{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T13:54:49Z","timestamp":1789998889857,"version":"4.0.1"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T00:00:00Z","timestamp":1713139200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T00:00:00Z","timestamp":1713139200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Bilecik Seyh Edebali University"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cardiovasc Toxicol"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Inflammation plays a key role in the pathogenesis of the coronary slow flow phenomenon (CSFP). The newly developed inflammatory marker, pan-immune-inflammation value (PIV), is associated with adverse cardiovascular events. This study investigated the predictive value of PIV for diagnosing CSFP in comparison to other inflammation-based markers. A total of 214 patients, 109 in the CSFP group and 105 in the normal coronary flow (NCF) group, were retrospectively included in the study. Coronary flow was calculated using the Thrombolysis in Myocardial Infarction frame count method. In addition to PIV, other inflammatory markers such as neutrophil\u2013lymphocyte ratio, platelet-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII) were calculated for the patients. The average age of patients was 50.3\u2009\u00b1\u20098.4, with a male ratio of 55.1%. Compared to the NCF group, patients in the CSFP group had higher levels of hyperlipidemia, glucose, triglyceride, NLR, PLR, SII, and PIV, while their high-density lipoprotein cholesterol (HDL-C), was lower (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Logistic regression analysis demonstrated that HDL-C, glucose, triglyceride, and PIV were independent predictor factors for CSFP (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). PIV is a strong and independent predictor factor for CSFP and superior in predicting CSFP compared to other inflammatory markers.<\/jats:p>","DOI":"10.1007\/s12012-024-09855-4","type":"journal-article","created":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T19:02:06Z","timestamp":1713207726000},"page":"519-526","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Could Pan-Immune-Inflammation Value be a Marker for the Diagnosis of Coronary Slow Flow Phenomenon?"],"prefix":"10.1007","volume":"24","author":[{"given":"Mustafa","family":"Kaplangoray","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenan","family":"Toprak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edhem","family":"Deveci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cuneyt","family":"Caglayan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebru","family":"\u015eahin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,15]]},"reference":[{"key":"9855_CR1","doi-asserted-by":"publisher","first-page":"818","DOI":"10.1253\/circj.CJ-12-0205","volume":"76","author":"JF Beltrame","year":"2012","unstructured":"Beltrame, J. F. (2012). Defining the coronary slow flow phenomenon. Circulation Journal, 76, 818\u2013820.","journal-title":"Circulation Journal"},{"key":"9855_CR2","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/0002-8703(72)90307-9","volume":"84","author":"AA Tambe","year":"1972","unstructured":"Tambe, A. A., Demany, M. A., Zimmerman, H. A., & Mascarenhas, E. (1972). Angina pectoris and slow flow velocity of dye in coronary arteries\u2014A new angiographic finding. American Heart Journal, 84, 66\u201371.","journal-title":"American Heart Journal"},{"key":"9855_CR3","first-page":"7941","volume":"25","author":"L Askin","year":"2021","unstructured":"Askin, L. (2021). Evaluation of heart rate recovery index in patients with coronary slow flow: Preliminary results. European Review for Medical and Pharmacological Sciences, 25, 7941\u20137946.","journal-title":"European Review for Medical and Pharmacological Sciences"},{"key":"9855_CR4","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1177\/00033197211004390","volume":"72","author":"G Chalikias","year":"2021","unstructured":"Chalikias, G., & Tziakas, D. (2021). Slow coronary flow: Pathophysiology, clinical implications, and therapeutic management. Angiology, 72, 808\u2013818.","journal-title":"Angiology"},{"key":"9855_CR5","doi-asserted-by":"publisher","first-page":"964","DOI":"10.1161\/01.CIR.74.5.964","volume":"74","author":"M Mosseri","year":"1986","unstructured":"Mosseri, M., Yarom, R., Gotsman, M. S., & Hasin, Y. (1986). Histologic evidence for small-vessel coronary artery disease in patients with angina pectoris and patent large coronary arteries. Circulation, 74, 964\u2013972.","journal-title":"Circulation"},{"key":"9855_CR6","doi-asserted-by":"publisher","DOI":"10.1097\/00019501-200304000-00008","author":"AT Sezgin","year":"2003","unstructured":"Sezgin, A. T., Sgrc, A., Barutcu, I., Topal, E., Sezgin, N., Ozdemir, R., Yetkin, E., Tandogan, I., Kosar, F., Ermis, N., Yologlu, S., Barskaner, E., & Cehreli, S. (2003). Vascular endothelial function in patients with slow coronary flow. Coronary Artery Disease. https:\/\/doi.org\/10.1097\/00019501-200304000-00008","journal-title":"Coronary Artery Disease"},{"key":"9855_CR7","doi-asserted-by":"publisher","first-page":"463","DOI":"10.5543\/tkda.2011.01578","volume":"39","author":"N Kalay","year":"2011","unstructured":"Kalay, N., Aytekin, M., Kaya, M. G., Ozbek, K., Karayakal\u0131, M., S\u00f6\u011f\u00fct, E., Altunkas, F., Ozt\u00fcrk, A., & Ko\u00e7, F. (2011). The relationship between inflammation and slow coronary flow: Increased red cell distribution width and serum uric acid levels. T\u00fcrk Kardiyoloji Dernegi Arsivi, 39, 463\u2013468.","journal-title":"T\u00fcrk Kardiyoloji Dernegi Arsivi"},{"key":"9855_CR8","doi-asserted-by":"publisher","DOI":"10.1097\/MCA.0b013e3282f0a2a7","author":"A Yildiz","year":"2007","unstructured":"Yildiz, A., Yilmaz, R., Demirbag, R., Gur, M., Bas, M. M., & Erel, O. (2007). Association of serum uric acid level and coronary blood flow. Coronary Artery Disease. https:\/\/doi.org\/10.1097\/MCA.0b013e3282f0a2a7","journal-title":"Coronary Artery Disease"},{"key":"9855_CR9","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.ijcard.2003.06.025","volume":"97","author":"H Pekdemir","year":"2004","unstructured":"Pekdemir, H., Polat, G., Cin, V. G., \u00c7amsari, A., Cicek, D., Akkus, M. N., Doven, O., Katircibas\u0131, M. T., & Muslu, N. (2004). Elevated plasma endothelin-1 levels in coronary sinus during rapid right atrial pacing in patients with slow coronary flow. International Journal of Cardiology, 97, 35\u201341.","journal-title":"International Journal of Cardiology"},{"key":"9855_CR10","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.ejrad.2009.07.002","volume":"77","author":"M Kantarci","year":"2011","unstructured":"Kantarci, M., G\u00fcndogdu, F., Doganay, S., Duran, C., Kalkan, M. E., Sagsoz, M. E., Kucuk, O., Karakaya, A., Kucuk, A., & Akg\u00fcn, M. (2011). Arterial bending angle and wall morphology correlate with slow coronary flow: Determination with multidetector CT coronary angiography. European Journal of Radiology, 77, 111\u2013117.","journal-title":"European Journal of Radiology"},{"key":"9855_CR11","first-page":"117","volume":"4","author":"L A\u015fk\u0131n","year":"2018","unstructured":"A\u015fk\u0131n, L., \u00c7etin, M., T\u00fcrkmen, S., Tasolar, M. H., & Akt\u00fcrk, E. (2018). Quantitative ultrasound measurements of common carotid artery blood flow velocity patterns in patients with coronary slow flow. Journal of Human Rhythm, 4, 117\u2013125.","journal-title":"Journal of Human Rhythm"},{"key":"9855_CR12","doi-asserted-by":"publisher","first-page":"274","DOI":"10.2174\/1573403X15666190225123544","volume":"15","author":"JG de Moura Monteiro J\u00fanior","year":"2019","unstructured":"de Moura Monteiro J\u00fanior, J. G., de Oliveira Cipriano Torres, D., & Filho, D. C. S. (2019). Hematological parameters as prognostic biomarkers in patients with cardiovascular diseases. Current Cardiology Reviews, 15, 274\u2013282.","journal-title":"Current Cardiology Reviews"},{"key":"9855_CR13","first-page":"307","volume":"32","author":"M \u00c7etin","year":"2016","unstructured":"\u00c7etin, M., Kiziltunc, E., Elalm\u0131\u015f, \u00d6. U., \u00c7etin, Z. G., Demir\u00e7elik, M. B., \u00c7i\u00e7ek\u00e7io\u011flu, H., Kurtul, A., \u00d6zkan, S., Avan, C. M., \u00d6rnek, E., & Ulusoy, F. V. (2016). Predictive value of neutrophil lymphocyte ratio and platelet lymphocyte ratio in patients with coronary slow flow. Acta Cardiological Sinica, 32, 307\u2013312.","journal-title":"Acta Cardiological Sinica"},{"key":"9855_CR14","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1159\/000336948","volume":"121","author":"V Kopetz","year":"2012","unstructured":"Kopetz, V., Kennedy, J., Heresztyn, T., Stafford, I., Willoughby, S. R., & Beltrame, J. F. (2012). Endothelial function, oxidative stress and inflammatory studies in chronic coronary slow flow phenomenon patients. Cardiology, 121, 197\u2013203.","journal-title":"Cardiology"},{"key":"9855_CR15","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241814378","author":"B-S Tudurachi","year":"2023","unstructured":"Tudurachi, B.-S., Anghel, L., Tudurachi, A., Sasc\u0103u, R. A., & St\u0103tescu, C. (2023). Assessment of inflammatory hematological ratios (NLR, PLR, MLR, LMR and monocyte\/HDL\u2013cholesterol ratio) in acute myocardial infarction and particularities in young patients. International Journal of Molecular Sciences. https:\/\/doi.org\/10.3390\/ijms241814378","journal-title":"International Journal of Molecular Sciences"},{"key":"9855_CR16","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14112675","author":"DC Guven","year":"2022","unstructured":"Guven, D. C., Sahin, T. K., Erul, E., Kilickap, S., Gambichler, T., & Aksoy, S. (2022). The association between the pan-immune-inflammation value and cancer prognosis: A systematic review and meta-analysis. Cancers. https:\/\/doi.org\/10.3390\/cancers14112675","journal-title":"Cancers"},{"key":"9855_CR17","doi-asserted-by":"publisher","DOI":"10.1111\/eci.13872","volume":"53","author":"B Murat","year":"2023","unstructured":"Murat, B., Murat, S., Ozgeyik, M., & Bilgin, M. (2023). Comparison of pan-immune-inflammation value with other inflammation markers of long-term survival after ST-segment elevation myocardial infarction. European Journal of Clinical Investigation, 53, e13872.","journal-title":"European Journal of Clinical Investigation"},{"key":"9855_CR18","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1080\/00365513.2023.2241131","volume":"83","author":"A Bayramo\u011flu","year":"2023","unstructured":"Bayramo\u011flu, A., & Hidayet, \u015e. (2023). Association between pan-immune-inflammation value and no-reflow in patients with ST elevation myocardial infarction undergoing percutaneous coronary intervention. Scandinavian Journal of Clinical and Laboratory Investigation, 83, 384\u2013389.","journal-title":"Scandinavian Journal of Clinical and Laboratory Investigation"},{"key":"9855_CR19","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1161\/01.CIR.93.5.879","volume":"93","author":"CM Gibson","year":"1996","unstructured":"Gibson, C. M., Cannon, C. P., Daley, W. L., Dodge, J. T., Alexander, B., Marble, S. J., McCabe, C. H., Raymond, L., Fortin, T., Poole, W. K., & Braunwald, E. (1996). TIMI frame count. Circulation, 93, 879\u2013888.","journal-title":"Circulation"},{"key":"9855_CR20","doi-asserted-by":"publisher","DOI":"10.1177\/1076029619835383","author":"O Kayapinar","year":"2019","unstructured":"Kayapinar, O., Ozde, C., & Kaya, A. (2019). Relationship between the reciprocal change in inflammation-related biomarkers (fibrinogen-to-albumin and hsCRP-to-albumin ratios) and the presence and severity of coronary slow flow. Clinical and Applied Thrombosis\/Hemostasis. https:\/\/doi.org\/10.1177\/1076029619835383","journal-title":"Clinical and Applied Thrombosis\/Hemostasis"},{"key":"9855_CR21","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1586\/erc.12.159","volume":"11","author":"T Bhat","year":"2013","unstructured":"Bhat, T., Teli, S., Rijal, J., Bhat, H., Raza, M., Khoueiry, G., Meghani, M., Akhtar, M., & Costantino, T. (2013). Neutrophil to lymphocyte ratio and cardiovascular diseases: A review. Expert Review of Cardiovascular Therapy, 11, 55\u201359.","journal-title":"Expert Review of Cardiovascular Therapy"},{"key":"9855_CR22","doi-asserted-by":"publisher","DOI":"10.36660\/abc.20220679","author":"M Kaplangoray","year":"2023","unstructured":"Kaplangoray, M., Toprak, K., Ba\u015fanalan, F., Palice, A., Ayd\u0131n, C., Demirk\u0131ran, A., & Cekici, Y. (2023). Investiga\u00e7\u00e3o da Rela\u00e7\u00e3o entre \u00cdndice de Triglicer\u00eddeos-Glicose e Fluxo Lento Coronariano Um Estudo Retrospectivo de Caso-Controle. Arquivos Brasileiros de Cardiologia. https:\/\/doi.org\/10.36660\/abc.20220679","journal-title":"Arquivos Brasileiros de Cardiologia"},{"key":"9855_CR23","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1186\/s12872-022-02798-0","volume":"22","author":"X-T Dai","year":"2022","unstructured":"Dai, X.-T., Kong, T.-Z., Zhang, X.-J., Luan, B., Wang, Y., & Hou, A.-J. (2022). Relationship between increased systemic immune-inflammation index and coronary slow flow phenomenon. BMC Cardiovascular Disorders, 22, 362.","journal-title":"BMC Cardiovascular Disorders"},{"key":"9855_CR24","doi-asserted-by":"publisher","first-page":"2471","DOI":"10.1007\/s00405-022-07804-x","volume":"280","author":"DC Guven","year":"2023","unstructured":"Guven, D. C., Erul, E., Yilmaz, F., Yasar, S., Yildirim, H. C., Ercan, F., Kaygusuz, Y., Cayiroz, K., Ucdal, M. T., Yesil, F., Yazici, G., Cengiz, M., Gullu, I., & Aksoy, S. (2023). The association between pan-immune-inflammation value and survival in head and neck squamous cell carcinoma. European Archives of Oto-Rhino-Laryngology, 280, 2471\u20132478.","journal-title":"European Archives of Oto-Rhino-Laryngology"},{"key":"9855_CR25","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15010322","author":"C-C Yeh","year":"2023","unstructured":"Yeh, C.-C., Kao, H.-K., Huang, Y., Tsai, T.-Y., Young, C.-K., Hung, S.-Y., Lu, C.-Y., & Chang, K.-P. (2023). Discovering the clinical and prognostic role of pan-immune-inflammation values on oral cavity squamous cell carcinoma. Cancers. https:\/\/doi.org\/10.3390\/cancers15010322","journal-title":"Cancers"},{"key":"9855_CR26","doi-asserted-by":"publisher","first-page":"2158103","DOI":"10.1080\/0886022X.2022.2158103","volume":"45","author":"F Zhang","year":"2023","unstructured":"Zhang, F., Li, L., Wu, X., Wen, Y., Zhan, X., Peng, F., Wang, X., Zhou, Q., & Feng, X. (2023). Pan-immune-inflammation value is associated with poor prognosis in patients undergoing peritoneal dialysis. Renal Failure, 45, 2158103.","journal-title":"Renal Failure"},{"key":"9855_CR27","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1038\/nrcardio.2016.185","volume":"14","author":"N Ruparelia","year":"2017","unstructured":"Ruparelia, N., Chai, J. T., Fisher, E. A., & Choudhury, R. P. (2017). Inflammatory processes in cardiovascular disease: A route to targeted therapies. Nature Reviews Cardiology, 14, 133\u2013144.","journal-title":"Nature Reviews Cardiology"},{"key":"9855_CR28","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2023.131631","volume":"398","author":"S Akkaya","year":"2024","unstructured":"Akkaya, S., & Cakmak, U. (2024). Association between pan-immune-inflammation value and coronary slow flow phenomenon in patients with angiographically normal coronary arteries. International Journal of Cardiology, 398, 131631.","journal-title":"International Journal of Cardiology"},{"key":"9855_CR29","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13051295","author":"Z Cetinkaya","year":"2024","unstructured":"Cetinkaya, Z., Kelesoglu, S., Tuncay, A., Yilmaz, Y., Karaca, Y., Karasu, M., Secen, O., Cinar, A., Harman, M., Sahin, S., Akin, Y., & Yavcin, O. (2024). The role of pan-immune-inflammation value in determining the severity of coronary artery disease in NSTEMI patients. Journal of Clinical Medicine. https:\/\/doi.org\/10.3390\/jcm13051295","journal-title":"Journal of Clinical Medicine"},{"key":"9855_CR30","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1186\/s12872-021-02432-5","volume":"21","author":"A Afsin","year":"2021","unstructured":"Afsin, A., Kaya, H., Suner, A., Uzel, K. E., Bursa, N., Hosoglu, Y., Yavuz, F., & Asoglu, R. (2021). Plasma atherogenic indices are independent predictors of slow coronary flow. BMC Cardiovascular Disorders, 21, 608.","journal-title":"BMC Cardiovascular Disorders"},{"key":"9855_CR31","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1194\/jlr.P011668","volume":"52","author":"M Dobi\u00e1\u0161ov\u00e1","year":"2011","unstructured":"Dobi\u00e1\u0161ov\u00e1, M., Frohlich, J., \u0160edov\u00e1, M., Cheung, M. C., & Brown, B. G. (2011). Cholesterol esterification and atherogenic index of plasma correlate with lipoprotein size and findings on coronary angiography. Journal of Lipid Research, 52, 566\u2013571.","journal-title":"Journal of Lipid Research"},{"key":"9855_CR32","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1007\/s10554-021-02387-w","volume":"38","author":"G Aciksari","year":"2022","unstructured":"Aciksari, G., Cetinkal, G., Kocak, M., Atici, A., Celik, F. B., & Caliskan, M. (2022). The relationship between triglyceride\/high-density lipoprotein cholesterol ratio and coronary slow-flow phenomenon. The International Journal of Cardiovascular Imaging, 38, 5\u201313.","journal-title":"The International Journal of Cardiovascular Imaging"},{"key":"9855_CR33","doi-asserted-by":"publisher","DOI":"10.5812\/cardiovascmed.30296","author":"H Sanati","year":"2016","unstructured":"Sanati, H., Kiani, R., Shakerian, F., Firouzi, A., Zahedmehr, A., Peighambari, M., Shokrian, L., & Ashrafi, P. (2016). Coronary slow flow phenomenon: Clinical findings and predictors. Research in Cardiovascular Medicine. https:\/\/doi.org\/10.5812\/cardiovascmed.30296","journal-title":"Research in Cardiovascular Medicine"},{"key":"9855_CR34","doi-asserted-by":"publisher","first-page":"23","DOI":"10.5334\/gh.1111","volume":"17","author":"M Khalfallah","year":"2022","unstructured":"Khalfallah, M., Maria, D. A., & Allaithy, A. (2022). Impact of stress hyperglycemia on no-reflow phenomenon in patients with ST elevation myocardial infarction undergoing primary percutaneous coronary intervention. Global Heart, 17, 23.","journal-title":"Global Heart"},{"key":"9855_CR35","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/S0735-1097(99)00168-0","volume":"34","author":"H Kawano","year":"1999","unstructured":"Kawano, H., Motoyama, T., Hirashima, O., Hirai, N., Miyao, Y., Sakamoto, T., Kugiyama, K., Ogawa, H., & Yasue, H. (1999). Hyperglycemia rapidly suppresses flow-mediated endothelium\u2014Dependent vasodilation of brachial artery. Journal of the American College of Cardiology, 34, 146\u2013154.","journal-title":"Journal of the American College of Cardiology"},{"key":"9855_CR36","doi-asserted-by":"publisher","first-page":"2055","DOI":"10.2337\/diacare.22.12.2055","volume":"22","author":"S Vehkavaara","year":"1999","unstructured":"Vehkavaara, S., Sepp\u00e4l\u00e4-Lindroos, A., Westerbacka, J., Groop, P. H., & Yki-J\u00e4rvinen, H. (1999). In vivo endothelial dysfunction characterizes patients with impaired fasting glucose. Diabetes Care, 22, 2055\u20132060.","journal-title":"Diabetes Care"},{"key":"9855_CR37","doi-asserted-by":"publisher","first-page":"2111","DOI":"10.2337\/diacare.21.12.2111","volume":"21","author":"E Anastasiou","year":"1998","unstructured":"Anastasiou, E., Lekakis, J. P., Alevizaki, M., Papamichael, C. M., Megas, J., Souvatzoglou, A., & Stamatelopoulos, S. F. (1998). Impaired endothelium-dependent vasodilatation in women with previous gestational diabetes. Diabetes Care, 21, 2111\u20132115.","journal-title":"Diabetes Care"},{"key":"9855_CR38","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.ijcard.2005.09.007","volume":"111","author":"E Binak","year":"2006","unstructured":"Binak, E., Gunduz, H., Sahin, M., Kurtoglu, N., & Dindar, I. (2006). The relation between impaired glucose tolerance and slow coronary flow. International Journal of Cardiology, 111, 142\u2013146.","journal-title":"International Journal of Cardiology"},{"key":"9855_CR39","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1007\/s00380-010-0081-5","volume":"26","author":"S Xia","year":"2011","unstructured":"Xia, S., Deng, S.-B., Wang, Y., Xiao, J., Du, J.-L., Zhang, Y., Wang, X.-C., Li, Y.-Q., Zhao, R., He, L., Xiang, Y.-L., & She, Q. (2011). Clinical analysis of the risk factors of slow coronary flow. Heart and Vessels, 26, 480\u2013486.","journal-title":"Heart and Vessels"}],"container-title":["Cardiovascular Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12012-024-09855-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12012-024-09855-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12012-024-09855-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T15:10:15Z","timestamp":1715094615000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12012-024-09855-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,15]]},"references-count":39,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["9855"],"URL":"https:\/\/doi.org\/10.1007\/s12012-024-09855-4","relation":{},"ISSN":["1530-7905","1559-0259"],"issn-type":[{"value":"1530-7905","type":"print"},{"value":"1559-0259","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,15]]},"assertion":[{"value":"9 January 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 March 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 April 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no confict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was conducted by the Helsinki Declaration and was approved by the ethics committee of Bilecik Seyh Edebali University Faculty of Medicine.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"The authors give their consent for the publication of this manuscript.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}}]}}