{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T13:02:51Z","timestamp":1782133371180,"version":"3.54.5"},"reference-count":114,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,11,17]],"date-time":"2018-11-17T00:00:00Z","timestamp":1542412800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cardiovasc Toxicol"],"published-print":{"date-parts":[[2019,2]]},"DOI":"10.1007\/s12012-018-9491-x","type":"journal-article","created":{"date-parts":[[2018,11,17]],"date-time":"2018-11-17T05:02:05Z","timestamp":1542430925000},"page":"1-12","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Nano-medicine and Vascular Endothelial Dysfunction: Options and Delivery Strategies"],"prefix":"10.1007","volume":"19","author":[{"given":"Gaurav","family":"Taneja","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akash","family":"Sud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narayan","family":"Pendse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bishnu","family":"Panigrahi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashish","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arun K.","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,11,17]]},"reference":[{"key":"9491_CR1","doi-asserted-by":"publisher","first-page":"2216","DOI":"10.1016\/j.bbadis.2013.08.006","volume":"1832","author":"CM Sena","year":"2013","unstructured":"Sena, C. M., Pereira, A. M., & Sei\u00e7a, R. (2013). Endothelial dysfunction\u2014A major mediator of diabetic vascular disease. Biochimica et Biophysica Acta, 1832, 2216\u20132231.","journal-title":"Biochimica et Biophysica Acta"},{"key":"9491_CR2","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.7150\/ijbs.7502","volume":"9","author":"P Rajendran","year":"2013","unstructured":"Rajendran, P., Rengarajan, T., Thangavel, J., Nishigaki, Y., Sakthisekaran, D., Sethi, G., et al. (2013). The vascular endothelium and human disease. International Journal of Biological Sciences, 9, 1057\u20131069.","journal-title":"International Journal of Biological Sciences"},{"key":"9491_CR3","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1111\/j.1540-8191.2001.tb01148.x","volume":"17","author":"LJ Ignarro","year":"2002","unstructured":"Ignarro, L. J. (2002). Visiting professorial lecture: Nitric oxide in the regulation of vascular function: an historical overview. Journal of Cardiac Surgery, 17, 301\u2013306.","journal-title":"Journal of Cardiac Surgery"},{"key":"9491_CR4","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1093\/cvr\/cvs100","volume":"94","author":"S Momi","year":"2012","unstructured":"Momi, S., Monopoli, A., Alberti, P. F., Falcinelli, E., Corazzi, T., Conti, V., et al. (2012). Nitric oxide enhances the anti-inflammatory and anti-atherogenic activity of atorvastatin in a mouse model of accelerated atherosclerosis. Cardiovascular Research, 94, 428\u2013438.","journal-title":"Cardiovascular Research"},{"key":"9491_CR5","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1093\/eurheartj\/ehr304","volume":"33","author":"U F\u00f6rstermann","year":"2012","unstructured":"F\u00f6rstermann, U., & Sessa, W. C. (2012). Nitric oxide synthases: Regulation and function. European Heart Journal, 33, 829\u2013837.","journal-title":"European Heart Journal"},{"key":"9491_CR6","doi-asserted-by":"publisher","first-page":"719","DOI":"10.4330\/wjc.v7.i11.719","volume":"7","author":"JB Su","year":"2015","unstructured":"Su, J. B. (2015). Vascular endothelial dysfunction and pharmacological treatment. World Journal of Cardiology, 7, 719\u2013741.","journal-title":"World Journal of Cardiology"},{"key":"9491_CR7","doi-asserted-by":"publisher","first-page":"3045","DOI":"10.1113\/JP271836","volume":"594","author":"M El Assar","year":"2016","unstructured":"El Assar, M., Angulo, J., Santos-Ruiz, M., Ruiz de Adana, J. C., Pindado, M. L., S\u00e1nchez-Ferrer, A., et al. (2016). Asymmetric dimethylarginine (ADMA) elevation and arginase up-regulation contribute to endothelial dysfunction related to insulin resistance in rats and morbidly obese humans. The Journal of Physiology, 594, 3045\u20133060.","journal-title":"The Journal of Physiology"},{"key":"9491_CR8","doi-asserted-by":"publisher","first-page":"11147","DOI":"10.1021\/acs.chemrev.5b00116","volume":"115","author":"Y Min","year":"2015","unstructured":"Min, Y., Caster, J. M., Eblan, M. J., & Wang, A. Z. (2015). Clinical translation of nanomedicine. Chemical Reviews, 115, 11147\u201311190.","journal-title":"Chemical Reviews"},{"key":"9491_CR9","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/2008-2231-20-26","volume":"20","author":"A Pourmand","year":"2012","unstructured":"Pourmand, A., Pourmand, M. R., Wang, J., & Shesser, R. (2012). Application of nanomedicine in emergency medicine; Point-of-care testing and drug delivery in twenty-first century. Daru, 20, 26.","journal-title":"Daru"},{"key":"9491_CR10","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1053\/j.ackd.2013.07.006","volume":"20","author":"C Brede","year":"2013","unstructured":"Brede, C., & Labhasetwar, V. (2013). Applications of nanoparticles in the detection and treatment of kidney diseases. Advances in Chronic Kidney Disease, 20, 454\u2013465.","journal-title":"Advances in Chronic Kidney Disease"},{"key":"9491_CR11","doi-asserted-by":"publisher","first-page":"10530","DOI":"10.1021\/acs.chemrev.5b00321","volume":"115","author":"AB Chinen","year":"2015","unstructured":"Chinen, A. B., Guan, C. M., Ferrer, J. R., Barnaby, S. N., Merkel, T. J., & Mirkin, C. A. (2015). Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence. Chemical Reviews, 115, 10530\u201310574.","journal-title":"Chemical Reviews"},{"key":"9491_CR12","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.nantod.2014.04.008","volume":"9","author":"S Barua","year":"2014","unstructured":"Barua, S., & Mitragotri, S. (2014). Challenges associated with penetration of nanoparticles across cell and tissue barriers: A review of current status and future prospects. Nano Today, 9, 223\u2013243.","journal-title":"Nano Today"},{"key":"9491_CR13","doi-asserted-by":"publisher","first-page":"675","DOI":"10.3762\/bjnano.7.60","volume":"7","author":"Y Zhang","year":"2016","unstructured":"Zhang, Y., & Yang, W. X. (2016). Tight junction between endothelial cells: The interaction between nanoparticles and blood vessels. Beilstein Journal of Nanotechnology, 7, 675\u2013684.","journal-title":"Beilstein Journal of Nanotechnology"},{"key":"9491_CR14","doi-asserted-by":"publisher","DOI":"10.2174\/1871529X18666180508113253","author":"P Gupta","year":"2018","unstructured":"Gupta, P., Garcia, E., Sarkar, A., Kapoor, S., Rafiq, K., Chand, H. S., et al. (2018). Nanoparticle based treatment for cardiovascular diseases. Cardiovascular & Hematological Disorders Drug Targets. \n                    https:\/\/doi.org\/10.2174\/1871529X18666180508113253\n                    \n                  .","journal-title":"Cardiovascular & Hematological Disorders Drug Targets"},{"key":"9491_CR15","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.jsps.2017.10.012","volume":"26","author":"SAA Rizvi","year":"2018","unstructured":"Rizvi, S. A. A., & Saleh, A. M. (2018). Applications of nanoparticle systems in drug delivery technology. Saudi Pharmaceutical Journal, 26, 64\u201370.","journal-title":"Saudi Pharmaceutical Journal"},{"key":"9491_CR16","doi-asserted-by":"publisher","first-page":"9090325","DOI":"10.1155\/2017\/9090325","volume":"2017","author":"ST Jahan","year":"2017","unstructured":"Jahan, S. T., Sadat, S. M. A., Walliser, M., & Haddadi, A. (2017). Targeted therapeutic nanoparticles: An immense promise to fight against cancer. Journal of drug delivery, 2017, 9090325.","journal-title":"Journal of drug delivery"},{"key":"9491_CR17","doi-asserted-by":"publisher","first-page":"36870","DOI":"10.1039\/C6RA03890E","volume":"6","author":"AK Sharma","year":"2016","unstructured":"Sharma, A. K., Kumar, A., Taneja, G., Nagaich, U., Deep, A., & Rajput, S. K. (2016). Synthesis and preliminary therapeutic evaluation of copper nanoparticles against diabetes mellitus and -induced micro (renal) and macro vascular (vascular endothelial and cardiovascular) abnormalities in rats. RSC Advances, 6, 36870\u201336880.","journal-title":"RSC Advances"},{"key":"9491_CR18","doi-asserted-by":"publisher","first-page":"35938","DOI":"10.1039\/C7RA04866A","volume":"7","author":"AK Sharma","year":"2017","unstructured":"Sharma, A. K., Kumar, A., Kumar, S., Mukherjee, S., Nagpal, D., Nagaich, U., et al. (2017). Preparation and therapeutic evolution of Ficus benjamina solid lipid nanoparticles against alcohol abuse\/antabuse induced hepatotoxicity and cardio-renal injury. RSC Advances, 7, 35938\u201335949.","journal-title":"RSC Advances"},{"key":"9491_CR19","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1016\/j.pharep.2018.02.023","volume":"70","author":"AK Sharma","year":"2018","unstructured":"Sharma, A. K., Kumar, A., Taneja, G., Nagaich, U., Deep, A., Datusalia, A. K., et al. (2018). Combined and individual strategy of exercise generated preconditioning and low dose copper nanoparticles serve as superlative approach to ameliorate ISO-induced myocardial infarction in rats. Pharmacological Reports, 70, 789\u2013795.","journal-title":"Pharmacological Reports"},{"key":"9491_CR20","doi-asserted-by":"publisher","first-page":"801896","DOI":"10.1155\/2014\/801896","volume":"2014","author":"G Favero","year":"2014","unstructured":"Favero, G., Paganelli, C., Buffoli, B., Rodella, L. F., & Rezzani, R. (2014). Endothelium and its alterations in cardiovascular diseases: Life style intervention. Biomed Research International, 2014, 801896.","journal-title":"Biomed Research International"},{"key":"9491_CR21","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1007\/s11010-006-2679-6","volume":"283","author":"DI Shah","year":"2006","unstructured":"Shah, D. I., & Singh, M. (2006). Involvement of Rho-kinase in experimental vascular endothelial dysfunction. Molecular and Cellular Biochemistry, 283, 191\u2013199.","journal-title":"Molecular and Cellular Biochemistry"},{"key":"9491_CR22","doi-asserted-by":"publisher","first-page":"215","DOI":"10.3109\/03009734.2014.908253","volume":"119","author":"B Yilmaz","year":"2014","unstructured":"Yilmaz, B., Yilmaz, P., Ordueri, E., Celik-Ozenci, C., & Tasatargil, A. (2014). Poly(ADP-ribose) polymerase inhibition improves endothelin-1-induced endothelial dysfunction in rat thoracic aorta. Upsala Journal of Medical Sciences, 119, 215\u2013222.","journal-title":"Upsala Journal of Medical Sciences"},{"key":"9491_CR23","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.yjmcc.2016.09.002","volume":"101","author":"PA Thiebaut","year":"2016","unstructured":"Thiebaut, P. A., Besnier, M., Gomez, E., & Richard, V. (2016). Role of protein tyrosine phosphatase 1B in cardiovascular diseases. Journal of Molecular and Cellular Cardiology, 101, 50\u201357.","journal-title":"Journal of Molecular and Cellular Cardiology"},{"key":"9491_CR24","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.tox.2007.12.011","volume":"245","author":"P Balakumar","year":"2008","unstructured":"Balakumar, P., Kaur, T., & Singh, M. (2008). Potential target sites to modulate vascular endothelial dysfunction: Current perspectives and future directions. Toxicology, 245, 49\u201364.","journal-title":"Toxicology"},{"key":"9491_CR25","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1007\/s12012-012-9190-y","volume":"13","author":"G Taneja","year":"2013","unstructured":"Taneja, G., Mahadevan, N., & Balakumar, P. (2013). Fish oil blunted nicotine-induced vascular endothelial abnormalities possibly via activation of PPAR\u03b3-eNOS-NO signals. Cardiovascular Toxicology, 13, 110\u2013122.","journal-title":"Cardiovascular Toxicology"},{"key":"9491_CR26","doi-asserted-by":"publisher","first-page":"1591","DOI":"10.1111\/bph.13517","volume":"174","author":"A Daiber","year":"2017","unstructured":"Daiber, A., Steven, S., Weber, A., Shuvaev, V. V., Muzykantov, V. R., Laher, I., et al. (2017). Targeting vascular (endothelial) dysfunction. British Journal of Pharmacology, 174, 1591\u20131619.","journal-title":"British Journal of Pharmacology"},{"key":"9491_CR27","doi-asserted-by":"publisher","first-page":"786","DOI":"10.7150\/ijms.4563","volume":"9","author":"A Guven","year":"2012","unstructured":"Guven, A., & Tolun, F. (2012). Effects of smokeless tobacco \u201cMaras Powder\u201d use on nitric oxide and cardiovascular risk parameters. International Journal of Medical Sciences, 9, 786\u2013792.","journal-title":"International Journal of Medical Sciences"},{"key":"9491_CR28","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/j.taap.2005.03.001","volume":"208","author":"TC Tsou","year":"2005","unstructured":"Tsou, T. C., Tsai, F. Y., Hsieh, Y. W., Li, L. A., Yeh, S. C., & Chang, L. W. (2005). Arsenite induces endothelial cytotoxicity by down-regulation of vascular endothelial nitric oxide synthase. Toxicology and Applied Pharmacology, 208, 277\u2013284.","journal-title":"Toxicology and Applied Pharmacology"},{"key":"9491_CR29","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1136\/bmj.j909","volume":"356","author":"S Bell","year":"2017","unstructured":"Bell, S., Daskalopoulou, M., Rapsomanki, E., George, J., Britton, A., Bobak, M., et al. (2017). Association between clinically recorded alcohol consumption and initial presentation of 12 cardiovascular diseases: Population-based cohort study using linked health records. BMJ, 356, 909.","journal-title":"BMJ"},{"key":"9491_CR30","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.tcm.2006.11.005","volume":"17","author":"CA Papaharalambus","year":"2007","unstructured":"Papaharalambus, C. A., & Griendling, K. K. (2007). Basic mechanisms of oxidative stress and reactive oxygen species in cardiovascular injury. Trends in Cardiovascular Medicine, 17, 48\u201354.","journal-title":"Trends in Cardiovascular Medicine"},{"key":"9491_CR31","doi-asserted-by":"publisher","first-page":"81","DOI":"10.14336\/AD.2015.0803","volume":"7","author":"X Castellon","year":"2016","unstructured":"Castellon, X., & Bogdanova, V. (2016). Chronic inflammatory diseases and endothelial dysfunction. Aging and Disease, 7, 81\u201389.","journal-title":"Aging and Disease"},{"key":"9491_CR32","doi-asserted-by":"publisher","first-page":"1510","DOI":"10.1038\/s41598-018-20027-7","volume":"8","author":"RY Kiseleva","year":"2018","unstructured":"Kiseleva, R. Y., Greineder, C. F., Villa, C. H., Marcos-Contreras, O. A., Hood, E. D., Shuvaev, V. V., et al. (2018). Vascular endothelial effects of collaborative binding to platelet\/endothelial cell adhesion molecule-1 (PECAM-1). Science Reports, 8, 1510.","journal-title":"Science Reports"},{"key":"9491_CR33","doi-asserted-by":"publisher","first-page":"1460","DOI":"10.1097\/HJH.0000000000001750","volume":"36","author":"T Maruhashi","year":"2018","unstructured":"Maruhashi, T., Kihara, Y., & Higashi, Y. (2018). Assessment of endothelium-independent vasodilation: From methodology to clinical perspectives. Journal of Hypertension, 36, 1460\u20131467.","journal-title":"Journal of Hypertension"},{"key":"9491_CR34","doi-asserted-by":"publisher","first-page":"1358","DOI":"10.1161\/CIRCRESAHA.111.243246","volume":"108","author":"S Zimmer","year":"2011","unstructured":"Zimmer, S., Steinmetz, M., Asdonk, T., Motz, I., Coch, C., Hartmann, E., et al. (2011). Activation of endothelial toll-like receptor 3 impairs endothelial function. Circulation Research, 108, 1358\u20131366.","journal-title":"Circulation Research"},{"key":"9491_CR35","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1146\/annurev-pathol-020712-163936","volume":"9","author":"JL Witztum","year":"2014","unstructured":"Witztum, J. L., & Lichtman, A. H. (2014). The influence of innate and adaptive immune responses on atherosclerosis. Annual Review of Pathology, 9, 73\u2013102.","journal-title":"Annual Review of Pathology"},{"key":"9491_CR36","doi-asserted-by":"publisher","first-page":"57267","DOI":"10.1039\/C5RA07927F","volume":"5","author":"AK Sharma","year":"2015","unstructured":"Sharma, A. K., Taneja, G., Khanna, D., & Rajput, S. K. (2015). Reactive oxygen species: Friend or foe? RSC Advances, 5, 57267\u201357276.","journal-title":"RSC Advances"},{"key":"9491_CR37","doi-asserted-by":"publisher","first-page":"103","DOI":"10.3389\/fphys.2012.00103","volume":"3","author":"OC Baltatu","year":"2012","unstructured":"Baltatu, O. C., Iliescu, R., Zaugg, C. E., Reckelhoff, J. F., Louie, P., Schumacher, C., et al. (2012). Antidiuretic effects of the endothelin receptor antagonist avosentan. Frontiers in Physiology, 3, 103.","journal-title":"Frontiers in Physiology"},{"key":"9491_CR38","doi-asserted-by":"publisher","first-page":"373","DOI":"10.2165\/0129784-200808060-00004","volume":"8","author":"BA Golomb","year":"2008","unstructured":"Golomb, B. A., & Evans, M. A. (2008). Statin adverse effects: A review of the literature and evidence for a mitochondrial mechanism. American Journal of Cardiovascular Drugs, 8, 373\u2013418.","journal-title":"American Journal of Cardiovascular Drugs"},{"key":"9491_CR39","first-page":"73","volume":"2","author":"H Shahbazian","year":"2013","unstructured":"Shahbazian, H., & Rezaii, I. (2013). Diabetic kidney disease; Review of the current knowledge. Journal of Renal Injury Prevention, 2, 73\u201380.","journal-title":"Journal of Renal Injury Prevention"},{"key":"9491_CR40","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1111\/j.1751-7176.2011.00508.x","volume":"13","author":"JL Izzo Jr.","year":"2011","unstructured":"Izzo, J. L. Jr., & Weir, M. R. (2011). Angiotensin-converting enzyme inhibitors. The Journal of Clinical Hypertension (Greenwich), 13, 667\u2013675.","journal-title":"The Journal of Clinical Hypertension (Greenwich)"},{"key":"9491_CR41","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1016\/j.jsps.2016.04.010","volume":"24","author":"R Gong","year":"2016","unstructured":"Gong, R., & Chen, G. (2016). Preparation and application of functionalized nano drug carriers. Saudi Pharmaceutical Journal, 24, 254\u2013257.","journal-title":"Saudi Pharmaceutical Journal"},{"key":"9491_CR42","doi-asserted-by":"publisher","first-page":"2971","DOI":"10.1039\/c2cs15344k","volume":"41","author":"N Kamaly","year":"2012","unstructured":"Kamaly, N., Xiao, Z., Valencia, P. M., Radovic-Moreno, A. F., & Farokhzad, O. C. (2012). Targeted polymeric therapeutic nanoparticles: Design, development and clinical translation. Chemical Society Reviews, 41, 2971\u20133010.","journal-title":"Chemical Society Reviews"},{"key":"9491_CR43","doi-asserted-by":"publisher","first-page":"87","DOI":"10.3389\/fcvm.2017.00087","volume":"4","author":"S Katsuki","year":"2017","unstructured":"Katsuki, S., Matoba, T., Koga, J. I., Nakano, K., & Egashira, K. (2017). Anti-inflammatory nano-medicine for cardiovascular disease. Frontiers in Cardiovascular Medicine, 4, 87.","journal-title":"Frontiers in Cardiovascular Medicine"},{"key":"9491_CR44","doi-asserted-by":"publisher","first-page":"2313","DOI":"10.1021\/acsnano.6b06040","volume":"11","author":"B Pelaz","year":"2017","unstructured":"Pelaz, B., Alexiou, C., Alvarez-Puebla, R. A., Alves, F., Andrews, A. M., Ashraf, S., et al. (2017). Diverse applications of nanomedicine. ACS Nano, 11, 2313\u20132381","journal-title":"ACS Nano"},{"key":"9491_CR45","doi-asserted-by":"publisher","first-page":"171","DOI":"10.2217\/nnm.15.189","volume":"11","author":"J Catalan-Figueroa","year":"2016","unstructured":"Catalan-Figueroa, J., Palma-Florez, S., Alvarez, G., Fritz, H. F., Jara, M. O., & Morales, J. O. (2016). Nanomedicine and nanotoxicology: The pros and cons for neurodegeneration and brain cancer. Nanomedicine (London), 11, 171\u2013187.","journal-title":"Nanomedicine (London)"},{"key":"9491_CR46","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1016\/j.jconrel.2015.09.055","volume":"219","author":"VV Shuvaev","year":"2015","unstructured":"Shuvaev, V. V., Brenner, J. S., & Muzykantov, V. R. (2015). Targeted endothelial nanomedicine for common acute pathological conditions. Journal of Controlled Release, 219, 576\u2013595.","journal-title":"Journal of Controlled Release"},{"key":"9491_CR47","doi-asserted-by":"publisher","first-page":"1818","DOI":"10.1289\/ehp.8871","volume":"114","author":"MR Gwinn","year":"2006","unstructured":"Gwinn, M. R., & Vallyathan, V. (2006). Nanoparticles: Health effects\u2014pros and cons. Environmental Health Perspectives, 114, 1818\u20131825.","journal-title":"Environmental Health Perspectives"},{"key":"9491_CR48","doi-asserted-by":"publisher","first-page":"7581","DOI":"10.1021\/cr400372p","volume":"114","author":"K Peynshaert","year":"2014","unstructured":"Peynshaert, K., Manshian, B. B., Joris, F., Braeckmans, K., De Smedt, S. C., Demeester, J., et al. (2014). Exploiting intrinsic nanoparticle toxicity: The pros and cons of nanoparticle-induced autophagy in biomedical research. Chemical Reviews, 114, 7581\u20137609.","journal-title":"Chemical Reviews"},{"key":"9491_CR49","doi-asserted-by":"publisher","first-page":"3979","DOI":"10.1038\/s41598-017-03729-2","volume":"7","author":"S Jatana","year":"2017","unstructured":"Jatana, S., Palmer, B. C., Phelan, S. J., & DeLouise, L. A. (2017). Immunomodulatory effects of nanoparticles on skin allergy. Scientific Reports, 7, 3979.","journal-title":"Scientific Reports"},{"key":"9491_CR50","doi-asserted-by":"publisher","first-page":"1629","DOI":"10.1097\/TP.0000000000001100","volume":"100","author":"E Tasciotti","year":"2016","unstructured":"Tasciotti, E., Cabrera, F. J., Evangelopoulos, M., Martinez, J. O., Thekkedath, U. R., Kloc, M., et al. (2016). The emerging role of nanotechnology in cell and organ transplantation. Transplantation, 100, 1629\u20131638.","journal-title":"Transplantation"},{"key":"9491_CR51","doi-asserted-by":"publisher","first-page":"2231","DOI":"10.1016\/j.biomaterials.2009.01.005","volume":"30","author":"C Salvador-Morales","year":"2009","unstructured":"Salvador-Morales, C., Zhang, L., Langer, R., & Farokhzad, O. C. (2009). Immunocompatibility properties of lipid-polymer hybrid nanoparticles with heterogeneous surface functional groups. Biomaterials, 30, 2231\u20132240.","journal-title":"Biomaterials"},{"key":"9491_CR52","doi-asserted-by":"publisher","first-page":"7027","DOI":"10.1002\/anie.201101554","volume":"50","author":"J Shi","year":"2011","unstructured":"Shi, J., Xiao, Z., Votruba, A. R., Vilos, C., & Farokhzad, O. C. (2011). Differentially charged hollow core\/shell lipid-polymer-lipid hybrid nanoparticles for small interfering RNA delivery. Angewandte Chemie International Edition England, 50, 7027\u20137031.","journal-title":"Angewandte Chemie International Edition England"},{"key":"9491_CR53","doi-asserted-by":"publisher","first-page":"6567","DOI":"10.1002\/anie.201001868","volume":"49","author":"W Gao","year":"2010","unstructured":"Gao, W., Langer, R., & Farokhzad, O. C. (2010). Poly (ethylene glycol) with observable shedding. Angewandte Chemie International Edition England, 49, 6567\u20136571.","journal-title":"Angewandte Chemie International Edition England"},{"key":"9491_CR54","doi-asserted-by":"publisher","first-page":"696","DOI":"10.1021\/nn204165v","volume":"6","author":"Z Xiao","year":"2012","unstructured":"Xiao, Z., Levy-Nissenbaum, E., Alexis, F., Lupt\u00e1k, A., Teply, B. A., Chan, J. M., et al. (2012). Engineering of targeted nanoparticles for cancer therapy using internalizing aptamers isolated by cell-uptake selection. ACS Nano, 6, 696\u2013704.","journal-title":"ACS Nano"},{"key":"9491_CR55","doi-asserted-by":"publisher","first-page":"687","DOI":"10.2217\/nnm.12.134","volume":"8","author":"PM Valencia","year":"2013","unstructured":"Valencia, P. M., Pridgen, E. M., Perea, B., Gadde, S., Sweeney, C., Kantoff, P. W., et al. (2013). Synergistic cytotoxicity of irinotecan and cisplatin in dual-drug targeted polymeric nanoparticles. Nanomedicine (London), 8, 687\u2013698.","journal-title":"Nanomedicine (London)"},{"key":"9491_CR56","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1038\/nbt.1989","volume":"29","author":"F Leuschner","year":"2011","unstructured":"Leuschner, F., Dutta, P., Gorbatov, R., Novobrantseva, T. I., Donahoe, J. S., Courties, G., et al. (2011). Therapeutic siRNA silencing in inflammatory monocytes in mice. Nature Biotechnology, 29, 1005\u20131010.","journal-title":"Nature Biotechnology"},{"key":"9491_CR57","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1016\/j.ihj.2017.02.007","volume":"69","author":"P Ambesh","year":"2017","unstructured":"Ambesh, P., Campia, U., Obiagwu, C., Bansal, R., Shetty, V., Hollander, G., et al. (2017). Nanomedicine in coronary artery disease. Indian Heart Journal, 69, 244\u2013251.","journal-title":"Indian Heart Journal"},{"key":"9491_CR58","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1097\/FJC.0b013e3181624aed","volume":"51","author":"P Broz","year":"2008","unstructured":"Broz, P., Ben-Haim, N., Grzelakowski, M., Marsch, S., Meier, W., & Hunziker, P. (2008). Inhibition of macrophage phagocytotic activity by a receptor-targeted polymer vesicle-based drug delivery formulation of pravastatin. Journal of Cardiovascular Pharmacology, 51, 246\u2013252.","journal-title":"Journal of Cardiovascular Pharmacology"},{"key":"9491_CR59","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.atherosclerosis.2018.01.032","volume":"270","author":"CX Maracle","year":"2018","unstructured":"Maracle, C. X., Agca, R., Helder, B., Meeuwsen, J. A. L., Niessen, H. W. M., Biessen, E. A. L., et al. (2018). Noncanonical NF-\u03baB signaling in microvessels of atherosclerotic lesions is associated with inflammation, atheromatous plaque morphology and myocardial infarction. Atherosclerosis, 270, 33\u201341.","journal-title":"Atherosclerosis"},{"key":"9491_CR60","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.tcm.2012.08.009","volume":"23","author":"JW Rhee","year":"2013","unstructured":"Rhee, J. W., & Wu, J. C. (2013). Advances in nanotechnology for the management of coronary artery disease. Trends in Cardiovascular Medicine, 23, 39\u201345.","journal-title":"Trends in Cardiovascular Medicine"},{"key":"9491_CR61","doi-asserted-by":"publisher","first-page":"9815","DOI":"10.1073\/pnas.0903369106","volume":"106","author":"D Peters","year":"2009","unstructured":"Peters, D., Kastantin, M., Kotamraju, V. R., Karmali, P. P., Gujraty, K., Tirrell, M., et al. (2009). Targeting atherosclerosis by using modular, multifunctional micelles. Proceedings of the National Academy of Sciences USA, 106, 9815\u20139819.","journal-title":"Proceedings of the National Academy of Sciences USA"},{"key":"9491_CR62","doi-asserted-by":"publisher","first-page":"2346","DOI":"10.21037\/jtd.2018.01.85","volume":"10","author":"S Franco Di","year":"2018","unstructured":"Di Franco, S., Amarelli, C., Montalto, A., Loforte, A., & Musumeci, F. (2018). Biomaterials and heart recovery: Cardiac repair, regeneration and healing in the MCS era: A state of the \u201cheart.\u201d. Journal of Thoracic Disease, 10, 2346\u20132362.","journal-title":"Journal of Thoracic Disease"},{"key":"9491_CR63","doi-asserted-by":"publisher","first-page":"3424","DOI":"10.1038\/s41598-018-21618-0","volume":"8","author":"JI Kim","year":"2018","unstructured":"Kim, J. I., Kim, J. Y., & Park, C. H. (2018). Fabrication of transparent hemispherical 3D nanofibrous scaffolds with radially aligned patterns via a novel electrospinning method. Scientific Reports, 8, 3424.","journal-title":"Scientific Reports"},{"key":"9491_CR64","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1001\/jama.2017.12856","volume":"319","author":"T Hampton","year":"2018","unstructured":"Hampton, T. (2018). Smart artificial beta cells may help treat diabetes. JAMA, 319, 11\u201312.","journal-title":"JAMA"},{"key":"9491_CR65","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1038\/nchembio.2511","volume":"14","author":"Z Chen","year":"2018","unstructured":"Chen, Z., Wang, J., Sun, W., Archibong, E., Kahkoska, A. R., Zhang, X., et al. (2018). Synthetic beta cells for fusion-mediated dynamic insulin secretion. Nature Chemical Biology, 14, 86\u201393.","journal-title":"Nature Chemical Biology"},{"key":"9491_CR66","doi-asserted-by":"publisher","first-page":"1882","DOI":"10.3109\/10717544.2014.903535","volume":"23","author":"YY Luo","year":"2016","unstructured":"Luo, Y. Y., Xiong, X. Y., Tian, Y., Li, Z. L., Gong, Y. C., & Li, Y. P. (2016). A review of biodegradable polymeric systems for oral insulin delivery. Drug Delivery, 23, 1882\u20131891.","journal-title":"Drug Delivery"},{"key":"9491_CR67","first-page":"548","volume":"7","author":"RM DiSanto","year":"2015","unstructured":"DiSanto, R. M., Subramanian, V., & Gu, Z. (2015). Recent advances in nanotechnology for diabetes treatment. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 7, 548\u2013564.","journal-title":"Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology"},{"key":"9491_CR68","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.diabres.2017.11.018","volume":"136","author":"P Kesharwani","year":"2018","unstructured":"Kesharwani, P., Gorain, B., Low, S. Y., Tan, S. A., Ling, E. C. S., Lim, Y. K., et al. (2018). Nanotechnology based approaches for anti-diabetic drugs delivery. Diabetes Research and Clinical Practice, 136, 52\u201377.","journal-title":"Diabetes Research and Clinical Practice"},{"key":"9491_CR69","doi-asserted-by":"publisher","first-page":"53","DOI":"10.3390\/pharmaceutics9040053","volume":"9","author":"MA Mohammed","year":"2017","unstructured":"Mohammed, M. A., Syeda, J. T. M., Wasan, K. M., & Wasan, E. K. (2017). An overview of chitosan nanoparticles and its application in non-parenteral drug delivery. Pharmaceutics, 9, 53.","journal-title":"Pharmaceutics"},{"key":"9491_CR70","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1021\/bm900035u","volume":"10","author":"F Cui","year":"2009","unstructured":"Cui, F., Qian, F., Zhao, Z., Yin, L., Tang, C., & Yin, C. (2009). Preparation, characterization, and oral delivery of insulin loaded carboxylated chitosan grafted poly(methyl methacrylate) nanoparticles. Biomacromolecules, 10, 1253\u20131258.","journal-title":"Biomacromolecules"},{"key":"9491_CR71","doi-asserted-by":"publisher","first-page":"277","DOI":"10.5455\/2319-2003.ijbcp20140405","volume":"3","author":"MA Woldu","year":"2014","unstructured":"Woldu, M. A., & Lenjisa, J. L. (2014). Nanoparticles and the new era in diabetes management. International Journal of Basic & Clinical Pharmacology, 3, 277\u2013284.","journal-title":"International Journal of Basic & Clinical Pharmacology"},{"key":"9491_CR72","unstructured":"IDF. (2018). Diabetes atlas-8th\u00a0ed. Retrieved Aug 14, 2018, from \n                    http:\/\/www.diabetesatlas.org\/\n                    \n                  ."},{"key":"9491_CR73","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1186\/s12933-017-0621-8","volume":"16","author":"A Solini","year":"2017","unstructured":"Solini, A., Giannini, L., Seghieri, M., Vitolo, E., Taddei, S., Ghiadoni, L., et al. (2017). Dapagliflozin acutely improves endothelial dysfunction, reduces aortic stiffness and renal resistive index in type 2 diabetic patients: A pilot study. Cardiovascular Diabetology, 16, 138.","journal-title":"Cardiovascular Diabetology"},{"key":"9491_CR74","doi-asserted-by":"publisher","first-page":"84","DOI":"10.5528\/wjtm.v3.i2.84","volume":"3","author":"A Samadder","year":"2014","unstructured":"Samadder, A., & Khuda-Bukhsh, A. R. (2014). Nanotechnological approaches in diabetes treatment: A new horizon. World Journal of Translational Medicine, 3, 84\u201395.","journal-title":"World Journal of Translational Medicine"},{"key":"9491_CR75","doi-asserted-by":"publisher","first-page":"2796","DOI":"10.3109\/10717544.2015.1089957","volume":"23","author":"M Cetin","year":"2016","unstructured":"Cetin, M., & Sahin, S. (2016). Microparticulate and nanoparticulate drug delivery systems for metformin hydrochloride. Drug Delivery, 23, 2796\u20132805.","journal-title":"Drug Delivery"},{"key":"9491_CR76","doi-asserted-by":"publisher","first-page":"117","DOI":"10.2147\/IJN.S125153","volume":"13","author":"J Narang","year":"2018","unstructured":"Narang, J., Malhotra, N., Singhal, C., Singh, G., & Pundir, C. S. (2018). Prussian blue nanocubes\/carbon nanospheres heterostructure composite for biosensing of metformin. International Journal of Nanomedicine, 13, 117\u2013120.","journal-title":"International Journal of Nanomedicine"},{"key":"9491_CR77","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/j.biopha.2015.12.015","volume":"77","author":"AK Sharma","year":"2016","unstructured":"Sharma, A. K., Thanikachalam, P. V., & Rajput, S. K. (2016). Albiglutide: Is a better hope against diabetes mellitus? Biomedicine & Pharmacotherapy, 77, 120\u2013128.","journal-title":"Biomedicine & Pharmacotherapy"},{"key":"9491_CR78","doi-asserted-by":"publisher","first-page":"4222","DOI":"10.1021\/acs.molpharmaceut.6b00871","volume":"13","author":"A Beloqui","year":"2016","unstructured":"Beloqui, A., Alhouayek, M., Carradori, D., Vanvarenberg, K., Muccioli, G. G., Cani, P. D., et al. (2016). A mechanistic study on nanoparticle-mediated glucagon-like peptide-1 (GLP-1) secretion from enteroendocrine L cells. Molecular Pharmaceutics, 13, 4222\u20134230.","journal-title":"Molecular Pharmaceutics"},{"key":"9491_CR79","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1016\/j.ejps.2011.10.029","volume":"45","author":"M Jean","year":"2012","unstructured":"Jean, M., Alameh, M., De Jesus, D., Thibault, M., Lavertu, M., Darras, V., et al. (2012). Chitosan-based therapeutic nanoparticles for combination gene therapy and gene silencing of in vitro cell lines relevant to type 2 diabetes. European Journal of Pharmaceutical Sciences, 45, 138\u2013149.","journal-title":"European Journal of Pharmaceutical Sciences"},{"key":"9491_CR80","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1210\/er.2010-0026","volume":"32","author":"ES O\u2019Sullivan","year":"2011","unstructured":"O\u2019Sullivan, E. S., Vegas, A., Anderson, D. G., & Weir, G. C. (2011). Islets transplanted in immunoisolation devices: A review of the progress and the challenges that remain. Endocrine Reviews, 32, 827\u2013844.","journal-title":"Endocrine Reviews"},{"key":"9491_CR81","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1021\/nl203334c","volume":"12","author":"K Ghosh","year":"2012","unstructured":"Ghosh, K., Kanapathipillai, M., Korin, N., McCarthy, J. R., & Ingber, D. E. (2012). Polymeric nanomaterials for islet targeting and immunotherapeutic delivery. Nano Letters, 12, 203\u2013208.","journal-title":"Nano Letters"},{"key":"9491_CR82","doi-asserted-by":"publisher","first-page":"865","DOI":"10.1016\/j.biopha.2016.07.052","volume":"83","author":"TI Shaheen","year":"2016","unstructured":"Shaheen, T. I., El-Naggar, M. E., Hussein, J. S., El-Bana, M., Emara, E., El-Khayat, Z., et al. (2016). Antidiabetic assessment; in vivo study of gold and core-shell silver-gold nanoparticles on streptozotocin-induced diabetic rats. Biomedicine & Pharmacotherapy, 83, 865\u2013875.","journal-title":"Biomedicine & Pharmacotherapy"},{"key":"9491_CR83","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1080\/10611860902718664","volume":"17","author":"Ah Kim","year":"2009","unstructured":"Kim, Ah, Lee, H., Park, S., Lee, J. H., Lee, S., Ihm, B. W., et al. (2009). Enhanced protection of Ins-1 beta cells from apoptosis under hypoxia by delivery of DNA encoding secretion signal peptide-linked exendin-4. Journal of Drug Targeting, 17, 242\u2013248.","journal-title":"Journal of Drug Targeting"},{"key":"9491_CR84","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.cytogfr.2018.01.006","volume":"39","author":"H Goikuria","year":"2018","unstructured":"Goikuria, H., Vandenbroeck, K., & Alloza, I. (2018). Inflammation in human carotid atheroma plaques. Cytokine & Growth Factor Reviews, 39, 62\u201370.","journal-title":"Cytokine & Growth Factor Reviews"},{"key":"9491_CR85","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1007\/s10554-013-0354-z","volume":"30","author":"Y Han","year":"2014","unstructured":"Han, Y., Jing, J., Tu, S., Tian, F., Xue, H., Chen, W., et al. (2014). ST elevation acute myocardial infarction accelerates non-culprit coronary lesion atherosclerosis. The International Journal of Cardiovascular Imaging, 30, 253\u2013261.","journal-title":"The International Journal of Cardiovascular Imaging"},{"key":"9491_CR86","doi-asserted-by":"publisher","first-page":"3065","DOI":"10.1038\/ncomms4065","volume":"5","author":"R Duivenvoorden","year":"2014","unstructured":"Duivenvoorden, R., Tang, J., Cormode, D. P., Mieszawska, A. J., Izquierdo-Garcia, D., Ozcan, C., et al. (2014). A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation. Nature Communications, 5, 3065.","journal-title":"Nature Communications"},{"key":"9491_CR87","doi-asserted-by":"publisher","first-page":"1194","DOI":"10.1258\/ebm.2010.009320","volume":"235","author":"BH Cho","year":"2010","unstructured":"Cho, B. H., Park, J. R., Nakamura, M. T., Odintsov, B. M., Wallig, M. A., & Chung, B. H. (2010). Synthetic dimyristoylphosphatidylcholine liposomes assimilating into high-density lipoprotein promote regression of atherosclerotic lesions in cholesterol-fed rabbits. Experimental Biology and Medicine (Maywood), 235, 1194\u20131203.","journal-title":"Experimental Biology and Medicine (Maywood)"},{"key":"9491_CR88","doi-asserted-by":"publisher","first-page":"2103","DOI":"10.1161\/01.ATV.0000235724.11299.76","volume":"26","author":"PM Winter","year":"2006","unstructured":"Winter, P. M., Neubauer, A. M., Caruthers, S. D., Harris, T. D., Robertson, J. D., Williams, T. A., et al. (2006). Endothelial alpha(v)beta3 integrin-targeted fumagillin nanoparticles inhibit angiogenesis in atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology, 26, 2103\u20132109.","journal-title":"Arteriosclerosis, Thrombosis, and Vascular Biology"},{"key":"9491_CR89","doi-asserted-by":"publisher","DOI":"10.1002\/wnan.1412","author":"J Zhang","year":"2017","unstructured":"Zhang, J., Zu, Y., Dhanasekara, C. S., Li, J., Wu, D., Fan, Z., et al. (2017). Detection and treatment of atherosclerosis using nanoparticles. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. \n                    https:\/\/doi.org\/10.1002\/wnan.1412","journal-title":"Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology"},{"key":"9491_CR90","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1161\/ATVBAHA.115.307057","volume":"36","author":"S Nakashiro","year":"2016","unstructured":"Nakashiro, S., Matoba, T., Umezu, R., Koga, J., Tokutome, M., Katsuki, S., et al. (2016). Pioglitazone-incorporated nanoparticles prevent plaque destabilization and rupture by regulating monocyte\/macrophage differentiation in ApoE-\/- mice. Arteriosclerosis, Thrombosis, and Vascular Biology, 36, 491\u2013500.","journal-title":"Arteriosclerosis, Thrombosis, and Vascular Biology"},{"key":"9491_CR91","doi-asserted-by":"publisher","first-page":"42171","DOI":"10.1038\/srep42171","volume":"7","author":"SB Yong","year":"2017","unstructured":"Yong, S. B., Kim, H. J., Kim, J. K., Chung, J. Y., & Kim, Y. H. (2017). Human CD64-targeted non-viral siRNA delivery system for blood monocyte gene modulation. Scientific Reports, 7, 42171.","journal-title":"Scientific Reports"},{"key":"9491_CR92","doi-asserted-by":"publisher","first-page":"1209","DOI":"10.1016\/j.nano.2014.02.011","volume":"10","author":"M Bartneck","year":"2014","unstructured":"Bartneck, M., Peters, F. M., Warzecha, K. T., Bienert, M., van Bloois, L., Trautwein, C., et al. (2014). Liposomal encapsulation of dexamethasone modulates cytotoxicity, inflammatory cytokine response, and migratory properties of primary human macrophages. Nanomedicine, 10, 1209\u20131220.","journal-title":"Nanomedicine"},{"key":"9491_CR93","doi-asserted-by":"publisher","first-page":"1292","DOI":"10.1111\/j.1538-7836.2011.04339.x","volume":"9","author":"J Myerson","year":"2011","unstructured":"Myerson, J., He, L., Lanza, G., Tollefsen, D., & Wickline, S. (2011). Thrombin-inhibiting perfluorocarbon nanoparticles provide a novel strategy for treatment and magnetic resonance imaging of acute thrombosis. Journal of Thrombosis and Haemostasis, 9, 1292\u20131300.","journal-title":"Journal of Thrombosis and Haemostasis"},{"key":"9491_CR94","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1016\/j.jcin.2011.11.013","volume":"5","author":"LK Pendyala","year":"2012","unstructured":"Pendyala, L. K., Matsumoto, D., Shinke, T., Iwasaki, T., Sugimoto, R., Hou, D., et al. (2012). Nobori stent shows less vascular inflammation and early recovery of endothelial function compared with Cypher stent. JACC Cardiovascular Interventions, 5, 436\u2013444.","journal-title":"JACC Cardiovascular Interventions"},{"key":"9491_CR95","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1161\/01.CIR.0000023532.98469.48","volume":"106","author":"HD Danenberg","year":"2002","unstructured":"Danenberg, H. D., Fishbein, I., Gao, J., M\u00f6nkk\u00f6nen, J., Reich, R., Gati, I., et al. (2002). Macrophage depletion by clodronate-containing liposomes reduces neointimal formation after balloon injury in rats and rabbits. Circulation, 106, 599\u2013605.","journal-title":"Circulation"},{"key":"9491_CR96","doi-asserted-by":"publisher","first-page":"2798","DOI":"10.1161\/01.CIR.0000097002.69209.CD","volume":"108","author":"HD Danenberg","year":"2003","unstructured":"Danenberg, H. D., Golomb, G., Groothuis, A., Gao, J., Epstein, H., Swaminathan, R. V., et al. (2003). Liposomal alendronate inhibits systemic innate immunity and reduces in-stent neointimal hyperplasia in rabbits. Circulation, 108, 2798\u20132804.","journal-title":"Circulation"},{"key":"9491_CR97","doi-asserted-by":"publisher","first-page":"1195","DOI":"10.1161\/01.CIR.0000032141.31476.15","volume":"106","author":"FD Kolodgie","year":"2002","unstructured":"Kolodgie, F. D., John, M., Khurana, C., Farb, A., Wilson, P. S., Acampado, E., et al. (2002). Sustained reduction of in-stent neointimal growth with the use of a novel systemic nanoparticle paclitaxel. Circulation, 106, 1195\u20131198.","journal-title":"Circulation"},{"key":"9491_CR98","doi-asserted-by":"publisher","first-page":"1960","DOI":"10.1161\/ATVBAHA.108.170662","volume":"28","author":"M Joner","year":"2008","unstructured":"Joner, M., Morimoto, K., Kasukawa, H., Steigerwald, K., Merl, S., Nakazawa, G., et al. (2008). Site-specific targeting of nanoparticle prednisolone reduces in-stent restenosis in a rabbit model of established atheroma. Arteriosclerosis, Thrombosis, and Vascular Biology, 28, 1960\u20131966.","journal-title":"Arteriosclerosis, Thrombosis, and Vascular Biology"},{"key":"9491_CR99","doi-asserted-by":"publisher","first-page":"19347","DOI":"10.1073\/pnas.1115945108","volume":"108","author":"JM Chan","year":"2011","unstructured":"Chan, J. M., Rhee, J.-W., Drum, C. L., Bronson, R. T., Golomb, G., Langer, R., et al. (2011). In vivo prevention of arterial restenosis with paclitaxel-encapsulated targeted lipid\u2013polymeric nanoparticles. Proceedings of the National Academy of Sciences USA, 108, 19347\u201319352.","journal-title":"Proceedings of the National Academy of Sciences USA"},{"key":"9491_CR100","doi-asserted-by":"publisher","first-page":"11915","DOI":"10.1073\/pnas.0704581104","volume":"104","author":"CK Hashi","year":"2007","unstructured":"Hashi, C. K., Zhu, Y., Yang, G.-Y., Young, W. L., Hsiao, B. S., Wang, K., et al. (2007). Antithrombogenic property of bone marrow mesenchymal stem cells in nanofibrous vascular grafts. Proceedings of the National Academy of Sciences USA, 104, 11915\u201311920.","journal-title":"Proceedings of the National Academy of Sciences USA"},{"key":"9491_CR101","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.cca.2014.06.029","volume":"437","author":"H Mangge","year":"2014","unstructured":"Mangge, H., Almer, G., Stelzer, I., Reininghaus, E., & Prassl, R. (2014). Laboratory medicine for molecular imaging of atherosclerosis. Clinica Chimica Acta, 437, 19\u201324.","journal-title":"Clinica Chimica Acta"},{"key":"9491_CR102","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1016\/j.nantod.2015.11.009","volume":"10","author":"BL Chung","year":"2015","unstructured":"Chung, B. L., Toth, M. J., Toth, K., Kamaly, N., Sei, Y. J., Becraft, J., et al. (2015). Nanomedicines for endothelial disorders. Nano Today, 10, 759\u2013776.","journal-title":"Nano Today"},{"key":"9491_CR103","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1172\/JCI66843","volume":"123","author":"JK Liao","year":"2013","unstructured":"Liao, J. K. (2013). Linking endothelial dysfunction with endothelial cell activation. Journal of Clinical Investigation, 123, 540\u2013541.","journal-title":"Journal of Clinical Investigation"},{"key":"9491_CR104","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1177\/1535370217693116","volume":"242","author":"K Khodabandehlou","year":"2017","unstructured":"Khodabandehlou, K., Masehi-Lano, J. J., Poon, C., Wang, J., & Chung, E. J. (2017). Targeting cell adhesion molecules with nanoparticles using in vivo and flow-based in vitro models of atherosclerosis. Experimental Biology and Medicine (Maywood), 242, 799\u2013812.","journal-title":"Experimental Biology and Medicine (Maywood)"},{"key":"9491_CR105","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1038\/nrd3578","volume":"10","author":"ME Lobatto","year":"2011","unstructured":"Lobatto, M. E., Fuster, V., Fayad, Z. A., & Mulder, W. J. (2011). Perspectives and opportunities for nanomedicine in the management of atherosclerosis. Nature Reviews Drug Discovery, 10, 835\u2013852.","journal-title":"Nature Reviews Drug Discovery"},{"key":"9491_CR106","doi-asserted-by":"publisher","first-page":"2020","DOI":"10.1021\/mp100309y","volume":"7","author":"ME Lobatto","year":"2010","unstructured":"Lobatto, M. E., Fayad, Z. A., Silvera, S., Vucic, E., Calcagno, C., Mani, V., et al. (2010). Multimodal clinical imaging to longitudinally assess nano-medical anti-inflammatory treatment in experimental atherosclerosis. Molecular Pharmaceutics, 7, 2020\u20132029.","journal-title":"Molecular Pharmaceutics"},{"key":"9491_CR107","doi-asserted-by":"publisher","first-page":"191","DOI":"10.3233\/JCB-15020","volume":"1","author":"I Cicha","year":"2016","unstructured":"Cicha, I. (2016). Strategies to enhance nanoparticle-endothelial interactions under flow. Journal of Cellular Biotehnology, 1, 191\u2013208.","journal-title":"Journal of Cellular Biotehnology"},{"key":"9491_CR108","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1161\/01.RES.0000155722.17881.dd","volume":"96","author":"KA Kelly","year":"2005","unstructured":"Kelly, K. A., Allport, J. R., Tsourkas, A., Shinde-Patil, V. R., Josephson, L., & Weissleder, R. (2005). Detection of vascular adhesion molecule-1 expression using a novel multimodal nanoparticle. Circulation Research, 96, 327\u2013336.","journal-title":"Circulation Research"},{"key":"9491_CR109","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1016\/j.jconrel.2011.09.067","volume":"157","author":"T Bhowmick","year":"2012","unstructured":"Bhowmick, T., Berk, E., Cui, X., Muzykantov, V. R., & Muro, S. (2012). Effect of flow on endothelial endocytosis of nanocarriers targeted to ICAM-1. Journal of Controlled Release, 157, 485\u2013492.","journal-title":"Journal of Controlled Release"},{"key":"9491_CR110","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1148\/radiol.2412050490","volume":"241","author":"PR Reynolds","year":"2006","unstructured":"Reynolds, P. R., Larkman, D. J., Haskard, D. O., Hajnal, J. V., Kennea, N. L., George, A. J., et al. (2006). Detection of vascular expression of E-selectin in vivo with MR imaging. Radiology, 241, 469\u2013476.","journal-title":"Radiology"},{"key":"9491_CR111","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/j.ijpharm.2015.05.032","volume":"490","author":"NS Elbialy","year":"2015","unstructured":"Elbialy, N. S., Fathy, M. M., & Khalil, W. M. (2015). Doxorubicin loaded magnetic gold nanoparticles for in vivo targeted drug delivery. International Journal of Pharmaceutics, 490, 190\u2013199.","journal-title":"International Journal of Pharmaceutics"},{"key":"9491_CR112","doi-asserted-by":"publisher","first-page":"39490","DOI":"10.1371\/journal.pone.0039490","volume":"7","author":"Y Zhang","year":"2012","unstructured":"Zhang, Y., Li, W., Ou, L., Wang, W., Delyagina, E., Lux, C., et al. (2012). Targeted delivery of human VEGF gene via complexes of magnetic nanoparticle-adenoviral vectors enhanced cardiac regeneration. PLoS ONE, 7, 39490.","journal-title":"PLoS ONE"},{"key":"9491_CR113","doi-asserted-by":"publisher","first-page":"3343","DOI":"10.1016\/j.biomaterials.2009.02.034","volume":"30","author":"YH Ma","year":"2009","unstructured":"Ma, Y. H., Wu, S. Y., Wu, T., Chang, Y. J., Hua, M. Y., & Chen, J. P. (2009). Magnetically targeted thrombolysis with recombinant tissue plasminogen activator bound to polyacrylic acid-coated nanoparticles. Biomaterials, 30, 3343\u20133351.","journal-title":"Biomaterials"},{"key":"9491_CR114","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1002\/jbm.a.31346","volume":"84","author":"HL Ma","year":"2008","unstructured":"Ma, H. L., Qi, X. R., Ding, W. X., Ding, W. X., Maitani, Y., & Nagai, T. (2008). Magnetic targeting after femoral artery administration and biocompatibility assessment of superparamagnetic iron oxide nanoparticles. Journal of Biomedical Materials Research Part A, 84, 598\u2013606.","journal-title":"Journal of Biomedical Materials Research Part A"}],"container-title":["Cardiovascular Toxicology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12012-018-9491-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12012-018-9491-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12012-018-9491-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,17]],"date-time":"2019-11-17T00:33:43Z","timestamp":1573950823000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12012-018-9491-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,17]]},"references-count":114,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["9491"],"URL":"https:\/\/doi.org\/10.1007\/s12012-018-9491-x","relation":{},"ISSN":["1530-7905","1559-0259"],"issn-type":[{"value":"1530-7905","type":"print"},{"value":"1559-0259","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,17]]},"assertion":[{"value":"17 November 2018","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"No conflict of interest is declared.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}