Cardiovasc Dis"},{"issue":"8","key":"3178_CR13","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1161\/CIRCULATIONAHA.118.036748","volume":"139","author":"SM Grandi","year":"2019","unstructured":"Grandi SM et al (2019) Cardiovascular disease-related morbidity and mortality in women with a history of pregnancy complications: systematic review and meta-analysis. Circulation 139(8):1069\u20131079","journal-title":"Circulation"},{"issue":"4","key":"3178_CR14","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1007\/s00737-019-01010-1","volume":"23","author":"L Caropreso","year":"2020","unstructured":"Caropreso L et al (2020) Preeclampsia as a risk factor for postpartum depression and psychosis: a systematic review and meta-analysis. Arch Womens Ment Health 23(4):493\u2013505","journal-title":"Arch Womens Ment Health"},{"issue":"20","key":"3178_CR15","doi-asserted-by":"publisher","first-page":"2510","DOI":"10.1080\/14767058.2016.1254185","volume":"30","author":"O Cetin","year":"2017","unstructured":"Cetin O et al (2017) Investigation of maternal psychopathological symptoms, dream anxiety and insomnia in preeclampsia. J Matern Fetal Neonatal Med 30(20):2510\u20132515","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"5","key":"3178_CR16","doi-asserted-by":"publisher","first-page":"609","DOI":"10.3390\/molecules21050609","volume":"21","author":"M Kieliszek","year":"2016","unstructured":"Kieliszek M, B\u0142a\u017cejak S (2016) Current knowledge on the importance of selenium in food for living organisms: a review. Molecules 21(5):609","journal-title":"Molecules"},{"issue":"3","key":"3178_CR17","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1007\/s12011-021-02716-z","volume":"200","author":"M Kieliszek","year":"2021","unstructured":"Kieliszek M, Bano I, Zare H (2021) A comprehensive review on selenium and its effects on human health and distribution in Middle Eastern Countries. Biol Trace Elem Res 200(3):971\u2013987","journal-title":"Biol Trace Elem Res"},{"issue":"5","key":"3178_CR18","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1016\/j.nut.2012.11.012","volume":"29","author":"M Kieliszek","year":"2013","unstructured":"Kieliszek M, B\u0142a\u017cejak S (2013) Selenium: significance, and outlook for supplementation. Nutrition 29(5):713\u2013718","journal-title":"Nutrition"},{"issue":"7","key":"3178_CR19","doi-asserted-by":"publisher","first-page":"1298","DOI":"10.3390\/molecules24071298","volume":"24","author":"M Kieliszek","year":"2019","unstructured":"Kieliszek M (2019) Selenium-fascinating microelement, properties and sources in food. Molecules 24(7):1298","journal-title":"Molecules"},{"issue":"46","key":"3178_CR20","doi-asserted-by":"publisher","first-page":"24036","DOI":"10.1074\/jbc.M116.756155","volume":"291","author":"VN Gladyshev","year":"2016","unstructured":"Gladyshev VN et al (2016) Selenoprotein gene nomenclature. J Biol Chem 291(46):24036\u201324040","journal-title":"J Biol Chem"},{"key":"3178_CR21","first-page":"60","volume":"3","author":"B Ruseva","year":"2013","unstructured":"Ruseva B, Himcheva I, Nankova D (2013) Importance of selenoproteins for the function of the thyroid gland. Medicine 3:60\u201364","journal-title":"Medicine"},{"issue":"1","key":"3178_CR22","doi-asserted-by":"publisher","first-page":"54","DOI":"10.5114\/wo.2010.979","volume":"14","author":"K Zab\u0142ocka","year":"2010","unstructured":"Zab\u0142ocka K, Biernat J (2010) The influence of selected nutritional components in lung cancer risk \u2013 unsaturated fatty acids, isothiocyanates, selenium. Contemporary Oncology\/Wsp\u00f3\u0142czesna Onkologia 14(1):54\u201358. https:\/\/doi.org\/10.5114\/wo.2010.979","journal-title":"Contemporary Oncology\/Wsp\u00f3\u0142czesna Onkologia"},{"key":"3178_CR23","doi-asserted-by":"crossref","unstructured":"Tang C et al (2020) Selenium deficiency-induced redox imbalance leads to metabolic reprogramming and inflammation in the liver. Redox Biol 36:101519.","DOI":"10.1016\/j.redox.2020.101519"},{"key":"3178_CR24","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.mehy.2017.10.021","volume":"110","author":"M Kieliszek","year":"2018","unstructured":"Kieliszek M, Lipinski B (2018) Pathophysiological significance of protein hydrophobic interactions: An emerging hypothesis. Med Hypotheses 110:15\u201322","journal-title":"Med Hypotheses"},{"issue":"2","key":"3178_CR25","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1007\/s12011-017-1042-y","volume":"181","author":"FNC Vaz","year":"2018","unstructured":"Vaz FNC et al (2018) The relationship between copper, iron, and selenium levels and alzheimer disease. Biol Trace Elem Res 181(2):185\u2013191","journal-title":"Biol Trace Elem Res"},{"key":"3178_CR26","first-page":"1","volume":"5","author":"M Fakhrolmobasheri","year":"2021","unstructured":"Fakhrolmobasheri M et al (2021) COVID-19 and selenium deficiency: a systematic review. Biol Trace Elem Res 5:1\u201312","journal-title":"Biol Trace Elem Res"},{"issue":"1","key":"3178_CR27","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1385\/BTER:109:1:015","volume":"109","author":"CC Lin","year":"2006","unstructured":"Lin CC et al (2006) Selenium, iron, copper, and zinc levels and copper-to-zinc ratios in serum of patients at different stages of viral hepatic diseases. Biol Trace Elem Res 109(1):15\u201324","journal-title":"Biol Trace Elem Res"},{"key":"3178_CR28","doi-asserted-by":"publisher","unstructured":"Sharma P et al (2022) Assessment of Serum elements concentration and polycystic ovary syndrome (PCOS): systematic review and meta-analysis. Biol Trace Elem Res. https:\/\/doi.org\/10.1007\/s12011-021-03058-6","DOI":"10.1007\/s12011-021-03058-6"},{"issue":"1\u20133","key":"3178_CR29","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/S0048-9697(99)00526-4","volume":"249","author":"M Navarro-Alarc\u00f3n","year":"2000","unstructured":"Navarro-Alarc\u00f3n M, L\u00f3pez-Mart\u00ednez MC (2000) Essentiality of selenium in the human body: relationship with different diseases. Sci Total Environ 249(1\u20133):347\u2013371","journal-title":"Sci Total Environ"},{"issue":"1","key":"3178_CR30","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.ajog.2011.07.034","volume":"206","author":"HD Mistry","year":"2012","unstructured":"Mistry HD et al (2012) Selenium in reproductive health. Am J Obstet Gynecol 206(1):21\u201330","journal-title":"Am J Obstet Gynecol"},{"issue":"2","key":"3178_CR31","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.jtemb.2009.02.005","volume":"23","author":"M Zadro\u017cna","year":"2009","unstructured":"Zadro\u017cna M et al (2009) Antioxidants activities and concentration of selenium, zinc and copper in preterm and IUGR human placentas. J Trace Elem Med Biol 23(2):144\u2013148","journal-title":"J Trace Elem Med Biol"},{"key":"3178_CR32","doi-asserted-by":"crossref","unstructured":"Eze SC et al (2020) Serum selenium levels of pre-eclamptic and normal pregnant women in Nigeria: A comparative study. PLoS One 27;15(8):e0238263.","DOI":"10.1371\/journal.pone.0238263"},{"issue":"5","key":"3178_CR33","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1055\/s-0038-1660777","volume":"40","author":"MA Pedroso","year":"2018","unstructured":"Pedroso MA et al (2018) Uterine artery Doppler in screening for preeclampsia and fetal growth restriction. Rev Bras Ginecol Obstet 40(5):287\u2013293","journal-title":"Rev Bras Ginecol Obstet"},{"issue":"6","key":"3178_CR34","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1503\/cmaj.070430","volume":"178","author":"JS Cnossen","year":"2008","unstructured":"Cnossen JS et al (2008) Use of uterine artery Doppler ultrasonography to predict pre-eclampsia and intrauterine growth restriction: a systematic review and bivariable meta-analysis. CMAJ 178(6):701\u2013711","journal-title":"CMAJ"},{"key":"3178_CR35","doi-asserted-by":"publisher","unstructured":"Rashid M et al (2020) Uterine artery Doppler indices as predictive measures for the pre-eclampsia and intrauterine growth restriction. Biological and Clinical Sciences Research Journal 2020(1). https:\/\/doi.org\/10.54112\/bcsrj.v2020i1.23","DOI":"10.54112\/bcsrj.v2020i1.23"},{"issue":"1","key":"3178_CR36","doi-asserted-by":"publisher","first-page":"21","DOI":"10.2174\/1573402114666180416160425","volume":"14","author":"F Abdi","year":"2018","unstructured":"Abdi F et al (2018) A systematic review of first trimester biochemical and molecular predictive tests for preeclampsia. Curr Hypertens Rev 14(1):21\u201328","journal-title":"Curr Hypertens Rev"},{"issue":"1","key":"3178_CR37","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1186\/s12884-020-03298-9","volume":"20","author":"R Boonpiam","year":"2020","unstructured":"Boonpiam R et al (2020) Quad test for fetal aneuploidy screening as a predictor of small-for-gestational age fetuses: a population-based study. BMC Pregnancy Childbirth 20(1):621","journal-title":"BMC Pregnancy Childbirth"},{"key":"3178_CR38","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1016\/j.cca.2020.10.029","volume":"511","author":"CY Yue","year":"2020","unstructured":"Yue CY, Zhang CY, Ying CM (2020) Serum markers in quadruple screening associated with adverse pregnancy outcomes: a case-control study in China. Clin Chim Acta 511:278\u2013281","journal-title":"Clin Chim Acta"},{"issue":"2","key":"3178_CR39","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1007\/BF00488201","volume":"316","author":"B Welz","year":"1983","unstructured":"Welz B, Melcher M, Schlemmer G (1983) Determination of selenium in human blood serum. Comparison of two atomic-absorption spectrometric procedures. Z Anal Chem 316(2):271\u2013276","journal-title":"Z Anal Chem"},{"issue":"1","key":"3178_CR40","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1006\/abio.1996.0292","volume":"239","author":"IF Benzie","year":"1996","unstructured":"Benzie IF, Strain JJ (1996) The ferric reducing ability of plasma (FRAP) as a measure of \u201cantioxidant power\u201d: the FRAP assay. Anal Biochem 239(1):70\u201376","journal-title":"Anal Biochem"},{"key":"3178_CR41","doi-asserted-by":"publisher","unstructured":"Tipple TE, Rogers LK (2012) Methods for the determination of plasma or tissue glutathione levels. In: Harris C., Hansen J. (eds) Developmental Toxicology. Methods in Molecular Biology (Methods and Protocols), vol 889. Humana Press, Totowa, NJ. https:\/\/doi.org\/10.1007\/978-1-61779-867-2_20","DOI":"10.1007\/978-1-61779-867-2_20"},{"issue":"6","key":"3178_CR42","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/0891-5849(90)90131-2","volume":"9","author":"DR Janero","year":"1990","unstructured":"Janero DR (1990) Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury. Free Radic Biol Med 9(6):515\u2013540","journal-title":"Free Radic Biol Med"},{"issue":"4","key":"3178_CR43","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1016\/j.clinbiochem.2010.12.011","volume":"44","author":"E Tatsch","year":"2011","unstructured":"Tatsch E et al (2011) A simple and inexpensive automated technique for measurement of serum nitrite\/nitrate. Clin Biochem 44(4):348\u2013350","journal-title":"Clin Biochem"},{"issue":"1","key":"3178_CR44","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1159\/000335366","volume":"31","author":"L Poon","year":"2012","unstructured":"Poon L et al (2012) Protocol for measurement of mean arterial pressure at 11\u201313 weeks\u2019 gestation. Fetal Diagn Ther 31(1):42\u201348","journal-title":"Fetal Diagn Ther"},{"issue":"1","key":"3178_CR45","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/0272-7358(88)90050-5","volume":"8","author":"AT Beck","year":"1988","unstructured":"Beck AT, Steer RA, Carbin MG (1988) Psychometric properties of the Beck Depression Inventory: twenty-five years of evaluation. Clin Psychol Rev 8(1):77\u2013100","journal-title":"Clin Psychol Rev"},{"issue":"6","key":"3178_CR46","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1001\/archpsyc.1961.01710120031004","volume":"4","author":"AT Beck","year":"1961","unstructured":"Beck AT et al (1961) An inventory for measuring depression. Arch Gen Psychiatry 4(6):561\u2013571","journal-title":"Arch Gen Psychiatry"},{"issue":"2","key":"3178_CR47","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/0165-1781(89)90047-4","volume":"28","author":"DJ Buysse","year":"1989","unstructured":"Buysse DJ et al (1989) The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res 28(2):193\u2013213","journal-title":"Psychiatry Res"},{"issue":"27","key":"3178_CR48","first-page":"37","volume":"7","author":"M Rafiei","year":"2013","unstructured":"Rafiei M, Seifi A (2013) An investigation into the reliability and validity of beck anxiety inventory among the university students. JTBCP 7(27):37\u201346","journal-title":"JTBCP"},{"issue":"10","key":"3178_CR49","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1097\/NMD.0000000000000183","volume":"202","author":"S Vasegh","year":"2014","unstructured":"Vasegh S, Baradaran N (2014) Using the Persian-language version of the Beck Depression Inventory-II (BDI-II-Persian) for the screening of depression in students. J Nerv Ment Dis 202(10):738\u2013744","journal-title":"J Nerv Ment Dis"},{"issue":"1","key":"3178_CR50","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1007\/s12011-016-0911-0","volume":"178","author":"E Mesdaghinia","year":"2017","unstructured":"Mesdaghinia E et al (2017) Clinical and metabolic response to selenium supplementation in pregnant women at risk for intrauterine growth restriction: randomized, double-blind, placebo-controlled trial. Biol Trace Elem Res 178(1):14\u201321","journal-title":"Biol Trace Elem Res"},{"issue":"1","key":"3178_CR51","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1017\/S0007114514000531","volume":"112","author":"MP Rayman","year":"2014","unstructured":"Rayman MP et al (2014) Effect of selenium on markers of risk of pre-eclampsia in UK pregnant women: a randomised, controlled pilot trial. Br J Nutr 112(1):99\u2013111","journal-title":"Br J Nutr"},{"key":"3178_CR52","doi-asserted-by":"publisher","unstructured":"Fordyce FM (2013) Selenium Deficiency and Toxicity in the Environment. In: Selinus O. (eds) Essentials of Medical Geology. Springer, Dordrecht. https:\/\/doi.org\/10.1007\/978-94-007-4375-5_16.","DOI":"10.1007\/978-94-007-4375-5_16"},{"issue":"1","key":"3178_CR53","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1186\/1735-2746-9-11","volume":"9","author":"L Nazemi","year":"2012","unstructured":"Nazemi L et al (2012) Selenium status in soil, water and essential crops of Iran. Iranian J Environ Health Sci Eng 9(1):11","journal-title":"Iranian J Environ Health Sci Eng"},{"issue":"4","key":"3178_CR54","doi-asserted-by":"publisher","first-page":"804","DOI":"10.1158\/1055-9965.EPI-05-0950","volume":"15","author":"RF Burk","year":"2006","unstructured":"Burk RF et al (2006) Effects of chemical form of selenium on plasma biomarkers in a high-dose human supplementation trial. Cancer Epidemiol Biomarkers Prev 15(4):804\u2013810","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"1","key":"3178_CR55","doi-asserted-by":"publisher","first-page":"57","DOI":"10.3109\/15563650.2011.641560","volume":"50","author":"BM Aldosary","year":"2012","unstructured":"Aldosary BM et al (2012) Case series of selenium toxicity from a nutritional supplement. Clin Toxicol (Phila) 50(1):57\u201364","journal-title":"Clin Toxicol (Phila)"},{"issue":"2","key":"3178_CR56","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/S1028-4559(10)60038-1","volume":"49","author":"F Tara","year":"2010","unstructured":"Tara F et al (2010) Selenium supplementation and the incidence of preeclampsia in pregnant Iranian women: a randomized, double-blind, placebo-controlled pilot trial. Taiwan J Obstet Gynecol 49(2):181\u2013187","journal-title":"Taiwan J Obstet Gynecol"},{"issue":"9225","key":"3178_CR57","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/S0140-6736(00)02490-9","volume":"356","author":"MP Rayman","year":"2000","unstructured":"Rayman MP (2000) The importance of selenium to human health. Lancet 356(9225):233\u2013241","journal-title":"Lancet"},{"issue":"6","key":"3178_CR58","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1002\/uog.2814","volume":"28","author":"O G\u00f3mez","year":"2006","unstructured":"G\u00f3mez O et al (2006) Sequential changes in uterine artery blood flow pattern between the first and second trimesters of gestation in relation to pregnancy outcome. Ultrasound Obstet Gynecol 28(6):802\u2013808","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"1","key":"3178_CR59","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s12011-010-8637-x","volume":"139","author":"MO \u00d6zkaya","year":"2011","unstructured":"\u00d6zkaya MO et al (2011) Effects of multivitamin\/mineral supplementation on trace element levels in serum and follicular fluid of women undergoing in vitro fertilization (IVF). Biol Trace Elem Res 139(1):1\u20139","journal-title":"Biol Trace Elem Res"},{"issue":"6","key":"3178_CR60","doi-asserted-by":"publisher","first-page":"2465","DOI":"10.1016\/j.fertnstert.2010.01.066","volume":"94","author":"MO Ozkaya","year":"2010","unstructured":"Ozkaya MO, Naz\u0131ro\u011flu M (2010) Multivitamin and mineral supplementation modulates oxidative stress and antioxidant vitamin levels in serum and follicular fluid of women undergoing in vitro fertilization. Fertil Steril 94(6):2465\u20132466","journal-title":"Fertil Steril"},{"issue":"2","key":"3178_CR61","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1007\/s12011-019-1636-7","volume":"191","author":"A Kamali","year":"2019","unstructured":"Kamali A, Amirani E, Asemi Z (2019) Effects of selenium supplementation on metabolic status in patients undergoing for coronary artery bypass grafting (CABG) surgery: a randomized, double-blind, placebo-controlled trial. Biol Trace Elem Res 191(2):331\u2013337","journal-title":"Biol Trace Elem Res"},{"issue":"2","key":"3178_CR62","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1007\/s12011-013-9616-9","volume":"152","author":"VA Y\u00fcrekli","year":"2013","unstructured":"Y\u00fcrekli VA, Naz\u0131ro\u011flu M (2013) Selenium and topiramate attenuates blood oxidative toxicity in patients with epilepsy: a clinical pilot study. Biol Trace Elem Res 152(2):180\u2013186","journal-title":"Biol Trace Elem Res"},{"key":"3178_CR63","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.jtemb.2017.04.009","volume":"44","author":"W Ju","year":"2017","unstructured":"Ju W et al (2017) The effect of selenium supplementation on coronary heart disease: a systematic review and meta-analysis of randomized controlled trials. J Trace Elem Med Biol 44:8\u201316","journal-title":"J Trace Elem Med Biol"},{"key":"3178_CR64","doi-asserted-by":"crossref","unstructured":"Savory LA (2012) et al., Selenium supplementation and exercise: effect on oxidant stress in overweight adults. Obesity (Silver Spring) 20(4):794\u2013801.","DOI":"10.1038\/oby.2011.83"},{"issue":"2","key":"3178_CR65","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1007\/s12011-014-9929-3","volume":"158","author":"SA K\u00f6se","year":"2014","unstructured":"K\u00f6se SA, Naz\u0131ro\u011flu M (2014) Selenium reduces oxidative stress and calcium entry through TRPV1 channels in the neutrophils of patients with polycystic ovary syndrome. Biol Trace Elem Res 158(2):136\u2013142","journal-title":"Biol Trace Elem Res"},{"issue":"3","key":"3178_CR66","doi-asserted-by":"publisher","first-page":"106","DOI":"10.4103\/0019-5154.39577","volume":"53","author":"IC Ozturk","year":"2008","unstructured":"Ozturk IC et al (2008) Comparison of plasma malondialdehyde, glutathione, glutathione peroxidase, hydroxyproline and selenium levels in patients with vitiligo and healthy controls. Indian J Dermatol 53(3):106\u2013110","journal-title":"Indian J Dermatol"},{"issue":"7","key":"3178_CR67","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1016\/j.jnutbio.2008.05.012","volume":"20","author":"J Zeng","year":"2009","unstructured":"Zeng J, Zhou J, Huang K (2009) Effect of selenium on pancreatic proinflammatory cytokines in streptozotocin-induced diabetic mice. J Nutr Biochem 20(7):530\u2013536","journal-title":"J Nutr Biochem"},{"issue":"5","key":"3178_CR68","doi-asserted-by":"publisher","first-page":"703","DOI":"10.3748\/wjg.v10.i5.703","volume":"10","author":"YT He","year":"2004","unstructured":"He YT et al (2004) Therapeutic effects and molecular mechanisms of anti-fibrosis herbs and selenium on rats with hepatic fibrosis. World J Gastroenterol 10(5):703\u2013706","journal-title":"World J Gastroenterol"},{"issue":"2","key":"3178_CR69","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/0006-3223(95)00085-2","volume":"39","author":"WC Hawkes","year":"1996","unstructured":"Hawkes WC, Hornbostel L (1996) Effects of dietary selenium on mood in healthy men living in a metabolic research unit. Biol Psychiatry 39(2):121\u2013128","journal-title":"Biol Psychiatry"},{"issue":"9","key":"3178_CR70","doi-asserted-by":"publisher","first-page":"1421","DOI":"10.1111\/1471-0528.16683","volume":"128","author":"T Pittara","year":"2021","unstructured":"Pittara T et al (2021) Pre-eclampsia and long-term health outcomes for mother and infant: an umbrella review. BJOG 128(9):1421\u20131430","journal-title":"BJOG"},{"issue":"4","key":"3178_CR71","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1080\/00016340801915127","volume":"87","author":"I Bruss\u00e9","year":"2008","unstructured":"Bruss\u00e9 I et al (2008) Impaired maternal cognitive functioning after pregnancies complicated by severe pre-eclampsia: a pilot case-control study. Acta Obstet Gynecol Scand 87(4):408\u2013412","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"2","key":"3178_CR72","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/j.genhosppsych.2012.11.006","volume":"35","author":"P Thiagayson","year":"2013","unstructured":"Thiagayson P et al (2013) Depression and anxiety in Singaporean high-risk pregnancies - prevalence and screening. Gen Hosp Psychiatry 35(2):112\u2013116","journal-title":"Gen Hosp Psychiatry"},{"issue":"2","key":"3178_CR73","first-page":"156","volume":"82","author":"K Gruca-Stryjak","year":"2014","unstructured":"Gruca-Stryjak K et al (2014) Is there a relationship between pregnancy induced hypertension and obstructive sleep apnea? Case report. Pneumonol Alergol Pol 82(2):156\u2013162","journal-title":"Pneumonol Alergol Pol"},{"issue":"1","key":"3178_CR74","doi-asserted-by":"publisher","first-page":"104","DOI":"10.3109\/14767058.2010.482598","volume":"24","author":"N Mokhber","year":"2011","unstructured":"Mokhber N et al (2011) Effect of supplementation with selenium on postpartum depression: a randomized double-blind placebo-controlled trial. J Matern Fetal Neonatal Med 24(1):104\u2013108","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"1","key":"3178_CR75","doi-asserted-by":"publisher","first-page":"55","DOI":"10.2190\/PFFD-D920-V041-N5KD","volume":"33","author":"G Shor-Posner","year":"2003","unstructured":"Shor-Posner G et al (2003) Psychological burden in the era of HAART: impact of selenium therapy. Int J Psychiatry Med 33(1):55\u201369","journal-title":"Int J Psychiatry Med"},{"issue":"3","key":"3178_CR76","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1007\/s11325-019-01816-4","volume":"23","author":"RG Albuquerque","year":"2019","unstructured":"Albuquerque RG, Tufik S, Andersen ML (2019) Benefits of selenium in the treatment of depression and sleep disorders. Sleep Breath 23(3):933\u2013934","journal-title":"Sleep Breath"},{"issue":"2","key":"3178_CR77","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1007\/s12199-007-0019-4","volume":"13","author":"U Tinggi","year":"2008","unstructured":"Tinggi U (2008) Selenium: its role as antioxidant in human health. Environ Health Prev Med 13(2):102\u2013108","journal-title":"Environ Health Prev Med"},{"key":"3178_CR78","doi-asserted-by":"publisher","first-page":"630016","DOI":"10.3389\/fnins.2021.630016","volume":"15","author":"N Solovyev","year":"2021","unstructured":"Solovyev N et al (2021) Selenium at the neural barriers: a review. Front Neurosci 15:630016","journal-title":"Front Neurosci"},{"key":"3178_CR79","doi-asserted-by":"publisher","first-page":"144329","DOI":"10.1016\/j.scitotenv.2020.144329","volume":"767","author":"M Naderi","year":"2021","unstructured":"Naderi M et al (2021) A comprehensive review on the neuropathophysiology of selenium. Sci Total Environ 767:144329","journal-title":"Sci Total Environ"},{"issue":"7","key":"3178_CR80","doi-asserted-by":"publisher","first-page":"944","DOI":"10.1210\/er.2001-0034","volume":"26","author":"J Kohrle","year":"2005","unstructured":"Kohrle J et al (2005) Selenium, the thyroid, and the endocrine system. Endocr Rev 26(7):944\u2013984","journal-title":"Endocr Rev"}],"container-title":["Biological Trace Element Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12011-022-03178-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12011-022-03178-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12011-022-03178-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T23:29:07Z","timestamp":1744154947000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12011-022-03178-7"}},"subtitle":["Selenium and preeclampsia"],"short-title":[],"issued":{"date-parts":[[2022,2,28]]},"references-count":80,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["3178"],"URL":"https:\/\/doi.org\/10.1007\/s12011-022-03178-7","relation":{},"ISSN":["0163-4984","1559-0720"],"issn-type":[{"value":"0163-4984","type":"print"},{"value":"1559-0720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,28]]},"assertion":[{"value":"20 December 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 February 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 February 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"At the beginning of the questionnaire distribution session, the purpose of the study was explained for the participants and they were assured about the anonymity and confidentiality of their responses. All participants gave their signed written informed consent letters. The study protocol was approved by the Ethics Committee of Kashan University of Medical Sciences \u201capproval no; IR.KAUMS.MEDNT.REC.1399.008\u201d. All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval and Consent to Participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}