{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T03:37:16Z","timestamp":1783654636560,"version":"3.55.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T00:00:00Z","timestamp":1686096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T00:00:00Z","timestamp":1686096000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Endocrine"],"DOI":"10.1007\/s12020-023-03405-8","type":"journal-article","created":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T06:07:26Z","timestamp":1686118046000},"page":"349-356","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["The recovery time of hypothalamic-pituitary-adrenal axis after curative surgery in Cushing\u2019s disease and its related factor"],"prefix":"10.1007","volume":"81","author":[{"given":"Qiaoli","family":"Cui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quanya","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanwan","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hangping","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoyun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zengyi","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuefei","family":"Shou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiming","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongfei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongying","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7446-0435","authenticated-orcid":false,"given":"Shuo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,6,7]]},"reference":[{"key":"3405_CR1","doi-asserted-by":"publisher","first-page":"2454","DOI":"10.1210\/jc.2007-2734","volume":"93","author":"BM Biller","year":"2008","unstructured":"B.M. Biller, A.B. Grossman, P.M. Stewart et al. Treatment of adrenocorticotropin-dependent Cushing\u2019s syndrome: a consensus statement. J. Clin. Endocrinol. Metab. 93, 2454\u20132462 (2008). https:\/\/doi.org\/10.1210\/jc.2007-2734","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"3405_CR2","doi-asserted-by":"publisher","first-page":"1526","DOI":"10.1210\/jc.2008-0125","volume":"93","author":"LK Nieman","year":"2008","unstructured":"L.K. Nieman, B.M. Biller, J.W. Findling et al. The diagnosis of Cushing\u2019s syndrome: an Endocrine Society Clinical Practice Guideline. J. Clin. Endocrinol. Metab. 93, 1526\u20131540 (2008). https:\/\/doi.org\/10.1210\/jc.2008-0125","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"3405_CR3","doi-asserted-by":"publisher","first-page":"2807","DOI":"10.1210\/jc.2015-1818","volume":"100","author":"LK Nieman","year":"2015","unstructured":"L.K. Nieman, B.M. Biller, J.W. Findling et al. Treatment of Cushing\u2019s syndrome: an endocrine society clinical practice guideline. J Clin. Endocrinol Metab. 100, 2807\u20132831 (2015). https:\/\/doi.org\/10.1210\/jc.2015-1818","journal-title":"J Clin. Endocrinol Metab."},{"key":"3405_CR4","doi-asserted-by":"publisher","unstructured":"R.M. Paragliola, G. Papi, A. Pontecorvi, et al. (2017) Treatment with synthetic glucocorticoids and the hypothalamus-pituitary-adrenal axis. Int J. Mol. Sci. 18, https:\/\/doi.org\/10.3390\/ijms18102201.","DOI":"10.3390\/ijms18102201"},{"key":"3405_CR5","doi-asserted-by":"publisher","first-page":"1300","DOI":"10.1210\/jc.2014-3632","volume":"100","author":"CM Berr","year":"2015","unstructured":"C.M. Berr, G. Di Dalmazi, A. Osswald et al. Time to recovery of adrenal function after curative surgery for Cushing\u2019s syndrome depends on etiology. J. Clin. Endocrinol. Metab. 100, 1300\u20131308 (2015). https:\/\/doi.org\/10.1210\/jc.2014-3632","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"3405_CR6","doi-asserted-by":"publisher","first-page":"717","DOI":"10.4158\/ep11013.Or","volume":"17","author":"MI Khan","year":"2011","unstructured":"M.I. Khan, M.A. Habra, I.E. McCutcheon et al. Random postoperative day-3 cortisol concentration as a predictor of hypothalamic-pituitary-adrenal axis integrity after transsphenoidal surgery. Endocrine Pract. 17, 717\u2013726 (2011). https:\/\/doi.org\/10.4158\/ep11013.Or","journal-title":"Endocrine Pract."},{"key":"3405_CR7","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1159\/000496846","volume":"108","author":"AL Serban","year":"2019","unstructured":"A.L. Serban, E. Sala, G. Carosi et al. Recovery of adrenal function after pituitary surgery in patients with cushing disease: persistent remission or recurrence? Neuroendocrinology 108, 211\u2013218 (2019). https:\/\/doi.org\/10.1159\/000496846","journal-title":"Neuroendocrinology"},{"key":"3405_CR8","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1016\/s2213-8587(21)00235-7","volume":"9","author":"M Fleseriu","year":"2021","unstructured":"M. Fleseriu, R. Auchus, I. Bancos et al. Consensus on diagnosis and management of Cushing\u2019s disease: a guideline update. Lancet Diabetes Endocrinol. 9, 847\u2013875 (2021). https:\/\/doi.org\/10.1016\/s2213-8587(21)00235-7","journal-title":"Lancet Diabetes Endocrinol."},{"key":"3405_CR9","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1007\/s12020-021-02848-1","volume":"75","author":"C Dai","year":"2022","unstructured":"C. Dai, M. Feng, B. Sun et al. Surgical outcome of transsphenoidal surgery in Cushing\u2019s disease: a case series of 1106 patients from a single center over 30 years. Endocrine 75, 219\u2013227 (2022). https:\/\/doi.org\/10.1007\/s12020-021-02848-1","journal-title":"Endocrine"},{"key":"3405_CR10","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1210\/jc.2009-1672","volume":"95","author":"E Valassi","year":"2010","unstructured":"E. Valassi, B.M. Biller, B. Swearingen et al. Delayed remission after transsphenoidal surgery in patients with Cushing\u2019s disease. J Clin. Endocrinol Metab. 95, 601\u2013610 (2010). https:\/\/doi.org\/10.1210\/jc.2009-1672","journal-title":"J Clin. Endocrinol Metab."},{"key":"3405_CR11","doi-asserted-by":"publisher","unstructured":"X. He, J. Findling, R.J.P. Auchus, (2022) Glucocorticoid withdrawal syndrome following treatment of endogenous Cushing Syndrome. https:\/\/doi.org\/10.1007\/s11102-022-01218-y.","DOI":"10.1007\/s11102-022-01218-y"},{"key":"3405_CR12","doi-asserted-by":"publisher","first-page":"bvac010","DOI":"10.1210\/jendso\/bvac010","volume":"6","author":"EV Varlamov","year":"2022","unstructured":"E.V. Varlamov, G. Vila, M. Fleseriu, Perioperative management of a patient with cushing disease. J. Endocrine Soc. 6, bvac010 (2022). https:\/\/doi.org\/10.1210\/jendso\/bvac010","journal-title":"J. Endocrine Soc"},{"key":"3405_CR13","doi-asserted-by":"publisher","first-page":"4586229","DOI":"10.1155\/2021\/4586229","volume":"2021","author":"Q Cui","year":"2021","unstructured":"Q. Cui, D. Liu, B. Xiang et al. Morning serum cortisol as a predictor for the HPA axis recovery in cushing\u2019s disease. Int. J. Endocrinol. 2021, 4586229 (2021). https:\/\/doi.org\/10.1155\/2021\/4586229","journal-title":"Int. J. Endocrinol."},{"key":"3405_CR14","doi-asserted-by":"publisher","first-page":"3888","DOI":"10.1210\/jc.2016-2118","volume":"101","author":"M Fleseriu","year":"2016","unstructured":"M. Fleseriu, I.A. Hashim, N. Karavitaki et al. Hormonal replacement in hypopituitarism in adults: an endocrine society clinical practice guideline. J. Clin. Endocrinol. Metab. 101, 3888\u20133921 (2016). https:\/\/doi.org\/10.1210\/jc.2016-2118","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"3405_CR15","first-page":"835","volume":"96","author":"CPAS Council","year":"2015","unstructured":"C.P.A.S. Council, Consensus of Chinese experts on diagnosis and treatment of Cushing\u2019s disease. Natl. Med. J. China 96, 835\u2013840 (2015)","journal-title":"Natl. Med. J. China"},{"key":"3405_CR16","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1111\/cen.14300","volume":"94","author":"C Tatsi","year":"2021","unstructured":"C. Tatsi, M. Neely, C. Flippo et al. Recovery of hypothalamic-pituitary-adrenal axis in paediatric Cushing disease. Clin. Endocrinol. 94, 40\u201347 (2021). https:\/\/doi.org\/10.1111\/cen.14300","journal-title":"Clin. Endocrinol."},{"key":"3405_CR17","doi-asserted-by":"publisher","first-page":"1483","DOI":"10.1210\/jc.2011-2325","volume":"97","author":"M Lodish","year":"2012","unstructured":"M. Lodish, S.V. Dunn, N. Sinaii et al. Recovery of the hypothalamic-pituitary-adrenal axis in children and adolescents after surgical cure of Cushing\u2019s disease. J. Clin. Endocrinol. Metab. 97, 1483\u20131491 (2012). https:\/\/doi.org\/10.1210\/jc.2011-2325","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"3405_CR18","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1111\/j.1365-2265.2004.02111.x","volume":"61","author":"M Klose","year":"2004","unstructured":"M. Klose, K. J\u00f8rgensen, L. Kristensen, Characteristics of recovery of adrenocortical function after treatment for Cushing\u2019s syndrome due to pituitary or adrenal adenomas. Clin. Endocrinol. 61, 394\u2013399 (2004). https:\/\/doi.org\/10.1111\/j.1365-2265.2004.02111.x","journal-title":"Clin. Endocrinol."},{"key":"3405_CR19","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1210\/jcem-43-2-338","volume":"43","author":"RN Re","year":"1976","unstructured":"R.N. Re, I.A. Kourides, E.C. Ridgway et al. The effect of glucocorticoid administration on human pituitary secretion of thyrotropin and prolactin. J. Clin. Endocrinol. Metab. 43, 338\u2013346 (1976). https:\/\/doi.org\/10.1210\/jcem-43-2-338","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"3405_CR20","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1530\/acta.0.0960480","volume":"96","author":"TJ Visser","year":"1981","unstructured":"T.J. Visser, S.W. Lamberts, Regulation of TSH secretion and thyroid function in Cushing\u2019s disease. Acta endocrinologica 96, 480\u2013483 (1981). https:\/\/doi.org\/10.1530\/acta.0.0960480","journal-title":"Acta endocrinologica"},{"key":"3405_CR21","doi-asserted-by":"publisher","unstructured":"R.M. Paragliola, A. Corsello, G. Papi, et al. (2021) Cushing\u2019s syndrome effects on the thyroid. Int. J. Mol. Sci. 22, https:\/\/doi.org\/10.3390\/ijms22063131.","DOI":"10.3390\/ijms22063131"},{"key":"3405_CR22","doi-asserted-by":"publisher","first-page":"e1316","DOI":"10.1210\/clinem\/dgaa858","volume":"106","author":"S Shekhar","year":"2021","unstructured":"S. Shekhar, R. McGlotten, S. Auh et al. The hypothalamic-pituitary-thyroid axis in cushing syndrome before and after curative surgery. J. Clin. Endocrinol. Metab. 106, e1316\u2013e1331 (2021). https:\/\/doi.org\/10.1210\/clinem\/dgaa858","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"3405_CR23","doi-asserted-by":"publisher","first-page":"1176","DOI":"10.1530\/ec-19-0309","volume":"8","author":"B Xiang","year":"2019","unstructured":"B. Xiang, R. Tao, X. Liu et al. A study of thyroid functions in patients with Cushing\u2019s syndrome: a single-center experience. Endocrine Connections 8, 1176\u20131185 (2019). https:\/\/doi.org\/10.1530\/ec-19-0309","journal-title":"Endocrine Connections"},{"key":"3405_CR24","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1007\/s12020-022-03083-y","volume":"77","author":"H Zheng","year":"2022","unstructured":"H. Zheng, Q. Wang, Q. Cui et al. The hypothalamic-pituitary-gonad axis in male Cushing\u2019s disease before and after curative surgery. Endocrine 77, 357\u2013362 (2022). https:\/\/doi.org\/10.1007\/s12020-022-03083-y","journal-title":"Endocrine"},{"key":"3405_CR25","doi-asserted-by":"publisher","first-page":"850328","DOI":"10.3389\/fendo.2022.850328","volume":"13","author":"S Sciacchitano","year":"2022","unstructured":"S. Sciacchitano, C. Capalbo, C. Napoli et al. Nonthyroidal illness syndrome: to treat or not to treat? have we answered the question? a review of metanalyses. Front. Endocrinol. 13, 850328 (2022). https:\/\/doi.org\/10.3389\/fendo.2022.850328","journal-title":"Front. Endocrinol."}],"container-title":["Endocrine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12020-023-03405-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12020-023-03405-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12020-023-03405-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T08:16:39Z","timestamp":1687767399000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12020-023-03405-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,7]]},"references-count":25,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,8]]}},"alternative-id":["3405"],"URL":"https:\/\/doi.org\/10.1007\/s12020-023-03405-8","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-2234151\/v1","asserted-by":"object"}]},"ISSN":["1559-0100"],"issn-type":[{"value":"1559-0100","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,7]]},"assertion":[{"value":"3 November 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 May 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 June 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}