{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T18:35:27Z","timestamp":1781202927055,"version":"3.54.1"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T00:00:00Z","timestamp":1664409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T00:00:00Z","timestamp":1664409600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"KOSGEB, Elazig, Turkey"},{"DOI":"10.13039\/501100004412","name":"T\u00fcrkiye Bilimler Akademisi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004412","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biol Trace Elem Res"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1007\/s12011-022-03433-x","type":"journal-article","created":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T16:07:26Z","timestamp":1664467646000},"page":"1377-1387","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Combination of Phycocyanin, Zinc, and Selenium Improves Survival Rate and Inflammation in\u00a0the Lipopolysaccharide-Galactosamine Mouse Model"],"prefix":"10.1007","volume":"201","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9592-5986","authenticated-orcid":false,"given":"Pinar","family":"Oner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9583-2218","authenticated-orcid":false,"given":"Besir","family":"Er","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4138-7689","authenticated-orcid":false,"given":"Cemal","family":"Orhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9542-5244","authenticated-orcid":false,"given":"Kazim","family":"Sahin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,9,29]]},"reference":[{"key":"3433_CR1","doi-asserted-by":"publisher","first-page":"111890","DOI":"10.1016\/j.biopha.2021.111890","volume":"141","author":"EG P\u2019erez-Hernandez","year":"2021","unstructured":"P\u2019erez-Hernandez EG, Delgado-Coello B, Luna-Reyes I, Mas-Oliva J (2021) New insights into lipopolysaccharide inactivation mechanisms in sepsis. Biomed Pharmacother 141:111890. https:\/\/doi.org\/10.1016\/j.biopha.2021.111890","journal-title":"Biomed Pharmacother"},{"issue":"1","key":"3433_CR2","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1186\/s12929-017-0370-8","volume":"24","author":"S Seemann","year":"2017","unstructured":"Seemann S, Zohles F, Lupp A (2017) Comprehensive comparison of three different animal models for systemic inflammation. J Biomed Sci 24(1):60. https:\/\/doi.org\/10.1186\/s12929-017-0370-8","journal-title":"J Biomed Sci"},{"key":"3433_CR3","doi-asserted-by":"publisher","first-page":"108920","DOI":"10.1016\/j.jnutbio.2021.108920","volume":"101","author":"JH Azambuja","year":"2022","unstructured":"Azambuja JH, Mancuso RI, Della Via FI, Torello CO, Saad STO (2022) Protective effect of green tea and epigallocatechin-3-gallate in a LPS-induced systemic inflammation model. J Nutr Biochem 101:108920. https:\/\/doi.org\/10.1016\/j.jnutbio.2021.108920","journal-title":"J Nutr Biochem"},{"issue":"5","key":"3433_CR4","doi-asserted-by":"publisher","first-page":"814","DOI":"10.3390\/antiox10050814","volume":"10","author":"M Keller","year":"2021","unstructured":"Keller M, Manzocchi E, Rentsch D, Lugar\u00e0 R, Giller K (2021) Antioxidant and inflammatory gene expression profiles of bovine peripheral blood mononuclear cells in response to Arthrospira platensis before and after LPS challenge. Antioxidants (Basel) 10(5):814. https:\/\/doi.org\/10.3390\/antiox10050814","journal-title":"Antioxidants (Basel)"},{"issue":"2","key":"3433_CR5","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1111\/liv.12012","volume":"33","author":"P Recknagel","year":"2013","unstructured":"Recknagel P, Gonnert FA, Halilbasic E, Gajda M, Jbeily N, Lupp A, Rubio I, Claus RA, Kortgen A, Trauner M, Singer M, Bauer M (2013) Mechanisms and functional consequences of liver failure substantially differ between endotoxaemia and faecal peritonitis in rats. Liver Int 33(2):283\u2013293. https:\/\/doi.org\/10.1111\/liv.12012","journal-title":"Liver Int"},{"key":"3433_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1590\/1806-9061-2018-0977","volume":"22","author":"H Hajati","year":"2020","unstructured":"Hajati H, Zaghari M, Oliveira HC (2020) Arthrospira (Spirulina) Platensis can be considered as a probiotic alternative to reduce heat stress in laying Japanese quails. Braz J Poult Sci 22:1\u20138. https:\/\/doi.org\/10.1590\/1806-9061-2018-0977","journal-title":"Braz J Poult Sci"},{"key":"3433_CR7","doi-asserted-by":"publisher","first-page":"748","DOI":"10.1017\/S0007114519000126","volume":"121","author":"TX Pham","year":"2019","unstructured":"Pham TX, Lee Y, Bae M, Hu S, Kang H (2019) Spirulina supplementation in a mouse model of diet-induced liver fibrosis reduced the pro-inflammatory response of splenocytes. Br J Nutr 121:748\u2013755. https:\/\/doi.org\/10.1017\/S0007114519000126","journal-title":"Br J Nutr"},{"issue":"3","key":"3433_CR8","doi-asserted-by":"publisher","first-page":"1853","DOI":"10.1016\/j.sjbs.2020.12.037","volume":"28","author":"P Grover","year":"2021","unstructured":"Grover P, Bhatnagar A, Kumari N, Bhatt AN, Nishad DK, Purkayastha J (2021) C-Phycocyanin-a novel protein from Spirulina platensis- in vivo toxicity, antioxidant and immunomodulatory studies. Saudi J Biol Sci 28(3):1853\u20131859. https:\/\/doi.org\/10.1016\/j.sjbs.2020.12.037","journal-title":"Saudi J Biol Sci"},{"issue":"8","key":"3433_CR9","doi-asserted-by":"publisher","first-page":"1629","DOI":"10.1016\/j.biortech.2006.05.050","volume":"98","author":"ST Silveira","year":"2007","unstructured":"Silveira ST, Burkert JF, Costa JAV, Burkert CAV, Kalil SJ (2007) Optimization of phycocyanin extraction from Spirulina platensis using factorial design. Bioresour Technol 98(8):1629\u20131634. https:\/\/doi.org\/10.1016\/j.biortech.2006.05.050","journal-title":"Bioresour Technol"},{"issue":"1","key":"3433_CR10","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1016\/j.canlet.2006.04.002","volume":"247","author":"H Wang","year":"2007","unstructured":"Wang H, Liu Y, Gao X, Carter CL, Liu ZR (2007) The recombinant beta subunit of C-phycocyanin inhibits cell proliferation and induces apoptosis. Cancer Lett 247(1):150\u2013158. https:\/\/doi.org\/10.1016\/j.canlet.2006.04.002","journal-title":"Cancer Lett"},{"issue":"12","key":"3433_CR11","doi-asserted-by":"publisher","first-page":"967","DOI":"10.2174\/1389200220666191127110857","volume":"20","author":"SM Bannu","year":"2019","unstructured":"Bannu SM, Lomada D, Gulla S, Chandrasekhar T, Reddanna P, Reddy MC (2019) Potential therapeutic applications of C-phycocyanin. Curr Drug Metab 20(12):967\u2013976. https:\/\/doi.org\/10.2174\/1389200220666191127110857","journal-title":"Curr Drug Metab"},{"issue":"1","key":"3433_CR12","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1186\/s12944-020-01298-4","volume":"19","author":"Z Hamedifard","year":"2020","unstructured":"Hamedifard Z, Farrokhian A, Reiner \u017d, Bahmani F, Asemi Z, Ghotbi M, Taghizadeh M (2020) The effects of combined magnesium and zinc supplementation on metabolic status in patients with type 2 diabetes mellitus and coronary heart disease. Lipids Health Dis 19(1):112. https:\/\/doi.org\/10.1186\/s12944-020-01298-4","journal-title":"Lipids Health Dis"},{"issue":"9","key":"3433_CR13","doi-asserted-by":"publisher","first-page":"3929","DOI":"10.18203\/2320-6012.ijrms20173956","volume":"5","author":"J Visalakshy","year":"2017","unstructured":"Visalakshy J, Surendran S, Pillai MPG, Rajendran A, Sherif AA (2017) Could plasma zinc be a predictor for mortality and severity in sepsis syndrome? Int J Res Med Sci 5(9):3929\u20133934. https:\/\/doi.org\/10.18203\/2320-6012.ijrms20173956","journal-title":"Int J Res Med Sci"},{"key":"3433_CR14","doi-asserted-by":"publisher","first-page":"1452S","DOI":"10.1093\/jn\/133.5.1452S","volume":"133","author":"KH Ibs","year":"2003","unstructured":"Ibs KH, Rink L (2003) Zinc-altered immune function. J Nutr 133:1452S-S1456. https:\/\/doi.org\/10.1093\/jn\/133.5.1452S","journal-title":"J Nutr"},{"key":"3433_CR15","doi-asserted-by":"publisher","first-page":"848","DOI":"10.18433\/j34c7n","volume":"16","author":"NM Al-Rasheed","year":"2013","unstructured":"Al-Rasheed NM, Attia HA, Mohamed RA, Al-Rasheed NM, Al-Amin MA (2013) Preventive effects of selenium yeast, chromium picolinate, zinc sulfate and their combination on oxidative stress, inflammation, impaired angiogenesis and atherogenesis in myocardial infarction in rats. J Pharm Pharm Sci 16:848\u2013867. https:\/\/doi.org\/10.18433\/j34c7n","journal-title":"J Pharm Pharm Sci"},{"issue":"1","key":"3433_CR16","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1177\/1753425916677073","volume":"23","author":"HA Ganatra","year":"2017","unstructured":"Ganatra HA, Varisco BM, Harmon K, Lahni P, Opoka A, Wong HR (2017) Zinc supplementation leads to immune modulation and improved survival in a juvenile model of murine sepsis. Innate Immun 23(1):67\u201376. https:\/\/doi.org\/10.1177\/1753425916677073","journal-title":"Innate Immun"},{"issue":"1","key":"3433_CR17","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1080\/1828051X.2020.1786739","volume":"19","author":"M Li","year":"2020","unstructured":"Li M, Zhang Y, Li S (2020) Effects of selenium deficiency on testis development and autophagy in chicks. Ital J Anim Sci 19(1):753\u2013761. https:\/\/doi.org\/10.1080\/1828051X.2020.1786739","journal-title":"Ital J Anim Sci"},{"issue":"5","key":"3433_CR18","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1007\/s10534-018-0128-0","volume":"31","author":"C Cao","year":"2018","unstructured":"Cao C, Li X, Qin L, Luo J, Zhang M, Ou Z, Wang K (2018) High selenium yeast mitigates aluminum-induced cerebral inflammation by increasing oxidative stress and blocking NO production. Biometals 31(5):835\u2013843. https:\/\/doi.org\/10.1007\/s10534-018-0128-0","journal-title":"Biometals"},{"issue":"1","key":"3433_CR19","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1039\/c9mt00216b","volume":"12","author":"J Liu","year":"2020","unstructured":"Liu J, Wang S, Zhang Q, Li X, Xu S (2020) Selenomethionine alleviates LPS-induced chicken myocardial inflammation by regulating the miR-128-3p-p38 MAPK axis and oxidative stress. Metallomics 12(1):54\u201364. https:\/\/doi.org\/10.1039\/c9mt00216b","journal-title":"Metallomics"},{"issue":"1","key":"3433_CR20","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1007\/s12011-017-0979-1","volume":"180","author":"R Fan","year":"2017","unstructured":"Fan R, Yao H, Cao C, Zhao X, Khalid A, Zhao J, Zhang Z, Xu S (2017) Gene silencing of selenoprotein K induces inflammatory response and activates heat shock proteins expression in chicken myoblasts. Biol Trace Elem Res 180(1):135\u2013145. https:\/\/doi.org\/10.1007\/s12011-017-0979-1","journal-title":"Biol Trace Elem Res"},{"issue":"2","key":"3433_CR21","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1007\/s12011-018-1324-z","volume":"186","author":"C Cao","year":"2018","unstructured":"Cao C, Luo J, Li X, Zhang M, Zhang H, Zhang J, Wang K (2018) Selenium-rich yeast protects against aluminum-induced renal inflammation and ionic disturbances. Biol Trace Elem Res 186(2):467\u2013473. https:\/\/doi.org\/10.1007\/s12011-018-1324-z","journal-title":"Biol Trace Elem Res"},{"issue":"1","key":"3433_CR22","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1007\/s12011-019-01841-0","volume":"195","author":"J Qu","year":"2020","unstructured":"Qu J, Wang W, Zhang Q, Li S (2020) Inhibition of lipopolysaccharide-induced inflammation of chicken liver tissue by selenomethionine via TLR4-NF-\u03baB-NLRP3 signaling pathway. Biol Trace Elem Res 195(1):205\u2013214. https:\/\/doi.org\/10.1007\/s12011-019-01841-0","journal-title":"Biol Trace Elem Res"},{"issue":"6","key":"3433_CR23","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1139\/apnm-2018-0519","volume":"44","author":"RU Thoen","year":"2019","unstructured":"Thoen RU, Barther NN, Schemitt E, Bona S, Fernandes S, Coral G, Marroni NP, Tovo C, Guedes RP, Porawski M (2019) Zinc supplementation reduces diet-induced obesity and improves insulin sensitivity in rats. Appl Physiol Nutr Metab 44(6):580\u2013586. https:\/\/doi.org\/10.1139\/apnm-2018-0519","journal-title":"Appl Physiol Nutr Metab"},{"issue":"12","key":"3433_CR24","doi-asserted-by":"publisher","first-page":"4352","DOI":"10.1021\/jf073399k","volume":"56","author":"T Chen","year":"2008","unstructured":"Chen T, Wong YS (2008) In vitro antioxidant and antiproliferative activities of selenium-containing phycocyanin from selenium-enriched Spirulina platensis. J Agric Food Chem 56(12):4352\u20134358. https:\/\/doi.org\/10.1021\/jf073399k","journal-title":"J Agric Food Chem"},{"key":"3433_CR25","doi-asserted-by":"publisher","first-page":"594321","DOI":"10.3389\/fphar.2020.594321","volume":"11","author":"FM Uckun","year":"2020","unstructured":"Uckun FM, Carlson J, Orhan C, Powell J, Pizzimenti NM, Hv W, Ozercan IH, Mand V, Sahin K (2020) Rejuveinix shows a favorable clinical safety profile in human subjects and exhibits potent preclinical protective activity in the lipopolysaccharide-galactosamine mouse model of acute respiratory distress syndrome and multi-organ failure. Front Pharmacol 11:594321. https:\/\/doi.org\/10.3389\/fphar.2020.594321","journal-title":"Front Pharmacol"},{"issue":"5","key":"3433_CR26","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1134\/S0026898419050100","volume":"53","author":"KV Korneev","year":"2019","unstructured":"Korneev KV (2019) Mouse models of sepsis and septic shock. Mol Biol (Mosk) 53(5):799\u2013814. https:\/\/doi.org\/10.1134\/S0026898419050100","journal-title":"Mol Biol (Mosk)"},{"key":"3433_CR27","doi-asserted-by":"publisher","first-page":"100081","DOI":"10.1016\/j.fochms.2022.100081","volume":"4","author":"K Sahin","year":"2022","unstructured":"Sahin K, Orhan C, Kucuk O, Tuzcu M, Sahin N, Ozercan IH, Sylla S, Ojalvo SP, Komorowski JR (2022) Effects of magnesium picolinate, zinc picolinate, and selenomethionine co-supplementation on reproductive hormones, and glucose and lipid metabolism-related protein expressions in male rats fed a high-fat diet. Food Chem: Mole Sci 4:100081. https:\/\/doi.org\/10.1016\/j.fochms.2022.100081","journal-title":"Food Chem: Mole Sci"},{"issue":"19","key":"3433_CR28","doi-asserted-by":"publisher","first-page":"2353","DOI":"10.1016\/j.lfs.2004.06.004","volume":"75","author":"S Benedetti","year":"2004","unstructured":"Benedetti S, Benvenuti F, Pagliarani S, Francogli S, Scoglio S, Canestrari F (2004) Antioxidant properties of a novel phycocyanin extract from the blue-green alga Aphanizomenon flos-aquae. Life Sci 75(19):2353\u20132362. https:\/\/doi.org\/10.1016\/j.lfs.2004.06.004","journal-title":"Life Sci"},{"issue":"3","key":"3433_CR29","doi-asserted-by":"publisher","first-page":"756","DOI":"10.3390\/ani11030756","volume":"11","author":"F Hassan","year":"2021","unstructured":"Hassan F, Mobarez S, Mohamed M, Attia Y, Mekawy A, Mahrose K (2021) Zinc and\/or selenium enriched spirulina as antioxidants in growing rabbit diets to alleviate the deleterious impacts of heat stress during summer season. Animals (Basel) 11(3):756. https:\/\/doi.org\/10.3390\/ani11030756","journal-title":"Animals (Basel)"},{"issue":"14","key":"3433_CR30","doi-asserted-by":"publisher","first-page":"e14933","DOI":"10.14814\/phy2.14933","volume":"9","author":"T Castel","year":"2021","unstructured":"Castel T, Theron M, Pichavant-Rafini K, Guernec A, Joublin-Delavat A, Gueguen B, Leon K (2021) Can selenium-enriched spirulina supplementation ameliorate sepsis outcomes in selenium-deficient animals? Physiol Rep 9(14):e14933. https:\/\/doi.org\/10.14814\/phy2.14933","journal-title":"Physiol Rep"},{"key":"3433_CR31","doi-asserted-by":"publisher","first-page":"3247528","DOI":"10.1155\/2017\/3247528","volume":"2017","author":"A Finamore","year":"2017","unstructured":"Finamore A, Palmery M, Bensehaila S, Peluso I (2017) Antioxidant, immunomodulating, and microbial-modulating activities of the sustainable and ecofriendly spirulina. Oxid Med Cell Longev 2017:3247528. https:\/\/doi.org\/10.1155\/2017\/3247528","journal-title":"Oxid Med Cell Longev"},{"key":"3433_CR32","doi-asserted-by":"publisher","first-page":"215","DOI":"10.17179\/excli2017-1016","volume":"17","author":"M Gargouri","year":"2018","unstructured":"Gargouri M, Soussi A, Akrouti A, Magn\u00e9 C, El Feki A (2018) Ameliorative effects of Spirulina platensis against lead-induced nephrotoxicity in newborn rats: modulation of oxidative stress and histopathological changes. EXCLI J 17:215\u2013232. https:\/\/doi.org\/10.17179\/excli2017-1016","journal-title":"EXCLI J"},{"key":"3433_CR33","doi-asserted-by":"publisher","first-page":"375","DOI":"10.2147\/DMSO.S172104","volume":"11","author":"F Nasirian","year":"2018","unstructured":"Nasirian F, Dadkhah M, Moradi-kor N, Obeidavi Z (2018) Effects of Spirulina platensis microalgae on antioxidant and anti-inflammatory factors in diabetic rats. Diabetes Metabo Syndr Obes 11:375\u2013380. https:\/\/doi.org\/10.2147\/DMSO.S172104","journal-title":"Diabetes Metabo Syndr Obes"},{"key":"3433_CR34","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.biopha.2015.12.003","volume":"77","author":"M Abdel-Daim","year":"2016","unstructured":"Abdel-Daim M, El-Bialy BE, Rahman HGA, Radi AM, Hefny HA, Hassan AM (2016) Antagonistic effects of Spirulina platensis against sub-acute deltamethrin toxicity in mice: biochemical and histopathological studies. Biomed Pharmacother 77:79\u201385. https:\/\/doi.org\/10.1016\/j.biopha.2015.12.003","journal-title":"Biomed Pharmacother"},{"key":"3433_CR35","doi-asserted-by":"publisher","first-page":"539","DOI":"10.3109\/13880209.2012.747545","volume":"51","author":"Y Ou","year":"2013","unstructured":"Ou Y, Lin L, Yang X, Pan Q, Cheng X (2013) Antidiabetic potential of phycocyanin: effects on KKAy mice. Pharm Biol 51:539\u2013544. https:\/\/doi.org\/10.3109\/13880209.2012.747545","journal-title":"Pharm Biol"},{"key":"3433_CR36","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1152\/physrev.00039.2013","volume":"94","author":"VM Labunskyy","year":"2014","unstructured":"Labunskyy VM, Hatfield DL, Vadim N, Gladyshe VN (2014) Selenoproteins: molecular pathways and physiological roles. Physiol Rev 94:739\u2013777. https:\/\/doi.org\/10.1152\/physrev.00039.2013","journal-title":"Physiol Rev"},{"key":"3433_CR37","doi-asserted-by":"publisher","first-page":"164","DOI":"10.3390\/antiox8060164","volume":"8","author":"AS Prasad","year":"2019","unstructured":"Prasad AS, Bao B (2019) Molecular mechanisms of zinc as a pro-antioxidant mediator: clinical therapeutic implications. Antioxidants 8:164. https:\/\/doi.org\/10.3390\/antiox8060164","journal-title":"Antioxidants"},{"issue":"5S","key":"3433_CR38","doi-asserted-by":"publisher","first-page":"1447S","DOI":"10.1093\/jn\/130.5.1447S","volume":"130","author":"SR Powell","year":"2000","unstructured":"Powell SR (2000) The antioxidant properties of zinc. J Nutr 130(5S):1447S-S1454. https:\/\/doi.org\/10.1093\/jn\/130.5.1447S","journal-title":"J Nutr"},{"issue":"5","key":"3433_CR39","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1111\/j.0959-9673.2004.00392.x","volume":"85","author":"EM Alissa","year":"2004","unstructured":"Alissa EM, Bahijri SM, Lamb DJ, Gordon A, Ferns GAA (2004) The effects of coadministration of dietary copper and zinc supplements on atherosclerosis, antioxidant enzymes and indices of lipid peroxidation in the cholesterol-fed rabbit. Int J Exp Pathol 85(5):265\u2013275. https:\/\/doi.org\/10.1111\/j.0959-9673.2004.00392.x","journal-title":"Int J Exp Pathol"},{"issue":"1","key":"3433_CR40","first-page":"46","volume":"13","author":"MT Utomo","year":"2020","unstructured":"Utomo MT, Sudarmo SM, Sudiana K (2020) Zinc supplementation in cytokine regulation during LPS-induced sepsis in rodent. J Int Dent Med Res 13(1):46\u201350","journal-title":"J Int Dent Med Res"},{"issue":"8","key":"3433_CR41","doi-asserted-by":"publisher","first-page":"620","DOI":"10.3390\/jmse8080620","volume":"8","author":"I Michalak","year":"2020","unstructured":"Michalak I, Mahrose KM (2020) Seaweeds, intact and processed, as a valuable component of poultry feed. J Mar Sci Eng 8(8):620. https:\/\/doi.org\/10.3390\/jmse8080620","journal-title":"J Mar Sci Eng"},{"issue":"2","key":"3433_CR42","doi-asserted-by":"publisher","first-page":"73","DOI":"10.9734\/JPRI\/2020\/v32i230407","volume":"32","author":"GA Gabr","year":"2020","unstructured":"Gabr GA, El-Sayed SM, Hikal MS (2020) Antioxidant activities of phycocyanin: a bioactive compound from Spirulina platensis. J Pharm Res Int 32(2):73\u201385. https:\/\/doi.org\/10.9734\/JPRI\/2020\/v32i230407","journal-title":"J Pharm Res Int"},{"key":"3433_CR43","doi-asserted-by":"publisher","first-page":"124427","DOI":"10.1016\/j.chemosphere.2019.124427","volume":"237","author":"X Hu","year":"2019","unstructured":"Hu X, Chi Q, Liu Q, Wang D, Zhang Y, Li S (2019) Atmospheric H2S triggers immune damage by activating the TLR-7\/MyD88\/NF-kB pathway and NLRP3 inflammasome in broiler thymus. Chemosphere 237:124427. https:\/\/doi.org\/10.1016\/j.chemosphere.2019.124427","journal-title":"Chemosphere"},{"key":"3433_CR44","doi-asserted-by":"publisher","first-page":"G768","DOI":"10.1152\/ajpgi.00179.2015","volume":"309","author":"I Wessels","year":"2015","unstructured":"Wessels I, Cousins RJ (2015) Zinc dyshomeostasis during polymicrobial sepsis in mice involves zinc transporter Zip14 and can be overcome by zinc supplementation. Am J Physiol Gastrointest Liver Physiol 309:G768\u2013G778. https:\/\/doi.org\/10.1152\/ajpgi.00179.2015","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"3433_CR45","doi-asserted-by":"publisher","first-page":"111125","DOI":"10.1016\/j.biopha.2020.111125","volume":"134","author":"A Shalihat","year":"2021","unstructured":"Shalihat A, Hasanah AN, Mutakin LR, Budiman A, Gozali D (2021) The role of selenium in cell survival and its correlation with protective effects against cardiovascular disease: a literature review. Biomed Pharmacother 134:111125. https:\/\/doi.org\/10.1016\/j.biopha.2020.111125","journal-title":"Biomed Pharmacother"},{"issue":"1","key":"3433_CR46","doi-asserted-by":"publisher","first-page":"e54431","DOI":"10.1371\/journal.pone.0054431","volume":"8","author":"TS Huang","year":"2013","unstructured":"Huang TS, Shyu YC, Chen HY, Lin LM, Lo CY, Yuan SS, Chen PJ (2013) Effect of parenteral selenium supplementation in critically ill patients: a systematic review and metaanalysis. PLoS ONE 8(1):e54431. https:\/\/doi.org\/10.1371\/journal.pone.0054431","journal-title":"PLoS ONE"},{"issue":"1","key":"3433_CR47","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1016\/j.jcrc.2013.08.017","volume":"29","author":"F Landucci","year":"2014","unstructured":"Landucci F, Mancinelli P, De Gaudio AR (2014) Selenium supplementation in critically ill patients: a systematic review and meta-analysis. J Crit Care 29(1):150\u2013156. https:\/\/doi.org\/10.1016\/j.jcrc.2013.08.017","journal-title":"J Crit Care"},{"key":"3433_CR48","doi-asserted-by":"publisher","first-page":"878","DOI":"10.1002\/jcb.25767","volume":"118","author":"S Nithiananthan","year":"2017","unstructured":"Nithiananthan S, Crawford A, Knock JC, Lambert DW, Whawell SA (2017) Physiological fluid flow moderates fibroblast responses to TGF-\u03b21. J Cell Biochem 118:878\u2013890. https:\/\/doi.org\/10.1002\/jcb.25767","journal-title":"J Cell Biochem"},{"key":"3433_CR49","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1016\/j.biopha.2018.10.118","volume":"109","author":"YI Mahmoud","year":"2019","unstructured":"Mahmoud YI, Abd El-Ghffar EA (2019) Spirulina ameliorates aspirin-induced gastric ulcer in albino mice by alleviating oxidative stress and inflammation. Biomed Pharmacother 109:314\u2013321. https:\/\/doi.org\/10.1016\/j.biopha.2018.10.118","journal-title":"Biomed Pharmacother"},{"issue":"6","key":"3433_CR50","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1007\/s10534-018-0150-2","volume":"31","author":"J Luo","year":"2018","unstructured":"Luo J, Li X, Li X, He Y, Zhang M, Cao C, Wang K (2018) Selenium-rich yeast protects against aluminum-induced peroxidation of lipide and inflammation in mice liver. Biometals 31(6):1051\u20131059. https:\/\/doi.org\/10.1007\/s10534-018-0150-2","journal-title":"Biometals"},{"key":"3433_CR51","doi-asserted-by":"publisher","first-page":"1390","DOI":"10.1039\/c8mt00142a","volume":"10","author":"J Wang","year":"2018","unstructured":"Wang J, Liu Z, He X, Lian S, Liang J, Yu D, Sun D, Wu R (2018) Selenium deficiency induces duodenal villi cell apoptosis via an oxidative stress-induced mitochondrial apoptosis pathway and an inflammatory signaling-induced death receptor pathway. Metallomics 10:1390\u20131400. https:\/\/doi.org\/10.1039\/c8mt00142a","journal-title":"Metallomics"},{"issue":"5","key":"3433_CR52","doi-asserted-by":"publisher","first-page":"1885","DOI":"10.1007\/s12011-020-02295-5","volume":"199","author":"X Wang","year":"2021","unstructured":"Wang X, Yang B, Cao HL, Wang RY, Lu ZY, Chi RF, Li B (2021) Selenium supplementation protects against lipopolysaccharide-induced heart injury via sting pathway in mice. Biol Trace Elem Res 199(5):1885\u20131892. https:\/\/doi.org\/10.1007\/s12011-020-02295-5","journal-title":"Biol Trace Elem Res"},{"issue":"4","key":"3433_CR53","doi-asserted-by":"publisher","first-page":"1380","DOI":"10.1097\/CCM.0b013e31819cefe4","volume":"37","author":"DL Knoell","year":"2009","unstructured":"Knoell DL, Julian MW, Bao S, Besecker B, Macre JE, Leikauf GD, DiSilvestro RA, Crouser ED (2009) Zinc deficiency increases organ damage and mortality in a murine model of polymicrobial sepsis. Crit Care Med 37(4):1380\u20131388. https:\/\/doi.org\/10.1097\/CCM.0b013e31819cefe4","journal-title":"Crit Care Med"}],"container-title":["Biological Trace Element Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12011-022-03433-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12011-022-03433-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12011-022-03433-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,4]],"date-time":"2023-02-04T03:24:08Z","timestamp":1675481048000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12011-022-03433-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,29]]},"references-count":53,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["3433"],"URL":"https:\/\/doi.org\/10.1007\/s12011-022-03433-x","relation":{},"ISSN":["0163-4984","1559-0720"],"issn-type":[{"value":"0163-4984","type":"print"},{"value":"1559-0720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,29]]},"assertion":[{"value":"27 May 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 September 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 September 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}