{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T03:52:11Z","timestamp":1772596331640,"version":"3.50.1"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"9-10","license":[{"start":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T00:00:00Z","timestamp":1694044800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T00:00:00Z","timestamp":1694044800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cardiovasc Toxicol"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1007\/s12012-023-09804-7","type":"journal-article","created":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T05:02:06Z","timestamp":1694062926000},"page":"295-304","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Suberosin Alleviates Thiazolidinedione-Induced Cardiomyopathy in Diabetic Rats by Inhibiting Ferroptosis via Modulation of ACSL4-LPCAT3 and PI3K-AKT Signaling Pathways"],"prefix":"10.1007","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8414-5498","authenticated-orcid":false,"given":"Shabnoor","family":"Iqbal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farhat","family":"Jabeen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6440-3437","authenticated-orcid":false,"given":"Ivan","family":"Kahwa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0175-1055","authenticated-orcid":false,"given":"Timothy","family":"Omara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,9,7]]},"reference":[{"issue":"5","key":"9804_CR1","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.2337\/diacare.27.5.1047","volume":"27","author":"S Wild","year":"2004","unstructured":"Wild, S., Roglic, G., Green, A., Sicree, R., & King, H. (2004). Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care, 27(5), 1047\u20131053.","journal-title":"Diabetes Care"},{"key":"9804_CR2","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.991059","volume":"13","author":"V Sharma","year":"2022","unstructured":"Sharma, V., & Patial, V. (2022). Peroxisome proliferator-activated receptor gamma and its natural agonists in the treatment of kidney diseases. Frontiers in Pharmacology, 13, 991059.","journal-title":"Frontiers in Pharmacology"},{"issue":"5S","key":"9804_CR3","doi-asserted-by":"publisher","first-page":"S35","DOI":"10.1016\/j.jacc.2008.09.055","volume":"53","author":"G Orasanu","year":"2009","unstructured":"Orasanu, G., & Plutzky, J. (2009). The pathologic continuum of diabetic vascular disease. Journal of the American College of Cardiology, 53(5S), S35\u2013S42.","journal-title":"Journal of the American College of Cardiology"},{"key":"9804_CR4","doi-asserted-by":"publisher","first-page":"760","DOI":"10.1007\/s00125-003-1116-6","volume":"46","author":"S Laing","year":"2003","unstructured":"Laing, S. P., Swerdlow, A. J., Slater, S. D., Burden, A. C., Morris, A., Waugh, N. R., Gatling, W., Bingley, P. J., & Patterson, C. C. (2003). Mortality from heart disease in a cohort of 23,000 patients with insulin-treated diabetes. Diabetologia, 46, 760\u2013765.","journal-title":"Diabetologia"},{"key":"9804_CR5","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b2942","volume":"339","author":"DN Juurlink","year":"2009","unstructured":"Juurlink, D. N., Gomes, T., Lipscombe, L. L., Austin, P. C., Hux, J. E., & Mamdani, M. M. (2009). Adverse cardiovascular events during treatment with pioglitazone and rosiglitazone: Population based cohort study. BMJ, 339, b2942.","journal-title":"BMJ"},{"issue":"24","key":"9804_CR6","doi-asserted-by":"publisher","first-page":"2457","DOI":"10.1056\/NEJMoa072761","volume":"356","author":"SE Nissen","year":"2007","unstructured":"Nissen, S. E., & Wolski, K. (2007). Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. New England Journal of Medicine, 356(24), 2457\u20132471.","journal-title":"New England Journal of Medicine"},{"issue":"9593","key":"9804_CR7","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.1016\/S0140-6736(07)61514-1","volume":"370","author":"RM Lago","year":"2007","unstructured":"Lago, R. M., Singh, P. P., & Nesto, R. W. (2007). Congestive heart failure and cardiovascular death in patients with prediabetes and type 2 diabetes given thiazolidinediones: A meta-analysis of randomised clinical trials. The Lancet, 370(9593), 1129\u20131136.","journal-title":"The Lancet"},{"issue":"9","key":"9804_CR8","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1056\/NEJMp078167","volume":"357","author":"CJ Rosen","year":"2007","unstructured":"Rosen, C. J. (2007). The rosiglitazone story\u2014Lessons from an FDA Advisory Committee meeting. New England Journal of Medicine, 357(9), 844\u2013846.","journal-title":"New England Journal of Medicine"},{"issue":"2","key":"9804_CR9","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1124\/jpet.103.058008","volume":"308","author":"J Song","year":"2004","unstructured":"Song, J., Knepper, M. A., Hu, X., Verbalis, J. G., & Ecelbarger, C. A. (2004). Rosiglitazone activates renal sodium-and water-reabsorptive pathways and lowers blood pressure in normal rats. Journal of Pharmacology and Experimental Therapeutics, 308(2), 426\u2013433.","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"issue":"12","key":"9804_CR10","doi-asserted-by":"publisher","first-page":"3482","DOI":"10.1681\/ASN.2006060606","volume":"17","author":"J Karalliedde","year":"2006","unstructured":"Karalliedde, J., Buckingham, R., Starkie, M., Lorand, D., Stewart, M., Viberti, G., & Rosiglitazone Fluid Retention Study Group. (2006). Effect of various diuretic treatments on rosiglitazone-induced fluid retention. Journal of the American Society of Nephrology, 17(12), 3482\u20133490.","journal-title":"Journal of the American Society of Nephrology"},{"issue":"4","key":"9804_CR11","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1038\/clpt.2010.360","volume":"89","author":"A Rennings","year":"2011","unstructured":"Rennings, A. J., Russel, F. G., Li, Y., Deen, P. M., Masereeuw, R., Tack, C. J., & Smits, P. (2011). Preserved response to diuretics in rosiglitazone-treated subjects with insulin resistance: A randomized double-blind placebo-controlled crossover study. Clinical Pharmacology & Therapeutics, 89(4), 587\u2013594.","journal-title":"Clinical Pharmacology & Therapeutics"},{"key":"9804_CR12","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.911564","volume":"9","author":"Y Guo","year":"2022","unstructured":"Guo, Y., Zhang, W., Zhou, X., Zhao, S., Wang, J., Guo, Y., Liao, Y., Lu, H., Liu, J., Cai, Y., & Wu, J. (2022). Roles of ferroptosis in cardiovascular diseases. Front Cardiovasc Med, 9, 911564.","journal-title":"Front Cardiovasc Med"},{"issue":"1","key":"9804_CR13","doi-asserted-by":"publisher","first-page":"2136802","DOI":"10.1080\/08941939.2022.2136802","volume":"36","author":"S Karabulut Uzun\u00e7akmak","year":"2023","unstructured":"Karabulut Uzun\u00e7akmak, S., Hal\u0131c\u0131, Z., Karakaya, S., Kutlu, Z., Sa\u011flam, Y. S., Bolat, \u0130., Ayd\u0131n, P., & K\u0131l\u0131\u00e7, C. S. (2023). Suberosin alleviates sepsis-induced lung injury in a rat model of cecal ligation and puncture. Journal of InvestIgatIve surgery, 36(1), 2136802.","journal-title":"Journal of InvestIgatIve surgery"},{"issue":"01","key":"9804_CR14","doi-asserted-by":"publisher","first-page":"e15","DOI":"10.1055\/s-0035-1545936","volume":"2","author":"B-H Kim","year":"2015","unstructured":"Kim, B. H., Kwon, J., Lee, D., & Mar, W. (2015). Neuroprotective effect of demethylsuberosin, a proteasome activator, against MPP+-induced cell death in human neuroblastoma SH-SY5Y cells. Planta Medica Letters, 2(01), e15\u2013e18.","journal-title":"Planta Medica Letters"},{"issue":"1\u20132","key":"9804_CR15","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/j.cbi.2010.11.005","volume":"189","author":"RCR Latha","year":"2011","unstructured":"Latha, R. C. R., & Daisy, P. (2011). Insulin-secretagogue, antihyperlipidemic and other protective effects of gallic acid isolated from Terminalia bellerica Roxb. in streptozotocin-induced diabetic rats. Chemico-Biological Interactions, 189(1\u20132), 112\u2013118.","journal-title":"Chemico-Biological Interactions"},{"issue":"suppl 2","key":"9804_CR16","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1289\/ehp.98106497","volume":"106","author":"E Walum","year":"1998","unstructured":"Walum, E. (1998). Acute oral toxicity. Environmental Health Perspectives, 106(suppl 2), 497\u2013503.","journal-title":"Environmental Health Perspectives"},{"issue":"1","key":"9804_CR17","first-page":"1","volume":"46","author":"E Erdem Guzel","year":"2021","unstructured":"Erdem Guzel, E., Kaya Tektemur, N., Tektemur, A., & Etem \u00d6nalan, E. (2021). Carbamazepine-induced renal toxicity may be associated with oxidative stress and apoptosis in male rat. Drug and Chemical Toxicology, 46(1), 1\u20138.","journal-title":"Drug and Chemical Toxicology"},{"issue":"2","key":"9804_CR18","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1016\/j.ajpath.2013.10.020","volume":"184","author":"C-S Chang","year":"2014","unstructured":"Chang, C. S., Tsai, P. J., Sung, J. M., Chen, J. Y., Ho, L. C., Pandya, K., Maeda, N., & Tsai, Y. S. (2014). Diuretics prevent thiazolidinedione-induced cardiac hypertrophy without compromising insulin-sensitizing effects in mice. The American Journal of Pathology, 184(2), 442\u2013453.","journal-title":"The American Journal of Pathology"},{"issue":"2","key":"9804_CR19","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","volume":"95","author":"H Ohkawa","year":"1979","unstructured":"Ohkawa, H., Ohishi, N., & Yagi, K. (1979). Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Analytical Biochemistry, 95(2), 351\u2013358.","journal-title":"Analytical Biochemistry"},{"issue":"5","key":"9804_CR20","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1016\/S0894-7317(89)80014-8","volume":"2","author":"NB Schiller","year":"1989","unstructured":"Schiller, N. B., Shah, P. M., Crawford, M., DeMaria, A., Devereux, R., Feigenbaum, H., Gutgesell, H., Reichek, N., Sahn, D., Schnittger, I., & Silverman, N. H. (1989). Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. Journal of the American Society of Echocardiography, 2(5), 358\u2013367.","journal-title":"Journal of the American Society of Echocardiography"},{"key":"9804_CR21","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0041691","author":"C Benavides-Vallve","year":"2012","unstructured":"Benavides-Vallve, C., Corbacho, D., Iglesias-Garcia, O., Pelacho, B., Albiasu, E., Castano, S., Munoz-Barrutia, A., Prosper, F., & Ortiz-de-Solorzano, C. (2012). New strategies for echocardiographic evaluation of left ventricular function in a mouse model of long-term myocardial infarction. PLoS ONE. https:\/\/doi.org\/10.1371\/journal.pone.0041691","journal-title":"PLoS ONE"},{"key":"9804_CR22","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.jgar.2017.03.006","volume":"10","author":"S Bahari","year":"2017","unstructured":"Bahari, S., Zeighami, H., Mirshahabi, H., Roudashti, S., & Haghi, F. (2017). Inhibition of Pseudomonas aeruginosa quorum sensing by subinhibitory concentrations of curcumin with gentamicin and azithromycin. Journal of Global Antimicrobial Resistance, 10, 21\u201328.","journal-title":"Journal of Global Antimicrobial Resistance"},{"issue":"3","key":"9804_CR23","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1177\/1091581814526890","volume":"33","author":"A Mohammadi","year":"2014","unstructured":"Mohammadi, A., Mehrzad, J., Mahmoudi, M., & Schneider, M. (2014). Environmentally relevant level of aflatoxin B1 dysregulates human dendritic cells through signaling on key toll-like receptors. International Journal of Toxicology, 33(3), 175\u2013186.","journal-title":"International Journal of Toxicology"},{"key":"9804_CR24","doi-asserted-by":"crossref","unstructured":"Rassouli, A., Shihmani, B., Mehrzad, J., & Shokrpoor, S. (2022) The immunomodulatory effect of minocycline on gene expression of inflammation related cytokines in lipopolysaccharide-treated human peripheral blood mononuclear cells. Animal Biotechnology, 1\u20137.","DOI":"10.1080\/10495398.2022.2077743"},{"issue":"5","key":"9804_CR25","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1080\/10520290310001633725","volume":"78","author":"D Wittekind","year":"2003","unstructured":"Wittekind, D. (2003). Traditional staining for routine diagnostic pathology including the role of tannic acid. 1. Value and limitations of the hematoxylin-eosin stain. Biotechnic & Histochemistry, 78(5), 261\u2013270.","journal-title":"Biotechnic & Histochemistry"},{"issue":"10","key":"9804_CR26","doi-asserted-by":"publisher","first-page":"1335","DOI":"10.3109\/13880209.2014.892140","volume":"52","author":"F Golfakhrabadi","year":"2014","unstructured":"Golfakhrabadi, F., Abdollahi, M., Ardakani, M. R. S., Saeidnia, S., Akbarzadeh, T., Ahmadabadi, A. N., Ebrahimi, A., Yousefbeyk, F., Hassanzadeh, A., & Khanavi, M. (2014). Anticoagulant activity of isolated coumarins (suberosin and suberenol) and toxicity evaluation of Ferulago carduchorum in rats. Pharmaceutical Biology, 52(10), 1335\u20131340.","journal-title":"Pharmaceutical Biology"},{"issue":"11","key":"9804_CR27","doi-asserted-by":"publisher","first-page":"1527","DOI":"10.7863\/jum.2009.28.11.1527","volume":"28","author":"J Xu","year":"2009","unstructured":"Xu, J., Zhang, C., & Khanna, A. (2009). Wideband high-frequency echocardiography to evaluate myocardial infarct size. Journal of Ultrasound in Medicine, 28(11), 1527\u20131534.","journal-title":"Journal of Ultrasound in Medicine"},{"issue":"10","key":"9804_CR28","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1007\/s11745-012-3710-1","volume":"47","author":"F Zhou","year":"2012","unstructured":"Zhou, F., Zhong, W., Xue, J., Gu, Z. L., & Xie, M. L. (2012). Reduction of rat cardiac hypertrophy by osthol is related to regulation of cardiac oxidative stress and lipid metabolism. Lipids, 47(10), 987\u2013994.","journal-title":"Lipids"},{"key":"9804_CR29","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/646423","volume":"2015","author":"S Horita","year":"2015","unstructured":"Horita, S., Nakamura, M., Satoh, N., Suzuki, M., & Seki, G. (2015). Thiazolidinediones and edema: Recent advances in the pathogenesis of thiazolidinediones-induced renal sodium retention. PPAR Research, 2015, 646423.","journal-title":"PPAR Research"},{"issue":"4","key":"9804_CR30","doi-asserted-by":"publisher","first-page":"239","DOI":"10.4103\/0974-8490.89743","volume":"3","author":"SS Patel","year":"2011","unstructured":"Patel, S. S., & Goyal, R. K. (2011). Cardioprotective effects of gallic acid in diabetes-induced myocardial dysfunction in rats. Pharmacognosy research, 3(4), 239.","journal-title":"Pharmacognosy research"},{"issue":"8","key":"9804_CR31","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1016\/j.molmed.2019.05.012","volume":"25","author":"S Xu","year":"2019","unstructured":"Xu, S. (2019). Iron and atherosclerosis: The link revisited. Trends in Molecular Medicine, 25(8), 659\u2013661.","journal-title":"Trends in Molecular Medicine"},{"issue":"5","key":"9804_CR32","doi-asserted-by":"publisher","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","volume":"149","author":"SJ Dixon","year":"2012","unstructured":"Dixon, S. J., Lemberg, K. M., Lamprecht, M. R., Skouta, R., Zaitsev, E. M., Gleason, C. E., Patel, D. N., Bauer, A. J., Cantley, A. M., Yang, W. S., & Morrison, B. (2012). Ferroptosis: An iron-dependent form of nonapoptotic cell death. Cell, 149(5), 1060\u20131072.","journal-title":"Cell"},{"key":"9804_CR33","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2020.117334","volume":"247","author":"Z Hua","year":"2020","unstructured":"Hua, Z., Ma, K., Liu, S., Yue, Y., Cao, H., & Li, Z. (2020). LncRNA ZEB1-AS1 facilitates ox-LDL-induced damage of HCtAEC cells and the oxidative stress and inflammatory events of THP-1 cells via miR-942\/HMGB1 signaling. Life Sciences, 247, 117334.","journal-title":"Life Sciences"},{"issue":"2","key":"9804_CR34","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1002\/kjm2.12305","volume":"37","author":"RK Liang","year":"2021","unstructured":"Liang, R. K., Zhao, Y. Y., Shi, M. L., Zhang, G., Zhao, Y. J., Zhang, B. G., & Liang, R. J. (2021). Skimmin protects diabetic cardiomyopathy in streptozotocin-induced diabetic rats. Kaohsiung Journal of Medical Sciences, 37(2), 136\u2013144.","journal-title":"Kaohsiung Journal of Medical Sciences"},{"issue":"11\u201312","key":"9804_CR35","doi-asserted-by":"publisher","first-page":"2195","DOI":"10.1007\/s00018-016-2194-1","volume":"73","author":"JY Cao","year":"2016","unstructured":"Cao, J. Y., & Dixon, S. J. (2016). Mechanisms of ferroptosis. Cellular and Molecular Life Sciences, 73(11\u201312), 2195\u20132209.","journal-title":"Cellular and Molecular Life Sciences"},{"issue":"2","key":"9804_CR36","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/j.cell.2017.09.021","volume":"171","author":"BR Stockwell","year":"2017","unstructured":"Stockwell, B. R., Angeli, J. P. F., Bayir, H., Bush, A. I., Conrad, M., Dixon, S. J., Fulda, S., Gasc\u00f3n, S., Hatzios, S. K., Kagan, V. E., & Noel, K. (2017). Ferroptosis: A regulated cell death nexus linking metabolism, redox biology, and disease. Cell, 171(2), 273\u2013285.","journal-title":"Cell"},{"issue":"1","key":"9804_CR37","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1038\/nchembio.2239","volume":"13","author":"S Doll","year":"2017","unstructured":"Doll, S., Proneth, B., Tyurina, Y.Y., Panzilius, E., Kobayashi, S., Ingold, I., Irmler, M., Beckers, J., Aichler, M., Walch, A., & Prokisch, H., (2017). ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition. Nature Chemical Biology, 13(1), 91\u201398.","journal-title":"Nature Chemical Biology"},{"key":"9804_CR38","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.plipres.2018.11.001","volume":"73","author":"NK Singh","year":"2019","unstructured":"Singh, N. K., & Rao, G. N. (2019). Emerging role of 12\/15-Lipoxygenase (ALOX15) in human pathologies. Progress in Lipid Research, 73, 28\u201345.","journal-title":"Progress in Lipid Research"},{"issue":"51","key":"9804_CR39","doi-asserted-by":"publisher","first-page":"17835","DOI":"10.1021\/jacs.8b09913","volume":"140","author":"TS Anthonymuthu","year":"2018","unstructured":"Anthonymuthu, T. S., Kenny, E. M., Shrivastava, I., Tyurina, Y. Y., Hier, Z. E., Ting, H. C., Dar, H. H., Tyurin, V. A., Nesterova, A., Amoscato, A. A., & Mikulska-Ruminska, K. (2018). Empowerment of 15-lipoxygenase catalytic competence in selective oxidation of membrane ETE-PE to ferroptotic death signals, HpETE-PE. Journal of the American Chemical Society, 140(51), 17835\u201317839.","journal-title":"Journal of the American Chemical Society"},{"issue":"7","key":"9804_CR40","doi-asserted-by":"publisher","first-page":"1604","DOI":"10.1021\/acschembio.5b00245","volume":"10","author":"SJ Dixon","year":"2015","unstructured":"Dixon, S. J., Winter, G. E., Musavi, L. S., Lee, E. D., Snijder, B., Rebsamen, M., Superti-Furga, G., & Stockwell, B. R. (2015). Human haploid cell genetics reveals roles for lipid metabolism genes in nonapoptotic cell death. ACS Chemical Biology, 10(7), 1604\u20131609.","journal-title":"ACS Chemical Biology"},{"issue":"6","key":"9804_CR41","doi-asserted-by":"publisher","first-page":"1519","DOI":"10.1053\/j.gastro.2015.07.012","volume":"149","author":"Z Li","year":"2015","unstructured":"Li, Z., Jiang, H., Ding, T., Lou, C., Bui, H. H., Kuo, M. S., & Jiang, X. C. (2015). Deficiency in lysophosphatidylcholine acyltransferase 3 reduces plasma levels of lipids by reducing lipid absorption in mice. Gastroenterology, 149(6), 1519\u20131529.","journal-title":"Gastroenterology"},{"key":"9804_CR42","doi-asserted-by":"publisher","first-page":"431","DOI":"10.2147\/DDDT.S126964","volume":"11","author":"C Yang","year":"2017","unstructured":"Yang, C., Ma, X., Wang, Z., Zeng, X., Hu, Z., Ye, Z., & Shen, G. (2017). Curcumin induces apoptosis and protective autophagy in castration-resistant prostate cancer cells through iron chelation. Drug Design, Development and Therapy, 11, 431\u2013439.","journal-title":"Drug Design, Development and Therapy"},{"key":"9804_CR43","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1016\/j.cbi.2015.11.003","volume":"242","author":"MR de Oliveira","year":"2015","unstructured":"de Oliveira, M. R., Ferreira, G. C., Schuck, P. F., & Dal Bosco, S. M. (2015). Role for the PI3K\/Akt\/Nrf2 signaling pathway in the protective effects of carnosic acid against methylglyoxal-induced neurotoxicity in SH-SY5Y neuroblastoma cells. Chemico-Biological Interactions, 242, 396\u2013406.","journal-title":"Chemico-Biological Interactions"}],"container-title":["Cardiovascular Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12012-023-09804-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12012-023-09804-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12012-023-09804-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,21]],"date-time":"2023-09-21T01:08:43Z","timestamp":1695258523000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12012-023-09804-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,7]]},"references-count":43,"journal-issue":{"issue":"9-10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["9804"],"URL":"https:\/\/doi.org\/10.1007\/s12012-023-09804-7","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-3061810\/v1","asserted-by":"object"}]},"ISSN":["1530-7905","1559-0259"],"issn-type":[{"value":"1530-7905","type":"print"},{"value":"1559-0259","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,7]]},"assertion":[{"value":"21 June 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 August 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 September 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The author declares no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The animal handling and treatment experimental protocols underwent review and monitoring by the ethical committee of the Government College University, Faisalabad, Pakistan. These protocols followed the approved protocol of the European Union of animal care and Experimentation (CEE Council 86\/609). The research was conducted in adherence to the ARRIVE guidelines.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}