{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T06:43:54Z","timestamp":1782801834256,"version":"3.54.5"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T00:00:00Z","timestamp":1774224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T00:00:00Z","timestamp":1774224000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biol Trace Elem Res"],"DOI":"10.1007\/s12011-026-05042-4","type":"journal-article","created":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T23:11:38Z","timestamp":1774307498000},"page":"5432-5437","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Selenium\u2019s Emergence from the Pool of Potentially Essential Trace Elements"],"prefix":"10.1007","volume":"204","author":[{"given":"Roger A.","family":"Sunde","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,23]]},"reference":[{"key":"5042_CR1","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1093\/jn\/89.1.24","volume":"89","author":"FH Nielsen","year":"1966","unstructured":"Nielsen FH, Sunde ML, Hoekstra WG (1966) Effect of dietary amino acid source on the zinc-deficiency syndrome in the chick. J Nutr 89:24\u201334. https:\/\/doi.org\/10.1093\/jn\/89.1.24","journal-title":"J Nutr"},{"key":"5042_CR2","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1093\/jn\/89.1.35","volume":"89","author":"FH Nielsen","year":"1966","unstructured":"Nielsen FH, Sunde ML, Hoekstra WG (1966) Effect of some dietary synthetic and natural chelating agents on the zinc-deficiency syndrome in the chick. J Nutr 89:35\u201342. https:\/\/doi.org\/10.1093\/jn\/89.1.35","journal-title":"J Nutr"},{"key":"5042_CR3","doi-asserted-by":"publisher","first-page":"1106","DOI":"10.3181\/00379727-124-31937","volume":"124","author":"FH Nielsen","year":"1967","unstructured":"Nielsen FH, Sunde ML, Hoekstra WG (1967) Effect of histamine, histidine, and some related compounds on the zinc-deficient chick. Proc Soc Exp Biol Med 124:1106\u20131110. https:\/\/doi.org\/10.3181\/00379727-124-31937","journal-title":"Proc Soc Exp Biol Med"},{"key":"5042_CR4","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1093\/jn\/94.4.527","volume":"94","author":"FH Nielsen","year":"1968","unstructured":"Nielsen FH, Sunde ML, Hoekstra WG (1968) Alleviation of the leg abnormality in zinc-deficient chicks by histamine and by various anti-arthritic agents. J Nutr 94:527\u2013\u200933. https:\/\/doi.org\/10.1093\/jn\/94.4.527","journal-title":"J Nutr"},{"key":"5042_CR5","doi-asserted-by":"publisher","first-page":"845","DOI":"10.3181\/00379727-134-34896","volume":"134","author":"FH Nielsen","year":"1970","unstructured":"Nielsen FH, Sauberlich HE (1970) Evidence of a possible requirement for nickel by the chick. Proc Soc Exp Biol Med 134:845\u2013849. https:\/\/doi.org\/10.3181\/00379727-134-34896","journal-title":"Proc Soc Exp Biol Med"},{"key":"5042_CR6","doi-asserted-by":"publisher","first-page":"1620","DOI":"10.1093\/jn\/105.12.1620","volume":"105","author":"FH Nielsen","year":"1975","unstructured":"Nielsen FH, Myron DR, Givand SH, Zimmerman TJ, Ollerich DA (1975) Nickel deficiency in rats. J Nutr 105:1620\u20131630. https:\/\/doi.org\/10.1093\/jn\/105.12.1620","journal-title":"J Nutr"},{"key":"5042_CR7","first-page":"502","volume":"29","author":"FH Nielsen","year":"1979","unstructured":"Nielsen FH, Bailey B (1979) The fabrication of plastic cages for suspension in mass air flow racks. Lab Anim Sci 29:502\u2013506","journal-title":"Lab Anim Sci"},{"key":"5042_CR8","doi-asserted-by":"publisher","first-page":"173","DOI":"10.3945\/jn.108.092692","volume":"139","author":"HH Sandstead","year":"2009","unstructured":"Sandstead HH, Nielsen FH (2009) The origin and evolution of the Grand Forks Human Nutrition Research Center, 1970-90. J Nutr 139:173\u2013177. https:\/\/doi.org\/10.3945\/jn.108.092692","journal-title":"J Nutr"},{"key":"5042_CR9","volume-title":"Dietary Reference Allowances","author":"Food and Nutrition Board","year":"1968","unstructured":"Food and Nutrition Board (1968) Dietary Reference Allowances, 7th edn. National Academy, Washington, D.C.","edition":"7"},{"key":"5042_CR10","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/S0002-8223(21)12593-3","volume":"54","author":"WH Sebrell Jr","year":"1969","unstructured":"Sebrell WH Jr (1969) Recommended dietary allowances\u20131968 revision. J Am Diet Assoc 54:103-8","journal-title":"J Am Diet Assoc"},{"key":"5042_CR11","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-41283-2","volume-title":"Selenium. Its molecular biology and role in human health","author":"DL Hatfield","year":"2016","unstructured":"Hatfield DL, Schweizer U, Tsuji PA, Gladyshev VN (2016) Selenium. Its molecular biology and role in human health, 4th edn. Springer, New York","edition":"4"},{"key":"5042_CR12","doi-asserted-by":"publisher","first-page":"24036","DOI":"10.1074\/jbc.m116.756155","volume":"291","author":"VN Gladyshev","year":"2016","unstructured":"Gladyshev VN, Arner ES, Berry MJ, Brigelius-Flohe R, Bruford EA, Burk RF, Carlson BA, Castellano S, Chavatte L et al (2016) Selenoprotein gene nomenclature. J Biol Chem 291:24036\u201324040. https:\/\/doi.org\/10.1074\/jbc.m116.756155","journal-title":"J Biol Chem"},{"key":"5042_CR13","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.3945\/an.116.012872","volume":"7","author":"RA Sunde","year":"2016","unstructured":"Sunde RA, Li JL, Taylor RM (2016) Insights for setting of nutrient requirements, gleaned by comparison of selenium status biomarkers in turkeys and chickens versus rats, mice, and lambs. Adv Nutr 7:1129\u20131138. https:\/\/doi.org\/10.3945\/an.116.012872","journal-title":"Adv Nutr"},{"key":"5042_CR14","unstructured":"Lei XG, Rayman MP, Sunde RA (2025) Selenium. In: Tucker KL, Ross CA, Jensen GL, Torger-Decker R, Duggan CP (eds). Modern Nutrition in Health and Disease (MNHD). 12 ed. pp. 233\u2009\u2013\u200956"},{"key":"5042_CR15","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1146\/annurev-nutr-062320-121834","volume":"42","author":"XG Lei Jr.","year":"2022","unstructured":"Lei XG, Combs GF Jr., Sunde RA, Caton JS, Arthington JD, Vatamaniuk MZ (2022) Dietary Selenium Across Species. Annu Rev Nutr 42:337\u2009\u2013\u200975. https:\/\/doi.org\/10.1146\/annurev-nutr-062320-121834","journal-title":"Annu Rev Nutr"},{"key":"5042_CR16","doi-asserted-by":"publisher","DOI":"10.1201\/9781482273106","volume-title":"Handbook of Nutritionally Essential Mineral Elements","author":"BL O\u2019Dell","year":"1997","unstructured":"O\u2019Dell BL, Sunde RA (1997) Handbook of Nutritionally Essential Mineral Elements. Marcel Dekker, Inc., New York"},{"key":"5042_CR17","first-page":"5","volume":"1","author":"GC Cotzias","year":"1967","unstructured":"Cotzias GC (1967) Importance of trace substances in environmental health as exemplified by manganese. Proc Univ Missouri\u2019s 1st Annual Conf Trace Substances Environ Health 1:5\u201319","journal-title":"Proc Univ Missouri\u2019s 1st Annual Conf Trace Substances Environ Health"},{"key":"5042_CR18","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1152\/physrev.1943.23.4.305","volume":"23","author":"AL Moxon","year":"1943","unstructured":"Moxon AL, Rhian MA (1943) Selenium poisoning. Physiol Rev 23:305\u2013337","journal-title":"Physiol Rev"},{"key":"5042_CR19","first-page":"230","volume":"3","author":"AA Nelson","year":"1943","unstructured":"Nelson AA, Fitzhugh OG, Calvery HO (1943) Liver tumors following cirrhosis caused by selenium in rat. Cancer Res 3:230\u2013236","journal-title":"Cancer Res"},{"key":"5042_CR20","first-page":"153","volume-title":"Selenium in Biomedicine","author":"JR Harr","year":"1967","unstructured":"Harr JR, Bone JF, Tinsley IJ, Weswig PH, Yamamoto RS (1967) Selenium toxicity in rats II. Histopathology. In: Muth OH, Oldfield JE, Weswig PH (eds) Selenium in Biomedicine. AVI Publishing Co., Westport, pp 153\u2013178"},{"key":"5042_CR21","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/s0006-3061(00)80164-7","volume":"8","author":"GN Schrauzer","year":"1978","unstructured":"Schrauzer GN, White DA (1978) Selenium in human nutrition: dietary intakes and effects of supplementation. Bioinorg Chem. https:\/\/doi.org\/10.1016\/s0006-3061(00)80164-7","journal-title":"Bioinorg Chem"},{"key":"5042_CR22","doi-asserted-by":"publisher","first-page":"3292","DOI":"10.1021\/ja01569a087","volume":"79","author":"K Schwarz","year":"1957","unstructured":"Schwarz K, Foltz CM (1957) Selenium as an integral part of factor 3 against dietary necrotic liver degeneration. J Am Chem Soc 79:3292\u20133293","journal-title":"J Am Chem Soc"},{"key":"5042_CR23","first-page":"1155","volume":"36","author":"ML Scott","year":"1957","unstructured":"Scott ML, Bieri JG, Briggs GM, Schwarz K (1957) Prevention of exudative diathesis by Factor 3 in chicks on vitamin E-deficient Torula yeast diets. Poult Sci 36:1155","journal-title":"Poult Sci"},{"key":"5042_CR24","volume-title":"Selenium in Nutrition","author":"National Research Council","year":"1983","unstructured":"National Research Council (1983) Selenium in Nutrition. National Academy, Washington, DC"},{"key":"5042_CR25","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1093\/jn\/100.7.797","volume":"100","author":"JN Thompson","year":"1970","unstructured":"Thompson JN, Scott ML (1970) Impaired lipid and vitamin E absorption related to atrophy of the pancreas in selenium-deficient chicks. J Nutr 100:797\u2013809. https:\/\/doi.org\/10.1093\/jn\/100.7.797","journal-title":"J Nutr"},{"key":"5042_CR26","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1093\/jn\/100.7.797","volume":"51","author":"DE Ullrey","year":"1980","unstructured":"Ullrey DE (1980) Regulation of essential nutrient additions to animal diets (selenium -- a model case). J Anim Sci 51:645\u2009\u2013\u200951. https:\/\/doi.org\/10.1093\/jn\/100.7.797","journal-title":"J Anim Sci"},{"key":"5042_CR27","first-page":"2083","volume":"34","author":"WG Hoekstra","year":"1975","unstructured":"Hoekstra WG (1975) Biochemical function of selenium and its relation to vitamin E. Fed Proc 34:2083\u20132089","journal-title":"Fed Proc"},{"key":"5042_CR28","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1038\/newbio231223a0","volume":"231","author":"JT Rotruck","year":"1971","unstructured":"Rotruck JT, Hoekstra WG, Pope AL (1971) Glucose-dependent protection by dietary selenium against haemolysis of rat erythrocytes in vitro. Nat New Biol 231:223\u2013224","journal-title":"Nat New Biol"},{"key":"5042_CR29","first-page":"691","volume":"31","author":"JT Rotruck","year":"1972","unstructured":"Rotruck JT, Hoekstra WG, Pope AL, Ganther H, Swanson A, Hafeman DG (1972) Relationship of selenium to GSH peroxidase. Fed Proc 31:691 [Abst.]","journal-title":"Fed Proc"},{"key":"5042_CR30","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1093\/jn\/102.5.689","volume":"102","author":"JT Rotruck","year":"1972","unstructured":"Rotruck JT, Pope AL, Ganther HE, Hoekstra WG (1972) Prevention of oxidative damage to rat erythrocytes by dietary selenium. J Nutr 102:689\u201396. https:\/\/doi.org\/10.1093\/jn\/102.5.689","journal-title":"J Nutr"},{"key":"5042_CR31","first-page":"885","volume":"32","author":"WG Hoekstra","year":"1973","unstructured":"Hoekstra WG, Hafeman DG, Oh SH, Sunde RA, Ganther HE (1973) Effect of dietary selenium on liver and erythrocyte glutathione peroxidase in the rat. Fed Proc 32:885 [Abst.]","journal-title":"Fed Proc"},{"key":"5042_CR32","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1126\/science.179.4073.588","volume":"179","author":"JT Rotruck","year":"1973","unstructured":"Rotruck JT, Pope AL, Ganther HE, Swanson AB, Hafeman DG, Hoekstra WG (1973) Selenium: biochemical role as a component of glutathione peroxidase. Science 179:588\u2013590. https:\/\/doi.org\/10.1126\/science.179.4073.588","journal-title":"Science"},{"key":"5042_CR33","doi-asserted-by":"publisher","first-page":"1825","DOI":"10.1021\/bi00706a008","volume":"13","author":"SH Oh","year":"1974","unstructured":"Oh SH, Ganther HE, Hoekstra WG (1974) Selenium as a component of glutathione peroxidase isolated from ovine erythrocytes. Biochem 13:1825\u20131829. https:\/\/doi.org\/10.1021\/bi00706a008","journal-title":"Biochem"},{"key":"5042_CR34","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1093\/jn\/104.5.580","volume":"104","author":"DG Hafeman","year":"1974","unstructured":"Hafeman DG, Sunde RA, Hoekstra WG (1974) Effect of dietary selenium on erythrocyte and liver glutathione peroxidase in the rat. J Nutr 104:580\u2013587. https:\/\/doi.org\/10.1093\/jn\/104.5.580","journal-title":"J Nutr"},{"key":"5042_CR35","doi-asserted-by":"publisher","first-page":"e0151665","DOI":"10.1371\/journal.pone.0151665","volume":"11","author":"RM Taylor","year":"2016","unstructured":"Taylor RM, Sunde RA (2016) Selenoprotein transcript level and enzyme activity as biomarkers for selenium status and selenium requirements of turkeys (Meleagris gallopavo). PLoS ONE 11:e0151665. https:\/\/doi.org\/10.1371\/journal.pone.0151665","journal-title":"PLoS ONE"},{"key":"5042_CR36","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.1038\/ncb3064","volume":"16","author":"JP Friedmann Angeli","year":"2014","unstructured":"Friedmann Angeli JP, Schneider M, Proneth B, Tyurina YY, Tyurin VA, Hammond VJ, Herbach N, Aichler M, Walch A et al (2014) Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nat Cell Biol 16:1180\u20131191. https:\/\/doi.org\/10.1038\/ncb3064","journal-title":"Nat Cell Biol"},{"key":"5042_CR37","first-page":"1143","volume-title":"Biochemical, Physiological, and Molecular Aspects of Human Nutrition","author":"FH Nielsen","year":"2006","unstructured":"Nielsen FH (2006) The ultra trace elements. In: Stipanuk MH (ed) Biochemical, Physiological, and Molecular Aspects of Human Nutrition, 2nd edn. W.B. Sanders, New York, NY, pp 1143\u20131163","edition":"2"},{"key":"5042_CR38","doi-asserted-by":"publisher","DOI":"10.1201\/9781482273106","volume-title":"Handbook of Nutritionally Essential Mineral Elements","author":"BL O\u2019Dell","year":"1997","unstructured":"O\u2019Dell BL, Sunde RA (1997) Handbook of Nutritionally Essential Mineral Elements. Marcel Dekker, Inc., New York"},{"key":"5042_CR39","first-page":"265","volume-title":"Modern Nutrition in Health and Disease (MNHD)","author":"CD Eckhert","year":"2025","unstructured":"Eckhert CD (2025) Trace Elements. In: Tucker KL, Ross CA, Jensen GL, Torger-Decker R, Duggan CP (eds) Modern Nutrition in Health and Disease (MNHD). Jones and Bartlett, Burlington, pp. 265\u201379"},{"key":"5042_CR40","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1111\/j.1439-0396.1975.tb01118.x","volume":"36","author":"A Schnegg","year":"1975","unstructured":"Schnegg A, Kirchgessner M (1975) [The essentiality of nickel for animal growth]. Z Tierphysiol Tierernahr Futtermittelkd 36:63\u201374.","journal-title":"Z Tierphysiol Tierernahr Futtermittelkd"},{"key":"5042_CR41","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1093\/advances\/nmaa154","volume":"12","author":"FH Nielsen","year":"2021","unstructured":"Nielsen FH (2021) Nickel. Adv Nutr 12:281\u2013282. https:\/\/doi.org\/10.1093\/advances\/nmaa154","journal-title":"Adv Nutr"},{"key":"5042_CR42","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1093\/advances\/nmz110","volume":"11","author":"FH Nielsen","year":"2020","unstructured":"Nielsen FH, Eckhert CD (2020) Boron. Adv Nutr 11:461\u2013462. https:\/\/doi.org\/10.1093\/advances\/nmz110","journal-title":"Adv Nutr"},{"key":"5042_CR43","doi-asserted-by":"publisher","first-page":"2488","DOI":"10.1093\/jn\/128.12.2488","volume":"128","author":"CD Eckhert","year":"1998","unstructured":"Eckhert CD (1998) Boron stimulates embryonic trout growth. J Nutr 128:2488\u20132493. https:\/\/doi.org\/10.1093\/jn\/128.12.2488","journal-title":"J Nutr"},{"key":"5042_CR44","doi-asserted-by":"publisher","first-page":"16592","DOI":"10.1073\/pnas.0605141103","volume":"103","author":"H Iwai","year":"2006","unstructured":"Iwai H, Hokura A, Oishi M, Chida H, Ishii T, Sakai S, Satoh S (2006) The gene responsible for borate cross-linking of pectin Rhamnogalacturonan-II is required for plant reproductive tissue development and fertilization. Proc Natl Acad Sci U S A 103:16592\u201316597. https:\/\/doi.org\/10.1073\/pnas.0605141103","journal-title":"Proc Natl Acad Sci U S A"},{"key":"5042_CR45","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1016\/j.tplants.2008.05.007","volume":"13","author":"J Takano","year":"2008","unstructured":"Takano J, Miwa K, Fujiwara T (2008) Boron transport mechanisms: collaboration of channels and transporters. Trends Plant Sci 13:451\u2013457. https:\/\/doi.org\/10.1016\/j.tplants.2008.05.007","journal-title":"Trends Plant Sci"},{"key":"5042_CR46","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1038\/s41586-025-09335-x","volume":"645","author":"L Aron","year":"2025","unstructured":"Aron L, Ngian ZK, Qiu C, Choi J, Liang M, Drake DM, Hamplova SE, Lacey EK, Roche P et al (2025) Lithium deficiency and the onset of Alzheimer\u2019s disease. Nature 645:712\u2013721. https:\/\/doi.org\/10.1038\/s41586-025-09335-x","journal-title":"Nature"},{"key":"5042_CR47","doi-asserted-by":"publisher","first-page":"463","DOI":"10.3389\/fpls.2016.00463","volume":"7","author":"G Guerriero","year":"2016","unstructured":"Guerriero G, Hausman JF, Legay S (2016) Silicon and the Plant Extracellular Matrix. Front Plant Sci 7:463. https:\/\/doi.org\/10.3389\/fpls.2016.00463","journal-title":"Front Plant Sci"},{"key":"5042_CR48","doi-asserted-by":"publisher","first-page":"918","DOI":"10.1111\/j.1365-2958.2008.06208.x","volume":"68","author":"EE Regulski","year":"2008","unstructured":"Regulski EE, Moy RH, Weinberg Z, Barrick JE, Yao Z, Ruzzo WL, Breaker RR (2008) A widespread riboswitch candidate that controls bacterial genes involved in molybdenum cofactor and tungsten cofactor metabolism. Mol Microbiol 68:918\u2009\u2013\u200932. https:\/\/doi.org\/10.1111\/j.1365-2958.2008.06208.x","journal-title":"Mol Microbiol"},{"key":"5042_CR49","first-page":"1482","volume":"29","author":"W Mertz","year":"1970","unstructured":"Mertz W (1970) Some aspects of nutritional trace element research. Fed Proc 29:1482\u20131488","journal-title":"Fed Proc"},{"key":"5042_CR50","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.taap.2004.10.018","volume":"206","author":"KT Suzuki","year":"2005","unstructured":"Suzuki KT, Kurasaki K, Okazaki N, Ogra Y (2005) Selenosugar and trimethylselenonium among urinary Se metabolites: dose- and age-related changes. Toxicol Appl Pharmacol 206:1\u20138. https:\/\/doi.org\/10.1016\/j.taap.2004.10.018","journal-title":"Toxicol Appl Pharmacol"},{"key":"5042_CR51","doi-asserted-by":"publisher","first-page":"mfad066","DOI":"10.1093\/mtomcs\/mfad066","volume":"15","author":"K Bierla","year":"2023","unstructured":"Bierla K, Szpunar J, Lobinski R, Sunde RA (2023) Effect of graded levels of selenium supplementation as selenite on expression of selenosugars, selenocysteine, and other selenometabolites in rat liver. Metallomics 15:mfad066. https:\/\/doi.org\/10.1093\/mtomcs\/mfad066","journal-title":"Metallomics"}],"container-title":["Biological Trace Element Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12011-026-05042-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12011-026-05042-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12011-026-05042-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T05:50:28Z","timestamp":1782798628000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12011-026-05042-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,23]]},"references-count":51,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2026,7]]}},"alternative-id":["5042"],"URL":"https:\/\/doi.org\/10.1007\/s12011-026-05042-4","relation":{},"ISSN":["1559-0720"],"issn-type":[{"value":"1559-0720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,23]]},"assertion":[{"value":"28 January 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}