{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T02:00:39Z","timestamp":1783821639322,"version":"3.55.0"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,4,14]],"date-time":"2021-04-14T00:00:00Z","timestamp":1618358400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,4,14]],"date-time":"2021-04-14T00:00:00Z","timestamp":1618358400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Endocrine"],"published-print":{"date-parts":[[2021,7]]},"DOI":"10.1007\/s12020-021-02701-5","type":"journal-article","created":{"date-parts":[[2021,4,14]],"date-time":"2021-04-14T08:02:31Z","timestamp":1618387351000},"page":"166-176","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Outcome of pituitary hormone deficits after surgical treatment of nonfunctioning pituitary macroadenomas"],"prefix":"10.1007","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9933-7188","authenticated-orcid":false,"given":"Orsalia","family":"Alexopoulou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Everard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martine","family":"Etoa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Fomekong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Gaillard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrice","family":"Parker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Raftopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Chanson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Maiter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,4,14]]},"reference":[{"key":"2701_CR1","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1001\/jama.2016.19699","volume":"317","author":"ME Molitch","year":"2017","unstructured":"M.E. Molitch, Diagnosis and treatment of pituitary adenomas. A review. JAMA 317, 516\u2013524 (2017). https:\/\/doi.org\/10.1001\/jama.2016.19699","journal-title":"JAMA"},{"key":"2701_CR2","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1016\/j.beem.2009.05.005","volume":"23","author":"Y Greenman","year":"2009","unstructured":"Y. Greenman, N. Stern, Non-functioning pituitary adenomas. Best. Pract. Res. Clin. Endocrinol. Metab. 23, 625\u2013638 (2009). https:\/\/doi.org\/10.1016\/j.beem.2009.05.005","journal-title":"Best. Pract. Res. Clin. Endocrinol. Metab."},{"key":"2701_CR3","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1007\/s11102-006-0412-9","volume":"9","author":"CA Jaffe","year":"2006","unstructured":"C.A. Jaffe, Clinically non-functioning pituitary adenoma. Pituitary 9, 317\u2013321 (2006). https:\/\/doi.org\/10.1007\/s11102-006-0412-9","journal-title":"Pituitary"},{"key":"2701_CR4","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1530\/EJE-15-0967","volume":"174","author":"G Ntali","year":"2016","unstructured":"G. Ntali, C. Capatina, V. Fazal-Sanderson, J.V. Byrne, S. Cudlip, A.B. Grossman, J.A. Wass, N. Karavitaki, Mortality in patients with non-functioning pituitary adenoma is increased: systematic analysis of 546 cases with long follow-up. Eur. J. Endocrinol. 174, 137\u2013145 (2016). https:\/\/doi.org\/10.1530\/EJE-15-0967","journal-title":"Eur. J. Endocrinol."},{"key":"2701_CR5","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/j.ando.2015.04.002","volume":"76","author":"P Chanson","year":"2015","unstructured":"P. Chanson, G. Raverot, F. Castinetti, C. Cortet-Rudelli, F. Galland, S. Salenave, French Endocrinology Society non-functioning pituitary adenoma work-group. Management of clinically non-functioning pituitary adenoma. Ann. Endocrinol. 76, 239\u2013247 (2015). https:\/\/doi.org\/10.1016\/j.ando.2015.04.002","journal-title":"Ann. Endocrinol."},{"key":"2701_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1210\/jendso\/bvaa021","volume":"4","author":"PU Freda","year":"2020","unstructured":"P.U. Freda, J.N. Bruce, A.G. Khandji, Z. Jin, R.A. Hickman, E. Frey, C. Reyes-Vidal, M. Otten, S.L. Wardlaw, K.D. Post, Presenting features in 269 patients with clinically non functioning pituitary adenomas enrolled in a prospective study. J. Endocr. Soc. 4, 1\u201313 (2020). https:\/\/doi.org\/10.1210\/jendso\/bvaa021","journal-title":"J. Endocr. Soc."},{"key":"2701_CR7","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1210\/jcem.85.1.6309","volume":"85","author":"MR Drange","year":"2000","unstructured":"M.R. Drange, N.R. Fram, V. Herman-Bonert, S. Melmed, Pituitary tumor registry: a novel clinical resource. J. Clin. Endocrinol. Metab. 85, 168\u2013174 (2000). https:\/\/doi.org\/10.1210\/jcem.85.1.6309","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"2701_CR8","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1227\/01.NEU.0000325725.77132.90","volume":"63","author":"N Fatemi","year":"2008","unstructured":"N. Fatemi, J.R. Dusick, C. Mattozo, D.L. McArthur, P. Cohan, J. Boscardin, C. Wang, R.S. Swerdloff, D.F. Kelly, Pituitary hormonal loss and recovery after transsphenoidal adenoma removal. Neurosurgery 63, 709\u2013718 (2008). https:\/\/doi.org\/10.1227\/01.NEU.0000325725.77132.90","journal-title":"Neurosurgery"},{"key":"2701_CR9","doi-asserted-by":"publisher","first-page":"3696","DOI":"10.1210\/jcem.84.10.6019","volume":"84","author":"SM Webb","year":"1999","unstructured":"S.M. Webb, M. Rigla, A. W\u00e4gner, B. Oliver, F. Bartumeus, Recovery of hypopituitarism after neurosurgical treatment of pituitary adenomas. J. Clin. Endocrinol. Metab. 84, 3696\u20133700 (1999). https:\/\/doi.org\/10.1210\/jcem.84.10.6019","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"2701_CR10","doi-asserted-by":"publisher","first-page":"3717","DOI":"10.1210\/jc.2008-0643","volume":"93","author":"OM Dekkers","year":"2008","unstructured":"O.M. Dekkers, A.M. Pereira, J.A. Romijn, Treatment and follow-up of clinically nonfunctioning pituitary macroadenomas. J. Clin. Endocrinol. Metab. 93, 3717\u20133726 (2008). https:\/\/doi.org\/10.1210\/jc.2008-0643","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"2701_CR11","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/j.ando.2015.04.005","volume":"76","author":"G Raverot","year":"2015","unstructured":"G. Raverot, G. Assi\u00e9, F. Cotton, M. Cogne, A. Boulin, M. Dherbomez, J.F. Bonneville, C. Massart, Biological and radiological exploration and management of non-functioning pituitary adenoma. Ann. Endocrinol. 76, 201\u2013209 (2015). https:\/\/doi.org\/10.1016\/j.ando.2015.04.005","journal-title":"Ann. Endocrinol."},{"key":"2701_CR12","doi-asserted-by":"publisher","first-page":"894","DOI":"10.1210\/jc.2010-1048","volume":"96","author":"PU Freda","year":"2011","unstructured":"P.U. Freda, A.M. Beckers, L. Katznelson, M.E. Molitch, V.M. Montori, K.D. Post, M.L. Vance, Endocrine Society.Pituitary incidentaloma: an endocrine society clinical practice guideline. J. Clin. Endocrinol. Metab. 96, 894\u2013904 (2011). https:\/\/doi.org\/10.1210\/jc.2010-1048","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"2701_CR13","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1227\/NEU.0000000000001389","volume":"79","author":"JW Lucas","year":"2016","unstructured":"J.W. Lucas, M.E. Bodach, L.M. Tumialan, N.M. Oyesiku, C.G. Patil, Z. Litvack, M.K. Aghi, G. Zada,, Congress of neurological surgeons systematic review and evidence-based guideline on primary management of patients with nonfunctioning pituitary adenomas. Neurosurgery 79, 533\u2013535 (2016). https:\/\/doi.org\/10.1227\/NEU.0000000000001389","journal-title":"Neurosurgery"},{"key":"2701_CR14","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1227\/01.NEU.0000255459.14764.BA","volume":"60","author":"P Mortini","year":"2007","unstructured":"P. Mortini, R. Barzaghi, M. Losa, N. Boari, M. Giovanelli, Surgical treatment of giant pituitary adenomas: strategies and results in a series of 95 consecutive patients. Neurosurgery 60, 993\u20131002 (2007). https:\/\/doi.org\/10.1227\/01.NEU.0000255459.14764.BA","journal-title":"Neurosurgery"},{"key":"2701_CR15","doi-asserted-by":"publisher","first-page":"1796","DOI":"10.1210\/jc.2005-2552","volume":"91","author":"OM Dekkers","year":"2006","unstructured":"O.M. Dekkers, A.M. Pereira, F. Roelfsema, J.H. Voormolen, K.J. Neelis, M.A. Schroijen, J.W. Smit, J.A. Romijn, Observation alone after transsphenoidal surgery for nonfunctioning pituitary macroadenoma. J. Clin. Endocrinol. Metab. 91, 1796\u20131801 (2006). https:\/\/doi.org\/10.1210\/jc.2005-2552","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"2701_CR16","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1007\/s11102-017-0854-2","volume":"21","author":"DL Penn","year":"2018","unstructured":"D.L. Penn, W.T. Burke, E.R. Laws, Management of non-functioning pituitary adenomas: surgery. Pituitary 21, 145\u2013153 (2018). https:\/\/doi.org\/10.1007\/s11102-017-0854-2","journal-title":"Pituitary"},{"key":"2701_CR17","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1007\/s00701-003-0174-3","volume":"146","author":"P Nomikos","year":"2004","unstructured":"P. Nomikos, C. Ladar, R. Fahlbusch, M. Buchfelder, Impact of primary surgery on pituitary function in patients with non-functioning pituitary adenomas\u2014a study on 721 patients. Acta Neurochir. 146, 27\u201335 (2004). https:\/\/doi.org\/10.1007\/s00701-003-0174-3","journal-title":"Acta Neurochir."},{"key":"2701_CR18","doi-asserted-by":"publisher","first-page":"589","DOI":"10.3171\/2015.1.JNS141543","volume":"124","author":"A Jahangiri","year":"2016","unstructured":"A. Jahangiri, J.R. Wagner, S.W. Han, M.T. Tran, L.M. Miller, R. Chen, M.W. Tom, L.R. Ostling, S. Kunwar, L. Blevins, M.K. Aghi, Improved versus worsened endocrine function after transsphenoidal surgery for non functional pituitary adenomas: rate, time course, and radiological analysis. J. Neurosurg. 124, 589\u2013595 (2016). https:\/\/doi.org\/10.3171\/2015.1.JNS141543","journal-title":"J. Neurosurg."},{"key":"2701_CR19","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/j.wneu.2017.09.194","volume":"109","author":"JH Kim","year":"2018","unstructured":"J.H. Kim, J.H. Lee, J.H. Lee, A.R. Hong, Y.J. Kim, Y.H. Kim, Endoscopic transsphenoidal surgery outcomes in 331 nonfunctioning pituitary adenoma cases after a single surgeon learning curve. World Neurosurg. 109, 409\u2013416 (2018). https:\/\/doi.org\/10.1016\/j.wneu.2017.09.194","journal-title":"World Neurosurg."},{"key":"2701_CR20","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1530\/EJE-10-0255","volume":"163","author":"S Brochier","year":"2010","unstructured":"S. Brochier, F. Galland, M. Kujas, F. Parker, S. Gaillard, C. Raftopoulos, J. Young, O. Alexopoulou, D. Maiter, P. Chanson, Factors predicting relapse of nonfunctioning pituitary macroadenomas after neurosurgery: a study of 142 patients. Eur. J. Endocrinol. 163, 193\u2013200 (2010). https:\/\/doi.org\/10.1530\/EJE-10-0255","journal-title":"Eur. J. Endocrinol."},{"key":"2701_CR21","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1159\/000491388","volume":"7","author":"L Persani","year":"2018","unstructured":"L. Persani, G. Brabant, M. Dattani, M. Bonomi, U. Feldt-Rasmussen, E. Fliers, A. Gruters, D. Maiter, N. Schoenmakers, A.S.P. van Trotsenburg, 2018 European Thyroid Association (ETA) guidelines on the diagnosis and management of central hypothyroidism. Eur. Thyroid J. 7, 225\u2013237 (2018). https:\/\/doi.org\/10.1159\/000491388","journal-title":"Eur. Thyroid J."},{"key":"2701_CR22","doi-asserted-by":"publisher","first-page":"4245","DOI":"10.1210\/jc.2008-0710","volume":"93","author":"R Kazlauskaite","year":"2008","unstructured":"R. Kazlauskaite, A.T. Evans, C.V. Villabona, T.A.M. Abdu, B. Ambrosi, A.B. Atkinson, C.H. Choi, R.N. Clayton, C.H. Courtney, E.N. Gonc, M. Maghnie, S.R. Rose, D.G. Soule, K. Tordjman, Corticotropin tests for hypothalamic-pituitary- adrenal Insufficiency: a metaanalysis. J. Clin. Endocrinol. Metab. 93, 4245\u20134253 (2008)","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"2701_CR23","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1227\/00006123-199310000-00008","volume":"33","author":"E Knosp","year":"1993","unstructured":"E. Knosp, E. Steiner, K. Kitz, C. Matula, Pituitary adenomas with invasion of the cavernous sinus space: a magnetic resonance imaging classification compared with surgical findings. Neurosurgery 33, 610\u2013617 (1993). https:\/\/doi.org\/10.1227\/00006123-199310000-00008","journal-title":"Neurosurgery"},{"key":"2701_CR24","doi-asserted-by":"publisher","first-page":"803","DOI":"10.3171\/2014.12.JNS141083","volume":"122","author":"AS Micko","year":"2015","unstructured":"A.S. Micko, A. W\u00f6hrer, S. Wolfsberger, E. Knosp,, Invasion of the cavernous sinus space in pituitary adenomas: endoscopic verification and its correlation with an MRI-based classification. J. Neurosurg. 122, 803\u2013811 (2015). https:\/\/doi.org\/10.3171\/2014.12.JNS141083","journal-title":"J. Neurosurg."},{"key":"2701_CR25","doi-asserted-by":"publisher","unstructured":"N. Karavitaki, G. Thanabalasingham, H.C. Shore, R. Trifanescu, O. Ansorge, N. Meston, H.E. Turner, J.A. Wass, Do the limits of serum prolactin in disconnection hyperprolactinaemia need re-definition? A study 226 patients histologically verified non-functioning pituitary macroadenoma. Eur. J. Endocrinol. 65, 524\u2013529 (2006). https:\/\/doi.org\/10.1111\/j.1365-2265.2006.02627.x","DOI":"10.1111\/j.1365-2265.2006.02627.x"},{"key":"2701_CR26","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/B978-0-444-59602-4.00012-5","volume":"124","author":"ME Molitch","year":"2014","unstructured":"M.E. Molitch, Nonfunctioning pituitary tumors. Handb. Clin. Neurol. 124, 167\u2013184 (2014). https:\/\/doi.org\/10.1016\/B978-0-444-59602-4.00012-5","journal-title":"Handb. Clin. Neurol."},{"key":"2701_CR27","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.1210\/jcem-62-6-1173","volume":"62","author":"BM Arafah","year":"1986","unstructured":"B.M. Arafah, Reversible hypopituitarism in patients with large nonfunctioning pituitary adenomas. J. Clin. Endocrinol. Metab. 62, 1173\u20131179 (1986). https:\/\/doi.org\/10.1210\/jcem-62-6-1173","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"2701_CR28","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1530\/EJE-13-0515","volume":"169","author":"M Losa","year":"2013","unstructured":"M. Losa, C.A. Donofrio, R. Barzaghi, P. Mortini, Presentation and surgical results of incidentally discovered nonfunctioning pituitary adenomas: evidence for a better outcome independently of other patients\u2019 characteristics. Eur. J. Endocrinol. 169, 735\u2013742 (2013). https:\/\/doi.org\/10.1530\/EJE-13-0515","journal-title":"Eur. J. Endocrinol."},{"key":"2701_CR29","doi-asserted-by":"publisher","first-page":"1183","DOI":"10.1016\/j.wneu.2019.03.062","volume":"126","author":"R Zhang","year":"2019","unstructured":"R. Zhang, Z. Wang, L. Gao, X. Guo, C. Feng, K. Deng, W. Lian, Y. Yao, M. Feng, X. Bao, R. Wang, B. Xing, Clinical characteristics and postoperative recovery of hypopituitarism in patients with nonfunctional pituitary adenoma. World Neurosurg. 126, 1183\u20131189 (2019). https:\/\/doi.org\/10.1016\/j.wneu.2019.03.062","journal-title":"World Neurosurg."},{"key":"2701_CR30","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1007\/BF03347763","volume":"17","author":"M Marazuela","year":"1994","unstructured":"M. Marazuela, B. Astigarraga, A. Vicente, J. Estrada, C. Cuerda, J. Garc\u00eda-Ur\u00eda, T. Lucas, Recovery of visual and endocrine function following transsphenoidal surgery of large nonfunctioning pituitary adenomas. J. Endocrinol. Investig. 17, 703\u2013707 (1994). https:\/\/doi.org\/10.1007\/BF03347763","journal-title":"J. Endocrinol. Investig."},{"key":"2701_CR31","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/j.wneu.2017.09.192","volume":"109","author":"G Alzhrani","year":"2018","unstructured":"G. Alzhrani, W. Sivakumar, M.S. Park, P. Taussky, W.T. Couldwell, Delayed complications after transsphenoidal surgery for pituitary adenomas. World Neurosurg. 109, 233\u2013241 (2018). https:\/\/doi.org\/10.1016\/j.wneu.2017.09.192","journal-title":"World Neurosurg."},{"key":"2701_CR32","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1111\/j.1365-2265.2010.03875.x","volume":"73","author":"MH Murad","year":"2010","unstructured":"M.H. Murad, M.M. Fern\u00e1ndez-Balsells, A. Barwise, J.F. Gallegos-Orozco, A. Paul, M.A. Lane, J.F. Lampropulos, I. Natividad, L. Perestelo-P\u00e9rez, P.G. Ponce de Le\u00f3n-Lovat\u00f3n, F.N. Albuquerque, J. Jantey Carey, P.J. Erwin, V.M. Montori, Outcomes of surgical treatment for nonfunctioning pituitary adenomas: a systematic review and meta-analysis. Clin. Endocrinol. 73, 777\u2013791 (2010). https:\/\/doi.org\/10.1111\/j.1365-2265.2010.03875.x","journal-title":"Clin. Endocrinol"},{"key":"2701_CR33","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1007\/s00701-013-1959-7","volume":"156","author":"H Halvorsen","year":"2014","unstructured":"H. Halvorsen, J. Ramm-Pettersen, R. Josefsen, P. R\u00f8nning, S. Reinlie, T. Meling, J. Berg-Johnsen, J. Bollerslev, E. Helseth, Surgical complications after transsphenoidal microscopic and endoscopic surgery for pituitary adenoma: a consecutive series of 506 procedures. Acta Neurochir. 156, 441\u2013449 (2014). https:\/\/doi.org\/10.1007\/s00701-013-1959-7","journal-title":"Acta Neurochir."},{"key":"2701_CR34","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1007\/s11102-011-0347-7","volume":"15","author":"F Roelfsema","year":"2012","unstructured":"F. Roelfsema, N.R. Biermasz, A.M. Pereira, Clinical factors involved in the recurrence of pituitary adenomas after surgical remission: a structured review and meta-analysis. Pituitary 15, 71\u201383 (2012). https:\/\/doi.org\/10.1007\/s11102-011-0347-7","journal-title":"Pituitary"},{"key":"2701_CR35","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1002\/1097-0142(19910815)68:4<860::aid-cncr2820680431>3.0.co;2-4","volume":"68","author":"R Comtois","year":"1991","unstructured":"R. Comtois, H. Beauregard, M. Somma, O. Serri, N. Aris-Jilwan, J. Hardy, The clinical and endocrine outcome to trans-sphenoidal microsurgery of nonsecreting pituitary adenomas. Cancer 68, 860\u2013866 (1991). https:\/\/doi.org\/10.1002\/1097-0142(19910815)68:4<860::aid-cncr2820680431>3.0.co;2-4","journal-title":"Cancer"},{"key":"2701_CR36","doi-asserted-by":"publisher","first-page":"577","DOI":"10.3171\/jns.1984.61.3.0577","volume":"61","author":"AT Nelson Jr","year":"1984","unstructured":"A.T. Nelson Jr, H.S. Tucker Jr, D.P. Becker, Residual anterior pituitary function following transsphenoidal resection of pituitary macroadenomas. J. Neurosurg. 61, 577\u2013580 (1984). https:\/\/doi.org\/10.3171\/jns.1984.61.3.0577","journal-title":"J. Neurosurg."},{"key":"2701_CR37","doi-asserted-by":"publisher","unstructured":"K. I. Lampropoulos, G. Samonis, P. Nomikos, Factors influencing the outcome of microsurgical transsphenoidal surgery for pituitary adenomas: a study on 184 patients. Hormones 12, 254\u2013264 (2013) https:\/\/doi.org\/10.14310\/horm.2002.1409","DOI":"10.14310\/horm.2002.1409"},{"key":"2701_CR38","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1007\/s11102-020-01045-z","volume":"23","author":"JY Hwang","year":"2020","unstructured":"J.Y. Hwang, D.J. Aum, M.R. Chicoine, R.G. Dacey Jr, J.W. Osbun, K.M. Rich, G.J. Zipfel, C.N. Klatt-Cromwell, J.L. McJunkin, P. Pipkorn, J.S. Schneider, J.M. Silverstein, A.H. Kim, Axis-specific analysis and predictors of endocrine recovery and deficits for non-functioning pituitary adenomas undergoing endoscopic transsphenoidal surgery. Pituitary 23, 389\u2013399 (2020). https:\/\/doi.org\/10.1007\/s11102-020-01045-z","journal-title":"Pituitary"},{"key":"2701_CR39","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1111\/j.1365-2265.2009.03583.x","volume":"71","author":"EP O\u2019Sullivan","year":"2009","unstructured":"E.P. O\u2019Sullivan, C. Woods, N. Glynn, L.A. Behan, R. Crowley, P. O\u2019Kelly, D. Smith, C.J. Thompson, A. Agha, The natural history of surgically treated but radiotherapy-na\u00efve nonfunctioning pituitary adenomas. Clin. Endocrinol. 71, 709\u2013714 (2009). https:\/\/doi.org\/10.1111\/j.1365-2265.2009.03583.x","journal-title":"Clin. Endocrinol."},{"key":"2701_CR40","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1016\/j.wneu.2016.04.059","volume":"91","author":"ER Laws Jr","year":"2016","unstructured":"E.R. Laws Jr, S.L. Iuliano, D.J. Cote, W. Woodmansee, L. Hsu, C.H. Cho, A benchmark for preservation of normal pituitary function after endoscopic transsphenoidal surgery for pituitary macroadenomas. World Neurosurg. 91, 371\u2013375 (2016). https:\/\/doi.org\/10.1016\/j.wneu.2016.04.059","journal-title":"World Neurosurg."},{"key":"2701_CR41","doi-asserted-by":"publisher","first-page":"w13680","DOI":"10.4414\/smw.2012.13680","volume":"142","author":"S Berkmann","year":"2012","unstructured":"S. Berkmann, J. Fandino, B. M\u00fcller, K.F. Kothbauer, C. Henzen, H. Landolt, Pituitary surgery: experience from a large network in Central Switzerland. Swiss Med. Wkly. 142, w13680 (2012). https:\/\/doi.org\/10.4414\/smw.2012.13680","journal-title":"Swiss Med. Wkly."},{"key":"2701_CR42","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1016\/j.wneu.2016.02.059","volume":"89","author":"E Magro","year":"2016","unstructured":"E. Magro, T. Graillon, J. Lassave, F. Castinetti, S. Boissonneau, E. Tabouret, S. Fuentes, L. Velly, R. Gras, H. Dufour, Complications related to the endoscopic endonasal transsphenoidal approach for nonfunctioning pituitary macroadenomas in 300 consecutive patients. World Neurosurg. 89, 442\u2013453 (2016). https:\/\/doi.org\/10.1016\/j.wneu.2016.02.059","journal-title":"World Neurosurg."},{"key":"2701_CR43","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1111\/cen.13365","volume":"87","author":"A Watts","year":"2017","unstructured":"A. Watts, A. Easwaran, P. McNeill, Y.Y. Wang, W. Inder, C. Caputo, Younger age is a risk factor for regrowth and recurrence of nonfunctioning pituitary macroadenomas: Results from a single Australian centre. Clin. Endocrinol. 87, 264\u2013271 (2017). https:\/\/doi.org\/10.1111\/cen.13365. 2017","journal-title":"Clin. Endocrinol."}],"container-title":["Endocrine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12020-021-02701-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12020-021-02701-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12020-021-02701-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,17]],"date-time":"2021-06-17T13:26:42Z","timestamp":1623936402000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12020-021-02701-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,14]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["2701"],"URL":"https:\/\/doi.org\/10.1007\/s12020-021-02701-5","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-163191\/v1","asserted-by":"object"}]},"ISSN":["1355-008X","1559-0100"],"issn-type":[{"value":"1355-008X","type":"print"},{"value":"1559-0100","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,14]]},"assertion":[{"value":"13 January 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 March 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 April 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All authors approve the submission.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The study was approved by the Ethics Committee of the Cliniques Universitaires Saint Luc (UCL) and no informed consent was requested as it was a retrospective study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}