{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T13:46:10Z","timestamp":1764510370538},"reference-count":74,"publisher":"Springer Science and Business Media LLC","issue":"2-3","license":[{"start":{"date-parts":[[2009,7,29]],"date-time":"2009-07-29T00:00:00Z","timestamp":1248825600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinic Rev Allerg Immunol"],"published-print":{"date-parts":[[2010,4]]},"DOI":"10.1007\/s12016-009-8164-8","type":"journal-article","created":{"date-parts":[[2009,7,28]],"date-time":"2009-07-28T08:50:56Z","timestamp":1248771056000},"page":"125-134","source":"Crossref","is-referenced-by-count":15,"title":["Contemporary Challenges in Mastocytosis"],"prefix":"10.1007","volume":"38","author":[{"given":"H. David","family":"Pettigrew","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne S.","family":"Teuber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James S.","family":"Kong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Eric","family":"Gershwin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,7,29]]},"reference":[{"key":"8164_CR1","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1136\/bmj.2.455.323","volume":"2","author":"E Nettleship","year":"1869","unstructured":"Nettleship E, Tay W (1869) Rare forms of urticaria. Br Med J 2:323\u2013330","journal-title":"Br Med J"},{"key":"8164_CR2","first-page":"367","volume":"19","author":"PG Unna","year":"1894","unstructured":"Unna PG (1894) Die spezifische farbung der mastzellenkornung. Monatsh Prakt Dermatol 19:367\u2013368","journal-title":"Monatsh Prakt Dermatol"},{"key":"8164_CR3","first-page":"426","volume":"48","author":"JM Ellis","year":"1949","unstructured":"Ellis JM (1949) Urticaria pigmentosa: a report of a case with autopsy. AMA Arch Pathol 48:426\u2013435","journal-title":"AMA Arch Pathol"},{"issue":"4","key":"8164_CR4","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1182\/blood-2007-11-078097","volume":"112","author":"DD Metcalfe","year":"2008","unstructured":"Metcalfe DD (2008) Mast cells and mastocytosis. Blood 112(4):946\u2013956","journal-title":"Blood"},{"key":"8164_CR5","first-page":"30","volume-title":"Heparin: its chemistry, physiology, and application in medicine","author":"J Jorpes","year":"1939","unstructured":"Jorpes J (1939) The site of formation of heparin. In: Jorpes JE (ed) Heparin: its chemistry, physiology, and application in medicine. Oxford University Press, Oxford, pp 30\u201339"},{"issue":"3064","key":"8164_CR6","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1126\/science.118.3064.332","volume":"118","author":"JF Riley","year":"1953","unstructured":"Riley JF (1953) Histamine in tissue mast cells. Science 118(3064):332","journal-title":"Science"},{"issue":"1","key":"8164_CR7","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/0955-2235(91)90011-R","volume":"3","author":"P Valent","year":"1991","unstructured":"Valent P, Sillaber C, Bettelheim P (1991) The growth and differentiation of mast cells. Prog Growth Factor Res 3(1):27\u201341","journal-title":"Prog Growth Factor Res"},{"issue":"7","key":"8164_CR8","doi-asserted-by":"crossref","first-page":"2333","DOI":"10.1182\/blood.V94.7.2333.419k30_2333_2342","volume":"94","author":"AS Kirshenbaum","year":"1999","unstructured":"Kirshenbaum AS et al (1999) Demonstration that human mast cells arise from a progenitor cell population that is CD34(+), c-kit(+), and expresses aminopeptidase N (CD13). Blood 94(7):2333\u20132342","journal-title":"Blood"},{"issue":"5","key":"8164_CR9","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.4049\/jimmunol.146.5.1410","volume":"146","author":"AS Kirshenbaum","year":"1991","unstructured":"Kirshenbaum AS et al (1991) Demonstration of the origin of human mast cells from CD34+ bone marrow progenitor cells. J Immunol 146(5):1410\u20131415","journal-title":"J Immunol"},{"issue":"1","key":"8164_CR10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF01966825","volume":"14","author":"AM Saavedra-Delgado","year":"1984","unstructured":"Saavedra-Delgado AM, Turpin S, Metcalfe DD (1984) Typical and atypical mast cells of the rat gastrointestinal system: distribution and correlation with tissue histamine. Agents Actions 14(1):1\u20137","journal-title":"Agents Actions"},{"issue":"4","key":"8164_CR11","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1152\/physrev.1997.77.4.1033","volume":"77","author":"DD Metcalfe","year":"1997","unstructured":"Metcalfe DD, Baram D, Mekori YA (1997) Mast cells. Physiol Rev 77(4):1033\u20131079","journal-title":"Physiol Rev"},{"issue":"3","key":"8164_CR12","doi-asserted-by":"crossref","first-page":"772","DOI":"10.4049\/jimmunol.148.3.772","volume":"148","author":"AS Kirshenbaum","year":"1992","unstructured":"Kirshenbaum AS et al (1992) Effect of IL-3 and stem cell factor on the appearance of human basophils and mast cells from CD34+ pluripotent progenitor cells. J Immunol 148(3):772\u2013777","journal-title":"J Immunol"},{"issue":"9","key":"8164_CR13","doi-asserted-by":"crossref","first-page":"2237","DOI":"10.1182\/blood.V80.9.2237.2237","volume":"80","author":"P Valent","year":"1992","unstructured":"Valent P et al (1992) Induction of differentiation of human mast cells from bone marrow and peripheral blood mononuclear cells by recombinant human stem cell factor\/kit-ligand in long-term culture. Blood 80(9):2237\u20132245","journal-title":"Blood"},{"issue":"7","key":"8164_CR14","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/S0145-2126(01)00041-8","volume":"25","author":"WR Sperr","year":"2001","unstructured":"Sperr WR et al (2001) Morphologic properties of neoplastic mast cells: delineation of stages of maturation and implication for cytological grading of mastocytosis. Leuk Res 25(7):529\u2013536","journal-title":"Leuk Res"},{"issue":"4","key":"8164_CR15","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1172\/JCI116761","volume":"92","author":"T Furitsu","year":"1993","unstructured":"Furitsu T et al (1993) Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product. J Clin Invest 92(4):1736\u20131744","journal-title":"J Clin Invest"},{"issue":"3","key":"8164_CR16","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1038\/ng0396-312","volume":"12","author":"BJ Longley","year":"1996","unstructured":"Longley BJ et al (1996) Somatic c-KIT activating mutation in urticaria pigmentosa and aggressive mastocytosis: establishment of clonality in a human mast cell neoplasm. Nat Genet 12(3):312\u2013314","journal-title":"Nat Genet"},{"issue":"23","key":"8164_CR17","doi-asserted-by":"crossref","first-page":"10560","DOI":"10.1073\/pnas.92.23.10560","volume":"92","author":"H Nagata","year":"1995","unstructured":"Nagata H et al (1995) Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder. Proc Natl Acad Sci U S A 92(23):10560\u201310564","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"6577","key":"8164_CR18","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1038\/381075a0","volume":"381","author":"B Echtenacher","year":"1996","unstructured":"Echtenacher B, Mannel DN, Hultner L (1996) Critical protective role of mast cells in a model of acute septic peritonitis. Nature 381(6577):75\u201377","journal-title":"Nature"},{"issue":"4","key":"8164_CR19","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1002\/eji.200323830","volume":"33","author":"S Varadaradjalou","year":"2003","unstructured":"Varadaradjalou S et al (2003) Toll-like receptor 2 (TLR2) and TLR4 differentially activate human mast cells. Eur J Immunol 33(4):899\u2013906","journal-title":"Eur J Immunol"},{"issue":"1","key":"8164_CR20","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.jaci.2004.03.049","volume":"114","author":"M Kulka","year":"2004","unstructured":"Kulka M et al (2004) Activation of mast cells by double-stranded RNA: evidence for activation through Toll-like receptor 3. J Allergy Clin Immunol 114(1):174\u2013182","journal-title":"J Allergy Clin Immunol"},{"issue":"3","key":"8164_CR21","doi-asserted-by":"crossref","first-page":"2S","DOI":"10.1111\/1523-1747.ep12468882","volume":"96","author":"DD Metcalfe","year":"1991","unstructured":"Metcalfe DD (1991) Classification and diagnosis of mastocytosis: current status. J Invest Dermatol 96(3):2S\u20134S","journal-title":"J Invest Dermatol"},{"issue":"7","key":"8164_CR22","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/S0145-2126(01)00038-8","volume":"25","author":"P Valent","year":"2001","unstructured":"Valent P et al (2001) Diagnostic criteria and classification of mastocytosis: a consensus proposal. Leuk Res 25(7):603\u2013625","journal-title":"Leuk Res"},{"issue":"1","key":"8164_CR23","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1385\/CRIAI:30:1:053","volume":"30","author":"JS Kong","year":"2006","unstructured":"Kong JS et al (2006) Mastocytosis: the great masquerader. Clin Rev Allergy Immunol 30(1):53\u201360","journal-title":"Clin Rev Allergy Immunol"},{"issue":"2","key":"8164_CR24","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1159\/000101711","volume":"74","author":"HP Horny","year":"2007","unstructured":"Horny HP, Sotlar K, Valent P (2007) Mastocytosis: state of the art. Pathobiology 74(2):121\u2013132","journal-title":"Pathobiology"},{"issue":"3","key":"8164_CR25","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/S0889-8588(05)70299-9","volume":"14","author":"K Hartmann","year":"2000","unstructured":"Hartmann K, Metcalfe DD (2000) Pediatric mastocytosis. Hematol Oncol Clin North Am 14(3):625\u2013640","journal-title":"Hematol Oncol Clin North Am"},{"issue":"7","key":"8164_CR26","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S0145-2126(01)00044-3","volume":"25","author":"K Wolff","year":"2001","unstructured":"Wolff K, Komar M, Petzelbauer P (2001) Clinical and histopathological aspects of cutaneous mastocytosis. Leuk Res 25(7):519\u2013528","journal-title":"Leuk Res"},{"issue":"2","key":"8164_CR27","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1159\/000048187","volume":"127","author":"K Hartmann","year":"2002","unstructured":"Hartmann K, Henz BM (2002) Cutaneous mastocytosis\u2014clinical heterogeneity. Int Arch Allergy Immunol 127(2):143\u2013146","journal-title":"Int Arch Allergy Immunol"},{"issue":"1","key":"8164_CR28","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0190-9622(83)80312-0","volume":"8","author":"G Roupe","year":"1983","unstructured":"Roupe G, Granerus G, Olafson JH (1983) Urticaria pigmentosa or systemic mastocytosis? J Am Acad Dermatol 8(1):137","journal-title":"J Am Acad Dermatol"},{"issue":"2","key":"8164_CR29","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.iac.2004.01.002","volume":"24","author":"K Brockow","year":"2004","unstructured":"Brockow K (2004) Urticaria pigmentosa. Immunol Allergy Clin North Am 24(2):287\u2013316 vii","journal-title":"Immunol Allergy Clin North Am"},{"issue":"3","key":"8164_CR30","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1093\/ajcp\/109.3.279","volume":"109","author":"G Topar","year":"1998","unstructured":"Topar G et al (1998) Urticaria pigmentosa: a clinical, hematopathologic, and serologic study of 30 adults. Am J Clin Pathol 109(3):279\u2013285","journal-title":"Am J Clin Pathol"},{"key":"8164_CR31","first-page":"353","volume":"34","author":"GH Findlay","year":"1960","unstructured":"Findlay GH, Schulz EJ, Pepler WJ (1960) Diffuse cutaneous mastocytosis. S Afr Med J 34:353\u2013356","journal-title":"S Afr Med J"},{"issue":"3","key":"8164_CR32","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1046\/j.1525-1470.2000.01751.x","volume":"17","author":"LM Waxtein","year":"2000","unstructured":"Waxtein LM et al (2000) Diffuse cutaneous mastocytosis with bone marrow infiltration in a child: a case report. Pediatr Dermatol 17(3):198\u2013201","journal-title":"Pediatr Dermatol"},{"issue":"5","key":"8164_CR33","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1111\/j.1365-2133.1980.tb07663.x","volume":"102","author":"R Willemze","year":"1980","unstructured":"Willemze R et al (1980) Diffuse cutaneous mastocytosis with multiple cutaneous mastocytomas. Report of a case with clinical, histopathological and ultrastructural aspects. Br J Dermatol 102(5):601\u2013607","journal-title":"Br J Dermatol"},{"issue":"1","key":"8164_CR34","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/BF00750728","volume":"412","author":"O Scheck","year":"1987","unstructured":"Scheck O et al (1987) Solitary mastocytoma of the eyelid. A case report with special reference to the immunocytology of human tissue mast cells, and a review of the literature. Virchows Arch A Pathol Anat Histopathol 412(1):31\u201336","journal-title":"Virchows Arch A Pathol Anat Histopathol"},{"issue":"2","key":"8164_CR35","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1159\/000059404","volume":"128","author":"WR Sperr","year":"2002","unstructured":"Sperr WR et al (2002) Serum tryptase levels in patients with mastocytosis: correlation with mast cell burden and implication for defining the category of disease. Int Arch Allergy Immunol 128(2):136\u2013141","journal-title":"Int Arch Allergy Immunol"},{"issue":"3","key":"8164_CR36","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.iac.2006.05.010","volume":"26","author":"LB Schwartz","year":"2006","unstructured":"Schwartz LB (2006) Diagnostic value of tryptase in anaphylaxis and mastocytosis. Immunol Allergy Clin North Am 26(3):451\u2013463","journal-title":"Immunol Allergy Clin North Am"},{"issue":"6","key":"8164_CR37","doi-asserted-by":"crossref","first-page":"2702","DOI":"10.1172\/JCI118337","volume":"96","author":"LB Schwartz","year":"1995","unstructured":"Schwartz LB et al (1995) The alpha form of human tryptase is the predominant type present in blood at baseline in normal subjects and is elevated in those with systemic mastocytosis. J Clin Invest 96(6):2702\u20132710","journal-title":"J Clin Invest"},{"issue":"26","key":"8164_CR38","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1056\/NEJM198706253162603","volume":"316","author":"LB Schwartz","year":"1987","unstructured":"Schwartz LB et al (1987) Tryptase levels as an indicator of mast-cell activation in systemic anaphylaxis and mastocytosis. N Engl J Med 316(26):1622\u20131626","journal-title":"N Engl J Med"},{"issue":"3","key":"8164_CR39","doi-asserted-by":"crossref","first-page":"119","DOI":"10.2500\/108854194778702946","volume":"15","author":"LB Schwartz","year":"1994","unstructured":"Schwartz LB (1994) Tryptase: a clinical indicator of mast cell-dependent events. Allergy Proc 15(3):119\u2013123","journal-title":"Allergy Proc"},{"key":"8164_CR40","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1146\/annurev.med.55.091902.103822","volume":"55","author":"C Akin","year":"2004","unstructured":"Akin C, Metcalfe DD (2004) Systemic mastocytosis. Annu Rev Med 55:419\u2013432","journal-title":"Annu Rev Med"},{"issue":"2","key":"8164_CR41","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1309\/Q2WJ-46CL-YRFT-M5JF","volume":"116","author":"EC Stevens","year":"2001","unstructured":"Stevens EC, Rosenthal NS (2001) Bone marrow mast cell morphologic features and hematopoietic dyspoiesis in systemic mast cell disease. Am J Clin Pathol 116(2):177\u2013182","journal-title":"Am J Clin Pathol"},{"issue":"4","key":"8164_CR42","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1046\/j.1365-2141.2003.04125.x","volume":"120","author":"A Pardanani","year":"2003","unstructured":"Pardanani A et al (2003) Differential expression of CD2 on neoplastic mast cells in patients with systemic mast cell disease with and without an associated clonal haematological disorder. Br J Haematol 120(4):691\u2013694","journal-title":"Br J Haematol"},{"issue":"5","key":"8164_CR43","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1053\/hupa.2001.24319","volume":"32","author":"JH Jordan","year":"2001","unstructured":"Jordan JH et al (2001) Immunohistochemical properties of bone marrow mast cells in systemic mastocytosis: evidence for expression of CD2, CD117\/Kit, and bcl-x(L). Hum Pathol 32(5):545\u2013552","journal-title":"Hum Pathol"},{"issue":"4","key":"8164_CR44","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1073\/pnas.96.4.1609","volume":"96","author":"BJ Longley Jr","year":"1999","unstructured":"Longley BJ Jr et al (1999) Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis. Proc Natl Acad Sci U S A 96(4):1609\u20131614","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"2","key":"8164_CR45","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/S0301-472X(99)00145-9","volume":"28","author":"C Akin","year":"2000","unstructured":"Akin C et al (2000) Analysis of the surface expression of c-kit and occurrence of the c-kit Asp816Val activating mutation in T cells, B cells, and myelomonocytic cells in patients with mastocytosis. Exp Hematol 28(2):140\u2013147","journal-title":"Exp Hematol"},{"issue":"2","key":"8164_CR46","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1159\/000048179","volume":"127","author":"F Feger","year":"2002","unstructured":"Feger F et al (2002) Kit and c-kit mutations in mastocytosis: a short overview with special reference to novel molecular and diagnostic concepts. Int Arch Allergy Immunol 127(2):110\u2013114","journal-title":"Int Arch Allergy Immunol"},{"issue":"1","key":"8164_CR47","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0002-9440(10)63120-3","volume":"164","author":"K Kemmer","year":"2004","unstructured":"Kemmer K et al (2004) KIT mutations are common in testicular seminomas. Am J Pathol 164(1):305\u2013313","journal-title":"Am J Pathol"},{"issue":"8","key":"8164_CR48","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1136\/jcp.56.8.575","volume":"56","author":"HP Horny","year":"2003","unstructured":"Horny HP et al (2003) Increase of bone marrow lymphocytes in systemic mastocytosis: reactive lymphocytosis or malignant lymphoma? Immunohistochemical and molecular findings on routinely processed bone marrow biopsy specimens. J Clin Pathol 56(8):575\u2013578","journal-title":"J Clin Pathol"},{"issue":"6","key":"8164_CR49","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/jid.1952.51","volume":"18","author":"F Sagher","year":"1952","unstructured":"Sagher F, Cohen C, Schorr S (1952) Concomitant bone changes in urticaria pigmentosa. J Invest Dermatol 18(6):425\u2013432","journal-title":"J Invest Dermatol"},{"issue":"8","key":"8164_CR50","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.1182\/blood.V91.8.2731.2731_2731_2736","volume":"91","author":"L Escribano","year":"1998","unstructured":"Escribano L et al (1998) Indolent systemic mast cell disease in adults: immunophenotypic characterization of bone marrow mast cells and its diagnostic implications. Blood 91(8):2731\u20132736","journal-title":"Blood"},{"issue":"6","key":"8164_CR51","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1136\/jcp.2003.014860","volume":"57","author":"HP Horny","year":"2004","unstructured":"Horny HP et al (2004) Systemic mastocytosis with associated clonal haematological non-mast cell lineage diseases: a histopathological challenge. J Clin Pathol 57(6):604\u2013608","journal-title":"J Clin Pathol"},{"issue":"2","key":"8164_CR52","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1111\/j.1365-2141.1990.tb07870.x","volume":"76","author":"HP Horny","year":"1990","unstructured":"Horny HP et al (1990) Blood findings in generalized mastocytosis: evidence of frequent simultaneous occurrence of myeloproliferative disorders. Br J Haematol 76(2):186\u2013193","journal-title":"Br J Haematol"},{"issue":"5\u20136","key":"8164_CR53","doi-asserted-by":"crossref","first-page":"473","DOI":"10.3109\/10428190009058500","volume":"37","author":"WR Sperr","year":"2000","unstructured":"Sperr WR et al (2000) Clinical and biologic diversity of leukemias occurring in patients with mastocytosis. Leuk Lymphoma 37(5\u20136):473\u2013486","journal-title":"Leuk Lymphoma"},{"issue":"12","key":"8164_CR54","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/S0025-6196(12)62636-6","volume":"61","author":"WD Travis","year":"1986","unstructured":"Travis WD et al (1986) Mast cell leukemia: report of a case and review of the literature. Mayo Clin Proc 61(12):957\u2013966","journal-title":"Mayo Clin Proc"},{"issue":"3","key":"8164_CR55","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/S0889-8588(05)70301-4","volume":"14","author":"AS Worobec","year":"2000","unstructured":"Worobec AS (2000) Treatment of systemic mast cell disorders. Hematol Oncol Clin North Am 14(3):659\u2013687 vii","journal-title":"Hematol Oncol Clin North Am"},{"issue":"2","key":"8164_CR56","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1097\/00043426-200102000-00014","volume":"23","author":"PP Guenther","year":"2001","unstructured":"Guenther PP et al (2001) Temporary response of localized intracranial mast cell sarcoma to combination chemotherapy. J Pediatr Hematol Oncol 23(2):134\u2013138","journal-title":"J Pediatr Hematol Oncol"},{"issue":"6","key":"8164_CR57","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1136\/jcp.39.6.596","volume":"39","author":"HP Horny","year":"1986","unstructured":"Horny HP et al (1986) Mast cell sarcoma of the larynx. J Clin Pathol 39(6):596\u2013602","journal-title":"J Clin Pathol"},{"issue":"7","key":"8164_CR58","first-page":"739","volume":"12","author":"M Kojima","year":"1999","unstructured":"Kojima M et al (1999) Mast cell sarcoma with tissue eosinophilia arising in the ascending colon. Mod Pathol 12(7):739\u2013743","journal-title":"Mod Pathol"},{"issue":"2","key":"8164_CR59","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1159\/000048190","volume":"127","author":"K Wolff","year":"2002","unstructured":"Wolff K (2002) Treatment of cutaneous mastocytosis. Int Arch Allergy Immunol 127(2):156\u2013159","journal-title":"Int Arch Allergy Immunol"},{"key":"8164_CR60","unstructured":"Castells M, Akin C (2008) Treatment and prognosis of mastocytosis (cutaneous and systemic). Up to Date; www.utdol.com , accessed 9 Apr 2009"},{"issue":"6","key":"8164_CR61","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/j.1365-2362.2007.01807.x","volume":"37","author":"P Valent","year":"2007","unstructured":"Valent P et al (2007) Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria. Eur J Clin Invest 37(6):435\u2013453","journal-title":"Eur J Clin Invest"},{"issue":"3","key":"8164_CR62","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.iac.2006.05.009","volume":"26","author":"TM Wilson","year":"2006","unstructured":"Wilson TM, Metcalfe DD, Robyn J (2006) Treament of systemic mastocytosis. Immunol Allergy Clin Nort Am 26(3):549-573","journal-title":"Immunol Allergy Clin Nort Am"},{"issue":"3","key":"8164_CR63","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.beha.2005.07.010","volume":"19","author":"A Pardanani","year":"2006","unstructured":"Pardanani A, Akin C, Valent P (2006) Pathogenesis, clinical features, and treatment advances in mastocytosis. Best Pract Res Clin Haematol 19(3):595-615","journal-title":"Best Pract Res Clin Haematol"},{"issue":"2","key":"8164_CR64","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.jaci.2007.11.010","volume":"121","author":"D Gonzalez de Olano","year":"2008","unstructured":"Gonzalez de Olano D et al (2008) Safety and effectiveness of immunotherapy in patients with indolent systemic mastocytois presenting with Hymenoptera venom anaphylaxis. J Allergy Clin Immunol 121(2):519-526","journal-title":"J Allergy Clin Immunol"},{"issue":"9","key":"8164_CR65","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1056\/NEJM199202273260907","volume":"326","author":"HC Kluin-Nelemans","year":"1992","unstructured":"Kluin-Nelemans HC et al (1992) Response to interferon alfa-2b in a patient with systemic mastocytosis. N Engl J Med 326(9):619\u2013623","journal-title":"N Engl J Med"},{"issue":"4","key":"8164_CR66","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1056\/NEJM200101253440415","volume":"344","author":"A Tefferi","year":"2001","unstructured":"Tefferi A et al (2001) Treatment of systemic mast-cell disease with cladribine. N Engl J Med 344(4):307\u2013309","journal-title":"N Engl J Med"},{"issue":"13","key":"8164_CR67","doi-asserted-by":"crossref","first-page":"4270","DOI":"10.1182\/blood-2003-05-1699","volume":"102","author":"HC Kluin-Nelemans","year":"2003","unstructured":"Kluin-Nelemans HC et al (2003) Cladribine therapy for systemic mastocytosis. Blood 102(13):4270\u20134276","journal-title":"Blood"},{"issue":"5","key":"8164_CR68","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1046\/j.1365-2141.2003.04575.x","volume":"122","author":"P Valent","year":"2003","unstructured":"Valent P et al (2003) Diagnosis and treatment of systemic mastocytosis: state of the art. Br J Haematol 122(5):695\u2013717","journal-title":"Br J Haematol"},{"issue":"9383","key":"8164_CR69","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0140-6736(03)14115-3","volume":"362","author":"A Pardanani","year":"2003","unstructured":"Pardanani A et al (2003) Imatinib for systemic mast-cell disease. Lancet 362(9383):535\u2013536","journal-title":"Lancet"},{"issue":"8","key":"8164_CR70","doi-asserted-by":"crossref","first-page":"3222","DOI":"10.1182\/blood-2003-11-3816","volume":"103","author":"C Akin","year":"2004","unstructured":"Akin C et al (2004) A novel form of mastocytosis associated with a transmembrane c-kit mutation and response to imatinib. Blood 103(8):3222\u20133225","journal-title":"Blood"},{"issue":"5","key":"8164_CR71","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1182\/blood.V99.5.1741","volume":"99","author":"Y Ma","year":"2002","unstructured":"Ma Y et al (2002) The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations. Blood 99(5):1741\u20131744","journal-title":"Blood"},{"issue":"8","key":"8164_CR72","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/S0301-472X(03)00112-7","volume":"31","author":"C Akin","year":"2003","unstructured":"Akin C et al (2003) Effects of tyrosine kinase inhibitor STI571 on human mast cells bearing wild-type or mutated c-kit. Exp Hematol 31(8):686\u2013692","journal-title":"Exp Hematol"},{"issue":"4","key":"8164_CR73","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.leukres.2003.09.001","volume":"28","author":"P Musto","year":"2004","unstructured":"Musto P et al (2004) Inefficacy of imatinib-mesylate in sporadic, aggressive systemic mastocytosis. Leuk Res 28(4):421\u2013422","journal-title":"Leuk Res"},{"issue":"8","key":"8164_CR74","doi-asserted-by":"crossref","first-page":"2865","DOI":"10.1182\/blood-2005-04-1568","volume":"106","author":"J Gotlib","year":"2005","unstructured":"Gotlib J et al (2005) Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation. Blood 106(8):2865\u20132870","journal-title":"Blood"}],"container-title":["Clinical Reviews in Allergy &amp; Immunology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12016-009-8164-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12016-009-8164-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12016-009-8164-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T04:51:02Z","timestamp":1685076662000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12016-009-8164-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7,29]]},"references-count":74,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[2010,4]]}},"alternative-id":["8164"],"URL":"https:\/\/doi.org\/10.1007\/s12016-009-8164-8","relation":{},"ISSN":["1080-0549","1559-0267"],"issn-type":[{"value":"1080-0549","type":"print"},{"value":"1559-0267","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,7,29]]}}}