{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T22:55:47Z","timestamp":1773269747823,"version":"3.50.1"},"reference-count":7,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2013,1,13]],"date-time":"2013-01-13T00:00:00Z","timestamp":1358035200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell Biochem Biophys"],"published-print":{"date-parts":[[2013,6]]},"DOI":"10.1007\/s12013-012-9483-6","type":"journal-article","created":{"date-parts":[[2013,1,12]],"date-time":"2013-01-12T06:53:00Z","timestamp":1357973580000},"page":"403-407","source":"Crossref","is-referenced-by-count":16,"title":["Plaque Image Characteristics, Hyperhomocysteinemia, and Gene Polymorphism of Homocysteine Metabolism-Related Enzyme (MTHFR C677T) in Acute Coronary Syndrome"],"prefix":"10.1007","volume":"66","author":[{"given":"Huipu","family":"Xu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changmei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qinghai","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,1,13]]},"reference":[{"key":"9483_CR1","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1161\/01.CIR.0000142865.04816.89","volume":"110","author":"ML Rossi","year":"2004","unstructured":"Rossi, M. L., Marziliano, N., Merlini, P. A., et al. (2004). Different quantitative apoptotic traits in coronary atherosclerosis plaques from patients with stable angina pectoris and acute coronary syndromes. Circulation, 110, 1767\u20131773.","journal-title":"Circulation"},{"key":"9483_CR2","doi-asserted-by":"crossref","first-page":"353","DOI":"10.2165\/00129784-200101050-00005","volume":"1","author":"K Nakai","year":"2001","unstructured":"Nakai, K., Itoh, C., Nakai, K., et al. (2001). Correlation between C677T MTHFR gene polymorphism, plasma homocysteine levels and the incidence of CAD. American Journal of Cardiovascular Drugs, 1, 353\u2013361.","journal-title":"American Journal of Cardiovascular Drugs"},{"key":"9483_CR3","first-page":"189","volume":"5","author":"P Ortolani","year":"2004","unstructured":"Ortolani, P., Marzocchi, A., Marrozzini, C., et al. (2004). Clinical relevance of homocysteine levels in patients receiving coronary stenting for unstable angina. Italian Heart Journal, 5, 189\u2013196.","journal-title":"Italian Heart Journal"},{"key":"9483_CR4","doi-asserted-by":"crossref","first-page":"389","DOI":"10.2143\/AC.58.5.2005302","volume":"58","author":"H Dinckalm","year":"2003","unstructured":"Dinckalm, H., Aksoy, N., Aksoy, M., et al. (2003). Effect of homocysteine lowering therapy on vascular endothelial function and exercise performance in coronary patients with hyperhomocysteinaemia. Acta Cardiologica, 58, 389.","journal-title":"Acta Cardiologica"},{"key":"9483_CR5","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/ng0595-111","volume":"10","author":"P Frosst","year":"1995","unstructured":"Frosst, P., Blam, H. J., Milos, R., et al. (1995). A candidate genetic risk factor for vascular disease: a common mutation methylenetetrahydrofolate. Nature Genetics, 10, 111\u2013113.","journal-title":"Nature Genetics"},{"key":"9483_CR6","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1097\/00019501-200002000-00009","volume":"11","author":"K Nakai","year":"2000","unstructured":"Nakai, K., Fusazaki, T., Suzuki, T., et al. (2000). Genetic polymorphism of 5,10-methylenetetrahydrofolate increases risk of myocardial infarction and is correlated to elevated levels of homocysteine in the Japanese general population. Coronary Artery Disease, 11, 47\u201351.","journal-title":"Coronary Artery Disease"},{"issue":"5","key":"9483_CR7","doi-asserted-by":"crossref","first-page":"353","DOI":"10.2165\/00129784-200101050-00005","volume":"1","author":"K Nakai","year":"2001","unstructured":"Nakai, K., Itoh, C., Nakai, K., et al. (2001). Correlation between C677T MTHFR gene polymorphism, plasma homocysteine levels and the incidence of CAD[J]. American Journal of Cardiovascular Drugs, 1(5), 353\u2013361.","journal-title":"American Journal of Cardiovascular Drugs"}],"container-title":["Cell Biochemistry and Biophysics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12013-012-9483-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12013-012-9483-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12013-012-9483-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,8]],"date-time":"2019-07-08T06:41:47Z","timestamp":1562568107000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12013-012-9483-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,13]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["9483"],"URL":"https:\/\/doi.org\/10.1007\/s12013-012-9483-6","relation":{},"ISSN":["1085-9195","1559-0283"],"issn-type":[{"value":"1085-9195","type":"print"},{"value":"1559-0283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,13]]}}}