{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T22:41:08Z","timestamp":1793400068432,"version":"4.5.0"},"reference-count":102,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T00:00:00Z","timestamp":1772841600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T00:00:00Z","timestamp":1772841600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neuromol Med"],"DOI":"10.1007\/s12017-026-08917-w","type":"journal-article","created":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T00:27:10Z","timestamp":1772843230000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Miro1 in Parkinson\u2019s Disease: A Key Regulator of Mitochondrial Homeostasis and Neurodegeneration"],"prefix":"10.1007","volume":"28","author":[{"given":"Gaurav","family":"Singh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simranpreet","family":"Kaur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2450-2975","authenticated-orcid":false,"given":"Khadga Raj","family":"Aran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,7]]},"reference":[{"key":"8917_CR20","doi-asserted-by":"publisher","unstructured":"Ariga, H., Takahashi-Niki, K., Kato, I., Maita, H., Niki, T., & Iguchi-Ariga, S. M. M. (2013). Neuroprotective function of DJ-1 in Parkinson\u2019s disease. Oxidative Medicine and Cellular Longevity, 2013, Article 683920. https:\/\/doi.org\/10.1155\/2013\/683920","DOI":"10.1155\/2013\/683920"},{"key":"8917_CR21","doi-asserted-by":"publisher","first-page":"251525642311810","DOI":"10.1177\/25152564231181020","volume":"6","author":"P Atakpa-Adaji","year":"2023","unstructured":"Atakpa-Adaji, P., & Ivanova, A. (2023). IP3R at ER-mitochondrial contact sites: Beyond the IP3R-GRP75-VDAC1 Ca\u00b2\u207a funnel. Contact (Thousand Oaks), 6, 25152564231181020. https:\/\/doi.org\/10.1177\/25152564231181020","journal-title":"Contact (Thousand Oaks)"},{"issue":"12","key":"8917_CR17","doi-asserted-by":"publisher","first-page":"105441","DOI":"10.1016\/j.jbc.2023.105441","volume":"299","author":"EE Baltrusaitis","year":"2023","unstructured":"Baltrusaitis, E. E., Ravitch, E. E., Fenton, A. R., Perez, T. A., Holzbaur, E. L., & Dominguez, R. (2023). Interaction between the mitochondrial adaptor MIRO and the motor adaptor TRAK. Journal of Biological Chemistry, 299(12), 105441. https:\/\/doi.org\/10.1016\/j.jbc.2023.105441","journal-title":"Journal of Biological Chemistry"},{"key":"8917_CR22","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.neuroscience.2025.09.025","volume":"587","author":"W Bao","year":"2025","unstructured":"Bao, W., Ge, Y., Huang, J., Li, Y., Luo, Y., & Huang, N. (2025). DJ-1\/PARK7 in Parkinson\u2019s disease: Mechanisms of pathogenesis and therapeutic potential. Neuroscience, 587, 1\u201313. https:\/\/doi.org\/10.1016\/j.neuroscience.2025.09.025","journal-title":"Neuroscience"},{"issue":"23","key":"8917_CR23","doi-asserted-by":"publisher","first-page":"4589","DOI":"10.1007\/s00018-019-03203-4","volume":"76","author":"AN Bayne","year":"2019","unstructured":"Bayne, A. N., & Trempe, J. F. (2019). Mechanisms of PINK1, ubiquitin and Parkin interactions in mitochondrial quality control and beyond. Cellular and Molecular Life Sciences, 76(23), 4589\u20134611. https:\/\/doi.org\/10.1007\/s00018-019-03203-4","journal-title":"Cellular and Molecular Life Sciences"},{"key":"8917_CR5","doi-asserted-by":"publisher","DOI":"10.1113\/JP284759","author":"BP Bean","year":"2024","unstructured":"Bean, B. P. (2024). Mechanisms of pacemaking in mammalian neurons. The Journal of physiology. https:\/\/doi.org\/10.1113\/JP284759","journal-title":"The Journal of physiology"},{"key":"8917_CR24","doi-asserted-by":"publisher","first-page":"789959","DOI":"10.3389\/fcell.2021.789959","volume":"9","author":"S Benhammouda","year":"2021","unstructured":"Benhammouda, S., Vishwakarma, A., Gatti, P., & Germain, M. (2021). Mitochondria endoplasmic reticulum contact sites (MERCs): Proximity ligation assay as a tool to study organelle interaction. Frontiers in Cell and Developmental Biology, 9, 789959. https:\/\/doi.org\/10.3389\/fcell.2021.789959","journal-title":"Frontiers in Cell and Developmental Biology"},{"issue":"8","key":"8917_CR25","doi-asserted-by":"publisher","first-page":"1353","DOI":"10.1093\/hmg\/ddaa066","volume":"29","author":"C Berenguer-Escuder","year":"2020","unstructured":"Berenguer-Escuder, C., Grossmann, D., Antony, P., Arena, G., Wasner, K., Massart, F., Jarazo, J., Walter, J., Schwamborn, J. C., Gr\u00fcnewald, A., & Kr\u00fcger, R. (2020). Impaired mitochondrial\u2013endoplasmic reticulum interaction and mitophagy in Miro1-mutant neurons in Parkinson\u2019s disease. Human Molecular Genetics, 29(8), 1353\u20131364. https:\/\/doi.org\/10.1093\/hmg\/ddaa066","journal-title":"Human Molecular Genetics"},{"issue":"9","key":"8917_CR26","doi-asserted-by":"publisher","first-page":"1502","DOI":"10.1002\/mds.28194","volume":"35","author":"V Bharat","year":"2020","unstructured":"Bharat, V., & Wang, X. (2020). Precision neurology for Parkinson\u2019s disease: Coupling Miro1-based diagnosis with drug discovery. Movement Disorders, 35(9), 1502\u20131508. https:\/\/doi.org\/10.1002\/mds.28194","journal-title":"Movement Disorders"},{"key":"8917_CR27","doi-asserted-by":"publisher","unstructured":"Bharat, V., Durairaj, A. S., Vanhauwaert, R., Li, L., Muir, C. M., Chandra, S., Kwak, C. S., Guen, L., Nandakishore, Y., Hsieh, P., Rensi, C. H., Altman, S. E., Greicius, R. B., Feng, M. D., L., & Wang, X. (2023). A mitochondrial inside-out iron-calcium signal reveals drug targets for Parkinson\u2019s disease. Cell Reports, 42(12). https:\/\/doi.org\/10.1016\/j.celrep.2023.113544. Article 113544.","DOI":"10.1016\/j.celrep.2023.113544"},{"issue":"21","key":"8917_CR28","doi-asserted-by":"publisher","first-page":"14569","DOI":"10.1074\/jbc.M114.563031","volume":"289","author":"N Birsa","year":"2014","unstructured":"Birsa, N., Norkett, R., Wauer, T., Mevissen, T. E. T., Wu, H. C., Foltynie, T., Bhatia, K., Hirst, W. D., Komander, D., Plun-Favreau, H., & Kittler, J. T. (2014). Lysine 27 ubiquitination of the mitochondrial transport protein Miro is dependent on serine 65 of the Parkin ubiquitin ligase. Journal of Biological Chemistry, 289(21), 14569\u201314582. https:\/\/doi.org\/10.1074\/jbc.M114.563031","journal-title":"Journal of Biological Chemistry"},{"key":"8917_CR30","doi-asserted-by":"publisher","unstructured":"Borbolis, F., Ploumi, C., & Palikaras, K. (2025). Calcium-mediated regulation of mitophagy: Implications in neurodegenerative diseases. npj Metabolism and Health Disease, 3(1). https:\/\/doi.org\/10.1038\/s44324-025-00049-2. Article 4.","DOI":"10.1038\/s44324-025-00049-2"},{"issue":"4","key":"8917_CR31","doi-asserted-by":"publisher","first-page":"699","DOI":"10.3233\/JPD-150642","volume":"5","author":"J Burr\u00e9","year":"2015","unstructured":"Burr\u00e9, J. (2015). The synaptic function of \u03b1-synuclein. Journal of Parkinson\u2019s Disease, 5(4), 699\u2013713. https:\/\/doi.org\/10.3233\/JPD-150642","journal-title":"Journal of Parkinson\u2019s Disease"},{"issue":"3","key":"8917_CR32","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1038\/s41419-023-05672-9","volume":"14","author":"P Calabresi","year":"2023","unstructured":"Calabresi, P., Mechelli, A., Natale, G., Volpicelli-Daley, L., Di Lazzaro, G., Ghiglieri, V., & Mercuri, N. B. (2023). Alpha-synuclein in Parkinson\u2019s disease and other synucleinopathies: From overt neurodegeneration back to early synaptic dysfunction. Cell Death & Disease, 14(3), 176. https:\/\/doi.org\/10.1038\/s41419-023-05672-9","journal-title":"Cell Death & Disease"},{"key":"8917_CR33","doi-asserted-by":"publisher","first-page":"1376","DOI":"10.1038\/s41467-023-36945-8","volume":"14","author":"JT Canty","year":"2023","unstructured":"Canty, J. T., Hensley, A., Aslan, M., Jack, A., & Yildiz, A. (2023). TRAK adaptors regulate the recruitment and activation of dynein and kinesin in mitochondrial transport. Nature Communications, 14, 1376. https:\/\/doi.org\/10.1038\/s41467-023-36945-8","journal-title":"Nature Communications"},{"issue":"10","key":"8917_CR15","doi-asserted-by":"publisher","first-page":"3607","DOI":"10.1093\/brain\/awaf051","volume":"148","author":"A Chemla","year":"2025","unstructured":"Chemla, A., Arena, G., Sacripanti, G., Barmpa, K., Zagare, A., Garcia, P., & Saraiva, C. (2025a). Parkinson\u2019s disease mutant Miro1 causes mitochondrial dysfunction and dopaminergic neuron loss. Brain, 148(10), 3607\u20133622. https:\/\/doi.org\/10.1093\/brain\/awaf051","journal-title":"Brain"},{"issue":"10","key":"8917_CR34","doi-asserted-by":"publisher","first-page":"3607","DOI":"10.1093\/brain\/awaf051","volume":"148","author":"A Chemla","year":"2025","unstructured":"Chemla, A., Arena, G., Sacripanti, G., Barmpa, K., Zagare, A., Garcia, P., Gorgogietas, V., Antony, P., Ohnmacht, J., Baron, A., Jung, J., Lind-Holm Mogensen, F., Michelucci, A., Marzesco, A. M., Buttini, M., Schmidt, T., Gr\u00fcnewald, A., Schwamborn, J. C., Kr\u00fcger, R., & Saraiva, C. (2025b). Parkinson\u2019s disease mutant Miro1 causes mitochondrial dysfunction and dopaminergic neuron loss. Brain, 148(10), 3607\u20133622. https:\/\/doi.org\/10.1093\/brain\/awaf051","journal-title":"Brain"},{"issue":"12","key":"8917_CR35","doi-asserted-by":"publisher","first-page":"1899","DOI":"10.1016\/j.neuron.2022.03.015","volume":"110","author":"XT Cheng","year":"2022","unstructured":"Cheng, X. T., Huang, N., & Sheng, Z. H. (2022). Programming axonal mitochondrial maintenance and bioenergetics in neurodegeneration and regeneration. Neuron, 110(12), 1899\u20131923. https:\/\/doi.org\/10.1016\/j.neuron.2022.03.015","journal-title":"Neuron"},{"key":"8917_CR36","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1186\/s12964-025-02172-5","volume":"23","author":"GE Choi","year":"2025","unstructured":"Choi, G. E., Park, J. Y., Park, M. R., Chae, C. W., Jung, Y. H., Lim, J. R., Yoon, J. H., Cho, J. H., & Han, H. J. (2025). Restoration of Miro1\u2019s N-terminal GTPase function alleviates prenatal stress-induced mitochondrial fission via Drp1 modulation. Cell Communication and Signaling, 23, 166. https:\/\/doi.org\/10.1186\/s12964-025-02172-5","journal-title":"Cell Communication and Signaling"},{"issue":"9","key":"8917_CR37","doi-asserted-by":"publisher","first-page":"2488","DOI":"10.3390\/biomedicines11092488","volume":"11","author":"VJ Clemente-Su\u00e1rez","year":"2023","unstructured":"Clemente-Su\u00e1rez, V. J., Redondo-Fl\u00f3rez, L., Beltr\u00e1n-Velasco, A. I., Ruisoto-Palomera, P., Tornero-Aguilera, J. F., & Ramos-Campo, D. J. (2023). Mitochondria and brain disease: A comprehensive review of pathological mechanisms and therapeutic opportunities. Biomedicines, 11(9), 2488. https:\/\/doi.org\/10.3390\/biomedicines11092488","journal-title":"Biomedicines"},{"issue":"3","key":"8917_CR38","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1007\/s10863-019-09798-4","volume":"51","author":"LP Dolgacheva","year":"2019","unstructured":"Dolgacheva, L. P., Berezhnov, A. V., Fedotova, E. I., Zinchenko, V. P., & Abramov, A. Y. (2019). Role of DJ-1 in the mechanism of pathogenesis of Parkinson\u2019s disease. Journal of Bioenergetics and Biomembranes, 51(3), 175\u2013188. https:\/\/doi.org\/10.1007\/s10863-019-09798-4","journal-title":"Journal of Bioenergetics and Biomembranes"},{"issue":"12","key":"8917_CR39","doi-asserted-by":"publisher","first-page":"1848","DOI":"10.1002\/jcb.30138","volume":"122","author":"FF Fatiga","year":"2021","unstructured":"Fatiga, F. F., Wang, L. J., Hsu, T., Capuno, J. I., & Fu, C. Y. (2021). Miro1 functions as an inhibitory regulator of MFN at elevated mitochondrial Ca\u00b2\u207a levels. Journal of Cellular Biochemistry, 122(12), 1848\u20131862. https:\/\/doi.org\/10.1002\/jcb.30138","journal-title":"Journal of Cellular Biochemistry"},{"key":"8917_CR40","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1016\/j.freeradbiomed.2015.09.002","volume":"89","author":"J Gao","year":"2015","unstructured":"Gao, J., Sang, M., Zhang, X., Zheng, T., Pan, J., Dai, M., Zhou, L., & Yang, S. (2015). Miro1-mediated mitochondrial dysfunction under high nutrient stress is linked to NOD-like receptor 3 (NLRP3)-dependent inflammatory responses in rat pancreatic beta cells. Free Radical Biology & Medicine, 89, 322\u2013332. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2015.09.002","journal-title":"Free Radical Biology & Medicine"},{"key":"8917_CR41","doi-asserted-by":"publisher","unstructured":"Gao, V., Briano, J. A., Komer, L. E., & Burr\u00e9, J. (2023). Functional and pathological effects of \u03b1-synuclein on synaptic SNARE complexes. Journal of Molecular Biology, 435(1). https:\/\/doi.org\/10.1016\/j.jmb.2022.167714","DOI":"10.1016\/j.jmb.2022.167714"},{"issue":"1","key":"8917_CR42","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/s13024-020-00367-7","volume":"15","author":"P Ge","year":"2020","unstructured":"Ge, P., Dawson, V. L., & Dawson, T. M. (2020). PINK1 and Parkin mitochondrial quality control: A source of regional vulnerability in Parkinson\u2019s disease. Molecular Neurodegeneration, 15(1), 20. https:\/\/doi.org\/10.1186\/s13024-020-00367-7","journal-title":"Molecular Neurodegeneration"},{"issue":"4","key":"8917_CR43","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1124\/pr.114.010397","volume":"67","author":"CL German","year":"2015","unstructured":"German, C. L., Baladi, M. G., McFadden, L. M., Hanson, G. R., & Fleckenstein, A. E. (2015). Regulation of the dopamine and vesicular monoamine transporters: Pharmacological targets and implications for disease. Pharmacological Reviews, 67(4), 1005\u20131024. https:\/\/doi.org\/10.1124\/pr.114.010397","journal-title":"Pharmacological Reviews"},{"key":"8917_CR44","doi-asserted-by":"publisher","first-page":"587","DOI":"10.3389\/fneur.2020.00587","volume":"11","author":"D Grossmann","year":"2020","unstructured":"Grossmann, D., Berenguer-Escuder, C., Chemla, A., Arena, G., & Kr\u00fcger, R. (2020). The emerging role of RHOT1\/Miro1 in the pathogenesis of Parkinson\u2019s disease. Frontiers in Neurology, 11, 587. https:\/\/doi.org\/10.3389\/fneur.2020.00587","journal-title":"Frontiers in Neurology"},{"issue":"8","key":"8917_CR45","doi-asserted-by":"publisher","first-page":"4281","DOI":"10.1073\/pnas.1909814117","volume":"117","author":"SJ Ham","year":"2020","unstructured":"Ham, S. J., Lee, D., Yoo, H., & Chung, J. (2020). Decision between mitophagy and apoptosis by Parkin via VDAC1 ubiquitination. Proceedings of the National Academy of Sciences of the United States of America, 117(8), 4281\u20134291. https:\/\/doi.org\/10.1073\/pnas.1909814117","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"12","key":"8917_CR19","doi-asserted-by":"publisher","first-page":"3436","DOI":"10.3390\/cells10123436","volume":"10","author":"LM Heger","year":"2021","unstructured":"Heger, L. M., Wise, R. M., Hees, J. T., Harbauer, A. B., & Burbulla, L. F. (2021). Mitochondrial phenotypes in Parkinson\u2019s diseases\u2014a focus on human iPSC-derived dopaminergic neurons. Cells, 10(12), 3436. https:\/\/doi.org\/10.3390\/cells10123436","journal-title":"Cells"},{"issue":"6","key":"8917_CR47","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1016\/j.stem.2016.08.002","volume":"19","author":"CH Hsieh","year":"2016","unstructured":"Hsieh, C. H., Shaltouki, A., Gonzalez, A. E., da Cruz, A. B., Burbulla, L. F., Lawrence, E. S., & Wang, X. (2016). Functional impairment in Miro degradation and mitophagy is a shared feature in familial and sporadic Parkinson\u2019s disease. Cell Stem Cell, 19(6), 709\u2013724. https:\/\/doi.org\/10.1016\/j.stem.2016.08.002","journal-title":"Cell Stem Cell"},{"issue":"6","key":"8917_CR46","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.1016\/j.cmet.2019.08.023","volume":"30","author":"CH Hsieh","year":"2019","unstructured":"Hsieh, C. H., Li, L., Vanhauwaert, R., Nguyen, K. T., Davis, M. D., Bu, G., Wszolek, Z. K., & Wang, X. (2019). Miro1 marks Parkinson\u2019s disease subset and Miro1 reducer rescues neuron loss in Parkinson\u2019s models. Cell Metabolism, 30(6), 1131\u20131140. https:\/\/doi.org\/10.1016\/j.cmet.2019.08.023","journal-title":"Cell Metabolism"},{"issue":"1","key":"8917_CR7","doi-asserted-by":"publisher","first-page":"73","DOI":"10.3390\/antiox15010073","volume":"15","author":"Y Hu","year":"2026","unstructured":"Hu, Y., Yang, Z., Wang, X., Li, X., & Wei, M. (2026). Oxidative Stress and Lysosomal Dysfunction in Neurodegenerative Diseases: Underlying Mechanisms and Nanotherapeutic Targeting Strategies. Antioxidants, 15(1), 73. https:\/\/doi.org\/10.3390\/antiox15010073","journal-title":"Antioxidants"},{"key":"8917_CR48","doi-asserted-by":"publisher","unstructured":"Huang, S., Lu, Y., Fang, W., Huang, Y., Li, Q., & Xu, Z. (2025). Neurodegenerative diseases and neuroinflammation-induced apoptosis. Open Life Sciences, 20(1). https:\/\/doi.org\/10.1515\/biol-2022-1051","DOI":"10.1515\/biol-2022-1051"},{"key":"8917_CR9","doi-asserted-by":"publisher","first-page":"1538166","DOI":"10.3389\/fnagi.2025.1538166","volume":"17","author":"J Jiao","year":"2025","unstructured":"Jiao, J., Liu, W., Gao, G., & Yang, H. (2025). Serine-129 phosphorylated \u03b1-synuclein drives mitochondrial dysfunction and calcium dysregulation in Parkinson\u2019s disease model. Frontiers in Aging Neuroscience, 17, 1538166. https:\/\/doi.org\/10.3389\/fnagi.2025.1538166","journal-title":"Frontiers in Aging Neuroscience"},{"issue":"2","key":"8917_CR16","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1007\/s11011-025-01552-7","volume":"40","author":"M Kaur","year":"2025","unstructured":"Kaur, M., & Aran, K. R. (2025). Unraveling the role of Nrf2 in dopaminergic neurons: a review of oxidative stress and mitochondrial dysfunction in Parkinson\u2019s disease. Metabolic Brain Disease, 40(2), 123. https:\/\/doi.org\/10.1007\/s11011-025-01552-7","journal-title":"Metabolic Brain Disease"},{"issue":"5","key":"8917_CR49","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1038\/ni.1863","volume":"11","author":"T Kawai","year":"2010","unstructured":"Kawai, T., & Akira, S. (2010). The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors. Nature Immunology, 11(5), 373\u2013384. https:\/\/doi.org\/10.1038\/ni.1863","journal-title":"Nature Immunology"},{"issue":"9","key":"8917_CR50","doi-asserted-by":"publisher","first-page":"7352","DOI":"10.1007\/s12035-018-0927-x","volume":"55","author":"L Kay","year":"2018","unstructured":"Kay, L., Pienaar, I. S., Cooray, R., et al. (2018). Understanding Miro GTPases: Implications in the treatment of neurodegenerative disorders. Molecular Neurobiology, 55(9), 7352\u20137365. https:\/\/doi.org\/10.1007\/s12035-018-0927-x","journal-title":"Molecular Neurobiology"},{"key":"8917_CR51","doi-asserted-by":"publisher","unstructured":"Kittler, J. T. (2015). Regulation of mitochondrial trafficking, function and quality control by the mitochondrial GTPases Miro1 and Miro2. SpringerPlus, 4(Suppl 1), L33. https:\/\/doi.org\/10.1186\/2193-1801-4-S1-L33","DOI":"10.1186\/2193-1801-4-S1-L33"},{"issue":"2","key":"8917_CR52","doi-asserted-by":"publisher","first-page":"28a","DOI":"10.1016\/j.bpj.2013.11.207","volume":"106","author":"J Klosowiak","year":"2014","unstructured":"Klosowiak, J., Focia, P., Chakravarthy, S., Landahl, E., Freymann, D., & Rice, S. (2014). Structural coupling of the EF hand and C-terminal GTPase domains in the mitochondrial protein Miro. Biophysical Journal, 106(2), 28a.","journal-title":"Biophysical Journal"},{"issue":"1","key":"8917_CR53","doi-asserted-by":"publisher","first-page":"205","DOI":"10.14670\/HH-20.205","volume":"20","author":"M Le Bras","year":"2005","unstructured":"Le Bras, M., Cl\u00e9ment, M. V., Pervaiz, S., & Brenner, C. (2005). Reactive oxygen species and the mitochondrial signaling pathway of cell death. Histology and Histopathology, 20(1), 205\u2013219. https:\/\/doi.org\/10.14670\/HH-20.205","journal-title":"Histology and Histopathology"},{"key":"8917_CR54","doi-asserted-by":"publisher","first-page":"237","DOI":"10.3389\/fnmol.2019.00237","volume":"12","author":"E Leandrou","year":"2019","unstructured":"Leandrou, E., Emmanouilidou, E., & Vekrellis, K. (2019). Voltage-gated calcium channels and \u03b1-synuclein: Implications in Parkinson\u2019s disease. Frontiers in Molecular Neuroscience, 12, 237. https:\/\/doi.org\/10.3389\/fnmol.2019.00237","journal-title":"Frontiers in Molecular Neuroscience"},{"issue":"4","key":"8917_CR56","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1007\/s10571-020-00887-2","volume":"41","author":"B Li","year":"2021","unstructured":"Li, B., Zhang, Y., Li, H., Gao, Y., Wang, W., & Chen, J. (2021). Miro1 regulates neuronal mitochondrial transport and distribution to alleviate neuronal damage in secondary brain injury after intracerebral hemorrhage in rats. Cellular and Molecular Neurobiology, 41(4), 795\u2013812. https:\/\/doi.org\/10.1007\/s10571-020-00887-2","journal-title":"Cellular and Molecular Neurobiology"},{"key":"8917_CR55","doi-asserted-by":"publisher","unstructured":"Li, A., Gao, M., Liu, B., et al. (2022). Mitochondrial autophagy: Molecular mechanisms and implications for cardiovascular disease. Cell Death & Disease, 13(5). https:\/\/doi.org\/10.1038\/s41419-022-04906-6","DOI":"10.1038\/s41419-022-04906-6"},{"issue":"5","key":"8917_CR57","doi-asserted-by":"publisher","first-page":"1864","DOI":"10.4103\/NRR.NRR-D-24-01539","volume":"21","author":"K Li","year":"2026","unstructured":"Li, K., Chen, R., Wang, R., Fan, W., Zhao, N., Yang, Z., & Yan, J. (2026). Neuroinflammation in neurodegenerative diseases: Focusing on the mediation of T lymphocytes. Neural Regeneration Research, 21(5), 1864\u20131889. https:\/\/doi.org\/10.4103\/NRR.NRR-D-24-01539","journal-title":"Neural Regeneration Research"},{"issue":"10","key":"8917_CR59","doi-asserted-by":"publisher","first-page":"1972","DOI":"10.1016\/j.biocel.2009.05.013","volume":"41","author":"X Liu","year":"2009","unstructured":"Liu, X., & Hajn\u00f3czky, G. (2009). Ca\u00b2\u207a-dependent regulation of mitochondrial dynamics by the Miro-Milton complex. The International Journal of Biochemistry & Cell Biology, 41(10), 1972\u20131976. https:\/\/doi.org\/10.1016\/j.biocel.2009.05.013","journal-title":"The International Journal of Biochemistry & Cell Biology"},{"key":"8917_CR58","doi-asserted-by":"publisher","unstructured":"Liu, T., Zhang, L., Joo, D., & Sun, S. C. (2017). NF-\u03baB signaling in inflammation. Signal Transduction and Targeted Therapy, 2., Article 17023. https:\/\/doi.org\/10.1038\/sigtrans.2017.23","DOI":"10.1038\/sigtrans.2017.23"},{"issue":"1","key":"8917_CR10","doi-asserted-by":"publisher","first-page":"149","DOI":"10.3390\/biom15010149","volume":"15","author":"M Liu","year":"2025","unstructured":"Liu, M., Liu, S., Lin, Z., Chen, X., Jiao, Q., Du, X., & Jiang, H. (2025). Targeting the interplay between autophagy and the Nrf2 pathway in Parkinson\u2019s disease with potential therapeutic implications. Biomolecules, 15(1), 149. https:\/\/doi.org\/10.3390\/biom15010149","journal-title":"Biomolecules"},{"key":"8917_CR60","doi-asserted-by":"publisher","first-page":"102747","DOI":"10.1016\/j.conb.2023.102747","volume":"81","author":"G L\u00f3pez-Dom\u00e9nech","year":"2023","unstructured":"L\u00f3pez-Dom\u00e9nech, G., & Kittler, J. T. (2023). Mitochondrial regulation of local supply of energy in neurons. Current Opinion in Neurobiology, 81, 102747. https:\/\/doi.org\/10.1016\/j.conb.2023.102747","journal-title":"Current Opinion in Neurobiology"},{"issue":"3","key":"8917_CR61","doi-asserted-by":"publisher","first-page":"321","DOI":"10.15252\/embj.201696380","volume":"37","author":"G L\u00f3pez-Dom\u00e9nech","year":"2018","unstructured":"L\u00f3pez-Dom\u00e9nech, G., Covill-Cooke, C., Ivankovic, D., Sheehan, D., Feldstein, N., Tolkovsky, A. M., & Kittler, J. T. (2018). Miro proteins coordinate microtubule- and actin-dependent mitochondrial transport and distribution. The EMBO Journal, 37(3), 321\u2013336. https:\/\/doi.org\/10.15252\/embj.201696380","journal-title":"The EMBO Journal"},{"issue":"2","key":"8917_CR62","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/j.celrep.2016.09.004","volume":"17","author":"G L\u00f3pez-Dom\u00e9nech","year":"2016","unstructured":"L\u00f3pez-Dom\u00e9nech, G., Higgs, N. F., Vaccaro, V., Ro\u0161, H., Arancibia-C\u00e1rcamo, I. L., MacAskill, A. F., & Kittler, J. T. (2016). Loss of dendritic complexity precedes neurodegeneration in a mouse model with disrupted mitochondrial distribution in mature dendrites. Cell Reports, 17(2), 317\u2013327. https:\/\/doi.org\/10.1016\/j.celrep.2016.09.004","journal-title":"Cell Reports"},{"issue":"14","key":"8917_CR2","doi-asserted-by":"publisher","first-page":"EMBJ2018100715","DOI":"10.15252\/embj.2018100715","volume":"40","author":"G L\u00f3pez-Dom\u00e9nech","year":"2021","unstructured":"L\u00f3pez-Dom\u00e9nech, G., Howden, J. H., Covill\u2010Cooke, C., Morfill, C., Patel, J. V., B\u00fcrli, R., & Kittler, J. T. (2021a). Loss of neuronal Miro1 disrupts mitophagy and induces hyperactivation of the integrated stress response. The EMBO journal, 40(14), EMBJ2018100715. https:\/\/doi.org\/10.15252\/embj.2018100715","journal-title":"The EMBO journal"},{"key":"8917_CR63","doi-asserted-by":"publisher","unstructured":"L\u00f3pez-Dom\u00e9nech, G., Howden, J. H., Covill-Cooke, C., Annam, K., Sibilla, S., Tollis, S., Trost, M., Schwarz, N., Fawcett, P., & Kittler, J. T. (2021b). Loss of neuronal Miro1 disrupts mitophagy and induces hyperactivation of the integrated stress response. The EMBO Journal, 40(14). https:\/\/doi.org\/10.15252\/embj.2018100715. Article e100715.","DOI":"10.15252\/embj.2018100715"},{"key":"8917_CR65","doi-asserted-by":"publisher","first-page":"1268883","DOI":"10.3389\/fnins.2023.1268883","volume":"17","author":"D Lu","year":"2023","unstructured":"Lu, D., Feng, Y., Liu, G., Yang, Y., Ren, Y., Chen, Z., Sun, X., Guan, Y., & Wang, Z. (2023). Mitochondrial transport in neurons and evidence for its involvement in acute neurological disorders. Frontiers in Neuroscience, 17, 1268883. https:\/\/doi.org\/10.3389\/fnins.2023.1268883","journal-title":"Frontiers in Neuroscience"},{"key":"8917_CR64","doi-asserted-by":"publisher","unstructured":"Lu, D., Feng, Y., Liu, G. (2023). Mitochondrial transport in neurons and evidence for its involvement in acute neurological disorders. Frontiers in Neuroscience, 17, 1268883. https:\/\/doi.org\/10.3389\/fnins.2023.1268883","DOI":"10.3389\/fnins.2023.1268883"},{"key":"8917_CR66","doi-asserted-by":"publisher","first-page":"1498756","DOI":"10.3389\/fnagi.2024.1498756","volume":"16","author":"Y Luo","year":"2025","unstructured":"Luo, Y., Qiao, L., Li, M., Wen, X., Zhang, W., & Li, X. (2025). Global, regional, national epidemiology and trends of Parkinson\u2019s disease from 1990 to 2021: Findings from the Global Burden of Disease Study 2021. Frontiers in Aging Neuroscience, 16, 1498756. https:\/\/doi.org\/10.3389\/fnagi.2024.1498756","journal-title":"Frontiers in Aging Neuroscience"},{"issue":"1","key":"8917_CR67","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1159\/000533602","volume":"15","author":"Y Lyu","year":"2023","unstructured":"Lyu, Y., Wang, T., Huang, S., & Zhang, Z. (2023). Mitochondrial damage-associated molecular patterns and metabolism in the regulation of innate immunity. Journal of Innate Immunity, 15(1), 665\u2013679. https:\/\/doi.org\/10.1159\/000533602","journal-title":"Journal of Innate Immunity"},{"issue":"4","key":"8917_CR68","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1016\/j.neuron.2009.01.030","volume":"61","author":"AF MacAskill","year":"2009","unstructured":"MacAskill, A. F., Rinholm, J. E., Twelvetrees, A. E., Arancibia-Carcamo, I. L., Muir, J., Fransson, A., Aspenstr\u00f6m, P., Attwell, D., & Kittler, J. T. (2009). Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses. Neuron, 61(4), 541\u2013555. https:\/\/doi.org\/10.1016\/j.neuron.2009.01.030","journal-title":"Neuron"},{"key":"8917_CR69","doi-asserted-by":"publisher","unstructured":"Martinez-Vicente, M. (2017). Neuronal mitophagy in neurodegenerative diseases. Frontiers in Molecular Neuroscience, 10. https:\/\/doi.org\/10.3389\/fnmol.2017.00064. Article 64.","DOI":"10.3389\/fnmol.2017.00064"},{"key":"8917_CR70","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1038\/s41419-018-0340-7","volume":"9","author":"D Martinvalet","year":"2018","unstructured":"Martinvalet, D. (2018). The role of the mitochondria and the endoplasmic reticulum contact sites in the development of the immune responses. Cell Death And Disease, 9, 336. https:\/\/doi.org\/10.1038\/s41419-018-0340-7","journal-title":"Cell Death And Disease"},{"issue":"24","key":"8917_CR1","doi-asserted-by":"publisher","first-page":"11852","DOI":"10.3390\/ijms262411852","volume":"26","author":"E Marzetti","year":"2025","unstructured":"Marzetti, E., Di Lorenzo, R., Calvani, R., Coelho-J\u00fanior, H. J., Landi, F., Pesce, V., & Picca, A. (2025). Linking Cell Architecture to Mitochondrial Signaling in Neurodegeneration: The Role of Intermediate Filaments. International Journal of Molecular Sciences, 26(24), 11852. https:\/\/doi.org\/10.3390\/ijms262411852","journal-title":"International Journal of Molecular Sciences"},{"key":"8917_CR71","doi-asserted-by":"publisher","DOI":"10.1101\/2021.06.03.446977","author":"L Mitchell","year":"2021","unstructured":"Mitchell, L., Reda, K. E., Fatima, H., Vasquez, C. E., & Quintero-Carmona, O. A. (2021). The C-terminal regions of TRAK proteins contain MIRO-independent mitochondrial outer membrane binding domains. bioRxiv. https:\/\/doi.org\/10.1101\/2021.06.03.446977","journal-title":"bioRxiv"},{"issue":"1","key":"8917_CR72","doi-asserted-by":"publisher","first-page":"4399","DOI":"10.1038\/s41467-019-12382-4","volume":"10","author":"S Modi","year":"2019","unstructured":"Modi, S., L\u00f3pez-Dom\u00e9nech, G., Halff, E. F., Covill-Cooke, C., Ivankovic, D., Melandri, D., Arancibia-C\u00e1rcamo, I. L., Burden, J. J., Lowe, A. R., & Kittler, J. T. (2019). Miro clusters regulate ER\u2013mitochondria contact sites and link cristae organization to the mitochondrial transport machinery. Nature Communications, 10(1), 4399. https:\/\/doi.org\/10.1038\/s41467-019-12382-4","journal-title":"Nature Communications"},{"issue":"1","key":"8917_CR12","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1515\/revneuro-2024-0080","volume":"36","author":"AA Mohamed Yusoff","year":"2025","unstructured":"Mohamed Yusoff, A. A., & Mohd Khair, S. Z. N. (2025). Unraveling mitochondrial dysfunction: comprehensive perspectives on its impact on neurodegenerative diseases. Reviews in the Neurosciences, 36(1), 53\u201390. https:\/\/doi.org\/10.1515\/revneuro-2024-0080","journal-title":"Reviews in the Neurosciences"},{"issue":"4","key":"8917_CR13","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1080\/10409238.2021.1925216","volume":"56","author":"Z Nahacka","year":"2021","unstructured":"Nahacka, Z., Zobalova, R., Dubisova, M., Rohlena, J., & Neuzil, J. (2021). Miro proteins connect mitochondrial function and intercellular transport. Critical Reviews in Biochemistry and Molecular Biology, 56(4), 401\u2013425. https:\/\/doi.org\/10.1080\/10409238.2021.1925216","journal-title":"Critical Reviews in Biochemistry and Molecular Biology"},{"issue":"4","key":"8917_CR6","doi-asserted-by":"publisher","first-page":"544","DOI":"10.3390\/jmp5040037","volume":"5","author":"D Nam","year":"2024","unstructured":"Nam, D., Kim, H., Han, S. J., Son, I., & Ho, D. H. (2024). Effects of calcium ion dyshomeostasis and calcium ion-Induced excitotoxicity in Parkinson\u2019s disease. Journal of Molecular Pathology, 5(4), 544\u2013557. https:\/\/doi.org\/10.3390\/jmp5040037","journal-title":"Journal of Molecular Pathology"},{"issue":"s1","key":"8917_CR3","doi-asserted-by":"publisher","first-page":"S399","DOI":"10.3233\/JAD-220682","volume":"94","author":"P Naren","year":"2023","unstructured":"Naren, P., Cholkar, A., Kamble, S., Khan, S. S., Srivastava, S., Madan, J., & Khatri, D. K. (2023). Pathological and therapeutic advances in Parkinson\u2019s disease: mitochondria in the interplay. Journal of Alzheimer\u2019s Disease, 94(s1), S399\u2013S428. https:\/\/doi.org\/10.3233\/JAD-220682","journal-title":"Journal of Alzheimer\u2019s Disease"},{"issue":"4","key":"8917_CR73","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1016\/j.celrep.2018.03.098","volume":"23","author":"N Nemani","year":"2018","unstructured":"Nemani, N., Carvalho, E., Tomar, D., Dong, Z., Ketschek, A., Breves, S. L., Ja\u00f1a, F., Worth, A. M., Heffler, J., Palaniappan, P., Tripathi, A., Subbiah, R., Riitano, M. F., Seelam, A., Manfred, T., Itoh, K., Meng, S., Sesaki, H., Craigen, W. J., & Madesh, M. (2018). MIRO-1 determines mitochondrial shape transition upon GPCR activation and Ca\u00b2\u207a stress. Cell Reports, 23(4), 1005\u20131019. https:\/\/doi.org\/10.1016\/j.celrep.2018.03.098","journal-title":"Cell Reports"},{"issue":"35","key":"8917_CR74","doi-asserted-by":"publisher","first-page":"E3631","DOI":"10.1073\/pnas.1402449111","volume":"111","author":"TT Nguyen","year":"2014","unstructured":"Nguyen, T. T., Oh, S. S., Weaver, D., Lewandowska, A., Maxfield, D., Schuler, M. H., Smith, N. K., Macfarlane, J., Saunders, G., Palmer, C. A., Sreetama, S. C., Tong, B. C., Figueroa-Romero, C., Williams, S. L., Hollenbeck, P. J., Shea, T. B., Polster, B. M., & Schon, E. A. (2014). Loss of Miro1-directed mitochondrial movement results in a novel murine model for neuron disease. Proceedings of the National Academy of Sciences of the United States of America, 111(35), E3631\u2013E3640. https:\/\/doi.org\/10.1073\/pnas.1402449111","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"8917_CR75","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1196\/annals.1427.002","volume":"1147","author":"DG Nicholls","year":"2008","unstructured":"Nicholls, D. G. (2008). Oxidative stress and energy crises in neuronal dysfunction. Annals of the New York Academy of Sciences, 1147, 53\u201360. https:\/\/doi.org\/10.1196\/annals.1427.002","journal-title":"Annals of the New York Academy of Sciences"},{"key":"8917_CR76","doi-asserted-by":"publisher","first-page":"Article100030","DOI":"10.1016\/j.bbih.2019.100030","volume":"2","author":"RA Nolan","year":"2020","unstructured":"Nolan, R. A., Reeb, K. L., Rong, Y., Matt, S. M., Johnson, H. S., Runner, K., & Gaskill, P. J. (2020). Dopamine activates NF-\u03baB and primes the NLRP3 inflammasome in primary human macrophages. Brain Behavior & Immunity - Health, 2, Article100030. https:\/\/doi.org\/10.1016\/j.bbih.2019.100030","journal-title":"Brain Behavior & Immunity - Health"},{"issue":"12","key":"8917_CR77","doi-asserted-by":"publisher","first-page":"592","DOI":"10.5483\/BMBRep.2021.54.12.107","volume":"54","author":"GH Park","year":"2021","unstructured":"Park, G. H., Park, J. H., & Chung, K. C. (2021). Precise control of mitophagy through ubiquitin proteasome system and deubiquitin proteases and their dysfunction in Parkinson\u2019s disease. BMB Reports, 54(12), 592\u2013600. https:\/\/doi.org\/10.5483\/BMBRep.2021.54.12.107","journal-title":"BMB Reports"},{"key":"8917_CR78","doi-asserted-by":"publisher","unstructured":"Peggion, C., Cal\u00ec, T., & Brini, M. (2024). Mitochondria dysfunction and neuroinflammation in neurodegeneration: Who comes first? Antioxidants, 13(2). https:\/\/doi.org\/10.3390\/antiox13020240. Article 240.","DOI":"10.3390\/antiox13020240"},{"issue":"12","key":"8917_CR79","doi-asserted-by":"publisher","first-page":"3349","DOI":"10.4103\/1673-5374.384116","volume":"20","author":"Y Peng","year":"2025","unstructured":"Peng, Y., Zhou, L., Jin, Y., Wu, D., Chen, N., Zhang, C., Liu, H., Li, C., Ning, R., Yang, X., & Mao, Q. (2025). Calcium bridges built by mitochondria-associated endoplasmic reticulum membranes: Potential targets for neural repair in neurological diseases. Neural Regeneration Research, 20(12), 3349\u20133369. https:\/\/doi.org\/10.4103\/1673-5374.384116","journal-title":"Neural Regeneration Research"},{"issue":"7\u20139","key":"8917_CR18","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1089\/ars.2022.0122","volume":"38","author":"M Perrone","year":"2023","unstructured":"Perrone, M., Patergnani, S., Di Mambro, T., Palumbo, L., Wieckowski, M. R., Giorgi, C., & Pinton, P. (2023). Calcium homeostasis in the control of mitophagy. Antioxidants & redox signaling, 38(7\u20139), 581\u2013598. https:\/\/doi.org\/10.1089\/ars.2022.0122","journal-title":"Antioxidants & redox signaling"},{"key":"8917_CR80","doi-asserted-by":"publisher","first-page":"RP107983","DOI":"10.7554\/eLife.107983.1","volume":"14","author":"L Qian","year":"2025","unstructured":"Qian, L., Koval, O. M., Endoni, B. T., Juhr, D., Stein, C. S., Allamargot, C., Lin, L. H., Guo, D. F., Rahmouni, K., Boudreau, R. L., Streeter, J., Thiel, W. H., & Grumbach, I. M. (2025). MIRO1 controls energy production and proliferation of vascular smooth muscle cells. eLife, 14, RP107983. https:\/\/doi.org\/10.7554\/eLife.107983.1","journal-title":"eLife"},{"key":"8917_CR81","doi-asserted-by":"publisher","first-page":"24","DOI":"10.37349\/ent.2023.00036","volume":"3","author":"K Radad","year":"2023","unstructured":"Radad, K., Moldzio, R., Krewenka, C., Kranner, B., & Rausch, W. D. (2023). Pathophysiology of non-motor signs in Parkinson\u2019s disease: Some recent updating with brief presentation. Exploration of Neuroprotective Therapy, 3, 24\u201346. https:\/\/doi.org\/10.37349\/ent.2023.00036","journal-title":"Exploration of Neuroprotective Therapy"},{"issue":"1","key":"8917_CR82","doi-asserted-by":"publisher","first-page":"Article6173","DOI":"10.1038\/s41467-025-61174-6","volume":"16","author":"EE Ravitch","year":"2025","unstructured":"Ravitch, E. E., Baltrusaitis, E. E., Perez, T. A., Barrie, K. R., Fenton, A. R., Holzbaur, E. L. F., & Dominguez, R. (2025a). Structural-functional characterization of the MIRO1-TRAK1 complex. Nature Communications, 16(1), Article6173.","journal-title":"Nature Communications"},{"key":"8917_CR83","doi-asserted-by":"publisher","unstructured":"Ravitch, E. E., Baltrusaitis, E. E., Perez, T. A., Dominguez, K. M., Sainati, V., & Dominguez, K. [or next listed author, if different in your source]. (2025b). Structural-functional characterization of the MIRO1-TRAK1 complex. Nature Communications, 16, 6173. https:\/\/doi.org\/10.1038\/s41467-025-61174-6","DOI":"10.1038\/s41467-025-61174-6"},{"key":"8917_CR84","doi-asserted-by":"publisher","unstructured":"Ray, B., Mahalakshmi, A. M., Tuladhar, S., Bhat, A., & Srinivasan, A. (2021). & others. Janus-faced \u03b1-synuclein: Role in Parkinson\u2019s disease. Frontiers in Cell and Developmental Biology, 9, Article 673395. https:\/\/doi.org\/10.3389\/fcell.2021.673395","DOI":"10.3389\/fcell.2021.673395"},{"issue":"9","key":"8917_CR85","doi-asserted-by":"publisher","first-page":"1391","DOI":"10.1016\/j.febslet.2009.04.015","volume":"583","author":"K Reis","year":"2009","unstructured":"Reis, K., Fransson, \u00c5., & Aspenstr\u00f6m, P. (2009). The Miro GTPases: At the heart of the mitochondrial transport machinery. FEBS Letters, 583(9), 1391\u20131398. https:\/\/doi.org\/10.1016\/j.febslet.2009.04.015","journal-title":"FEBS Letters"},{"issue":"8","key":"8917_CR86","doi-asserted-by":"publisher","first-page":"e56297","DOI":"10.15252\/embr.202256297","volume":"24","author":"X Ren","year":"2023","unstructured":"Ren, X., Zhou, H., Sun, Y., Zhang, J., Liu, Q., & Wang, H. (2023). MIRO-1 interacts with VDAC-1 to regulate mitochondrial membrane potential in Caenorhabditis elegans. EMBO Reports, 24(8), e56297. https:\/\/doi.org\/10.15252\/embr.202256297","journal-title":"EMBO Reports"},{"issue":"10\u201312","key":"8917_CR87","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1089\/ars.2022.0106","volume":"38","author":"A Sarkar","year":"2023","unstructured":"Sarkar, A., Rasheed, M. S. U., & Singh, M. P. (2023). Redox modulation of mitochondrial proteins in the neurotoxicant models of Parkinson\u2019s disease. Antioxidants & Redox Signaling, 38(10\u201312), 824\u2013852. https:\/\/doi.org\/10.1089\/ars.2022.0106","journal-title":"Antioxidants & Redox Signaling"},{"key":"8917_CR4","doi-asserted-by":"publisher","first-page":"966209","DOI":"10.3389\/fnmol.2022.966209","volume":"15","author":"L Schwarz","year":"2022","unstructured":"Schwarz, L., Sharma, K., Dodi, L. D., Rieder, L. S., Fallier-Becker, P., Casadei, N., & Fitzgerald, J. C. (2022). Miro1 R272Q disrupts mitochondrial calcium handling and neurotransmitter uptake in dopaminergic neurons. Frontiers in Molecular Neuroscience, 15, 966209. https:\/\/doi.org\/10.3389\/fnmol.2022.966209","journal-title":"Frontiers in Molecular Neuroscience"},{"issue":"1","key":"8917_CR8","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1007\/s12035-021-02596-3","volume":"59","author":"IN Serratos","year":"2022","unstructured":"Serratos, I. N., Hernandez-Perez, E., Campos, C., Aschner, M., & Santamar\u00eda, A. (2022). An update on the critical role of \u03b1-synuclein in Parkinson\u2019s disease and other synucleinopathies: from tissue to cellular and molecular levels. Molecular neurobiology, 59(1), 620\u2013642. https:\/\/doi.org\/10.1007\/s12035-021-02596-3","journal-title":"Molecular neurobiology"},{"issue":"4","key":"8917_CR89","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1007\/s00401-018-1873-4","volume":"136","author":"A Shaltouki","year":"2018","unstructured":"Shaltouki, A., Hsieh, C. H., Kim, M. J., & Wang, X. (2018). Alpha-synuclein delays mitophagy and targeting Miro rescues neuron loss in Parkinson\u2019s models. Acta Neuropathologica, 136(4), 607\u2013620. https:\/\/doi.org\/10.1007\/s00401-018-1873-4","journal-title":"Acta Neuropathologica"},{"issue":"41","key":"8917_CR91","doi-asserted-by":"publisher","first-page":"E6097","DOI":"10.1073\/pnas.1612283113","volume":"113","author":"E Shlevkov","year":"2016","unstructured":"Shlevkov, E., Kramer, T., Schapansky, J., LaVoie, M. J., & Schwarz, T. L. (2016). Miro phosphorylation sites regulate Parkin recruitment and mitochondrial motility. Proceedings of the National Academy of Sciences of the United States of America, 113(41), E6097\u2013E6106. https:\/\/doi.org\/10.1073\/pnas.1612283113","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"8917_CR92","doi-asserted-by":"publisher","unstructured":"Smith, K. P., Focia, P. J., Chakravarthy, S., Landahl, E. C., Klosowiak, J. L., Rice, S. E., & Freymann, D. M. (2020). Insight into human Miro1\/2 domain organization based on the structure of its N-terminal GTPase. Journal of Structural Biology, 212(3). https:\/\/doi.org\/10.1016\/j.jsb.2020.107656","DOI":"10.1016\/j.jsb.2020.107656"},{"issue":"48","key":"8917_CR93","doi-asserted-by":"publisher","first-page":"15996","DOI":"10.1523\/JNEUROSCI.2068-15.2015","volume":"35","author":"TL Stephen","year":"2015","unstructured":"Stephen, T. L., Higgs, N. F., Sheehan, D. F., Awabdh, A., L\u00f3pez-Dom\u00e9nech, S., Arancibia-Carcamo, G., I. L., & Kittler, J. T. (2015). Miro1 regulates activity-driven positioning of mitochondria within astrocytic processes apposed to synapses to regulate intracellular calcium signaling. Journal of Neuroscience, 35(48), 15996\u201316011. https:\/\/doi.org\/10.1523\/JNEUROSCI.2068-15.2015","journal-title":"Journal of Neuroscience"},{"issue":"1","key":"8917_CR94","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/cells5010001","volume":"5","author":"BL Tang","year":"2016","unstructured":"Tang, B. L. (2016). MIRO GTPases in mitochondrial transport, homeostasis and pathology. Cells, 5(1), 1. https:\/\/doi.org\/10.3390\/cells5010001","journal-title":"Cells"},{"issue":"11","key":"8917_CR95","doi-asserted-by":"publisher","first-page":"5954","DOI":"10.3390\/ijms23115954","volume":"23","author":"RI Teleanu","year":"2022","unstructured":"Teleanu, R. I., Niculescu, A. G., Roza, E., Vlad\u00e2cenco, O., Grumezescu, A. M., & Teleanu, D. M. (2022). Neurotransmitters\u2014Key factors in neurological and neurodegenerative disorders of the central nervous system. International Journal of Molecular Sciences, 23(11), 5954. https:\/\/doi.org\/10.3390\/ijms23115954","journal-title":"International Journal of Molecular Sciences"},{"issue":"3","key":"8917_CR96","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1042\/EBC20170104","volume":"62","author":"L Tilokani","year":"2018","unstructured":"Tilokani, L., Nagashima, S., Paupe, V., & Prudent, J. (2018). Mitochondrial dynamics: Overview of molecular mechanisms. Essays in Biochemistry, 62(3), 341\u2013360. https:\/\/doi.org\/10.1042\/EBC20170104","journal-title":"Essays in Biochemistry"},{"issue":"4","key":"8917_CR97","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1016\/j.cell.2011.10.018","volume":"147","author":"X Wang","year":"2011","unstructured":"Wang, X., Winter, D., Ashrafi, G., Schlehe, J., Wong, Y. L., Selkoe, D., Rice, S., Steen, J., LaVoie, M. J., & Schwarz, T. L. (2011). PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility. Cell, 147(4), 893\u2013906.","journal-title":"Cell"},{"issue":"3","key":"8917_CR11","doi-asserted-by":"publisher","first-page":"559","DOI":"10.24272\/j.issn.2095-8137.2022.406","volume":"44","author":"Z Wang","year":"2023","unstructured":"Wang, Z., Chan, S. W., Zhao, H., Miu, K. K., & Chan, W. Y. (2023). Outlook of PINK1\/Parkin signaling in molecular etiology of Parkinson\u2019s disease, with insights into Pink1 knockout models. Zoological Research, 44(3), 559. https:\/\/doi.org\/10.24272\/j.issn.2095-8137.2022.406","journal-title":"Zoological Research"},{"issue":"8","key":"8917_CR98","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1242\/jcs.01118","volume":"117","author":"K Wennerberg","year":"2004","unstructured":"Wennerberg, K., & Der, C. J. (2004). Rho-family GTPases: It\u2019s not only Rac and Rho (and I like it). Journal of Cell Science, 117(8), 1301\u20131312. https:\/\/doi.org\/10.1242\/jcs.01118","journal-title":"Journal of Cell Science"},{"key":"8917_CR99","doi-asserted-by":"publisher","unstructured":"Xiao, B., Kuruvilla, J., & Tan, E. K. (2022). Mitophagy and reactive oxygen species interplay in Parkinson\u2019s disease. npj Parkinson\u2019s Disease, 8(1). https:\/\/doi.org\/10.1038\/s41531-022-00402-y. Article 135.","DOI":"10.1038\/s41531-022-00402-y"},{"issue":"1","key":"8917_CR100","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1186\/s12967-025-07605-w","volume":"24","author":"W Xu","year":"2025","unstructured":"Xu, W., Xu, X., Zhang, Y., Li, F., & Xia, D. (2025). Mitochondrial fission and fusion in inflammatory diseases: Mechanisms and therapeutic implications. Journal of Translational Medicine, 24(1), 127. https:\/\/doi.org\/10.1186\/s12967-025-07605-w","journal-title":"Journal of Translational Medicine"},{"key":"8917_CR101","doi-asserted-by":"publisher","unstructured":"Yu, H., Lin, L., Zhang, Z., Zhang, J., & Wu, H. (2020). Targeting NF-\u03baB pathway for the therapy of diseases: Mechanism and clinical study. Signal Transduction and Targeted Therapy, 5(1). https:\/\/doi.org\/10.1038\/s41392-020-00312-6","DOI":"10.1038\/s41392-020-00312-6"},{"key":"8917_CR102","doi-asserted-by":"publisher","unstructured":"Zagare, A., Sauter, T., Barmpa, K., Pacheco, M., Kr\u00fcger, R., Schwamborn, J. C., & Saraiva, C. (2025). MIRO1 mutation leads to metabolic maladaptation resulting in Parkinson\u2019s disease-associated dopaminergic neuron loss. npj Systems Biology and Applications, 11(1). https:\/\/doi.org\/10.1038\/s41540-025-00509-x","DOI":"10.1038\/s41540-025-00509-x"},{"key":"8917_CR103","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.neuroscience.2025.05.019","volume":"577","author":"L Zeng","year":"2025","unstructured":"Zeng, L., Yang, J., Zhang, C., Zhu, J., Zhong, S., Liu, X., Xie, H., Wang, L., Chen, L., Zhong, M., Hua, F., & Liang, W. (2025). Miro1: A potential target for treating neurological disorders. Neuroscience, 577, 228\u2013239. https:\/\/doi.org\/10.1016\/j.neuroscience.2025.05.019","journal-title":"Neuroscience"},{"issue":"6","key":"8917_CR104","doi-asserted-by":"publisher","first-page":"5785","DOI":"10.3390\/ijms24065785","volume":"24","author":"M Zerihun","year":"2023","unstructured":"Zerihun, M., Sukumaran, S., & Qvit, N. (2023). The Drp1-mediated mitochondrial fission protein interactome as an emerging core player in mitochondrial dynamics and cardiovascular disease therapy. International Journal of Molecular Sciences, 24(6), 5785. https:\/\/doi.org\/10.3390\/ijms24065785","journal-title":"International Journal of Molecular Sciences"},{"key":"8917_CR105","doi-asserted-by":"publisher","first-page":"e2501","DOI":"10.1038\/cddis.2016.396","volume":"7","author":"N Zhuang","year":"2016","unstructured":"Zhuang, N., Li, L., Chen, S., et al. (2016). PINK1-dependent phosphorylation of PINK1 and Parkin is essential for mitochondrial quality control. Cell Death & Disease, 7, e2501. https:\/\/doi.org\/10.1038\/cddis.2016.396","journal-title":"Cell Death & Disease"},{"issue":"5\u20136","key":"8917_CR14","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1080\/21541248.2020.1843957","volume":"12","author":"KE Zinsmaier","year":"2021","unstructured":"Zinsmaier, K. E. (2021). Mitochondrial Miro GTPases coordinate mitochondrial and peroxisomal dynamics. Small GTPases, 12(5\u20136), 372\u2013398. https:\/\/doi.org\/10.1080\/21541248.2020.1843957","journal-title":"Small GTPases"}],"container-title":["NeuroMolecular Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12017-026-08917-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12017-026-08917-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12017-026-08917-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T00:27:12Z","timestamp":1772843232000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12017-026-08917-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,7]]},"references-count":102,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["8917"],"URL":"https:\/\/doi.org\/10.1007\/s12017-026-08917-w","relation":{},"ISSN":["1559-1174"],"issn-type":[{"value":"1559-1174","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,7]]},"assertion":[{"value":"1 January 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval and Consent to Participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}}],"article-number":"15"}}