{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T15:33:28Z","timestamp":1790609608096,"version":"4.1.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2014,10,9]],"date-time":"2014-10-09T00:00:00Z","timestamp":1412812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cardiovasc Toxicol"],"published-print":{"date-parts":[[2015,7]]},"DOI":"10.1007\/s12012-014-9278-7","type":"journal-article","created":{"date-parts":[[2014,10,8]],"date-time":"2014-10-08T15:46:43Z","timestamp":1412783203000},"page":"203-209","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Epigenetic Regulation of Cardiac Myofibril Gene Expression During Heart Development"],"prefix":"10.1007","volume":"15","author":[{"given":"Weian","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingjuan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changlong","family":"Nan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xupei","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,10,9]]},"reference":[{"key":"9278_CR1","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1146\/annurev.ph.58.030196.002311","volume":"58","author":"LS Tobacman","year":"1996","unstructured":"Tobacman, L. S. (1996). Thin filament-mediated regulation of cardiac contraction. Annual Review of Physiology, 58, 447\u2013481.","journal-title":"Annual Review of Physiology"},{"key":"9278_CR2","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1242\/dev.112.4.1041","volume":"112","author":"S Ausoni","year":"1991","unstructured":"Ausoni, S., et al. (1991). Developmental expression of rat cardiac troponin I mRNA. Development, 112, 1041\u20131051.","journal-title":"Development"},{"key":"9278_CR3","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1006\/dbio.1995.1163","volume":"169","author":"L Zhu","year":"1995","unstructured":"Zhu, L., et al. (1995). Developmental regulation of troponin I isoform genes in striated muscles of transgenic mice. Development Biology, 169, 487\u2013503.","journal-title":"Development Biology"},{"key":"9278_CR4","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1161\/01.res.0000435855.49359.47","volume":"80","author":"WD Gao","year":"1997","unstructured":"Gao, W. D., et al. (1997). Role of troponin I proteolysis in the pathogenesis of stunned myocardium. Circulation Research, 80, 393\u2013399.","journal-title":"Circulation Research"},{"key":"9278_CR5","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1161\/01.RES.69.5.1409","volume":"69","author":"NM Hunkeler","year":"1991","unstructured":"Hunkeler, N. M., Kullman, J., & Murphy, A. M. (1991). Troponin I isoform expression in human heart. Circulation Research, 69, 1409\u20131414.","journal-title":"Circulation Research"},{"key":"9278_CR6","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1152\/ajpheart.01379.2006","volume":"293","author":"J Liu","year":"2007","unstructured":"Liu, J., et al. (2007). Progressive troponin I loss impairs cardiac relaxation and causes heart failure in mice. American Journal of Physiology Heart and Circulatory Physiology, 293, 1273\u20131281.","journal-title":"American Journal of Physiology Heart and Circulatory Physiology"},{"key":"9278_CR7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1161\/01.RES.84.1.1","volume":"84","author":"X Huang","year":"1999","unstructured":"Huang, X., et al. (1999). Cardiac troponin I gene knockout: a mouse model of myocardial troponin I deficiency. Circulation Research, 84, 1\u20138.","journal-title":"Circulation Research"},{"key":"9278_CR8","doi-asserted-by":"crossref","first-page":"2221","DOI":"10.1006\/jmcc.2000.1249","volume":"32","author":"X Huang","year":"2000","unstructured":"Huang, X., et al. (2000). Thyroid hormone regulates slow skeletal troponin I gene inactivation in cardiac troponin I null mouse hearts. Journal of Molecular and Cellular Cardiology, 32, 2221\u20132228.","journal-title":"Journal of Molecular and Cellular Cardiology"},{"key":"9278_CR9","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/s11373-008-9246-y","volume":"15","author":"J Du","year":"2008","unstructured":"Du, J., et al. (2008). Functional characterization of mouse fetal TnI gene promoters in myocardial cells. Journal of Biomedical Science, 15, 605\u2013613.","journal-title":"Journal of Biomedical Science"},{"key":"9278_CR10","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.bbrc.2008.10.174","volume":"378","author":"C Nan","year":"2009","unstructured":"Nan, C., & Huang, X. (2009). Transcription factor Yin Yang 1 represses fetal troponin I gene expression in neonatal myocardial cells. Biochemical and biophysical research communications, 378, 62\u201367.","journal-title":"Biochemical and biophysical research communications"},{"key":"9278_CR11","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.1128\/MCB.16.5.2408","volume":"16","author":"M Nakayama","year":"1996","unstructured":"Nakayama, M., Cheng, J., Stauffer, J., Banerjee-Basu, S., Wawrousek, E., & Buonanno, A. (1996). Common core sequences are found in skeletal muscle slow-, fast-fiber-type-specific regulatory elements. Molecular and Cellular Biology, 16, 2408\u20132417.","journal-title":"Molecular and Cellular Biology"},{"key":"9278_CR12","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1128\/MCB.19.1.515","volume":"19","author":"S Calvo","year":"1999","unstructured":"Calvo, S., et al. (1999). Fiber-type-specific transcription of the troponin I slow gene is regulated by multiple elements. Molecular and Cellular Biology, 19, 515\u2013525.","journal-title":"Molecular and Cellular Biology"},{"key":"9278_CR13","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.lfs.2010.10.009","volume":"87","author":"H Sun","year":"2010","unstructured":"Sun, H., et al. (2010). Inhibition of p300-HAT results in a reduced histone acetylation and down-regulation of gene expression in cardiac myocytes. Life Sciences, 87, 707\u2013714.","journal-title":"Life Sciences"},{"key":"9278_CR14","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0955-0674(00)00208-8","volume":"13","author":"JC Rice","year":"2001","unstructured":"Rice, J. C., & Allis, C. D. (2001). Histone methylation versus histone acetylation: new insights into epigenetic regulation. Current Opinion in Cell Biology, 13, 263\u2013273.","journal-title":"Current Opinion in Cell Biology"},{"key":"9278_CR15","first-page":"381","volume":"19","author":"CR Vakoc","year":"2005","unstructured":"Vakoc, C. R., Mandat, S. A., Olenchock, B. A., & Blobel, G. A. (2005). Histone H3 lysine 9 methylation and HP1 gamma are associated with transcription elongation through mammalian chromatin. Molecular and Cellular Biology, 19, 381\u2013391.","journal-title":"Molecular and Cellular Biology"},{"key":"9278_CR16","doi-asserted-by":"crossref","first-page":"7357","DOI":"10.1073\/pnas.0401866101","volume":"101","author":"G Liang","year":"2004","unstructured":"Liang, G., et al. (2004). Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome. Proceedings of the National Academy of Sciences of the United States of America, 101, 7357\u20137362.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"9278_CR17","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1515\/CCLM.1999.002","volume":"37","author":"JP Chapelle","year":"2005","unstructured":"Chapelle, J. P. (2005). Cardiac Troponin I and Troponin T: Recent Players in the Field of Myocardial Markers. Clinical Chemistry and Laboratory Medicine, 37, 11\u201320.","journal-title":"Clinical Chemistry and Laboratory Medicine"},{"key":"9278_CR18","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/j.clinbiochem.2013.04.013","volume":"46","author":"AH Wu","year":"2013","unstructured":"Wu, A. H., & Christenson, R. H. (2013). Analytical and assay issues for use of cardiac troponin testing for risk stratification in primary care. Clinical Biochemistry, 46, 969\u2013978.","journal-title":"Clinical Biochemistry"},{"key":"9278_CR19","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1161\/01.RES.72.5.932","volume":"72","author":"S Sasse","year":"1993","unstructured":"Sasse, S., Brand, N. J., Kyprianou, P., Dhoot, G. K., Wade, R., Arai, M., et al. (1993). Troponin I gene expression during human cardiac development and in end-stage heart failure. Circulation Research, 72, 932\u2013938.","journal-title":"Circulation Research"},{"key":"9278_CR20","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/1050-1738(92)90046-U","volume":"2","author":"KR Boheler","year":"1992","unstructured":"Boheler, K. R., & Schwartz, K. (1992). Gene expression in cardiac hypertrophy. Trends in Cardiovascular Medicine, 2, 176\u2013182.","journal-title":"Trends in Cardiovascular Medicine"},{"key":"9278_CR21","first-page":"65","volume":"6","author":"DV Cumming","year":"1995","unstructured":"Cumming, D. V., et al. (1995). Troponin I and T protein expression in experimental cardiac hypertrophy. Cardioscience, 6, 65\u201370.","journal-title":"Cardioscience"},{"key":"9278_CR22","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1006\/dbio.1995.1163","volume":"169","author":"L Zhu","year":"1995","unstructured":"Zhu, L., Lyons, G. E., Juhasz, O., Joya, J. E., Hardman, E. C., & Wade, R. (1995). Developmental regulation of troponin I isoform genes in striated muscles of transgenic mice. Developmental Biology, 169, 487\u2013503.","journal-title":"Developmental Biology"},{"key":"9278_CR23","doi-asserted-by":"crossref","first-page":"7019","DOI":"10.1128\/MCB.13.11.7019","volume":"13","author":"S Banerjee-Basu","year":"1993","unstructured":"Banerjee-Basu, S., & Buonanno, A. (1993). cis-acting sequences of the rat troponin I slow gene confer tissue- and development-specific transcription in cultured muscle cells as well as fiber type specificity in transgenic mice. Molecular and Cellular Biology, 13, 7019\u20137028.","journal-title":"Molecular and Cellular Biology"},{"key":"9278_CR24","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1007\/s003350010171","volume":"11","author":"Paul JR Barton","year":"2000","unstructured":"Barton, Paul J. R., Mullen, Antony J., Cullen, Martin E., et al. (2000). Genes encoding troponin I and troponin T are organized as three paralogous pairs in the mouse genome. Mammalian Genome, 11, 926\u2013929.","journal-title":"Mammalian Genome"},{"key":"9278_CR25","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1023\/B:MCBI.0000041850.37415.b8","volume":"263","author":"Martin E Cullen","year":"2004","unstructured":"Cullen, Martin E., Dellow, Kimberley A., & Barton, Paul J. R. (2004). Structure and regulation of human troponin genes. Molecular and Cellular Biochemistry, 263, 81\u201390.","journal-title":"Molecular and Cellular Biochemistry"}],"container-title":["Cardiovascular Toxicology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12012-014-9278-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12012-014-9278-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12012-014-9278-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,19]],"date-time":"2022-04-19T13:36:39Z","timestamp":1650375399000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12012-014-9278-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,9]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["9278"],"URL":"https:\/\/doi.org\/10.1007\/s12012-014-9278-7","relation":{},"ISSN":["1530-7905","1559-0259"],"issn-type":[{"value":"1530-7905","type":"print"},{"value":"1559-0259","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,9]]}}}