{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T12:04:25Z","timestamp":1782216265643,"version":"3.54.5"},"reference-count":88,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2010,12,18]],"date-time":"2010-12-18T00:00:00Z","timestamp":1292630400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinic Rev Allerg Immunol"],"published-print":{"date-parts":[[2011,10]]},"DOI":"10.1007\/s12016-010-8214-2","type":"journal-article","created":{"date-parts":[[2010,12,17]],"date-time":"2010-12-17T07:42:02Z","timestamp":1292571722000},"page":"126-138","source":"Crossref","is-referenced-by-count":73,"title":["Recent Concepts of Autoimmune Pancreatitis and IgG4-Related Disease"],"prefix":"10.1007","volume":"41","author":[{"given":"Kazuichi","family":"Okazaki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazushige","family":"Uchida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Miyoshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsukasa","family":"Ikeura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Takaoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akiyoshi","family":"Nishio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,12,18]]},"reference":[{"key":"8214_CR1","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1007\/BF02232341","volume":"6","author":"H Sarles","year":"1961","unstructured":"Sarles H, Sarles JC, Muratore R, Guien C (1961) Chronic inflammatory sclerosis of the pancreas\u2014an autonomous pancreatic disease? Am J Dig Dis 6:688\u2013698","journal-title":"Am J Dig Dis."},{"key":"8214_CR2","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1007\/BF02285209","volume":"40","author":"K Yoshida","year":"1995","unstructured":"Yoshida K, Toki F, Takeuchi T, Watanabe S, Shiratori K, Hayashi N (1995) Chronic pancreatitis caused by an autoimmune abnormality. Proposal of the concept of autoimmune pancreatitis. Dig Dis Sci 40:1561\u20131568","journal-title":"Dig Dis Sci."},{"key":"8214_CR3","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1056\/NEJM200103083441005","volume":"344","author":"H Hamano","year":"1995","unstructured":"Hamano H, Kawa S, Horiuchi A et al (1995) High serum IgG4 concentrations in patients with sclerosing pancreatitis. New Engl J Med 344:732\u2013738","journal-title":"New Engl J Med"},{"key":"8214_CR4","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s005350170094","volume":"36","author":"K Okazaki","year":"2001","unstructured":"Okazaki K, Uchida K, Chiba T (2001) Recent concept of autoimmune-related pancreatitis. J Gastroenterol 36:293\u2013302","journal-title":"J Gastroenterol."},{"key":"8214_CR5","first-page":"59","volume-title":"Target organ toxicology series, Toxicology of the pancreas","author":"K Okazaki","year":"2006","unstructured":"Okazaki K (2006) Autoimmune pancreatitis\u2014recent concept. In: Parviz M (ed) Target organ toxicology series, Toxicology of the pancreas. Taylor & Francis, Boca Raton, pp 59\u201373"},{"key":"8214_CR6","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1038\/ncpgasthep0837","volume":"4","author":"T Pickartz","year":"2007","unstructured":"Pickartz T, Mayerle J, Lerch M (2007) Autoimmune pancreatitis. Nat Clin Pract Gastroenterol Hepatol 4:314\u2013323","journal-title":"Nat Clin Pract Gastroenterol Hepatol"},{"key":"8214_CR7","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/0046-8177(91)90087-6","volume":"22","author":"K Kawaguchi","year":"1991","unstructured":"Kawaguchi K, Koike M, Tsuruta K, Okamoto A, Tabata I, Fujita N (1991) Lymphoplasmacytic sclerosing pancreatitis with cholangitis: a variant of primary sclerosing cholangitis extensively involving pancreas. Hum Pathol 22:387\u2013395","journal-title":"Hum Pathol."},{"key":"8214_CR8","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1007\/s00535-003-1175-y","volume":"38","author":"T Kamisawa","year":"2003","unstructured":"Kamisawa T, Funata N, Hayashi Y et al (2003) A new clinicopathological entity of IgG4-related autoimmune disease. J Gastroenterol 38:982\u2013984","journal-title":"J Gastroenterol"},{"key":"8214_CR9","doi-asserted-by":"crossref","first-page":"884","DOI":"10.7326\/0003-4819-66-5-884","volume":"66","author":"DE Comings","year":"1967","unstructured":"Comings DE et al (1967) Familial multifocal fibrosclerosis. Ann Intern Med 66:884\u2013892","journal-title":"Ann Intern Med"},{"key":"8214_CR10","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1097\/MPA.0b013e3181e4d9e5","volume":"39","author":"ST Chari","year":"2010","unstructured":"Chari ST, Kloeppel G, Zhang L et al (2010) Histopathologic and clinical subtypes of autoimmune pancreatitis: the Honolulu consensus document. Pancreas 39:549\u2013554","journal-title":"Pancreas"},{"key":"8214_CR11","first-page":"610","volume-title":"\u00dcber eine eigenartige symmetrishe Erkrankung der Tr\u00e4nen und Mundspeicheldr\u00fcsen","author":"J Mikulicz","year":"1892","unstructured":"Mikulicz J (1892) \u00dcber eine eigenartige symmetrishe Erkrankung der Tr\u00e4nen und Mundspeicheldr\u00fcsen. Beitr z Chir Fesrschr f Theodor Billroth, Stuttgart, pp 610\u2013630"},{"key":"8214_CR12","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1007\/s00535-006-1868-0","volume":"41","author":"K Okazaki","year":"2006","unstructured":"Okazaki K, Kawa S, Kamisawa T et al (2006) Clinical diagnostic criteria of autoimmune pancreatitis: revised proposal. J Gastroenterol 41:626\u2013631","journal-title":"J Gastroenterol"},{"key":"8214_CR13","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1007\/s00535-006-1862-6","volume":"41","author":"T Kamisawa","year":"2006","unstructured":"Kamisawa T, Okamoto A (2006) Autoimmune pancreatitis: proposal of IgG4-related sclerosing disease. J Gastroenterol 41:613\u2013625","journal-title":"J Gastroenterol"},{"key":"8214_CR14","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/s10165-006-0518-Y","volume":"16","author":"M Yamamoto","year":"2006","unstructured":"Yamamoto M, Takahashi H, Ohara M et al (2006) A new conceptualization for Mikulicz\u2019s disease as an IgG4-related plasmacytic disease. Mod Rheumatol 16:335\u2013340","journal-title":"Mod Rheumatol"},{"key":"8214_CR15","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1136\/ard.2008.089169","volume":"68","author":"Y Masaki","year":"2009","unstructured":"Masaki Y, Dong L, Kurose N et al (2009) Proposal for a new clinical entity, IgG4-positive multi-organ lymphoproliferative syndrome: analysis of 64 cases of IgG4-related disorders. Ann Rheum Dis 68:1310\u20131315","journal-title":"Ann Rheum Dis"},{"key":"8214_CR16","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1097\/00000478-200308000-00009","volume":"27","author":"K Notohara","year":"2003","unstructured":"Notohara K, Burgart LJ, Yadav D et al (2003) Idiopathic chronic pancreatitis with periductal lymphoplasmacytic infiltration: clinico-pathologic features of 35 cases. Am J Surg Pathol 27:1119\u20131127","journal-title":"Am J Surg Pathol"},{"key":"8214_CR17","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1007\/s00428-004-1140-z","volume":"445","author":"G Zamboni","year":"2004","unstructured":"Zamboni G, L\u00fcttges J, Capelli P et al (2004) Histopathological features of diagnostic and clinical relevance in autoimmune pancreatitis: a study on 53 resection specimens and 9 biopsy specimens. Virchows Arch 445:552\u2013563","journal-title":"Virchows Arch"},{"key":"8214_CR18","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1136\/gut.52.5.683","volume":"52","author":"T Kamisawa","year":"2003","unstructured":"Kamisawa T, Funata N, Hayashi Y et al (2003) Close relationship between autoimmune pancreatitis and multifocal fibrosclerosis. Gut 52:683\u2013687","journal-title":"Gut"},{"key":"8214_CR19","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1097\/00006676-200307000-00003","volume":"27","author":"H Saegusa","year":"2003","unstructured":"Saegusa H, Momose M, Kawa S et al (2003) Hilar and pancreatic gallium-67 accumulation is characteristic feature of autoimmune pancreatitis. Pancreas 27:20\u2013251","journal-title":"Pancreas"},{"key":"8214_CR20","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0140-6736(99)00603-0","volume":"354","author":"GW Erkelens","year":"1999","unstructured":"Erkelens GW, Vleggaar FP, Lesterhuis W et al (1999) Sclerosing pancreato-cholangitis responsive to steroid therapy. Lancet 354:43\u201344","journal-title":"Lancet"},{"key":"8214_CR21","first-page":"625","volume":"48","author":"T Nakazawa","year":"2001","unstructured":"Nakazawa T, Ohara H, Yamada T (2001) Atypical primary sclerosing cholangitis cases associated with unusual pancreatitis. Hepatogastroenterology 48:625\u2013630","journal-title":"Hepatogastroenterology."},{"key":"8214_CR22","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1016\/S0140-6736(02)08359-9","volume":"359","author":"H Hamano","year":"2002","unstructured":"Hamano H, Kawa S, Ochi Y et al (2002) Hydronephrosis associated with retroperitoneal fibrosis and sclerosing pancreatitis. Lancet 359:1403\u20131404","journal-title":"Lancet"},{"key":"8214_CR23","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1093\/ndt\/gfg477","volume":"19","author":"S Takeda","year":"2004","unstructured":"Takeda S, Haratake J, Kasai T et al (2004) IgG4-associated idiopathic tubulointerstitial nephritis complicating autoimmune pancreatitis. Nephrol Dial Transplant 19:474\u2013476","journal-title":"Nephrol Dial Transplant"},{"key":"8214_CR24","doi-asserted-by":"crossref","first-page":"e18","DOI":"10.1053\/j.ajkd.2003.12.006","volume":"43","author":"Y Uchiyama-Tanaka","year":"2004","unstructured":"Uchiyama-Tanaka Y, Mori Y, Kimura T et al (2004) Acute tubulointerstitial nephritis associated with autoimmune-related pancreatitis. Am J Kidney Dis 43:e18\u2013e25","journal-title":"Am J Kidney Dis"},{"key":"8214_CR25","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1507\/endocrj.K09E-277","volume":"56","author":"A Shimatsu","year":"2009","unstructured":"Shimatsu A, Oki Y, Fujisawa I et al (2009) Pituitary and stalk lesions (infundibulo-hypophysitis) associated with immunoglobulin G4-related systemic disease: an emerging clinical entity. Endocr J 56:1033\u20131041","journal-title":"Endocr J"},{"key":"8214_CR26","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1007\/s10620-005-2703-9","volume":"50","author":"K Komatsu","year":"2005","unstructured":"Komatsu K, Hamano H, Ochi Y et al (2005) High prevalence of hypothyroidism in patients with autoimmune pancreatitis. Dig Dis Sci 50:1052\u20131057","journal-title":"Dig Dis Sci"},{"key":"8214_CR27","doi-asserted-by":"crossref","first-page":"897","DOI":"10.2169\/internalmedicine.45.1752","volume":"45","author":"Y Yoshimura","year":"2006","unstructured":"Yoshimura Y, Takeda S, Ieki Y et al (2006) IgG4-associated prostatitis complicating autoimmune pancreatitis. Intern Med 45:897\u2013901","journal-title":"Intern Med"},{"issue":"Suppl 18","key":"8214_CR28","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1007\/s00535-007-2049-5","volume":"42","author":"K Okazaki","year":"2007","unstructured":"Okazaki K, Uchida K, Matsushita M et al (2007) How to diagnose autoimmune pancreatitis by the revised Japanese clinical criteria. J Gastroenterol 42(Suppl 18):32\u201338","journal-title":"J Gastroenterol"},{"key":"8214_CR29","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1097\/01.mpa.0000175178.85786.1d","volume":"31","author":"H Ohara","year":"2005","unstructured":"Ohara H, Nakazawa T, Sano H et al (2005) Systemic extrapancreatic lesions associated with autoimmune pancreatitis. Pancreas 31:232\u2013237","journal-title":"Pancreas"},{"key":"8214_CR30","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1007\/s00535-006-1908-9","volume":"41","author":"H Hamano","year":"2006","unstructured":"Hamano H, Arakura N, Muraki T et al (2006) Prevalence and distribution of extrapancreatic lesions complicating autoimmune pancreatitis. J Gastroenterol 41:1197\u20131205","journal-title":"J Gastroenterol"},{"key":"8214_CR31","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s00535-009-0197-5","volume":"45","author":"S Kawa","year":"2010","unstructured":"Kawa S, Okazaki K, Kamisawa T et al (2010) Japanese consensus guidelines for management of autoimmune pancreatitis: II. Extrapancreatic lesions, differential diagnosis. J Gastroenterol 45:355\u2013369","journal-title":"J Gastroenterol"},{"key":"8214_CR32","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1097\/MPA.0b013e3181b9ee1c","volume":"38","author":"K Okazaki","year":"2009","unstructured":"Okazaki K, Kawa S, Kamisawa T et al (2009) Japanese clinical guidelines for autoimmune pancreatitis. Pancreas 38:849\u2013866","journal-title":"Pancreas"},{"key":"8214_CR33","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s00535-009-0184-x","volume":"45","author":"K Okazaki","year":"2010","unstructured":"Okazaki K, Kawa S, Kamisawa T et al (2010) Japanese consensus guidelines for management of autoimmune pancreatitis: I. Concept and diagnosis of autoimmune pancreatitis. J Gastroenterol 45:249\u2013265","journal-title":"J Gastroenterol"},{"key":"8214_CR34","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/s00535-010-0221-9","volume":"45","author":"T Kamisawa","year":"2010","unstructured":"Kamisawa T, Okazaki K, Kawa S et al (2010) Japanese consensus guidelines for management of autoimmune pancreatitis: III. Treatment and prognosis of AIP. J Gastroenterol 45:471\u2013477","journal-title":"J Gastroenterol"},{"key":"8214_CR35","unstructured":"Okazaki K, Uchida K, Research Committee Members (2009) Proposal of the concept and diagnostic criteria of IgG4-related disease. Annual reports of research committee of intractable diseases supported by Ministry of Health, Labour and Welfare of Japan, pp 25\u201330 (in Japanese)"},{"key":"8214_CR36","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.3899\/jrheum.091153","volume":"37","author":"Y Masaki","year":"2010","unstructured":"Masaki Y, Sugai S, Umehara H (2010) IgG4-related diseases including Mikulicz\u2019s disease and sclerosing pancreatitis: diagnostic insights. J Rheumatol 37:1380\u20131385","journal-title":"J Rheumatol"},{"key":"8214_CR37","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1053\/gast.2002.33022","volume":"122","author":"S Kawa","year":"2002","unstructured":"Kawa S, Ota M, Yoshizawa K et al (2002) HLA DRB10405-DQB10401 haplotype is associated with autoimmune pancreatitis in the Japanese population. Gastroenterology 122:1264\u20131269","journal-title":"Gastroenterology"},{"key":"8214_CR38","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1053\/j.gastro.2007.11.023","volume":"134","author":"H Park do","year":"2008","unstructured":"Park do H, Kim MH, Oh HB (2008) Substitution of aspartic acid at position 57 of the DQbeta1 affects relapse of autoimmune pancreatitis. Gastroenterology 134:440\u2013446","journal-title":"Gastroenterology"},{"issue":"5","key":"8214_CR39","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1038\/ng1540","volume":"37","author":"Y Kochi","year":"2005","unstructured":"Kochi Y, Yamada R, Suzuki A et al (2005) A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities. Nat Genet 37(5):478\u2013485","journal-title":"Nat Genet"},{"issue":"9","key":"8214_CR40","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1136\/gut.2006.095059","volume":"55","author":"T Umemura","year":"2006","unstructured":"Umemura T, Ota M, Hamano H, Katsuyama Y, Kiyosawa K, Kawa S (2006) Genetic association of Fc receptor-like 3 polymorphisms with autoimmune pancreatitis in Japanese patients. Gut 55(9):1367\u20131368","journal-title":"Gut"},{"key":"8214_CR41","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1016\/j.humimm.2009.05.009","volume":"70","author":"T Umemura","year":"2009","unstructured":"Umemura T, Katsuyama Y, Hamano H et al (2009) Association analysis of Toll-like receptor 4 polymorphisms with autoimmune pancreatitis. Hum Immunol 70:742\u2013746","journal-title":"Hum Immunol"},{"issue":"9","key":"8214_CR42","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1373\/clinchem.2007.085951","volume":"53","author":"MC Chang","year":"2007","unstructured":"Chang MC, Chang YT, Tien YW et al (2007) T-cell regulatory gene CTLA-4 polymorphism\/haplotype association with autoimmune pancreatitis. Clin Chem 53(9):1700\u20131705","journal-title":"Clin Chem"},{"issue":"3","key":"8214_CR43","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1111\/j.1572-0241.2007.01750.x","volume":"103","author":"T Umemura","year":"2008","unstructured":"Umemura T, Ota M, Hamano H et al (2008) Association of autoimmune pancreatitis with cytotoxic T-lymphocyte antigen 4 gene polymorphisms in Japanese patients. Am J Gastroenterol 103(3):588\u2013594","journal-title":"Am J Gastroenterol"},{"issue":"6939","key":"8214_CR44","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1038\/nature01621","volume":"423","author":"H Ueda","year":"2003","unstructured":"Ueda H, Howson JM, Esposito L et al (2003) Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 423(6939):506\u2013511","journal-title":"Nature"},{"key":"8214_CR45","first-page":"43","volume-title":"Roitt\u2019s essential immunology","author":"I Roitt","year":"1997","unstructured":"Roitt I (1997) Antibodies. In: Roitt I (ed) Roitt\u2019s essential immunology, 9th edn. Blackwell Science, London, pp 43\u201362","edition":"9"},{"key":"8214_CR46","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1007\/s00535-009-0106-y","volume":"44","author":"M Taguchi","year":"2009","unstructured":"Taguchi M, Kihara Y, Nagashio Y, Yamamoto M, Otsuki M, Harada M (2009) Decreased production of immunoglobulin M and A in autoimmune pancreatitis. J Gastroenterol 44:1133\u20131139","journal-title":"J Gastroenterol"},{"issue":"10","key":"8214_CR47","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1172\/JCI200423595","volume":"114","author":"DS Robinson","year":"2004","unstructured":"Robinson DS, Larche M, Durham SR (2004) Tregs and allergic disease. J Clin Invest 114(10):1389\u20131397","journal-title":"J Clin Invest"},{"issue":"5844","key":"8214_CR48","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1126\/science.1144603","volume":"317","author":"M Neut Kolfschoten van der","year":"2007","unstructured":"van der Neut Kolfschoten M, Schuurman J, Losen M et al (2007) Anti-inflammatory activity of human IgG4 antibodies by dynamic Fab arm exchange. Science 317(5844):1554\u20131557","journal-title":"Science"},{"issue":"2","key":"8214_CR49","doi-asserted-by":"crossref","first-page":"e1637","DOI":"10.1371\/journal.pone.0001637","volume":"3","author":"S Kawa","year":"2008","unstructured":"Kawa S, Kitahara K, Hamano H et al (2008) A novel immunoglobulin-immunoglobulin interaction in autoimmunity. PLoS ONE 3(2):e1637","journal-title":"PLoS ONE"},{"issue":"10","key":"8214_CR50","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1097\/PAS.0b013e318059b87c","volume":"31","author":"LD Cornell","year":"2007","unstructured":"Cornell LD, Chicano SL, Deshpande V et al (2007) Pseudotumors due to IgG4 immune-complex tubulointerstitial nephritis associated with autoimmune pancreatocentric disease. Am J Surg Pathol 31(10):1586\u20131597","journal-title":"Am J Surg Pathol"},{"issue":"1","key":"8214_CR51","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1097\/01.mpa.0000188308.75043.e4","volume":"32","author":"T Muraki","year":"2006","unstructured":"Muraki T, Hamano H, Ochi Y et al (2006) Autoimmune pancreatitis and complement activation system. Pancreas 32(1):16\u201321","journal-title":"Pancreas"},{"issue":"10","key":"8214_CR52","doi-asserted-by":"crossref","first-page":"2788","DOI":"10.1111\/j.1572-0241.2000.03187.x","volume":"95","author":"K Uchida","year":"2000","unstructured":"Uchida K, Okazaki K, Konishi Y et al (2000) Clinical analysis of autoimmune-related pancreatitis. Am J Gastroenterol 95(10):2788\u20132794","journal-title":"Am J Gastroenterol"},{"issue":"3","key":"8214_CR53","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/S0016-5085(00)70264-2","volume":"118","author":"K Okazaki","year":"2000","unstructured":"Okazaki K, Uchida K, Ohana M et al (2000) Autoimmune-related pancreatitis is associated with autoantibodies and a Th1\/Th2-type cellular immune response. Gastroenterology 118(3):573\u2013581","journal-title":"Gastroenterology"},{"issue":"4","key":"8214_CR54","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1093\/ndt\/gfl672","volume":"22","author":"H Nishi","year":"2007","unstructured":"Nishi H, Tojo A, Onozato ML et al (2007) Anti-carbonic anhydrase II antibody in autoimmune pancreatitis and tubulointerstitial nephritis. Nephrol Dial Transplant 22(4):1273\u20131275","journal-title":"Nephrol Dial Transplant"},{"issue":"5","key":"8214_CR55","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1136\/gut.2004.047142","volume":"54","author":"L Aparisi","year":"2005","unstructured":"Aparisi L, Farre A, Gomez-Cambronero L et al (2005) Antibodies to carbonic anhydrase and IgG4 levels in idiopathic chronic pancreatitis: relevance for diagnosis of autoimmune pancreatitis. Gut 54(5):703\u2013709","journal-title":"Gut"},{"issue":"2","key":"8214_CR56","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1136\/gut.2004.049064","volume":"54","author":"I Nishimori","year":"2005","unstructured":"Nishimori I, Miyaji E, Morimoto K, Nagao K, Kamada M, Onishi S (2005) Serum antibodies to carbonic anhydrase IV in patients with autoimmune pancreatitis. Gut 54(2):274\u2013281","journal-title":"Gut"},{"issue":"1","key":"8214_CR57","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1097\/01.mpa.0000226881.48204.fd","volume":"33","author":"M Asada","year":"2006","unstructured":"Asada M, Nishio A, Uchida K et al (2006) Identification of a novel autoantibody against pancreatic secretory trypsin inhibitor in patients with autoimmune pancreatitis. Pancreas 33(1):20\u201326","journal-title":"Pancreas"},{"issue":"3","key":"8214_CR58","doi-asserted-by":"crossref","first-page":"732","DOI":"10.2337\/db08-0493","volume":"58","author":"T Endo","year":"2009","unstructured":"Endo T, Takizawa S, Tanaka S et al (2009) Amylase alpha-2A autoantibodies: novel marker of autoimmune pancreatitis and fulminant type 1 diabetes. Diabetes 58(3):732\u2013737","journal-title":"Diabetes"},{"issue":"1","key":"8214_CR59","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.bbrc.2009.06.009","volume":"386","author":"S Takizawa","year":"2009","unstructured":"Takizawa S, Endo T, Wanjia X, Tanaka S, Takahashi M, Kobayashi T (2009) HSP 10 is a new autoantigen in both autoimmune pancreatitis and fulminant type 1 diabetes. Biochem Biophys Res Commun 386(1):192\u2013196","journal-title":"Biochem Biophys Res Commun"},{"issue":"22","key":"8214_CR60","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1056\/NEJMoa0903068","volume":"361","author":"L Frulloni","year":"2009","unstructured":"Frulloni L, Lunardi C, Simone R et al (2009) Identification of a novel antibody associated with autoimmune pancreatitis. N Engl J Med 361(22):2135\u20132142","journal-title":"N Engl J Med"},{"issue":"9","key":"8214_CR61","doi-asserted-by":"crossref","first-page":"4865","DOI":"10.4049\/jimmunol.154.9.4865","volume":"154","author":"I Nishimori","year":"1995","unstructured":"Nishimori I, Bratanova T, Toshkov I et al (1995) Induction of experimental autoimmune sialoadenitis by immunization of PL\/J mice with carbonic anhydrase II. J Immunol 154(9):4865\u20134873","journal-title":"J Immunol"},{"issue":"5","key":"8214_CR62","first-page":"629","volume":"78","author":"Y Ueno","year":"1998","unstructured":"Ueno Y, Ishii M, Takahashi S, Igarashi T, Toyota T, LaRusso NF (1998) Different susceptibility of mice to immune-mediated cholangitis induced by immunization with carbonic anhydrase II. Lab Invest 78(5):629\u2013637","journal-title":"Lab Invest"},{"issue":"1","key":"8214_CR63","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1053\/j.gastro.2007.05.044","volume":"133","author":"J Kountouras","year":"2007","unstructured":"Kountouras J, Zavos C, Gavalas E, Tzilves D (2007) Challenge in the pathogenesis of autoimmune pancreatitis: potential role of helicobacter pylori infection via molecular mimicry. Gastroenterology 133(1):368\u2013369","journal-title":"Gastroenterology"},{"issue":"1","key":"8214_CR64","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1111\/j.1582-4934.2005.tb00349.x","volume":"9","author":"J Kountouras","year":"2005","unstructured":"Kountouras J, Zavos C, Chatzopoulos D (2005) A concept on the role of Helicobacter pylori infection in autoimmune pancreatitis. J Cell Mol Med 9(1):196\u2013207","journal-title":"J Cell Mol Med"},{"issue":"3","key":"8214_CR65","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1111\/j.1582-4934.2005.tb00506.x","volume":"9","author":"F Guarneri","year":"2005","unstructured":"Guarneri F, Guarneri C, Benvenga S (2005) Helicobacter pylori and autoimmune pancreatitis: role of carbonic anhydrase via molecular mimicry? J Cell Mol Med 9(3):741\u2013744","journal-title":"J Cell Mol Med"},{"issue":"6","key":"8214_CR66","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.smim.2007.10.012","volume":"19","author":"MJ McGeachy","year":"2007","unstructured":"McGeachy MJ, Cua DJ (2007) The link between IL-23 and Th17 cell-mediated immune pathologies. Semin Immunol 19(6):372\u2013376","journal-title":"Semin Immunol"},{"issue":"Suppl 3","key":"8214_CR67","doi-asserted-by":"crossref","first-page":"iii87","DOI":"10.1136\/ard.2007.078527","volume":"66","author":"M Oukka","year":"2007","unstructured":"Oukka M (2007) Interplay between pathogenic Th17 and regulatory T cells. Ann Rheum Dis 66(Suppl 3):iii87\u2013iii90","journal-title":"Ann Rheum Dis"},{"issue":"2","key":"8214_CR68","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1093\/rheumatology\/keh447","volume":"44","author":"M Yamamoto","year":"2005","unstructured":"Yamamoto M, Harada S, Ohara M et al (2005) Clinical and pathological differences between Mikulicz\u2019s disease and Sjogren\u2019s syndrome. Rheumatology 44(2):227\u2013234","journal-title":"Rheumatology"},{"issue":"6","key":"8214_CR69","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1002\/hep.21697","volume":"45","author":"Y Zen","year":"2007","unstructured":"Zen Y, Fujii T, Harada K et al (2007) Th2 and regulatory immune reactions are increased in immunoglobulin G4-related sclerosing pancreatitis and cholangitis. Hepatology 45(6):1538\u20131546","journal-title":"Hepatology"},{"issue":"4","key":"8214_CR70","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/labinvest.3780435","volume":"82","author":"K Uchida","year":"2002","unstructured":"Uchida K, Okazaki K, Nishi T et al (2002) Experimental immune-mediated pancreatitis in neonatally thymectomized mice immunized with carbonic anhydrase II and lactoferrin. Lab Invest 82(4):411\u2013424","journal-title":"Lab Invest"},{"issue":"2","key":"8214_CR71","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1093\/rheumatology\/37.2.179","volume":"37","author":"RA Ajjan","year":"1998","unstructured":"Ajjan RA, McIntosh RS, Waterman EA et al (1998) Analysis of the T-cell receptor Valpha repertoire and cytokine gene expression in Sjogren\u2019s syndrome. Br J Rheumatol 37(2):179\u2013185","journal-title":"Br J Rheumatol"},{"issue":"2","key":"8214_CR72","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s004280050077","volume":"431","author":"HP Dienes","year":"1997","unstructured":"Dienes HP, Lohse AW, Gerken G et al (1997) Bile duct epithelia as target cells in primary biliary cirrhosis and primary sclerosing cholangitis. Virchows Arch 431(2):119\u2013124","journal-title":"Virchows Arch"},{"issue":"11","key":"8214_CR73","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1038\/ncprheum0624","volume":"3","author":"X Valencia","year":"2007","unstructured":"Valencia X, Lipsky PE (2007) CD4+CD25+FoxP3+ regulatory T cells in autoimmune diseases. Nat Clin Pract Rheumatol 3(11):619\u2013626","journal-title":"Nat Clin Pract Rheumatol"},{"issue":"3","key":"8214_CR74","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.jaut.2005.01.015","volume":"24","author":"JE Gottenberg","year":"2005","unstructured":"Gottenberg JE, Lavie F, Abbed K et al (2005) CD4 CD25high regulatory T cells are not impaired in patients with primary Sjogren\u2019s syndrome. J Autoimmun 24(3):235\u2013242","journal-title":"J Autoimmun"},{"issue":"2","key":"8214_CR75","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1097\/MPA.0b013e3181577553","volume":"36","author":"H Miyoshi","year":"2008","unstructured":"Miyoshi H, Uchida K, Taniguchi T et al (2008) Circulating naive and CD4+CD25high regulatory T cells in patients with autoimmune pancreatitis. Pancreas 36(2):133\u2013140","journal-title":"Pancreas"},{"issue":"17","key":"8214_CR76","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1056\/NEJMra061111","volume":"355","author":"JR Stanley","year":"2006","unstructured":"Stanley JR, Amagai M (2006) Pemphigus, bullous impetigo, and the staphylococcal scalded-skin syndrome. N Engl J Med 355(17):1800\u20131810","journal-title":"N Engl J Med"},{"issue":"5","key":"8214_CR77","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1046\/j.1523-1755.2003.00252.x","volume":"64","author":"H Fujii","year":"2003","unstructured":"Fujii H, Nakatani K, Arita N et al (2003) Internalization of antibodies by endothelial cells via fibronectin implicating a novel mechanism in lupus nephritis. Kidney Int 64(5):1662\u20131670","journal-title":"Kidney Int"},{"issue":"4","key":"8214_CR78","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1365-2222.2009.03207.x","volume":"39","author":"RC Aalberse","year":"2009","unstructured":"Aalberse RC, Stapel SO, Schuurman J, Rispens T (2009) Immunoglobulin G4: an odd antibody. Clin Exp Allergy 39(4):469\u2013477","journal-title":"Clin Exp Allergy"},{"issue":"7","key":"8214_CR79","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1111\/j.1365-2222.2007.02749.x","volume":"37","author":"B Ruiter","year":"2007","unstructured":"Ruiter B, Knol EF, van Neerven RJ et al (2007) Maintenance of tolerance to cow\u2019s milk in atopic individuals is characterized by high levels of specific immunoglobulin G4. Clin Exp Allergy 37(7):1103\u20131110","journal-title":"Clin Exp Allergy"},{"issue":"9","key":"8214_CR80","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.4049\/jimmunol.148.9.2731","volume":"148","author":"R Hussain","year":"1992","unstructured":"Hussain R, Poindexter RW, Ottesen EA (1992) Control of allergic reactivity in human filariasis. Predominant localization of blocking antibody to the IgG4 subclass. J Immunol 148(9):2731\u20132737","journal-title":"J Immunol"},{"issue":"7","key":"8214_CR81","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/S1471-4906(01)01958-5","volume":"22","author":"M Yazdanbakhsh","year":"2001","unstructured":"Yazdanbakhsh M, van den Biggelaar A, Maizels RM (2001) Th2 responses without atopy: immunoregulation in chronic helminth infections and reduced allergic disease. Trends Immunol 22(7):372\u2013377","journal-title":"Trends Immunol"},{"issue":"1","key":"8214_CR82","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1084\/jem.161.1.72","volume":"161","author":"S Sakaguchi","year":"1985","unstructured":"Sakaguchi S, Fukuma K, Kuribayashi K, Masuda T (1985) Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease. J Exp Med 161(1):72\u201387","journal-title":"J Exp Med"},{"issue":"3","key":"8214_CR83","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/S0016-5085(00)70265-4","volume":"118","author":"A Demols","year":"2000","unstructured":"Demols A, Le Moine O, Desalle F, Quertinmont E, Van Laethem JL, Deviere J (2000) CD4(+)T cells play an important role in acute experimental pancreatitis in mice. Gastroenterology 118(3):582\u2013590","journal-title":"Gastroenterology"},{"issue":"4","key":"8214_CR84","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1016\/S0016-5085(98)70270-7","volume":"115","author":"BA Vallance","year":"1998","unstructured":"Vallance BA, Hewlett BR, Snider DP, Collins SM (1998) T cell-mediated exocrine pancreatic damage in major histocompatibility complex class II-deficient mice. Gastroenterology 115(4):978\u2013987","journal-title":"Gastroenterology"},{"issue":"1","key":"8214_CR85","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-2249.2008.03588.x","volume":"152","author":"Y Sakaguchi","year":"2008","unstructured":"Sakaguchi Y, Inaba M, Tsuda M et al (2008) The Wistar Bonn Kobori rat, a unique animal model for autoimmune pancreatitis with extrapancreatic exocrinopathy. Clin Exp Immunol 152(1):1\u201312","journal-title":"Clin Exp Immunol"},{"issue":"6","key":"8214_CR86","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.4049\/jimmunol.157.6.2348","volume":"157","author":"T Marth","year":"1996","unstructured":"Marth T, Strober W, Kelsall BL (1996) High dose oral tolerance in ovalbumin TCR-transgenic mice: systemic neutralization of IL-12 augments TGF-beta secretion and T cell apoptosis. J Immunol 157(6):2348\u20132357","journal-title":"J Immunol"},{"issue":"8","key":"8214_CR87","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1172\/JCI8337","volume":"105","author":"KB Hahm","year":"2000","unstructured":"Hahm KB, Im YH, Lee C et al (2000) Loss of TGF-beta signaling contributes to autoimmune pancreatitis. J Clin Invest 105(8):1057\u20131065","journal-title":"J Clin Invest"},{"issue":"23","key":"8214_CR88","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.2169\/internalmedicine.49.4165","volume":"49","author":"T Kusuda","year":"2010","unstructured":"Kusuda T, Uchida K, Satoi S et al (2010) Idiopathic duct-centric pancreatitis (IDCP) with immunological studies. Intern Med 49(23):2569\u20132575","journal-title":"Intern Med"}],"container-title":["Clinical Reviews in Allergy & Immunology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12016-010-8214-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12016-010-8214-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12016-010-8214-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,4]],"date-time":"2023-06-04T14:46:02Z","timestamp":1685889962000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12016-010-8214-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,12,18]]},"references-count":88,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,10]]}},"alternative-id":["8214"],"URL":"https:\/\/doi.org\/10.1007\/s12016-010-8214-2","relation":{},"ISSN":["1080-0549","1559-0267"],"issn-type":[{"value":"1080-0549","type":"print"},{"value":"1559-0267","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,12,18]]}}}