{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T13:39:53Z","timestamp":1770989993750,"version":"3.50.1"},"reference-count":5,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T00:00:00Z","timestamp":1739318400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T00:00:00Z","timestamp":1739318400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Stem Cell Rev and Rep"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1007\/s12015-025-10854-3","type":"journal-article","created":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T12:40:18Z","timestamp":1739364018000},"page":"897-899","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["FBXL4-Related Mitochondrial Depletion Syndrome Underscores the role of Mitophagy in Stem Cell Differentiation during Embryogenesis"],"prefix":"10.1007","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5949-6421","authenticated-orcid":false,"given":"Pankaj","family":"Prasun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,2,12]]},"reference":[{"key":"10854_CR1","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1038\/s41392-023-01503-7","volume":"8","author":"S Wang","year":"2023","unstructured":"Wang, S., Long, H., Hou, L., Feng, B., Ma, Z., Wu, Y., Zeng, Y., Cai, J., Zhang, D. W., & Zhao, G. (2023). The mitophagy pathway and its implications in human diseases. Signal Transduction and Targeted Therapy, 8, 304. https:\/\/doi.org\/10.1038\/s41392-023-01503-7","journal-title":"Signal Transduction and Targeted Therapy"},{"key":"10854_CR2","doi-asserted-by":"publisher","first-page":"481","DOI":"10.3390\/biology9120481","volume":"9","author":"G Cairns","year":"2020","unstructured":"Cairns, G., Thumiah-Mootoo, M., Burelle, Y., & Khacho, M. (2020). Mitophagy: A New Player in Stem Cell Biology. Biology, 9, 481. https:\/\/doi.org\/10.3390\/biology9120481","journal-title":"Biology"},{"key":"10854_CR3","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1186\/s12967-024-05633-6","volume":"22","author":"A Adelizzi","year":"2024","unstructured":"Adelizzi, A., Giri, A., Di Donfrancesco, A., Boito, S., Prigione, A., Bottani, E., Bollati, V., Tiranti, V., Persico, N., & Brunetti, D. (2024). Fetal and obstetrics manifestations of mitochondrial diseases. Journal of Translational Medicine, 22, 853. https:\/\/doi.org\/10.1186\/s12967-024-05633-6","journal-title":"Journal of Translational Medicine"},{"key":"10854_CR4","doi-asserted-by":"publisher","unstructured":"Alsina, D., Lytovchenko, O., Schab, A., Atanassov, I., Schober, F. A., Jiang, M., Koolmeister, C., Wedell, A., Taylor, R. W., Wredenberg, A., & Larsson, N. G. (2020). FBXL4 deficiency increases mitochondrial removal by autophagy. EMBO Molecular Medicine, 12, e11659. https:\/\/doi.org\/10.15252\/emmm.201911659","DOI":"10.15252\/emmm.201911659"},{"key":"10854_CR5","doi-asserted-by":"publisher","unstructured":"Huemer, M., Karall, D., Schossig, A., Abdenur, J. E., Al Jasmi, F., Biagosch, C.,Distelmaier, F., Freisinger, P., Graham, B. H., Haack, T. B., Hauser, N., Hertecant,J., Ebrahimi-Fakhari, D., Konstantopoulou, V., Leydiker, K., Lourenco, C. M., Scholl-B\u00fcrgi,S., Wilichowski, E., Wolf, N. I., Wortmann, S. B.,\u2026 McFarland, R. (2015) Clinical,morphological, biochemical, imaging and outcome parameters in 21 individuals with mitochondrial maintenance defect related to FBXL4 mutations. Journal of Inherited Metabolic Disease, 38, 905\u2013914. https:\/\/doi.org\/10.1007\/s10545-015-9836-6","DOI":"10.1007\/s10545-015-9836-6"}],"container-title":["Stem Cell Reviews and Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12015-025-10854-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12015-025-10854-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12015-025-10854-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T21:11:53Z","timestamp":1743628313000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12015-025-10854-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,12]]},"references-count":5,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10854"],"URL":"https:\/\/doi.org\/10.1007\/s12015-025-10854-3","relation":{},"ISSN":["2629-3269","2629-3277"],"issn-type":[{"value":"2629-3269","type":"print"},{"value":"2629-3277","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,12]]},"assertion":[{"value":"8 February 2025","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 February 2025","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This report is a retrospective clinical observation that does not require ethics committee approval at this institution.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statement of Ethics"}},{"value":"The author has no relevant financial or non-financial interests to disclose.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}