{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T14:11:19Z","timestamp":1783951879000,"version":"3.55.0"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T00:00:00Z","timestamp":1713916800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T00:00:00Z","timestamp":1713916800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["30971674, 81470385 and 81770288"],"award-info":[{"award-number":["30971674, 81470385 and 81770288"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81870215"],"award-info":[{"award-number":["81870215"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013286","name":"Specialized Research Fund for the Doctoral Program of Higher Education of China","doi-asserted-by":"publisher","award":["200802460044"],"award-info":[{"award-number":["200802460044"]}],"id":[{"id":"10.13039\/501100013286","id-type":"DOI","asserted-by":"publisher"}]},{"name":"The Ninth Graduate Innovation Foundation of Fudan University","award":["The Ninth Graduate Innovation Foundation of Fudan University"],"award-info":[{"award-number":["The Ninth Graduate Innovation Foundation of Fudan University"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Stem Cell Rev and Rep"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1007\/s12015-024-10721-7","type":"journal-article","created":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T07:01:36Z","timestamp":1713942096000},"page":"1540-1554","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Delivery of Stem Cells and BMP-2 With Functionalized Self-Assembling Peptide Enhances Regeneration of Infarcted Myocardium"],"prefix":"10.1007","volume":"20","author":[{"given":"Hai-dong","family":"Guo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-hong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai-jie","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7848-2132","authenticated-orcid":false,"given":"Yu-zhen","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,24]]},"reference":[{"key":"10721_CR1","doi-asserted-by":"publisher","first-page":"E93","DOI":"10.1161\/CIR.0000000000001123","volume":"147","author":"CW Tsao","year":"2023","unstructured":"Tsao, C. W., Aday, A. W., Almarzooq, Z. I., Anderson, C. A. M., Arora, P., Avery, C. L., et al. (2023). Heart disease and stroke statistics\u20142023 update: A report from the American Heart Association. Circulation, 147, E93\u2013E621.","journal-title":"Circulation"},{"key":"10721_CR2","doi-asserted-by":"publisher","first-page":"H1406","DOI":"10.1152\/ajpheart.1991.260.5.H1406","volume":"260","author":"JM Pfeffer","year":"1991","unstructured":"Pfeffer, J. M., Pfeffer, M. A., Fletcher, P. J., & Braunwald, E. (1991). Progressive ventricular remodeling in rat with myocardial infarction. American Journal Physiology - Heart Circ Physiology, 260, H1406\u2013H1414.","journal-title":"American Journal Physiology - Heart Circ Physiology"},{"key":"10721_CR3","doi-asserted-by":"publisher","first-page":"2053","DOI":"10.1056\/NEJMra1606915","volume":"376","author":"JL Anderson","year":"2017","unstructured":"Anderson, J. L., & Morrow, D. A. (2017). Acute myocardial infarction. New England Journal of Medicine, 376, 2053\u20132064.","journal-title":"New England Journal of Medicine"},{"key":"10721_CR4","first-page":"e38","volume":"133","author":"D Mozaffarian","year":"2016","unstructured":"Mozaffarian, D., Benjamin, E. J., Go, A. S., Arnett, D. K., Blaha, M. J., Cushman, M., et al. (2016). Heart disease and stroke statistics\u20142016 update: A report from the American Heart Association. Circulation, 133, e38\u2013e360.","journal-title":"Circulation"},{"key":"10721_CR5","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.1161\/CIRCRESAHA.117.312486","volume":"122","author":"BA Tompkins","year":"2018","unstructured":"Tompkins, B. A., Balkan, W., Winkler, J., Gy\u00f6ngy\u00f6si, M., Goliasch, G., Fern\u00e1ndez-Avil\u00e9s, F., et al. (2018). Preclinical studies of stem cell therapy for heart disease. Circulation Research, 122, 1006\u20131020.","journal-title":"Circulation Research"},{"key":"10721_CR6","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1097\/CRD.0000000000000291","volume":"28","author":"J Rudman","year":"2020","unstructured":"Rudman, J., & Frishman, W. H. (2020). Stem cell therapy for acute myocardial infarctions: A systematic review. Cardiology in Review, 28, 140\u2013147.","journal-title":"Cardiology in Review"},{"key":"10721_CR7","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1161\/CIRCRESAHA.115.305373","volume":"118","author":"CP Hodgkinson","year":"2016","unstructured":"Hodgkinson, C. P., Bareja, A., Gomez, J. A., & Dzau, V. J. (2016). Emerging concepts in paracrine mechanisms in regenerative cardiovascular medicine and biology. Circulation Research, 118, 95\u2013107.","journal-title":"Circulation Research"},{"key":"10721_CR8","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1038\/s41536-017-0024-1","volume":"13","author":"E Cambria","year":"2017","unstructured":"Cambria, E., Pasqualini, F. S., Wolint, P., G\u00fcnter, J., Steiger, J., Bopp, A., et al. (2017). Translational cardiac stem cell therapy: Advancing from first-generation to next-generation cell types. Npj Regenerative Medicine, 13, 17.","journal-title":"Npj Regenerative Medicine"},{"key":"10721_CR9","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1093\/cvr\/cvab115","volume":"118","author":"D Thomas","year":"2022","unstructured":"Thomas, D., Cunningham, N. J., Shenoy, S., & Wu, J. C. (2022). Human-induced pluripotent stem cells in cardiovascular research: Current approaches in cardiac differentiation, maturation strategies, and scalable production. Cardiovascular Research, 118, 20\u201336.","journal-title":"Cardiovascular Research"},{"key":"10721_CR10","doi-asserted-by":"publisher","first-page":"1090","DOI":"10.3390\/cells12071090","volume":"12","author":"D Sridharan","year":"2023","unstructured":"Sridharan, D., Pracha, N., Rana, S. J., Ahmed, S., Dewani, A. J., Alvi, S. B., et al. (2023). Preclinical large animal porcine models for cardiac regeneration and its clinical translation: Role of hiPSC-derived cardiomyocytes. Cells, 12, 1090.","journal-title":"Cells"},{"key":"10721_CR11","doi-asserted-by":"publisher","first-page":"1413","DOI":"10.1161\/CIRCRESAHA.116.303614","volume":"116","author":"V Karantalis","year":"2015","unstructured":"Karantalis, V., & Hare, J. M. (2015). Use of mesenchymal stem cells for therapy of cardiac disease. Circulation Research, 116, 1413\u20131430.","journal-title":"Circulation Research"},{"key":"10721_CR12","doi-asserted-by":"publisher","first-page":"1546","DOI":"10.1007\/s12015-021-10314-8","volume":"18","author":"A Sharma","year":"2022","unstructured":"Sharma, A., Gupta, S., Archana, S., & Verma, R. S. (2022). Emerging trends in mesenchymal stem cells applications for cardiac regenerative therapy: Current status and advances. Stem Cell Reviews and Reports, 18, 1546\u20131602.","journal-title":"Stem Cell Reviews and Reports"},{"key":"10721_CR13","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1016\/S0092-8674(03)00687-1","volume":"114","author":"AP Beltrami","year":"2003","unstructured":"Beltrami, A. P., Barlucchi, L., Torella, D., Baker, M., Limana, F., Chimenti, S., et al. (2003). Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell, 114, 763\u2013776.","journal-title":"Cell"},{"key":"10721_CR14","doi-asserted-by":"publisher","first-page":"14068","DOI":"10.1073\/pnas.0706760104","volume":"104","author":"C Bearzi","year":"2007","unstructured":"Bearzi, C., Rota, M., Hosoda, T., Tillmanns, J., Nascimbene, A., De Angelis, A., et al. (2007). Human cardiac stem cells. Proceedings of the National Academy of Sciences of the United States of America, 104, 14068\u201314073.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10721_CR15","doi-asserted-by":"publisher","first-page":"1992","DOI":"10.1161\/CIRCULATIONAHA.109.909093","volume":"121","author":"MM Zaruba","year":"2010","unstructured":"Zaruba, M. M., Soonpaa, M., Reuter, S., & Field, L. J. (2010). Cardiomyogenic potential of c-kit+-expressing cells derived from neonatal and adult mouse hearts. Circulation, 121, 1992\u20132000.","journal-title":"Circulation"},{"key":"10721_CR16","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.ijcard.2018.01.134","volume":"265","author":"YL Wang","year":"2018","unstructured":"Wang, Y. L., Zhang, G. T., Wang, H. J., Tan, Y. Z., & Wang, X. Y. (2018). Preinduction with bone morphogenetic protein-2 enhances cardiomyogenic differentiation of c-kit+ mesenchymal stem cells and repair of infarcted myocardium. International Journal of Cardiology, 265, 173\u2013180.","journal-title":"International Journal of Cardiology"},{"key":"10721_CR17","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1038\/nrcardio.2014.9","volume":"11","author":"A Behfar","year":"2014","unstructured":"Behfar, A., Crespo-Diaz, R., Terzic, A., & Gersh, B. J. (2014). Cell therapy for cardiac repair\u2014lessons from clinical trials. Nature Reviews Cardiology, 11, 232\u2013246.","journal-title":"Nature Reviews Cardiology"},{"key":"10721_CR18","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1038\/s41587-019-0042-1","volume":"37","author":"KR Chien","year":"2019","unstructured":"Chien, K. R., Frisen, J., Fritsche-Danielson, R., Melton, D. A., Murry, C. E., & Weissman, I. L. (2019). Regenerating the field of cardiovascular cell therapy. Nature Biotechnology, 37, 232\u2013237.","journal-title":"Nature Biotechnology"},{"key":"10721_CR19","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1038\/nrcardio.2015.156","volume":"13","author":"NW Morrell","year":"2016","unstructured":"Morrell, N. W., Bloch, D. B., Dijke, P., Goumans, M. J. T. H., Hata, A., Smith, J., et al. (2016). Targeting BMP signalling in cardiovascular disease and anaemia. Nature Reviews Cardiology, 13, 106\u2013120.","journal-title":"Nature Reviews Cardiology"},{"key":"10721_CR20","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1242\/dev.109.4.833","volume":"109","author":"KM Lyons","year":"1990","unstructured":"Lyons, K. M., Pelton, R. W., & Hogan, B. L. (1990). Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein-2A (BMP-2A). Development, 109, 833\u2013844.","journal-title":"Development"},{"key":"10721_CR21","doi-asserted-by":"publisher","first-page":"2977","DOI":"10.1242\/dev.122.10.2977","volume":"122","author":"H Zhang","year":"1996","unstructured":"Zhang, H., & Bradley, A. (1996). Mice deficient for BMP2 are nonviable and have defects in amnion\/chorion and cardiac development. Development, 122, 2977\u20132986.","journal-title":"Development"},{"key":"10721_CR22","doi-asserted-by":"publisher","first-page":"1558","DOI":"10.1096\/fj.02-0072com","volume":"16","author":"A Behfar","year":"2002","unstructured":"Behfar, A., Zingman, L. V., Hodgson, D. M., Rauzier, J. M., Kane, G. C., Terzic, A., et al. (2002). Stem cell differentiation requires a paracrine pathway in the heart. FASEB Journal, 16, 1558\u20131566.","journal-title":"FASEB Journal"},{"key":"10721_CR23","doi-asserted-by":"publisher","first-page":"21998","DOI":"10.1074\/jbc.M302277200","volume":"278","author":"N Ghosh-Choudhury","year":"2003","unstructured":"Ghosh-Choudhury, N., Abboud, S. L., Mahimainathan, L., Chandrasekar, B., & Choudhury, G. G. (2003). Phosphatidylinositol 3-kinase regulates bone morphogenetic protein-2 (BMP-2)-induced myocyte enhancer factor 2A-dependent transcription of BMP-2 gene in cardiomyocyte precursor cells. Journal Biological Chemistry, 278, 21998\u201322005.","journal-title":"Journal Biological Chemistry"},{"key":"10721_CR24","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1089\/ten.tea.2010.0124","volume":"17","author":"HD Guo","year":"2011","unstructured":"Guo, H. D., Wang, H. J., Tan, Y. Z., & Wu, J. H. (2011). Transplantation of marrow-derived cardiac stem cells carried in fibrin improves cardiac function after myocardial infarction. Tissue Engineering Part A, 17, 45\u201358.","journal-title":"Tissue Engineering Part A"},{"key":"10721_CR25","doi-asserted-by":"publisher","first-page":"1650","DOI":"10.1002\/stem.3445","volume":"39","author":"HJ Park","year":"2021","unstructured":"Park, H. J., De Jesus Morales, K. J., Bheri, S., Kassouf, B. P., & Davis, M. E. (2021). Bidirectional relationship between cardiac extracellular matrix and cardiac cells in ischemic heart disease. Stem Cells, 39, 1650\u20131659.","journal-title":"Stem Cells"},{"key":"10721_CR26","doi-asserted-by":"publisher","first-page":"13434","DOI":"10.1021\/acs.chemrev.0c00690","volume":"120","author":"F Gelain","year":"2020","unstructured":"Gelain, F., Luo, Z., & Zhang, S. (2020). Self-assembling peptide EAK16 and RADA16 nanofiber scaffold hydrogel. Chemical Reviews, 120, 13434\u201313460.","journal-title":"Chemical Reviews"},{"key":"10721_CR27","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1038\/s41536-020-00116-w","volume":"6","author":"F Gelain","year":"2021","unstructured":"Gelain, F., Luo, Z., Rioult, M., & Zhang, S. (2021). Self-assembling peptide scaffolds in the clinic. Npj Regenerative Medicine, 6, 9.","journal-title":"Npj Regenerative Medicine"},{"key":"10721_CR28","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.addr.2015.04.023","volume":"96","author":"KM French","year":"2016","unstructured":"French, K. M., Somasuntharam, I., & Davis, M. E. (2016). Self-assembling peptide-based delivery of therapeutics for myocardial infarction. Advanced Drug Delivery Reviews, 96, 40\u201353.","journal-title":"Advanced Drug Delivery Reviews"},{"key":"10721_CR29","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/j.addr.2021.04.024","volume":"174","author":"C Karavasili","year":"2021","unstructured":"Karavasili, C., & Fatouros, D. G. (2021). Self-assembling peptides as vectors for local drug delivery and tissue engineering applications. Advanced Drug Delivery Reviews, 174, 387\u2013405.","journal-title":"Advanced Drug Delivery Reviews"},{"key":"10721_CR30","doi-asserted-by":"publisher","first-page":"1596","DOI":"10.1038\/nprot.2006.188","volume":"1","author":"NF Huang","year":"2006","unstructured":"Huang, N. F., Sievers, R. E., Park, J. S., Fang, Q., Li, S., & Lee, R. J. (2006). A rodent model of myocardial infarction for testing the efficacy of cells and polymers for myocardial reconstruction. Nature Protocols, 1, 1596\u20131609.","journal-title":"Nature Protocols"},{"key":"10721_CR31","doi-asserted-by":"publisher","first-page":"8414","DOI":"10.1073\/pnas.0407843102","volume":"102","author":"H Yokoi","year":"2005","unstructured":"Yokoi, H., Kinoshita, T., & Zhang, S. (2005). Dynamic reassembly of peptide RADA16 nanofiber scaffold. Proceedings of the National Academy of Sciences of the United States of America, 102, 8414\u20138419.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10721_CR32","doi-asserted-by":"publisher","first-page":"1367","DOI":"10.1089\/scd.2011.0280","volume":"21","author":"JH Wu","year":"2012","unstructured":"Wu, J. H., Wang, H. J., Tan, Y. Z., & Li, Z. H. (2012). Characterization of rat very small embryonic-like stem cells and cardiac repair after cell transplantation for myocardial infarction. Stem Cells and Development, 21, 1367\u20131379.","journal-title":"Stem Cells and Development"},{"key":"10721_CR33","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1038\/s41419-018-0442-z","volume":"9","author":"B Prados","year":"2018","unstructured":"Prados, B., G\u00f3mez-Api\u00f1\u00e1niz, P., Papoutsi, T., Lux\u00e1n, G., Zaffran, S., P\u00e9rez-Pomares, J. M., et al. (2018). Myocardial Bmp2 gain causes ectopic EMT and promotes cardiomyocyte proliferation and immaturity. Cell Death and Disease, 9, 399.","journal-title":"Cell Death and Disease"},{"key":"10721_CR34","doi-asserted-by":"publisher","first-page":"103031","DOI":"10.1016\/j.jbc.2023.103031","volume":"299","author":"S Das","year":"2023","unstructured":"Das, S., Mondal, A., Dey, C., Chakraborty, S., Bhowmik, R., Karmakar, S., et al. (2023). ER stress induces upregulation of transcription factor Tbx20 and downstream Bmp2 signaling to promote cardiomyocyte survival. Journal of Biological Chemistry, 299, 103031.","journal-title":"Journal of Biological Chemistry"},{"key":"10721_CR35","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.1093\/cvr\/cvaa287","volume":"117","author":"X Wu","year":"2021","unstructured":"Wu, X., Reboll, M. R., Korf-Klingebiel, M., & Wollert, K. C. (2021). Angiogenesis after acute myocardial infarction. Cardiovascular Research, 117, 1257\u20131273.","journal-title":"Cardiovascular Research"},{"key":"10721_CR36","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1161\/01.CIR.0000153847.47301.80","volume":"111","author":"ME Davis","year":"2005","unstructured":"Davis, M. E., Motion, J. P. M., Narmoneva, D. A., Takahashi, T., Hakuno, D., Kamm, R. D., et al. (2005). Injectable self-assembling peptide nanofibers create intramyocardial microenvironments for endothelial cells. Circulation, 111, 442\u2013450.","journal-title":"Circulation"},{"key":"10721_CR37","doi-asserted-by":"publisher","first-page":"130145","DOI":"10.1016\/j.cej.2021.130145","volume":"422","author":"Z Siddiqui","year":"2021","unstructured":"Siddiqui, Z., Sarkar, B., Kim, K. K., Kumar, A., Paul, R., Mahajan, A., et al. (2021). Self-assembling peptide hydrogels facilitate vascularization in two-component scaffolds. Chemical Engineering Journal, 422, 130145.","journal-title":"Chemical Engineering Journal"},{"key":"10721_CR38","doi-asserted-by":"publisher","first-page":"3126","DOI":"10.1038\/s41375-020-01041-z","volume":"34","author":"MZ Ratajczak","year":"2020","unstructured":"Ratajczak, M. Z., & Ratajczak, J. (2020). Extracellular microvesicles\/exosomes: Discovery, disbelief, acceptance, and the future? Leukemia, 34, 3126\u20133135.","journal-title":"Leukemia"},{"key":"10721_CR39","doi-asserted-by":"publisher","first-page":"113766","DOI":"10.1016\/j.yexcr.2023.113766","volume":"431","author":"B Bakhshandeh","year":"2023","unstructured":"Bakhshandeh, B., Sorboni, S. G., Ranjbar, N., Deyhimfar, R., Abtahi, M. S., Izady, M., et al. (2023). Mechanotransduction in tissue engineering: Insights into the interaction of stem cells with biomechanical cues. Experimental Cell Research, 431, 113766.","journal-title":"Experimental Cell Research"},{"key":"10721_CR40","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1097\/SHK.0b013e318289728a","volume":"39","author":"H Ebelt","year":"2013","unstructured":"Ebelt, H., Hillebrand, I., Arlt, S., Zhang, Y., Kostin, S., Neuhaus, H., et al. (2013). Treatment with bone morphogenetic protein 2 limits infarct size after myocardial infarction in mice. Shock (Augusta, Ga.), 39, 353\u2013360.","journal-title":"Shock (Augusta, Ga.)"},{"key":"10721_CR41","doi-asserted-by":"publisher","first-page":"4262","DOI":"10.7150\/thno.52309","volume":"11","author":"YL Wang","year":"2021","unstructured":"Wang, Y. L., Yu, S. N., Shen, H. R., Wang, H. J., Wu, X. P., Wang, Q. L., et al. (2021). Thymosin \u03b24 released from functionalized self-assembling peptide activates epicardium and enhances repair of infarcted myocardium. Theranostics, 11, 4262\u20134280.","journal-title":"Theranostics"},{"key":"10721_CR42","doi-asserted-by":"publisher","first-page":"113440","DOI":"10.1016\/j.yexcr.2022.113440","volume":"422","author":"YZ Tan","year":"2023","unstructured":"Tan, Y. Z., Shen, H. R., Wang, Y. L., Wang, Q. L., Wu, X. P., Yu, S. N., et al. (2023). Retinoic acid released from self-assembling peptide activates cardiomyocyte proliferation and enhances repair of infarcted myocardium. Experimental Cell Research, 422, 113440.","journal-title":"Experimental Cell Research"},{"key":"10721_CR43","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1007\/s12015-022-10430-z","volume":"19","author":"P Zhou","year":"2023","unstructured":"Zhou, P., Yu, S. N., Zhang, H. F., Wang, Y. L., Tao, P., Tan, Y. Z., et al. (2023). c-kit+VEGFR-2+ mesenchymal stem cells differentiate into cardiovascular cells and repair infarcted myocardium after transplantation. Stem Cell Reviews and Reports, 19, 230\u2013247.","journal-title":"Stem Cell Reviews and Reports"}],"container-title":["Stem Cell Reviews and Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12015-024-10721-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12015-024-10721-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12015-024-10721-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T11:57:56Z","timestamp":1723463876000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12015-024-10721-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,24]]},"references-count":43,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10721"],"URL":"https:\/\/doi.org\/10.1007\/s12015-024-10721-7","relation":{},"ISSN":["2629-3269","2629-3277"],"issn-type":[{"value":"2629-3269","type":"print"},{"value":"2629-3277","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,24]]},"assertion":[{"value":"4 April 2024","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 April 2024","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All animal studies were performed in accordance with relevant guidelines from the Directive 2010\/63\/EU of the European Parliament on the protection of animals used for scientific purposes. The investigation was permitted by the Law of the People\u2019s Republic of China on the Protection of Wildlife and approved by the Committee for Animal Care and Ethical Review at Fudan University (SYXK 2009\u20130082).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"All authors have read the final version of this manuscript and agree with its publication.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Publish"}},{"value":"The authors declare that they have no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}