{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T04:24:45Z","timestamp":1790223885046,"version":"4.1.0"},"reference-count":66,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2023,2,6]],"date-time":"2023-02-06T00:00:00Z","timestamp":1675641600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,2,6]],"date-time":"2023-02-06T00:00:00Z","timestamp":1675641600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100003787","name":"Natural Science foundation of Hebei Province","doi-asserted-by":"crossref","award":["H2021110004"],"award-info":[{"award-number":["H2021110004"]}],"id":[{"id":"10.13039\/501100003787","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81701296"],"award-info":[{"award-number":["81701296"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science foundation of China","doi-asserted-by":"crossref","award":["82171455"],"award-info":[{"award-number":["82171455"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neuromol Med"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1007\/s12017-023-08737-2","type":"journal-article","created":{"date-parts":[[2023,2,6]],"date-time":"2023-02-06T16:04:44Z","timestamp":1675699484000},"page":"336-349","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Spautin-1 Protects Against Mild TBI-Induced Anxiety-Like Behavior in Mice via Immunologically Silent Apoptosis"],"prefix":"10.1007","volume":"25","author":[{"given":"Hui-Tao","family":"Miao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong-Xin","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Xin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu-Ying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Meng","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na-Na","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-You","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Xue","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2933-7227","authenticated-orcid":false,"given":"Li-Min","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,2,6]]},"reference":[{"key":"8737_CR1","doi-asserted-by":"publisher","first-page":"745288","DOI":"10.3389\/fnbeh.2021.745288","volume":"15","author":"KM Alonge","year":"2021","unstructured":"Alonge, K. M., Herbert, M. J., Yagi, M., Cook, D. G., Banks, W. A., & Logsdon, A. F. (2021). Changes in brain matrix glycan sulfation associate with reactive gliosis and motor coordination in mice with head trauma. Frontier in Behavioral Neuroscience, 15, 745288. https:\/\/doi.org\/10.3389\/fnbeh.2021.745288","journal-title":"Frontier in Behavioral Neuroscience"},{"key":"8737_CR2","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1016\/j.freeradbiomed.2013.09.006","volume":"65","author":"GA Benavides","year":"2013","unstructured":"Benavides, G. A., Liang, Q., Dodson, M., Darley-Usmar, V., & Zhang, J. (2013). Inhibition of autophagy and glycolysis by nitric oxide during hypoxia-reoxygenation impairs cellular bioenergetics and promotes cell death in primary neurons. Free Radical Biology & Medicine, 65, 1215\u20131228. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2013.09.006","journal-title":"Free Radical Biology & Medicine"},{"issue":"1\u20133","key":"8737_CR3","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.schres.2014.12.040","volume":"167","author":"S Berretta","year":"2015","unstructured":"Berretta, S., Pantazopoulos, H., Markota, M., Brown, C., & Batzianouli, E. T. (2015). Losing the sugar coating: Potential impact of perineuronal net abnormalities on interneurons in schizophrenia. Schizophrenia Research, 167(1\u20133), 18\u201327. https:\/\/doi.org\/10.1016\/j.schres.2014.12.040","journal-title":"Schizophrenia Research"},{"key":"8737_CR4","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1016\/j.neuropharm.2017.03.018","volume":"118","author":"JM Blacktop","year":"2017","unstructured":"Blacktop, J. M., Todd, R. P., & Sorg, B. A. (2017). Role of perineuronal nets in the anterior dorsal lateral hypothalamic area in the acquisition of cocaine-induced conditioned place preference and self-administration. Neuropharmacology, 118, 124\u2013136. https:\/\/doi.org\/10.1016\/j.neuropharm.2017.03.018","journal-title":"Neuropharmacology"},{"issue":"22","key":"8737_CR5","doi-asserted-by":"publisher","first-page":"6443","DOI":"10.1113\/jp271946","volume":"594","author":"P Bonnavion","year":"2016","unstructured":"Bonnavion, P., Mickelsen, L. E., Fujita, A., de Lecea, L., & Jackson, A. C. (2016). Hubs and spokes of the lateral hypothalamus: Cell types, circuits and behaviour. Journal of Physiology, 594(22), 6443\u20136462. https:\/\/doi.org\/10.1113\/jp271946","journal-title":"Journal of Physiology"},{"key":"8737_CR6","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20174108","author":"M Bosiacki","year":"2019","unstructured":"Bosiacki, M., G\u0105ssowska-Dobrowolska, M., Kojder, K., Fabia\u0144ska, M., Je\u017cewski, D., Gutowska, I., & Lubkowska, A. (2019). Perineuronal nets and their role in synaptic homeostasis. International Journal of Molecular Science. https:\/\/doi.org\/10.3390\/ijms20174108","journal-title":"International Journal of Molecular Science"},{"issue":"3","key":"8737_CR7","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1074\/mcp.O112.024372","volume":"12","author":"ED Crawford","year":"2013","unstructured":"Crawford, E. D., Seaman, J. E., Agard, N., Hsu, G. W., Julien, O., Mahrus, S., Nguyen, H., Shimbo, K., Yoshihara, H. A. I., Zhuang, M., & Chalkley, R. J. (2013). The degrabase: A database of proteolysis in healthy and apoptotic human cells. Molecular and Cellular Proteomics, 12(3), 813\u2013824. https:\/\/doi.org\/10.1074\/mcp.O112.024372","journal-title":"Molecular and Cellular Proteomics"},{"issue":"12","key":"8737_CR8","doi-asserted-by":"publisher","first-page":"1717","DOI":"10.1038\/onc.2009.519","volume":"29","author":"M Djavaheri-Mergny","year":"2010","unstructured":"Djavaheri-Mergny, M., Maiuri, M. C., & Kroemer, G. (2010). Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1. Oncogene, 29(12), 1717\u20131719. https:\/\/doi.org\/10.1038\/onc.2009.519","journal-title":"Oncogene"},{"issue":"4","key":"8737_CR9","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1093\/schbul\/sbv065","volume":"41","author":"KQ Do","year":"2015","unstructured":"Do, K. Q., Cuenod, M., & Hensch, T. K. (2015). Targeting oxidative stress and aberrant critical period plasticity in the developmental trajectory to schizophrenia. Schizophrenia Bulletin, 41(4), 835\u2013846. https:\/\/doi.org\/10.1093\/schbul\/sbv065","journal-title":"Schizophrenia Bulletin"},{"issue":"23","key":"8737_CR10","doi-asserted-by":"publisher","first-page":"3793","DOI":"10.1016\/j.neuron.2021.09.008","volume":"109","author":"K Duan","year":"2021","unstructured":"Duan, K., Gu, Q., Petralia, R. S., Wang, Y. X., Panja, D., Liu, X., Lehmann, M. L., Zhu, H., Zhu, J., & Li, Z. (2021). Mitophagy in the basolateral amygdala mediates increased anxiety induced by aversive social experience. Neuron, 109(23), 3793-3809.e3798. https:\/\/doi.org\/10.1016\/j.neuron.2021.09.008","journal-title":"Neuron"},{"key":"8737_CR11","doi-asserted-by":"publisher","first-page":"5214961","DOI":"10.1155\/2016\/5214961","volume":"2016","author":"E Dzyubenko","year":"2016","unstructured":"Dzyubenko, E., Gottschling, C., & Faissner, A. (2016). Neuron-Glia interactions in neural plasticity: contributions of neural extracellular matrix and perineuronal nets. Neural Plasticity, 2016, 5214961. https:\/\/doi.org\/10.1155\/2016\/5214961","journal-title":"Neural Plasticity"},{"issue":"8","key":"8737_CR12","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1038\/s41583-019-0196-3","volume":"20","author":"JW Fawcett","year":"2019","unstructured":"Fawcett, J. W., Oohashi, T., & Pizzorusso, T. (2019). The roles of perineuronal nets and the perinodal extracellular matrix in neuronal function. Nature Reviews Neuroscience, 20(8), 451\u2013465. https:\/\/doi.org\/10.1038\/s41583-019-0196-3","journal-title":"Nature Reviews Neuroscience"},{"issue":"4","key":"8737_CR13","doi-asserted-by":"publisher","first-page":"921","DOI":"10.3892\/ijmm.2016.2495","volume":"37","author":"Y Feng","year":"2016","unstructured":"Feng, Y., Cui, Y., Gao, J. L., Li, M. H., Li, R., Jiang, X. H., Tian, Y. X., Wang, K. J., Cui, C. M., & Cui, J. Z. (2016). Resveratrol attenuates neuronal autophagy and inflammatory injury by inhibiting the TLR4\/NF-\u03baB signaling pathway in experimental traumatic brain injury. International Journal of Molecular Medicine, 37(4), 921\u2013930. https:\/\/doi.org\/10.3892\/ijmm.2016.2495","journal-title":"International Journal of Molecular Medicine"},{"issue":"3","key":"8737_CR14","doi-asserted-by":"publisher","first-page":"1560","DOI":"10.1007\/s12035-022-02735-4","volume":"59","author":"C Gao","year":"2022","unstructured":"Gao, C., Chen, X., Xu, H., Guo, H., Zheng, L., Yan, Y., Ren, Z., Luo, C., Gao, Y., Wang, Z., Tao, L., & Wang, T. (2022). Restraint stress delays the recovery of neurological impairments and exacerbates brain damages through activating endoplasmic reticulum stress-mediated neurodegeneration\/autophagy\/apopotosis post moderate traumatic brain injury. Molecular Neurobiology, 59(3), 1560\u20131576. https:\/\/doi.org\/10.1007\/s12035-022-02735-4","journal-title":"Molecular Neurobiology"},{"issue":"3","key":"8737_CR15","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1111\/j.1460-9568.2010.07295.x","volume":"32","author":"OK Hassani","year":"2010","unstructured":"Hassani, O. K., Henny, P., Lee, M. G., & Jones, B. E. (2010). GABAergic neurons intermingled with orexin and MCH neurons in the lateral hypothalamus discharge maximally during sleep. European Journal of Neuroscience, 32(3), 448\u2013457. https:\/\/doi.org\/10.1111\/j.1460-9568.2010.07295.x","journal-title":"European Journal of Neuroscience"},{"issue":"12","key":"8737_CR16","doi-asserted-by":"publisher","first-page":"5509","DOI":"10.1093\/cercor\/bhw318","volume":"27","author":"TH Hsieh","year":"2017","unstructured":"Hsieh, T. H., Lee, H. H. C., Hameed, M. Q., Pascual-Leone, A., Hensch, T. K., & Rotenberg, A. (2017). Trajectory of parvalbumin cell impairment and loss of cortical inhibition in traumatic brain injury. Cerebral Cortex, 27(12), 5509\u20135524. https:\/\/doi.org\/10.1093\/cercor\/bhw318","journal-title":"Cerebral Cortex"},{"issue":"9","key":"8737_CR17","doi-asserted-by":"publisher","first-page":"1814","DOI":"10.1007\/s11064-018-2597-5","volume":"43","author":"SX Huang","year":"2018","unstructured":"Huang, S. X., Qiu, G., Cheng, F. R., Pei, Z., Yang, Z., Deng, X. H., Zhu, J. H., Chen, L., Chen, C. C., Lin, W. F., Liu, Y., Liu, Z., & Zhu, F. Q. (2018). Berberine protects secondary injury in mice with traumatic brain injury through anti-oxidative and anti-inflammatory modulation. Neurochemical Research, 43(9), 1814\u20131825. https:\/\/doi.org\/10.1007\/s11064-018-2597-5","journal-title":"Neurochemical Research"},{"issue":"3","key":"8737_CR18","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1080\/15548627.2019.1630222","volume":"16","author":"S Jung","year":"2020","unstructured":"Jung, S., Choe, S., Woo, H., Jeong, H., An, H. K., Moon, H., Ryu, H. Y., Yeo, B. K., Lee, Y. W., Choi, H., Mun, J. Y., Sun, W., Choe, H. K., Kim, E. K., & Yu, S. W. (2020). Autophagic death of neural stem cells mediates chronic stress-induced decline of adult hippocampal neurogenesis and cognitive deficits. Autophagy, 16(3), 512\u2013530. https:\/\/doi.org\/10.1080\/15548627.2019.1630222","journal-title":"Autophagy"},{"issue":"4","key":"8737_CR19","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1038\/cdd.2010.191","volume":"18","author":"R Kang","year":"2011","unstructured":"Kang, R., Zeh, H. J., Lotze, M. T., & Tang, D. (2011). The Beclin 1 network regulates autophagy and apoptosis. Cell Death and Differentiation, 18(4), 571\u2013580. https:\/\/doi.org\/10.1038\/cdd.2010.191","journal-title":"Cell Death and Differentiation"},{"issue":"4","key":"8737_CR20","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1113\/jphysiol.2012.243493","volume":"591","author":"MM Karnani","year":"2013","unstructured":"Karnani, M. M., Szab\u00f3, G., Erd\u00e9lyi, F., & Burdakov, D. (2013). Lateral hypothalamic GAD65 neurons are spontaneously firing and distinct from orexin- and melanin-concentrating hormone neurons. Journal of Physiology, 591(4), 933\u2013953. https:\/\/doi.org\/10.1113\/jphysiol.2012.243493","journal-title":"Journal of Physiology"},{"issue":"7561","key":"8737_CR21","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1038\/nature14658","volume":"523","author":"A Kondo","year":"2015","unstructured":"Kondo, A., Shahpasand, K., Mannix, R., Qiu, J., Moncaster, J., Chen, C. H., Yao, Y., Lin, Y. M., Driver, J. A., Sun, Y., Wei, S., Luo, M. L., Albayram, O., Huang, P., Rotenberg, A., Ryo, A., Goldstein, L. E., Pascual-Leone, A., Mckee, A. C., \u2026 Lu, K. P. (2015). Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy. Nature, 523(7561), 431\u2013436. https:\/\/doi.org\/10.1038\/nature14658","journal-title":"Nature"},{"issue":"1","key":"8737_CR22","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1038\/sj.cdd.4402060","volume":"14","author":"S Kumar","year":"2007","unstructured":"Kumar, S. (2007). Caspase function in programmed cell death. Cell Death and Differentiation, 14(1), 32\u201343. https:\/\/doi.org\/10.1038\/sj.cdd.4402060","journal-title":"Cell Death and Differentiation"},{"key":"8737_CR23","doi-asserted-by":"publisher","first-page":"104842","DOI":"10.1016\/j.neuint.2020.104842","volume":"140","author":"Y Li","year":"2020","unstructured":"Li, Y., Zhang, L. M., Zhang, D. X., Zheng, W. C., Bai, Y., Bai, J., Fu, L., & Wang, X. P. (2020). CORM-3 ameliorates neurodegeneration in the amygdala and improves depression- and anxiety-like behavior in a rat model of combined traumatic brain injury and hemorrhagic shock. Neurochemistry International, 140, 104842. https:\/\/doi.org\/10.1016\/j.neuint.2020.104842","journal-title":"Neurochemistry International"},{"issue":"1","key":"8737_CR24","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1186\/s13046-019-1165-4","volume":"38","author":"Y Liao","year":"2019","unstructured":"Liao, Y., Guo, Z., Xia, X., Liu, Y., Huang, C., Jiang, L., Wang, X., Liu, J., & Huang, H. (2019). Inhibition of EGFR signaling with Spautin-1 represents a novel therapeutics for prostate cancer. Journal of Experimental & Clinical Cancer Research, 38(1), 157. https:\/\/doi.org\/10.1186\/s13046-019-1165-4","journal-title":"Journal of Experimental & Clinical Cancer Research"},{"issue":"3","key":"8737_CR25","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1073\/pnas.1409563112","volume":"112","author":"EY Liu","year":"2015","unstructured":"Liu, E. Y., Xu, N., O\u2019Prey, J., Lao, L. Y., Joshi, S., Long, J. S., O\u2019Prey, M., Croft, D. R., Beaumatin, F., Baudot, A. D., Mrschtik, M., Rosenfeldt, M., Zhang, Y., Gillespie, D. A., & Ryan, K. M. (2015). Loss of autophagy causes a synthetic lethal deficiency in DNA repair. Proceedings of the National Academy of Sciences of the United States of America, 112(3), 773\u2013778. https:\/\/doi.org\/10.1073\/pnas.1409563112","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"11","key":"8737_CR26","doi-asserted-by":"publisher","first-page":"5060","DOI":"10.1111\/jcmm.16483","volume":"25","author":"H Liu","year":"2021","unstructured":"Liu, H., Zhao, Z., Wu, T., Zhang, Q., Lu, F., Gu, J., Jiang, T., & Xue, J. (2021). Inhibition of autophagy-dependent pyroptosis attenuates cerebral ischaemia\/reperfusion injury. Journal of Cellular and Molecular Medicine, 25(11), 5060\u20135069. https:\/\/doi.org\/10.1111\/jcmm.16483","journal-title":"Journal of Cellular and Molecular Medicine"},{"issue":"1","key":"8737_CR27","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.cell.2011.08.037","volume":"147","author":"J Liu","year":"2011","unstructured":"Liu, J., Xia, H., Kim, M., Xu, L., Li, Y., Zhang, L., Cai, Y., Norberg, H. V., Zhang, T., Furuya, T., Jin, M., Zhu, Z., Wang, H., Yu, J., Li, Y., Hao, Y., Chio, A., Ke, H., Ma, D., & Yuan, J. (2011). Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13. Cell, 147(1), 223\u2013234. https:\/\/doi.org\/10.1016\/j.cell.2011.08.037","journal-title":"Cell"},{"key":"8737_CR28","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.neuroscience.2011.03.021","volume":"184","author":"CL Luo","year":"2011","unstructured":"Luo, C. L., Li, B. X., Li, Q. Q., Chen, X. P., Sun, Y. X., Bao, H. J., Dai, D. K., Shen, Y. W., Xu, H. F., Ni, H., Wan, L., Qin, Z. H., Tao, L. Y., & Zhao, Z. Q. (2011). Autophagy is involved in traumatic brain injury-induced cell death and contributes to functional outcome deficits in mice. Neuroscience, 184, 54\u201363. https:\/\/doi.org\/10.1016\/j.neuroscience.2011.03.021","journal-title":"Neuroscience"},{"issue":"7","key":"8737_CR29","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1089\/neu.2014.3504","volume":"32","author":"S Mallya","year":"2015","unstructured":"Mallya, S., Sutherland, J., Pongracic, S., Mainland, B., & Ornstein, T. J. (2015). The manifestation of anxiety disorders after traumatic brain injury: A review. Journal of Neurotrauma, 32(7), 411\u2013421. https:\/\/doi.org\/10.1089\/neu.2014.3504","journal-title":"Journal of Neurotrauma"},{"issue":"4","key":"8737_CR30","doi-asserted-by":"publisher","first-page":"a008656","DOI":"10.1101\/cshperspect.a008656","volume":"5","author":"DR McIlwain","year":"2013","unstructured":"McIlwain, D. R., Berger, T., & Mak, T. W. (2013). Caspase functions in cell death and disease. Cold Spring Harbor Perspectives in Biology, 5(4), a008656. https:\/\/doi.org\/10.1101\/cshperspect.a008656","journal-title":"Cold Spring Harbor Perspectives in Biology"},{"issue":"12","key":"8737_CR31","doi-asserted-by":"publisher","first-page":"1011","DOI":"10.1016\/j.biopsych.2019.02.021","volume":"85","author":"S Murthy","year":"2019","unstructured":"Murthy, S., Kane, G. A., Katchur, N. J., Lara Mejia, P. S., Obiofuma, G., Buschman, T. J., McEwen, B. C., & Gould, E. (2019). Perineuronal nets, inhibitory interneurons, and anxiety-related ventral hippocampal neuronal oscillations are altered by early life adversity. Biological Psychiatry, 85(12), 1011\u20131020. https:\/\/doi.org\/10.1016\/j.biopsych.2019.02.021","journal-title":"Biological Psychiatry"},{"issue":"1","key":"8737_CR32","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.molcel.2019.02.013","volume":"74","author":"X Ning","year":"2019","unstructured":"Ning, X., Wang, Y., Jing, M., Sha, M., Lv, M., Gao, P., Zhang, R., Huang, X., Feng, J. M., & Jiang, Z. (2019). Apoptotic caspases suppress Type I interferon production via the cleavage of cGAS, MAVS, and IRF3. Molecular Cell, 74(1), 19-31.e17. https:\/\/doi.org\/10.1016\/j.molcel.2019.02.013","journal-title":"Molecular Cell"},{"key":"8737_CR33","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1186\/1756-6606-6-43","volume":"6","author":"K Ohira","year":"2013","unstructured":"Ohira, K., Takeuchi, R., Iwanaga, T., & Miyakawa, T. (2013). Chronic fluoxetine treatment reduces parvalbumin expression and perineuronal nets in gamma-aminobutyric acidergic interneurons of the frontal cortex in adult mice. Molecular Brain, 6, 43. https:\/\/doi.org\/10.1186\/1756-6606-6-43","journal-title":"Molecular Brain"},{"issue":"13","key":"8737_CR34","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.1089\/neu.2013.3255","volume":"31","author":"AL Petraglia","year":"2014","unstructured":"Petraglia, A. L., Plog, B. A., Dayawansa, S., Chen, M., Dashnaw, M. L., Czerniecka, K., Walker, C. T., Viterise, T., Hyrien, O., Iliff, J. J., Deane, R., Nedergaard, M., & Huang, J. H. (2014). The spectrum of neurobehavioral sequelae after repetitive mild traumatic brain injury: A novel mouse model of chronic traumatic encephalopathy. Journal of Neurotrauma, 31(13), 1211\u20131224. https:\/\/doi.org\/10.1089\/neu.2013.3255","journal-title":"Journal of Neurotrauma"},{"issue":"3","key":"8737_CR35","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1016\/j.pnpbp.2007.11.023","volume":"32","author":"MH Pollack","year":"2008","unstructured":"Pollack, M. H., Jensen, J. E., Simon, N. M., Kaufman, R. E., & Renshaw, P. F. (2008). High-field MRS study of GABA, glutamate and glutamine in social anxiety disorder: Response to treatment with levetiracetam. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 32(3), 739\u2013743. https:\/\/doi.org\/10.1016\/j.pnpbp.2007.11.023","journal-title":"Progress in Neuro-Psychopharmacology and Biological Psychiatry"},{"issue":"2","key":"8737_CR36","doi-asserted-by":"publisher","first-page":"240","DOI":"10.4161\/auto.7.2.14286","volume":"7","author":"M Pozuelo-Rubio","year":"2011","unstructured":"Pozuelo-Rubio, M. (2011). 14\u20133-3\u03b6 binds class III phosphatidylinositol-3-kinase and inhibits autophagy. Autophagy, 7(2), 240\u2013242. https:\/\/doi.org\/10.4161\/auto.7.2.14286","journal-title":"Autophagy"},{"issue":"7","key":"8737_CR37","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1016\/j.tins.2019.04.003","volume":"42","author":"AC Reichelt","year":"2019","unstructured":"Reichelt, A. C., Hare, D. J., Bussey, T. J., & Saksida, L. M. (2019). Perineuronal nets: Plasticity, protection, and therapeutic potential. Trends in Neurosciences, 42(7), 458\u2013470. https:\/\/doi.org\/10.1016\/j.tins.2019.04.003","journal-title":"Trends in Neurosciences"},{"issue":"6","key":"8737_CR38","doi-asserted-by":"publisher","first-page":"E29","DOI":"10.1097\/htr.0000000000000294","volume":"32","author":"D Ren","year":"2017","unstructured":"Ren, D., Fan, J., Puccio, A. M., Okonkwo, D. O., Beers, S. R., & Conley, Y. (2017). Group-based trajectory analysis of emotional symptoms among survivors after severe traumatic brain injury. The Journal of Head Trauma Rehabilitation, 32(6), E29-e37. https:\/\/doi.org\/10.1097\/htr.0000000000000294","journal-title":"The Journal of Head Trauma Rehabilitation"},{"key":"8737_CR39","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aai8753","author":"D Riga","year":"2017","unstructured":"Riga, D., Kramvis, I., Koskinen, M. K., van Bokhoven, P., van der Harst, J. E., Heistek, T. S., Timmerman, A. J., Nierop, P., Schors, R. C., Pieneman, A. W., Weger, A., Mourik, Y., Schoffelmeer, A. N. M., Mansvelder, H. D., Meredith, R. M., Hoogendijk, W. J. G., Smit, A. B., & Spijker, S. (2017). Hippocampal extracellular matrix alterations contribute to cognitive impairment associated with a chronic depressive-like state in rats. Science Translational Medicine. https:\/\/doi.org\/10.1126\/scitranslmed.aai8753","journal-title":"Science Translational Medicine"},{"issue":"7","key":"8737_CR40","doi-asserted-by":"publisher","first-page":"1563","DOI":"10.1016\/j.cell.2014.11.037","volume":"159","author":"A Rongvaux","year":"2014","unstructured":"Rongvaux, A., Jackson, R., Harman, C. C., Li, T., West, A. P., de Zoete, M. R., Wu, Y., Yordy, B., Lakhani, S. A., Kuan, C. Y., Taniguchi, T., Shadel, G. S., Chen, Z. J., Iwasaki, A., & Flavell, R. A. (2014). Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA. Cell, 159(7), 1563\u20131577. https:\/\/doi.org\/10.1016\/j.cell.2014.11.037","journal-title":"Cell"},{"issue":"4","key":"8737_CR41","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1002\/cne.10860","volume":"465","author":"DL Rosin","year":"2003","unstructured":"Rosin, D. L., Weston, M. C., Sevigny, C. P., Stornetta, R. L., & Guyenet, P. G. (2003). Hypothalamic orexin (hypocretin) neurons express vesicular glutamate transporters VGLUT1 or VGLUT2. The Journal of Comparative Neurology, 465(4), 593\u2013603. https:\/\/doi.org\/10.1002\/cne.10860","journal-title":"The Journal of Comparative Neurology"},{"issue":"4","key":"8737_CR42","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1530\/ec-16-0031","volume":"5","author":"RK Rowe","year":"2016","unstructured":"Rowe, R. K., Rumney, B. M., May, H. G., Permana, P., Adelson, P. D., Harman, S. M., Lifshitz, J., & Thomas, T. C. (2016). Diffuse traumatic brain injury affects chronic corticosterone function in the rat. Endocrine Connections, 5(4), 152\u2013166. https:\/\/doi.org\/10.1530\/ec-16-0031","journal-title":"Endocrine Connections"},{"issue":"16","key":"8737_CR43","doi-asserted-by":"publisher","first-page":"2647","DOI":"10.1002\/cne.24522","volume":"526","author":"AN Santiago","year":"2018","unstructured":"Santiago, A. N., Lim, K. Y., Opendak, M., Sullivan, R. M., & Aoki, C. (2018). Early life trauma increases threat response of peri-weaning rats, reduction of axo-somatic synapses formed by parvalbumin cells and perineuronal net in the basolateral nucleus of amygdala. The Journal of Comparative Neurology, 526(16), 2647\u20132664. https:\/\/doi.org\/10.1002\/cne.24522","journal-title":"The Journal of Comparative Neurology"},{"issue":"2","key":"8737_CR44","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1523\/jneurosci.0718-19.2019","volume":"40","author":"T Sen","year":"2020","unstructured":"Sen, T., Saha, P., Gupta, R., Foley, L. M., Jiang, T., Abakumova, O. S., Hitchens, T. K., & Sen, N. (2020). Aberrant ER stress induced neuronal-IFN\u03b2 elicits white matter injury due to microglial activation and T-cell infiltration after TBI. Journal of Neuroscience, 40(2), 424\u2013446. https:\/\/doi.org\/10.1523\/jneurosci.0718-19.2019","journal-title":"Journal of Neuroscience"},{"issue":"10","key":"8737_CR45","doi-asserted-by":"publisher","first-page":"1440","DOI":"10.1038\/mp.2016.118","volume":"22","author":"JS Seo","year":"2017","unstructured":"Seo, J. S., Wei, J., Qin, L., Kim, Y., Yan, Z., & Greengard, P. (2017). Cellular and molecular basis for stress-induced depression. Molecular Psychiatry, 22(10), 1440\u20131447. https:\/\/doi.org\/10.1038\/mp.2016.118","journal-title":"Molecular Psychiatry"},{"issue":"5","key":"8737_CR46","doi-asserted-by":"publisher","first-page":"1661","DOI":"10.3892\/ijo.2014.2313","volume":"44","author":"S Shao","year":"2014","unstructured":"Shao, S., Li, S., Qin, Y., Wang, X., Yang, Y., Bai, H., Zhou, L., Zhao, C., & Wang, C. (2014). Spautin-1, a novel autophagy inhibitor, enhances imatinib-induced apoptosis in chronic myeloid leukemia. International Journal of Oncology, 44(5), 1661\u20131668. https:\/\/doi.org\/10.3892\/ijo.2014.2313","journal-title":"International Journal of Oncology"},{"issue":"52","key":"8737_CR47","doi-asserted-by":"publisher","first-page":"27063","DOI":"10.1073\/pnas.1902680116","volume":"116","author":"W Shi","year":"2019","unstructured":"Shi, W., Wei, X., Wang, X., Du, S., Liu, W., Song, J., & Wang, Y. (2019). Perineuronal nets protect long-term memory by limiting activity-dependent inhibition from parvalbumin interneurons. Proceedings of the National Academy of Sciences of the United States of America, 116(52), 27063\u201327073. https:\/\/doi.org\/10.1073\/pnas.1902680116","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"7","key":"8737_CR48","doi-asserted-by":"publisher","first-page":"e2104112","DOI":"10.1002\/advs.202104112","volume":"9","author":"Y Shi","year":"2022","unstructured":"Shi, Y., Wu, X., Zhou, J., Cui, W., Wang, J., Hu, Q., Zhang, S., Han, L., Zhou, M., Luo, J., Wang, Q., Liu, H., Feng, S., & Qu, Y. (2022). Single-nucleus RNA sequencing reveals that decorin expression in the amygdala regulates perineuronal nets expression and fear conditioning response after traumatic brain injury. Advanced Science (weinh), 9(7), e2104112. https:\/\/doi.org\/10.1002\/advs.202104112","journal-title":"Advanced Science (weinh)"},{"issue":"22","key":"8737_CR49","doi-asserted-by":"publisher","first-page":"2381","DOI":"10.1089\/neu.2018.6149","volume":"37","author":"SR Shultz","year":"2020","unstructured":"Shultz, S. R., McDonald, S. J., Corrigan, F., Semple, B. D., Salberg, S., Zamani, A., Jones, N. C., & Mychasiuk, R. (2020). Clinical relevance of behavior testing in animal models of traumatic brain injury. Journal of Neurotrauma, 37(22), 2381\u20132400. https:\/\/doi.org\/10.1089\/neu.2018.6149","journal-title":"Journal of Neurotrauma"},{"issue":"11","key":"8737_CR50","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1038\/sj.cdd.4400601","volume":"6","author":"EA Slee","year":"1999","unstructured":"Slee, E. A., Adrain, C., & Martin, S. J. (1999). Serial killers: Ordering caspase activation events in apoptosis. Cell Death and Differentiation, 6(11), 1067\u20131074. https:\/\/doi.org\/10.1038\/sj.cdd.4400601","journal-title":"Cell Death and Differentiation"},{"key":"8737_CR51","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.66491","author":"SR Stevens","year":"2021","unstructured":"Stevens, S. R., Longley, C. M., Ogawa, Y., Teliska, L. H., Arumanayagam, A. S., Nair, S., Oses-Prieto, J. A., Burlingame, A. L., Cykowski, M. D., Xue, M., & Rasband, M. N. (2021). Ankyrin-R regulates fast-spiking interneuron excitability through perineuronal nets and Kv3.1b K(+) channels. eLife. https:\/\/doi.org\/10.7554\/eLife.66491","journal-title":"eLife"},{"issue":"4","key":"8737_CR52","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1016\/j.chembiol.2017.03.009","volume":"24","author":"CY Taabazuing","year":"2017","unstructured":"Taabazuing, C. Y., Okondo, M. C., & Bachovchin, D. A. (2017). Pyroptosis and apoptosis pathways engage in bidirectional crosstalk in monocytes and macrophages. Cell Chemical Biology, 24(4), 507-514.e504. https:\/\/doi.org\/10.1016\/j.chembiol.2017.03.009","journal-title":"Cell Chemical Biology"},{"key":"8737_CR53","doi-asserted-by":"publisher","first-page":"115261","DOI":"10.1016\/j.taap.2020.115261","volume":"408","author":"Q Tian","year":"2020","unstructured":"Tian, Q., Fan, X., Ma, J., Han, Y., Li, D., Jiang, S., Zhang, F., Guang, H., Shan, X., Chen, R., Wang, P., Wang, Q., Yang, J., Wang, Y., Hu, L., Shentu, Y., & Gong, Y. (2020). Resveratrol ameliorates lipopolysaccharide-induced anxiety-like behavior by attenuating YAP-mediated neuro-inflammation and promoting hippocampal autophagy in mice. Toxicology and Applied Pharmacology, 408, 115261. https:\/\/doi.org\/10.1016\/j.taap.2020.115261","journal-title":"Toxicology and Applied Pharmacology"},{"issue":"1","key":"8737_CR54","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1111\/cpr.12154","volume":"48","author":"XP Tong","year":"2015","unstructured":"Tong, X. P., Chen, Y., Zhang, S. Y., Xie, T., Tian, M., Guo, M. R., Kasimu, R., Ouyang, L., & Wang, J. H. (2015). Key autophagic targets and relevant small-molecule compounds in cancer therapy. Cell Proliferation, 48(1), 7\u201316. https:\/\/doi.org\/10.1111\/cpr.12154","journal-title":"Cell Proliferation"},{"issue":"21","key":"8737_CR55","doi-asserted-by":"publisher","first-page":"e0040621","DOI":"10.1128\/jvi.00406-21","volume":"95","author":"A Tripathi","year":"2021","unstructured":"Tripathi, A., Singh Rawat, B., Addya, S., Surjit, M., Tailor, P., Vrati, S., & Banerjee, A. (2021). Lack of Interferon (IFN) regulatory factor 8 associated with restricted IFN-\u03b3 response augmented Japanese encephalitis virus replication in the mouse brain. Journal of Virology, 95(21), e0040621. https:\/\/doi.org\/10.1128\/jvi.00406-21","journal-title":"Journal of Virology"},{"issue":"4","key":"8737_CR56","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1089\/neu.2007.0452","volume":"25","author":"J Tsenter","year":"2008","unstructured":"Tsenter, J., Beni-Adani, L., Assaf, Y., Alexandrovich, A. G., Trembovler, V., & Shohami, E. (2008). Dynamic changes in the recovery after traumatic brain injury in mice: Effect of injury severity on T2-weighted MRI abnormalities, and motor and cognitive functions. Journal of Neurotrauma, 25(4), 324\u2013333. https:\/\/doi.org\/10.1089\/neu.2007.0452","journal-title":"Journal of Neurotrauma"},{"issue":"4","key":"8737_CR57","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1016\/s0896-6273(04)00251-x","volume":"42","author":"AN van den Pol","year":"2004","unstructured":"van den Pol, A. N., Acuna-Goycolea, C., Clark, K. R., & Ghosh, P. K. (2004). Physiological properties of hypothalamic MCH neurons identified with selective expression of reporter gene after recombinant virus infection. Neuron, 42(4), 635\u2013652. https:\/\/doi.org\/10.1016\/s0896-6273(04)00251-x","journal-title":"Neuron"},{"issue":"1","key":"8737_CR58","doi-asserted-by":"publisher","first-page":"109313","DOI":"10.1016\/j.celrep.2021.109313","volume":"36","author":"A Venturino","year":"2021","unstructured":"Venturino, A., Schulz, R., De Jes\u00fas-Cort\u00e9s, H., Maes, M. E., Nagy, B., Reilly-And\u00fajar, F., Colombo, G., Cubero, R. J. A., Uiterkamp, F. E. S., Bear, M. F., & Siegert, S. (2021). Microglia enable mature perineuronal nets disassembly upon anesthetic ketamine exposure or 60-Hz light entrainment in the healthy brain. Cell Reports, 36(1), 109313. https:\/\/doi.org\/10.1016\/j.celrep.2021.109313","journal-title":"Cell Reports"},{"key":"8737_CR59","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1016\/j.jconrel.2020.02.042","volume":"321","author":"X Wang","year":"2020","unstructured":"Wang, X., Yin, S., Li, M., Rao, J., Wan, D., Qiu, Y., Yu, Q., Chen, X., Lu, Z., Long, Y., Zhang, Z., & He, Q. (2020). Autophagy inhibition changes the disposition of non-viral gene carriers during blood-brain barrier penetration and enhances TRAIL-induced apoptosis in brain metastatic tumor. Journal of Controlled Release, 321, 497\u2013508. https:\/\/doi.org\/10.1016\/j.jconrel.2020.02.042","journal-title":"Journal of Controlled Release"},{"issue":"1","key":"8737_CR60","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1093\/bja\/aem131","volume":"99","author":"C Werner","year":"2007","unstructured":"Werner, C., & Engelhard, K. (2007). Pathophysiology of traumatic brain injury. British Journal of Anaesthesia, 99(1), 4\u20139. https:\/\/doi.org\/10.1093\/bja\/aem131","journal-title":"British Journal of Anaesthesia"},{"issue":"7","key":"8737_CR61","doi-asserted-by":"publisher","first-page":"1549","DOI":"10.1016\/j.cell.2014.11.036","volume":"159","author":"MJ White","year":"2014","unstructured":"White, M. J., McArthur, K., Metcalf, D., Lane, R. M., Cambier, J. C., Herold, M. J., Delft, M. F., Bedoui, S., Lessene, G., Richie, M. E., Huang, D. C. S., & Kile, B. T. (2014). Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production. Cell, 159(7), 1549\u20131562. https:\/\/doi.org\/10.1016\/j.cell.2014.11.036","journal-title":"Cell"},{"issue":"20","key":"8737_CR62","doi-asserted-by":"publisher","first-page":"1866","DOI":"10.1089\/neu.2015.4272","volume":"33","author":"CA Wiley","year":"2016","unstructured":"Wiley, C. A., Bissel, S. J., Lesniak, A., Dixon, C. E., Franks, J., Beer Stolz, D., Sun, M., Wang, G., Switzer, R., Kochanek, P. M., & Murdoch, G. (2016). Ultrastructure of diaschisis lesions after traumatic brain injury. Journal of Neurotrauma, 33(20), 1866\u20131882. https:\/\/doi.org\/10.1089\/neu.2015.4272","journal-title":"Journal of Neurotrauma"},{"issue":"6","key":"8737_CR63","doi-asserted-by":"publisher","first-page":"1352","DOI":"10.1016\/j.neuron.2016.11.018","volume":"92","author":"WZ Yang","year":"2016","unstructured":"Yang, W. Z., Liu, T. T., Cao, J. W., Chen, X. F., Liu, X., Wang, M., Su, X., Zhang, S. Q., Qiu, B. L., Hu, W. X., Liu, L. Y., Ma, L., & Yu, Y. C. (2016). Fear erasure facilitated by immature inhibitory neuron transplantation. Neuron, 92(6), 1352\u20131367. https:\/\/doi.org\/10.1016\/j.neuron.2016.11.018","journal-title":"Neuron"},{"issue":"7","key":"8737_CR64","doi-asserted-by":"publisher","first-page":"1214","DOI":"10.1080\/15548627.2018.1460010","volume":"14","author":"SK Yeo","year":"2018","unstructured":"Yeo, S. K., Paul, R., Haas, M., Wang, C., & Guan, J. L. (2018). Improved efficacy of mitochondrial disrupting agents upon inhibition of autophagy in a mouse model of BRCA1-deficient breast cancer. Autophagy, 14(7), 1214\u20131225. https:\/\/doi.org\/10.1080\/15548627.2018.1460010","journal-title":"Autophagy"},{"key":"8737_CR65","doi-asserted-by":"publisher","first-page":"113683","DOI":"10.1016\/j.expneurol.2021.113683","volume":"341","author":"LM Zhang","year":"2021","unstructured":"Zhang, L. M., Zhang, D. X., Zheng, W. C., Hu, J. S., Fu, L., Li, Y., Xin, Y., & Wang, X. P. (2021). CORM-3 exerts a neuroprotective effect in a rodent model of traumatic brain injury via the bidirectional gut-brain interactions. Experimental Neurology, 341, 113683. https:\/\/doi.org\/10.1016\/j.expneurol.2021.113683","journal-title":"Experimental Neurology"},{"issue":"1","key":"8737_CR66","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1186\/s12868-019-0545-1","volume":"20","author":"N Zhou","year":"2019","unstructured":"Zhou, N., Wei, Z. X., & Qi, Z. X. (2019). Inhibition of autophagy triggers melatonin-induced apoptosis in glioblastoma cells. BMC Neuroscience, 20(1), 63. https:\/\/doi.org\/10.1186\/s12868-019-0545-1","journal-title":"BMC Neuroscience"}],"container-title":["NeuroMolecular Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12017-023-08737-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12017-023-08737-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12017-023-08737-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,21]],"date-time":"2023-09-21T12:19:15Z","timestamp":1695298755000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12017-023-08737-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,6]]},"references-count":66,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["8737"],"URL":"https:\/\/doi.org\/10.1007\/s12017-023-08737-2","relation":{},"ISSN":["1535-1084","1559-1174"],"issn-type":[{"value":"1535-1084","type":"print"},{"value":"1559-1174","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,6]]},"assertion":[{"value":"4 December 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 January 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 February 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest, or non-financial competing interest in the subject matter or materials discussed in this manuscript by any of the authors.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not Applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}}]}}