{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:01:24Z","timestamp":1791975684847,"version":"4.4.0"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T00:00:00Z","timestamp":1744156800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T00:00:00Z","timestamp":1744156800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Endocrine"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Purpose<\/jats:title>\n            <jats:p>Postoperative hypoparathyroidism is the most common complication after total thyroidectomy(TT). The clinical significance of incidental parathyroid glands(IP) detected in pathological examination of removed surgical material is still controversial. The aim of this study was to evaluate the clinical follow-up findings and risk factors of patients with IP.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>Postoperative pathology results and postoperative biochemical findings of patients who underwent TT\u00b1Central Neck Dissection(CND)\/Lateral Neck Dissection(LND) between September,2020 and September,2023 in single institution were retrospectively evaluated. Patients with IP were divided into Group-1, and patients without IP were divided into Group-2. Patients of Group-1 were divided as Single IP and Double IP subgroups according to the number of IP.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>The findings of a total of 412 patients were evaluated. IP was detected in 90(21.8%) of the patients. Postoperative hypoparathyroidism was more common in Group-1 at the 6th\u2009hour, 24th\u2009hour and 1st month postoperatively (69.7% vs. 31.7%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001; 61.1% vs. 27.7%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001, 26.2% vs. 12.2%, <jats:italic>p<\/jats:italic>\u2009=\u20090.002, respectively). Persistent hypoparathyroidism was observed at a rate of 5.3% in Group-2 and 11.5% in Group-1 (<jats:italic>p<\/jats:italic>\u2009=\u20090.041). Postoperative hypocalcemia was seen more frequently in Group-1 than in Group-2 at the 12th hour (34.4% vs. 23.2%, <jats:italic>p<\/jats:italic>\u2009=\u20090.031, respectively). There was no difference between Single IP vs. Double IP groups for the serum levels of Calcium and PTH. Among the risk factors evaluated for the detection of IP, in the univariance analysis, operation indications(<jats:italic>p<\/jats:italic>\u2009=\u20090.018), CND(<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001), surgeon experience(<jats:italic>p<\/jats:italic>\u2009=\u20090.016), thyroid gland volume(<jats:italic>p<\/jats:italic>\u2009=\u20090.02), preoperative serum TSH value(<jats:italic>p<\/jats:italic>\u2009=\u20090.031); in multivariance analysis, operation type (\u2009\u00b1\u2009CND) (OR:2.785; 95% CI: 1.175\u20136.605; <jats:italic>p<\/jats:italic>\u2009=\u20090.020) and operator experience between 10\u201320 years (OR: 0.117, 95% CI: 0.033\u20130.418, <jats:italic>p<\/jats:italic>\u2009=\u20090.001) and &gt;20 years (OR: 0.254, 95%CI: 0.085\u20130.760, <jats:italic>p<\/jats:italic>\u2009=\u20090.014) were found significant compared to operators experienced &lt;5 years.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Patients with detected IP after total thyroidectomy have lower postoperative Calcium and PTH. Significant risk factors for the IP were low level of surgeon experience and undergoing CND.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s12020-025-04225-8","type":"journal-article","created":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T20:37:36Z","timestamp":1744231056000},"page":"240-249","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Clinical significance and risk factors of incidental parathyroidectomy after total thyroidectomy"],"prefix":"10.1007","volume":"89","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7259-2461","authenticated-orcid":false,"given":"Mehmet","family":"Kostek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2306-8756","authenticated-orcid":false,"given":"Isik","family":"Cetinoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3147-1688","authenticated-orcid":false,"given":"Zerin","family":"Sengul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2662-5264","authenticated-orcid":false,"given":"Hazal","family":"Arikan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3487-609X","authenticated-orcid":false,"given":"Mehmet Taner","family":"Unlu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0408-2392","authenticated-orcid":false,"given":"Ozan","family":"Caliskan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7353-8245","authenticated-orcid":false,"given":"Nurcihan","family":"Aygun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1826-1615","authenticated-orcid":false,"given":"Mehmet","family":"Uludag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,9]]},"reference":[{"key":"4225_CR1","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1186\/s12893-023-02176-3","volume":"23","author":"C Melot","year":"2023","unstructured":"C. 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Material preparation, data collection and analysis were performed by Mehmet Kostek, Isik Cetinoglu, Zerin Sengul and Hazal Arikan. The first draft of the manuscript was written by Mehmet Kostek and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript. This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Local Ethics Committee of University of Health Sciences Sisli Hamidiye Etfal Training and Research Hospital (Date: 25.06.2024, Number: 4450).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and informed consent"}}]}}