{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T14:17:23Z","timestamp":1770992243523,"version":"3.50.1"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2015,5,27]],"date-time":"2015-05-27T00:00:00Z","timestamp":1432684800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2015,5,27]],"date-time":"2015-05-27T00:00:00Z","timestamp":1432684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cell Biochem Biophys"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1007\/s12013-015-0642-4","type":"journal-article","created":{"date-parts":[[2015,5,26]],"date-time":"2015-05-26T14:13:57Z","timestamp":1432649637000},"page":"707-716","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Cardioprotective Effect of Anisodamine Against Myocardial Ischemia Injury and its Influence on Cardiomyocytes Apoptosis"],"prefix":"10.1007","volume":"73","author":[{"given":"Kun","family":"Xing","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianghua","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingling","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanbo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinshun","family":"Gu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guozhen","family":"Hao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing","family":"Miao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaolin","family":"Ge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhong","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Geng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiru","family":"Bai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liye","family":"Wei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xile","family":"Bi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,5,27]]},"reference":[{"key":"642_CR1","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1093\/eurheartj\/ehi810","volume":"27","author":"E Boersma","year":"2006","unstructured":"Boersma, E. (2006). Does time matter? A pooled analysis of randomized clinical trials comparing primary percutaneous coronary intervention and in-hospital fibrinolysis in acute myocardial infarction patients. European Heart Journal, \n                           27, 779\u2013788.","journal-title":"European Heart Journal"},{"key":"642_CR2","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/j.carpath.2005.03.006","volume":"14","author":"LM Buja","year":"2005","unstructured":"Buja, L. M. (2005). Myocardial ischemia and reperfusion injury. Cardiovascular Pathology, \n                           14, 170\u2013175.","journal-title":"Cardiovascular Pathology"},{"issue":"6","key":"642_CR3","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1177\/1708538113478756","volume":"21","author":"L Chen","year":"2013","unstructured":"Chen, L., Ling, Y. S., Lin, C. H., & Guan, T. J. (2013). Combined use of heparin and anisodamine reduces the risk of early thrombosis in native arteriovenous fistula. Vascular, \n                           21(6), 369\u2013374.","journal-title":"Vascular"},{"key":"642_CR4","first-page":"H1743","volume":"260","author":"K Esumi","year":"1991","unstructured":"Esumi, K., Nishida, M., Shaw, D., Smith, T. W., & Marsh, J. D. (1991). NADH measurements in adult rat myocytes during simulated ischemia. American Journal of Physiology, \n                           260, H1743\u2013H1752.","journal-title":"American Journal of Physiology"},{"key":"642_CR5","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/j.ejcts.2010.05.036","volume":"39","author":"M Foadoddini","year":"2011","unstructured":"Foadoddini, M., Esmailidehaj, M., Mehrani, H., Sadraei, S. H., Golmanesh, L., Wahhabaghai, H., et al. (2011). Pretreatment with hyperoxia reduces in vivo infarct size and cell death by apoptosis with an early and delayed phase of protection. European Journal of Cardio-Thoracic Surgery, \n                           39, 233\u2013240.","journal-title":"European Journal of Cardio-Thoracic Surgery"},{"key":"642_CR6","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1097\/00029330-200707020-00004","volume":"120","author":"XH Fu","year":"2007","unstructured":"Fu, X. H., Fan, W. Z., Gu, X. S., Wei, Y. Y., Jiang, Y. F., Wu, W. L., et al. (2007). Effect of intracoronary administration of anisodamine on slow reflow phenomenon following primary percutaneous coronary intervention in patients with acute myocardial infarction. Chinese Medical Journal, \n                           120, 1226\u20131231.","journal-title":"Chinese Medical Journal"},{"key":"642_CR7","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1097\/00029330-200707020-00004","volume":"120","author":"XH Fu","year":"2007","unstructured":"Fu, X. H., Fan, W. Z., Gu, X. S., Wei, Y. Y., Jiang, Y. F., Wu, W. L., et al. (2007). Effect of intracoronary administration of anisodamine on slow reflow phenomenon following primary percutaneous coronary intervention in patients with acute myocardial infarction. Chinese Medical Journal, \n                           120, 1226\u20131231.","journal-title":"Chinese Medical Journal"},{"key":"642_CR8","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1007\/s00392-010-0273-0","volume":"100","author":"G Klug","year":"2011","unstructured":"Klug, G., Mayr, A., Mair, J., Schocke, M., Nocker, M., Trieb, T., et al. (2011). Role of biomarkers in assessment of early infarct size after successful p-PCI for STEMI. Clinical Research in Cardiology, \n                           100, 501\u2013510.","journal-title":"Clinical Research in Cardiology"},{"key":"642_CR9","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1016\/j.bbrc.2010.02.017","volume":"393","author":"M Kondo-Nakamura","year":"2010","unstructured":"Kondo-Nakamura, M., Shintani-Ishida, K., Uemura, K., & Yoshida, K. (2010). Brief exposure to carbon monoxide preconditions cardiomyogenic cells against apoptosis in ischemia-reperfusion. Biochemical and Biophysical Research Communications, \n                           393, 449\u2013454.","journal-title":"Biochemical and Biophysical Research Communications"},{"key":"642_CR10","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.bbrc.2010.09.037","volume":"401","author":"Y Liu","year":"2010","unstructured":"Liu, Y., Huo, Z., Yan, B., Lin, X., Zhou, Z. N., Liang, X., et al. (2010). Prolyl hydroxylase 3 interacts with Bcl-2 to regulate doxorubicin-induced apoptosis in H9c2 cells. Biochemical and Biophysical Research Communications, \n                           401, 231\u2013237.","journal-title":"Biochemical and Biophysical Research Communications"},{"key":"642_CR11","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1097\/00000542-200403000-00011","volume":"100","author":"LM Ludwig","year":"2004","unstructured":"Ludwig, L. M., Weihrauch, D., Kersten, J. R., Pagel, P. S., & Warltier, D. C. (2004). Protein kinase C translocation and Src protein tyrosine kinase activation mediate isoflurane-induced preconditioning in vivo: potential downstream targets of mitochondrial adenosine triphosphate-sensitive potassium channels and reactive oxygen species. Anesthesiology, \n                           100, 532\u2013539.","journal-title":"Anesthesiology"},{"key":"642_CR12","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1016\/0962-8924(94)90053-1","volume":"4","author":"G Nunez","year":"1994","unstructured":"Nunez, G., & Clarke, M. F. (1994). The Bcl-2 family of proteins: Regulators of cell death and survival. Trends in Cell Biology, \n                           4, 399\u2013403.","journal-title":"Trends in Cell Biology"},{"key":"642_CR13","doi-asserted-by":"publisher","first-page":"2005","DOI":"10.1006\/jmcc.1996.0193","volume":"28","author":"G Olivetti","year":"1996","unstructured":"Olivetti, G., Quaini, F., Sala, R., Lagrasta, C., Corradi, D., Bonacina, E., et al. (1996). Acute myocardial infarction in humans is associated with activation of programmed myocyte cell death in the surviving portion of the heart. Journal of Molecular and Cellular Cardiology, \n                           28, 2005\u20132016.","journal-title":"Journal of Molecular and Cellular Cardiology"},{"key":"642_CR14","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1002\/jat.1154","volume":"27","author":"JM Poupko","year":"2007","unstructured":"Poupko, J. M., Baskin, S. I., & Moore, E. (2007). The pharmacological properties of anisodamine. Journal of Applied Toxicology, \n                           27, 116\u2013121.","journal-title":"Journal of Applied Toxicology"},{"key":"642_CR15","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1016\/j.bbrc.2014.12.022","volume":"456","author":"T Silambarasan","year":"2015","unstructured":"Silambarasan, T., Manivannan, J., Priya, M. K., Suganya, N., Chatterjee, S., & Raja, B. (2015). Sinapic acid protects heart against ischemia\/reperfusion injury and H9c2 cardiomyoblast cells against oxidative stress. Biochemical and Biophysical Research Communications, \n                           456, 853\u2013859.","journal-title":"Biochemical and Biophysical Research Communications"},{"key":"642_CR16","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.cell.2011.03.025","volume":"145","author":"ME Soriano","year":"2011","unstructured":"Soriano, M. E., & Scorrano, L. (2011). Traveling Bax and forth from mitochondria to control apoptosis. Cell, \n                           145, 15\u201317.","journal-title":"Cell"},{"key":"642_CR17","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1186\/1468-6708-6-12","volume":"6","author":"AT Turer","year":"2005","unstructured":"Turer, A. T., Mahaffey, K. W., Gallup, D., Weaver, W. D., Christenson, R. H., Every, N. R., & Ohman, E. M. (2005). Enzyme estimates of infarct size correlate with functional and clinical outcomes in the setting of ST-segment elevation myocardial infarction. Current Controlled Trials in Cardiovascular Medicine, \n                           6, 12.","journal-title":"Current Controlled Trials in Cardiovascular Medicine"},{"key":"642_CR18","doi-asserted-by":"publisher","first-page":"1458","DOI":"10.1001\/jama.247.10.1458","volume":"247","author":"RJ Xiu","year":"1982","unstructured":"Xiu, R. J., Hammerschmidt, D. E., Coppo, P. A., & Jacob, H. S. (1982). Anisodamine inhibits thromboxane synthesis, granulocyte aggregation, and platelet aggregation. A possible mechanism for its efficacy in bacteremic shock. JAMA, \n                           247, 1458\u20131460.","journal-title":"JAMA"},{"key":"642_CR19","doi-asserted-by":"publisher","first-page":"1458","DOI":"10.1001\/jama.247.10.1458","volume":"247","author":"RJ Xiu","year":"1982","unstructured":"Xiu, R. J., Hammerschmidt, D. E., Coppo, P. A., & Jacob, H. S. (1982). Anisodamine inhibits thromboxane synthesis, granulocyte aggregation, and platelet aggregation: A possible mechanism for its efficacy in bacteremic shock. JAMA, \n                           247, 1458\u20131460.","journal-title":"JAMA"},{"key":"642_CR20","first-page":"173","volume":"12","author":"P Yang","year":"1991","unstructured":"Yang, P., Zhang, B. H., & Hong, N. (1991). Anti-arrhythmia and vegetative nervous system effects of Anisodamine. Acta Pharmacologica Sinica, \n                           12, 173\u2013176.","journal-title":"Acta Pharmacologica Sinica"},{"key":"642_CR21","first-page":"300","volume":"125","author":"ZX Zhang","year":"2012","unstructured":"Zhang, Z. X., Wang, P., Zhang, Q. S., Pan, X., Zhao, Q. X., & Wang, X. K. (2012). Effects of anisodamine on the expressions of vascular endothelial growth factor and intercellular adhesion molecule 1 in experimental infusion phlebitis. Chinese Medical Journal, \n                           125, 300\u2013305.","journal-title":"Chinese Medical Journal"},{"key":"642_CR22","first-page":"300","volume":"125","author":"ZX Zhang","year":"2012","unstructured":"Zhang, Z. X., Wang, P., Zhang, Q. S., Pan, X., Zhao, Q. X., & Wang, X. K. (2012). Effects of anisodamine on the expressions of vascular endothelial growth factor and intercellular adhesion molecule 1 in experimental infusion phlebitis. Chinese Medical Journal, \n                           125, 300\u2013305.","journal-title":"Chinese Medical Journal"},{"key":"642_CR23","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1016\/S0008-6363(99)00354-5","volume":"45","author":"ZQ Zhao","year":"2000","unstructured":"Zhao, Z. Q., Nakamura, M., Wang, N. P., Wilcox, J. N., Shearer, S., Ronson, R. S., et al. (2000). Reperfusion induces myocardial apoptotic cell death. Cardiovascular Research, \n                           45, 651\u2013660.","journal-title":"Cardiovascular Research"}],"container-title":["Cell Biochemistry and Biophysics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12013-015-0642-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12013-015-0642-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12013-015-0642-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12013-015-0642-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,9]],"date-time":"2020-10-09T18:13:46Z","timestamp":1602267226000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12013-015-0642-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,27]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["642"],"URL":"https:\/\/doi.org\/10.1007\/s12013-015-0642-4","relation":{},"ISSN":["1085-9195","1559-0283"],"issn-type":[{"value":"1085-9195","type":"print"},{"value":"1559-0283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5,27]]},"assertion":[{"value":"27 May 2015","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}