{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T20:56:45Z","timestamp":1778273805417,"version":"3.51.4"},"reference-count":74,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2011,1,8]],"date-time":"2011-01-08T00:00:00Z","timestamp":1294444800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinic Rev Allerg Immunol"],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1007\/s12016-010-8240-0","type":"journal-article","created":{"date-parts":[[2011,1,7]],"date-time":"2011-01-07T04:50:16Z","timestamp":1294375816000},"page":"172-180","source":"Crossref","is-referenced-by-count":9,"title":["The Clinical Significance of Coagulation and the Inflammatory Response in Autoimmunity"],"prefix":"10.1007","volume":"42","author":[{"given":"Benjam\u00edn","family":"Rubio-Jurado","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulina","family":"I\u00f1iguez-Franco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro A.","family":"Reyes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo","family":"Robles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Salazar-P\u00e1ramo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guadalupe","family":"Zavala-Cerna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Riebeling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnulfo","family":"Nava","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,1,8]]},"reference":[{"key":"8240_CR1","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1182\/blood.V91.4.1140","volume":"91","author":"D Williamson","year":"1998","unstructured":"Williamson D, Brown K, Luddington R, Baglin C, Baglin T (1998) Factor V Cambridge: a new mutation (Arg306-->Thr) associated with resistance to activated protein C. Blood 91:1140\u20131144","journal-title":"Blood"},{"key":"8240_CR2","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S1577-3566(05)74496-1","volume":"6","author":"MR Guti\u00e9rrez-Tous","year":"2005","unstructured":"Guti\u00e9rrez-Tous MR (2005) Trombofilia, \u00bfcu\u00e1ndo, qu\u00e9 pruebas y a qui\u00e9n? Sem Fund Esp Reumatol 6:133\u2013143","journal-title":"Sem Fund Esp Reumatol"},{"key":"8240_CR3","first-page":"1095","volume":"87","author":"V Stefano De","year":"2002","unstructured":"De Stefano V, Rossi E, Paciaroni K, Leone G (2002) Screening for inherited thrombophilia: indications and therapeutic implications. Haematologica 87:1095\u20131108","journal-title":"Haematologica"},{"key":"8240_CR4","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/S0140-6736(05)71880-8","volume":"365","author":"S Eichinger","year":"2005","unstructured":"Eichinger S (2005) Deep vein thrombosis. Lancet 365:1163\u20131174","journal-title":"Lancet"},{"key":"8240_CR5","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1055\/s-2005-863803","volume":"31","author":"M Hertzberg","year":"2005","unstructured":"Hertzberg M (2005) Genetic testing for thrombophilia mutations. Sem Thromb Hemost 31:33\u201338","journal-title":"Sem Thromb Hemost"},{"key":"8240_CR6","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1182\/blood.V98.1.21","volume":"98","author":"MP Mannuccio","year":"2001","unstructured":"Mannuccio MP (2001) Genetic hypercoagulability: prevention suggests testing family members. Blood 98:21\u201322","journal-title":"Blood"},{"key":"8240_CR7","first-page":"313","volume":"75","author":"B Rubio-Jurado","year":"2007","unstructured":"Rubio-Jurado B, Salazar P\u00e1ramo M, Medrano Mu\u00f1oz F, Gonz\u00e1lez-Ojeda A, Nava A (2007) Trombofilia, Autoinmunidad Y Tromboprofilaxis Postoperatoria. Cir Ciruj 75:313\u2013323","journal-title":"Cir Ciruj"},{"key":"8240_CR8","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/j.1365-2796.2004.01444.x","volume":"257","author":"B Dahlb\u00e4ck","year":"2005","unstructured":"Dahlb\u00e4ck B (2005) Blood coagulation and its regulation by anticoagulant pathways: genetic pathogenesis of bleeding and thrombotic diseases. J Intern Med 257:209\u2013223","journal-title":"J Intern Med"},{"key":"8240_CR9","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1093\/bja\/aeh174","volume":"93","author":"T Bombeli","year":"2004","unstructured":"Bombeli T, Spahn DR (2004) Updates in perioperative coagulation: physiology and management of thromboembolism and haemorrhage. Br J Anaesth 93:275\u2013287","journal-title":"Br J Anaesth"},{"issue":"1","key":"8240_CR10","first-page":"17","volume":"XVIIII","author":"ER Carrillo","year":"2004","unstructured":"Carrillo ER, Salmeron NP, Carvajal RR, Contreras DV, Hern\u00e1ndez AC (2004) Rompiendo un paradigma: del modelo humoral al modelo celular de la coagulaci\u00f3n. Su aplicaci\u00f3n cl\u00ednica en el enfermo grave. Med Crit Ter Int XVIIII(1):17\u201323","journal-title":"Med Crit Ter Int"},{"key":"8240_CR11","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1161\/01.ATV.0000130465.23430.74","volume":"24","author":"N Mackman","year":"2004","unstructured":"Mackman N (2004) Role of tissue factor in hemostasis, thrombosis, and vascular development. Arterioscler Thromb Vasc Biol 24:1015\u20131022","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"11","key":"8240_CR12","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1038\/nm1102-1227","volume":"8","author":"ZM Ruggeri","year":"2002","unstructured":"Ruggeri ZM (2002) Platelets in atherothrombosis. Nat Med 8(11):1227\u20131234","journal-title":"Nat Med"},{"key":"8240_CR13","doi-asserted-by":"crossref","first-page":"42887","DOI":"10.1074\/jbc.M505506200","volume":"280","author":"T Orfeo","year":"2005","unstructured":"Orfeo T, Butenas S, Brummel-Ziedins KE, Man K (2005) The tissue factor requirement in blood coagulation. J Biol Chem 280:42887\u201342896","journal-title":"J Biol Chem"},{"issue":"8","key":"8240_CR14","first-page":"267","volume":"62","author":"PG Groot de","year":"2004","unstructured":"de Groot PG, Derksen RH (2004) Pathophysiology of antiphospholipid antibodies. Neth J Med 62(8):267\u2013272","journal-title":"Neth J Med"},{"key":"8240_CR15","doi-asserted-by":"crossref","first-page":"3598","DOI":"10.1182\/blood-2004-03-1107","volume":"104","author":"H Bas de Laat","year":"2004","unstructured":"Bas de Laat H, Derksen RH, Urbanus RT, Roest M, de Groot PG (2004) \u00df2-glycoprotein I-dependent lupus anticoagulant highly correlates with thrombosis in the antiphospholipid syndrome. Blood 104:3598\u20133602","journal-title":"Blood"},{"key":"8240_CR16","first-page":"699","volume":"91","author":"J Nojima","year":"2006","unstructured":"Nojima J, Iwatani Y, Suehisa E, Kuratsune H, Kanakura Y (2006) The presence of anti-phosphatidylserine\/prothrombin antibodies as risk factor for both arterial and venous thrombosis in patients with systemic lupus erythematous. Hematologica 91:699\u2013702","journal-title":"Hematologica"},{"key":"8240_CR17","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s11239-006-5581-x","volume":"21","author":"L Ortel Thomas","year":"2006","unstructured":"Ortel Thomas L (2006) The syndrome antiphospholipid: what are we really measuring? How do we measure it? And how do we treat it? J Thromb Thrombolysis 21:79\u201383","journal-title":"J Thromb Thrombolysis"},{"key":"8240_CR18","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.imbio.2007.01.001","volume":"212","author":"B Salobir","year":"2007","unstructured":"Salobir B, Sabovic M, Hojnikc M, Cucnikc S, Kveder T (2007) Anti-b2-glycoprotein I antibodies of IgM class are linked to thrombotic disorders in young women without autoimmune disease. Immunobiology 212:193\u2013199","journal-title":"Immunobiology"},{"key":"8240_CR19","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1182\/blood-2006-04-001206","volume":"109","author":"B Giannakopoulos","year":"2007","unstructured":"Giannakopoulos B, Passam F, Rahgoza SA, Krilis S (2007) Current concepts on the pathogenesis of the antiphospholipid syndrome. Blood 109:422\u2013430","journal-title":"Blood"},{"key":"8240_CR20","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.blre.2007.09.001","volume":"22","author":"RT Urbanus","year":"2008","unstructured":"Urbanus RT, Derksen R, de Groot PG (2008) Current insight into diagnostics and pathophysiology of the antiphospolipid syndrome. Blood Rev 22:93\u2013105","journal-title":"Blood Rev"},{"key":"8240_CR21","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1111\/j.1538-7836.2005.01359.x","volume":"3","author":"PG Groot de","year":"2007","unstructured":"de Groot PG, Derksen RH (2007) Pathophysiology of the antiphospholipid syndrome. J Thromb Haemost 3:1854\u20131860","journal-title":"J Thromb Haemost"},{"key":"8240_CR22","first-page":"366","volume":"13","author":"S Pierangeli","year":"2006","unstructured":"Pierangeli S, Chen PP, Gonz\u00e1lez EB (2006) Antiphospholipid antibodies and the antiphospholipid syndrome:an update on treatment and pathogenic mechanisms. Curr Opin Hematol 13:366\u2013375","journal-title":"Curr Opin Hematol"},{"key":"8240_CR23","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1055\/s-0028-1082267","volume":"34","author":"SS Pierangeli","year":"2008","unstructured":"Pierangeli SS, Chen PP, Raschi E, Scurati S, Grossi C, Borghi MA, Palomo I, Harris N, Meroni PL (2008) Antiphospholipid antibodies and the antiphospholipid syndrome: pathogenic mechanisms. Semin Thromb Hemost 34:236\u2013250","journal-title":"Semin Thromb Hemost"},{"issue":"4","key":"8240_CR24","first-page":"192","volume":"4","author":"B Laat de","year":"2008","unstructured":"de Laat B, Mertens K, de Groot PG (2008) Mechanisms of disease: antiphospholipid antibodies\u2014from clinical association to pathologic mechanism. Nature clinical practice. Rheumatology 4(4):192\u2013199","journal-title":"Rheumatology"},{"key":"8240_CR25","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1055\/s-0028-1085475","volume":"34","author":"K Oku","year":"2008","unstructured":"Oku K, Atsumi T, Amengual O, Koike T (2008) Antiprothrombin antibody testing: detection and clinical utility. Semin Thromb Hemost 34:335\u2013339","journal-title":"Semin Thromb Hemost"},{"key":"8240_CR26","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1002\/ajh.20124","volume":"76","author":"K Ishikura","year":"2004","unstructured":"Ishikura K, Wada H, Kamikura Y, Hattori K, Fukuzawa T, Yamada N, Nakamura M, Nobori T, Nakano T (2004) High prevalence of anti-prothrombin antibody in patients with deep vein thrombosis. Am J Hematol 76:338\u2013342","journal-title":"Am J Hematol"},{"key":"8240_CR27","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1136\/ard.2005.035824","volume":"64","author":"M Bertolaccini","year":"2005","unstructured":"Bertolaccini M, Gomez S, Pareja JF, Theodoridou A, Sanna G, Hughes GRV, Khamashta MA (2005) Antiphospholipid antibody tests: spreading the net. Ann Rheum Dis 64:1639\u20131643","journal-title":"Ann Rheum Dis"},{"issue":"4","key":"8240_CR28","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1002\/art.10831","volume":"48","author":"O Amengual","year":"2003","unstructured":"Amengual O, Atsumi T, Koike T (2003) Specificities, properties, and clinical significance of antiprothrombin antibodies. Arthritis Rheum 48(4):886\u2013895","journal-title":"Arthritis Rheum"},{"key":"8240_CR29","doi-asserted-by":"crossref","first-page":"3378","DOI":"10.1172\/JCI27196","volume":"115","author":"M Gawaz","year":"2005","unstructured":"Gawaz M, Langer H, May AE (2005) Platelets in inflammation and atherogenesis. J Clin Invest 115:3378\u20133384","journal-title":"J Clin Invest"},{"issue":"7","key":"8240_CR30","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1111\/j.1582-4934.2009.00811.x","volume":"13","author":"HF Langer","year":"2009","unstructured":"Langer HF, Chavakis T (2009) Leukocyte-endothelial interactions in inflammation. J Cell Mol Med 13(7):1211\u20131220, Epub 2009 Jun 16. Review. PubMed PMID:19538472; PubMed Central PMCID: PMC2861890)","journal-title":"J Cell Mol Med"},{"issue":"3","key":"8240_CR31","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S1043-4682(10)80017-0","volume":"3","author":"D Vestweber","year":"1992","unstructured":"Vestweber D (1992) Selectins: cell surface lectins which mediate the binding of leukocytes to endothelial cells. Semin Cell Biol 3(3):211\u2013220, Review. PubMed PMID: 1623209","journal-title":"Semin Cell Biol"},{"issue":"1","key":"8240_CR32","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0092-8674(92)90115-S","volume":"69","author":"RO Hynes","year":"1992","unstructured":"Hynes RO (1992) Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69(1):11\u201325, Review. PubMed PMID: 1555235","journal-title":"Cell"},{"issue":"2","key":"8240_CR33","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1042\/bst0300168","volume":"30","author":"T Chavakis","year":"2002","unstructured":"Chavakis T, Kanse SM, May AE, Preissner KT (2002) Haemostatic factors occupy new territory: the role of the urokinase receptor system and kininogen in inflammation. Biochem Soc Trans 30(2):168\u2013173, Review. PubMed PMID: 12023845","journal-title":"Biochem Soc Trans"},{"key":"8240_CR34","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1146\/annurev.ph.57.030195.004143","volume":"57","author":"TA Springer","year":"1995","unstructured":"Springer TA (1995) Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration. Annu Rev Physiol 57:827\u2013872, Review. PubMed PMID:7778885","journal-title":"Annu Rev Physiol"},{"issue":"2","key":"8240_CR35","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1160\/TH07-03-0206","volume":"98","author":"VV Orlova","year":"2007","unstructured":"Orlova VV, Chavakis T (2007) Regulation of vascular endothelial permeability by junctional adhesion molecules (JAM). Thromb Haemost 98(2):327\u2013332, PubMed PMID: 17721614)","journal-title":"Thromb Haemost"},{"key":"8240_CR36","first-page":"71","volume":"632","author":"U Amara","year":"2008","unstructured":"Amara U, Rittirsch D, Flierl M, Bruckner U, Klos A, Gebhard F, Lambris JD, Huber-Lang M (2008) Interaction between the coagulation and complement system. Adv Exp Med Biol 632:71\u201379, Review. PubMed PMID: 19025115; PubMed Central PMCID:PMC2713875","journal-title":"Adv Exp Med Biol"},{"issue":"4","key":"8240_CR37","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1007\/s004230100242","volume":"386","author":"C Hierholzer","year":"2001","unstructured":"Hierholzer C, Billiar TR (2001) Molecular mechanisms in the early phase of hemorrhagic shock. Langenbecks Arch Surg 386(4):302\u2013308, Review. PubMed PMID: 11466573","journal-title":"Langenbecks Arch Surg"},{"issue":"7","key":"8240_CR38","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1358\/dnp.2004.17.7.863703","volume":"17","author":"AE Davis 3rd","year":"2004","unstructured":"Davis AE 3rd (2004) Biological effects of C1 inhibitor. Drug News Perspect 17(7):439\u2013446, Review. PubMed PMID: 15514703","journal-title":"Drug News Perspect"},{"issue":"6","key":"8240_CR39","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1038\/nm1419","volume":"12","author":"M Huber-Lang","year":"2006","unstructured":"Huber-Lang M, Sarma JV, Zetoune FS, Rittirsch D, Neff TA, McGuire SR, Lambris JD, Warner RL, Flierl MA, Hoesel LM, Gebhard F, Younger JG, Drouin SM, Wetsel RA, Ward PA (2006) Generation of C5a in the absence of C3: a new complement activation pathway. Nat Med 12(6):682\u2013687, Epub 2006 May 21. PubMed PMID: 16715088","journal-title":"Nat Med"},{"key":"8240_CR40","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1161\/01.RES.0000252802.25497.b7","volume":"100","author":"P Hundelshausen von","year":"2007","unstructured":"von Hundelshausen P, Weber C (2007) Platelets as immune cells: bridging inflammation and cardiovascular disease. Circ Res 100:27\u201340","journal-title":"Circ Res"},{"issue":"21","key":"8240_CR41","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1038\/nature06797","volume":"451","author":"N Mackman","year":"2008","unstructured":"Mackman N (2008) Triggers, targets and treatments for thrombosis. Nature 451(21):914\u2013918","journal-title":"Nature"},{"issue":"1","key":"8240_CR42","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1055\/s-2008-1066020","volume":"43","author":"M Levi","year":"2008","unstructured":"Levi M, Nieuwdorp M, van der Poll T, Stroes E (2008) Metabolic modulation of inflammation-induced activation of coagulation. Sem Thromb Hemost 43(1):26\u201332","journal-title":"Sem Thromb Hemost"},{"key":"8240_CR43","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1191\/0961203305lu2210oa","volume":"14","author":"G Liuzzo","year":"2005","unstructured":"Liuzzo G, Giubilato G, Pinnelli M (2005) T cells and cytokines in atherogenesis. Lupus 14:732\u2013735","journal-title":"Lupus"},{"key":"8240_CR44","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1161\/01.ATV.0000174800.78362.ec","volume":"25","author":"J Frosteg\u00e5rd","year":"2005","unstructured":"Frosteg\u00e5rd J (2005) Atherosclerosis in patients with autoimmune disorders. Arterioscler Thromb Vasc Biol 25:1776\u20131785","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"8240_CR45","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1038\/nri1882","volume":"6","author":"GK Hansson","year":"2006","unstructured":"Hansson GK, Libby P (2006) The immune response in atherosclerosis: a double-edged sword. Nat Rev Immunol 6:508\u2013519","journal-title":"Nat Rev Immunol"},{"key":"8240_CR46","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1196\/annals.1361.073","volume":"1051","author":"LR Lopez","year":"2005","unstructured":"Lopez LR, Simpson DF, Hurley BL, Matsuura E (2005) OxLDL\/beta2GPI complexes and autoantibodies in patients with systemic lupus erythematosus, systemic sclerosis, and antiphospholipid syndrome: pathogenic implications for vascular involvement. Ann NY Acad Sci 1051:313\u2013322, PubMed PMID: 16126973","journal-title":"Ann NY Acad Sci"},{"issue":"2","key":"8240_CR47","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1191\/0961203306lu2267oa","volume":"15","author":"LR Lopez","year":"2006","unstructured":"Lopez LR, Salazar-Paramo M, Palafox-Sanchez C, Hurley BL, Matsuura E, Garcia-De La Torre I (2006) Oxidized low-density lipoprotein and beta2-glycoprotein I in patients with systemic lupus erythematosus and increased carotid intima-media thickness: implications in autoimmune-mediated atherosclerosis. Lupus 15(2):80\u201386, PubMed PMID: 16539278","journal-title":"Lupus"},{"issue":"6","key":"8240_CR48","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.coi.2007.11.001","volume":"19","author":"M McMahon","year":"2007","unstructured":"McMahon M, Hahn BH (2007) Atherosclerosis and systemic lupus erythematosus: mechanistic basis of the association. Curr Opin Immunol 19(6):633\u2013639, Review. PubMed PMID: 18083018; PubMed Central PMCID: PMC2709458","journal-title":"Curr Opin Immunol"},{"key":"8240_CR49","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1196\/annals.1361.077","volume":"1051","author":"S Zampieri","year":"2005","unstructured":"Zampieri S, Iaccarino L, Ghirardello A, Tarricone E, Arienti S, Sarzi-Puttini P, Gambari P, Doria A (2005) Systemic lupus erythematosus, atherosclerosis, and autoantibodies. Ann NY Acad Sci 1051:351\u2013361, Review. PubMed PMID: 16126977","journal-title":"Ann NY Acad Sci"},{"issue":"4","key":"8240_CR50","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1309\/AJCP2FJUT2YZGITK","volume":"132","author":"TP Greco","year":"2009","unstructured":"Greco TP, Conti-Kelly AM, Greco T Jr, Doyle R, Matsuura E, Anthony JR, Lopez LR (2009) Newer antiphospholipid antibodies predict adverse outcomes in patients with acute coronary syndrome. Am J Clin Pathol 132(4):613\u2013620, PubMed PMID: 19762540","journal-title":"Am J Clin Pathol"},{"issue":"5","key":"8240_CR51","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1309\/AJCP88WVRDRDFBAS","volume":"133","author":"TP Greco","year":"2010","unstructured":"Greco TP, Conti-Kelly AM, Anthony JR, Greco T Jr, Doyle R, Boisen M, Kojima K, Matsuura E, Lopez LR (2010) Oxidized-LDL\/beta(2)-glycoprotein I complexes are associated with disease severity and increased risk for adverse outcomes in patients with acute coronary syndromes. Am J Clin Pathol 133(5):737\u2013743, PubMed PMID: 20395520","journal-title":"Am J Clin Pathol"},{"issue":"6","key":"8240_CR52","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.amjmed.2007.10.042","volume":"121","author":"JE Dalen","year":"2008","unstructured":"Dalen JE (2008) Should patients with venous thromboembolism be screened for thrombophilia? Am J Med 121(6):458\u2013463","journal-title":"Am J Med"},{"issue":"1","key":"8240_CR53","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0268-960X(94)90006-X","volume":"8","author":"DJ Perry","year":"1994","unstructured":"Perry DJ (1994) Antithrombin and its inherited deficiencies. Blood Rev 8(1):37\u201355","journal-title":"Blood Rev"},{"key":"8240_CR54","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1182\/blood.V85.6.1504.bloodjournal8561504","volume":"85","author":"FR Rosendaal","year":"1995","unstructured":"Rosendaal FR, Koster T, Vandenbrouke JP, Reitsma PH (1995) High risk of thrombosis in patients homozygous for factor V Leiden (activated protein C resistance). Blood 85:1504\u20131508","journal-title":"Blood"},{"issue":"S2","key":"8240_CR55","first-page":"66","volume":"139","author":"A Majluf-Cruz","year":"2003","unstructured":"Majluf-Cruz A (2003) La realidad de la prevalencia de la trombosis. Gac M\u00e9d M\u00e9x 139(S2):66\u201368","journal-title":"Gac M\u00e9d M\u00e9x"},{"key":"8240_CR56","first-page":"600","volume":"56","author":"GJ Ruiz-Arguelles","year":"2004","unstructured":"Ruiz-Arguelles GJ, Poblete-Naredo I, Reyes-Nu\u00f1ez V, Garc\u00e9s-Eisele J, Lopez Martinez B, G\u00f3mez-Rangel JD (2004) Primary thrombophilia in Mexico IV: frequency of the Leiden, Cambridge, Hong Kong, Liverpool and HR2 haplotype polymorphisms in the factor V gene of a group of thrombophilic Mexican Mestizo patients. Rev Invest Clin 56:600\u2013604","journal-title":"Rev Invest Clin"},{"key":"8240_CR57","first-page":"705","volume":"88","author":"A Tripodi","year":"2003","unstructured":"Tripodi A (2003) Levels of coagulation factors and venous thromboembolism. Hematologica 88:705\u2013711","journal-title":"Hematologica"},{"key":"8240_CR58","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1093\/ageing\/afi219","volume":"35","author":"R Mangiafico","year":"2006","unstructured":"Mangiafico R, Sarnataro F, Mangiafico M, Fiore CE (2006) Impaired cognitive performance in asymptomatic peripheral arterial disease: relation to C-reactive protein and D-dimer levels. Age Ageing 35:60\u201365","journal-title":"Age Ageing"},{"key":"8240_CR59","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1056\/NEJM199704033361401","volume":"336","author":"PM Ridker","year":"1997","unstructured":"Ridker PM, Cushman M, Stampfer MJ, Tracy RP, Hennekens CH (1997) Inflammation, aspirin, and risks of cardiovascular disease in apparently healthy men. N Engl J Med 336:973\u2013979","journal-title":"N Engl J Med"},{"issue":"5","key":"8240_CR60","first-page":"407","volume":"20","author":"JL Sepulveda","year":"2005","unstructured":"Sepulveda JL, Mehta JL (2005) C-reactive protein and cardiovascular disease: a critical appraisal. Curr Opin Cardiol 20(5):407\u2013416","journal-title":"Curr Opin Cardiol"},{"key":"8240_CR61","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0049-3848(00)00356-X","volume":"100","author":"H Tohgi","year":"2000","unstructured":"Tohgi H, Konno S, Takahashi S, Koizumi D, Kondo R, Takahashi H (2000) Activated coagulation\/fibrinolysis system and platelet function in acute thrombotic stroke patients with increased C-reactive protein levels. Thromb Res 100:373\u2013379","journal-title":"Thromb Res"},{"key":"8240_CR62","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1161\/01.STR.0000019124.54361.08","volume":"33","author":"M Napoli Di","year":"2002","unstructured":"Di Napoli M, Papa F (2002) Inflammation, hemostatic markers, and antithrombotic agents in relation to long-term risk of new cardiovascular events in first-ever ischemic stroke patients. Stroke 33:1763\u20131771","journal-title":"Stroke"},{"key":"8240_CR63","first-page":"254","volume":"84","author":"CT Esmon","year":"1999","unstructured":"Esmon CT, Fukudome K, Mather T, Bode W, Regan LM, Stearns-Kurosawa D, Kurosawa S (1999) Inflammation, sepsis, and coagulation. Haematologica 84:254\u2013259","journal-title":"Haematologica"},{"key":"8240_CR64","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1097\/00062752-200701000-00011","volume":"14","author":"K Crocea","year":"2007","unstructured":"Crocea K, Libby P (2007) Intertwining of thrombosis and inflammation in atherosclerosis. Curr Opin Hematol 14:55\u201361","journal-title":"Curr Opin Hematol"},{"key":"8240_CR65","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1177\/153857440503900201","volume":"39","author":"CM Johnson","year":"2005","unstructured":"Johnson CM, Mureebe L, Silver D (2005) Hypercoagulable states: a review. Vasc Endovasc Surg 39:123\u2013133","journal-title":"Vasc Endovasc Surg"},{"key":"8240_CR66","first-page":"64","volume":"91","author":"MM Samama","year":"2006","unstructured":"Samama MM, Dahl O, Mismetti P et al (2006) An electronic tool for venous thromboembolism prevention in medical and surgical patients. Haematologica 91:64\u201370","journal-title":"Haematologica"},{"key":"8240_CR67","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1001\/jama.295.9.1050","volume":"295","author":"W Lim","year":"2006","unstructured":"Lim W, Crowther MA, Eikelboom JW (2006) Management of antiphospholipid antibody syndrome. JAMA 295:1050\u20131057","journal-title":"JAMA"},{"key":"8240_CR68","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1056\/NEJMoa035241","volume":"349","author":"MA Crowther","year":"2003","unstructured":"Crowther MA et al (2003) A comparasion of two intensities of warfarin for the prevention of recurrent thrombosis in patients with the antiphospholipid antibody syndrome. N Eng J Med 349:1133\u20131138","journal-title":"N Eng J Med"},{"issue":"3","key":"8240_CR69","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1038\/ncprheum0432","volume":"3","author":"JE Salmon","year":"2007","unstructured":"Salmon JE, Girardi G, Lockshin MD (2007) The antiphospholipid syndrome as a disorder initiated by inflammation: implications for the therapy of pregnant patients. Nat Clin Pract Rheumatol 3(3):140\u2013147","journal-title":"Nat Clin Pract Rheumatol"},{"issue":"10","key":"8240_CR70","doi-asserted-by":"crossref","first-page":"6017","DOI":"10.4049\/jimmunol.178.10.6017","volume":"178","author":"S Danese","year":"2007","unstructured":"Danese S, Dejana E, Fiocchi C (2007) Immune regulation by microvascular endothelial cells: directing innate and adaptive immunity, coagulation, and inflammation. J Immunol 178(10):6017\u20136022, Review. PubMed PMID: 17475823","journal-title":"J Immunol"},{"issue":"10","key":"8240_CR71","first-page":"3527","volume":"91","author":"DB Cines","year":"1998","unstructured":"Cines DB, Pollak ES, Buck CA, Loscalzo J, Zimmerman GA, McEver RP, Pober JS, Wick TM, Konkle BA, Schwartz BS, Barnathan ES, McCrae KR, Hug BA, Schmidt AM, Stern DM (1998) Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood 91(10):3527\u20133561, Review. PubMed PMID: 9572988","journal-title":"Blood"},{"issue":"3","key":"8240_CR72","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1161\/01.RES.47.3.301","volume":"47","author":"H Wolinsky","year":"1980","unstructured":"Wolinsky H (1980) A proposal linking clearance of circulating lipoproteins to tissue metabolic activity as a basis for understanding atherogenesis. Circ Res 47(3):301\u2013311, Review. PubMed PMID: 6996862","journal-title":"Circ Res"},{"key":"8240_CR73","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1016\/j.amjcard.2005.06.072","volume":"96","author":"GH Tofler","year":"2005","unstructured":"Tofler GH, Massaro J, Levy D, Mittleman M, Sutherland P, Lipinska I, Muller JE, D\u2019Agostino RB (2005) Relation of the prothrombotic state to increasing age (from the Framingham Offspring Study). Am J Cardiol 96:1280\u201311283","journal-title":"Am J Cardiol"},{"issue":"1","key":"8240_CR74","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1055\/s-0037-1617146","volume":"30","author":"J Xu","year":"2010","unstructured":"Xu J, Lupu F, Esmon CT (2010) Inflammation, innate immunity and blood coagulation. Hamostaseologie 30(1):5\u20139","journal-title":"Hamostaseologie"}],"container-title":["Clinical Reviews in Allergy &amp; Immunology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12016-010-8240-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12016-010-8240-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12016-010-8240-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,4]],"date-time":"2023-06-04T19:32:15Z","timestamp":1685907135000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12016-010-8240-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1,8]]},"references-count":74,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["8240"],"URL":"https:\/\/doi.org\/10.1007\/s12016-010-8240-0","relation":{},"ISSN":["1080-0549","1559-0267"],"issn-type":[{"value":"1080-0549","type":"print"},{"value":"1559-0267","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,1,8]]}}}