{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T06:17:24Z","timestamp":1771481844039,"version":"3.50.1"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,11,12]],"date-time":"2021-11-12T00:00:00Z","timestamp":1636675200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2021,11,12]],"date-time":"2021-11-12T00:00:00Z","timestamp":1636675200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cell Biochem Biophys"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1007\/s12013-021-01042-4","type":"journal-article","created":{"date-parts":[[2021,11,12]],"date-time":"2021-11-12T14:02:36Z","timestamp":1636725756000},"page":"217-228","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Transcriptomic Response of Primary Human Bronchial Cells to Repeated Exposures of Cigarette and ENDS Preparations"],"prefix":"10.1007","volume":"80","author":[{"given":"Rachael E.","family":"Rayner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jack","family":"Wellmerling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrudu","family":"Makena","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. L.","family":"Prasad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Estelle","family":"Cormet-Boyaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,11,12]]},"reference":[{"issue":"2","key":"1042_CR1","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1378\/chest.13-0274","volume":"144","author":"MT Dransfield","year":"2013","unstructured":"Dransfield, M. T., Wilhelm, A. M., Flanagan, B., Courville, C., Tidwell, S. L., Raju, S. V., Gaggar, A., Steele, C., Tang, L. P., & Lui, B., et al. (2013). Acquired cystic fibrosis transmembrane conductance regulator dysfunction in the lower airways in COPD. Chest, 144(2), 498\u2013506.","journal-title":"Chest"},{"issue":"1","key":"1042_CR2","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1186\/1471-2466-11-36","volume":"11","author":"BA Forey","year":"2011","unstructured":"Forey, B. A., Thornton, A. J., & Lee, P. N. (2011). Systematic review with meta-analysis of the epidemiological evidence relating smoking to COPD, chronic bronchitis and emphysema. BMC Pulm Med, 11(1), 36.","journal-title":"BMC Pulm Med"},{"issue":"4","key":"1042_CR3","first-page":"327","volume":"4","author":"F Islami","year":"2015","unstructured":"Islami, F., Torre, L. A., & Jemal, A. (2015). Global trends of lung cancer mortality and smoking prevalence. Transl Lung Cancer Res, 4(4), 327\u2013338.","journal-title":"Transl Lung Cancer Res"},{"issue":"1","key":"1042_CR4","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.chest.2016.03.060","volume":"150","author":"L Jayes","year":"2016","unstructured":"Jayes, L., Haslam, P. L., Gratziou, C. G., Powell, P., Britton, J., Vardavas, C., Jimenez-Ruiz, C., & Leonardi-Bee, J. (2016). SmokeHaz: systematic reviews and meta-analysis of the effects of smoking on respiratory health. Chest, 150(1), 164\u2013179.","journal-title":"Chest"},{"issue":"4","key":"1042_CR5","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1002\/ppul.23037","volume":"50","author":"M Silvestri","year":"2015","unstructured":"Silvestri, M., Franchi, S., Pistorio, A., Petechia, L., & Rusconi, F. (2015). Smoke exposure, wheezing, and asthma development: A systematic review and meta-analysis in unselected birth cohorts. Ped Pulm, 50(4), 353\u2013362.","journal-title":"Ped Pulm"},{"key":"1042_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/978-3-319-24223-1_1","volume":"893","author":"LA Torre","year":"2016","unstructured":"Torre, L. A., Siegel, R. L., & Jemal, A. (2016). Lung cancer statistics. Adv Exp Med Biol, 893, 1\u201319.","journal-title":"Adv Exp Med Biol"},{"issue":"8","key":"1042_CR7","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1152\/ajplung.00039.2013","volume":"305","author":"A Rab","year":"2013","unstructured":"Rab, A., Rowe, S. M., Raju, S. V., Bebock, Z., Matalon, S., & Collawn, J. F. (2013). Cigarette smoke and CFTR: implications in the pathogenesis of COPD. AJP - Lung Cell Mol Physiol, 305(8), 530\u2013541.","journal-title":"AJP - Lung Cell Mol Physiol"},{"issue":"12","key":"1042_CR8","doi-asserted-by":"publisher","first-page":"1398","DOI":"10.1152\/ajplung.00272.2015","volume":"309","author":"TR Rowell","year":"2015","unstructured":"Rowell, T. R., & Tarran, R. (2015). Will chronic e-cigarette use cause lung disease? AJP-Lung Cell Mol Physiol, 309(12), 1398\u20131409.","journal-title":"AJP-Lung Cell Mol Physiol"},{"issue":"27","key":"1042_CR9","doi-asserted-by":"publisher","first-page":"10143","DOI":"10.1073\/pnas.0401422101","volume":"101","author":"A Spira","year":"2004","unstructured":"Spira, A., Beane, J., Shah, V., Liu, G., Schembri, F., Yang, X., Palma, J., & Brody, J. S. (2004). Effects of cigarette smoke on the human airway epithelial cell transcriptome. PNAS, 101(27), 10143\u201310148.","journal-title":"PNAS"},{"issue":"3","key":"1042_CR10","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/j.tiv.2016.12.015","volume":"45","author":"S Antherieu","year":"2017","unstructured":"Antherieu, S., Garat, A., Beauval, N., Soyez, M., Allorge, D., Garcon, G., & Lo-Guidice, J. (2017). Comparison of cellular and transcriptomic effects between electronic cigarette vapor and cigarette smoke in human bronchial epithelial cells. Toxicol In Vitro, 45(3), 417\u2013425.","journal-title":"Toxicol In Vitro"},{"key":"1042_CR11","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1016\/j.ypmed.2014.10.009","volume":"69","author":"C Pisinger","year":"2014","unstructured":"Pisinger, C., & Dossing, M. (2014). A systematic review of health effects of electronic cigarettes. Preventive Med, 69, 248\u2013260.","journal-title":"Preventive Med"},{"issue":"19","key":"1042_CR12","doi-asserted-by":"publisher","first-page":"1972","DOI":"10.1161\/CIRCULATIONAHA.114.007667","volume":"129","author":"R Grana","year":"2014","unstructured":"Grana, R., Benowitz, N., & Glantz, S. A. (2014). E-cigarettes: a scientific review. Circulation, 129(19), 1972\u20131986.","journal-title":"Circulation"},{"issue":"1","key":"1042_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-2458-10-231","volume":"10","author":"J-F Etter","year":"2010","unstructured":"Etter, J.-F.(2010). Electronic cigarettes: a survey of users. BMC Public Health, 10(1), 1\u20137.","journal-title":"BMC Public Health"},{"issue":"4","key":"1042_CR14","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1111\/add.13240","volume":"111","author":"JF Etter","year":"2016","unstructured":"Etter, J. F. (2016). Characteristics of users and usage of different types of electronic cigarettes: findings from an online survey. Addiction, 111(4), 724\u2013733.","journal-title":"Addiction"},{"issue":"11","key":"1042_CR15","doi-asserted-by":"publisher","first-page":"2017","DOI":"10.1111\/j.1360-0443.2011.03505.x","volume":"106","author":"JF Etter","year":"2011","unstructured":"Etter, J. F., & Bullen, C. (2011). Electronic cigarette: users profile, utilization, satisfaction and perceived efficacy. Addiction, 106(11), 2017\u20132028.","journal-title":"Addiction"},{"key":"1042_CR16","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.addbeh.2015.09.006","volume":"52","author":"B Pi\u00f1eiro","year":"2016","unstructured":"Pi\u00f1eiro, B., Correa, J. B., Simmons, V. N., Harrell, P. T., Menzie, N. S., Unrod, M., Meltzer, L. R., & Brandon, T. H. (2016). Gender differences in use and expectancies of e-cigarettes: online survey results. Addictive Behaviors, 52, 91\u201397.","journal-title":"Addictive Behaviors"},{"issue":"8","key":"1042_CR17","doi-asserted-by":"publisher","first-page":"940","DOI":"10.1093\/ntr\/ntx194","volume":"20","author":"B Rodu","year":"2018","unstructured":"Rodu, B., & Plurphanswat, N. (2018). E-cigarette use among US adults: Population Assessment of Tobacco and Health (PATH) study. Nicotine and Tobacco Research, 20(8), 940\u2013948.","journal-title":"Nicotine and Tobacco Research"},{"key":"1042_CR18","unstructured":"Amos A., Arnott D., Aveyard P., Bauld L., Bogdanovica I., Britton J., Chenoweth M., Collin J., Dockrell M., Hajek P.: Nicotine without smoke: Tobacco harm reduction. In: 2016: Royal College of Physicians; 2016."},{"key":"1042_CR19","doi-asserted-by":"crossref","unstructured":"Phillips, G., Czekala, L., Behrsing, H. P., Amin, K., Budde, J., Stevenson, M., Wieczorek, R., Walele, T., & Simms, L. (2021). Acute electronic vapour product whole aerosol exposure of 3D human bronchial tissue results in minimal cellular and transcriptomic responses when compared to cigarette smoke. Toxicology Research and Application, 5, 2397847320988496.","DOI":"10.1177\/2397847320988496"},{"key":"1042_CR20","doi-asserted-by":"publisher","first-page":"112472.","DOI":"10.1016\/j.ecoenv.2021.112472","volume":"222","author":"L Wang","year":"2021","unstructured":"Wang, L., Wang, Y., Chen, J., Yang, X.-M., Jiang, X.-T., Liu, P., & Li, M. (2021). Comparison of biological and transcriptomic effects of conventional cigarette and electronic cigarette smoke exposure at toxicological dose in BEAS-2B cells. Ecotoxicology and Environmental Safety, 222, 112472.","journal-title":"Ecotoxicology and Environmental Safety"},{"issue":"1","key":"1042_CR21","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1089\/aivt.2016.0024","volume":"3","author":"A Banerjee","year":"2017","unstructured":"Banerjee, A., Haswell, L. E., Baxter, A., Parmar, A., Azzopardi, D., Corke, S., Thorne, D., Adamson, J., Mushonganono, J., & Gaca, M. D., et al. (2017). Differential gene expression using RNA sequencing profiling in a reconstituted airway epithelium exposed to conventional cigarette smoke or electronic cigarette aerosols. App In Vitro Toxicol, 3(1), 84\u201398.","journal-title":"App In Vitro Toxicol"},{"issue":"1","key":"1042_CR22","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-017-00852-y","volume":"7","author":"LE Haswell","year":"2017","unstructured":"Haswell, L. E., Baxter, A., Banerjee, A., Verrastro, I., Mushonganono, J., Adamson, J., Thorne, D., Ga\u00e7a, M., & Minet, E. (2017). Reduced biological effect of e-cigarette aerosol compared to cigarette smoke evaluated in vitro using normalized nicotine dose and RNA-seq-based toxicogenomics. Sci Rep, 7(1), 1\u201316.","journal-title":"Sci Rep"},{"issue":"2","key":"1042_CR23","doi-asserted-by":"publisher","first-page":"L276","DOI":"10.1152\/ajplung.00452.2020","volume":"320","author":"RE Rayner","year":"2021","unstructured":"Rayner, R. E., Makena, P., Prasad, G. L. & Cormet-Boyaka, E. (2021). Cigarette smoke preparations, not electronic nicotine delivery system preparations, induce features of lung disease in a 3D lung repeat-dose model. Am J Physiol Lung Cell Mol Physiol, 320(2), L276\u2013L287.","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"4","key":"1042_CR24","doi-asserted-by":"publisher","DOI":"10.1038\/srep23984","volume":"6","author":"Y Shen","year":"2016","unstructured":"Shen, Y., Wolkowicz, M. J., Kotova, T., Fan, L., & Timko, M. P. (2016). Transcriptome sequencing reveals e-cigarette vapor and mainstream-smoke from tobacco cigarettes activate different gene expression profiles in human bronchial epithelial cells. Sci Rep, 6(4), 23984.","journal-title":"Sci Rep"},{"issue":"1","key":"1042_CR25","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1093\/toxsci\/kfw198","volume":"155","author":"E Moses","year":"2017","unstructured":"Moses, E., Wang, T., Corbett, S., Jackson, G. R., Drizik, E., Perdomo, C., Perdomo, C., Kleerup, E., Brooks, D., & O\u2019Connor, G., et al. (2017). Molecular impact of electronic cigarette aerosol exposure in human bronchial epithelium. Toxicol Sci, 155(1), 248\u2013257.","journal-title":"Toxicol Sci"},{"issue":"2","key":"1042_CR26","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1152\/ajplung.00096.2019","volume":"317","author":"RE Rayner","year":"2019","unstructured":"Rayner, R. E., Makena, P., Prasad, G. L., & Cormet-Boyaka, E. (2019). Cigarette and ENDS preparations differentially regulate ion channels and mucociliary clearance in primary normal human bronchial 3D cultures. AJP - Lung Mol Cell Phys, 317(2), 295\u2013302.","journal-title":"AJP - Lung Mol Cell Phys"},{"issue":"3","key":"1042_CR27","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1016\/j.yrtph.2012.09.004","volume":"64","author":"S Arimilli","year":"2012","unstructured":"Arimilli, S., Damratoski, B. E., Bombick, B., Borgerding, M. F., & Prasad, G. L. (2012). Evaluation of cytotoxicity of different tobacco product preparations. Reg Toxicol Pharmacol, 64(3), 350\u2013360.","journal-title":"Reg Toxicol Pharmacol"},{"issue":"2","key":"1042_CR28","doi-asserted-by":"publisher","first-page":"L295","DOI":"10.1152\/ajplung.00096.2019","volume":"317","author":"RE Rayner","year":"2019","unstructured":"Rayner, R. E., Makena, P., Prasad, G. L., & Cormet-Boyaka, E. (2019). Cigarette and ENDS preparations differentially regulate ion channels and mucociliary clearance in primary normal human bronchial 3D cultures. AJP - Lung Mol Cell Phys, 317(2), L295\u2013L302.","journal-title":"AJP - Lung Mol Cell Phys"},{"issue":"12","key":"1042_CR29","doi-asserted-by":"publisher","first-page":"3263","DOI":"10.1158\/1055-9965.EPI-09-0965","volume":"18","author":"MD Johnson","year":"2009","unstructured":"Johnson, M. D., Schilz, J., Djordjevic, M. V., Rice, J. R., & Shields, P. G. (2009). Evaluation of in vitro assays for assessing the toxicity of cigarette smoke and smokeless tobacco. Cancer Epidemiol Biomarkers Prev, 18(12), 3263\u20133304.","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"1042_CR30","doi-asserted-by":"crossref","unstructured":"Rayner R. E., Makena P., Prasad G. L., Cormet-Boyaka E. Cigarette Smoke Preparations, Not Electronic Nicotine Delivery Systems (ENDS) Preparations, Induce Features of Lung Disease in a 3D Lung Repeat-Dose Model. In: AJP-Lung Cell Mol Physiol. vol. Epub ahead of print; 2020.","DOI":"10.1152\/ajplung.00452.2020"},{"issue":"3","key":"1042_CR31","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1093\/bioinformatics\/btw635","volume":"33","author":"Y Zhang","year":"2017","unstructured":"Zhang, Y., Xie, J., Yang, J., Fennell, A., Zhang, C., & Ma, Q. (2017). QUBIC: a bioconductor package for qualitative biclustering analysis of gene co-expression data. Bioinformatics, 33(3), 450\u2013452.","journal-title":"Bioinformatics"},{"issue":"12","key":"1042_CR32","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","volume":"15","author":"MI Love","year":"2014","unstructured":"Love, M. I., Huber, W., & Anders, S. (2014). Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Gen Biol, 15(12), 550.","journal-title":"Gen Biol"},{"issue":"W1","key":"1042_CR33","doi-asserted-by":"publisher","first-page":"W90","DOI":"10.1093\/nar\/gkw377","volume":"44","author":"MV Kuleshov","year":"2016","unstructured":"Kuleshov, M. V., Jones, M. R., Rouillard, A. D., Fernandez, N. F., Duan, Q., Wang, Z., Koplev, S., Jenkins, S. L., Jagodnik, K. M., & Lachmann, A. (2016). Enrichr: a comprehensive gene set enrichment analysis web server 2016 update. Nucleic Acids Research, 44(W1), W90\u2013W97.","journal-title":"Nucleic Acids Research"},{"issue":"D1","key":"1042_CR34","doi-asserted-by":"publisher","first-page":"D649","DOI":"10.1093\/nar\/gkx1132","volume":"46","author":"A Fabregat","year":"2018","unstructured":"Fabregat, A., Jupe, S., Matthews, L., Sidiropoulos, K., Gillespie, M., Garapati, P., Haw, R., Jassal, B., Korninger, F., & May, B. (2018). The reactome pathway knowledgebase. Nucleic Acids Research, 46(D1), D649\u2013D655.","journal-title":"Nucleic Acids Research"},{"issue":"5","key":"1042_CR35","doi-asserted-by":"publisher","first-page":"1739","DOI":"10.1007\/s00204-021-03008-0","volume":"95","author":"R Xiong","year":"2021","unstructured":"Xiong, R., Wu, Y., Wu, Q., Muskhelishvili, L., Davis, K., Tripathi, P., Chen, Y., Chen, T., Bryant, M., & Rosenfeldt, H., et al. (2021). Integration of transcriptome analysis with pathophysiological endpoints to evaluate cigarette smoke toxicity in an in vitro human airway tissue model. Arch Toxicol, 95(5), 1739\u20131761.","journal-title":"Arch Toxicol"},{"issue":"4","key":"1042_CR36","doi-asserted-by":"publisher","first-page":"647","DOI":"10.2174\/138920111795163995","volume":"12","author":"P Krishnamurthy","year":"2011","unstructured":"Krishnamurthy, P., & Schuetz, J. D. (2011). The role of ABCG2 and ABCB6 in porphyrin metabolism and cell survival. Curr Pharm Biotechnol, 12(4), 647\u2013655.","journal-title":"Curr Pharm Biotechnol"},{"issue":"3","key":"1042_CR37","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1016\/j.pharmthera.2007.02.001","volume":"114","author":"P Krishnamurthy","year":"2007","unstructured":"Krishnamurthy, P., Xie, T., & Schuetz, J. D. (2007). The role of transporters in cellular heme and porphyrin homeostasis. Pharmacol Ther, 114(3), 345\u2013358.","journal-title":"Pharmacol Ther"},{"issue":"7111","key":"1042_CR38","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1038\/nature05125","volume":"443","author":"PC Krishnamurthy","year":"2006","unstructured":"Krishnamurthy, P. C., Du, G., Fukuda, Y., Sun, D., Sampath, J., Mercer, K. E., Wang, J., Sosa-Pineda, B., Murti, K. G., & Schuetz, J. D. (2006). Identification of a mammalian mitochondrial porphyrin transporter. Nature, 443(7111), 586\u2013589.","journal-title":"Nature"},{"issue":"1","key":"1042_CR39","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1038\/s41421-021-00284-z","volume":"7","author":"G Song","year":"2021","unstructured":"Song, G., Zhang, S., Tian, M., Zhang, L., Guo, R., Zhuo, W., & Yang, M. (2021). Molecular insights into the human ABCB6 transporter. Cell Discov, 7(1), 55.","journal-title":"Cell Discov"},{"issue":"2","key":"1042_CR40","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.ccr.2004.06.026","volume":"6","author":"G Szakacs","year":"2004","unstructured":"Szakacs, G., Annereau, J. P., Lababidi, S., Shankavaram, U., Arciello, A., Bussey, K. J., Reinhold, W., Guo, Y., Kruh, G. D., & Reimers, M., et al. (2004). Predicting drug sensitivity and resistance: profiling ABC transporter genes in cancer cells. Cancer Cell, 6(2), 129\u2013137.","journal-title":"Cancer Cell"},{"issue":"2","key":"1042_CR41","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1093\/toxsci\/kfr008","volume":"120","author":"H Chavan","year":"2011","unstructured":"Chavan, H., Oruganti, M., & Krishnamurthy, P. (2011). The ATP-binding cassette transporter ABCB6 is induced by arsenic and protects against arsenic cytotoxicity. Toxicol Sci, 120(2), 519\u2013528.","journal-title":"Toxicol Sci"},{"issue":"1","key":"1042_CR42","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-018-36248-9","volume":"9","author":"JA Aguiar","year":"2019","unstructured":"Aguiar, J. A., Tamminga, A., Lobb, B., Huff, R. D., Nguyen, J. P., Kim, Y., Dvorkin-Gheva, A., Stampfli, M. R., Doxey, A. C., & Hirota, J. A. (2019). The impact of cigarette smoke exposure, COPD, or asthma status on ABC transporter gene expression in human airway epithelial cells. Scientific Reports, 9(1), 1\u201312.","journal-title":"Scientific Reports"},{"key":"1042_CR43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.neulet.2018.05.045","volume":"682","author":"MA Kaisar","year":"2018","unstructured":"Kaisar, M. A., Sivandzade, F., Bhalerao, A., & Cucullo, L. (2018). Conventional and electronic cigarettes dysregulate the expression of iron transporters and detoxifying enzymes at the brain vascular endothelium: In vivo evidence of a gender-specific cellular response to chronic cigarette smoke exposure. Neurosci Lett, 682, 1\u20139.","journal-title":"Neurosci Lett"},{"key":"1042_CR44","doi-asserted-by":"publisher","first-page":"118260","DOI":"10.1016\/j.lfs.2020.118260","volume":"259","author":"SP Lakshmi","year":"2020","unstructured":"Lakshmi, S. P., Reddy, A. T., Kodidhela, L. D., & Varadacharyulu, N. C. (2020). Epigallocatechin gallate diminishes cigarette smoke-induced oxidative stress, lipid peroxidation, and inflammation in human bronchial epithelial cells. Life Sciences, 259, 118260.","journal-title":"Life Sciences"},{"issue":"3","key":"1042_CR45","first-page":"273.","volume":"50","author":"A Venkatesan","year":"2006","unstructured":"Venkatesan, A., Hemalatha, A., Bobby, Z., Selvaraj, N., & Sathiyapriya, V. (2006). Effects of smoking on lipid profile and lipid peroxidation in normal subjects. Indian Journal of Physiology and Pharmacology, 50(3), 273.","journal-title":"Indian Journal of Physiology and Pharmacology"},{"issue":"3","key":"1042_CR46","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1007\/s10238-005-0072-5","volume":"5","author":"Z Solak","year":"2005","unstructured":"Solak, Z., Kabaro\u011flu, C., \u00c7ok, G., Par\u0131ldar, Z., Bay\u0131nd\u0131r, \u00dc., \u00d6zmen, D., & Bay\u0131nd\u0131r, O. (2005). Effect of different levels of cigarette smoking on lipid peroxidation, glutathione enzymes and paraoxonase 1 activity in healthy people. Clinical and Experimental Medicine, 5(3), 99\u2013105.","journal-title":"Clinical and Experimental Medicine"},{"issue":"2","key":"1042_CR47","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1158\/1055-9965.EPI-19-1245","volume":"29","author":"M-A Song","year":"2020","unstructured":"Song, M.-A., Freudenheim, J. L., Brasky, T. M., Mathe, E. A., McElroy, J. P., Nickerson, Q. A., Reisinger, S. A., Smiraglia, D. J., Weng, D. Y., & Ying, K. L. (2020). Biomarkers of Exposure and Effect in the Lungs of Smokers, Nonsmokers, and Electronic Cigarette Users. Cancer Epide Biomar, 29(2), 443\u2013451.","journal-title":"Cancer Epide Biomar"},{"key":"1042_CR48","doi-asserted-by":"crossref","unstructured":"Huang, J., Jiang, W., Tong, X., Zhang, L., Zhang, Y., & Fan, H.AC Identification of gene and microRNA changes in response to smoking in human airway epithelium by bioinformatics analyses. Medicine 2019, 98(38).","DOI":"10.1097\/MD.0000000000017267"},{"issue":"1","key":"1042_CR49","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41467-020-16239-z","volume":"11","author":"KC Goldfarbmuren","year":"2020","unstructured":"Goldfarbmuren, K. C., Jackson, N. D., Sajuthi, S. P., Dyjack, N., Li, K. S., Rios, C. L., Plender, E. G., Montgomery, M. T., Everman, J. L., & Bratcher, P. E. (2020). Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium. Nature Communications, 11(1), 1\u201321.","journal-title":"Nature Communications"}],"container-title":["Cell Biochemistry and Biophysics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12013-021-01042-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12013-021-01042-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12013-021-01042-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T06:53:28Z","timestamp":1675925608000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12013-021-01042-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,12]]},"references-count":49,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["1042"],"URL":"https:\/\/doi.org\/10.1007\/s12013-021-01042-4","relation":{},"ISSN":["1085-9195","1559-0283"],"issn-type":[{"value":"1085-9195","type":"print"},{"value":"1559-0283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,12]]},"assertion":[{"value":"23 July 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 October 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 November 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"P.M. and G.L.P. are employees of RAI Services Company. RAI Services Company is a wholly-owned subsidiary of Reynolds American, Inc. which is a wholly-owned subsidiary of British American Tobacco plc. R.E.R., J.W., J.Z., and E.C.B. declare that they have no competing financial interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}