{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T03:07:47Z","timestamp":1790564867579,"version":"4.1.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T00:00:00Z","timestamp":1779753600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T00:00:00Z","timestamp":1779753600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Japanese Circulation Society Grant for Medical Staff for Clinical Research"},{"name":"JSPS KAKENHI","award":["23K07518"],"award-info":[{"award-number":["23K07518"]}]},{"name":"National Cancer Center Research and Development Fund","award":["2023-A-12"],"award-info":[{"award-number":["2023-A-12"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cardiovasc Toxicol"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1007\/s12012-026-10133-8","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T10:53:24Z","timestamp":1779792804000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinical Characteristics and Outcomes of Heart Failure with Preserved Ejection Fraction Versus Reduced Ejection Fraction in Patients Receiving Anticancer Drugs"],"prefix":"10.1007","volume":"26","author":[{"given":"Yuma","family":"Shibutani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuka","family":"Aoki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuro","family":"Imaoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsuko","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuko","family":"Tajiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,26]]},"reference":[{"issue":"3","key":"10133_CR1","doi-asserted-by":"publisher","first-page":"229","DOI":"10.3322\/caac.21834","volume":"74","author":"F Bray","year":"2024","unstructured":"Bray, F., Laversanne, M., Sung, H., Ferlay, J., Siegel, R. L., Soerjomataram, I., & Jemal, A. (2024). Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 74(3), 229\u2013263. https:\/\/doi.org\/10.3322\/caac.21834","journal-title":"CA: A Cancer Journal for Clinicians"},{"key":"10133_CR2","doi-asserted-by":"publisher","first-page":"1634","DOI":"10.1002\/cncr.34743","volume":"129","author":"A Desai","year":"2023","unstructured":"Desai, A., Reddy, N. K., & Subbiah, V. (2023). Top advances of the year: Precision oncology. Cancer, 129, 1634\u20131642. https:\/\/doi.org\/10.1002\/cncr.34743","journal-title":"Cancer"},{"issue":"36","key":"10133_CR3","doi-asserted-by":"publisher","first-page":"2768","DOI":"10.1002\/ejhf.654","volume":"37","author":"JL Zamorano","year":"2016","unstructured":"Zamorano, J. L., Lancellotti, P., Rodriguez Mu\u00f1oz, D., Aboyans, V., Asteggiano, R., Galderisi, M., Habib, G., Lenihan, D. J., Lip, G. Y., Lyon, A. R., & Lopez Fernandez, T. (2016). 2016 ESC position paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC committee for practice guidelines: The task force for cancer treatments and cardiovascular toxicity of the European society of cardiology (ESC). European Heart Journal, 37(36), 2768\u20132801. https:\/\/doi.org\/10.1002\/ejhf.654","journal-title":"European Heart Journal"},{"key":"10133_CR4","doi-asserted-by":"publisher","first-page":"117954681986644","DOI":"10.1177\/1179546819866445","volume":"13","author":"IE Perez","year":"2019","unstructured":"Perez, I. E., Taveras Alam, S., Hernandez, G. A., & Sancassani, R. (2019). Cancer therapy-related cardiac dysfunction: An overview for the clinician. Clinical Medicine Insights: Cardiology, 13, 1179546819866445. https:\/\/doi.org\/10.1177\/1179546819866445","journal-title":"Clinical Medicine Insights: Cardiology"},{"issue":"17","key":"10133_CR5","doi-asserted-by":"publisher","first-page":"e263","DOI":"10.1161\/CIR.0000000000001063","volume":"79","author":"PA Heidenreich","year":"2022","unstructured":"Heidenreich, P. A., Bozkurt, B., Aguilar, D., Allen, L. A., Byun, J. J., Colvin, M. M., Deswal, A., Drazner, M. H., Dunlay, S. M., Evers, L. R., & Fang, J. C. (2022). 2022 AHA\/ACC\/HFSA guideline for the management of heart failure: A report of the American college of cardiology\/American heart association joint committee on clinical practice guidelines. Journal of the American College of Cardiology, 79(17), e263\u2013e421. https:\/\/doi.org\/10.1161\/CIR.0000000000001063","journal-title":"Journal of the American College of Cardiology"},{"issue":"3","key":"10133_CR6","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1007\/s12609-017-0249-4","volume":"9","author":"S Nowsheen","year":"2017","unstructured":"Nowsheen, S., Viscuse, P. V., O\u2019Sullivan, C. C., Sandhu, N. P., Haddad, T. C., Blaes, A., Klemp, J., Nhola, L., Herrmann, J., & Ruddy, K. J. (2017). Incidence, diagnosis, and treatment of cardiac toxicity from trastuzumab in patients with breast cancer. Current Breast Cancer Reports, 9(3), 173\u2013182. https:\/\/doi.org\/10.1007\/s12609-017-0249-4","journal-title":"Current Breast Cancer Reports"},{"issue":"22","key":"10133_CR7","doi-asserted-by":"publisher","first-page":"1981","DOI":"10.1161\/CIRCULATIONAHA.114.013777","volume":"131","author":"D Cardinale","year":"2015","unstructured":"Cardinale, D., Colombo, A., Bacchiani, G., Tedeschi, I., Meroni, C. A., Veglia, F., Civelli, M., Lamantia, G., Colombo, N., Curigliano, G., & Fiorentini, C. (2015). Early detection of anthracycline cardiotoxicity and improvement with heart failure therapy. Circulation, 131(22), 1981\u20131988. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.114.013777","journal-title":"Circulation"},{"issue":"1","key":"10133_CR8","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.jaccao.2022.01.099","volume":"4","author":"KW Reding","year":"2022","unstructured":"Reding, K. W., Cheng, R. K., Vasbinder, A., Ray, R. M., Barac, A., Eaton, C. B., Saquib, N., Shadyab, A. H., Simon, M. S., Langford, D., & Branch, M. (2022). Lifestyle and cardiovascular risk factors associated with heart failure subtypes in postmenopausal breast cancer survivors. Cardio Oncology, 4(1), 53\u201365. https:\/\/doi.org\/10.1016\/j.jaccao.2022.01.099","journal-title":"Cardio Oncology"},{"issue":"32","key":"10133_CR9","doi-asserted-by":"publisher","first-page":"3688","DOI":"10.1200\/JCO.22.00111","volume":"40","author":"KW Reding","year":"2022","unstructured":"Reding, K. W., Cheng, R. K., Barac, A., Vasbinder, A., Hovsepyan, G., Stefanick, M., & Simon, M. S. (2022). Toward a better understanding of the differential impact of heart failure phenotypes after breast cancer. Journal of Clinical Oncology, 40(32), 3688\u20133691. https:\/\/doi.org\/10.1200\/JCO.22.00111","journal-title":"Journal of Clinical Oncology"},{"issue":"2","key":"10133_CR10","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1016\/j.cardfail.2024.08.045","volume":"31","author":"MW Bloom","year":"2025","unstructured":"Bloom, M. W., Vo, J. B., Rodgers, J. E., Ferrari, A. M., Nohria, A., Deswal, A., Cheng, R. K., Kittleson, M. M., Upshaw, J. N., Palaskas, N., & Blaes, A. (2025). Cardio-oncology and heart failure: A scientific statement from the heart failure society of America. Journal of Cardiac Failure, 31(2), 415\u2013455. https:\/\/doi.org\/10.1016\/j.cardfail.2024.08.045","journal-title":"Journal of Cardiac Failure"},{"issue":"20","key":"10133_CR11","doi-asserted-by":"publisher","first-page":"2476","DOI":"10.1016\/j.jacc.2017.08.074","volume":"70","author":"KS Shah","year":"2017","unstructured":"Shah, K. S., Xu, H., Matsouaka, R. A., Bhatt, D. L., Heidenreich, P. A., Hernandez, A. F., Devore, A. D., Yancy, C. W., & Fonarow, G. C. (2017). Heart failure with preserved, borderline, and reduced ejection fraction: 5-year outcomes. Journal of the American College of Cardiology, 70(20), 2476\u20132486. https:\/\/doi.org\/10.1016\/j.jacc.2017.08.074","journal-title":"Journal of the American College of Cardiology"},{"issue":"9","key":"10133_CR12","doi-asserted-by":"publisher","first-page":"e139","DOI":"10.1161\/CIR.0000000000000757","volume":"141","author":"SS Virani","year":"2020","unstructured":"Virani, S. S., Alonso, A., Benjamin, E. J., Bittencourt, M. S., Callaway, C. W., Carson, A. P., Chamberlain, A. M., Chang, A. R., Cheng, S., Delling, F. N., & Djousse, L. (2020). Heart disease and stroke statistics\u20142020 update: A report from the American heart association. Circulation, 141(9), e139\u2013e596. https:\/\/doi.org\/10.1161\/CIR.0000000000000757","journal-title":"Circulation"},{"issue":"41","key":"10133_CR13","doi-asserted-by":"publisher","first-page":"4229","DOI":"10.1093\/eurheartj\/ehac244","volume":"43","author":"AR Lyon","year":"2022","unstructured":"Lyon, A. R., L\u00f3pez-Fern\u00e1ndez, T., Couch, L. S., ESC Scientific Document Group. (2022). 2022 ESC guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS). European Heart Journal, 43(41), 4229\u20134361. https:\/\/doi.org\/10.1093\/eurheartj\/ehac244","journal-title":"European Heart Journal"},{"issue":"4","key":"10133_CR14","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1053\/j.seminhematol.2015.07.006","volume":"52","author":"MD Cappellini","year":"2015","unstructured":"Cappellini, M. D., & Motta, I. (2015). Anemia in clinical practice\u2014definition and classification: Does hemoglobin change with aging? Seminars in Hematology, 52(4), 261\u2013269. https:\/\/doi.org\/10.1053\/j.seminhematol.2015.07.006","journal-title":"Seminars in Hematology"},{"issue":"6","key":"10133_CR15","doi-asserted-by":"publisher","first-page":"982","DOI":"10.1053\/j.ajkd.2008.12.034","volume":"53","author":"S Matsuo","year":"2009","unstructured":"Matsuo, S., Imai, E., Horio, M., Yasuda, Y., Tomita, K., Nitta, K., Yamagata, K., Tomino, Y., Yokoyama, H., & Hishida, A. (2009). Revised equations for estimated GFR from serum creatinine in Japan. American Journal of Kidney Diseases, 53(6), 982\u2013992. https:\/\/doi.org\/10.1053\/j.ajkd.2008.12.034","journal-title":"American Journal of Kidney Diseases"},{"issue":"5","key":"10133_CR16","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1253\/circj.CJ-24-0065","volume":"88","author":"K Inoue","year":"2024","unstructured":"Inoue, K., Machino-Ohtsuka, T., Nakazawa, Y., Iida, N., Sasamura, R., Bando, H., Chiba, S., Tasaka, N., Ishizu, T., Murakoshi, N., & Xu, D. (2024). Early detection and prediction of anthracycline-induced cardiotoxicity: A prospective cohort study. Circulation Journal, 88(5), 751\u2013759. https:\/\/doi.org\/10.1253\/circj.CJ-24-0065","journal-title":"Circulation Journal"},{"issue":"9","key":"10133_CR17","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1093\/jjco\/hyx071","volume":"47","author":"K Tajiri","year":"2017","unstructured":"Tajiri, K., Aonuma, K., & Sekine, I. (2017). Cardiovascular toxic effects of targeted cancer therapy. Japanese Journal of Clinical Oncology, 47(9), 779\u2013785. https:\/\/doi.org\/10.1093\/jjco\/hyx071","journal-title":"Japanese Journal of Clinical Oncology"},{"issue":"8","key":"10133_CR18","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1038\/s41569-025-01126-1","volume":"22","author":"I Fabiani","year":"2025","unstructured":"Fabiani, I., Chianca, M., Cipolla, C. M., & Cardinale, D. M. (2025). Anthracycline-induced cardiomyopathy: Risk prediction, prevention and treatment. Nature Reviews Cardiology, 22(8), 551\u2013563. https:\/\/doi.org\/10.1038\/s41569-025-01126-1","journal-title":"Nature Reviews Cardiology"},{"issue":"18","key":"10133_CR19","doi-asserted-by":"publisher","first-page":"3451","DOI":"10.1093\/cvr\/cvac132","volume":"118","author":"S de Wit","year":"2022","unstructured":"de Wit, S., Glen, C., de Boer, R. A., & Lang, N. N. (2022). Mechanisms shared between cancer, heart failure, and targeted anti-cancer therapies. Cardiovascular Research, 118(18), 3451\u20133466. https:\/\/doi.org\/10.1093\/cvr\/cvac132","journal-title":"Cardiovascular Research"},{"issue":"12","key":"10133_CR20","doi-asserted-by":"publisher","first-page":"2214","DOI":"10.1002\/1097-0142(20010615)91:12<2214::AID-CNCR1251>3.0.CO;2-P","volume":"91","author":"JJ Caro","year":"2001","unstructured":"Caro, J. J., Salas, M., Ward, A., & Goss, G. (2001). Anemia as an independent prognostic factor for survival in patients with cancer: A systematic, quantitative review. Cancer, 91(12), 2214\u20132221.","journal-title":"Cancer"}],"container-title":["Cardiovascular Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12012-026-10133-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12012-026-10133-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12012-026-10133-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T19:12:42Z","timestamp":1782846762000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12012-026-10133-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,26]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10133"],"URL":"https:\/\/doi.org\/10.1007\/s12012-026-10133-8","relation":{},"ISSN":["1530-7905","1559-0259"],"issn-type":[{"value":"1530-7905","type":"print"},{"value":"1559-0259","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,26]]},"assertion":[{"value":"30 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}},{"value":"This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of National Cancer Center (January 31, 2023\/No. 2022-384).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"The requirement of informed consent was waived because this study was conducted according to a retrospective chart review protocol.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}}],"article-number":"60"}}