{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:06:35Z","timestamp":1791219995615,"version":"4.1.0"},"reference-count":91,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2011,2,3]],"date-time":"2011-02-03T00:00:00Z","timestamp":1296691200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuromol Med"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1007\/s12017-011-8143-0","type":"journal-article","created":{"date-parts":[[2011,2,2]],"date-time":"2011-02-02T10:27:13Z","timestamp":1296642433000},"page":"138-150","source":"Crossref","is-referenced-by-count":34,"title":["Analysis of Structural and Molecular Events Associated with Adult Rat Optic Chiasm and Nerves Demyelination and Remyelination; Possible Role for 3rd Ventricle Proliferating Cells"],"prefix":"10.1007","volume":"13","author":[{"given":"Sabah","family":"Mozafari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Javan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Amin","family":"Sherafat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javad","family":"Mirnajafi-Zadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motahareh","family":"Heibatollahi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahram","family":"Pour-Beiranvand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taki","family":"Tiraihi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abolhasan","family":"Ahmadiani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2011,2,3]]},"reference":[{"key":"8143_CR1","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/0006-8993(88)90557-4","volume":"462","author":"JC Arezzo","year":"1988","unstructured":"Arezzo, J. C., Brosnan, C. F., Schroeder, C. E., Litwak, M. S., & Bornstein, M. B. (1988). Electrophysiological analysis of factors involved in the primary demyelinating diseases: The rabbit eye model system. Brain Research, 462, 286\u2013300.","journal-title":"Brain Research"},{"key":"8143_CR2","unstructured":"Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., & Struhl, K. (2002). Short protocols in molecular biology, (Ch. 2.4). New York: Wiley."},{"key":"8143_CR3","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1152\/physrev.2001.81.2.871","volume":"81","author":"N Baumann","year":"2001","unstructured":"Baumann, N., & Pham-Dinh, D. (2001). Biology of oligodendrocyte and myelin in the mammalian central nervous system. Physiological Reviews, 81, 871\u2013927.","journal-title":"Physiological Reviews"},{"key":"8143_CR4","first-page":"159","volume":"208","author":"R Beck","year":"1983","unstructured":"Beck, R., Schatz, N., & Savino, J. (1983). Involvement of the optic chiasm, optic tract and geniculo calcarine visual system in multiple sclerosis. Bulletin of the Belgian Societies of Ophthalmology, 208, 159\u2013191.","journal-title":"Bulletin of the Belgian Societies of Ophthalmology"},{"key":"8143_CR5","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s00427-007-0158-z","volume":"217","author":"OJ Bronchain","year":"2007","unstructured":"Bronchain, O. J., Pollet, N., Ymlahi-Ouazzani, Q., Dhorne-Pollet, S., Helbling, J. C., Lecarpentier, J. E., et al. (2007). The olig family: Phylogenetic analysis and early gene expression in Xenopus tropicalis. Development Genes and Evolution, 217, 485\u2013497.","journal-title":"Development Genes and Evolution"},{"key":"8143_CR6","doi-asserted-by":"crossref","first-page":"18183","DOI":"10.1073\/pnas.0506535102","volume":"102","author":"A Buffo","year":"2005","unstructured":"Buffo, A., Vosko, M. R., Ert\u00fcrk, D., Hamann, G. F., Jucker, M., Rowitch, D., et al. (2005). Expression pattern of the transcription factor Olig2 in response to brain injuries: Implications for neuronal repair. Proceedings of the National Academy of Sciences of the United States of America, 102, 18183\u201318188.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"8143_CR7","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/dneu.20588","volume":"68","author":"C Cantarella","year":"2008","unstructured":"Cantarella, C., Cayre, M., Magalon, K., & Durbec, P. (2008). Intranasal HB-EGF administration favors adult SVZ cell mobilization to demyelinated lesions in mouse corpus callosum. Developmental Neurobiology, 68, 223\u2013236.","journal-title":"Developmental Neurobiology"},{"key":"8143_CR8","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1093\/brain\/121.2.293","volume":"121","author":"WM Carroll","year":"1998","unstructured":"Carroll, W. M., Jennings, A. R., & Ironside, L. J. (1998). Identification of the adult resting progenitor cell by autoradiographic tracking of oligodendrocyte precursors in experimental CNS demyelination. Brain, 121, 293\u2013302.","journal-title":"Brain"},{"key":"8143_CR9","first-page":"17","volume":"19","author":"WM Carroll","year":"1983","unstructured":"Carroll, W. M., Jennings, A., & Mastaglia, F. L. (1983). Experimental demyelinating optic neuropathy: A model for combined morphological and electrophysiological studies. Clinical and Experimental Neurology, 19, 17\u201328.","journal-title":"Clinical and Experimental Neurology"},{"key":"8143_CR10","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1016\/j.mcn.2006.01.004","volume":"31","author":"M Cayre","year":"2006","unstructured":"Cayre, M., Bancila, M., Virard, I., Borges, A., & Durbec, P. (2006). Migrating and myelinating potential of subventricular zone neural progenitor cells in white matter tracts of the adult rodent brain. Molecular and Cellular Neurosciences, 31, 748\u2013758.","journal-title":"Molecular and Cellular Neurosciences"},{"key":"8143_CR11","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1056\/NEJMoa010994","volume":"346","author":"A Chang","year":"2002","unstructured":"Chang, A., Tourtellotte, W. W., Rudick, R., & Trapp, B. D. (2002). Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis. New England Journal of Medicine, 346, 165\u2013173.","journal-title":"New England Journal of Medicine"},{"key":"8143_CR12","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1038\/35000219","volume":"403","author":"MS Chen","year":"2000","unstructured":"Chen, M. S., Huber, A. B., van der Haar, M., Frank, M., Schnell, L., Spillmann, A. A., et al. (2000). Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1. Nature, 403, 434\u2013439.","journal-title":"Nature"},{"key":"8143_CR13","first-page":"11","volume":"5","author":"T Chitnis","year":"2005","unstructured":"Chitnis, T., Imitola, J., & Khoury, S. J. (2005). Therapeutic strategies to prevent neurodegeneration and promote regeneration in multiple sclerosis. Current Drug Targets, 5, 11\u201326.","journal-title":"Current Drug Targets"},{"key":"8143_CR14","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1097\/00001756-200303240-00022","volume":"14","author":"L Chouaf-Lakhdar","year":"2003","unstructured":"Chouaf-Lakhdar, L., Fevre-Montange, M., Brisson, C., Strazielle, N., Gamrani, H., & Didier-Bazes, M. (2003). Proliferative activity and nestin expression in periventricular cells of the adult rat brain. Neuroreport, 14, 633\u2013636.","journal-title":"Neuroreport"},{"key":"8143_CR15","doi-asserted-by":"crossref","first-page":"7665","DOI":"10.1523\/JNEUROSCI.15-11-07665.1995","volume":"15","author":"RJ Colello","year":"1995","unstructured":"Colello, R. J., Devey, L. R., Imperato, E., & Pott, U. (1995). The chronology of oligodendrocyte differentiation in the rat optic nerve: Evidence for a signaling step initiating myelination in the CNS. Journal of Neuroscience, 15, 7665\u20137672.","journal-title":"Journal of Neuroscience"},{"key":"8143_CR16","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1002\/jnr.10411","volume":"69","author":"L Decker","year":"2002","unstructured":"Decker, L., Picard-Riera, N., Lachapelle, F., & Baron-Van Evercooren, A. (2002). Growth factor treatment promotes mobilization of young but not aged adult subventricular zone precursors in response to demyelination. Journal of Neuroscience Research, 69, 763\u2013771.","journal-title":"Journal of Neuroscience Research"},{"key":"8143_CR17","doi-asserted-by":"crossref","first-page":"5046","DOI":"10.1523\/JNEUROSCI.17-13-05046.1997","volume":"17","author":"F Doetsch","year":"1997","unstructured":"Doetsch, F., Garcia-Verdugo, J. M., & Alvarez-Buylla, A. (1997). Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain. Journal of Neuroscience, 17, 5046\u20135061.","journal-title":"Journal of Neuroscience"},{"key":"8143_CR18","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.brainres.2003.08.070","volume":"1008","author":"AG Douena","year":"2004","unstructured":"Douena, A. G., Dongb, L., Vanancec, S., Mungerd, R., Hogand, M. J., Thompsond, C. S., et al. (2004). Regulation of nestin expression after cortical ablation in adult rat brain. Brain Research, 1008, 139\u2013146.","journal-title":"Brain Research"},{"key":"8143_CR19","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.neuron.2005.09.004","volume":"48","author":"M Dubois-Dalcq","year":"2005","unstructured":"Dubois-Dalcq, M., Ffrench-Constant, C., & Franklin, R. J. M. (2005). Enhancing central nervous system remyelination in multiple sclerosis. Neuron, 48, 9\u201312.","journal-title":"Neuron"},{"key":"8143_CR20","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1046\/j.1469-7580.1997.19010035.x","volume":"190","author":"ID Duncan","year":"1997","unstructured":"Duncan, I. D., & Hoffman, R. L. (1997). Schwann cell invasion of the central nervous system of the myelin mutants. Journal of Anatomy, 190, 35\u201349.","journal-title":"Journal of Anatomy"},{"key":"8143_CR21","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1002\/jnr.20063","volume":"76","author":"JM Edgar","year":"2004","unstructured":"Edgar, J. M., & Garbern, J. (2004). The myelinated axon is dependent on the myelinating cell for support and maintenance: Molecules involved. Journal of Neuroscience Research, 76, 593\u2013598.","journal-title":"Journal of Neuroscience Research"},{"key":"8143_CR22","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.pneurobio.2005.04.002","volume":"75","author":"JG Emsley","year":"2005","unstructured":"Emsley, J. G., Mitchell, B. D., Kempermann, G., & Macklis, J. D. (2005). Adult neurogenesis and repair of the adult CNS with neural progenitors, precursors, and stem cells. Progress in Neurobiology, 75, 321\u2013341.","journal-title":"Progress in Neurobiology"},{"key":"8143_CR23","doi-asserted-by":"crossref","first-page":"3059","DOI":"10.1111\/j.1460-9568.2005.04499.x","volume":"22","author":"C Ernst","year":"2005","unstructured":"Ernst, C., & Christie, B. R. (2005). Nestin-expressing cells and their relationship to mitotically active cells in the subventricular zones of the adult rat. The European Journal of Neuroscience, 22, 3059\u20133066.","journal-title":"The European Journal of Neuroscience"},{"key":"8143_CR24","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.mcn.2004.06.015","volume":"27","author":"SPJ Fancy","year":"2004","unstructured":"Fancy, S. P. J., Zhao, C., & Franklin, R. J. M. (2004). Increased expression of Nkx2.2 and Olig2 identifies reactive oligodendrocyte progenitor cells responding to demyelination in the adult CNS. Molecular and Cellular Neurosciences, 27, 247\u2013254.","journal-title":"Molecular and Cellular Neurosciences"},{"key":"8143_CR25","first-page":"11","volume-title":"The clinical neuropsychiatry of multiple sclerosis","author":"A Feinstein","year":"1999","unstructured":"Feinstein, A. (1999). The clinical neuropsychiatry of multiple sclerosis (pp. 11\u201312). Cambridge: Cambridge University Press."},{"key":"8143_CR26","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/0306-4522(96)00282-5","volume":"75","author":"PA Felts","year":"1996","unstructured":"Felts, P. A., & Smith, K. J. (1996). Blood-brain barrier permeability in astrocyte-free regions of the central nervous system remyelinated by Schwann cells. Neuroscience, 75, 643\u2013655.","journal-title":"Neuroscience"},{"key":"8143_CR27","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1177\/135245859700300205","volume":"2","author":"RJM Franklin","year":"1997","unstructured":"Franklin, R. J. M., & Blakemore, W. F. (1997). To what extent is oligodendrocyte progenitor migration a limiting factor in the remyelination of Multiple Sclerosis lesions? Multiple Sclerosis, 2, 84\u201387.","journal-title":"Multiple Sclerosis"},{"key":"8143_CR28","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1002\/(SICI)1097-4547(19971015)50:2<337::AID-JNR21>3.0.CO;2-3","volume":"50","author":"RJM Franklin","year":"1997","unstructured":"Franklin, R. J. M., Gilson, J. M., & Blakemore, W. F. (1997). Local recruitment of remyelinating cells in the repair of demyelination in the central nervous system. Journal of Neuroscience Research, 50, 337\u2013344.","journal-title":"Journal of Neuroscience Research"},{"key":"8143_CR29","doi-asserted-by":"crossref","first-page":"7619","DOI":"10.1523\/JNEUROSCI.0855-06.2006","volume":"26","author":"L Gao","year":"2006","unstructured":"Gao, L., & Miller, R. H. (2006). Specification of optic nerve oligodendrocyte precursors by retinal ganglion cell axons. Journal of Neuroscience, 26, 7619\u20137628.","journal-title":"Journal of Neuroscience"},{"key":"8143_CR30","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0896-6273(00)80359-1","volume":"19","author":"JM Gensert","year":"1997","unstructured":"Gensert, J. M., & Goldman, J. E. (1997). Endogenous progenitors remyelinate demyelinated axons in the adult CNS. Neuron, 19, 197\u2013203.","journal-title":"Neuron"},{"key":"8143_CR31","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1001\/archneur.1973.00490280074011","volume":"29","author":"NR Ghatak","year":"1973","unstructured":"Ghatak, N. R., Hirano, A., Doron, Y., & Zimmerman, H. M. (1973). Remyelination in multiple sclerosis with peripheral type myelin. Archives of Neurology, 29, 262\u2013267.","journal-title":"Archives of Neurology"},{"key":"8143_CR32","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1002\/glia.440110409","volume":"11","author":"RS Ghirnikar","year":"1994","unstructured":"Ghirnikar, R. S., & Eng, L. F. (1994). Astrocyte-Schwann interactions in cell culture. GLIA, 11, 367\u2013377.","journal-title":"GLIA"},{"key":"8143_CR33","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/s10571-009-9451-x","volume":"30","author":"M Goudarzvand","year":"2009","unstructured":"Goudarzvand, M., Javan, M., Mirnajafi-zadeh, J., Mozafari, S., & Tiraihi, T. (2009). Vitamins E and D3 attenuate demyelination and potentiate remyelination processes of hippocampal formation of rats following local injection of ethidium bromide. Cellular and Molecular Neurobiology, 30, 289\u2013299.","journal-title":"Cellular and Molecular Neurobiology"},{"key":"8143_CR34","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1038\/35000226","volume":"403","author":"T GrandPre","year":"2000","unstructured":"GrandPre, T., Nakamura, F., Vartanian, T., & Strittmatter, S. M. (2000). Identification of the Nogo inhibitor of axon regeneration as a reticulon protein. Nature, 403, 439\u2013444.","journal-title":"Nature"},{"key":"8143_CR35","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1126\/science.280.5369.1610","volume":"280","author":"I Griffiths","year":"1998","unstructured":"Griffiths, I., Klugmann, M., Anderson, T., Yool, D., Thomson, C., Schwab, M. H., et al. (1998). Axonal swellings and degeneration in mice lacking the major proteolipid of myelin. Science, 280, 1610\u20131613.","journal-title":"Science"},{"key":"8143_CR36","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1007\/BF01190837","volume":"18","author":"IR Griffiths","year":"1989","unstructured":"Griffiths, I. R., Mitchell, L. S., McPhilemy, K., Morrison, S., Kyriakides, E., & Barrie, J. A. (1989). Expression of myelin protein genes in Schwann cells. Journal of Neurocytology, 18, 345\u2013352.","journal-title":"Journal of Neurocytology"},{"key":"8143_CR37","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.jocn.2004.08.002","volume":"12","author":"EP Guazzo","year":"2005","unstructured":"Guazzo, E. P. (2005). A technique for producing demyelination of the rat optic nerves. Journal of Clinical Neuroscience, 12, 54\u201358.","journal-title":"Journal of Clinical Neuroscience"},{"key":"8143_CR38","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/BF00687001","volume":"65","author":"Y Itoyama","year":"1985","unstructured":"Itoyama, Y., Ohnishi, A., Tateishi, J., Kuroiwa, Y., & Webster, H. D. (1985). Spinal cord multiple sclerosis lesions in Japanese patients: Schwann cell remyelination occurs in areas that lack glial fibrillary acidic protein (GFAP). Acta Neuropathologica, 65, 217\u2013223.","journal-title":"Acta Neuropathologica"},{"key":"8143_CR39","doi-asserted-by":"crossref","first-page":"9215","DOI":"10.1523\/JNEUROSCI.20-24-09215.2000","volume":"20","author":"L Jasmin","year":"2000","unstructured":"Jasmin, L., Janni, G., Moallem, T. M., Lappi, D. A., & Ohara, P. T. (2000). Schwann cells are removed from the spinal cord after effecting recovery from paraplegia. Journal of Neuroscience, 20, 9215\u20139223.","journal-title":"Journal of Neuroscience"},{"key":"8143_CR40","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1093\/brain\/120.1.27","volume":"120","author":"ND Jeffery","year":"1997","unstructured":"Jeffery, N. D., & Blakemore, W. F. (1997). Locomotor deficits induced by experimental spinal cord demyelination are abolished by spontaneous remyelination. Brain, 120, 27\u201337.","journal-title":"Brain"},{"key":"8143_CR41","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1023\/A:1022567414294","volume":"31","author":"AR Jennings","year":"2002","unstructured":"Jennings, A. R., Kirilak, Y., & Carroll, W. M. (2002). In situ characterization of oligodendrocyte progenitor cells in adult mammalian optic nerve. Journal of Neurocytology, 31, 27\u201339.","journal-title":"Journal of Neurocytology"},{"key":"8143_CR43","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1002\/(SICI)1098-1136(199802)22:2<161::AID-GLIA7>3.0.CO;2-A","volume":"22","author":"HS Keirstead","year":"1998","unstructured":"Keirstead, H. S., Levine, J. M., & Blakemore, W. F. (1998). Response of the oligodendrocyte progenitor cell population (defined by NG2 labelling) to demyelination of the adult spinal cord. GLIA, 22, 161\u2013170.","journal-title":"GLIA"},{"key":"8143_CR44","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.neulet.2008.11.058","volume":"451","author":"PN Koutsoudaki","year":"2009","unstructured":"Koutsoudaki, P. N., Skripuletza, T., Gudia, V., Moharregh-Khiabania, D., Hildebrandt, H., Trebsta, C., et al. (2009). Demyelination of the hippocampus is prominent in the cuprizone model. Neuroscience Letters, 451, 83\u201388.","journal-title":"Neuroscience Letters"},{"key":"8143_CR45","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1002\/cne.10945","volume":"467","author":"G Kronenberg","year":"2003","unstructured":"Kronenberg, G., Reuter, K., Steiner, B., Brandt, M. D., Jessberger, S., Yamaguchi, M., et al. (2003). Subpopulations of proliferating cells of the adult hippocampus respond differently to physiologic neurogenic stimuli. The Journal of Comparative Neurology, 467, 455\u2013463.","journal-title":"The Journal of Comparative Neurology"},{"key":"8143_CR46","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1097\/01.jnen.0000248559.83573.71","volume":"66","author":"T Kuhlmann","year":"2007","unstructured":"Kuhlmann, T., Remington, L., Maruschak, B., Owens, T., & Br\u00fcck, W. (2007). Nogo-A is a reliable oligodendroglial marker in adult human and mouse CNS and in demyelinated lesions. Journal of Neuropathology and Experimental Neurology, 66, 238\u2013246.","journal-title":"Journal of Neuropathology and Experimental Neurology"},{"key":"8143_CR48","doi-asserted-by":"crossref","first-page":"12623","DOI":"10.1523\/JNEUROSCI.3812-07.2007","volume":"27","author":"DC Lagace","year":"2007","unstructured":"Lagace, D. C., Whitman, M. C., Noonan, M. A., Ables, J. L., DeCarolis, N. A., Arguello, A. A., et al. (2007). Dynamic contribution of nestin-expressing stem cells to adult neurogenesis. Journal of Neuroscience, 27, 12623\u201312629.","journal-title":"Journal of Neuroscience"},{"key":"8143_CR49","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1038\/ng1095","volume":"33","author":"C Lappe-Siefke","year":"2003","unstructured":"Lappe-Siefke, C., Goebbels, S., Gravel, M., Nicksch, E., Lee, J., Braun, P. E., et al. (2003). Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination. Nature Genetics, 33, 366\u2013374.","journal-title":"Nature Genetics"},{"key":"8143_CR50","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/0092-8674(90)90662-X","volume":"60","author":"U Lendahl","year":"1990","unstructured":"Lendahl, U., Zimmerman, L. B., & McKay, R. D. (1990). CNS stem cells express a new class of intermediate filament protein. Cell, 60, 585\u2013595.","journal-title":"Cell"},{"key":"8143_CR51","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0166-2236(00)01691-X","volume":"24","author":"JM Levine","year":"2001","unstructured":"Levine, J. M., Reynolds, R., & Fawcett, J. W. (2001). The oligodendrocyte precursor cell in health and disease. Trends in Neurosciences, 24, 39\u201347.","journal-title":"Trends in Neurosciences"},{"key":"8143_CR52","first-page":"251","volume":"152","author":"W Liedtke","year":"1998","unstructured":"Liedtke, W., Edelmann, W., Chiu, F. C., Kucherlapati, R., & Raine, C. S. (1998). Experimental autoimmune encephalomyelitis in mice lacking glial fibrillary acidic protein is characterized by a more severe clinical course and an infiltrative central nervous system lesion. The American Journal of Pathology, 152, 251\u2013259.","journal-title":"The American Journal of Pathology"},{"key":"8143_CR53","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/glia.20273","volume":"54","author":"KL Ligon","year":"2006","unstructured":"Ligon, K. L., Fancy, S. P. J., Franklin, R. J. M., & Rowitch, D. H. (2006a). Olig gene function in CNS development and disease. GLIA, 54, 1\u201310.","journal-title":"GLIA"},{"key":"8143_CR54","doi-asserted-by":"crossref","first-page":"7853","DOI":"10.1073\/pnas.0511001103","volume":"103","author":"KL Ligon","year":"2006","unstructured":"Ligon, K. L., Kesari, S., Kitada, M., Sun, T., Arnett, H. A., Alberta, J. A., et al. (2006b). Development of NG2 neural progenitor cells requires Olig gene function. Proceedings of the National Academy of Sciences of the United States of America, 103, 7853\u20137858.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"8143_CR55","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.ydbio.2006.10.007","volume":"302","author":"Z Liu","year":"2007","unstructured":"Liu, Z., Hu, X., Cai, J., Liu, B., Peng, X., Wegner, M., et al. (2007). Induction of oligodendrocyte differentiation by Olig2 and Sox10: Evidence for reciprocal interactions and dosage-dependent mechanisms. Developmental Biology, 302, 683\u2013693.","journal-title":"Developmental Biology"},{"key":"8143_CR56","doi-asserted-by":"crossref","first-page":"7907","DOI":"10.1523\/JNEUROSCI.1299-06.2006","volume":"26","author":"B Menn","year":"2006","unstructured":"Menn, B., Garcia-Verdugo, J. M., Yaschine, C., Gonzalez-Perez, O., Rowitch, D., & Alvarez-Buylla, A. (2006). Origin of oligodendrocytes in the subventricular zone of the adult brain. Journal of Neuroscience, 26, 7907\u20137918.","journal-title":"Journal of Neuroscience"},{"key":"8143_CR57","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.brainres.2010.07.026","volume":"1351","author":"S Mozafari","year":"2010","unstructured":"Mozafari, S., Sherafat, M. A., Javan, M., Mirnajafi-zadeh, J., & Tiraihi, T. (2010). Visual evoked potentials and MBP Gene expression imply endogenous myelin repair in adult rat optic nerve and chiasm following local lysolecithin induced demyelination. Brain Research, 1351, 50\u201356.","journal-title":"Brain Research"},{"key":"8143_CR59","doi-asserted-by":"crossref","first-page":"4357","DOI":"10.1046\/j.1460-9568.1999.00873.x","volume":"11","author":"B Nait-Oumesmar","year":"1999","unstructured":"Nait-Oumesmar, B., Decker, L., Lachapelle, F., Avellana-Adalid, V., Bachelin, C., & Baron-Van Evercooren, A. (1999). Progenitor cells of the adult mouse subventricular zone proliferate, migrate and differentiate into oligodendrocytes after demyelination. The European Journal of Neuroscience, 11, 4357\u20134366.","journal-title":"The European Journal of Neuroscience"},{"key":"8143_CR60","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jns.2007.09.032","volume":"268","author":"B Nait-Oumesmar","year":"2008","unstructured":"Nait-Oumesmar, B., Picard-Ri\u00e9ra, N., Kerninon, C., & Baron-Van Evercooren, A. (2008). The role of SVZ-derived neural precursors in demyelinating diseases: From animal models to multiple sclerosis. Journal of Neurological Sciences, 268, 26\u201331.","journal-title":"Journal of Neurological Sciences"},{"key":"8143_CR61","doi-asserted-by":"crossref","first-page":"4694","DOI":"10.1073\/pnas.0606835104","volume":"104","author":"B Nait-Oumesmar","year":"2007","unstructured":"Nait-Oumesmar, B., Picard-Riera, N., Kerninon, C., Decker, L., Seilhean, D., H\u00f6glinger, G. U., et al. (2007). Activation of the subventricular zone in multiple sclerosis: Evidence for early glial progenitors. Proceedings of the National Academy of Sciences of the United States of America, 104, 4694\u20134699.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"8143_CR62","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1146\/annurev.neuro.30.051606.094309","volume":"31","author":"K-A Nave","year":"2008","unstructured":"Nave, K.-A., & Trapp, B. D. (2008). Axon-Glial signaling and the glial support of axon function. Annual Review of Neuroscience, 31, 535\u2013561.","journal-title":"Annual Review of Neuroscience"},{"key":"8143_CR63","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1056\/NEJM200009283431307","volume":"343","author":"JH Noseworthy","year":"2000","unstructured":"Noseworthy, J. H., Lucchinetti, C., Rodriguez, M., & Weinshenker, B. G. (2000). Multiple sclerosis. New England Journal of Medicine, 343, 938\u2013952.","journal-title":"New England Journal of Medicine"},{"key":"8143_CR65","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/S0896-6273(00)80939-3","volume":"19","author":"K Ono","year":"1997","unstructured":"Ono, K., Yasui, Y., Rutishauser, U., & Miller, R. H. (1997). Focal ventricular origin and migration of oligodendrocyte precursors into the chick optic nerve. Neuron, 19, 283\u2013292.","journal-title":"Neuron"},{"key":"8143_CR66","first-page":"389","volume":"28","author":"J Otradovec","year":"1965","unstructured":"Otradovec, J. (1965). Chiasmatic and retrochiasmatic neuritis in multiple sclerosis. (Contribution to the problem of the origin of functional disorders of the optical tract in multiple sclerosis). Ceskoslovensk\u00e1 Neurologie, 28, 389\u2013395.","journal-title":"Ceskoslovensk\u00e1 Neurologie"},{"key":"8143_CR67","doi-asserted-by":"crossref","first-page":"8487","DOI":"10.1523\/JNEUROSCI.19-19-08487.1999","volume":"19","author":"TD Palmer","year":"1999","unstructured":"Palmer, T. D., Markakis, E. A., Willhoite, A. R., Safar, F., & Gage, F. H. (1999). Fibroblast growth factor-2 activates a latent neurogenic program in neural stem cells from diverse regions of the adult CNS. Journal of Neuroscience, 19, 8487\u20138497.","journal-title":"Journal of Neuroscience"},{"key":"8143_CR68","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.expneurol.2005.10.033","volume":"197","author":"D Papadopoulos","year":"2006","unstructured":"Papadopoulos, D., Pham-Dinh, D., & Reynolds, R. (2006). Axon loss is responsible for chronic neurological deficit following inflammatory demyelination in the rat. Experimental Neurology, 197, 373\u2013385.","journal-title":"Experimental Neurology"},{"key":"8143_CR69","volume-title":"The rat brain in stereotaxic coordinates","author":"G Paxinos","year":"2007","unstructured":"Paxinos, G., & Watson, C. (2007). The rat brain in stereotaxic coordinates (6th ed.). New York: Academic press.","edition":"6"},{"key":"8143_CR70","first-page":"79","volume":"49","author":"J Pazour","year":"2006","unstructured":"Pazour, J., & Mokr\u00fd, J. (2006). Stem cell therapy for demyelinatin disorders. Acta Medica, 49, 79\u201385.","journal-title":"Acta Medica"},{"key":"8143_CR71","doi-asserted-by":"crossref","first-page":"13211","DOI":"10.1073\/pnas.192314199","volume":"99","author":"N Picard-Riera","year":"2002","unstructured":"Picard-Riera, N., Decker, L., Delarasse, C., Goude, K., Nait-Oumesmar, B., Liblau, R., et al. (2002). Experimental autoimmune encephalomyelitis mobilizes neural progenitors from the subventricular zone to undergo oligodendrogenesis in adult mice. Proceedings of the National Academy of Sciences of the United States of America, 99, 13211\u201313216.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"8143_CR72","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/jnr.20040","volume":"76","author":"N Picard-Riera","year":"2004","unstructured":"Picard-Riera, N., Nait-Oumesmar, B., & Baron-Van Evercooren, A. (2004). Endogenous adult neural stem cells: Limits and potential to repair the injured central nervous system. Journal of Neuroscience Research, 76, 223\u2013231.","journal-title":"Journal of Neuroscience Research"},{"key":"8143_CR73","doi-asserted-by":"crossref","first-page":"2713","DOI":"10.1093\/brain\/awh626","volume":"128","author":"IM Pomeroy","year":"2005","unstructured":"Pomeroy, I. M., Matthews, P. M., Frank, J. A., Jordan, E. K., & Esiri, M. M. (2005). Demyelinated neocortical lesions in marmoset autoimmune encephalomyelitis mimic those in multiple sclerosis. Brain, 128, 2713\u20132721.","journal-title":"Brain"},{"key":"8143_CR74","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1038\/ng0303-327","volume":"33","author":"B Popko","year":"2003","unstructured":"Popko, B. (2003). Myelin: Not just a conduit for conduction. Nature Genetics, 33, 327\u2013328.","journal-title":"Nature Genetics"},{"key":"8143_CR76","doi-asserted-by":"crossref","first-page":"4565","DOI":"10.1523\/JNEUROSCI.12-11-04565.1992","volume":"12","author":"BA Reynolds","year":"1992","unstructured":"Reynolds, B. A., Tetzlaff, W., & Weiss, S. (1992). A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes. Journal of Neuroscience, 12, 4565\u20134574.","journal-title":"Journal of Neuroscience"},{"key":"8143_CR78","doi-asserted-by":"crossref","first-page":"2221","DOI":"10.1093\/brain\/121.12.2221","volume":"121","author":"N Scolding","year":"1998","unstructured":"Scolding, N., Franklin, R. J. M., Stevens, S., Helding, C.-H., Compston, A., & Newcomb, J. (1998). Oligodendrocyte progenitors are present in the normal adult human CNS and in the lesions of multiple sclerosis. Brain, 121, 2221\u20132228.","journal-title":"Brain"},{"key":"8143_CR79","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1523\/JNEUROSCI.22-05-01784.2002","volume":"22","author":"RM Seaberg","year":"2002","unstructured":"Seaberg, R. M., & van der Kooy, D. (2002). Adult rodent neurogenic regions: The ventricular subependyma contains neural stem cells, but the dentate gyrus contains restricted progenitors. Journal of Neuroscience, 22, 1784\u20131793.","journal-title":"Journal of Neuroscience"},{"key":"8143_CR80","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1002\/glia.10321","volume":"45","author":"A Setzu","year":"2004","unstructured":"Setzu, A., Ffrench-Constant, C., & Franklin, R. J. M. (2004). CNS axons retain their competence for myelination throughout life. Glia, 45, 307\u2013311.","journal-title":"Glia"},{"key":"8143_CR81","doi-asserted-by":"crossref","first-page":"4627","DOI":"10.1523\/JNEUROSCI.18-12-04627.1998","volume":"18","author":"J Shi","year":"1998","unstructured":"Shi, J., Marinovich, A., & Barres, B. A. (1998). Purification and characterization of adult oligodendrocyte precursor cells from the rat optic nerve. Journal of Neuroscience, 18, 4627\u20134636.","journal-title":"Journal of Neuroscience"},{"key":"8143_CR82","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1038\/280395a0","volume":"280","author":"KJ Smith","year":"1979","unstructured":"Smith, K. J., Blakemore, W. F., & McDonald, W. I. (1979). Central remyelination restores secure conduction. Nature, 280, 395\u2013396.","journal-title":"Nature"},{"key":"8143_CR83","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0301-0082(02)00105-3","volume":"68","author":"M Stangel","year":"2002","unstructured":"Stangel, M., & Hartung, H. P. (2002). Remyelinating strategies for the treatment of multiple sclerosis. Progress in Neurobiology, 68, 361\u2013376.","journal-title":"Progress in Neurobiology"},{"key":"8143_CR84","first-page":"391","volume":"130","author":"RR Sturrock","year":"1980","unstructured":"Sturrock, R. R., & Smart, I. H. (1980). A morphological study of the mouse subependymal layer from embryonic life to old age. Journal of Anatomy, 130, 391\u2013415.","journal-title":"Journal of Anatomy"},{"key":"8143_CR85","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.expneurol.2004.05.038","volume":"192","author":"JF Talbott","year":"2005","unstructured":"Talbott, J. F., Loy, D. N., Liu, Y., Qiu, M. S., Bunge, M. B., Rao, M. S., et al. (2005). Endogenous Nkx2. 2+\/Olig2+ oligodendrocyte precursor cells fail to remyelinate the demyelinated adult rat spinal cord in the absence of astrocytes. Experimental Neurology, 192, 11\u201324.","journal-title":"Experimental Neurology"},{"key":"8143_CR86","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0166-2236(00)02096-8","volume":"25","author":"H-H Tsai","year":"2002","unstructured":"Tsai, H.-H., & Miller, R. H. (2002). Glial cell migration directed by axon guidance cues. Trends in Neurosciences, 25, 173\u2013175.","journal-title":"Trends in Neurosciences"},{"key":"8143_CR87","doi-asserted-by":"crossref","first-page":"7599","DOI":"10.1523\/JNEUROSCI.16-23-07599.1996","volume":"16","author":"S Weiss","year":"1996","unstructured":"Weiss, S., Dunne, C., Hewson, J., Wohl, C., Wheatley, M., Peterson, A. C., et al. (1996). Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis. Journal of Neuroscience, 16, 7599\u20137609.","journal-title":"Journal of Neuroscience"},{"key":"8143_CR88","doi-asserted-by":"crossref","first-page":"2510","DOI":"10.1007\/s00018-004-4144-6","volume":"61","author":"C Wiese","year":"2004","unstructured":"Wiese, C., Rolletscheka, A., Kaniaa, G., Blyszczuka, P., Tarasovb, K. V., Tarasovab, Y., et al. (2004). Nestin expression\u2014A property of multi-lineage progenitor cells? Cellular and Molecular Life Sciences, 61, 2510\u20132522.","journal-title":"Cellular and Molecular Life Sciences"},{"key":"8143_CR89","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/labinvest.3780235","volume":"81","author":"DM Wingerchuk","year":"2001","unstructured":"Wingerchuk, D. M., Lucchinetti, C. F., & Noseworthy, J. H. (2001). Biology of disease, multiple sclerosis: Current pathophysiological concepts. Laboratory Investigation, 81, 263\u2013281.","journal-title":"Laboratory Investigation"},{"key":"8143_CR90","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1523\/JNEUROSCI.18-02-00601.1998","volume":"18","author":"G Wolswijk","year":"1998","unstructured":"Wolswijk, G. (1998). Chronic stage multiple sclerosis lesions contain a relatively quiescent population of oligodendrocyte precursor cells. Journal of Neuroscience, 18, 601\u2013609.","journal-title":"Journal of Neuroscience"},{"key":"8143_CR91","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1242\/dev.109.3.691","volume":"109","author":"G Wolswijk","year":"1990","unstructured":"Wolswijk, G., Riddle, P. N., & Noble, M. (1990). Coexistence of perinatal and adult forms of a glial progenitor cell during development of the rat optic nerve. Development, 109, 691\u2013698.","journal-title":"Development"},{"key":"8143_CR92","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1002\/(SICI)1098-1136(19990201)25:3<216::AID-GLIA2>3.0.CO;2-L","volume":"25","author":"RH Woodruff","year":"1999","unstructured":"Woodruff, R. H., & Franklin, R. J. M. (1999a). Demyelination and remyelination of the caudal cerebellar peduncle of adult rats following stereotaxic injections of lysolecithin, ethidium bromide, and complement\/anti-galactocerebroside: A comparative study. Glia, 25, 216\u2013228.","journal-title":"Glia"},{"key":"8143_CR93","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1046\/j.1365-2990.1999.00172.x","volume":"25","author":"RH Woodruff","year":"1999","unstructured":"Woodruff, R. H., & Franklin, R. J. M. (1999b). The expression of myelin protein mRNAs during remyelination of lysolecithin-induced demyelination. Neuropathology and Applied Neurobiology, 25, 226\u2013235.","journal-title":"Neuropathology and Applied Neurobiology"},{"key":"8143_CR94","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.expneurol.2004.12.021","volume":"192","author":"Y Xu","year":"2005","unstructured":"Xu, Y., Tamamaki, N., Noda, T., Kimura, K., Itokazu, Y., Matsumoto, N., et al. (2005). Neurogenesis in the ependymal layer of the adult rat 3rd ventricle. Experimental Neurology, 192, 251\u2013264.","journal-title":"Experimental Neurology"},{"key":"8143_CR95","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1097\/00001756-200006260-00037","volume":"11","author":"M Yamaguchi","year":"2000","unstructured":"Yamaguchi, M., Saito, H., Suzuki, M., & Mori, K. (2000). Visualization of neurogenesis in the central nervous system using nestin promoter-GFP transgenic mice. Neuroreport, 11, 1991\u20131996.","journal-title":"Neuroreport"},{"key":"8143_CR96","doi-asserted-by":"crossref","first-page":"4089","DOI":"10.1073\/pnas.96.7.4089","volume":"96","author":"SC Zhang","year":"1999","unstructured":"Zhang, S. C., Ge, B., & Duncan, I. D. (1999). Adult brain retains the potential to generate oligodendroglial progenitors with extensive myelination capacity. Proceedings of the National Academy of Sciences of the United States of America, 96, 4089\u20134094.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"8143_CR97","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1177\/10738584070130041001","volume":"13","author":"V Zujovic","year":"2007","unstructured":"Zujovic, V. (2007). Remyelination of the central nervous system: A valuable contribution from the periphery. Neuroscientist, 13, 383\u2013391.","journal-title":"Neuroscientist"}],"container-title":["NeuroMolecular Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12017-011-8143-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12017-011-8143-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12017-011-8143-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,18]],"date-time":"2021-11-18T11:35:07Z","timestamp":1637235307000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12017-011-8143-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2,3]]},"references-count":91,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["8143"],"URL":"https:\/\/doi.org\/10.1007\/s12017-011-8143-0","relation":{},"ISSN":["1535-1084","1559-1174"],"issn-type":[{"value":"1535-1084","type":"print"},{"value":"1559-1174","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,2,3]]}}}