{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:33:53Z","timestamp":1761744833872,"version":"3.37.3"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,10,9]],"date-time":"2018-10-09T00:00:00Z","timestamp":1539043200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"ICBM","award":["Istituto Clinico Beato Matteo"],"award-info":[{"award-number":["Istituto Clinico Beato Matteo"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Endocrine"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1007\/s12020-018-1782-2","type":"journal-article","created":{"date-parts":[[2018,10,9]],"date-time":"2018-10-09T02:48:33Z","timestamp":1539053313000},"page":"177-181","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Transmucosal oxygen tension of the clitoris: a new parameter for future investigations of the sexual, metabolic, and cardiovascular health of women"],"prefix":"10.1007","volume":"63","author":[{"given":"A","family":"Coppola","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Montalcini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Gallotti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Luzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Pujia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Giustina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9974-0735","authenticated-orcid":false,"given":"C","family":"Gazzaruso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,10,9]]},"reference":[{"key":"1782_CR1","first-page":"95","volume":"7","author":"MI Maiorino","year":"2014","unstructured":"M.I. Maiorino, G. Bellastella, K. Esposito, Diabetes and sexual dysfunction: current perspectives. Diabetes Metab. Syndr. Obes. 7, 95\u2013105 (2014)","journal-title":"Diabetes Metab. Syndr. Obes."},{"key":"1782_CR2","first-page":"S84","volume":"10","author":"I Goldstein","year":"1998","unstructured":"I. Goldstein, J.R. Berman, Vasculogenic female sexual dysfunction: vaginal engorgement and clitoral erectile insufficiency syndromes. Int. J. Impot. Res. 10, S84\u2013S89 (1998)","journal-title":"Int. J. Impot. Res."},{"key":"1782_CR3","doi-asserted-by":"publisher","unstructured":"M.I. Maiorino, G. Bellastella, D. Giugliano, K. Esposito, From inflammation to sexual dysfunctions: a journey through diabetes, obesity, and metabolic syndrome. J. Endocrinol. Invest. \n                    https:\/\/doi.org\/10.1007\/s40618-018-0872-6\n                    \n                   (2018)","DOI":"10.1007\/s40618-018-0872-6"},{"issue":"3","key":"1782_CR4","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1038\/sj.ijir.3901310","volume":"17","author":"K Esposito","year":"2005","unstructured":"K. Esposito, M. Ciotola, R. Marfella, D. Di Tommaso, L. Cobellis, D. Giugliano, The metabolic syndrome: a cause of sexual dysfunction in women. Int. J. Impot. Res. 17(3), 224\u2013226 (2005)","journal-title":"Int. J. Impot. Res."},{"issue":"8","key":"1782_CR5","doi-asserted-by":"publisher","first-page":"1511","DOI":"10.1007\/s11695-015-1721-8","volume":"25","author":"MR Janik","year":"2015","unstructured":"M.R. Janik, I. Bielecka, K. Pa\u015bnik, A. Kwiatkowski, L. Podg\u00f3rska, Female sexual function before and after bariatric surgery: a cross-sectional study and review of literature. Obes. Surg. 25(8), 1511\u20131517 (2015)","journal-title":"Obes. Surg."},{"issue":"6","key":"1782_CR6","doi-asserted-by":"publisher","first-page":"1696","DOI":"10.1111\/j.1743-6109.2009.01284.x","volume":"6","author":"K Esposito","year":"2009","unstructured":"K. Esposito, M. Ciotola, M.I. Maiorino, F. Giugliano, R. Autorino, M. De Sio, D. Cozzolino, F. Saccomanno, D. Giugliano, Hyperlipidemia and sexual function in premenopausal women. J. Sex. Med. 6(6), 1696\u20131703 (2009)","journal-title":"J. Sex. Med."},{"issue":"2","key":"1782_CR7","doi-asserted-by":"publisher","first-page":"143","DOI":"10.2174\/157339911794940693","volume":"7","author":"C Gazzaruso","year":"2011","unstructured":"C. Gazzaruso, A. Coppola, A. Giustina, Erectile dysfunction and coronary artery disease in patients with diabetes. Curr. Diabetes Rev. 7(2), 143\u2013147 (2011)","journal-title":"Curr. Diabetes Rev."},{"issue":"5","key":"1782_CR8","doi-asserted-by":"publisher","first-page":"968","DOI":"10.1016\/j.eururo.2013.08.023","volume":"65","author":"G Gandaglia","year":"2014","unstructured":"G. Gandaglia, A. Briganti, G. Jackson, R.A. Kloner, F. Montorsi, P. Montorsi, C. Vlachopoulos, A systematic review of the association between erectile dysfunction and cardiovascular disease. Eur. Urol. 65(5), 968\u2013978 (2014)","journal-title":"Eur. Urol."},{"issue":"3","key":"1782_CR9","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1038\/sj.ijir.3901403","volume":"18","author":"C Gazzaruso","year":"2006","unstructured":"C. Gazzaruso, A. Pujia, S.B. Solerte, E.D. Amici, E. Emanuele, C. Falcone, D. Geroldi, A. Giustina, A. Garzaniti, Erectile dysfunction and angiographic extent of coronary artery disease in type II diabetic patients. Int. J. Impot. Res. 18(3), 311\u2013315 (2006)","journal-title":"Int. J. Impot. Res."},{"issue":"21","key":"1782_CR10","doi-asserted-by":"publisher","first-page":"2040","DOI":"10.1016\/j.jacc.2007.10.069","volume":"51","author":"C Gazzaruso","year":"2008","unstructured":"C. Gazzaruso, S.B. Solerte, A. Pujia, A. Coppola, M. Vezzoli, F. Salvucci, C. Valenti, A. Giustina, Erectile dysfunction as a predictor of cardiovascular events and death in diabetic patients with angiographically proven asymptomatic coronary artery disease: A potential protective role for statins and 5-phosphodiesterase inhibitors. J. Am. Coll. Cardiol. 51(21), 2040\u20132044 (2008).","journal-title":"J. Am. Coll. Cardiol."},{"issue":"2","key":"1782_CR11","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1007\/s12020-011-9523-9","volume":"40","author":"C Gazzaruso","year":"2011","unstructured":"C. Gazzaruso, A. Coppola, T. Montalcini, C. Valenti, A. Garzaniti, G. Pelissero, F. Salvucci, P. Gallotti, A. Pujia, C. Falcone, S.B. Solerte, A. Giustina, Erectile dysfunction can improve the effectiveness of the current guidelines for the screening for asymptomatic coronary artery disease in diabetes. Endocrine 40(2), 273\u2013279 (2011).","journal-title":"Endocrine"},{"issue":"6","key":"1782_CR12","first-page":"552","volume":"13","author":"C Gazzaruso","year":"2016","unstructured":"C. Gazzaruso, A. Coppola, A. Pujia, C. Falcone, S. Collaviti, M. Fodaro, P. Gallotti, S.B. Solerte, A. Giustina, G. Pelissero, L. Luzi, T. Montalcini, Erectile dysfunction as a predictor of asymptomatic coronary artery disease in elderly men with type 2 diabetes. J. Geriatr. Cardiol. 13(6), 552\u2013556 (2016)","journal-title":"J. Geriatr. Cardiol."},{"issue":"2","key":"1782_CR13","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1111\/jsm.12392","volume":"11","author":"C Battaglia","year":"2014","unstructured":"C. Battaglia, E. Morotti, N. Persico, B. Battaglia, P. Busacchi, P. Casadio, R. Paradisi, S. Venturoli, Clitoral vascularization and sexual behavior in young patients treated with drospirenone-ethinyl estradiol or contraceptive vaginal ring: a prospective, randomized, pilot study. J. Sex. Med. 11(2), 471\u2013480 (2014)","journal-title":"J. Sex. Med."},{"issue":"6","key":"1782_CR14","doi-asserted-by":"publisher","first-page":"1717","DOI":"10.1111\/j.1743-6109.2011.02257.x","volume":"8","author":"C Battaglia","year":"2011","unstructured":"C. Battaglia, B. Battaglia, F. Mancini, N. Persico, R.E. Nappi, R. Paradisi, S. Venturoli, Cigarette smoking decreases the genital vascularization in young healthy, eumenorrheic women. J. Sex. Med. 8(6), 1717\u20131725 (2011)","journal-title":"J. Sex. Med."},{"issue":"8","key":"1782_CR15","doi-asserted-by":"publisher","first-page":"2334","DOI":"10.1111\/j.1743-6109.2011.02310.x","volume":"8","author":"C Battaglia","year":"2011","unstructured":"C. Battaglia, B. Battaglia, F. Mancini, R.E. Nappi, R. Paradisi, S. Venturoli, Moderate alcohol intake, genital vascularization, and sexuality in young, healthy, eumenorrheic women. A pilot study. J. Sex. Med. 8(8), 2334\u20132343 (2011)","journal-title":"J. Sex. Med."},{"issue":"11","key":"1782_CR16","doi-asserted-by":"publisher","first-page":"1651","DOI":"10.1016\/j.jsxm.2016.09.009","volume":"13","author":"E Maseroli","year":"2016","unstructured":"E. Maseroli, E. Fanni, S. Cipriani, I. Scavello, F. Pampaloni, C. Battaglia, M. Fambrini, E. Mannucci, E.A. Jannini, M. Maggi, L. Vignozzi, Cardiometabolic risk and female sexuality: focus on clitoral vascular resistance. J. Sex. Med. 13(11), 1651\u20131661 (2016)","journal-title":"J. Sex. Med."},{"issue":"Suppl 1","key":"1782_CR17","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1007\/s00772-018-0368-x","volume":"23","author":"U Rother","year":"2018","unstructured":"U. Rother, W. Lang, Noninvasive measurements of tissue perfusion in critical limb ischemia. Gefasschirurgie 23(Suppl 1), 8\u201312 (2018)","journal-title":"Gefasschirurgie"},{"issue":"1","key":"1782_CR18","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1007\/s12020-011-9544-4","volume":"41","author":"C Gazzaruso","year":"2012","unstructured":"C. Gazzaruso, A. Coppola, T. Montalcini, E. Baffero, A. Garzaniti, G. Pelissero, S. Collaviti, A. Grugnetti, P. Gallotti, A. Pujia, S.B. Solerte, A. Giustina, Lipoprotein(a) and homocysteine as genetic risk factors for vascular and neuropathic diabetic foot in type 2 diabetes mellitus. Endocrine 41(1), 89\u201395 (2012)","journal-title":"Endocrine"},{"issue":"6","key":"1782_CR19","doi-asserted-by":"publisher","first-page":"1720","DOI":"10.2337\/dc12-1401","volume":"36","author":"C Gazzaruso","year":"2013","unstructured":"C. Gazzaruso, A. Coppola, C. Falcone, C. Luppi, T. Montalcini, E. Baffero, P. Gallotti, A. Pujia, S.B. Solerte, G. Pelissero, A. Giustina, Transcutaneous oxygen tension as a potential predictor of cardiovascular events in type 2 diabetes: comparison with ankle\u2013brachial index. Diabetes Care 36(6), 1720\u20131725 (2013)","journal-title":"Diabetes Care"},{"issue":"8","key":"1782_CR20","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1007\/s00592-018-1145-8","volume":"55","author":"K Fagher","year":"2018","unstructured":"K. Fagher, P. Katzman, M. L\u00f6ndahl, Transcutaneous oxygen pressure as a predictor for short-term survival in patients with type 2 diabetes and foot ulcers: a comparison with ankle\u2013brachial index and toe blood pressure. Acta Diabetol. 55(8), 781\u2013788 (2018)","journal-title":"Acta Diabetol."},{"issue":"1","key":"1782_CR21","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1007\/s12020-015-0775-7","volume":"53","author":"A Coppola","year":"2016","unstructured":"A. Coppola, L. Sasso, A. Bagnasco, A. Giustina, C. Gazzaruso, The role of patient education in the prevention and management of type 2 diabetes: an overview. Endocrine 53(1), 18\u201327 (2016)","journal-title":"Endocrine"},{"issue":"10","key":"1782_CR22","doi-asserted-by":"publisher","first-page":"195","DOI":"10.21037\/atm.2018.03.30","volume":"6","author":"C Gazzaruso","year":"2018","unstructured":"C. Gazzaruso, A. Coppola, T. Montalcini, C. Falcone, Anti-diabetic agents and heart health: how to use new diabetes medications in a global strategy for the prevention of cardiovascular complications in type 2 diabetes. Ann. Transl. Med. 6(10), 195 (2018)","journal-title":"Ann. Transl. Med."},{"issue":"3","key":"1782_CR23","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1007\/s11739-011-0527-5","volume":"7","author":"C Gazzaruso","year":"2012","unstructured":"C. Gazzaruso, A. Coppola, T. Montalcini, C. Valenti, G. Pelissero, S.B. Solerte, F. Salvucci, P. Gallotti, A. Pujia, A. Garzaniti, A. Giustina, Screening for asymptomatic coronary artery disease can reduce cardiovascular mortality and morbidity in type 2 diabetic patients. Intern. Emerg. Med. 7(3), 257\u2013266 (2012)","journal-title":"Intern. Emerg. Med."}],"container-title":["Endocrine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12020-018-1782-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12020-018-1782-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12020-018-1782-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,8]],"date-time":"2019-10-08T19:13:37Z","timestamp":1570562017000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12020-018-1782-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,9]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["1782"],"URL":"https:\/\/doi.org\/10.1007\/s12020-018-1782-2","relation":{},"ISSN":["1355-008X","1559-0100"],"issn-type":[{"type":"print","value":"1355-008X"},{"type":"electronic","value":"1559-0100"}],"subject":[],"published":{"date-parts":[[2018,10,9]]},"assertion":[{"value":"30 August 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 October 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 October 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The informed consent was obtained from all the subjects recruited in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained by all the subjects recruited in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}