{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T20:50:22Z","timestamp":1773262222940,"version":"3.50.1"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,4,8]],"date-time":"2014-04-08T00:00:00Z","timestamp":1396915200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endocrine"],"published-print":{"date-parts":[[2015,2]]},"DOI":"10.1007\/s12020-014-0244-8","type":"journal-article","created":{"date-parts":[[2014,4,7]],"date-time":"2014-04-07T15:55:26Z","timestamp":1396886126000},"page":"179-186","source":"Crossref","is-referenced-by-count":8,"title":["High-normal 2\u00a0h glucose is associated with defects of insulin secretion and predispose to diabetes in Chinese adults"],"prefix":"10.1007","volume":"48","author":[{"given":"Ziwei","family":"Lin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaowen","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lige","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuhong","family":"Hou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junling","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiping","family":"Jia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,4,8]]},"reference":[{"issue":"11","key":"244_CR1","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1001\/archinte.167.11.1145","volume":"167","author":"OH Franco","year":"2007","unstructured":"O.H. Franco, E.W. Steyerberg, F.B. Hu, J. Mackenbach, W. Nusselder, Associations of diabetes mellitus with total life expectancy and life expectancy with and without cardiovascular disease. Arch. Intern. Med. 167(11), 1145\u20131151 (2007)","journal-title":"Arch. Intern. Med."},{"issue":"Suppl","key":"244_CR2","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.1016\/S0168-8227(98)00038-2","volume":"40","author":"RR Holman","year":"1998","unstructured":"R.R. Holman, Assessing the potential for alpha-glucosidase inhibitors in prediabetic states. Diabetes Res. Clin. Pract. 40(Suppl), S21\u2013S25 (1998)","journal-title":"Diabetes Res. Clin. Pract."},{"issue":"7121","key":"244_CR3","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1038\/nature05482","volume":"444","author":"SE Kahn","year":"2006","unstructured":"S.E. Kahn, R.L. Hull, K.M. Utzschneider, Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 444(7121), 840\u2013846 (2006)","journal-title":"Nature"},{"issue":"6","key":"244_CR4","doi-asserted-by":"crossref","first-page":"e19930","DOI":"10.1371\/journal.pone.0019930","volume":"6","author":"P Boffetta","year":"2011","unstructured":"P. Boffetta, D. McLerran, Y. Chen, M. Inoue, R. Sinha, J. He, P.C. Gupta, S. Tsugane, F. Irie, A. Tamakoshi, Y.T. Gao, X.O. Shu, R. Wang, I. Tsuji, S. Kuriyama, K. Matsuo, H. Satoh, C.J. Chen, J.M. Yuan, K.Y. Yoo, H. Ahsan, W.H. Pan, D. Gu, M.S. Pednekar, S. Sasazuki, T. Sairenchi, G. Yang, Y.B. Xiang, M. Nagai, H. Tanaka, Y. Nishino, S.L. You, W.P. Koh, S.K. Park, C.Y. Shen, M. Thornquist, D. Kang, B. Rolland, Z. Feng, W. Zheng, J.D. Potter, Body mass index and diabetes in Asia: a cross-sectional pooled analysis of 900,000 individuals in the Asia cohort consortium. PLoS ONE 6(6), e19930 (2011)","journal-title":"PLoS ONE"},{"issue":"3","key":"244_CR5","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1093\/ajcn\/81.3.555","volume":"81","author":"Y Wang","year":"2005","unstructured":"Y. Wang, E.B. Rimm, M.J. Stampfer, W.C. Willett, F.B. Hu, Comparison of abdominal adiposity and overall obesity in predicting risk of type 2 diabetes among men. Am. J. Clin. Nutr. 81(3), 555\u2013563 (2005)","journal-title":"Am. J. Clin. Nutr."},{"issue":"9","key":"244_CR6","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1038\/ijo.2009.134","volume":"33","author":"Y Ye","year":"2009","unstructured":"Y. Ye, Y. Bao, X. Hou, X. Pan, H. Wu, H. Li, C. Wang, J. Tang, H. Lu, K. Xiang, W. Jia, Identification of waist circumference cutoffs for abdominal obesity in the Chinese population: a 7.8-year follow-up study in the Shanghai urban area. Int. J. Obes. (Lond.) 33(9), 1058\u20131062 (2009)","journal-title":"Int. J. Obes. (Lond.)"},{"issue":"9","key":"244_CR7","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1046\/j.1464-5491.2002.00835.x","volume":"19","author":"N Unwin","year":"2002","unstructured":"N. Unwin, J. Shaw, P. Zimmet, K.G. Alberti, Impaired glucose tolerance and impaired fasting glycaemia: the current status on definition and intervention. Diabet. Med. 19(9), 708\u2013723 (2002)","journal-title":"Diabet. Med."},{"issue":"3","key":"244_CR8","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1007\/s12020-012-9666-3","volume":"42","author":"TN Kim","year":"2012","unstructured":"T.N. Kim, M.S. Park, S.K. Lee, S.J. Yang, K.W. Lee, M. Nam, Y.S. Park, J.T. Woo, Y.S. Kim, S.H. Baik, Elevated A1C is associated with impaired early-phase insulin secretion rather than insulin resistance in Koreans at high risk for developing diabetes. Endocrine 42(3), 584\u2013591 (2012)","journal-title":"Endocrine"},{"issue":"1","key":"244_CR9","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.diabres.2009.10.007","volume":"87","author":"JE Shaw","year":"2010","unstructured":"J.E. Shaw, R.A. Sicree, P.Z. Zimmet, Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res. Clin. Pract. 87(1), 4\u201314 (2010)","journal-title":"Diabetes Res. Clin. Pract."},{"issue":"9833","key":"244_CR10","doi-asserted-by":"crossref","first-page":"2279","DOI":"10.1016\/S0140-6736(12)60283-9","volume":"379","author":"AG Tabak","year":"2012","unstructured":"A.G. Tabak, C. Herder, W. Rathmann, E.J. Brunner, M. Kivimaki, Prediabetes: a high-risk state for diabetes development. Lancet 379(9833), 2279\u20132290 (2012)","journal-title":"Lancet"},{"issue":"5","key":"244_CR11","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.1210\/jc.2012-3971","volume":"98","author":"C Bianchi","year":"2013","unstructured":"C. Bianchi, R. Miccoli, M. Trombetta, F. Giorgino, S. Frontoni, E. Faloia, G. Marchesini, M.A. Dolci, F. Cavalot, G. Cavallo, F. Leonetti, R.C. Bonadonna, S. Del Prato, Elevated 1-hour postload plasma glucose levels identify subjects with normal glucose tolerance but impaired beta-cell function, insulin resistance, and worse cardiovascular risk profile: the GENFIEV study. J. Clin. Endocrinol. Metab. 98(5), 2100\u20132105 (2013)","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"4","key":"244_CR12","doi-asserted-by":"crossref","first-page":"868","DOI":"10.2337\/dc11-2181","volume":"35","author":"MA Marini","year":"2012","unstructured":"M.A. Marini, E. Succurro, S. Frontoni, S. Mastroianni, F. Arturi, A. Sciacqua, R. Lauro, M.L. Hribal, F. Perticone, G. Sesti, Insulin sensitivity, beta-cell function, and incretin effect in individuals with elevated 1-hour postload plasma glucose levels. Diabetes Care 35(4), 868\u2013872 (2012)","journal-title":"Diabetes Care"},{"issue":"4","key":"244_CR13","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1007\/s00125-005-1701-y","volume":"48","author":"ME Piche","year":"2005","unstructured":"M.E. Piche, S. Lemieux, L. Perusse, S.J. Weisnagel, High normal 2\u00a0h plasma glucose is associated with insulin sensitivity and secretion that may predispose to type 2 diabetes. Diabetologia 48(4), 732\u2013740 (2005)","journal-title":"Diabetologia"},{"issue":"5","key":"244_CR14","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.2337\/db08-1607","volume":"58","author":"A Stancakova","year":"2009","unstructured":"A. Stancakova, M. Javorsky, T. Kuulasmaa, S.M. Haffner, J. Kuusisto, M. Laakso, Changes in insulin sensitivity and insulin release in relation to glycemia and glucose tolerance in 6,414 Finnish men. Diabetes 58(5), 1212\u20131221 (2009)","journal-title":"Diabetes"},{"issue":"2","key":"244_CR15","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1210\/jc.2004-1258","volume":"90","author":"CW Yeckel","year":"2005","unstructured":"C.W. Yeckel, S.E. Taksali, J. Dziura, R. Weiss, T.S. Burgert, R.S. Sherwin, W.V. Tamborlane, S. Caprio, The normal glucose tolerance continuum in obese youth: evidence for impairment in beta-cell function independent of insulin resistance. J. Clin. Endocrinol. Metab. 90(2), 747\u2013754 (2005)","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"1\u20133","key":"244_CR16","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s12020-008-9106-6","volume":"34","author":"J Hong","year":"2008","unstructured":"J. Hong, Y.F. Zhang, W.Q. Gu, Y.W. Zhang, Y.X. Su, Z.N. Chi, W.Q. Wang, X.Y. Li, G. Ning, Insulin sensitivity and first-phase insulin secretion in obese Chinese with hyperglycemia in 30 and\/or 60\u00a0min during glucose tolerance tests. Endocrine 34(1\u20133), 75\u201380 (2008)","journal-title":"Endocrine"},{"key":"244_CR17","author":"JB Su","year":"2013","unstructured":"J.B. Su, T. Chen, F. Xu, X.Q. Wang, J.F. Chen, G. Wu, Y. Jin, X.H. Wang, Glycemic variability in normal glucose regulation subjects with elevated 1-h postload plasma glucose levels. Endocrine (2013). doi: 10.1007\/s12020-013-0047-3","journal-title":"Endocrine"},{"issue":"3","key":"244_CR18","doi-asserted-by":"crossref","first-page":"606","DOI":"10.2337\/db11-1111","volume":"61","author":"C Giannini","year":"2012","unstructured":"C. Giannini, R. Weiss, A. Cali, R. Bonadonna, N. Santoro, B. Pierpont, M. Shaw, S. Caprio, Evidence for early defects in insulin sensitivity and secretion before the onset of glucose dysregulation in obese youths: a longitudinal study. Diabetes 61(3), 606\u2013614 (2012)","journal-title":"Diabetes"},{"key":"244_CR19","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1111\/nyas.12098","volume":"1281","author":"RC Ma","year":"2013","unstructured":"R.C. Ma, J.C. Chan, Type 2 diabetes in East Asians: similarities and differences with populations in Europe and the United States. Ann. N. Y. Acad. Sci. 1281, 64\u201391 (2013)","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"244_CR20","doi-asserted-by":"crossref","first-page":"213","DOI":"10.2147\/CLEP.S31830","volume":"4","author":"V Hjellvik","year":"2012","unstructured":"V. Hjellvik, S. Sakshaug, H. Strom, Body mass index, triglycerides, glucose, and blood pressure as predictors of type 2 diabetes in a middle-aged Norwegian cohort of men and women. Clin. Epidemiol. 4, 213\u2013224 (2012)","journal-title":"Clin. Epidemiol."},{"issue":"Suppl 1","key":"244_CR21","doi-asserted-by":"crossref","first-page":"S212","DOI":"10.2337\/diabetes.51.2007.S212","volume":"51","author":"RN Bergman","year":"2002","unstructured":"R.N. Bergman, M. Ader, K. Huecking, G. Van Citters, Accurate assessment of beta-cell function: the hyperbolic correction. Diabetes 51(Suppl 1), S212\u2013S220 (2002)","journal-title":"Diabetes"},{"issue":"11","key":"244_CR22","first-page":"1663","volume":"42","author":"SE Kahn","year":"1993","unstructured":"S.E. Kahn, R.L. Prigeon, D.K. McCulloch, E.J. Boyko, R.N. Bergman, M.W. Schwartz, J.L. Neifing, W.K. Ward, J.C. Beard, J.P. Palmer et al., Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function. Diabetes 42(11), 1663\u20131672 (1993)","journal-title":"Evidence for a hyperbolic function. Diabetes"},{"issue":"2","key":"244_CR23","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1007\/s00125-006-0503-1","volume":"50","author":"WP Jia","year":"2007","unstructured":"W.P. Jia, C. Pang, L. Chen, Y.Q. Bao, J.X. Lu, H.J. Lu, J.L. Tang, Y.M. Wu, Y.H. Zuo, S.Y. Jiang, K.S. Xiang, Epidemiological characteristics of diabetes mellitus and impaired glucose regulation in a Chinese adult population: the Shanghai Diabetes Studies, a cross-sectional 3-year follow-up study in Shanghai urban communities. Diabetologia 50(2), 286\u2013292 (2007)","journal-title":"Diabetologia"},{"issue":"3","key":"244_CR24","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0895-3988(10)60049-9","volume":"23","author":"C Wang","year":"2010","unstructured":"C. Wang, X.H. Hou, M.L. Zhang, Y.Q. Bao, Y.H. Zou, W.H. Zhong, K.S. Xiang, W.P. Jia, Comparison of body mass index with body fat percentage in the evaluation of obesity in Chinese. Biomed. Environ. Sci. 23(3), 173\u2013179 (2010)","journal-title":"Biomed. Environ. Sci."},{"issue":"7","key":"244_CR25","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1007\/BF00280883","volume":"28","author":"DR Matthews","year":"1985","unstructured":"D.R. Matthews, J.P. Hosker, A.S. Rudenski, B.A. Naylor, D.F. Treacher, R.C. Turner, Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28(7), 412\u2013419 (1985)","journal-title":"Diabetologia"},{"issue":"3","key":"244_CR26","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1172\/JCI105534","volume":"46","author":"HS Seltzer","year":"1967","unstructured":"H.S. Seltzer, E.W. Allen, A.L. Herron Jr., M.T. Brennan, Insulin secretion in response to glycemic stimulus: relation of delayed initial release to carbohydrate intolerance in mild diabetes mellitus. J. Clin. Invest. 46(3), 323\u2013335 (1967)","journal-title":"J. Clin. Invest."},{"issue":"4","key":"244_CR27","doi-asserted-by":"crossref","first-page":"796","DOI":"10.2337\/diacare.24.4.796","volume":"24","author":"M Stumvoll","year":"2001","unstructured":"M. Stumvoll, T. Van Haeften, A. Fritsche, J. Gerich, Oral glucose tolerance test indexes for insulin sensitivity and secretion based on various availabilities of sampling times. Diabetes Care 24(4), 796\u2013797 (2001)","journal-title":"Diabetes Care"},{"issue":"3","key":"244_CR28","doi-asserted-by":"crossref","first-page":"295","DOI":"10.2337\/diacare.23.3.295","volume":"23","author":"M Stumvoll","year":"2000","unstructured":"M. Stumvoll, A. Mitrakou, W. Pimenta, T. Jenssen, H. Yki-Jarvinen, T. Van Haeften, W. Renn, J. Gerich, Use of the oral glucose tolerance test to assess insulin release and insulin sensitivity. Diabetes Care 23(3), 295\u2013301 (2000)","journal-title":"Diabetes Care"},{"issue":"7","key":"244_CR29","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S","volume":"15","author":"KG Alberti","year":"1998","unstructured":"K.G. Alberti, P.Z. Zimmet, Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet. Med. 15(7), 539\u2013553 (1998)","journal-title":"Diabet. Med."},{"issue":"9403","key":"244_CR30","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0140-6736(03)15268-3","volume":"363","author":"WHO expert consultation","year":"2004","unstructured":"WHO expert consultation, Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet 363(9403), 157\u2013163 (2004)","journal-title":"Lancet"},{"issue":"3","key":"244_CR31","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1007\/s12020-012-9830-9","volume":"43","author":"M Bergman","year":"2013","unstructured":"M. Bergman, Pathophysiology of prediabetes and treatment implications for the prevention of type 2 diabetes mellitus. Endocrine 43(3), 504\u2013513 (2013)","journal-title":"Endocrine"},{"issue":"3","key":"244_CR32","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1007\/s12020-013-0017-9","volume":"44","author":"M Bergman","year":"2013","unstructured":"M. Bergman, Inadequacies of current approaches to prediabetes and diabetes prevention. Endocrine 44(3), 623\u2013633 (2013)","journal-title":"Endocrine"},{"issue":"Suppl 1","key":"244_CR33","doi-asserted-by":"crossref","first-page":"S160","DOI":"10.2337\/diabetes.50.2007.S160","volume":"50","author":"D Porte Jr.","year":"2001","unstructured":"D. Porte Jr., S.E. Kahn, Beta-cell dysfunction and failure in type 2 diabetes: potential mechanisms. Diabetes 50(Suppl 1), S160\u2013S163 (2001)","journal-title":"Diabetes"},{"issue":"3","key":"244_CR34","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1002\/dmrr.198","volume":"17","author":"S Prato Del","year":"2001","unstructured":"S. Del Prato, A. Tiengo, The importance of first-phase insulin secretion: implications for the therapy of type 2 diabetes mellitus. Diabetes Metab. Res. Rev. 17(3), 164\u2013174 (2001)","journal-title":"Diabetes Metab. Res. Rev."},{"issue":"3","key":"244_CR35","doi-asserted-by":"crossref","first-page":"456","DOI":"10.2337\/dc08-1274","volume":"32","author":"AM Cali","year":"2009","unstructured":"A.M. Cali, C.D. Man, C. Cobelli, J. Dziura, A. Seyal, M. Shaw, K. Allen, S. Chen, S. Caprio, Primary defects in beta-cell function further exacerbated by worsening of insulin resistance mark the development of impaired glucose tolerance in obese adolescents. Diabetes Care 32(3), 456\u2013461 (2009)","journal-title":"Diabetes Care"},{"issue":"9 Suppl 6","key":"244_CR36","doi-asserted-by":"crossref","first-page":"S109","DOI":"10.1002\/dme.1996.13.s6.109","volume":"13","author":"K Kosaka","year":"1996","unstructured":"K. Kosaka, T. Kuzuya, R. Hagura, H. Yoshinaga, Insulin response to oral glucose load is consistently decreased in established non-insulin-dependent diabetes mellitus: the usefulness of decreased early insulin response as a predictor of non-insulin-dependent diabetes mellitus. Diabet. Med. 13(9 Suppl 6), S109\u2013S119 (1996)","journal-title":"Diabet. Med."},{"issue":"2 Pt 1","key":"244_CR37","first-page":"E241","volume":"257","author":"L Luzi","year":"1989","unstructured":"L. Luzi, R.A. DeFronzo, Effect of loss of first-phase insulin secretion on hepatic glucose production and tissue glucose disposal in humans. Am. J. Physiol. 257(2 Pt 1), E241\u2013E246 (1989)","journal-title":"Am. J. Physiol."},{"issue":"21","key":"244_CR38","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1097\/00029330-200811010-00002","volume":"121","author":"C Pang","year":"2008","unstructured":"C. Pang, Y.Q. Bao, C. Wang, J.X. Lu, W.P. Jia, K.S. Xiang, Relationship between the level of fasting plasma glucose and beta cell functions in Chinese with or without diabetes. Chin. Med. J. (Engl.) 121(21), 2119\u20132123 (2008)","journal-title":"Chin. Med. J. (Engl.)"},{"issue":"1","key":"244_CR39","doi-asserted-by":"crossref","first-page":"166","DOI":"10.2337\/diabetes.54.1.166","volume":"54","author":"V Lyssenko","year":"2005","unstructured":"V. Lyssenko, P. Almgren, D. Anevski, R. Perfekt, K. Lahti, M. Nissen, B. Isomaa, B. Forsen, N. Homstrom, C. Saloranta, M.R. Taskinen, L. Groop, T. Tuomi, Predictors of and longitudinal changes in insulin sensitivity and secretion preceding onset of type 2 diabetes. Diabetes 54(1), 166\u2013174 (2005)","journal-title":"Diabetes"},{"issue":"6","key":"244_CR40","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1172\/JCI7231","volume":"104","author":"C Weyer","year":"1999","unstructured":"C. Weyer, C. Bogardus, D.M. Mott, R.E. Pratley, The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. J. Clin. Invest. 104(6), 787\u2013794 (1999)","journal-title":"J. Clin. Invest."},{"issue":"3","key":"244_CR41","doi-asserted-by":"crossref","first-page":"868","DOI":"10.2337\/diacare.26.3.868","volume":"26","author":"M Hanefeld","year":"2003","unstructured":"M. Hanefeld, C. Koehler, K. Fuecker, E. Henkel, F. Schaper, T. Temelkova-Kurktschiev, Insulin secretion and insulin sensitivity pattern is different in isolated impaired glucose tolerance and impaired fasting glucose: the risk factor in impaired glucose tolerance for atherosclerosis and diabetes study. Diabetes Care 26(3), 868\u2013874 (2003)","journal-title":"Diabetes Care"},{"issue":"6","key":"244_CR42","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.2337\/db07-0954","volume":"57","author":"A Festa","year":"2008","unstructured":"A. Festa, K. Williams, A.J. Hanley, S.M. Haffner, Beta-cell dysfunction in subjects with impaired glucose tolerance and early type 2 diabetes: comparison of surrogate markers with first-phase insulin secretion from an intravenous glucose tolerance test. Diabetes 57(6), 1638\u20131644 (2008)","journal-title":"Diabetes"},{"issue":"8","key":"244_CR43","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.2337\/dc06-0438","volume":"29","author":"C Meyer","year":"2006","unstructured":"C. Meyer, W. Pimenta, H.J. Woerle, T. Van Haeften, E. Szoke, A. Mitrakou, J. Gerich, Different mechanisms for impaired fasting glucose and impaired postprandial glucose tolerance in humans. Diabetes Care 29(8), 1909\u20131914 (2006)","journal-title":"Diabetes Care"},{"issue":"Suppl 1","key":"244_CR44","doi-asserted-by":"crossref","first-page":"S67","DOI":"10.2337\/dc13-S067","volume":"36","author":"American Diabetes Association","year":"2013","unstructured":"American Diabetes Association, Diagnosis and classification of diabetes mellitus. Diabetes Care 36(Suppl 1), S67\u2013S74 (2013)","journal-title":"Diabetes Care"},{"issue":"4","key":"244_CR45","doi-asserted-by":"crossref","first-page":"902","DOI":"10.2337\/diacare.28.4.902","volume":"28","author":"R Weiss","year":"2005","unstructured":"R. Weiss, S.E. Taksali, W.V. Tamborlane, T.S. Burgert, M. Savoye, S. Caprio, Predictors of changes in glucose tolerance status in obese youth. Diabetes Care 28(4), 902\u2013909 (2005)","journal-title":"Diabetes Care"},{"issue":"1","key":"244_CR46","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1007\/s11684-013-0262-6","volume":"7","author":"J Ye","year":"2013","unstructured":"J. Ye, Mechanisms of insulin resistance in obesity. Front Med. 7(1), 14\u201324 (2013)","journal-title":"Front Med."},{"issue":"2","key":"244_CR47","doi-asserted-by":"crossref","first-page":"76","DOI":"10.2174\/157339912799424564","volume":"8","author":"D Gupta","year":"2012","unstructured":"D. Gupta, C.B. Krueger, G. Lastra, Over-nutrition, obesity and insulin resistance in the development of beta-cell dysfunction. Curr. Diabetes Rev. 8(2), 76\u201383 (2012)","journal-title":"Curr. Diabetes Rev."},{"issue":"1","key":"244_CR48","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1210\/jc.2004-1133","volume":"90","author":"E Ferrannini","year":"2005","unstructured":"E. Ferrannini, A. Gastaldelli, Y. Miyazaki, M. Matsuda, A. Mari, R.A. DeFronzo, Beta-cell function in subjects spanning the range from normal glucose tolerance to overt diabetes: a new analysis. J. Clin. Endocrinol. Metab. 90(1), 493\u2013500 (2005)","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"5","key":"244_CR49","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1007\/s00125-012-2466-8","volume":"55","author":"JJ Meier","year":"2012","unstructured":"J.J. Meier, T.G. Breuer, R.C. Bonadonna, A. Tannapfel, W. Uhl, W.E. Schmidt, H. Schrader, B.A. Menge, Pancreatic diabetes manifests when beta cell area declines by approximately 65% in humans. Diabetologia 55(5), 1346\u20131354 (2012)","journal-title":"Diabetologia"}],"container-title":["Endocrine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12020-014-0244-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12020-014-0244-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12020-014-0244-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,9]],"date-time":"2019-08-09T05:08:22Z","timestamp":1565327302000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12020-014-0244-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,8]]},"references-count":49,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["244"],"URL":"https:\/\/doi.org\/10.1007\/s12020-014-0244-8","relation":{},"ISSN":["1355-008X","1559-0100"],"issn-type":[{"value":"1355-008X","type":"print"},{"value":"1559-0100","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,8]]}}}