{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T16:45:30Z","timestamp":1764002730558,"version":"3.32.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neuromol Med"],"DOI":"10.1007\/s12017-024-08799-w","type":"journal-article","created":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T19:02:34Z","timestamp":1722538954000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of Neuroprotective Effect of Gut Microbe in Parkinson's Disease: An In Silico and In Vivo Approach"],"prefix":"10.1007","volume":"26","author":[{"given":"Kanika","family":"Bhardwaj","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9047-4290","authenticated-orcid":false,"given":"Neelu Kanwar","family":"Rajawat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nupur","family":"Mathur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aviral","family":"Kaushik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,8,1]]},"reference":[{"key":"8799_CR1","first-page":"671","volume":"2","author":"H Aebi","year":"1974","unstructured":"Aebi, H. (1974). Catalase. Methods in Enzymatic Analysis, 2, 671\u2013678.","journal-title":"Methods in Enzymatic Analysis"},{"issue":"5","key":"8799_CR2","doi-asserted-by":"publisher","first-page":"4608","DOI":"10.1021\/acsomega.2c05837","volume":"8","author":"KM Alharthy","year":"2023","unstructured":"Alharthy, K. M., Althurwi, H. N., Albaqami, F. F., Altharawi, A., Alzarea, S. I., Al-Abbasi, F. A., Nadeem, M. S., & Kazmi, I. (2023). Barbigerone potentially alleviates rotenone-activated Parkinson\u2019s disease in a rodent model by reducing oxidative stress and neuroinflammatory cytokines. ACS Omega, 8(5), 4608\u20134615.","journal-title":"ACS Omega"},{"issue":"1","key":"8799_CR3","doi-asserted-by":"publisher","first-page":"37","DOI":"10.4103\/ijp.ijp_325_23","volume":"56","author":"K Bhardwaj","year":"2024","unstructured":"Bhardwaj, K., Rajawat, N. K., & Mathur, N. (2024). Development of Alpha-Synuclein protein model against therapeutic aspects of Parkinson\u2019s disease. Indian Journal of Pharmacology, 56(1), 37\u201341. https:\/\/doi.org\/10.4103\/ijp.ijp_325_23","journal-title":"Indian Journal of Pharmacology"},{"issue":"3","key":"8799_CR4","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1002\/mds.27556","volume":"34","author":"DP Breen","year":"2019","unstructured":"Breen, D. P., Halliday, G. M., & Lang, A. E. (2019). Gut\u2013brain axis and the spread of \u03b1-synuclein pathology: Vagal highway or dead end? Movement Disorders, 34(3), 307\u2013316.","journal-title":"Movement Disorders"},{"key":"8799_CR5","doi-asserted-by":"publisher","first-page":"626","DOI":"10.3389\/fnins.2018.00626","volume":"12","author":"LM Butkovich","year":"2018","unstructured":"Butkovich, L. M., Houser, M. C., & Tansey, M. G. (2018). \u03b1-Synuclein and noradrenergic modulation of immune cells in Parkinson\u2019s disease pathogenesis. Frontiers in Neuroscience, 12, 626. https:\/\/doi.org\/10.3389\/fnins.2018.00626","journal-title":"Frontiers in Neuroscience"},{"key":"8799_CR6","unstructured":"Charles, M., & McEwen, J. (1977). Methods in enzymology (Vol. XVIIB, pp. 692\u2013698). Academic."},{"issue":"10","key":"8799_CR7","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1016\/j.parkreldis.2011.02.018","volume":"17","author":"KR Chaudhuri","year":"2011","unstructured":"Chaudhuri, K. R., Odin, P., Antonini, A., & Martinez-Martin, P. (2011). Parkinson\u2019s disease: The non-motor issues. Parkinsonism and Related Disorders, 17(10), 717\u2013723.","journal-title":"Parkinsonism and Related Disorders"},{"key":"8799_CR8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12906-018-2166-0","volume":"18","author":"P Chonpathompikunlert","year":"2018","unstructured":"Chonpathompikunlert, P., Boonruamkaew, P., Sukketsiri, W., Hutamekalin, P., & Sroyraya, M. (2018). The antioxidant and neurochemical activity of Apium graveolens L. and its ameliorative effect on MPTP-induced Parkinson-like symptoms in mice. BMC Complementary and Alternative Medicine, 18, 1\u201312.","journal-title":"BMC Complementary and Alternative Medicine"},{"key":"8799_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s40478-015-0196-0","volume":"3","author":"T Clairembault","year":"2015","unstructured":"Clairembault, T., Leclair-Visonneau, L., Coron, E., Bourreille, A., Le Dily, S., Vavasseur, F., Heymann, M. F., Neunlist, M., & Derkinderen, P. (2015). Structural alterations of the intestinal epithelial barrier in Parkinson\u2019s disease. Acta Neuropathologica Communications, 3, 1\u20139.","journal-title":"Acta Neuropathologica Communications"},{"key":"8799_CR10","doi-asserted-by":"publisher","first-page":"84","DOI":"10.3389\/fnmol.2020.00084","volume":"13","author":"SH El-Ghaiesh","year":"2020","unstructured":"El-Ghaiesh, S. H., Bahr, H. I., Ibrahiem, A. T., Ghorab, D., Alomar, S. Y., Farag, N. E., & Zaitone, S. A. (2020). Metformin protects from rotenone-induced nigrostriatal neuronal death in adult mice by activating AMPK-FOXO3 signaling and mitigation of angiogenesis. Frontiers in Molecular Neuroscience, 13, 84.","journal-title":"Frontiers in Molecular Neuroscience"},{"issue":"5","key":"8799_CR11","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1111\/cns.13805","volume":"28","author":"H Fikry","year":"2022","unstructured":"Fikry, H., Saleh, L. A., & Abdel Gawad, S. (2022). Neuroprotective effects of curcumin on the cerebellum in a rotenone-induced Parkinson\u2019s disease Model. CNS Neuroscience and Therapeutics, 28(5), 732\u2013748.","journal-title":"CNS Neuroscience and Therapeutics"},{"issue":"2","key":"8799_CR12","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.bbr.2011.12.007","volume":"230","author":"KE Glajch","year":"2012","unstructured":"Glajch, K. E., Fleming, S. M., Surmeier, D. J., & Osten, P. (2012). Sensorimotor assessment of the unilateral 6-hydroxydopamine mouse model of Parkinson\u2019s disease. Behavioural Brain Research, 230(2), 309\u2013316.","journal-title":"Behavioural Brain Research"},{"issue":"8","key":"8799_CR14","doi-asserted-by":"publisher","first-page":"171","DOI":"10.22159\/ajpcr.2017.v10i8.18709","volume":"10","author":"SK Jha","year":"2017","unstructured":"Jha, S. K., & Kumar, P. (2017). An in silico study of naringenin-mediated neuroprotection in Parkinson\u2019s disease. Asian Journal of Pharmaceutical and Clinical Research, 10(8), 171\u2013176.","journal-title":"Asian Journal of Pharmaceutical and Clinical Research"},{"key":"8799_CR15","doi-asserted-by":"publisher","first-page":"9730467","DOI":"10.1155\/2016\/9730467","volume":"2016","author":"H Ju\u00e1rez Olgu\u00edn","year":"2016","unstructured":"Ju\u00e1rez Olgu\u00edn, H., Calder\u00f3n Guzm\u00e1n, D., Hern\u00e1ndez Garc\u00eda, E., & Barrag\u00e1n Mej\u00eda, G. (2016a). The role of dopamine and its dysfunction as a consequence of oxidative stress. Oxidative Medicine and Cellular Longevity, 2016, 9730467. https:\/\/doi.org\/10.1155\/2016\/9730467","journal-title":"Oxidative Medicine and Cellular Longevity"},{"key":"8799_CR16","doi-asserted-by":"publisher","first-page":"9730467","DOI":"10.1155\/2016\/9730467","volume":"2016","author":"H Ju\u00e1rez Olgu\u00edn","year":"2016","unstructured":"Ju\u00e1rez Olgu\u00edn, H., Calder\u00f3n Guzm\u00e1n, D., Hern\u00e1ndez Garc\u00eda, E., & Barrag\u00e1n Mej\u00eda, G. (2016b). The role of dopamine and its dysfunction as a consequence of oxidative stress. Oxidative Medicine and Cellular Longevity, 2016, 9730467.","journal-title":"Oxidative Medicine and Cellular Longevity"},{"issue":"11","key":"8799_CR17","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1038\/nrneurol.2015.197","volume":"11","author":"L Klingelhoefer","year":"2015","unstructured":"Klingelhoefer, L., & Reichmann, H. (2015). Pathogenesis of Parkinson disease\u2014The gut\u2013brain axis and environmental factors. Nature Reviews Neurology, 11(11), 625\u2013636.","journal-title":"Nature Reviews Neurology"},{"issue":"1","key":"8799_CR18","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","volume":"193","author":"O Lowry","year":"1951","unstructured":"Lowry, O., Rosebrough, N., Farr, A. L., & Randall, R. (1951). Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry, 193(1), 265\u2013275.","journal-title":"Journal of Biological Chemistry"},{"issue":"4","key":"8799_CR19","doi-asserted-by":"publisher","first-page":"325","DOI":"10.7546\/ijba.2022.26.4.000879","volume":"26","author":"B Lozanska","year":"2022","unstructured":"Lozanska, B., Georgieva, M., Miloshev, G., & Xenodochidis, C. (2022). Ageing and neurodegeneration\u2014The role of neurotransmitters\u2019 activity. International Journal of Bioautomation, 26(4), 325.","journal-title":"International Journal of Bioautomation"},{"key":"8799_CR20","unstructured":"Luna, L. G. (1968). Manual of histologic staining methods of the Armed Forces Institute of Pathology (pp. 12\u2013258). McGraw-Hill."},{"issue":"11","key":"8799_CR21","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0258928","volume":"16","author":"S Madiha","year":"2021","unstructured":"Madiha, S., Batool, Z., Tabassum, S., Liaquat, L., Sadir, S., Shahzad, S., Naqvi, F., Saleem, S., Yousuf, S., Nawaz, A., & Haider, S. (2021). Quercetin exhibits potent antioxidant activity, restores motor and non-motor deficits induced by rotenone toxicity. PLoS ONE, 16(11), e0258928.","journal-title":"PLoS ONE"},{"issue":"1","key":"8799_CR22","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1080\/14737175.2023.2173576","volume":"23","author":"E Mantovani","year":"2023","unstructured":"Mantovani, E., Zucchella, C., Argyriou, A. A., & Tamburin, S. (2023). Treatment for cognitive and neuropsychiatric non-motor symptoms in Parkinson\u2019s disease: Current evidence and future perspectives. Expert Review of Neurotherapeutics, 23(1), 25\u201343.","journal-title":"Expert Review of Neurotherapeutics"},{"issue":"3","key":"8799_CR23","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1016\/j.etap.2006.11.012","volume":"23","author":"YR Mao","year":"2007","unstructured":"Mao, Y. R., Jiang, L., Duan, Y. L., An, L. J., & Jiang, B. (2007). Efficacy of catalpol as protectant against oxidative stress and mitochondrial dysfunction on rotenone-induced toxicity in mice brain. Environmental Toxicology and Pharmacology, 23(3), 314\u2013318.","journal-title":"Environmental Toxicology and Pharmacology"},{"key":"8799_CR24","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/7912765","author":"AFM Monteiro","year":"2018","unstructured":"Monteiro, A. F. M., Viana, J. D. O., Nayarisseri, A., Zondegoumba, E. N., Mendon\u00e7a Junior, F. J. B., Scotti, M. T., & Scotti, L. (2018). Computational studies applied to flavonoids against Alzheimer\u2019s and Parkinson\u2019s diseases. Oxidative Medicine and Cellular Longevity. https:\/\/doi.org\/10.1155\/2018\/7912765","journal-title":"Oxidative Medicine and Cellular Longevity"},{"issue":"4","key":"8799_CR25","doi-asserted-by":"publisher","first-page":"420","DOI":"10.2174\/1573409915666190503113617","volume":"16","author":"N Mubashir","year":"2020","unstructured":"Mubashir, N., Fatima, R., & Naeem, S. (2020). Identification of novel phyto-chemicals from Ocimum basilicum for the treatment of Parkinson\u2019s disease using in silico approach. Current Computer-Aided Drug Design, 16(4), 420\u2013434.","journal-title":"Current Computer-Aided Drug Design"},{"key":"8799_CR26","doi-asserted-by":"publisher","first-page":"9613090","DOI":"10.1155\/2019\/9613090","volume":"2019","author":"A Nandi","year":"2019","unstructured":"Nandi, A., Yan, L. J., Jana, C. K., & Das, N. (2019). Role of catalase in oxidative stress- and age-associated degenerative diseases. Oxidative Medicine and Cellular Longevity, 2019, 9613090.","journal-title":"Oxidative Medicine and Cellular Longevity"},{"issue":"2","key":"8799_CR27","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","volume":"95","author":"H Ohkawa","year":"1979","unstructured":"Ohkawa, H., Ohishi, N., & Yagi, K. (1979). Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Analytical Biochemistry, 95(2), 351\u2013358.","journal-title":"Analytical Biochemistry"},{"issue":"1","key":"8799_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1752-0509-8-54","volume":"8","author":"E Ouzounoglou","year":"2014","unstructured":"Ouzounoglou, E., Kalamatianos, D., Emmanouilidou, E., Xilouri, M., Stefanis, L., Vekrellis, K., & Manolakos, E. S. (2014). In silico modeling of the effects of alpha-synuclein oligomerization on dopaminergic neuronal homeostasis. BMC Systems Biology, 8(1), 1\u201318.","journal-title":"BMC Systems Biology"},{"issue":"1","key":"8799_CR29","first-page":"158","volume":"70","author":"DE Paglia","year":"1967","unstructured":"Paglia, D. E., & Valentine, W. N. (1967). Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. The Journal of Laboratory and Clinical Medicine, 70(1), 158\u2013169.","journal-title":"The Journal of Laboratory and Clinical Medicine"},{"key":"8799_CR30","doi-asserted-by":"publisher","DOI":"10.1016\/j.mvr.2020.104010","volume":"131","author":"S Panday","year":"2020","unstructured":"Panday, S., Talreja, R., & Kavdia, M. (2020). The role of glutathione and glutathione peroxidase in regulating cellular level of reactive oxygen and nitrogen species. Microvascular Research, 131, 104010.","journal-title":"Microvascular Research"},{"key":"8799_CR31","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2021.111525","volume":"139","author":"A Pathania","year":"2021","unstructured":"Pathania, A., Kumar, R., & Sandhir, R. (2021). Hydroxytyrosol as anti-Parkinsonian molecule: Assessment using in silico and MPTP-induced Parkinson\u2019s disease model. Biomedicine and Pharmacotherapy, 139, 111525.","journal-title":"Biomedicine and Pharmacotherapy"},{"key":"8799_CR32","first-page":"1","volume":"1244","author":"H Rahman","year":"2008","unstructured":"Rahman, H., & Eswaraiah, M. (2008). Simple spectroscopic methods for estimating brain neurotransmitters, antioxidant enzymes of laboratory animals like mice: A review. Pharmatutor Art, 1244, 1\u201312.","journal-title":"Pharmatutor Art"},{"key":"8799_CR33","first-page":"A30","volume":"69","author":"NK Rajawat","year":"2022","unstructured":"Rajawat, N. K. (2022). Neurotoxicity of N-Nitrosodimethylamine (NDMA) in Swiss albino mice and neuroprotection by nanocurcumin. Materials Today: Proceedings, 69, A30\u2013A41.","journal-title":"Materials Today: Proceedings"},{"issue":"7","key":"8799_CR34","doi-asserted-by":"publisher","first-page":"1192","DOI":"10.3390\/molecules22071192","volume":"22","author":"RR Ramsay","year":"2017","unstructured":"Ramsay, R. R., & Tipton, K. F. (2017). Assessment of enzyme inhibition: A review with examples from the development of monoamine oxidase and cholinesterase inhibitory drugs. Molecules, 22(7), 1192.","journal-title":"Molecules"},{"issue":"1","key":"8799_CR35","doi-asserted-by":"publisher","first-page":"118","DOI":"10.3390\/nu3010118","volume":"3","author":"M Rossi","year":"2011","unstructured":"Rossi, M., Amaretti, A., & Raimondi, S. (2011). Folate production by probiotic bacteria. Nutrients, 3(1), 118\u2013134.","journal-title":"Nutrients"},{"issue":"17","key":"8799_CR36","doi-asserted-by":"publisher","first-page":"2437","DOI":"10.1016\/0006-2952(74)90235-4","volume":"23","author":"M Schlumpf","year":"1974","unstructured":"Schlumpf, M., Lichtensteiger, W., Langemann, H., Waser, P. G., & Hefti, F. (1974). A fluorometric micromethod for the simultaneous determination of serotonin, noradrenaline and dopamine in milligram amounts of brain tissue. Biochemical Pharmacology, 23(17), 2437\u20132446.","journal-title":"Biochemical Pharmacology"},{"issue":"1","key":"8799_CR37","first-page":"25","volume":"51","author":"JC Shih","year":"1999","unstructured":"Shih, J. C., Chen, K., & Ridd, M. J. (1999). Role of MAO A and B in neurotransmitter metabolism and behavior. Polish Journal of Pharmacology, 51(1), 25\u201329.","journal-title":"Polish Journal of Pharmacology"},{"issue":"1","key":"8799_CR38","doi-asserted-by":"publisher","first-page":"2452","DOI":"10.1038\/s41598-023-29287-4","volume":"13","author":"R Singh","year":"2023","unstructured":"Singh, R., Zahra, W., Singh, S. S., Birla, H., Rathore, A. S., Keshri, P. K., Dilnashin, H., Singh, S., & Singh, S. P. (2023). Oleuropein confers neuroprotection against rotenone-induced model of Parkinson\u2019s disease via BDNF\/CREB\/Akt pathway. Scientific Reports, 13(1), 2452.","journal-title":"Scientific Reports"},{"key":"8799_CR39","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1007\/BF02756730","volume":"69","author":"EA Tsavkelova","year":"2000","unstructured":"Tsavkelova, E. A., Botvinko, V., & Oleskin, A. V. (2000). Colonial organization and intercellular communication in microorganisms. Microbiology, 69, 249\u2013265.","journal-title":"Microbiology"},{"issue":"1","key":"8799_CR40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12906-019-2780-5","volume":"20","author":"T Wang","year":"2020","unstructured":"Wang, T., Li, C., Han, B., Wang, Z., Meng, X., Zhang, L., He, J., & Fu, F. (2020). Neuroprotective effects of Danshensu on rotenone-induced Parkinson\u2019s disease models in vitro and in vivo. BMC Complementary Medicine and Therapies, 20(1), 1\u201310.","journal-title":"BMC Complementary Medicine and Therapies"},{"key":"8799_CR41","first-page":"1720621","volume":"2016","author":"L Xu","year":"2016","unstructured":"Xu, L., & Pu, J. (2016). Alpha-synuclein in Parkinson\u2019s disease: From pathogenetic dysfunction to potential clinical application. Parkinson\u2019s Disease, 2016, 1720621.","journal-title":"Parkinson\u2019s Disease"},{"key":"8799_CR42","doi-asserted-by":"crossref","unstructured":"Yadav, U. C. S. (2015). Oxidative stress-induced lipid peroxidation: Role in inflammation. In Free radicals in human health and disease (pp. 119\u2013129). Springer.","DOI":"10.1007\/978-81-322-2035-0_9"},{"issue":"8","key":"8799_CR43","doi-asserted-by":"publisher","DOI":"10.1016\/j.arabjc.2023.104982","volume":"16","author":"SAA Zaidi","year":"2023","unstructured":"Zaidi, S. A. A., Khan, M. A., Khan, M. R., Ahmed, H., Shahryar, Z. A., Sahibzada, M. U. K., Alghamdi, S., Aljuaid, A., Almehmadi, M., & Allahyani, M. (2023). Benzoic-D5 acid as D2 receptor agonist in the treatment of rotenone induced Parkinson\u2019s disease in mice. Arabian Journal of Chemistry, 16(8), 104982.","journal-title":"Arabian Journal of Chemistry"}],"container-title":["NeuroMolecular Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12017-024-08799-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12017-024-08799-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12017-024-08799-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T15:51:18Z","timestamp":1735660278000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12017-024-08799-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,1]]},"references-count":42,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["8799"],"URL":"https:\/\/doi.org\/10.1007\/s12017-024-08799-w","relation":{},"ISSN":["1559-1174"],"issn-type":[{"type":"electronic","value":"1559-1174"}],"subject":[],"published":{"date-parts":[[2024,8,1]]},"assertion":[{"value":"16 May 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 July 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 August 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Authors declared no financial or non-financial interests that are directly or indirectly related to the work submitted for publication.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Male Swiss Albino mice weighing around 28\u2009\u00b1\u20092\u00a0g were procured from the Animal House approved by the Ethical Committee CPCSEA Registration Number IAEC\/2022\/I\/5.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}],"article-number":"32"}}