{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T21:25:37Z","timestamp":1789248337522,"version":"build-2803163510"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2013,5,14]],"date-time":"2013-05-14T00:00:00Z","timestamp":1368489600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endocrine"],"published-print":{"date-parts":[[2014,2]]},"DOI":"10.1007\/s12020-013-9981-3","type":"journal-article","created":{"date-parts":[[2013,5,13]],"date-time":"2013-05-13T15:55:41Z","timestamp":1368460541000},"page":"114-121","source":"Crossref","is-referenced-by-count":22,"title":["Evaluation of thyroid diseases and differentiated thyroid cancer in acromegalic patients"],"prefix":"10.1007","volume":"45","author":[{"given":"Serkan","family":"Dogan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aysegul","family":"Atmaca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selcuk","family":"Dagdelen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Belkis","family":"Erbas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomris","family":"Erbas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,5,14]]},"reference":[{"key":"9981_CR1","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1056\/NEJM199004053221405","volume":"322","author":"S Melmed","year":"1990","unstructured":"S. Melmed, Acromegaly. N. Engl. J. Med. 322, 966\u2013967 (1990)","journal-title":"N. Engl. J. Med."},{"key":"9981_CR2","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1111\/j.1365-2265.2009.03667.x","volume":"72","author":"A Fernandez","year":"2010","unstructured":"A. Fernandez, N. Karavitaki, J.A.H. Wass, Prevalence of pituitary adenomas: a community-based, cross-sectional study in Banbury (Oxforshire, UK). Clin. Endocrinol. 72, 377\u2013382 (2010)","journal-title":"Clin. Endocrinol."},{"key":"9981_CR3","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/j.1365-2265.1980.tb03135.x","volume":"12","author":"L Alexander","year":"1980","unstructured":"L. Alexander, D. Appleton, R. Hall, W.M. Ross, R. Wilkinson, Epidemiology of acromegaly in the Newcastle region. Clin. Endocrinol. 12, 71\u201379 (1980)","journal-title":"Clin. Endocrinol."},{"key":"9981_CR4","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1111\/j.1365-2265.1987.tb00805.x","volume":"26","author":"JD Nabarro","year":"1987","unstructured":"J.D. Nabarro, Acromegaly. Clin. Endocrinol. 26, 481\u2013512 (1987)","journal-title":"Clin. Endocrinol."},{"key":"9981_CR5","doi-asserted-by":"crossref","first-page":"3411","DOI":"10.1210\/jcem.83.10.5111","volume":"83","author":"A Abosch","year":"1988","unstructured":"A. Abosch, J.B. Tyrrell, K.R. Lamborn, L.T. Hannegan, C.B. Applebury, C.B. Wilson, Transsphenoidal microsurgery for growth hormone-secreting pituitary adenomas: initial outcome and long-term results. J. Clin. Endocrinol. Metab. 83, 3411\u20133418 (1988)","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"9981_CR6","first-page":"2730","volume":"83","author":"SM Orme","year":"1998","unstructured":"S.M. Orme, R.J. McNally, R.A. Cartwright, P.E. Belchetz, Mortality and cancer incidence in acromegaly: a retrospective cohort study. United Kingdom Acromegaly Study Group. J. Clin. Endocrinol. Metab. 83, 2730\u20132734 (1998)","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"9981_CR7","first-page":"3419","volume":"83","author":"B Swearingen","year":"1998","unstructured":"B. Swearingen, F.G. Barker 2nd, L. Katznelson, B.M. Biller, S. Grinspoon, A. Klibanski, N. Moayeri, P.M. Black, N.T. Zervas, Long-term mortality after transsphenoidal surgery and adjunctive therapy for acromegaly. J. Clin. Endocrinol. Metab. 83, 3419\u20133426 (1998)","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"9981_CR8","doi-asserted-by":"crossref","first-page":"27","DOI":"10.7326\/0003-4819-97-1-27","volume":"97","author":"I Klein","year":"1982","unstructured":"I. Klein, G. Parveen, J.S. Gavaler, D.H. Vanthiel, Colonic polyps in patients with acromegaly. Ann. Intern. Med. 97, 27\u201330 (1982)","journal-title":"Ann. Intern. Med."},{"key":"9981_CR9","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1001\/archinte.1991.00400080113022","volume":"151","author":"J Barzilay","year":"1991","unstructured":"J. Barzilay, G.J. Heatley, G.W. Cushing, Benign and malignant tumors in patients with acromegaly. Arch. Intern. Med. 151, 1629\u20131632 (1991)","journal-title":"Arch. Intern. Med."},{"key":"9981_CR10","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1210\/jcem-72-2-245","volume":"72","author":"S Ezzat","year":"1991","unstructured":"S. Ezzat, S. Melmed, Are patients with acromegaly at increased risk for neoplasia? J. Clin. Endocrinol. Metab. 72, 245\u2013249 (1991)","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"68","key":"9981_CR11","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1002\/1097-0142(19911015)68:8<1673::AID-CNCR2820680802>3.0.CO;2-0","volume":"1991","author":"E Ron","year":"1991","unstructured":"E. Ron, G. Gridley, Z. Hrubec, W. Page, S. Arora, J.F. Fraumeni Jr, Acromegaly and gastrointestinal cancer. Cancer 1991(68), 1673\u20131677 (1991)","journal-title":"Cancer"},{"key":"9981_CR12","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1046\/j.1365-2265.1998.00536.x","volume":"49","author":"V Popovic","year":"1998","unstructured":"V. Popovic, S. Damjanovic, D. Micic, M. Nesovic, M. Djurovic, M. Petakov, S. Obradovic, S. Zoric, M. Simic, Z. Penezic, J. Marinkovic, Increased incidence of neoplasia in patients with pituitary adenomas. The Pituitary Study Group. Clin. Endocrinol. 49, 441\u2013445 (1998)","journal-title":"Clin. Endocrinol."},{"key":"9981_CR13","doi-asserted-by":"crossref","first-page":"S57","DOI":"10.1507\/endocrj.47.SupplMarch_S57","volume":"47","author":"Y Higuchi","year":"2000","unstructured":"Y. Higuchi, N. Saeki, T. Iuchi, Y. Uchino, I. Tatsuno, D. Uchida, T. Tanaka, Y. Noguchi, S. Nakamura, T. Yasuda, A. Yamaura, K. Sunami, Y. Oka, A. Uozumi, Incidence of malignant tumors in patients with acromegaly. Endocr. J. 47, S57\u2013S60 (2000)","journal-title":"Endocr. J."},{"key":"9981_CR14","doi-asserted-by":"crossref","first-page":"2935","DOI":"10.1210\/jcem.86.7.7634","volume":"86","author":"PJ Jenkins","year":"2001","unstructured":"P.J. Jenkins, M. Besser, Clinical perspective: acromegaly and cancer: a problem. J. Clin. Endocrinol. Metab. 86, 2935\u20132941 (2001)","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"9981_CR15","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1016\/S0140-6736(04)16081-9","volume":"363","author":"A Wolk","year":"2004","unstructured":"A. Wolk, The growth hormone and insulin-like growth factor I axis, and cancer. Lancet 363, 1336\u20131337 (2004)","journal-title":"Lancet"},{"key":"9981_CR16","doi-asserted-by":"crossref","first-page":"4054","DOI":"10.1210\/jc.2002-011841","volume":"87","author":"S Melmed","year":"2002","unstructured":"S. Melmed, F.F. Casanueva, F. Cavagnini, P. Chanson, L. Frohman, A. Grossman, K. Ho, D. Kleinberg, S. Lamberts, E. Laws, G. Lombardi, M.L. Vance, K.V. Werder, J. Wass, A. Giustina, Acromegaly Treatment Consensus Workshop Participants, Guidelines for acromegaly management. J. Clin. Endocrinol. Metab. 87, 4054\u20134058 (2002)","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"9981_CR17","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1590\/S0004-27302012000500004","volume":"56","author":"A Rogozinski","year":"2012","unstructured":"A. Rogozinski, A. Furioso, P. Glikman, M. Junco, R. Laudi, A. Reyes, A. Lowenstein, Thyroid nodules in acromegaly. Arq. Bras. Endocrinol. Metab. 56, 300\u2013304 (2012)","journal-title":"Arq. Bras. Endocrinol. Metab."},{"key":"9981_CR18","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1080\/07435800500229177","volume":"31","author":"G Siegel","year":"2005","unstructured":"G. Siegel, Y. Tomer, Is there an association between acromegaly and thyroid carcinoma? A critical review of the literature. Endocr. Res. 31, 51\u201358 (2005)","journal-title":"Endocr. Res."},{"key":"9981_CR19","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1023\/A:1015713732717","volume":"13","author":"D Baris","year":"2002","unstructured":"D. Baris, G. Gridley, E. Ron, E. Weiderpass, L. Mellemkjaer, A. Ekbom, J.H. Olsen, J.A. Baron, J.F. Fraumeni Jr, Acromegaly and cancer risk: a cohort study in Sweden and Denmark. Cancer Causes Control 13, 395\u2013400 (2002)","journal-title":"Cancer Causes Control"},{"key":"9981_CR20","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1089\/thy.1995.5.47","volume":"5","author":"C Balkany","year":"1995","unstructured":"C. Balkany, G.W. Cushing, An association between acromegaly and thyroid carcinoma. Thyroid 5, 47\u201350 (1995)","journal-title":"Thyroid"},{"key":"9981_CR21","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s11102-012-0383-y","volume":"16","author":"MCC Santos Dos","year":"2013","unstructured":"M.C.C. Dos Santos, G.C. Nascimento, A.G.C. Nascimento, V.C. Carvalho, M.H.C. Lopes, R. Montenegro, R. Montenegro Jr, L. Vilar, M.F. Albano, A.R.V. Alves, C.V. Parente, M. Dos Santos Faria, Thyroid cancer in patients with acromegaly: a case\u2013control study. Pituitary 16, 109\u2013114 (2013)","journal-title":"Pituitary"},{"key":"9981_CR22","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1055\/s-2004-817967","volume":"112","author":"BL Herrmann","year":"2004","unstructured":"B.L. Herrmann, H. Baumann, O.E. Janssen, R. Gorges, K.W. Schmid, K. Mann, Impact of disease activity on thyroid diseases in patients with acromegaly: basal evaluation and follow-up. Exp. Clin. Endocrinol. Diabetes 112, 225\u2013230 (2004)","journal-title":"Exp. Clin. Endocrinol. Diabetes"},{"key":"9981_CR23","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1365-2265.2005.02316.x","volume":"63","author":"P Tita","year":"2005","unstructured":"P. Tita, M.R. Ambrosio, C. Scollo, A. Carta, P. Gangemi, M. Bondanelli, R. Vigneri, E.C. degli Uberti, V. Pezzino, High prevalence of differentiated thyroid carcinoma in acromegaly. Clin. Endocrinol. 63, 161\u2013167 (2005)","journal-title":"Clin. Endocrinol."},{"key":"9981_CR24","first-page":"29","volume":"61","author":"A Baldys-Waligorska","year":"2010","unstructured":"A. Baldys-Waligorska, A. Krzentowska, F. Golkowski, G. Sokolowski, A. Hubalewska-Dydejczyk, The prevalence of benign and malignant neoplasms in acromegalic patients. Endokrynol. Pol. 61, 29\u201334 (2010)","journal-title":"Endokrynol. Pol."},{"key":"9981_CR25","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1007\/s11102-010-0224-9","volume":"13","author":"BE Gullu","year":"2010","unstructured":"B.E. Gullu, O. Celik, N. Gazioglu, P. Kadioglu, Thyroid cancer is the most common cancer associated with acromegaly. Pituitary 13, 242\u2013248 (2010)","journal-title":"Pituitary"},{"key":"9981_CR26","first-page":"526","volume":"85","author":"A Giustina","year":"2000","unstructured":"A. Giustina, A. Barkan, F.F. Casanueva, F. Cavagnini, L. Frohman, K. Ho, J. Veldhuis, J. Wass, K. von Werder, S. Melmed, Criteria for cure of acromegaly: a consensus statement. J. Clin. Endocrinol. Metab. 85, 526\u2013529 (2000)","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"9981_CR27","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1007\/BF03349833","volume":"18","author":"P Vitti","year":"1995","unstructured":"P. Vitti, T. Rago, S. Mazzeo, S. Brogioni, M. Lampis, A. De Liperi, C. Bartolozzi, A. Pinchera, E. Martino, Thyroid blood flow evaluation by color-flow Doppler sonography distinguishes Graves\u2019 disease from Hashimoto\u2019s thyroiditis. J. Endocrinol. Invest. 18, 857\u2013861 (1995)","journal-title":"J. Endocrinol. Invest."},{"key":"9981_CR28","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s11154-007-9063-z","volume":"9","author":"S Loeper","year":"2008","unstructured":"S. Loeper, S. Ezzat, Acromegaly: re-thinking cancer risk. Rev. Endocr. Metab. Disord. 9, 41\u201358 (2008)","journal-title":"Rev. Endocr. Metab. Disord."},{"key":"9981_CR29","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1507\/endocrj.K07E-010","volume":"55","author":"M Kurimoto","year":"2008","unstructured":"M. Kurimoto, I. Fukuda, N. Hizuka, K. Takano, The prevalence of benign and malignant tumors in patients with acromegaly. Endocr. J. 55, 67\u201371 (2008)","journal-title":"Endocr. J."},{"key":"9981_CR30","first-page":"1731","volume":"11","author":"S Eser","year":"2010","unstructured":"S. Eser, C. Yakut, R. \u00d6zdemir, H. Karakilin\u00e7, S. \u00d6zalan, S.F. Marshall, O. Karao\u011flano\u011flu, Z. Anbarcio\u011flu, N. \u00dc\u00e7\u00fcnc\u00fc, \u00dc. Akin, E. \u00d6zen, N. \u00d6zg\u00fcl, H. Anton-Culver, M. Tuncer, Cancer incidence rates in Turkey in 2006: a detailed registry based estimation. Asian Pac. J. Cancer Prev 11, 1731\u20131739 (2010)","journal-title":"Asian Pac. J. Cancer Prev"},{"key":"9981_CR31","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1530\/EJE-09-0558","volume":"161","author":"M Scacchi","year":"2009","unstructured":"M. Scacchi, M. Andrioli, C. Carzaniga, G. Vitale, M. Moro, L. Poggi, F.P. Giraldi, L.M. Fatti, F. Cavagnini, Elastosonographic evaluation of thyroid nodules in acromegaly. Eur. J. Endocrinol. 161, 607\u2013613 (2009)","journal-title":"Eur. J. Endocrinol."},{"key":"9981_CR32","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.jus.2010.09.008","volume":"13","author":"M Andrioli","year":"2010","unstructured":"M. Andrioli, M. Scacchi, C. Carzaniga, G. Vitale, M. Moro, L. Poggi, L.M. Fatti, F. Cavagnini, Thyroid nodules in acromegaly: the role of elastography. J. Ultrasound 13, 90\u201397 (2010)","journal-title":"J. Ultrasound"},{"key":"9981_CR33","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1046\/j.1365-2265.1997.1680985.x","volume":"46","author":"NW Cheung","year":"1997","unstructured":"N.W. Cheung, S.C. Boyages, The thyroid gland in acromegaly: an ultrasonographic study. Clin. Endocrinol. 46, 545\u2013549 (1997)","journal-title":"Clin. Endocrinol."},{"key":"9981_CR34","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1210\/jcem-67-5-973","volume":"67","author":"M Miyakawa","year":"1988","unstructured":"M. Miyakawa, M. Saji, T. Tsushima, K. Wakai, K. Shizume, Thyroid volume and serum thyroglobulin levels in patients with acromegaly: correlation with plasma insulin-like growth factor 1 levels. J. Clin. Endocrinol. Metab. 67, 973\u2013978 (1988)","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"23","key":"9981_CR35","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1055\/s-2007-1003632","volume":"1991","author":"C Wuster","year":"1991","unstructured":"C. Wuster, G. Steger, A. Schmelzle, J. Gottswinter, H.W. Minne, R. Ziegler, Increased incidence of euthyroid and hyperthyroid goiters independently of thyrotropin in patients with acromegaly. Horm. Metab. Res. 1991(23), 131\u2013134 (1991)","journal-title":"Horm. Metab. Res."},{"key":"9981_CR36","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1210\/endo-119-2-940","volume":"119","author":"D Tramontano","year":"1986","unstructured":"D. Tramontano, G.W. Cushing, A.C. Moses, S.H. Ingbar, Insulin-like growth factor stimulates the growth of rat thyroid cells in culture and synergizes the stimulation of DNA synthesis induced by TSH and Graves\u2019-IgG. Endocrinology 119, 940\u2013942 (1986)","journal-title":"Endocrinology"},{"key":"9981_CR37","author":"YJ Liu","year":"2013","unstructured":"Y.J. Liu, W. Qiang, J. Shi, S.Q. Lv, M.J. Ji, B.Y. Shi, Expression and significance of IGF-1 and IGF-1R in thyroid nodules. Endocrine (2013). doi: 10.1007\/s12020-012-9864-z","journal-title":"Endocrine"},{"key":"9981_CR38","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.beem.2008.08.011","volume":"22","author":"AG Renehan","year":"2008","unstructured":"A.G. Renehan, Acromegaly, growth hormone and cancer risk. Best Pract. Res. Clin. Endocrinol. Metab. 22, 639\u2013657 (2008)","journal-title":"Best Pract. Res. Clin. Endocrinol. Metab."},{"key":"9981_CR39","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/S0140-6736(08)60269-X","volume":"371","author":"A Renehan","year":"2008","unstructured":"A. Renehan, M. Tyson, M. Egger, R.F. Heller, M. Zwahlen, Body mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet 371, 569\u2013578 (2008)","journal-title":"Lancet"},{"key":"9981_CR40","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1530\/eje.1.02158","volume":"154","author":"F Pacini","year":"2006","unstructured":"F. Pacini, M. Schlumberger, H. Dralle, R. Elisei, J.W. Smit, W. Wiersinga, European thyroid cancer taskforce: European consensus for the management of patients with differentiated thyroid carcinoma of the follicular epithelium. Eur. J. Endocrinol. 154, 787\u2013803 (2006)","journal-title":"Eur. J. Endocrinol."},{"key":"9981_CR41","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1089\/thy.2009.0110","volume":"19","author":"DS Cooper","year":"2009","unstructured":"D.S. Cooper, G.M. Doherty, B.R. Haugen, R.T. Kloos, S.L. Lee, S.J. Mandel, E.L. Mazzaferri, B. McIver, F. Pacini, M. Schlumberger, S.I. Sherman, D.L. Steward, R.M. Tuttle, American Thyroid Association (ATA), Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid 19, 1167\u20131214 (2009)","journal-title":"Thyroid"}],"container-title":["Endocrine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12020-013-9981-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12020-013-9981-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12020-013-9981-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T01:56:49Z","timestamp":1559440609000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12020-013-9981-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,14]]},"references-count":41,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["9981"],"URL":"https:\/\/doi.org\/10.1007\/s12020-013-9981-3","relation":{},"ISSN":["1355-008X","1559-0100"],"issn-type":[{"value":"1355-008X","type":"print"},{"value":"1559-0100","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5,14]]}}}