{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T17:07:42Z","timestamp":1791824862810,"version":"4.3.4"},"reference-count":72,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2020,3,26]],"date-time":"2020-03-26T00:00:00Z","timestamp":1585180800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,3,26]],"date-time":"2020-03-26T00:00:00Z","timestamp":1585180800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cardiovasc Toxicol"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1007\/s12012-020-09569-3","type":"journal-article","created":{"date-parts":[[2020,3,26]],"date-time":"2020-03-26T16:03:51Z","timestamp":1585238631000},"page":"427-436","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Cardioprotective Effect of Paricalcitol on Amitriptyline-Induced Cardiotoxicity in Rats: Comparison of [99mTc]PYP Cardiac Scintigraphy with Electrocardiographic and Biochemical Findings"],"prefix":"10.1007","volume":"20","author":[{"given":"Hatice","family":"Aygun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nursah","family":"Basol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serdar Savas","family":"Gul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,3,26]]},"reference":[{"issue":"4","key":"9569_CR1","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1136\/emj.18.4.236","volume":"18","author":"GW Kerr","year":"2011","unstructured":"Kerr, G. W., McGuffie, A. C., & Wilkie, S. (2011). Tricyclic antidepressant overdose: A review. Emergency Medicine Journal,18(4), 236\u2013241.","journal-title":"Emergency Medicine Journal"},{"key":"9569_CR2","first-page":"475","volume-title":"Critical care toxicology: diagnosis and management of the critically poisoned patient","author":"K Mills","year":"2005","unstructured":"Mills, K. (2005). Cylic Antidepressants. In J. Brent, K. L. Wallace, & K. K. Burkhart (Eds.), Critical care toxicology: diagnosis and management of the critically poisoned patient (pp. 475\u2013484). Philadelphia: Elsevier Mosby."},{"issue":"5","key":"9569_CR3","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1111\/j.1742-7843.2006.pto_387.x","volume":"98","author":"S Kiyan","year":"2006","unstructured":"Kiyan, S., Aksay, E., Yanturali, S., Atilla, R., & Ersel, M. (2006). Acute myocardial infarction associated with amitriptyline overdose. Basic & Clinical Pharmacology & Toxicology,98(5), 462\u2013466.","journal-title":"Basic & Clinical Pharmacology & Toxicology"},{"issue":"6","key":"9569_CR4","first-page":"554","volume":"22","author":"RM Guthrie","year":"1986","unstructured":"Guthrie, R. M., & Lott, J. A. (1986). Abnormal serum creatine kinase and MB fraction following an amitriptyline overdose. Journal of Family Practice,22(6), 554\u2013555.","journal-title":"Journal of Family Practice"},{"issue":"7","key":"9569_CR5","doi-asserted-by":"publisher","first-page":"945","DOI":"10.1081\/CLT-200041845","volume":"42","author":"S Kalkan","year":"2004","unstructured":"Kalkan, S., Aygoren, O., Akgun, A., et al. (2004). Do adenosine receptors play a role in amitriptyline-induced cardiovascular toxicity in rats? Journal of Toxicology\u2014Clinical Toxicology,42(7), 945\u2013954.","journal-title":"Journal of Toxicology\u2014Clinical Toxicology"},{"issue":"3","key":"9569_CR6","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1056\/NEJMra070553","volume":"357","author":"MF Holick","year":"2007","unstructured":"Holick, M. F. (2007). Vitamin D deficiency. New England Journal of Medicine,357(3), 266\u2013281.","journal-title":"New England Journal of Medicine"},{"issue":"1\u20132","key":"9569_CR7","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1024\/0300-9831\/a000220","volume":"85","author":"A Aleksova","year":"2015","unstructured":"Aleksova, A., Belfiore, R., Carriere, C., et al. (2015). Vitamin D deficiency in patients with acute myocardial infarction: An Italian single-center study. International Journal for Vitamin and Nutrition Research,85(1\u20132), 23\u201330.","journal-title":"International Journal for Vitamin and Nutrition Research"},{"key":"9569_CR8","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1016\/j.amjcard.2010.05.027","volume":"106","author":"JL Anderson","year":"2010","unstructured":"Anderson, J. L., May, H. T., Horne, B. D., et al. (2010). Intermountain heart collaborative (IHC) study group: Relation of vitamin D deficiency to cardiovascular risk factors, disease status, and incident events in a general healthcare population. The American Journal of Cardiology,106, 963\u2013968.","journal-title":"The American Journal of Cardiology"},{"issue":"2","key":"9569_CR9","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1017\/S1047951113002023","volume":"25","author":"O Yilmaz","year":"2015","unstructured":"Yilmaz, O., Olgun, H., Ciftel, M., et al. (2015). Dilated cardiomyopathy secondary to rickets related hypocalcaemia: Eight case reports and a review of the literature. Cardiology in the Young,25(2), 261\u2013266.","journal-title":"Cardiology in the Young"},{"issue":"1","key":"9569_CR10","first-page":"1356","volume":"8","author":"V Polat","year":"2015","unstructured":"Polat, V., Bozcali, E., Uygun, T., et al. (2015). Low vitamin D status associated with dilated cardiomyopathy. International Journal of Clinical and Experimental Medicine,8(1), 1356\u20131362.","journal-title":"International Journal of Clinical and Experimental Medicine"},{"issue":"8","key":"9569_CR11","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1152\/japplphysiol.01506.2012","volume":"114","author":"S Bae","year":"2013","unstructured":"Bae, S., Singh, S. S., Yu, H., et al. (2013). Vitamin D signaling pathway plays an important role in the development of heart failure after myocardial infarction. Journal of Applied Physiology,114(8), 979\u2013987.","journal-title":"Journal of Applied Physiology"},{"issue":"1","key":"9569_CR12","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1159\/000338166","volume":"122","author":"L Gullestad","year":"2012","unstructured":"Gullestad, L., Ueland, T., Vinge, L. E., et al. (2012). Inflammatory cytokines in heart failure: Mediators and markers. Cardiology,122(1), 23\u201335.","journal-title":"Cardiology"},{"key":"9569_CR13","doi-asserted-by":"publisher","first-page":"34","DOI":"10.2174\/1871529X14666140228122836","volume":"14","author":"A Franczyk","year":"2014","unstructured":"Franczyk, A., Stolarz-Skrzypek, K., Weso\u0142owska, A., & Czarnecka, D. (2014). Vitamin D and vitamin D receptor activators in treatment of hypertension and cardiovascular disease. Cardiovascular & Hematological Disorders: Drug Targets,14, 34\u201344.","journal-title":"Cardiovascular & Hematological Disorders: Drug Targets"},{"issue":"4_Suppl","key":"9569_CR14","first-page":"iv17","volume":"27","author":"E Gonzalez-Parra","year":"2012","unstructured":"Gonzalez-Parra, E., Rojas-Rivera, J., Tu\u00f1\u00f3n, J., et al. (2012). Vitamin D receptor activation and cardiovascular disease. Nephrology Dialysis Transplantation,27(4_Suppl), iv17\u2013iv21.","journal-title":"Nephrology Dialysis Transplantation"},{"issue":"2","key":"9569_CR15","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1159\/000266204","volume":"31","author":"R Lund","year":"2010","unstructured":"Lund, R., Andress, D. L., Amdahl, M., et al. (2010). Differential effects of paricalcitol and calcitriol on intestinal calcium absorption in hemodialysis patients. American Journal of Nephrology,31(2), 165\u2013170.","journal-title":"American Journal of Nephrology"},{"key":"9569_CR16","doi-asserted-by":"publisher","DOI":"10.1007\/s00210-019-01683-6","author":"N Basol","year":"2019","unstructured":"Basol, N., Aygun, H., & Gul, S. S. (2019). Beneficial effects of edaravone in experimental model of amitriptyline-induced cardiotoxicity in rats. Naunyn Schmiedebergs Arch Pharmacol.. https:\/\/doi.org\/10.1007\/s00210-019-01683-6.","journal-title":"Naunyn Schmiedebergs Arch Pharmacol."},{"key":"9569_CR17","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1097\/00005344-198011000-00008","volume":"2","author":"G Buschmann","year":"1980","unstructured":"Buschmann, G., Schumacher, W., Budden, R., & K\u00fchl, U. G. (1980). Evaluation of the effect of dopamine and other catecholamines on the electrocardiogram and blood pressure of rats by means of on-line biosignal processing. Journal of Cardiovascular Pharmacology,2, 777\u2013795.","journal-title":"Journal of Cardiovascular Pharmacology"},{"key":"9569_CR18","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1093\/toxsci\/kfr021","volume":"121","author":"AK Farraj","year":"2011","unstructured":"Farraj, A. K., Hazari, M. S., & Cascio, W. E. (2011). The utility of the small rodent electrocardiogram in toxicology. Toxicological Sciences,121, 11\u201330.","journal-title":"Toxicological Sciences"},{"issue":"2","key":"9569_CR19","doi-asserted-by":"publisher","first-page":"119","DOI":"10.4149\/BLL_2019_018","volume":"120","author":"H Aygun","year":"2019","unstructured":"Aygun, H., & Gul, S. S. (2019). Protective effect of melatonin and agomelatine on adriamycin-induced nephrotoxicity in rat model: A renal scintigraphy and biochemical study. Bratislava Medical Journal,120(2), 119\u2013123.","journal-title":"Bratislava Medical Journal"},{"issue":"1","key":"9569_CR20","first-page":"10","volume":"41","author":"H Aygun","year":"2019","unstructured":"Aygun, H., & Gul, S. S. (2019). Protective effect of edaravone on adriamycin-induced cardiotoxicity in rats. Cumhuriyet Medical Journal,41(1), 10\u201318.","journal-title":"Cumhuriyet Medical Journal"},{"issue":"3","key":"9569_CR21","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1177\/0960327112446819","volume":"32","author":"MA Ar\u0131c\u0131","year":"2013","unstructured":"Ar\u0131c\u0131, M. A., Buyukdeligoz, M., Kalkan, S., & Tuncok, Y. (2013). Effects of BQ-788 on amitriptyline-induced cardiovascular toxicity. Human and Experimental Toxicology,32(3), 316\u2013322.","journal-title":"Human and Experimental Toxicology"},{"issue":"1","key":"9569_CR22","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1177\/0960327115574920","volume":"35","author":"N Basol","year":"2016","unstructured":"Basol, N., & Erbas, O. (2016). The effects of diltiazem and metoprolol in QTc prolongation due to amitriptyline intoxication. Human and Experimental Toxicology,35(1), 29\u201334.","journal-title":"Human and Experimental Toxicology"},{"key":"9569_CR23","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1007\/s12012-018-9466-y","volume":"18","author":"S Bora","year":"2018","unstructured":"Bora, S., Erdo\u011fan, M. A., Yi\u011fitt\u00fcrk, G., Erba\u015f, O., & Parlak, I. (2018). The effects of lipid emulsion, magnesium sulphate and metoprolol in amitriptyline-induced cardiovascular toxicity in rats. Cardiovascular Toxicology,18, 547\u2013556.","journal-title":"Cardiovascular Toxicology"},{"issue":"5","key":"9569_CR24","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1177\/1091581813503888","volume":"32","author":"V Sorodoc","year":"2013","unstructured":"Sorodoc, V., Sorodoc, L., Ungureanu, D., Sava, A., & Jaba, I. M. (2013). Cardiac troponin T and NT-proBNP as biomarkers of early myocardial damage in amitriptyline-induced cardiovascular toxicity in rats. International Journal of Toxicology,32(5), 351\u2013357.","journal-title":"International Journal of Toxicology"},{"key":"9569_CR25","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.jsbmb.2016.03.028","volume":"163","author":"M Mizobuchi","year":"2016","unstructured":"Mizobuchi, M., Ogata, H., Yamazaki-Nakazawa, A., et al. (2016). Cardiac effect of vitamin D receptor modulators in uremic rats. Journal of Steroid Biochemistry and Molecular Biology,163, 20\u201327.","journal-title":"Journal of Steroid Biochemistry and Molecular Biology"},{"issue":"4","key":"9569_CR26","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1159\/000355811","volume":"39","author":"C Ritter","year":"2014","unstructured":"Ritter, C., Zhang, S., Finch, J. L., et al. (2014). Cardiac and renal effects of atrasentan in combination with enalapril and paricalcitol in uremic rats. Kidney Blood Pressure Research,39(4), 340\u2013352.","journal-title":"Kidney Blood Pressure Research"},{"issue":"11","key":"9569_CR27","doi-asserted-by":"publisher","first-page":"1831","DOI":"10.1093\/ndt\/gfx060","volume":"32","author":"S Panizo","year":"2017","unstructured":"Panizo, S., Carrillo-L\u00f3pez, N., Naves-D\u00edaz, M., et al. (2017). Regulation of miR-29b and miR-30c by vitamin D receptor activators contributes to attenuate uraemia-induced cardiac fibrosis. Nephrology Dialysis Transplantation,32(11), 1831\u20131840.","journal-title":"Nephrology Dialysis Transplantation"},{"issue":"2","key":"9569_CR28","doi-asserted-by":"publisher","first-page":"622","DOI":"10.2353\/ajpath.2010.091292","volume":"177","author":"J Kong","year":"2010","unstructured":"Kong, J., Kim, G. H., Wei, M., et al. (2010). Therapeutic effects of vitamin D analogs on cardiac hypertrophy in spontaneously hypertensive rats. American Journal of Pathology,177(2), 622\u2013631.","journal-title":"American Journal of Pathology"},{"issue":"11","key":"9569_CR29","first-page":"693","volume":"15","author":"O Havakuk","year":"2013","unstructured":"Havakuk, O., Entin-Meer, M., & Ben-Shoshan, J. (2013). Effect of vitamin D analogues on acute cardiorenal syndrome: A laboratory rat model. Israel Medical Association Journal,15(11), 693\u2013697.","journal-title":"Israel Medical Association Journal"},{"issue":"10","key":"9569_CR30","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.1007\/s00210-016-1273-z","volume":"389","author":"Y Uyan\u0131kgil","year":"2016","unstructured":"Uyan\u0131kgil, Y., Solmaz, V., \u00c7avu\u015fo\u011flu, T., \u00c7\u0131nar, B. P., \u00c7etin, E. \u00d6., Sur, H. Y., et al. (2016). Inhibitor effect of paricalcitol in rat model of pentylenetetrazol-induced seizures. Naunyn-Schmiedeberg's Archives of Pharmacology,389(10), 1117\u20131122.","journal-title":"Naunyn-Schmiedeberg's Archives of Pharmacology"},{"key":"9569_CR31","doi-asserted-by":"publisher","first-page":"106262","DOI":"10.1016\/j.eplepsyres.2019.106262","volume":"159","author":"O Sumbul","year":"2019","unstructured":"Sumbul, O., & Aygun, H. (2019). The effect of vitamin D3 and paricalcitol on penicillin-induced epileptiform activity in rats. Epilepsy Research UK,159, 106262.","journal-title":"Epilepsy Research UK"},{"issue":"3","key":"9569_CR32","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1016\/j.jemermed.2011.09.010","volume":"43","author":"MS Blaber","year":"2012","unstructured":"Blaber, M. S., Khan, J. N., Nrebner, J. A., & McColm, R. (2012). \u201cLipid rescue\u201d for tricyclic antidepressant cardiotoxicity. Journal of Emergency Medicine,43(3), 465\u2013467.","journal-title":"Journal of Emergency Medicine"},{"key":"9569_CR33","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2015-211428","author":"S Clark","year":"2015","unstructured":"Clark, S., Catt, J. W., & Caffery, T. (2015). Rapid diagnosis and treatment of severe tricyclic antidepressant toxicity. BMJ Case Reports. https:\/\/doi.org\/10.1136\/bcr-2015-211428.","journal-title":"BMJ Case Reports"},{"issue":"6","key":"9569_CR34","first-page":"e2840","volume":"10","author":"T Kassim","year":"2018","unstructured":"Kassim, T., Mahfood Haddad, T., Rakhra, A., et al. (2018). A case of amitriptyline-induced myocarditis. Cureus,10(6), e2840.","journal-title":"Cureus"},{"issue":"3\u20134","key":"9569_CR35","first-page":"223","volume":"26","author":"K Knudsen","year":"1988","unstructured":"Knudsen, K., Ricksten, S. E., & Heath, A. (1988). Clonidine interaction in amitriptyline poisoning. Journal of Toxicology: Clinical Toxicology,26(3\u20134), 223\u2013232.","journal-title":"Journal of Toxicology: Clinical Toxicology"},{"key":"9569_CR36","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1136\/emj.18.4.236","volume":"18","author":"GW Kerr","year":"2001","unstructured":"Kerr, G. W., McGuffie, A. C., & Wilkie, S. (2001). Tricyclic antidepressant overdose: A review. Emergency Medicine Journal,18, 236\u2013241. https:\/\/doi.org\/10.1136\/emj.18.4.236.","journal-title":"Emergency Medicine Journal"},{"key":"9569_CR37","doi-asserted-by":"publisher","first-page":"247","DOI":"10.4306\/pi.2008.5.4.247","volume":"5","author":"K Choi","year":"2008","unstructured":"Choi, K., & Lee, K. (2008). Serial monitoring of lead avr in patients with prolonged unconsciousness following tricyclic antidepressant overdose. Psychiatry Investigation,5, 247.","journal-title":"Psychiatry Investigation"},{"key":"9569_CR38","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1186\/s13104-017-2615-8","volume":"10","author":"K Sabah","year":"2017","unstructured":"Sabah, K., Chowdhury, A., Islam, M., Saha, B. P., Kabir, S. R., & Kawser, S. (2017). Amitriptyline-induced ventricular tachycardia: A case report. BMC Research Notes,10, 286.","journal-title":"BMC Research Notes"},{"key":"9569_CR39","first-page":"847","volume-title":"Goldfrank\u2019s Toxicology Emergencies","author":"EL Liebelt","year":"2002","unstructured":"Liebelt, E. L., & Francis, P. D. (2002). Cyclic antidepressants. In L. R. Goldfrank, N. M. Flomenbaum, N. A. Lewin, M. A. Howland, R. S. Hoffman, & L. S. Nelson (Eds.), Goldfrank\u2019s Toxicology Emergencies (7th ed., pp. 847\u2013864). USA: McGraw-Hill Companies.","edition":"7"},{"key":"9569_CR40","first-page":"295","volume":"11","author":"MH Nezafati","year":"2015","unstructured":"Nezafati, M. H., Vojdanparast, M., & Nezafati, P. (2015). Antidepressants and cardiovascular adverse events: A narrative review. ARYA Atheroscler.,11, 295\u2013304.","journal-title":"ARYA Atheroscler."},{"issue":"4","key":"9569_CR41","doi-asserted-by":"publisher","first-page":"1159","DOI":"10.1213\/ANE.0000000000002707","volume":"126","author":"S Tsujikawa","year":"2018","unstructured":"Tsujikawa, S., Matsuura, T., Hori, K., Mori, T., Kuno, M., & Nishikawa, K. (2018). Superior efficacy of lipid emulsion infusion over serum alkalinization in reversing amitriptyline-induced cardiotoxicity in Guinea Pig. Anesthesia & Analgesia,126(4), 1159\u20131169.","journal-title":"Anesthesia & Analgesia"},{"key":"9569_CR42","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1097\/MD.0b013e3181a4d1a1","volume":"88","author":"M Ben m\u2019rad","year":"2009","unstructured":"Ben m\u2019rad, M., Leclerc-Mercier, S., Blanche, P., et al. (2009). Drug-induced hypersensitivity syndrome: clinical and biologic disease patterns in 24 patients. Medicine (Baltimore),88, 131\u2013140.","journal-title":"Medicine (Baltimore)"},{"key":"9569_CR43","doi-asserted-by":"publisher","first-page":"205","DOI":"10.2165\/00139709-200524030-00013","volume":"24","author":"HK Thanacoody","year":"2005","unstructured":"Thanacoody, H. K., & Thomas, S. H. (2005). Tricyclic antidepressant poisoning. Toxicol Rev.,24, 205\u2013214. https:\/\/doi.org\/10.2165\/00139709-200524030-00013.","journal-title":"Toxicol Rev."},{"issue":"6","key":"9569_CR44","doi-asserted-by":"publisher","first-page":"525","DOI":"10.3325\/cmj.2015.56.525","volume":"56","author":"DO Yetkin","year":"2015","unstructured":"Yetkin, D. O., Kucukkaya, B., Turhan, M., & Oren, M. (2015). The effect of 25-hydroxyvitamin D levels on QT interval duration and dispersion in type 2 diabetic patients. Croat Med J.,56(6), 525\u2013530.","journal-title":"Croat Med J."},{"issue":"6","key":"9569_CR45","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1139\/cjpp-2016-0150","volume":"95","author":"OA El-Gohary","year":"2017","unstructured":"El-Gohary, O. A., & Allam, M. M. (2017). Effect of vitamin D on isoprenaline-induced myocardial infarction in rats: Possible role of peroxisome proliferator-activated receptor-\u03b3. Canadian Journal of Physiology and Pharmacology,95(6), 641\u2013646.","journal-title":"Canadian Journal of Physiology and Pharmacology"},{"key":"9569_CR46","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1016\/j.jsbmb.2015.09.034","volume":"164","author":"DJ Glenn","year":"2016","unstructured":"Glenn, D. J., Cardema, M. C., & Gardner, D. G. (2016). Amplification of lipotoxic cardiomyopathy in the VDR gene knockout mouse. J Steroid Biochem Mol Bio.,164, 292\u2013298.","journal-title":"J Steroid Biochem Mol Bio."},{"issue":"8s","key":"9569_CR47","first-page":"314","volume":"10","author":"S Taziki","year":"2013","unstructured":"Taziki, S., Sattari, M. R., & Egbal, M. A. (2013). Evaluation of amitriptyline-induced toxicity in freshly isolated rat hepatocytes and the protective role of taurine. Life Sci J.,10(8s), 314\u2013320.","journal-title":"Life Sci J."},{"issue":"3","key":"9569_CR48","doi-asserted-by":"publisher","first-page":"329","DOI":"10.15171\/apb.2015.046","volume":"5","author":"S Taziki","year":"2015","unstructured":"Taziki, S., Sattari, M. R., Dastmalchi, S., & Eghbal, M. A. (2015). Cytoprotective effects of melatonin against amitriptyline-induced toxicity in isolated rat hepatocytes. Adv Pharm Bull.,5(3), 329\u2013334.","journal-title":"Adv Pharm Bull."},{"key":"9569_CR49","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00232-005-0753-8","volume":"205","author":"G Stark","year":"2005","unstructured":"Stark, G. (2005). Functional consequences of oxidative membrane damage. Journal of Membrane Biology,205, 1\u201316.","journal-title":"Journal of Membrane Biology"},{"issue":"2\u20133","key":"9569_CR50","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1080\/15287398409530568","volume":"14","author":"D Acosta","year":"1984","unstructured":"Acosta, D., & Ramos, K. (1984). Cardiotoxicity of tricyclic antidepressants in primary cultures of rat myocardial cells. Journal of Toxicology and Environment Health,14(2\u20133), 137\u2013143.","journal-title":"Journal of Toxicology and Environment Health"},{"key":"9569_CR51","doi-asserted-by":"publisher","first-page":"1","DOI":"10.18621\/eurj.410029","volume":"5","author":"SS Gul","year":"2018","unstructured":"Gul, S. S., & Aygun, H. (2018). Cardioprotective effect of vitamin D and melatonin on doxorubicin-induced cardiotoxicity in rat model: an electrocardiographic, scintigraphic and biochemical study. The European Research Journal,5, 1\u20139. https:\/\/doi.org\/10.18621\/eurj.410029.","journal-title":"The European Research Journal"},{"issue":"Suppl 1","key":"9569_CR52","doi-asserted-by":"publisher","first-page":"S109","DOI":"10.3346\/jkms.2009.24.S1.S109","volume":"24","author":"SJ Hur","year":"2009","unstructured":"Hur, S. J., Kim, D. M., Lim, K. H., et al. (2009). Vitamin D levels and their relationship with cardiac biomarkers in chronic hemodialysis patients. Journal of Korean Medical Science,24(Suppl 1), S109\u2013S114.","journal-title":"Journal of Korean Medical Science"},{"issue":"1","key":"9569_CR53","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1186\/s12872-017-0597-z","volume":"17","author":"MA Farhangi","year":"2017","unstructured":"Farhangi, M. A., Nameni, G., Hajiluian, G., & Mesgari-Abbasi, M. (2017). Cardiac tissue oxidative stress and inflammation after vitamin D administrations in high fat-diet induced obese rats. BMC Cardiovasc Disord.,17(1), 161.","journal-title":"BMC Cardiovasc Disord."},{"issue":"8","key":"9569_CR54","first-page":"1366","volume":"35","author":"K Okuda","year":"1994","unstructured":"Okuda, K., Nohara, R., Fujita, M., et al. (1994). Technetium-99m-pyrophosphate uptake as an indicator of myocardial injury without infarct. Journal of Nuclear Medicine,35(8), 1366\u20131370.","journal-title":"Journal of Nuclear Medicine"},{"issue":"8","key":"9569_CR55","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1007\/BF02988634","volume":"16","author":"T Mochizuki","year":"2002","unstructured":"Mochizuki, T., Murase, K., Higashino, H., et al. (2002). Ischemic \"memory image\" in acute myocardial infarction of 123I-BMIPP after reperfusion therapy: A comparison with 99mTc-pyrophosphate and 201Tl dual-isotope SPECT. Annals of Nuclear Medicine,16(8), 563\u2013568.","journal-title":"Annals of Nuclear Medicine"},{"key":"9569_CR56","doi-asserted-by":"publisher","DOI":"10.1007\/s12350-018-1307-7","author":"AJ Einstein","year":"2018","unstructured":"Einstein, A. J., Shuryak, I., Castano, A., et al. (2018). Estimating cancer risk from 99mTc pyrophosphate imaging for transthyretin cardiac amyloidosis. Journal of Nuclear Cardiology.. https:\/\/doi.org\/10.1007\/s12350-018-1307-7.","journal-title":"Journal of Nuclear Cardiology."},{"issue":"6","key":"9569_CR57","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1016\/j.burns.2006.01.011","volume":"32","author":"KL Matthews","year":"2006","unstructured":"Matthews, K. L., Aarsvold, J. N., Mintzer, R. A., Chen, C. T., & Lee, R. C. (2006). Tc-99m pyrophosphate imaging of poloxamer-treated electroporated skeletal muscle in an in vivo rat model. Burns,32(6), 755\u2013764.","journal-title":"Burns"},{"issue":"7","key":"9569_CR58","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1007\/s10067-006-0463-3","volume":"26","author":"UA Walker","year":"2007","unstructured":"Walker, U. A., Garve, K., Brink, I., et al. (2007). 99mTechnetium pyrophosphate scintigraphy in the detection of skeletal muscle disease. Clinical Rheumatology,26(7), 1119\u20131122.","journal-title":"Clinical Rheumatology"},{"issue":"2","key":"9569_CR59","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1016\/j.jss.2015.09.006","volume":"200","author":"OD \u00c7ift\u00e7i","year":"2016","unstructured":"\u00c7ift\u00e7i, O. D., G\u00fcl, S. S., A\u00e7\u0131ksar\u0131, K., et al. (2016). The diagnostic utility of scintigraphy in esophageal burn: A rat model. Journal of Surgical Research,200(2), 495\u2013500.","journal-title":"Journal of Surgical Research"},{"issue":"Suppl","key":"9569_CR60","doi-asserted-by":"publisher","first-page":"1717S","DOI":"10.1093\/ajcn\/80.6.1717S","volume":"80","author":"MT Cantorna","year":"2004","unstructured":"Cantorna, M. T., Zhu, Y., Froicu, M., & Wittke, A. (1720S). Vitamin D status, 1\u201325- dihydroxyvitamin D3, and the immune system. American Journal of Clinical Nutrition,80(Suppl), 1717S\u20131720S.","journal-title":"American Journal of Clinical Nutrition"},{"key":"9569_CR61","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1002\/eji.200425491","volume":"35","author":"Y Zhu","year":"2005","unstructured":"Zhu, Y., Mahon, B. D., Froicu, M., & Cantorna, M. T. (2005). Calcium and 1 alpha,25-dihydroxyvitamin D3 target the TNF-alpha pathway to suppress experimental inflammatory bowel disease. European Journal of Immunology,35, 217\u2013224.","journal-title":"European Journal of Immunology"},{"key":"9569_CR62","doi-asserted-by":"publisher","first-page":"2061","DOI":"10.4049\/jimmunol.174.4.2061","volume":"174","author":"LA Lyakh","year":"2005","unstructured":"Lyakh, L. A., Sanford, M., Chekol, S., Young, H. A., & Roberts, A. B. (2005). TGF-beta and vitamin D3 utilize distinct pathways to suppress IL-12 production and modulate rapid differentiation of human monocytes into CD83 + dendritic cells. The Journal of Immunology,174, 2061\u20132070.","journal-title":"The Journal of Immunology"},{"key":"9569_CR63","doi-asserted-by":"publisher","first-page":"3780","DOI":"10.4049\/jimmunol.176.6.3780","volume":"176","author":"J Kong","year":"2006","unstructured":"Kong, J., Grando, S. A., & Li, Y. C. (2006). Regulation of IL-1 family cytokines IL-1%3e, IL-1 receptor antagonist, and IL-18 by 1,25-dihydroxyvitamin D3 in primary keratinocytes. The Journal of Immunology,176, 3780\u20133787.","journal-title":"The Journal of Immunology"},{"key":"9569_CR64","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/1471-2172-8-5","volume":"8","author":"M Froicu","year":"2007","unstructured":"Froicu, M., & Cantorna, M. T. (2007). Vitamin D and the vitamin D receptor are critical for control of the innate immune response to colonic injury. BMC Immunol.,8, 5.","journal-title":"BMC Immunol."},{"issue":"1","key":"9569_CR65","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1186\/1471-2369-13-159","volume":"13","author":"MJ Izquierdo","year":"2012","unstructured":"Izquierdo, M. J., Cavia, M., Mu\u00f1iz, P., de Francisco, A. L., Arias, M., Santos, J., et al. (2012). Paricalcitol reduces oxidative stress and inflammation in hemodialysis patients. BMC Nephrology,13(1), 159.","journal-title":"BMC Nephrology"},{"issue":"3","key":"9569_CR66","doi-asserted-by":"publisher","first-page":"209","DOI":"10.4331\/wjbc.v6.i3.209","volume":"6","author":"K Husain","year":"2015","unstructured":"Husain, K., Hernandez, W., Ansari, R. A., & Ferder, L. (2015). Inflammation, oxidative stress and renin angiotensin system in atherosclerosis. World Journal of Biological Chemistry,6(3), 209.","journal-title":"World Journal of Biological Chemistry"},{"issue":"6","key":"9569_CR67","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1177\/1753944714542593","volume":"8","author":"E Suarez-Martinez","year":"2014","unstructured":"Suarez-Martinez, E., Husain, K., & Ferder, L. (2014). Adiponectin expression and the cardioprotective role of the vitamin D receptor activator paricalcitol and the angiotensin converting enzyme inhibitor enalapril in ApoE-deficient mice. Therapeutic Advances in Cardiovascular Disease,8(6), 224\u2013236.","journal-title":"Therapeutic Advances in Cardiovascular Disease"},{"key":"9569_CR68","first-page":"310","volume-title":"Poisoning and Drug Overdose","author":"NL Benowitz","year":"1999","unstructured":"Benowitz, N. L. (1999). Tricylic antidepresants. In K. R. Olson (Ed.), Poisoning and Drug Overdose (3rd ed., pp. 310\u2013312). USA: Connecticut.","edition":"3"},{"issue":"2","key":"9569_CR69","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1081\/CLT-120004399","volume":"40","author":"Y Tuncok","year":"2002","unstructured":"Tuncok, Y., Kalkan, S., Murat, N., et al. (2002). The effect of the nitric oxide synthesis inhibitor L-NAME on amitriptyline-induced hypotension in rats. Journal of Toxicology\u2014Clinical Toxicology,40(2), 121\u2013127.","journal-title":"Journal of Toxicology\u2014Clinical Toxicology"},{"issue":"1","key":"9569_CR70","doi-asserted-by":"publisher","first-page":"F141","DOI":"10.1152\/ajprenal.00293.2011","volume":"302","author":"JL Finch","year":"2011","unstructured":"Finch, J. L., Suarez, E. B., Husain, K., Ferder, L., Cardema, M. C., Glenn, D. J., et al. (2011). Effect of combining an ACE inhibitor and a VDR activator on glomerulosclerosis, proteinuria, and renal oxidative stress in uremic rats. American Journal of Physiology\u2014Renal Physiology,302(1), F141\u2013F149.","journal-title":"American Journal of Physiology\u2014Renal Physiology"},{"issue":"3","key":"9569_CR71","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1124\/jpet.107.132456","volume":"324","author":"I Zahradn\u0131\u00b4k","year":"2008","unstructured":"Zahradn\u0131\u00b4k, I., Minarovic, I., & Zahradn\u0131\u00b4kova\u00b4, A. (2008). Inhibition of the cardiac L-type calcium channel current by antidepressant drugs. Journal of Pharmacology and Experimental Therapeutics,324(3), 977\u2013984.","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"key":"9569_CR72","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.jsbmb.2015.09.019","volume":"155","author":"WS Yang","year":"2016","unstructured":"Yang, W. S., Yu, H., Kim, J. J., Lee, M. J., & Park, S. K. (2016). Vitamin D-induced ectodomain shedding of TNF receptor 1 as a nongenomic action: D3 vs D2 derivatives. The Journal of Steroid Biochemistry and Molecular Biology,155, 18\u201325.","journal-title":"The Journal of Steroid Biochemistry and Molecular Biology"}],"container-title":["Cardiovascular Toxicology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12012-020-09569-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12012-020-09569-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12012-020-09569-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,26]],"date-time":"2021-03-26T00:16:41Z","timestamp":1616717801000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12012-020-09569-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,26]]},"references-count":72,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["9569"],"URL":"https:\/\/doi.org\/10.1007\/s12012-020-09569-3","relation":{},"ISSN":["1530-7905","1559-0259"],"issn-type":[{"value":"1530-7905","type":"print"},{"value":"1559-0259","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,26]]},"assertion":[{"value":"26 March 2020","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"No potential conflict of interest was reported by the authors.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}