{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T18:44:21Z","timestamp":1793645061118,"version":"4.5.1"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2013,5,31]],"date-time":"2013-05-31T00:00:00Z","timestamp":1369958400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell Biochem Biophys"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1007\/s12013-013-9655-z","type":"journal-article","created":{"date-parts":[[2013,5,30]],"date-time":"2013-05-30T06:56:29Z","timestamp":1369896989000},"page":"1521-1527","source":"Crossref","is-referenced-by-count":1,"title":["Clinical Application of RT-Nested PCR Integrated with RFLP in Hantavirus Detection and Genotyping: A Prospective Study in Shandong Province, PR China"],"prefix":"10.1007","volume":"67","author":[{"given":"Yun-Xi","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhong-Tang","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wu-Chun","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Qun","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Jiang","family":"Suo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Bin","family":"Xing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Mei","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo-Wei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,5,31]]},"reference":[{"key":"9655_CR1","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/0042-6822(83)90514-7","volume":"131","author":"CS Schmaljohn","year":"1983","unstructured":"Schmaljohn, C. S., & Dalrymple, J. M. (1983). Analysis of Hantaan virus RNA: Evidence for a new genus of Bunyaviridae. Virology, 131, 482\u2013491.","journal-title":"Virology"},{"key":"9655_CR2","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1126\/science.8235615","volume":"262","author":"ST Nichol","year":"1993","unstructured":"Nichol, S. T., Spiropoulou, C. F., Morzunov, S., et al. (1993). Genetic identification of a Hantavirus associated with an outbreak of acute respiratory illness. Science, 262, 914\u2013917.","journal-title":"Science"},{"key":"9655_CR3","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.1099\/0022-1317-77-11-2677","volume":"77","author":"A Plyusnin","year":"1996","unstructured":"Plyusnin, A., Vapalahti, O., & Vaheri, A. (1996). Hantavirus: Genome structure, expression and evolution. Journal of General Virology, 77, 2677\u20132687.","journal-title":"Journal of General Virology"},{"key":"9655_CR4","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0166-3542(02)00205-X","volume":"57","author":"JP Clement","year":"2003","unstructured":"Clement, J. P. (2003). Hantavirus. Antiviral Research, 57, 121\u2013127.","journal-title":"Antiviral Research"},{"key":"9655_CR5","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/S1473-3099(03)00774-6","volume":"3","author":"O Vapalahti","year":"2003","unstructured":"Vapalahti, O., Mustonen, J., Lundkvist, A., et al. (2003). Hantavirus infections in Europe. Lancet Infect Disease, 3, 653\u2013661.","journal-title":"Lancet Infect Disease"},{"key":"9655_CR6","doi-asserted-by":"crossref","first-page":"3669","DOI":"10.1681\/ASN.2005050561","volume":"16","author":"W Muranyi","year":"2005","unstructured":"Muranyi, W., Bahr, U., Zeier, M., et al. (2005). Hantavirus Infection. Journal of the American Society of Nephrology, 16, 3669\u20133679.","journal-title":"Journal of the American Society of Nephrology"},{"key":"9655_CR7","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1093\/oxfordjournals.molbev.a026254","volume":"17","author":"AL Hughes","year":"2000","unstructured":"Hughes, A. L., & Friedman, R. (2000). Evolutionary diversification of protein-coding genes of Hantaviruses. Molecular Biology and Evolution, 17, 1558\u20131568.","journal-title":"Molecular Biology and Evolution"},{"key":"9655_CR8","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/s11262-004-5625-2","volume":"30","author":"M Zeier","year":"2005","unstructured":"Zeier, M., Handermann, M., Bahr, U., et al. (2005). New ecological aspects of Hantavirus infection: A Change of a paradigm and a challenge of prevention\u2013a review. Virus Genes, 30, 157\u2013180.","journal-title":"Virus Genes"},{"key":"9655_CR9","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1016\/S1286-4579(99)00238-5","volume":"1","author":"CA Hart","year":"1999","unstructured":"Hart, C. A., & Bennettb, M. (1999). Hantavirus infections: Epidemiology and pathogenesis. Microbes and Infection, 1, 1229\u20131237.","journal-title":"Microbes and Infection"},{"key":"9655_CR10","first-page":"472","volume":"112","author":"G Song","year":"1999","unstructured":"Song, G. (1999). Epidemiological progresses of hemorrhagic fever with renal syndrome in China. Chinese Medical Journal, 112, 472\u2013477.","journal-title":"Chinese Medical Journal"},{"key":"9655_CR11","first-page":"197","volume":"20","author":"X Bai","year":"2002","unstructured":"Bai, X., & Huang, C. (2002). Strengthen further the study on hemorrhagic fever with renal syndrome. Chinese Journal of Infectious Diseases, 20, 197\u2013198.","journal-title":"Chinese Journal of Infectious Diseases"},{"key":"9655_CR12","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1128\/JCM.29.9.1924-1927.1991","volume":"29","author":"YW Tang","year":"1991","unstructured":"Tang, Y. W., Li, Y. L., Ye, K. L., et al. (1991). Distribution of Hantavirus serotypes Hantaan and Seoul causing hemorrhagic fever with renal syndrome and identification by hemagglutination inhibition assay. Journal of Clinical Microbiology, 29, 1924\u20131927.","journal-title":"Journal of Clinical Microbiology"},{"key":"9655_CR13","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0168-1702(94)90005-1","volume":"31","author":"M Liang","year":"1994","unstructured":"Liang, M., Li, D., Xiao, S. Y., et al. (1994). Antigenic and molecular characterization of Hantavirus isolates from China. Virus Research, 31, 219\u2013233.","journal-title":"Virus Research"},{"key":"9655_CR14","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0168-1702(98)00065-3","volume":"56","author":"XH Shi","year":"1998","unstructured":"Shi, X. H., Liang, M. F., Hang, C. S., et al. (1998). Nucleotide sequence and phylogenetic analysis of the medium (M) genomic RNA segments of three Hantaviruses isolated in China. Virus Research, 56, 69\u201376.","journal-title":"Virus Research"},{"key":"9655_CR15","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1002\/jmv.1890430309","volume":"43","author":"EC Kim","year":"1994","unstructured":"Kim, E. C., Kim, I. S., Choi, Y., et al. (1994). Rapid differentiation between Hantaan and Seoul viruses by PCR and restriction enzyme analysis. Journal of Medical Virology, 43, 245\u2013248.","journal-title":"Journal of Medical Virology"},{"key":"9655_CR16","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1099\/0022-1317-74-8-1657","volume":"74","author":"SY Xiao","year":"1993","unstructured":"Xiao, S. Y., Liang, M., & Schmaljohn, C. S. (1993). Molecular and antigenic characterization of HV114, a Hantavirus isolated from a patient with haemorrhagic fever with renal syndrome in China. Journal of General Virology, 74, 1657\u20131659.","journal-title":"Journal of General Virology"},{"key":"9655_CR17","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/0042-6822(86)90223-0","volume":"155","author":"CS Schmaljohn","year":"1986","unstructured":"Schmaljohn, C. S., Jennings, G. B., Hay, J., et al. (1986). Coding strategy of the S genome segment of Hantavirus. Virology, 155, 633\u2013643.","journal-title":"Virology"},{"key":"9655_CR18","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/0042-6822(90)90236-K","volume":"176","author":"J Arikawa","year":"1990","unstructured":"Arikawa, J., Lapenotiere, H. F., Iacono-Connors, L., et al. (1990). Coding properties of the S and the M genome segments of Sapporo rat virus: Comparison to other causative agents of hemorrhagic fever with renal syndrome. Virology, 176, 114\u2013125.","journal-title":"Virology"},{"key":"9655_CR19","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0003-2697(87)90021-2","volume":"162","author":"P Chomczynski","year":"1987","unstructured":"Chomczynski, P., & Sacchi, N. (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate\u2014phenol-chloroform extraction. Analytical Biochemistry, 162, 156\u2013159.","journal-title":"Analytical Biochemistry"},{"key":"9655_CR20","first-page":"79","volume":"53","author":"C Ahn","year":"2000","unstructured":"Ahn, C., Cho, J. T., Lee, J. G., et al. (2000). Detection of Hantaan and Seoul viruses by reverse transcriptase-polymerase chain reaction (RT-PCR) and restriction fragment length polymorphism (RFLP) in renal syndrome patients with hemorrhagic fever. Clinical Nephrology, 53, 79\u201389.","journal-title":"Clinical Nephrology"},{"key":"9655_CR21","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1006\/viro.2000.0630","volume":"278","author":"H Wang","year":"2000","unstructured":"Wang, H., Yoshimatsu, K., Ebihara, H., et al. (2000). Genetic diversity of Hantaviruses isolated in China and characterization of novel Hantaviruses isolated from Niviventer confucianus and Rattus rattus. Virology, 278, 332\u2013345.","journal-title":"Virology"},{"key":"9655_CR22","first-page":"211","volume":"18","author":"SW Wang","year":"2002","unstructured":"Wang, S. W., Hang, C. S., Wang, H., et al. (2002). Genotype and clade distribution of Hantavirus in China. China Journal of Virology, 18, 211\u2013216.","journal-title":"China Journal of Virology"},{"key":"9655_CR23","first-page":"341","volume":"17","author":"D Kang","year":"2001","unstructured":"Kang, D., Ruan, Y., Fu, J., et al. (2001). Epidemiological changes of hemorrhage fever with renal syndrome in Shandong Province, 1990\u20131998. Chinese Journal of Epidemiology, 17, 341\u2013342.","journal-title":"China Public Health"},{"key":"9655_CR24","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1006\/viro.1995.1020","volume":"206","author":"D Li","year":"1995","unstructured":"Li, D., Schmaljohn, A. L., Anderson, K., et al. (1995). Complete nucleotides sequences of the M and S segment of two Hantavirus isolates from California;evidence for reassortment in nature among virus related to Hantavirus pulmonary syndrome. Virology, 206, 973\u2013983.","journal-title":"Virology"}],"container-title":["Cell Biochemistry and Biophysics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12013-013-9655-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12013-013-9655-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12013-013-9655-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,27]],"date-time":"2020-07-27T08:46:39Z","timestamp":1595839599000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12013-013-9655-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,31]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["9655"],"URL":"https:\/\/doi.org\/10.1007\/s12013-013-9655-z","relation":{},"ISSN":["1085-9195","1559-0283"],"issn-type":[{"value":"1085-9195","type":"print"},{"value":"1559-0283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5,31]]}}}