{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T21:19:12Z","timestamp":1791235152909,"version":"4.1.0"},"reference-count":147,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:00:00Z","timestamp":1747180800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:00:00Z","timestamp":1747180800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e0 degli Studi di Roma La Sapienza"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Stem Cell Rev and Rep"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>Amniotic membrane transplantation (AMT) has emerged as a versatile therapeutic modality with significant applications in wound healing, tissue regeneration, and ophthalmology. This review comprehensively evaluates AMT's efficacy in acute and chronic wound management, where it has been shown to alleviate pain, reduce infection risk, and facilitate epithelialization. In chronic wounds, AMT enhances healing through mechanisms such as re-epithelialization, angiogenesis, and immune modulation. Additionally, AMT exhibits promise in nerve regeneration, demonstrating potential in the repair of peripheral and central nervous system injuries by fostering neural recovery and minimizing scar formation. In ophthalmology, AMT is instrumental in corneal surface reconstruction, conjunctival repairs, and the management of dry eye syndrome and limbal stem cell deficiency. While the benefits of AMT are well-documented, this review also addresses significant challenges, including variability in success rates across different clinical conditions, ethical concerns regarding donor tissue usage, and regulatory hurdles impacting its broader clinical application. Furthermore, we integrate recent advances in the understanding of AMT's molecular mechanisms \u2013 such as its antioxidant effects via Nrf2\/HO-1 pathway and immune modulation via P2X7 receptor pathways \u2013 and highlight innovative strategies including the incorporation of nanoceria nanoparticles, Vitamin D3 supplementation, and gene therapy approaches to enhance AMT outcomes. By exploring these dimensions, the review highlights not only the current state of AMT but also its potential future role in advancing regenerative medicine, including emerging applications in spinal cord repair, orthopaedics, and tissue engineering. This updated synthesis aims to inform clinicians and researchers about the multifaceted applications of AMT, promoting further investigation and optimization of this promising therapeutic approach.<\/jats:p>\n          <jats:p>\n            <jats:bold>Graphical Abstract<\/jats:bold>\n          <\/jats:p>","DOI":"10.1007\/s12015-025-10892-x","type":"journal-article","created":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T03:23:28Z","timestamp":1747193008000},"page":"1428-1448","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Amniotic Membrane Transplantation for Wound Healing, Tissue Regeneration and Immune Modulation"],"prefix":"10.1007","volume":"21","author":[{"given":"Uday Pratap Singh","family":"Parmar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7721-4694","authenticated-orcid":false,"given":"Pier Luigi","family":"Surico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Scarabosio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Barone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohan Bir","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"D\u2019Ancona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Zeppieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pier Camillo","family":"Parodi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommaso","family":"Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Cutrupi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David Hui-Kang","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Di Zazzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Coassin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,5,14]]},"reference":[{"issue":"2","key":"10892_CR1","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1007\/s00441-012-1424-6","volume":"349","author":"AC Mamede","year":"2012","unstructured":"Mamede, A. C., Carvalho, M. J., Abrantes, A. M., Laranjo, M., Maia, C. J., & Botelho, M. F. (2012). Amniotic membrane: From structure and functions to clinical applications. Cell and Tissue Research, 349(2), 447\u2013458. https:\/\/doi.org\/10.1007\/s00441-012-1424-6","journal-title":"Cell and Tissue Research"},{"issue":"3","key":"10892_CR2","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1097\/00000658-190909000-00002","volume":"50","author":"JS Davis","year":"1909","unstructured":"Davis, J. S. (1909). Skin grafting at the johns hopkins hospital. Annals of Surgery, 50(3), 542\u2013549. https:\/\/doi.org\/10.1097\/00000658-190909000-00002","journal-title":"Annals of Surgery"},{"key":"10892_CR3","unstructured":"Sabella, N. (1913). Use of fetal membranes in skin grafting. Medication Reconciliation in New York, 83, 478. Retrieved from https:\/\/cir.nii.ac.jp\/crid\/1573387449063012608.bib?lang=en"},{"issue":"3","key":"10892_CR4","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1001\/archopht.1940.00860130586006","volume":"23","author":"A de Rotth","year":"1940","unstructured":"de Rotth, A. (1940). Plastic repair of conjunctival defects with fetal membranes. Archives of Ophthalmology, 23(3), 522\u2013525. https:\/\/doi.org\/10.1001\/archopht.1940.00860130586006","journal-title":"Archives of Ophthalmology"},{"issue":"5","key":"10892_CR5","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1097\/00003226-199509000-00006","volume":"14","author":"JC Kim","year":"1995","unstructured":"Kim, J. C., & Tseng, S. C. (1995). Transplantation of preserved human amniotic membrane for surface reconstruction in severely damaged rabbit corneas. Cornea, 14(5), 473\u2013484.","journal-title":"Cornea"},{"issue":"6","key":"10892_CR6","doi-asserted-by":"publisher","first-page":"1070","DOI":"10.1016\/0002-9378(60)90512-3","volume":"79","author":"GL Bourne","year":"1960","unstructured":"Bourne, G. L. (1960). The microscopic anatomy of the human amnion and chorion. American Journal of Obstetrics and Gynecology, 79(6), 1070\u20131073. https:\/\/doi.org\/10.1016\/0002-9378(60)90512-3","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"2","key":"10892_CR7","doi-asserted-by":"publisher","first-page":"111","DOI":"10.5500\/wjt.v4.i2.111","volume":"4","author":"C Malhotra","year":"2014","unstructured":"Malhotra, C., & Jain, A. K. (2014). Human amniotic membrane transplantation: Different modalities of its use in ophthalmology. World Journal of Transplantation, 4(2), 111. https:\/\/doi.org\/10.5500\/wjt.v4.i2.111","journal-title":"World Journal of Transplantation"},{"issue":"3","key":"10892_CR8","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1111\/j.1471-0528.1979.tb10598.x","volume":"86","author":"SM Pollard","year":"1979","unstructured":"Pollard, S. M., Symonds, E. M., & Aye, N. N. (1979). Scanning electron microscopic appearances in the amnion in polyhydramnios and oligohydramnios. BJOG: An International Journal of Obstetrics & Gynaecology, 86(3), 228\u2013232. https:\/\/doi.org\/10.1111\/j.1471-0528.1979.tb10598.x","journal-title":"BJOG: An International Journal of Obstetrics & Gynaecology"},{"issue":"1","key":"10892_CR9","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1053\/j.jfas.2018.08.014","volume":"58","author":"TB Bemenderfer","year":"2019","unstructured":"Bemenderfer, T. B., Anderson, R. B., Odum, S. M., & Davis, W. H. (2019). Effects of cryopreserved amniotic membrane-umbilical cord allograft on total ankle arthroplasty wound healing. The Journal of Foot and Ankle Surgery, 58(1), 97\u2013102. https:\/\/doi.org\/10.1053\/j.jfas.2018.08.014","journal-title":"The Journal of Foot and Ankle Surgery"},{"issue":"12","key":"10892_CR10","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1080\/00914037.2019.1626388","volume":"69","author":"R Ramakrishnan","year":"2020","unstructured":"Ramakrishnan, R., Krishnan, L. K., Nair, R. P., & Kalliyana Krishnan, V. (2020). Reinforcement of amniotic membrane with fibrin coated poly-[Lactide-co-Glycolide-co-Caprolactone] terpolymer containing silver nanoparticles for potential wound healing applications. International Journal of Polymeric Materials and Polymeric Biomaterials, 69(12), 810\u2013819. https:\/\/doi.org\/10.1080\/00914037.2019.1626388","journal-title":"International Journal of Polymeric Materials and Polymeric Biomaterials"},{"issue":"8","key":"10892_CR11","doi-asserted-by":"publisher","first-page":"872","DOI":"10.1016\/S0002-9378(16)33135-0","volume":"131","author":"BJ van Herendael","year":"1978","unstructured":"van Herendael, B. J., Oberti, C., & Brosens, I. (1978). Microanatomy of the human amniotic membranes. American Journal of Obstetrics and Gynecology, 131(8), 872\u2013880. https:\/\/doi.org\/10.1016\/S0002-9378(16)33135-0","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"3","key":"10892_CR12","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1076\/0271-3683(200003)2031-9FT173","volume":"20","author":"NJ Koizumi","year":"2000","unstructured":"Koizumi, N. J., Inatomi, T. J., Sotozono, C. J., Fullwood, N. J., Quantock, A. J., & Kinoshita, S. (2000). Growth factor mRNA and protein in preserved human amniotic membrane. Current Eye Research, 20(3), 173\u2013177.","journal-title":"Current Eye Research"},{"issue":"2","key":"10892_CR13","doi-asserted-by":"publisher","first-page":"174","DOI":"10.3109\/02713683.2016.1164189","volume":"42","author":"M Bischoff","year":"2017","unstructured":"Bischoff, M., Stachon, T., Seitz, B., Huber, M., Zawada, M., Langenbucher, A., & Szentm\u00e1ry, N. (2017). Growth factor and Interleukin concentrations in amniotic membrane-conditioned medium. Current Eye Research, 42(2), 174\u2013180. https:\/\/doi.org\/10.3109\/02713683.2016.1164189","journal-title":"Current Eye Research"},{"issue":"8","key":"10892_CR14","doi-asserted-by":"publisher","first-page":"1216","DOI":"10.1002\/jbm.a.37509","volume":"111","author":"M Laleh","year":"2023","unstructured":"Laleh, M., Tahernejad, M., Bonakdar, S., Asefnejad, A., Golkar, M., Kazemi-Lomedasht, F., & Habibi-Anbouhi, M. (2023). Positive effect of acellular amniotic membrane dressing with immobilized growth factors in skin wound healing. Journal of Biomedical Materials Research Part A, 111(8), 1216\u20131227. https:\/\/doi.org\/10.1002\/jbm.a.37509","journal-title":"Journal of Biomedical Materials Research Part A"},{"issue":"12","key":"10892_CR15","doi-asserted-by":"publisher","first-page":"2115","DOI":"10.1089\/scd.2011.0031","volume":"20","author":"B Kronsteiner","year":"2011","unstructured":"Kronsteiner, B., Wolbank, S., Peterbauer, A., Hackl, C., Redl, H., van Griensven, M., & Gabriel, C. (2011). Human mesenchymal stem cells from adipose tissue and amnion influence T-cells depending on stimulation method and presence of other immune cells. Stem Cells and Development, 20(12), 2115\u20132126. https:\/\/doi.org\/10.1089\/scd.2011.0031","journal-title":"Stem Cells and Development"},{"issue":"24","key":"10892_CR16","doi-asserted-by":"publisher","first-page":"8357","DOI":"10.1073\/pnas.0803341105","volume":"105","author":"S Liang","year":"2008","unstructured":"Liang, S., Ristich, V., Arase, H., Dausset, J., Carosella, E. D., & Horuzsko, A. (2008). Modulation of dendritic cell differentiation by HLA-G and ILT4 requires the IL-6\u2014STAT3 signaling pathway. Proceedings of the National Academy of Sciences, 105(24), 8357\u20138362. https:\/\/doi.org\/10.1073\/pnas.0803341105","journal-title":"Proceedings of the National Academy of Sciences"},{"key":"10892_CR17","doi-asserted-by":"publisher","unstructured":"Lebreton, F., Lavallard, V., Bellofatto, K., Bonnet, R., Wassmer, C. H., Perez, L., \u2026 Berishvili, E. (2019). Insulin-producing organoids engineered from islet and amniotic epithelial cells to treat diabetes. Nature Communications, 10(1), 4491. https:\/\/doi.org\/10.1038\/s41467-019-12472-3","DOI":"10.1038\/s41467-019-12472-3"},{"key":"10892_CR18","doi-asserted-by":"publisher","unstructured":"Wu, W., Lan, Q., Lu, H., Xu, J., Zhu, A., Fang, W., \u2026 Hui, G. (2014). Human amnion mesenchymal cells negative co-stimulatory molecules PD-L1 expression and its capacity of modulating microglial activation of CNS. Cell Biochemistry and Biophysics, 69(1), 35\u201345. https:\/\/doi.org\/10.1007\/s12013-013-9763-9","DOI":"10.1007\/s12013-013-9763-9"},{"issue":"1","key":"10892_CR19","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1097\/TP.0000000000000169","volume":"98","author":"N Murakami","year":"2014","unstructured":"Murakami, N., & Riella, L. V. (2014). Co-inhibitory pathways and their importance in immune regulation. Transplantation, 98(1), 3\u201314. https:\/\/doi.org\/10.1097\/TP.0000000000000169","journal-title":"Transplantation"},{"issue":"3","key":"10892_CR20","doi-asserted-by":"publisher","first-page":"900","DOI":"10.1167\/iovs.04-0495","volume":"46","author":"H Li","year":"2005","unstructured":"Li, H., Niederkorn, J. Y., Neelam, S., Mayhew, E., Word, R. A., McCulley, J. P., & Alizadeh, H. (2005). Immunosuppressive factors secreted by human amniotic epithelial cells. Investigative Opthalmology & Visual Science, 46(3), 900. https:\/\/doi.org\/10.1167\/iovs.04-0495","journal-title":"Investigative Opthalmology & Visual Science"},{"key":"10892_CR21","doi-asserted-by":"publisher","unstructured":"Magatti, M., Vertua, E., De Munari, S., Caro, M., Caruso, M., Silini, A., \u2026 Parolini, O. (2017). Human amnion favours tissue repair by inducing the M1-to-M2 switch and enhancing M2 macrophage features. Journal of Tissue Engineering and Regenerative Medicine, 11(10), 2895\u20132911. https:\/\/doi.org\/10.1002\/term.2193","DOI":"10.1002\/term.2193"},{"issue":"10","key":"10892_CR22","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1136\/bjo.87.10.1215","volume":"87","author":"A Heiligenhaus","year":"2003","unstructured":"Heiligenhaus, A. (2003). Management of acute ulcerative and necrotising herpes simplex and zoster keratitis with amniotic membrane transplantation. British Journal of Ophthalmology, 87(10), 1215\u20131219. https:\/\/doi.org\/10.1136\/bjo.87.10.1215","journal-title":"British Journal of Ophthalmology"},{"issue":"3","key":"10892_CR23","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1002\/(SICI)1097-4652(199906)179:3\/325::AID-JCP10\/3.0.CO;2-X","volume":"179","author":"SC Tseng","year":"1999","unstructured":"Tseng, S. C., Li, D. Q., & Ma, X. (1999). Suppression of transforming growth factor-beta isoforms, TGF-beta receptor type II, and myofibroblast differentiation in cultured human corneal and limbal fibroblasts by amniotic membrane matrix. Journal of cellular physiology, 179(3), 325\u2013335. https:\/\/doi.org\/10.1002\/(SICI)1097-4652(199906)179:3\/325::AID-JCP10\/3.0.CO;2-X","journal-title":"Journal of cellular physiology"},{"key":"10892_CR24","doi-asserted-by":"publisher","unstructured":"Faridvand, Y., Nozari, S., Vahedian, V., Safaie, N., Pezeshkian, M., Haddadi, P., \u2026 Nouri, M. (2019). Nrf2 activation and down-regulation of HMGB1 and MyD88 expression by amnion membrane extracts in response to the hypoxia-induced injury in cardiac H9c2 cells. Biomedicine & Pharmacotherapy, 109, 360\u2013368. https:\/\/doi.org\/10.1016\/j.biopha.2018.10.035","DOI":"10.1016\/j.biopha.2018.10.035"},{"key":"10892_CR25","doi-asserted-by":"publisher","unstructured":"Fresta, C. G., Caruso, G., Fidilio, A., Platania, C. B. M., Musso, N., Caraci, F., \u2026 Bucolo, C. (2020). Dihydrotanshinone, a Natural Diterpenoid, Preserves Blood-Retinal Barrier Integrity via P2X7 Receptor. International Journal of Molecular Sciences, 21(23), 9305. https:\/\/doi.org\/10.3390\/ijms21239305","DOI":"10.3390\/ijms21239305"},{"key":"10892_CR26","doi-asserted-by":"publisher","unstructured":"Choudhary, N., Kumar, A., Priyadarshini, P., Bagaria, D., Alam, J., Soni, K. D., \u2026 Mohanty, S. (2023). Revisiting the role of amniotic membrane dressing in acute large traumatic wounds: A randomized feasibility study at a level 1 trauma centre. Journal of Emergencies, Trauma, and Shock. https:\/\/doi.org\/10.4103\/jets.jets_17_23","DOI":"10.4103\/jets.jets_17_23"},{"key":"10892_CR27","doi-asserted-by":"publisher","unstructured":"Meller, D., Pires, R. T. F., Mack, R. J. S., Figueiredo, F., Heiligenhaus, A., Park, W. C., \u2026 Tseng, S. C. G. (2000). Amniotic membrane transplantation for acute chemical or thermal burns. Ophthalmology, 107(5), 980\u2013989. https:\/\/doi.org\/10.1016\/S0161-6420(00)00024-5","DOI":"10.1016\/S0161-6420(00)00024-5"},{"key":"10892_CR28","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.ajo.2018.11.001","volume":"199","author":"M Eslani","year":"2019","unstructured":"Eslani, M., Baradaran-Rafii, A., Cheung, A. Y., Kurji, K. H., Hasani, H., Djalilian, A. R., & Holland, E. J. (2019). Amniotic membrane transplantation in acute severe ocular chemical injury: A randomized clinical trial. American Journal of Ophthalmology, 199, 209\u2013215. https:\/\/doi.org\/10.1016\/j.ajo.2018.11.001","journal-title":"American Journal of Ophthalmology"},{"key":"10892_CR29","doi-asserted-by":"publisher","unstructured":"Clare, G., Bunce, C., & Tuft, S. (2022). Amniotic membrane transplantation for acute ocular burns. Cochrane Database of Systematic Reviews, 2022(9). https:\/\/doi.org\/10.1002\/14651858.CD009379.pub3","DOI":"10.1002\/14651858.CD009379.pub3"},{"issue":"11","key":"10892_CR30","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1089\/wound.2019.0983","volume":"9","author":"N Ahuja","year":"2020","unstructured":"Ahuja, N., Jin, R., Powers, C., Billi, A., & Bass, K. (2020). Dehydrated human amnion chorion membrane as treatment for pediatric burns. Advances in Wound Care, 9(11), 602\u2013611. https:\/\/doi.org\/10.1089\/wound.2019.0983","journal-title":"Advances in Wound Care"},{"issue":"9","key":"10892_CR31","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1089\/wound.2015.0635","volume":"4","author":"RG Frykberg","year":"2015","unstructured":"Frykberg, R. G., & Banks, J. (2015). Challenges in the treatment of chronic wounds. Advances in Wound Care, 4(9), 560\u2013582. https:\/\/doi.org\/10.1089\/wound.2015.0635","journal-title":"Advances in Wound Care"},{"issue":"9","key":"10892_CR32","doi-asserted-by":"publisher","first-page":"4928","DOI":"10.3390\/ijms23094928","volume":"23","author":"P Schilrreff","year":"2022","unstructured":"Schilrreff, P., & Alexiev, U. (2022). Chronic inflammation in non-healing skin wounds and promising natural bioactive compounds treatment. International Journal of Molecular Sciences, 23(9), 4928. https:\/\/doi.org\/10.3390\/ijms23094928","journal-title":"International Journal of Molecular Sciences"},{"issue":"5","key":"10892_CR33","doi-asserted-by":"publisher","first-page":"700","DOI":"10.3390\/biom11050700","volume":"11","author":"K Raziyeva","year":"2021","unstructured":"Raziyeva, K., Kim, Y., Zharkinbekov, Z., Kassymbek, K., Jimi, S., & Saparov, A. (2021). Immunology of acute and chronic wound healing. Biomolecules, 11(5), 700. https:\/\/doi.org\/10.3390\/biom11050700","journal-title":"Biomolecules"},{"key":"10892_CR34","doi-asserted-by":"publisher","first-page":"116035","DOI":"10.1016\/j.biopha.2023.116035","volume":"170","author":"X Wang","year":"2024","unstructured":"Wang, X., Li, R., & Zhao, H. (2024). Enhancing angiogenesis: Innovative drug delivery systems to facilitate diabetic wound healing. Biomedicine & Pharmacotherapy, 170, 116035. https:\/\/doi.org\/10.1016\/j.biopha.2023.116035","journal-title":"Biomedicine & Pharmacotherapy"},{"key":"10892_CR35","doi-asserted-by":"publisher","unstructured":"Mohammed, Y. A., Farouk, H. K., Gbreel, M. I., Ali, A. M., Salah, A. A., Nourelden, A. Z., & Gawad, M. M. A. (2022). Human amniotic membrane products for patients with diabetic foot ulcers. do they help? a systematic review and meta\u2010analysis. Journal of Foot and Ankle Research, 15(1). https:\/\/doi.org\/10.1186\/s13047-022-00575-y","DOI":"10.1186\/s13047-022-00575-y"},{"issue":"1","key":"10892_CR36","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1186\/s12893-021-01084-8","volume":"21","author":"K Lakmal","year":"2021","unstructured":"Lakmal, K., Basnayake, O., & Hettiarachchi, D. (2021). Systematic review on the rational use of amniotic membrane allografts in diabetic foot ulcer treatment. BMC Surgery, 21(1), 87. https:\/\/doi.org\/10.1186\/s12893-021-01084-8","journal-title":"BMC Surgery"},{"key":"10892_CR37","doi-asserted-by":"publisher","unstructured":"Serena, T. E., Orgill, D. P., Armstrong, D. G., Galiano, R. D., Glat, P., Carter, M., \u2026 Zelen, C. M. (2022). \u201cA multicenter randomized controlled clinical trial evaluating two application regimens of dehydrated human amniotic membrane and standard of care vs standard of care alone in the treatment of venous leg ulcers. Plastic & Reconstructive Surgery. https:\/\/doi.org\/10.1097\/PRS.0000000000009650","DOI":"10.1097\/PRS.0000000000009650"},{"key":"10892_CR38","doi-asserted-by":"publisher","unstructured":"Mermet, I., Pottier, N., Sainthillier, J. M., Malugani, C., Cairey\u2010Remonnay, S., Maddens, S., \u2026 Aubin, F. (2007). Use of amniotic membrane transplantation in the treatment of venous leg ulcers. Wound Repair and Regeneration, 15(4), 459\u2013464. https:\/\/doi.org\/10.1111\/j.1524-475X.2007.00252.x","DOI":"10.1111\/j.1524-475X.2007.00252.x"},{"issue":"5","key":"10892_CR39","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1111\/j.1524-475X.2008.00410.x","volume":"16","author":"S Barrientos","year":"2008","unstructured":"Barrientos, S., Stojadinovic, O., Golinko, M. S., Brem, H., & Tomic-Canic, M. (2008). Perspective article: Growth factors and cytokines in wound healing. Wound Repair and Regeneration, 16(5), 585\u2013601. https:\/\/doi.org\/10.1111\/j.1524-475X.2008.00410.x","journal-title":"Wound Repair and Regeneration"},{"issue":"15","key":"10892_CR40","doi-asserted-by":"publisher","first-page":"3227","DOI":"10.1242\/jcs.00610","volume":"116","author":"I Haase","year":"2003","unstructured":"Haase, I., Evans, R., Pofahl, R., & Watt, F. M. (2003). Regulation of keratinocyte shape, migration and wound epithelialization by IGF-1- and EGF-dependent signalling pathways. Journal of Cell Science, 116(15), 3227\u20133238. https:\/\/doi.org\/10.1242\/jcs.00610","journal-title":"Journal of Cell Science"},{"key":"10892_CR41","doi-asserted-by":"publisher","unstructured":"Alcaraz, A., Mrowiec, A., Insausti, C. L., Garc\u00eda-Vizca\u00edno, E. M., Ruiz-Canada, C., L\u00f3pez-Mart\u00ednez, M. C., \u2026 Nicol\u00e1s, F. J. (2013). Autocrine TGF-\u03b2 Induces Epithelial to Mesenchymal Transition in Human Amniotic Epithelial Cells. Cell Transplantation, 22(8), 1351\u20131367. https:\/\/doi.org\/10.3727\/096368912X657387","DOI":"10.3727\/096368912X657387"},{"key":"10892_CR42","doi-asserted-by":"publisher","unstructured":"Alcaraz, A., Mrowiec, A., Insausti, C. L., Bernab\u00e9-Garc\u00eda, \u00c1., Garc\u00eda-Vizca\u00edno, E. M., L\u00f3pez-Mart\u00ednez, M. C., \u2026 Nicol\u00e1s, F. J. (2015). Amniotic membrane modifies the genetic program induced by TGF\u00df, stimulating keratinocyte proliferation and migration in chronic wounds. PLOS ONE, 10(8), e0135324. https:\/\/doi.org\/10.1371\/journal.pone.0135324","DOI":"10.1371\/journal.pone.0135324"},{"key":"10892_CR43","doi-asserted-by":"publisher","unstructured":"Insausti, C. L., Alcaraz, A., Garc\u00eda\u2010Vizca\u00edno, E. M., Mrowiec, A., L\u00f3pez\u2010Mart\u00ednez, M. C., Blanquer, M., \u2026 Nicol\u00e1s, F. J. (2010). Amniotic membrane induces epithelialization in massive posttraumatic wounds. Wound Repair and Regeneration, 18(4), 368\u2013377. https:\/\/doi.org\/10.1111\/j.1524-475X.2010.00604.x","DOI":"10.1111\/j.1524-475X.2010.00604.x"},{"key":"10892_CR44","doi-asserted-by":"publisher","unstructured":"Li, G., Gustafson-Brown, C., Hanks, S. K., Nason, K., Arbeit, J. M., Pogliano, K., \u2026 Johnson, R. S. (2003). c-Jun is essential for organization of the epidermal leading edge. Developmental Cell, 4(6), 865\u2013877. https:\/\/doi.org\/10.1016\/S1534-5807(03)00159-X","DOI":"10.1016\/S1534-5807(03)00159-X"},{"key":"10892_CR45","doi-asserted-by":"publisher","unstructured":"Wu, M., Yu, Z., Matar, D. Y., Karvar, M., Chen, Z., Ng, B., \u2026 Panayi, A. C. (2023). Human amniotic membrane promotes angiogenesis in an oxidative stress chronic diabetic murine wound model. Advances in Wound Care, 12(6), 301\u2013315. https:\/\/doi.org\/10.1089\/wound.2022.0005","DOI":"10.1089\/wound.2022.0005"},{"key":"10892_CR46","doi-asserted-by":"publisher","unstructured":"Farzan, R., Moeinian, M., Abdollahi, A., Jahangard-Rafsanjani, Z., Alipour, A., Ebrahimi, M., & Khorasani, G. (2018). Effects of amniotic membrane extract and deferoxamine on angiogenesis in wound healing: an in vivo model. Journal of Wound Care, 27(Sup6), S26\u2013S32. https:\/\/doi.org\/10.12968\/jowc.2018.27.Sup6.S26","DOI":"10.12968\/jowc.2018.27.Sup6.S26"},{"issue":"5","key":"10892_CR47","doi-asserted-by":"publisher","first-page":"2593","DOI":"10.1073\/pnas.031252398","volume":"98","author":"V Stellmach","year":"2001","unstructured":"Stellmach, V., Crawford, S. E., Zhou, W., & Bouck, N. (2001). Prevention of ischemia-induced retinopathy by the natural ocular antiangiogenic agent pigment epithelium-derived factor. Proceedings of the National Academy of Sciences of the United States of America, 98(5), 2593\u20132597. https:\/\/doi.org\/10.1073\/pnas.031252398","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"6","key":"10892_CR48","doi-asserted-by":"publisher","first-page":"1758","DOI":"10.1167\/iovs.03-0882","volume":"45","author":"C Shao","year":"2004","unstructured":"Shao, C., Sima, J., Zhang, S. X., Jin, J., Reinach, P., Wang, Z., & Ma, J. (2004). Suppression of corneal neovascularization by PEDF release from human amniotic membranes. Investigative ophthalmology & visual science, 45(6), 1758\u20131762. https:\/\/doi.org\/10.1167\/iovs.03-0882","journal-title":"Investigative ophthalmology & visual science"},{"issue":"3","key":"10892_CR49","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1097\/00003226-200005000-00018","volume":"19","author":"Y Hao","year":"2000","unstructured":"Hao, Y., Ma, D. H., Hwang, D. G., Kim, W. S., & Zhang, F. (2000). Identification of antiangiogenic and antiinflammatory proteins in human amniotic membrane. Cornea, 19(3), 348\u2013352. https:\/\/doi.org\/10.1097\/00003226-200005000-00018","journal-title":"Cornea"},{"issue":"3","key":"10892_CR50","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1006\/exer.1999.0794","volume":"70","author":"JS Kim","year":"2000","unstructured":"Kim, J. S., Kim, J. C., Na, B. K., Jeong, J. M., & Song, C. Y. (2000). Amniotic membrane patching promotes healing and inhibits proteinase activity on wound healing following acute corneal alkali burn. Experimental Eye Research, 70(3), 329\u2013337. https:\/\/doi.org\/10.1006\/exer.1999.0794","journal-title":"Experimental Eye Research"},{"key":"10892_CR51","doi-asserted-by":"publisher","unstructured":"Ramuta, T. \u017d., \u0160ket, T., Star\u010di\u010d Erjavec, M., & Kreft, M. E. (2021). Antimicrobial activity of human fetal membranes: From biological function to clinical use. Frontiers in Bioengineering and Biotechnology, 9. https:\/\/doi.org\/10.3389\/fbioe.2021.691522","DOI":"10.3389\/fbioe.2021.691522"},{"key":"10892_CR52","doi-asserted-by":"publisher","unstructured":"Ramirez-Acu\u00f1a, J. M., Cardenas-Cadena, S. A., Marquez-Salas, P. A., Garza-Veloz, I., Perez-Favila, A., Cid-Baez, M. A., \u2026 Martinez-Fierro, M. L. (2019). Diabetic foot ulcers: Current advances in antimicrobial therapies and emerging treatments. Antibiotics, 8(4), 193. https:\/\/doi.org\/10.3390\/antibiotics8040193","DOI":"10.3390\/antibiotics8040193"},{"key":"10892_CR53","doi-asserted-by":"publisher","unstructured":"Tanideh, N., Keshavarzi, F., Hemat Zadeh, A., Daneshi, S., Koohi-Hosseinabadi, O., Mokhtari, M., \u2026 Asadi-Yousefabad, S.-L. (2020). Healing effects of human amniotic membrane and burned wool on the second-degree burn in rats. Galen Medical Journal, 9, e1759. https:\/\/doi.org\/10.31661\/gmj.v9i0.1759","DOI":"10.31661\/gmj.v9i0.1759"},{"key":"10892_CR54","doi-asserted-by":"publisher","unstructured":"Momeni, M., Zarehaghighi, M., Hajimiri, M., Khorasani, G., Dinarvand, R., Nekookar, A., \u2026 Ebrahimi, M. (2018). In vitro and in vivo investigation of a novel amniotic\u2010based chitosan dressing for wound healing. Wound Repair and Regeneration, 26(1), 87\u2013101. https:\/\/doi.org\/10.1111\/wrr.12618","DOI":"10.1111\/wrr.12618"},{"issue":"Suppl 1","key":"10892_CR55","doi-asserted-by":"publisher","first-page":"92","DOI":"10.6002\/ect.MESOT2018.O29","volume":"17","author":"Z Kakabadze","year":"2019","unstructured":"Kakabadze, Z., Chakhunashvili, D., Gogilashvili, K., Ediberidze, K., Chakhunashvili, K., Kalandarishvili, K., & Karalashvili, L. (2019). Bone marrow stem cell and decellularized human amniotic membrane for the treatment of nonhealing wound after radiation therapy. Experimental and Clinical Transplantation, 17(Suppl 1), 92\u201398. https:\/\/doi.org\/10.6002\/ect.MESOT2018.O29","journal-title":"Experimental and Clinical Transplantation"},{"issue":"S2","key":"10892_CR56","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1007\/s12262-013-0864-x","volume":"77","author":"SH Salehi","year":"2015","unstructured":"Salehi, S. H., As\u2019adi, K., Mousavi, S. J., & Shoar, S. (2015). Evaluation of amniotic membrane effectiveness in skin graft donor site dressing in burn patients. Indian Journal of Surgery, 77(S2), 427\u2013431. https:\/\/doi.org\/10.1007\/s12262-013-0864-x","journal-title":"Indian Journal of Surgery"},{"key":"10892_CR57","doi-asserted-by":"publisher","unstructured":"de Nicodemo, M. C., das Neves, L. R., Aguiar, J. C., de Brito, F. S., Ferreira, I., Sant\u2019Anna, L. B., \u2026 Arisawa, E. A. L. S. (2017). Amniotic membrane as an option for treatment of acute Achilles tendon injury in rats. Acta Cirurgica Brasileira, 32(2), 125\u2013139. https:\/\/doi.org\/10.1590\/s0102-865020170205","DOI":"10.1590\/s0102-865020170205"},{"key":"10892_CR58","doi-asserted-by":"publisher","unstructured":"de Girolamo, L., Morlin Ambra, L. F., Perucca Orfei, C., McQuilling, J. P., Kimmerling, K. A., Mowry, K. C., \u2026 Gomoll, A. H. (2019). Treatment with human amniotic suspension allograft improves tendon healing in a rat model of collagenase-induced tendinopathy. Cells, 8(11), 1411. https:\/\/doi.org\/10.3390\/cells8111411","DOI":"10.3390\/cells8111411"},{"key":"10892_CR59","doi-asserted-by":"publisher","unstructured":"L\u00f3pez Mart\u00ednez, J. A., Rodr\u00edguez Valiente, M., Fuente\u2010Mora, C., Garc\u00eda\u2010Hern\u00e1ndez, A. M., C\u00e1novas Sanch\u00eds, S., & Fern\u00e1ndez Pascual, C. J. (2021). Use of cryopreserved human amniotic membrane in the treatment of skin ulcers secondary to calciphylaxis. Dermatologic Therapy, 34(2). https:\/\/doi.org\/10.1111\/dth.14769","DOI":"10.1111\/dth.14769"},{"key":"10892_CR60","doi-asserted-by":"publisher","unstructured":"Qin, L., Zhang, J., Xiao, Y., Liu, K., Cui, Y., Xu, F., \u2026 Wang, N. (2022). A novel long-term intravenous combined with local treatment with human amnion-derived mesenchymal stem cells for a multidisciplinary rescued uremic calciphylaxis patient and the underlying mechanism. Journal of Molecular Cell Biology, 14(2). https:\/\/doi.org\/10.1093\/jmcb\/mjac010","DOI":"10.1093\/jmcb\/mjac010"},{"key":"10892_CR61","doi-asserted-by":"publisher","unstructured":"Castiglia, D., Fortugno, P., Condorelli, A. G., Barresi, S., De Luca, N., Pizzi, S., \u2026 Tartaglia, M. (2021). A novel phenotype of junctional epidermolysis bullosa with transient skin fragility and predominant ocular involvement responsive to human amniotic membrane eyedrops. Genes, 12(5), 716. https:\/\/doi.org\/10.3390\/genes12050716","DOI":"10.3390\/genes12050716"},{"key":"10892_CR62","doi-asserted-by":"publisher","unstructured":"Glat, P., Orgill, D. P., Galiano, R., Armstrong, D., Serena, T., DiDomenico, L. A., \u2026 Zelen, C. M. (2019). Placental membrane provides improved healing efficacy and lower cost versus a tissue-engineered human skin in the treatment of diabetic foot ulcerations. Plastic and Reconstructive Surgery - Global Open, 7(8), e2371. https:\/\/doi.org\/10.1097\/GOX.0000000000002371","DOI":"10.1097\/GOX.0000000000002371"},{"issue":"3","key":"10892_CR63","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1007\/s13770-013-0004-5","volume":"10","author":"R Singh","year":"2013","unstructured":"Singh, R., Kumar, A., Singh, D., & Malviya, A. (2013). Use of gamma-irradiated amniotic membrane for the healing of split skin graft donor site. Tissue Engineering and Regenerative Medicine, 10(3), 110\u2013114. https:\/\/doi.org\/10.1007\/s13770-013-0004-5","journal-title":"Tissue Engineering and Regenerative Medicine"},{"key":"10892_CR64","doi-asserted-by":"publisher","unstructured":"Chehelcheraghi, F., Abbaszadeh, A., & Tavafi, M. (2018). Skin mast cell promotion in random skin flaps in rats using bone marrow mesenchymal stem cells and amniotic membrane. Iranian Biomedical Journal, 22(5), 322\u2013330. https:\/\/doi.org\/10.29252\/ibj.22.5.322","DOI":"10.29252\/ibj.22.5.322"},{"issue":"12","key":"10892_CR65","doi-asserted-by":"publisher","first-page":"1700","DOI":"10.1016\/j.bjps.2012.06.013","volume":"65","author":"\u00d6 \u00d6zkaya","year":"2012","unstructured":"\u00d6zkaya, \u00d6., Egemen, O., Ye\u015filada, A., Sak\u0131z, D., & Ugurlu, K. (2012). The effect of nonpreserved human amniotic membrane on the survival of ischaemic skin flaps in rats. Journal of Plastic, Reconstructive & Aesthetic Surgery, 65(12), 1700\u20131705. https:\/\/doi.org\/10.1016\/j.bjps.2012.06.013","journal-title":"Journal of Plastic, Reconstructive & Aesthetic Surgery"},{"key":"10892_CR66","doi-asserted-by":"publisher","unstructured":"Campelo, M. B. D., Santos, J. de A. F., Maia Filho, A. L. M., Ferreira, D. C. L., Sant\u2019Anna, L. B., Oliveira, R. A. de, \u2026 Arisawa, E. \u00c2. L. (2018). Effects of the application of the amniotic membrane in the healing process of skin wounds in rats. Acta Cirurgica Brasileira, 33(2), 144\u2013155. https:\/\/doi.org\/10.1590\/s0102-865020180020000006","DOI":"10.1590\/s0102-865020180020000006"},{"key":"10892_CR67","doi-asserted-by":"publisher","unstructured":"Murphy, S. V., Skardal, A., Nelson, R. A., Sunnon, K., Reid, T., Clouse, C., \u2026 Atala, A. (2020). Amnion membrane hydrogel and amnion membrane powder accelerate wound healing in a full thickness porcine skin wound model. Stem Cells Translational Medicine, 9(1), 80\u201392. https:\/\/doi.org\/10.1002\/sctm.19-0101","DOI":"10.1002\/sctm.19-0101"},{"issue":"01","key":"10892_CR68","doi-asserted-by":"publisher","first-page":"11","DOI":"10.5999\/aps.2013.40.1.11","volume":"40","author":"H Kim","year":"2013","unstructured":"Kim, H., Son, D., Choi, T. H., Jung, S., Kwon, S., Kim, J., & Han, K. (2013). Evaluation of an amniotic membrane-collagen dermal substitute in the management of full-thickness skin defects in a pig. Archives of Plastic Surgery, 40(01), 11\u201318. https:\/\/doi.org\/10.5999\/aps.2013.40.1.11","journal-title":"Archives of Plastic Surgery"},{"key":"10892_CR69","doi-asserted-by":"publisher","unstructured":"Zhou, H., Wang, L., Zhang, C., Hu, J., Chen, J., Du, W., \u2026 Quan, R. (2019). Feasibility of repairing full-thickness skin defects by iPSC-derived epithelial stem cells seeded on a human acellular amniotic membrane. Stem Cell Research & Therapy, 10(1), 155. https:\/\/doi.org\/10.1186\/s13287-019-1234-9","DOI":"10.1186\/s13287-019-1234-9"},{"key":"10892_CR70","doi-asserted-by":"publisher","unstructured":"Xue, S.-L., Liu, K., Parolini, O., Wang, Y., Deng, L., & Huang, Y.-C. (2018). Human acellular amniotic membrane implantation for lower third nasal reconstruction: a promising therapy to promote wound healing. Burns & Trauma, 6. https:\/\/doi.org\/10.1186\/s41038-018-0136-x","DOI":"10.1186\/s41038-018-0136-x"},{"key":"10892_CR71","doi-asserted-by":"publisher","unstructured":"Farzamfar, S., Salehi, M., Ehterami, A., Naseri-Nosar, M., Vaez, A., Zarnani, A. H., \u2026 Aleahmad, M. (2018). Promotion of excisional wound repair by a menstrual blood-derived stem cell-seeded decellularized human amniotic membrane. Biomedical Engineering Letters, 8(4), 393\u2013398. https:\/\/doi.org\/10.1007\/s13534-018-0084-1","DOI":"10.1007\/s13534-018-0084-1"},{"key":"10892_CR72","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2014\/698256","volume":"2014","author":"D Grinsell","year":"2014","unstructured":"Grinsell, D., & Keating, C. P. (2014). Peripheral nerve reconstruction after injury: A review of clinical and experimental therapies. BioMed Research International, 2014, 1\u201313. https:\/\/doi.org\/10.1155\/2014\/698256","journal-title":"BioMed Research International"},{"key":"10892_CR73","doi-asserted-by":"publisher","unstructured":"Wan, T., Li, Q.-C., Qin, M.-Y., Wang, Y.-L., Zhang, F.-S., Zhang, X.-M., \u2026 Zhang, P.-X. (2024). Strategies for treating traumatic neuromas with tissue-engineered materials. Biomolecules, 14(4), 484. https:\/\/doi.org\/10.3390\/biom14040484","DOI":"10.3390\/biom14040484"},{"issue":"9","key":"10892_CR74","first-page":"612","volume":"19","author":"SH Sadraie","year":"2016","unstructured":"Sadraie, S. H., Parivar, K., Arabi, F., Moattari, M., Kaka, G., & Mansouri, K. (2016). Study of transected sciatic nerve repair by amniotic membrane with betamethasone in adult albino wistar rats. Archives of Iranian Medicine, 19(9), 612\u2013617.","journal-title":"Archives of Iranian Medicine"},{"issue":"2","key":"10892_CR75","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1055\/s-2004-820772","volume":"20","author":"GY \u00d6zgenel","year":"2004","unstructured":"\u00d6zgenel, G. Y., & F\u00edl\u00edz, G. (2004). Combined application of human amniotic membrane wrapping and hyaluronic acid injection in epineurectomized rat sciatic nerve. Journal of Reconstructive Microsurgery, 20(2), 153\u2013157. https:\/\/doi.org\/10.1055\/s-2004-820772","journal-title":"Journal of Reconstructive Microsurgery"},{"key":"10892_CR76","doi-asserted-by":"publisher","unstructured":"Zhang, Z.-Y., Yang, J., Fan, Z.-H., Wang, D.-L., Wang, Y.-Y., Zhang, T., \u2026 Yu, C.-Y. (2019). Fresh human amniotic membrane effectively promotes the repair of injured common peroneal nerve. Neural Regeneration Research, 14(12), 2199. https:\/\/doi.org\/10.4103\/1673-5374.262596","DOI":"10.4103\/1673-5374.262596"},{"key":"10892_CR77","doi-asserted-by":"publisher","unstructured":"Ali, O. A., & Mooney, D. J. (2007). Converging Cell Therapy with Biomaterials. In Cellular Transplantation (pp. 591\u2013609). Elsevier. https:\/\/doi.org\/10.1016\/B978-012369415-7\/50032-6","DOI":"10.1016\/B978-012369415-7\/50032-6"},{"key":"10892_CR78","doi-asserted-by":"publisher","unstructured":"Akram, R., Anwar, H., Javed, M. S., Rasul, A., Imran, A., Malik, S. A., \u2026 Hussain, G. (2022). Axonal regeneration: Underlying molecular mechanisms and potential therapeutic targets. Biomedicines, 10(12), 3186. https:\/\/doi.org\/10.3390\/biomedicines10123186","DOI":"10.3390\/biomedicines10123186"},{"key":"10892_CR79","doi-asserted-by":"publisher","first-page":"e281","DOI":"10.1016\/j.wneu.2019.02.042","volume":"126","author":"B Tarabay","year":"2019","unstructured":"Tarabay, B., Abdallah, Y., Kobaiter-Maarrawi, S., Yammine, P., & Maarrawi, J. (2019). Outcome and prognosis of microsurgical decompression in idiopathic severe common fibular nerve entrapment: Prospective clinical study. World Neurosurgery, 126, e281\u2013e287. https:\/\/doi.org\/10.1016\/j.wneu.2019.02.042","journal-title":"World Neurosurgery"},{"issue":"1","key":"10892_CR80","doi-asserted-by":"publisher","first-page":"32","DOI":"10.14444\/8380","volume":"17","author":"ML Moore","year":"2023","unstructured":"Moore, M. L., Deckey, D. G., Pollock, J. R., Smith, J.-R.H., Tokish, J. M., & Neal, M. T. (2023). The Effect of Amniotic Tissue on Spinal Interventions: A Systematic Review. International Journal of Spine Surgery, 17(1), 32\u201342. https:\/\/doi.org\/10.14444\/8380","journal-title":"International Journal of Spine Surgery"},{"key":"10892_CR81","doi-asserted-by":"publisher","unstructured":"Wang, T., Xu, J., Zhu, A., Lu, H., Miao, Z., Zhao, P., \u2026 Wu, W. (2016). Human amniotic epithelial cells combined with silk fibroin scaffold in the repair of spinal cord injury. Neural Regeneration Research, 11(10), 1670. https:\/\/doi.org\/10.4103\/1673-5374.193249","DOI":"10.4103\/1673-5374.193249"},{"issue":"10","key":"10892_CR82","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1242\/dmm.025833","volume":"9","author":"J Kjell","year":"2016","unstructured":"Kjell, J., & Olson, L. (2016). Rat models of spinal cord injury: From pathology to potential therapies. Disease Models & Mechanisms, 9(10), 1125\u20131137. https:\/\/doi.org\/10.1242\/dmm.025833","journal-title":"Disease Models & Mechanisms"},{"key":"10892_CR83","doi-asserted-by":"publisher","first-page":"505","DOI":"10.25259\/SNI_794_2022","volume":"13","author":"Z Shah","year":"2022","unstructured":"Shah, Z., Bakhshi, S. K., Bajwa, M. H., Khalil, M., Dewan, M. C., & Shamim, S. M. (2022). Human amniotic membrane as a dural substitute in neurosurgery: A systematic review. Surgical Neurology International, 13, 505. https:\/\/doi.org\/10.25259\/SNI_794_2022","journal-title":"Surgical Neurology International"},{"issue":"6","key":"10892_CR84","doi-asserted-by":"publisher","first-page":"323","DOI":"10.3340\/jkns.2011.49.6.323","volume":"49","author":"HJ Choi","year":"2011","unstructured":"Choi, H. J., Kim, K. B., & Kwon, Y.-M. (2011). Effect of amniotic membrane to reduce postlaminectomy epidural adhesion on a rat model. Journal of Korean Neurosurgical Society, 49(6), 323. https:\/\/doi.org\/10.3340\/jkns.2011.49.6.323","journal-title":"Journal of Korean Neurosurgical Society"},{"issue":"05","key":"10892_CR85","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1055\/s-0032-1321506","volume":"73","author":"T Tomita","year":"2012","unstructured":"Tomita, T., Hayashi, N., Okabe, M., Yoshida, T., Hamada, H., Endo, S., & Nikaido, T. (2012). New dried human amniotic membrane is useful as a substitute for dural repair after skull base surgery. Journal of Neurological Surgery Part B: Skull Base, 73(05), 302\u2013307. https:\/\/doi.org\/10.1055\/s-0032-1321506","journal-title":"Journal of Neurological Surgery Part B: Skull Base"},{"issue":"05","key":"10892_CR86","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1055\/s-0036-1584229","volume":"77","author":"C Le","year":"2016","unstructured":"Le, C., Strong, E., & Luu, Q. (2016). Management of anterior skull base cerebrospinal fluid leaks. Journal of Neurological Surgery Part B: Skull Base, 77(05), 404\u2013411. https:\/\/doi.org\/10.1055\/s-0036-1584229","journal-title":"Journal of Neurological Surgery Part B: Skull Base"},{"key":"10892_CR87","doi-asserted-by":"publisher","DOI":"10.3238\/arztebl.2011.0243","author":"D Meller","year":"2011","unstructured":"Meller, D., Pauklin, M., Thomasen, H., Westekemper, H., & Steuhl, K.-P. (2011). Amniotic membrane transplantation in the human eye. Deutsches \u00c4rzteblatt international. https:\/\/doi.org\/10.3238\/arztebl.2011.0243","journal-title":"Deutsches \u00c4rzteblatt international"},{"key":"10892_CR88","doi-asserted-by":"publisher","unstructured":"Tseng, S. C. G. (2016). HC-HA\/PTX3 Purified from amniotic membrane as novel regenerative matrix: Insight into relationship between inflammation and regeneration. Investigative Opthalmology & Visual Science, 57(5), ORSFh1. https:\/\/doi.org\/10.1167\/iovs.15-17637","DOI":"10.1167\/iovs.15-17637"},{"key":"10892_CR89","doi-asserted-by":"publisher","unstructured":"Ogawa, Y., He, H., Mukai, S., Imada, T., Nakamura, S., Su, C.-W., \u2026 Tsubota, K. (2017). Heavy chain-hyaluronan\/pentraxin 3 from amniotic membrane suppresses inflammation and scarring in murine lacrimal gland and conjunctiva of chronic graft-versus-host disease. Scientific Reports, 7(1), 42195. https:\/\/doi.org\/10.1038\/srep42195","DOI":"10.1038\/srep42195"},{"key":"10892_CR90","doi-asserted-by":"publisher","unstructured":"Linhares, A. C. B., Martinelli, A. C., Ghem, M. R. D., Dias, P. B., & Wasilewski, D. (2024). Amniotic membrane transplantation for neurotrophic corneal ulcers. Arquivos Brasileiros de Oftalmologia, 87(2). https:\/\/doi.org\/10.5935\/0004-2749.2023-2022-0341","DOI":"10.5935\/0004-2749.2023-2022-0341"},{"issue":"10","key":"10892_CR91","doi-asserted-by":"publisher","first-page":"1733","DOI":"10.3390\/medicina59101733","volume":"59","author":"Y He","year":"2023","unstructured":"He, Y., Wong, H., Gu, J., & Lin, L. (2023). Corneal descemetocele management with multi-layer amniotic membrane transplantation in an ocular graft-versus-host disease case. Medicina, 59(10), 1733. https:\/\/doi.org\/10.3390\/medicina59101733","journal-title":"Medicina"},{"issue":"3","key":"10892_CR92","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1016\/S0161-6420(00)00567-4","volume":"108","author":"A Solomon","year":"2001","unstructured":"Solomon, A., Pires, R. T. F., & Tseng, S. C. G. (2001). Amniotic membrane transplantation after extensive removal of primary and recurrent pterygia. Ophthalmology, 108(3), 449\u2013460. https:\/\/doi.org\/10.1016\/S0161-6420(00)00567-4","journal-title":"Ophthalmology"},{"issue":"1","key":"10892_CR93","first-page":"23","volume":"3","author":"A Katbaab","year":"2008","unstructured":"Katbaab, A., Anvari Ardekani, H.-R., Khoshniyat, H., & Jahadi Hosseini, H.-R. (2008). Amniotic membrane transplantation for primary pterygium surgery. Journal of Ophthalmic & Vision Research, 3(1), 23\u201327.","journal-title":"Journal of Ophthalmic & Vision Research"},{"issue":"5","key":"10892_CR94","doi-asserted-by":"publisher","first-page":"552","DOI":"10.5301\/EJO.2010.6192","volume":"21","author":"RS Asoklis","year":"2011","unstructured":"Asoklis, R. S., Damijonaityte, A., Butkiene, L., Makselis, A., Petroska, D., Pajaujis, M., & Juodkaite, G. (2011). Ocular surface reconstruction using amniotic membrane following excision of conjunctival and limbal tumors. European Journal of Ophthalmology, 21(5), 552\u2013558. https:\/\/doi.org\/10.5301\/EJO.2010.6192","journal-title":"European Journal of Ophthalmology"},{"issue":"5","key":"10892_CR95","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1136\/bjo.85.5.567","volume":"85","author":"DF Anderson","year":"2001","unstructured":"Anderson, D. F. (2001). Amniotic membrane transplantation for partial limbal stem cell deficiency. British Journal of Ophthalmology, 85(5), 567\u2013575. https:\/\/doi.org\/10.1136\/bjo.85.5.567","journal-title":"British Journal of Ophthalmology"},{"issue":"4","key":"10892_CR96","first-page":"281","volume":"52","author":"VS Sangwan","year":"2004","unstructured":"Sangwan, V. S., Matalia, H. P., Vemuganti, G. K., & Rao, G. N. (2004). Amniotic membrane transplantation for reconstruction of corneal epithelial surface in cases of partial limbal stem cell deficiency. Indian journal of ophthalmology, 52(4), 281\u2013285.","journal-title":"Indian journal of ophthalmology"},{"issue":"7","key":"10892_CR97","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1136\/bjophthalmol-2011-301164","volume":"96","author":"VS Sangwan","year":"2012","unstructured":"Sangwan, V. S., Basu, S., MacNeil, S., & Balasubramanian, D. (2012). Simple limbal epithelial transplantation (SLET): A novel surgical technique for the treatment of unilateral limbal stem cell deficiency. British Journal of Ophthalmology, 96(7), 931\u2013934. https:\/\/doi.org\/10.1136\/bjophthalmol-2011-301164","journal-title":"British Journal of Ophthalmology"},{"issue":"6","key":"10892_CR98","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1016\/j.jaapos.2010.09.017","volume":"14","author":"RR Kassem","year":"2010","unstructured":"Kassem, R. R., Gawdat, G. I., & Zedan, R. H. (2010). Severe fibrosis of extraocular muscles after the use of lyophilized amniotic membrane in strabismus surgery. Journal of American Association for Pediatric Ophthalmology and Strabismus, 14(6), 548\u2013549. https:\/\/doi.org\/10.1016\/j.jaapos.2010.09.017","journal-title":"Journal of American Association for Pediatric Ophthalmology and Strabismus"},{"issue":"2","key":"10892_CR99","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1007\/s10384-012-0217-5","volume":"57","author":"B Tugcu","year":"2013","unstructured":"Tugcu, B., Helvacioglu, F., Yuzbasioglu, E., Gurez, C., & Yigit, U. (2013). Amniotic membrane in the management of strabismus reoperations. Japanese Journal of Ophthalmology, 57(2), 239\u2013244. https:\/\/doi.org\/10.1007\/s10384-012-0217-5","journal-title":"Japanese Journal of Ophthalmology"},{"issue":"2","key":"10892_CR100","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/S0002-9394(01)00930-8","volume":"132","author":"M Yamada","year":"2001","unstructured":"Yamada, M., Shinoda, K., Hatakeyama, A., Nishina, S., & Mashima, Y. (2001). Fat adherence syndrome after retinal surgery treated with amniotic membrane transplantation. American Journal of Ophthalmology, 132(2), 280\u2013282. https:\/\/doi.org\/10.1016\/S0002-9394(01)00930-8","journal-title":"American Journal of Ophthalmology"},{"issue":"1","key":"10892_CR101","doi-asserted-by":"publisher","first-page":"18264","DOI":"10.1038\/s41598-020-75292-2","volume":"10","author":"T Caporossi","year":"2020","unstructured":"Caporossi, T., Pacini, B., Bacherini, D., Barca, F., Faraldi, F., & Rizzo, S. (2020). Human amniotic membrane plug to promote failed macular hole closure. Scientific Reports, 10(1), 18264. https:\/\/doi.org\/10.1038\/s41598-020-75292-2","journal-title":"Scientific Reports"},{"key":"10892_CR102","doi-asserted-by":"publisher","first-page":"102267","DOI":"10.1016\/j.ajoc.2025.102267","volume":"37","author":"MH Yamamoto","year":"2025","unstructured":"Yamamoto, M. H., Marin, A. I., & Tsui, I. (2025). Management of traumatic macular hole and retinal detachment using amniotic membrane transplantation: A case report. American Journal of Ophthalmology Case Reports, 37, 102267. https:\/\/doi.org\/10.1016\/j.ajoc.2025.102267","journal-title":"American Journal of Ophthalmology Case Reports"},{"issue":"19","key":"10892_CR103","doi-asserted-by":"publisher","first-page":"6222","DOI":"10.3390\/jcm12196222","volume":"12","author":"H-I Chiu","year":"2023","unstructured":"Chiu, H.-I., & Tsai, C.-C. (2023). Self-retained, sutureless amniotic membrane transplantation for the management of ocular surface diseases. Journal of Clinical Medicine, 12(19), 6222. https:\/\/doi.org\/10.3390\/jcm12196222","journal-title":"Journal of Clinical Medicine"},{"key":"10892_CR104","doi-asserted-by":"publisher","unstructured":"Hayek, G., Francois, J., & Perone, J.-M. (2023). Corneal perforation repair using a novel lyophilized amniotic membrane graft technique: Plug and patch. American Journal of Case Reports, 24. https:\/\/doi.org\/10.12659\/AJCR.939626","DOI":"10.12659\/AJCR.939626"},{"issue":"12","key":"10892_CR105","doi-asserted-by":"publisher","first-page":"e22693","DOI":"10.1016\/j.heliyon.2023.e22693","volume":"9","author":"Y-L Du","year":"2023","unstructured":"Du, Y.-L., Wang, J.-S., Geng, W., Duan, C.-Y., Wang, X.-H., Xie, H.-T., & Zhang, M.-C. (2023). Amniotic membrane transplantation combined with conjunctival flap covering surgery for the treatment of corneal perforations in fungal keratitis. Heliyon, 9(12), e22693. https:\/\/doi.org\/10.1016\/j.heliyon.2023.e22693","journal-title":"Heliyon"},{"issue":"8","key":"10892_CR106","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1136\/bjo.84.8.826","volume":"84","author":"H-J Chen","year":"2000","unstructured":"Chen, H.-J. (2000). Amniotic membrane transplantation for severe neurotrophic corneal ulcers. British Journal of Ophthalmology, 84(8), 826\u2013833. https:\/\/doi.org\/10.1136\/bjo.84.8.826","journal-title":"British Journal of Ophthalmology"},{"issue":"7","key":"10892_CR107","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1097\/00003226-200110000-00010","volume":"20","author":"J-S Kim","year":"2001","unstructured":"Kim, J.-S., Kim, J.-C., Hahn, T.-W., & Park, W.-C. (2001). Amniotic membrane transplantation in infectious corneal ulcer. Cornea, 20(7), 720\u2013726. https:\/\/doi.org\/10.1097\/00003226-200110000-00010","journal-title":"Cornea"},{"issue":"4","key":"10892_CR108","doi-asserted-by":"publisher","first-page":"611","DOI":"10.3346\/jkms.2004.19.4.611","volume":"19","author":"YS Kwon","year":"2004","unstructured":"Kwon, Y. S., Song, Y. S., & Kim, J. C. (2004). New treatment for band keratopathy: Superficial lamellar keratectomy, EDTA chelation and amniotic membrane transplantation. Journal of Korean Medical Science, 19(4), 611. https:\/\/doi.org\/10.3346\/jkms.2004.19.4.611","journal-title":"Journal of Korean Medical Science"},{"issue":"4","key":"10892_CR109","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1097\/00003226-200105000-00004","volume":"20","author":"DF Anderson","year":"2001","unstructured":"Anderson, D. F., Prabhasawat, P., Alfonso, E., & Tseng, S. C. G. (2001). Amniotic membrane transplantation after the primary surgical management of band keratopathy. Cornea, 20(4), 354\u2013361. https:\/\/doi.org\/10.1097\/00003226-200105000-00004","journal-title":"Cornea"},{"issue":"4","key":"10892_CR110","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1097\/00003226-200305000-00002","volume":"22","author":"JH Oh","year":"2003","unstructured":"Oh, J. H., & Kim, J. C. (2003). Repair of scleromalacia using preserved scleral graft with amniotic membrane transplantation. Cornea, 22(4), 288\u2013293. https:\/\/doi.org\/10.1097\/00003226-200305000-00002","journal-title":"Cornea"},{"issue":"3","key":"10892_CR111","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1097\/00003226-200204000-00008","volume":"21","author":"DH-K Ma","year":"2002","unstructured":"Ma, D.H.-K., Wang, S.-F., Su, W.-Y., & Tsai, R.J.-F. (2002). Amniotic membrane graft for the management of scleral melting and corneal perforation in recalcitrant infectious scleral and corneoscleral ulcers. Cornea, 21(3), 275\u2013283. https:\/\/doi.org\/10.1097\/00003226-200204000-00008","journal-title":"Cornea"},{"issue":"4","key":"10892_CR112","doi-asserted-by":"publisher","first-page":"419","DOI":"10.4103\/0974-9233.102765","volume":"19","author":"S Thatte","year":"2012","unstructured":"Thatte, S., & Gupta, L. (2012). Amniotic membrane transplantation in surgically induced necrotizing scleritis with peripheral ulcerative keratitis. Middle East African Journal of Ophthalmology, 19(4), 419. https:\/\/doi.org\/10.4103\/0974-9233.102765","journal-title":"Middle East African Journal of Ophthalmology"},{"issue":"6","key":"10892_CR113","doi-asserted-by":"publisher","first-page":"485","DOI":"10.3928\/1542-8877-19990601-14","volume":"30","author":"MT Rodr\u00edguez-Ares","year":"1999","unstructured":"Rodr\u00edguez-Ares, M. T., Touri\u00f1o, R., Capeans, C., & S\u00e1nchez-Salorio, M. (1999). Repair of scleral perforation with preserved scleral and amniotic membrane in Marfan\u2019s syndrome. Ophthalmic Surgery and Lasers, 30(6), 485\u2013487.","journal-title":"Ophthalmic Surgery and Lasers"},{"issue":"10","key":"10892_CR114","doi-asserted-by":"publisher","first-page":"1435","DOI":"10.1001\/archopht.124.10.1435","volume":"124","author":"R Goyal","year":"2006","unstructured":"Goyal, R. (2006). Amniotic membrane transplantation in children with symblepharon and massive pannus. Archives of Ophthalmology, 124(10), 1435. https:\/\/doi.org\/10.1001\/archopht.124.10.1435","journal-title":"Archives of Ophthalmology"},{"issue":"6","key":"10892_CR115","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1097\/00003226-200011000-00008","volume":"19","author":"D Meller","year":"2000","unstructured":"Meller, D., Maskin, S. L., Pires, R. T. F., & Tseng, S. C. G. (2000). Amniotic membrane transplantation for symptomatic conjunctivochalasis refractory to medical treatments. Cornea, 19(6), 796\u2013803. https:\/\/doi.org\/10.1097\/00003226-200011000-00008","journal-title":"Cornea"},{"issue":"2","key":"10892_CR116","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1016\/j.ajo.2007.03.044","volume":"144","author":"A Kheirkhah","year":"2007","unstructured":"Kheirkhah, A., Casas, V., Blanco, G., Li, W., Hayashida, Y., Chen, Y.-T., & Tseng, S. C. G. (2007). Amniotic membrane transplantation with fibrin glue for conjunctivochalasis. American Journal of Ophthalmology, 144(2), 311\u2013313. https:\/\/doi.org\/10.1016\/j.ajo.2007.03.044","journal-title":"American Journal of Ophthalmology"},{"issue":"5","key":"10892_CR117","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1016\/S0002-9394(00)00600-0","volume":"130","author":"DL Budenz","year":"2000","unstructured":"Budenz, D. L., Barton, K., & Tseng, S. C. G. (2000). Amniotic membrane transplantation for repair of leaking glaucoma filtering blebs. American Journal of Ophthalmology, 130(5), 580\u2013588. https:\/\/doi.org\/10.1016\/S0002-9394(00)00600-0","journal-title":"American Journal of Ophthalmology"},{"key":"10892_CR118","unstructured":"Unpacking the Regulations: Understand 21 CFR 1271. (n.d.). Retrieved 8 April 2025, from https:\/\/msbdocs.com\/security-compliance\/what-is-21-cfr-1271\/"},{"issue":"1","key":"10892_CR119","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1111\/iwj.12843","volume":"15","author":"C Bianchi","year":"2018","unstructured":"Bianchi, C., Cazzell, S., Vayser, D., Reyzelman, A. M., Dosluoglu, H., & Tovmassian, G. (2018). A multicentre randomised controlled trial evaluating the efficacy of dehydrated human amnion\/chorion membrane (EpiFix \u00ae ) allograft for the treatment of venous leg ulcers. International Wound Journal, 15(1), 114\u2013122. https:\/\/doi.org\/10.1111\/iwj.12843","journal-title":"International Wound Journal"},{"key":"10892_CR120","doi-asserted-by":"publisher","unstructured":"Marston, W. A., Lantis, J. C., Wu, S. C., Nouvong, A., Lee, T. D., McCoy, N. D., \u2026 Tseng, S. C. (2019). An open\u2010label trial of cryopreserved human umbilical cord in the treatment of complex diabetic foot ulcers complicated by osteomyelitis. Wound Repair and Regeneration, 27(6), 680\u2013686. https:\/\/doi.org\/10.1111\/wrr.12754","DOI":"10.1111\/wrr.12754"},{"key":"10892_CR121","unstructured":"Snyder, R. J., Shimozaki, K., Tallis, A., Kerzner, M., Reyzelman, A., Lintzeris, D., \u2026 Rosenblum, B. (2016). A prospective, randomized, multicenter, controlled evaluation of the use of dehydrated amniotic membrane allograft compared to standard of care for the closure of chronic diabetic foot ulcer. Wounds: A Compendium of Clinical Research and Practice, 28(3), 70\u20137."},{"key":"10892_CR122","doi-asserted-by":"publisher","unstructured":"L\u00f3pez\u2010Valladares, M. J., Teresa Rodr\u00edguez\u2010Ares, M., Touri\u00f1o, R., Gude, F., Teresa Silva, M., & Couceiro, J. (2010). Donor age and gestational age influence on growth factor levels in human amniotic membrane. Acta Ophthalmologica, 88(6). https:\/\/doi.org\/10.1111\/j.1755-3768.2010.01908.x","DOI":"10.1111\/j.1755-3768.2010.01908.x"},{"issue":"10","key":"10892_CR123","doi-asserted-by":"publisher","first-page":"531","DOI":"10.3390\/jfb14100531","volume":"14","author":"AL Ingraldi","year":"2023","unstructured":"Ingraldi, A. L., Audet, R. G., & Tabor, A. J. (2023). The preparation and clinical efficacy of amnion-derived membranes: A review. Journal of Functional Biomaterials, 14(10), 531. https:\/\/doi.org\/10.3390\/jfb14100531","journal-title":"Journal of Functional Biomaterials"},{"key":"10892_CR124","unstructured":"Fda, & Cber. (2020). Regulatory considerations for human cells, tissues, and cellular and tissue-based products: Minimal manipulation and homologous use guidance for industry and food and drug administration staff contains nonbinding recommendations regulatory considerations for human cells, tissues, and cellular and tissue-based products: Minimal manipulation and homologous use guidance for industry and food and drug administration staff. Retrieved from https:\/\/www.fda.gov\/CombinationProducts\/default.htm"},{"key":"10892_CR125","unstructured":"Planned Parenthood of Southeastern Pa. v. Casey| 505 U.S. 833 (1992)| Justia U.S. Supreme Court Center. (n.d.). Retrieved 29 September 2024, from https:\/\/supreme.justia.com\/cases\/federal\/us\/505\/833\/"},{"key":"10892_CR126","unstructured":"Law No. 67\/98 of 26 October (Personal Data), Portugal, WIPO Lex. (n.d.). Retrieved 29 September 2024, from https:\/\/www.wipo.int\/wipolex\/en\/legislation\/details\/3537"},{"key":"10892_CR127","unstructured":"Directive 2004\/23\/EC of the European Parliament and of the Council of 31 March 2004 on setting standards of quality and safety for the donation, procurement, testing, processing, preservation, storage and distribution of human tissues and cells. (n.d.). Retrieved 29 September 2024, from https:\/\/www.legislation.gov.uk\/eudr\/2004\/23\/article\/12"},{"issue":"5","key":"10892_CR128","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1007\/s12015-018-9834-9","volume":"14","author":"CA Cismaru","year":"2018","unstructured":"Cismaru, C. A., Pop, L., & Berindan-Neagoe, I. (2018). Incognito: Are microchimeric fetal stem cells that cross placental barrier real emissaries of peace? Stem Cell Reviews and Reports, 14(5), 632\u2013641. https:\/\/doi.org\/10.1007\/s12015-018-9834-9","journal-title":"Stem Cell Reviews and Reports"},{"issue":"2","key":"10892_CR129","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1038\/nrendo.2010.216","volume":"7","author":"L Fugazzola","year":"2011","unstructured":"Fugazzola, L., Cirello, V., & Beck-Peccoz, P. (2011). Fetal microchimerism as an explanation of disease. Nature Reviews Endocrinology, 7(2), 89\u201397. https:\/\/doi.org\/10.1038\/nrendo.2010.216","journal-title":"Nature Reviews Endocrinology"},{"issue":"2","key":"10892_CR130","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1016\/j.ejogrb.2011.05.008","volume":"158","author":"C Boyon","year":"2011","unstructured":"Boyon, C., Collinet, P., Boulanger, L., Rubod, C., Lucot, J. P., & Vinatier, D. (2011). Fetal microchimerism: Benevolence or malevolence for the mother? European Journal of Obstetrics & Gynecology and Reproductive Biology, 158(2), 148\u2013152. https:\/\/doi.org\/10.1016\/j.ejogrb.2011.05.008","journal-title":"European Journal of Obstetrics & Gynecology and Reproductive Biology"},{"issue":"2","key":"10892_CR131","doi-asserted-by":"publisher","first-page":"40","DOI":"10.4161\/chim.28746","volume":"5","author":"U Mahmood","year":"2014","unstructured":"Mahmood, U., & O\u2019Donoghue, K. (2014). Microchimeric fetal cells play a role in maternal wound healing after pregnancy. Chimerism, 5(2), 40\u201352. https:\/\/doi.org\/10.4161\/chim.28746","journal-title":"Chimerism"},{"key":"10892_CR132","doi-asserted-by":"publisher","unstructured":"Surico, P. L., Barone, V., Singh, R. B., Coassin, M., Blanco, T., Dohlman, T. H., \u2026 Di Zazzo, A. (2024). Potential applications of mesenchymal stem cells in ocular surface immune-mediated disorders. Survey of Ophthalmology. https:\/\/doi.org\/10.1016\/J.SURVOPHTHAL.2024.07.008","DOI":"10.1016\/J.SURVOPHTHAL.2024.07.008"},{"key":"10892_CR133","doi-asserted-by":"publisher","unstructured":"Surico, P. L., Scarabosio, A., Miotti, G., Grando, M., Salati, C., Parodi, P. C., \u2026 Zeppieri, M. (2024). Unlocking the versatile potential: Adipose-derived mesenchymal stem cells in ocular surface reconstruction and oculoplastics. World Journal of Stem Cells, 16(2), 89\u2013101. https:\/\/doi.org\/10.4252\/WJSC.V16.I2.89","DOI":"10.4252\/WJSC.V16.I2.89"},{"key":"10892_CR134","doi-asserted-by":"publisher","unstructured":"Shayan Asl, N., Nejat, F., Mohammadi, P., Nekoukar, A., Hesam, S., Ebrahimi, M., & Jadidi, K. (2019). Amniotic membrane extract eye drop promotes limbal stem cell proliferation and corneal epithelium healing. Cell Journal, 20(4), 459\u2013468. https:\/\/doi.org\/10.22074\/cellj.2019.5423","DOI":"10.22074\/cellj.2019.5423"},{"key":"10892_CR135","doi-asserted-by":"publisher","unstructured":"Li, X., Li, P., Wang, C., Shang, T., Han, H., Tong, Y., \u2026 Cui, L. (2022). A thermo-sensitive and injectable hydrogel derived from a decellularized amniotic membrane to prevent intrauterine adhesion by accelerating endometrium regeneration. Biomaterials Science, 10(9), 2275\u20132286. https:\/\/doi.org\/10.1039\/D1BM01791H","DOI":"10.1039\/D1BM01791H"},{"issue":"4","key":"10892_CR136","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1016\/j.amjoto.2014.03.007","volume":"35","author":"K Iravani","year":"2014","unstructured":"Iravani, K., Hashemi, S. B., Tehrani, M., & Rashidi, M. (2014). Amniotic membrane in reconstruction of larynx following chondrosarcoma resection: A case report. American Journal of Otolaryngology, 35(4), 520\u2013523. https:\/\/doi.org\/10.1016\/j.amjoto.2014.03.007","journal-title":"American Journal of Otolaryngology"},{"issue":"8","key":"10892_CR137","doi-asserted-by":"publisher","first-page":"1625","DOI":"10.1007\/s00701-018-3577-x","volume":"160","author":"E Marton","year":"2018","unstructured":"Marton, E., Giordan, E., Gioffr\u00e8, G., Canova, G., Paolin, A., Mazzucco, M. G., & Longatti, P. (2018). Homologous cryopreserved amniotic membrane in the repair of myelomeningocele: Preliminary experience. Acta Neurochirurgica, 160(8), 1625\u20131631. https:\/\/doi.org\/10.1007\/s00701-018-3577-x","journal-title":"Acta Neurochirurgica"},{"key":"10892_CR138","doi-asserted-by":"publisher","unstructured":"Gr\u00e9mare, A., Thibes, L., Gluais, M., Torres, Y., Potart, D., Da Silva, N., \u2026 L\u2019Heureux, N. (2022). Development of a vascular substitute produced by weaving yarn made from human amniotic membrane. Biofabrication, 14(4), 045010. https:\/\/doi.org\/10.1088\/1758-5090\/ac84ae","DOI":"10.1088\/1758-5090\/ac84ae"},{"issue":"08","key":"10892_CR139","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1055\/s-0039-3400951","volume":"34","author":"KJ Alden","year":"2021","unstructured":"Alden, K. J., Harris, S., Hubbs, B., Kot, K., Istwan, N. B., & Mason, D. (2021). Micronized dehydrated human amnion chorion membrane injection in the treatment of knee osteoarthritis\u2014a large retrospective case series. The Journal of Knee Surgery, 34(08), 841\u2013845. https:\/\/doi.org\/10.1055\/s-0039-3400951","journal-title":"The Journal of Knee Surgery"},{"issue":"19","key":"10892_CR140","doi-asserted-by":"publisher","first-page":"4559","DOI":"10.3390\/molecules25194559","volume":"25","author":"H Sadidi","year":"2020","unstructured":"Sadidi, H., Hooshmand, S., Ahmadabadi, A., Javad Hoseini, S., Baino, F., Vatanpour, M., & Kargozar, S. (2020). Cerium oxide nanoparticles (Nanoceria): Hopes in soft tissue engineering. Molecules, 25(19), 4559. https:\/\/doi.org\/10.3390\/molecules25194559","journal-title":"Molecules"},{"key":"10892_CR141","doi-asserted-by":"publisher","first-page":"107797","DOI":"10.1016\/j.exer.2019.107797","volume":"188","author":"A Tisi","year":"2019","unstructured":"Tisi, A., Passacantando, M., Ciancaglini, M., & Maccarone, R. (2019). Nanoceria neuroprotective effects in the light-damaged retina: A focus on retinal function and microglia activation. Experimental Eye Research, 188, 107797. https:\/\/doi.org\/10.1016\/j.exer.2019.107797","journal-title":"Experimental Eye Research"},{"issue":"2","key":"10892_CR142","doi-asserted-by":"publisher","first-page":"e16733","DOI":"10.1371\/journal.pone.0016733","volume":"6","author":"X Zhou","year":"2011","unstructured":"Zhou, X., Wong, L. L., Karakoti, A. S., Seal, S., & McGinnis, J. F. (2011). Nanoceria Inhibit the development and promote the regression of pathologic retinal neovascularization in the Vldlr knockout mouse. PLoS ONE, 6(2), e16733. https:\/\/doi.org\/10.1371\/journal.pone.0016733","journal-title":"PLoS ONE"},{"key":"10892_CR143","doi-asserted-by":"publisher","unstructured":"Krzastek, S. C., & Smith, R. (2019). An update on the best approaches to prevent complications in penile prosthesis recipients. Therapeutic Advances in Urology, 11. https:\/\/doi.org\/10.1177\/1756287218818076","DOI":"10.1177\/1756287218818076"},{"key":"10892_CR144","doi-asserted-by":"publisher","first-page":"227","DOI":"10.2147\/IMCRJ.S402005","volume":"16","author":"FD Siregar","year":"2023","unstructured":"Siregar, F. D., & Hidayat, W. (2023). The role of vitamin D on the wound healing process: A case series. International Medical Case Reports Journal, 16, 227\u2013232. https:\/\/doi.org\/10.2147\/IMCRJ.S402005","journal-title":"International Medical Case Reports Journal"},{"issue":"16","key":"10892_CR145","doi-asserted-by":"publisher","first-page":"2114","DOI":"10.3390\/cells12162114","volume":"12","author":"MK Arki","year":"2023","unstructured":"Arki, M. K., Moeinabadi-Bidgoli, K., Hossein-Khannazer, N., Gramignoli, R., Najimi, M., & Vosough, M. (2023). Amniotic membrane and its derivatives: Novel therapeutic modalities in liver disorders. Cells, 12(16), 2114. https:\/\/doi.org\/10.3390\/cells12162114","journal-title":"Cells"},{"issue":"2","key":"10892_CR146","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1007\/s10561-025-10167-2","volume":"26","author":"G Anoop","year":"2025","unstructured":"Anoop, G., Kamaraj, M., Nithya, T. G., Babu, P. R., & Babu, S. S. (2025). Lyophilization of dehydrated human amniotic membrane: A proactive approach to preserve growth factors for enhanced wound healing. Cell and Tissue Banking, 26(2), 18. https:\/\/doi.org\/10.1007\/s10561-025-10167-2","journal-title":"Cell and Tissue Banking"},{"issue":"1","key":"10892_CR147","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1186\/s12906-019-2525-5","volume":"19","author":"MS Rahman","year":"2019","unstructured":"Rahman, M. S., Islam, R., Rana, M. M., Spitzhorn, L.-S., Rahman, M. S., Adjaye, J., & Asaduzzaman, S. M. (2019). Characterization of burn wound healing gel prepared from human amniotic membrane and Aloe vera extract. BMC Complementary and Alternative Medicine, 19(1), 115. https:\/\/doi.org\/10.1186\/s12906-019-2525-5","journal-title":"BMC Complementary and Alternative Medicine"}],"container-title":["Stem Cell Reviews and Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12015-025-10892-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12015-025-10892-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12015-025-10892-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T14:49:53Z","timestamp":1757170193000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12015-025-10892-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,14]]},"references-count":147,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10892"],"URL":"https:\/\/doi.org\/10.1007\/s12015-025-10892-x","relation":{},"ISSN":["2629-3269","2629-3277"],"issn-type":[{"value":"2629-3269","type":"print"},{"value":"2629-3277","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,14]]},"assertion":[{"value":"27 April 2025","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 May 2025","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The authors declare no competing financial or non-financial interests related to the work submitted for publication.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}