{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T15:15:57Z","timestamp":1784560557760,"version":"3.55.0"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T00:00:00Z","timestamp":1734566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T00:00:00Z","timestamp":1734566400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Endocrine"],"DOI":"10.1007\/s12020-024-04141-3","type":"journal-article","created":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T21:07:25Z","timestamp":1734642445000},"page":"295-303","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Characteristics of lipid metabolism and fat distribution in patients with primary hyperparathyroidism and their Mendelian randomization study"],"prefix":"10.1007","volume":"88","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2650-5499","authenticated-orcid":false,"given":"Ying","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinqiong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1217-1387","authenticated-orcid":false,"given":"Qin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,12,19]]},"reference":[{"key":"4141_CR1","first-page":"N18","volume":"17","author":"S Adami","year":"2002","unstructured":"S. Adami, C. Marcocci, D. Gatti, Epidemiology of primary hyperparathyroidism in Europe. J. Bone Min. Res 17, N18\u2013N23 (2002).","journal-title":"J. Bone Min. Res"},{"key":"4141_CR2","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/S0008-6363(97)00194-6","volume":"37","author":"KD Schluter","year":"1998","unstructured":"K.D. Schluter, H.M. Piper, Cardiovascular actions of parathyroid hormone and parathyroid hormone-related peptide. Cardiovasc. Res. 37, 34\u201341 (1998)","journal-title":"Cardiovasc. Res."},{"key":"4141_CR3","doi-asserted-by":"crossref","first-page":"745","DOI":"10.7326\/0003-4819-121-10-199411150-00003","volume":"121","author":"AB Grey","year":"1994","unstructured":"A.B. Grey, M.C. Evans, J.P. Stapleton, I.R. Reid, Body weight and bone mineral density in postmenopausal women with primary hyperparathyroidism. Ann. Intern. Med. 121, 745\u2013749 (1994)","journal-title":"Ann. Intern. Med."},{"key":"4141_CR4","doi-asserted-by":"crossref","unstructured":"A. Grey, I. Reid Body weight and bone mineral density in hyperparathyroidism. Ann. Intern. Med. 123, 732 (1995)","DOI":"10.7326\/0003-4819-123-9-199511010-00021"},{"key":"4141_CR5","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.bone.2005.08.018","volume":"38","author":"MJ Bolland","year":"2006","unstructured":"M.J. Bolland, A.B. Grey, R.W. Ames, A.M. Horne, G.D. Gamble, I.R. Reid, Fat mass is an important predictor of parathyroid hormone levels in postmenopausal women. Bone 38, 317\u2013321 (2006)","journal-title":"Bone"},{"key":"4141_CR6","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1038\/bonekey.2016.85","volume":"5","author":"EO Billington","year":"2016","unstructured":"E.O. Billington, G.D. Gamble, I.R. Reid, Parathyroid hormone reflects adiposity and cardiometabolic indices but not bone density in normal men. BoneKEy Rep. 5, 852 (2016)","journal-title":"BoneKEy Rep."},{"key":"4141_CR7","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1111\/j.1365-2265.2009.03558.x","volume":"71","author":"T Ahlstr\u00f6m","year":"2009","unstructured":"T. Ahlstr\u00f6m, E. Hagstr\u00f6m, A. Larsson, C. Rudberg, L. Lind, P. Hellman, Correlation between plasma calcium, parathyroid hormone (PTH) and the metabolic syndrome (MetS) in a community based cohort of men and women. Clin. Endocrinol. 71, 673\u2013678 (2009)","journal-title":"Clin. Endocrinol."},{"key":"4141_CR8","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1210\/jc.2004-1891","volume":"90","author":"MJ Bolland","year":"2005","unstructured":"M.J. Bolland, A.B. Grey, G.D. Gamble, I.R. Reid, Association between primary hyperparathyroidism and increased body weight: a meta-analysis. J. Clin. Endocrinol. Metab. 90, 1525\u20131530 (2005)","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"4141_CR9","doi-asserted-by":"crossref","first-page":"2132","DOI":"10.1002\/jbmr.3554","volume":"33","author":"C Cipriani","year":"2018","unstructured":"C. Cipriani, J. Pepe, B.C. Silva, M.R. Rubin, N.E. Cusano, D.J. McMahon, L. Nieddu, M. Angelozzi, F. Biamonte, D. Diacinti, D. Hans, S. Minisola, J.P. Bilezikian, Comparative effect of rhPTH (1-84) on bone mineral density and trabecular bone score in hypoparathyroidism and postmenopausal osteoporosis. J. Bone Min. Res. 33, 2132\u20132139 (2018)","journal-title":"J. Bone Min. Res."},{"issue":"2","key":"4141_CR10","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.cmet.2015.11.003","volume":"23","author":"S Kir","year":"2016","unstructured":"S. Kir, H. Komaba, A.P. Garcia, K.P. Economopoulos, W. Liu, B. Lanske, R.A. Hodin, B.M. Spiegelman, PTH\/PTHrP receptor mediates cachexia in models of kidney failure and cancer. Cell Metab. 23(2), 315\u2013323 (2016).","journal-title":"Cell Metab."},{"key":"4141_CR11","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.ebiom.2018.11.057","volume":"40","author":"Y He","year":"2019","unstructured":"Y. He et al. The browning of white adipose tissue and body weight loss in primary hyperparathyroidism. eBioMedicine 40, 56\u201366 (2019)","journal-title":"eBioMedicine"},{"issue":"3","key":"4141_CR12","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1007\/s12020-021-02635-y","volume":"72","author":"TJ Yuan","year":"2021","unstructured":"T.J. Yuan, L.P. Chen, Y.L. Pan et al. An inverted U-shaped relationship between parathyroid hormone and body weight, body mass index, body fat. Endocrine 72(3), 844\u2013851 (2021)","journal-title":"Endocrine"},{"key":"4141_CR13","volume":"9","author":"Y Tang","year":"2022","unstructured":"Y. Tang, J. Wu, M. Xu et al. Causal associations of iron status and back pain risk: a Mendelian randomization study. Front Nutr. 9, 923590 (2022)","journal-title":"Front Nutr."},{"key":"4141_CR14","volume":"14","author":"Y Jiang","year":"2023","unstructured":"Y. Jiang, R. Chen, S. Xu et al. Assessing causal associations of hyperparathyroidism with blood counts and biochemical indicators: a Mendelian randomization study. Front Endocrinol. 14, 1295040 (2023)","journal-title":"Front Endocrinol."},{"key":"4141_CR15","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1056\/NEJMoa2102953","volume":"385","author":"LA Inker","year":"2021","unstructured":"L.A. Inker, N.D. Eneanya, J. Coresh, H. Tighiouart, D. Wang, Y. Sang et al. Chronic kidney disease epidemiology collaboration.new creatinine- and cystatin C-based equations to estimate GFR without race. N. Engl. J. Med. 385, 1737\u20131749 (2021)","journal-title":"N. Engl. J. Med."},{"issue":"9596","key":"4141_CR16","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/S0140-6736(07)61602-X","volume":"370","author":"E von Elm","year":"2007","unstructured":"E. von Elm, D.G. Altman, M. Egger et al. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Lancet 370(9596), 1453\u20131457 (2007)","journal-title":"Lancet"},{"issue":"3","key":"4141_CR17","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1093\/ije\/dyw127","volume":"45","author":"DA Lawlor","year":"2016","unstructured":"D.A. Lawlor, Commentary: two-sample Mendelian randomization: opportunities and challenges. Int. J. Epidemiol. 45(3), 908\u2013915 (2016)","journal-title":"Int. J. Epidemiol."},{"issue":"3","key":"4141_CR18","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1093\/ije\/dyr036","volume":"40","author":"S Burgess","year":"2011","unstructured":"S. Burgess, S.G. Thompson, Avoiding bias from weak instruments in Mendelian randomization studies. Int. J. Epidemiol. 40(3), 755\u2013764 (2011)","journal-title":"Int. J. Epidemiol."},{"issue":"1","key":"4141_CR19","doi-asserted-by":"crossref","DOI":"10.1186\/s12916-021-02152-9","volume":"19","author":"S Park","year":"2021","unstructured":"S. Park, S. Lee, Y. Kim et al. Causal effects of atrial fibrillation on brain white and gray matter volume: a Mendelian randomization study. BMC Med. 19(1), 274 (2021).","journal-title":"BMC Med."},{"issue":"5","key":"4141_CR20","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s10654-017-0255-x","volume":"32","author":"S Burgess","year":"2017","unstructured":"S. Burgess, S.G. Thompson, Interpreting findings from Mendelian randomization using the MR-Egger method. Eur. J. Epidemiol. 32(5), 377\u2013389 (2017)","journal-title":"Eur. J. Epidemiol."},{"key":"4141_CR21","doi-asserted-by":"crossref","first-page":"851","DOI":"10.2147\/DMSO.S245096","volume":"13","author":"XJ Jia","year":"2020","unstructured":"X.J. Jia, L.-X. Liu, R. Wang et al. Relationship of two-hour plasma glucose and abdominal visceral fat with bone mineral density and bone mineral content in women with different Glucose metabolism status[J]. Diab. Metab. Syndr. Obes. 13, 851\u2013858 (2020)","journal-title":"Diab. Metab. Syndr. Obes."}],"container-title":["Endocrine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12020-024-04141-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12020-024-04141-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12020-024-04141-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T07:55:59Z","timestamp":1742802959000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12020-024-04141-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,19]]},"references-count":21,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,4]]}},"alternative-id":["4141"],"URL":"https:\/\/doi.org\/10.1007\/s12020-024-04141-3","relation":{},"ISSN":["1559-0100"],"issn-type":[{"value":"1559-0100","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,19]]},"assertion":[{"value":"24 August 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 December 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Studies involving human participants were reviewed and approved by the Medical Ethics Committee of West China Hospital of Sichuan University. For this type of study, formal consent is not needed.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics"}}]}}