{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:56:25Z","timestamp":1786982185853,"version":"build-2736575974"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2013,4,4]],"date-time":"2013-04-04T00:00:00Z","timestamp":1365033600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2013,4,4]],"date-time":"2013-04-04T00:00:00Z","timestamp":1365033600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clinic Rev Allerg Immunol"],"published-print":{"date-parts":[[2014,8]]},"DOI":"10.1007\/s12016-013-8369-8","type":"journal-article","created":{"date-parts":[[2013,4,2]],"date-time":"2013-04-02T21:17:14Z","timestamp":1364937434000},"page":"46-55","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Recommendations for the Management of Beta-Lactam Intolerance"],"prefix":"10.1007","volume":"47","author":[{"given":"Eric","family":"Macy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eunis","family":"Ngor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,4,4]]},"reference":[{"key":"8369_CR1","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/S1473-3099(12)70300-6","volume":"13","author":"P Little","year":"2013","unstructured":"Little P, Stuart B, Moore M, on behalf of the GRACE consortium et al (2013) Amoxicillin for acute lower-respiratory-tract infection in primary care when pneumonia is not suspected: a 12-country, randomised, placebo-controlled trial. Lancet Infect Dis 13:123\u2013129","journal-title":"Lancet Infect Dis"},{"key":"8369_CR2","first-page":"159","volume":"38","author":"O Idsoe","year":"1968","unstructured":"Idsoe O, Guthe T, Willcox RR, De Weck AL (1968) Nature and extent of penicillin side-reactions, with particular reference to fatalities from anaphylactic shock. Bull Wld Hlth Org 38:159\u2013188","journal-title":"Bull Wld Hlth Org"},{"key":"8369_CR3","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1016\/0021-9681(84)90004-3","volume":"37","author":"JD Clemens","year":"1984","unstructured":"Clemens JD, Ransohoff DF (1984) A quantitative assessment of pre-dental antibiotic prophylaxis for patients with metal-valve prolapse. J Chronic Dis 37:531\u2013534","journal-title":"J Chronic Dis"},{"key":"8369_CR4","doi-asserted-by":"publisher","first-page":"1172","DOI":"10.1093\/jac\/dkm315","volume":"60","author":"P Lee","year":"2007","unstructured":"Lee P, Shanson D (2007) Results of a UK survey of fatal anaphylaxis after oral amoxicillin. J Antimicrob Chemother 60:1172\u20131179","journal-title":"J Antimicrob Chemother"},{"key":"8369_CR5","doi-asserted-by":"publisher","first-page":"s364","DOI":"10.1093\/infdis\/128.Supplement_2.S364","volume":"128","author":"BB Levine","year":"1973","unstructured":"Levine BB (1973) Antigenicity and cross-reactivity of penicillins and cephalosporins. J Inf Dis 128:s364\u2013s366","journal-title":"J Inf Dis"},{"key":"8369_CR6","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1001\/archinte.1992.00400170105020","volume":"152","author":"DD Sogn","year":"1992","unstructured":"Sogn DD, Evens R III, Shepard GM, Csale TB, Codemi J, Greenberger PA, Kohler PF, Saxon A, Summers RJ, VanArsdel PP, Massicot JG, Blackwelder WC, Levine BB (1992) Results of the National Institute of Allergy and Infectious diseases collaborative clinical trial to test the predictive value of skin testing with major and minor penicillin derivatives in hospitalized adults. Arch Intern Med 152:1025\u20131032","journal-title":"Arch Intern Med"},{"key":"8369_CR7","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1016\/j.jaci.2010.08.025","volume":"127","author":"JC Caubet","year":"2011","unstructured":"Caubet JC, Kaiser L, Lemaitre B, Fellay B, Gervaix A, Eigenmann PA (2011) The role of penicillin in benign skin rashes in childhood: a prospective study based on drug rechallenge. J Allergy Clin Immunol 127:218\u2013222","journal-title":"J Allergy Clin Immunol"},{"key":"8369_CR8","doi-asserted-by":"publisher","first-page":"994","DOI":"10.1016\/j.jaci.2010.06.052","volume":"126","author":"A Romano","year":"2010","unstructured":"Romano A, Gaeta F, Valluzzi R, Caruso C, Rumi G, Bousquet P (2010) IgE-mediated hypersensitivity to cephalosporins: cross-reactivity and tolerability of penicillins, monobactams, and carbapenems. J Allergy Clin Immunol 126:994\u2013999","journal-title":"J Allergy Clin Immunol"},{"key":"8369_CR9","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1159\/000318844","volume":"155","author":"A Buonomo","year":"2011","unstructured":"Buonomo A, Nucera E, De Pasquale T, Pecora V, Lombardo C, Sabato V, Colagiovanni A, Rizzi A, Aruanno A, Pascolini L, Patriarca G, Schiavino D (2011) Tolerability of aztreonam in patients with cell-mediated allergy to \u03b2-lactams. Int Arch Allergy Immunol 155:155\u2013159","journal-title":"Int Arch Allergy Immunol"},{"key":"8369_CR10","doi-asserted-by":"publisher","first-page":"206","DOI":"10.5414\/CPP49206","volume":"49","author":"X Liu","year":"2011","unstructured":"Liu X, Gao N, Qiao H (2011) Cephalosporin and penicillin cross-reactivity in patients allergic to penicillins. Int J Clin Pharmacol Ther 49:206\u2013216","journal-title":"Int J Clin Pharmacol Ther"},{"key":"8369_CR11","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1016\/j.jaci.2005.10.032","volume":"117","author":"C Antunez","year":"2006","unstructured":"Antunez C, Blanca-Lopez N, Torres MJ, Mayorga C, Perez-Inestrosa E, Montanez MI, Fernandez T, Blanca M (2006) Immediate allergic reactions to cephalosporins: evaluation of cross-reactivity with a panel of penicillins and cephalosporins. J Allergy Clin Immunol 117:404\u2013410","journal-title":"J Allergy Clin Immunol"},{"key":"8369_CR12","doi-asserted-by":"publisher","first-page":"3335","DOI":"10.2174\/138161206778194060","volume":"12","author":"J Gu\u00e9ant","year":"2006","unstructured":"Gu\u00e9ant J, Gu\u00e9ant-Rodriguez R, Viola M, Valluzzi R, Romano A (2006) IgE-mediated hypersensitivity to cephalosporins. Curr Pharm Des 12:3335\u20133345","journal-title":"Curr Pharm Des"},{"key":"8369_CR13","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1097\/00130832-200208000-00002","volume":"2","author":"BA Baldo","year":"2002","unstructured":"Baldo BA, Pham NH (2002) Immunoglobulin E binding determinants on beta-lactam drugs. Curr Opin Allergy Clin Immunol 2:297\u2013300","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"8369_CR14","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1331\/JAPhA.2008.07006","volume":"48","author":"D DePestel","year":"2008","unstructured":"DePestel D, Benninger M, Danziger L, LaPlante K, May C, Luskin A, Pichichero M, Hadley J (2008) Cephalosporin use in treatment of patients with penicillin allergies. J Am Pharm Assoc 48:530\u2013540","journal-title":"J Am Pharm Assoc"},{"issue":"3 Suppl","key":"8369_CR15","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.1177\/03946320110240S307","volume":"24","author":"S Caimmi","year":"2011","unstructured":"Caimmi S, Caimmi D, Lombardi E, Crisafulli G, Franceschini F, Ricci G, Marseglia G (2011) Antibiotic allergy. Int J Immunopathol Pharmacol 24(3 Suppl):S47\u2013S53","journal-title":"Int J Immunopathol Pharmacol"},{"key":"8369_CR16","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1385\/CRIAI:24:3:201","volume":"24","author":"R Solensky","year":"2003","unstructured":"Solensky R (2003) Hypersensitivity reactions to beta-lactam antibiotics. Clin Rev Allergy Immunol 24:201\u2013219","journal-title":"Clin Rev Allergy Immunol"},{"key":"8369_CR17","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1016\/j.amjmed.2007.12.005","volume":"121","author":"AB Yates","year":"2008","unstructured":"Yates AB (2008) Management of patients with a history of allergy to beta-lactam antibiotics. Am J Med 121:572\u2013576","journal-title":"Am J Med"},{"key":"8369_CR18","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1517\/14740338.2012.643866","volume":"11","author":"P Lagace-Wiens","year":"2012","unstructured":"Lagace-Wiens P, Rubinstein E (2012) Adverse reactions to beta-lactam antimicrobials. Expert Opin Drug Saf 11:381\u2013399","journal-title":"Expert Opin Drug Saf"},{"key":"8369_CR19","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1111\/j.1398-9995.2006.01246.x","volume":"62","author":"C Ponvert","year":"2007","unstructured":"Ponvert C, Weilenmann C, Wassenberg J, Walecki P, Bourgeois M, de Blic J, Scheinmann P (2007) Allergy to betalactam antibiotics in children: a prospective follow-up study in retreated children after negative responses in skin and challenge tests. Allergy 62:42\u201346","journal-title":"Allergy"},{"key":"8369_CR20","doi-asserted-by":"publisher","first-page":"778e1","DOI":"10.1016\/j.amjmed.2009.01.034","volume":"122","author":"E Macy","year":"2009","unstructured":"Macy E, Poon KWT (2009) Self-reported antibiotic allergy incidence and prevalence: age and sex effects. Am J Med 122:778e1\u2013e7","journal-title":"Am J Med"},{"key":"8369_CR21","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.anai.2011.11.006","volume":"108","author":"E Macy","year":"2012","unstructured":"Macy E, Ho NJ (2012) Multiple drug intolerance syndrome: prevalence, clinical characteristics and management. Ann Allergy Asthma Immunol 108:88\u201393","journal-title":"Ann Allergy Asthma Immunol"},{"key":"8369_CR22","doi-asserted-by":"publisher","first-page":"1166","DOI":"10.1046\/j.1365-2133.2002.05021.x","volume":"147","author":"CN Renn","year":"2002","unstructured":"Renn CN, Straff W, Dorfmuller A, Al-Masaoudi T, Merk HF, Sachs B (2002) Amoxicillin-induced exanthema in young adults with infectious mononucleosis: demonstration of drug-specific lymphocyte reactivity. Br J Derm 147:1166\u20131170","journal-title":"Br J Derm"},{"key":"8369_CR23","first-page":"223","volume":"37","author":"M Viola","year":"2005","unstructured":"Viola M, Quaratino D, Gaeta F, Valluzzi RL, Caruso C, Rumi G, Romano A (2005) Allergic reactions to antibiotics, mainly beta-lactams: facts and controversies. Eur Ann Allergy Clin Immunol 37:223\u2013229","journal-title":"Eur Ann Allergy Clin Immunol"},{"key":"8369_CR24","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1111\/j.1399-3038.2011.01204.x","volume":"22","author":"M Atanaskovic-Markovic","year":"2011","unstructured":"Atanaskovic-Markovic M (2011) Educational case series: beta-lactam allergy and cross-reactivity. Ped Allergy Immunol 22:770\u2013775","journal-title":"Ped Allergy Immunol"},{"key":"8369_CR25","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1016\/j.mcna.2010.04.006","volume":"94","author":"MJ Torres","year":"2010","unstructured":"Torres MJ, Blanca M (2010) The complex clinical picture of beta-lactam hypersensitivity: penicillins, cephalosporins, monobactams, carbapenems, and clavans. Med Clin N Am 94:805\u2013820","journal-title":"Med Clin N Am"},{"key":"8369_CR26","first-page":"157","volume":"39","author":"ML Palma-Carlos","year":"2007","unstructured":"Palma-Carlos ML, Palma-Carlos AG, Medina M (2007) \u201cIn vivo\u201d and \u201cin vitro\u201d tests in the diagnosis of beta-lactams allergy. Eur Ann Allergy Clin Immunol 39:157\u2013161","journal-title":"Eur Ann Allergy Clin Immunol"},{"key":"8369_CR27","first-page":"117","volume":"41","author":"R Silva","year":"2009","unstructured":"Silva R, Cruz L, Botelho C, Castro E, Cadinha S, Castel-Branco MG, Rodrigues J (2009) Immediate hypersensitivity to penicillins with negative skin tests \u2013 the value of specific IgE. Eur Ann Allergy Clin Immunol 41:117\u2013119","journal-title":"Eur Ann Allergy Clin Immunol"},{"key":"8369_CR28","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1111\/j.1398-9995.2006.01268.x","volume":"62","author":"C Fontaine","year":"2007","unstructured":"Fontaine C, Mayorga C, Bousquet PJ, Arnoux B, Torres MJ, Blanca M, Demoly P (2007) Relevance of the determination of serum-specific IgE antibodies in the diagnosis of immediate beta-lactam allergy. Allergy 62:47\u201352","journal-title":"Allergy"},{"key":"8369_CR29","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1034\/j.1398-9995.2003.00585.x","volume":"58","author":"MJ Torres","year":"2003","unstructured":"Torres MJ, Blanca M (2003) Letter to the editor. Allergy 58:452","journal-title":"Allergy"},{"key":"8369_CR30","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1111\/j.1365-2222.2007.02867.x","volume":"38","author":"PJ Bousquet","year":"2007","unstructured":"Bousquet PJ, Pipet A, Bousquet-Rouanet L, Demoly P (2007) Oral challenge are needed in the diagnosis of beta-lactam hypersensitivity. Clin Exp Allergy 38:185\u2013190","journal-title":"Clin Exp Allergy"},{"key":"8369_CR31","doi-asserted-by":"publisher","first-page":"872","DOI":"10.1111\/j.1398-9995.2007.01463.x","volume":"62","author":"PJ Bousquet","year":"2007","unstructured":"Bousquet PJ, Kvedariene V, Co-Minh HB, Martins P, Rongier M, Arnoux B, Demoly P (2007) Clinical presentation and time course in hypersensitivity reactions to beta-lactams. Allergy 62:872\u2013876","journal-title":"Allergy"},{"key":"8369_CR32","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/j.anai.2010.08.002","volume":"105","author":"Joint Task Force on Practice Parameters; American Academy of Allergy, Asthma and Immunology; American College of Allergy, Asthma and Immunology; Joint Council of Allergy, Asthma and Immunology","year":"2010","unstructured":"Joint Task Force on Practice Parameters; American Academy of Allergy, Asthma and Immunology; American College of Allergy, Asthma and Immunology; Joint Council of Allergy, Asthma and Immunology (2010) Drug allergy: an updated practice parameter. Ann Allergy Asthma Immunol 105:259\u2013273, 273e1-e78","journal-title":"Ann Allergy Asthma Immunol"},{"key":"8369_CR33","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1056\/NEJM197107012850104","volume":"285","author":"NF Adkinson Jr","year":"1971","unstructured":"Adkinson NF Jr, Thompson WL, Maddrey WC, Lichtenstein LM (1971) Routine use of penicillin skin testing on an inpatient service. N Engl J Med 285:22\u201324","journal-title":"N Engl J Med"},{"key":"8369_CR34","doi-asserted-by":"crossref","first-page":"12","DOI":"10.7812\/TPP\/08-073","volume":"13","author":"E Macy","year":"2009","unstructured":"Macy E, Schatz M, Lin C, Poon KWT (2009) The falling rate of positive penicillin skin tests from 1995 to 2007. Permanente J 13:12\u201318","journal-title":"Permanente J"},{"key":"8369_CR35","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1016\/S1081-1206(10)60973-8","volume":"97","author":"BC Jost","year":"2006","unstructured":"Jost BC, Wedner HJ, Bloomberg GR (2006) Elective penicillin skin testing in a pediatric outpatient setting. Ann Allergy Asthma Immunol 97:807\u2013812","journal-title":"Ann Allergy Asthma Immunol"},{"key":"8369_CR36","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1016\/S1081-1206(10)61100-3","volume":"97","author":"M Park","year":"2006","unstructured":"Park M, Markus P, Matesic D, Li JTC (2006) Safety and effectiveness of a preoperative allergy clinic in decreasing vancomycin use in patients with a history of penicillin allergy. Ann Allergy Asthma Immunol 97:681\u2013687","journal-title":"Ann Allergy Asthma Immunol"},{"key":"8369_CR37","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1159\/000288284","volume":"152","author":"E Lin","year":"2010","unstructured":"Lin E, Saxon A, Riedl M (2010) Penicillin allergy: value of including amoxicillin as a determinant in penicillin skin testing. Int Arch Allergy Immunol 152:313\u2013318","journal-title":"Int Arch Allergy Immunol"},{"key":"8369_CR38","doi-asserted-by":"crossref","unstructured":"Macy E, Ngor EW (2013) Safely diagnosing clinically significant penicillin allergy using only penicilloyl-poly-lysine, penicillin, and oral amoxicillin. J Allergy Clin Immunol In Practice (in press)","DOI":"10.1016\/j.jaci.2012.12.1499"},{"key":"8369_CR39","doi-asserted-by":"publisher","first-page":"1151","DOI":"10.1034\/j.1398-9995.2002.23700.x","volume":"57","author":"E Macy","year":"2002","unstructured":"Macy E, Burchette RJ (2002) Oral antibiotic adverse reactions after penicillin testing: multi-year follow-up. Allergy 57:1151\u20131158","journal-title":"Allergy"},{"key":"8369_CR40","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1016\/j.otohns.2006.10.007","volume":"136","author":"ME Pichichero","year":"2007","unstructured":"Pichichero ME, Casey JR (2007) Safe use of selected cephalosporins in penicillin-allergic patients: meta-analysis. Otolaryngol Head Neck Surg 136:340\u2013347","journal-title":"Otolaryngol Head Neck Surg"},{"key":"8369_CR41","doi-asserted-by":"crossref","first-page":"31","DOI":"10.7812\/TPP\/11-025","volume":"15","author":"E Macy","year":"2011","unstructured":"Macy E, Ho NJ (2011) Adverse reactions associated with therapeutic antibiotic use after penicillin skin testing. Perm J 15:31\u201337","journal-title":"Perm J"},{"key":"8369_CR42","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.anai.2010.06.014","volume":"105","author":"E Macy","year":"2010","unstructured":"Macy E, Goldberg B, Poon KWT (2010) Use of commercial anti-penicillin-IgE FEIAs to diagnose penicillin allergy. Ann Allergy Asthma Immunol 105:136\u2013141","journal-title":"Ann Allergy Asthma Immunol"},{"key":"8369_CR43","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/j.annemergmed.2008.12.034","volume":"54","author":"A Raja","year":"2008","unstructured":"Raja A, Lindsell CJ, Bernstein JA, Codispoti CD, Moellman JJ (2008) The use of penicillin skin testing to assess the prevalence of penicillin allergy in an emergency department setting. Ann Emerg Med 54:72\u201377","journal-title":"Ann Emerg Med"},{"key":"8369_CR44","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1111\/j.1398-9995.2008.01874.x","volume":"64","author":"A Romano","year":"2009","unstructured":"Romano A, Bousquet-Rouanet L, Viola M, Gaeta F, Demoly P, Bousquet PJ (2009) Benzylpenicillin skin testing is still important in diagnosing immediate hypersensitivity reactions to penicillin. Allergy 64:249\u2013253","journal-title":"Allergy"},{"key":"8369_CR45","doi-asserted-by":"publisher","first-page":"1595","DOI":"10.1111\/j.1365-2222.2011.03834.x","volume":"41","author":"MJ Torres","year":"2011","unstructured":"Torres MJ, Romano A, Blanca-Lopez N, Dona I, Canto G, Ariza A, Aranda A, Montanez MI, Mayorga C, Blanca M (2011) Immunoglobulin E-mediated hypersensitivity to amoxicillin: in vivo and in vitro comparative studies between an injectable therapeutic compound and a new commercial compound. Clin Exp Allergy 41:1595\u20131601","journal-title":"Clin Exp Allergy"},{"key":"8369_CR46","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1159\/000314367","volume":"153","author":"MA Mark","year":"2010","unstructured":"Mark MA, Koch CA, Klemawesch P, Joshi A, Li JT (2010) Increased adverse drug reactions to cephalosporins in penicillin allergy patients with positive penicillin skin test. Int Arch Allergy Immunol 153:268\u2013273","journal-title":"Int Arch Allergy Immunol"},{"key":"8369_CR47","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/S1081-1206(10)60621-7","volume":"99","author":"MA Park","year":"2007","unstructured":"Park MA, Matesic D, Markus PJ, Li JTC (2007) Female sex as a risk factor for penicillin allergy. Ann Allergy Asthma Immunol 99:54\u201358","journal-title":"Ann Allergy Asthma Immunol"},{"key":"8369_CR48","doi-asserted-by":"publisher","first-page":"1498","DOI":"10.1111\/j.1365-2222.2011.03837.x","volume":"41","author":"E Macy","year":"2011","unstructured":"Macy E (2011) The clinical evaluation of penicillin allergy: what is necessary, sufficient, and safe given the materials currently available? Clin Exp Allergy 41:1498\u20131501","journal-title":"Clin Exp Allergy"},{"key":"8369_CR49","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1016\/S0091-6749(97)70159-3","volume":"100","author":"E Macy","year":"1997","unstructured":"Macy E, Richter PK, Falkoff R, Zeiger RS (1997) Skin testing with penicilloate and penilloate prepared by an improved method: amoxicillin oral challenge in patients with negative skin test responses to penicillin reagents. J Allergy Clin Immunol 100:586\u2013591","journal-title":"J Allergy Clin Immunol"},{"key":"8369_CR50","doi-asserted-by":"publisher","first-page":"1638","DOI":"10.1016\/j.jaci.2010.12.1125","volume":"127","author":"E Macy","year":"2011","unstructured":"Macy E (2011) Penicillin allergy might not be very common in subjects with cephaloszorin allergy. J Allergy Clin Immunol 127:1638","journal-title":"J Allergy Clin Immunol"},{"key":"8369_CR51","doi-asserted-by":"publisher","first-page":"1638","DOI":"10.1016\/j.jaci.2010.12.1126","volume":"127","author":"A Romano","year":"2011","unstructured":"Romano A, Gaeta F, Valluzzi RL, Caruso C, Rumi G, Bousquet PJ (2011) Reply. J Allergy Clin Immunol 127:1638\u20131639","journal-title":"J Allergy Clin Immunol"},{"key":"8369_CR52","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1067\/mai.2003.1385","volume":"111","author":"E Macy","year":"2003","unstructured":"Macy E, Mangat R, Burchette RJ (2003) Penicillin skin testing in advance of need: multiyear follow-up in 568 test result-negative subjects exposed to oral penicillins. J Allergy Clin Immunol 111:1111\u20131115","journal-title":"J Allergy Clin Immunol"},{"key":"8369_CR53","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1177\/039463200802100215","volume":"21","author":"G Patriarca","year":"2008","unstructured":"Patriarca G, Schiavino D, Lombardo C, Altomonte G, De Cinti M, Buonomo A, Nucera E (2008) Tolerability of aztreonam in patients with IgE-mediated hypersensitivity to beta-lactams. Int J Immunopathol Pharmacol 21:375\u2013379","journal-title":"Int J Immunopathol Pharmacol"},{"key":"8369_CR54","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1159\/000318844","volume":"155","author":"A Buonomo","year":"2011","unstructured":"Buonomo A, Nucera E, De Pasquale T, Pecora V, Lombardo C, Sabato V, Colgiovanni A, Rizzi A, Aruanno A, Pascolini L, Patriarca G, Schiavino D (2011) Tolerabilty of aztreonam in patients with cell-mediated allergy to beta-lactams. Int Arch Allergy Immunol 155:155\u2013159","journal-title":"Int Arch Allergy Immunol"}],"container-title":["Clinical Reviews in Allergy & Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12016-013-8369-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12016-013-8369-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12016-013-8369-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12016-013-8369-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,8]],"date-time":"2024-05-08T03:31:02Z","timestamp":1715139062000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12016-013-8369-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,4]]},"references-count":54,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["8369"],"URL":"https:\/\/doi.org\/10.1007\/s12016-013-8369-8","relation":{},"ISSN":["1080-0549","1559-0267"],"issn-type":[{"value":"1080-0549","type":"print"},{"value":"1559-0267","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,4]]},"assertion":[{"value":"4 April 2013","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}