{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T19:13:34Z","timestamp":1757618014772,"version":"3.44.0"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T00:00:00Z","timestamp":1747094400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T00:00:00Z","timestamp":1747094400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Endocrine"],"DOI":"10.1007\/s12020-025-04264-1","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T13:21:53Z","timestamp":1747142513000},"page":"627-631","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Familial complete androgen insensitivity syndrome (CAIS): a case series of three siblings with emphasis on diagnosis, management, and psychosocial outcomes"],"prefix":"10.1007","volume":"89","author":[{"given":"Vaishnavi","family":"Rajaraman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Usha","family":"Vishwanath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence","family":"D. Cruze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,5,13]]},"reference":[{"key":"4264_CR1","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.3390\/ijms22031264","volume":"22","author":"N Tyutyusheva","year":"2021","unstructured":"N. Tyutyusheva, I. Mancini, G.I. Baroncelli, S. D\u2019Elios, D. Peroni, M.C. Meriggiola et al., Complete androgen insensitivity syndrome: from bench to bed. Int. J. Mol. Sci. 22, 1264 (2021).","journal-title":"Int. J. Mol. Sci."},{"key":"4264_CR2","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1016\/j.ijscr.2020.01.032","volume":"71","author":"S Fulare","year":"2020","unstructured":"S. Fulare, S. Deshmukh, J. Gupta, Androgen Insensitivity syndrome: a rare genetic disorder. Int. J. Surg. Case Rep. 71, 371\u2013373 (2020).","journal-title":"Int. J. Surg. Case Rep."},{"key":"4264_CR3","doi-asserted-by":"publisher","first-page":"4532","DOI":"10.1210\/jc.2016-2248","volume":"101","author":"A Berglund","year":"2016","unstructured":"A. Berglund, T.H. Johannsen, K. Stochholm, M.H. Viuff, J. Fedder, K.M. Main et al., Incidence, prevalence, diagnostic delay, and clinical presentation of female 46,XY disorders of sex development. J. Clin. Endocrinol. Metab. 101, 4532\u20134540 (2016).","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"4264_CR4","doi-asserted-by":"publisher","first-page":"54","DOI":"10.5582\/irdr.2014.01035","volume":"4","author":"J Shao","year":"2015","unstructured":"J. Shao, J. Hou, B. Li, D. Li, N. Zhang, X. Wang, Different types of androgen receptor mutations in patients with complete androgen insensitivity syndrome. Intractable Rare Dis. Res. 4, 54\u201359 (2015).","journal-title":"Intractable Rare Dis. Res."},{"key":"4264_CR5","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1038\/nrendo.2015.69","volume":"11","author":"JC Achermann","year":"2015","unstructured":"J.C. Achermann, S. Domenice, T.A. Bachega, M.Y. Nishi, B.B. Mendonca, Disorders of sex development: effect of molecular diagnostics. Nat. Rev. Endocrinol. 11, 478\u2013488 (2015).","journal-title":"Nat. Rev. Endocrinol."},{"key":"4264_CR6","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/j.cca.2022.03.021","volume":"531","author":"D Zhou","year":"2022","unstructured":"D. Zhou, H. Xu, X. Shen, R. Gu, Y. Chen, G. Chen et al., Complete androgen insensitivity syndrome caused by a novel mutation in the androgen receptor gene and its mechanism. Clin. Chim. Acta 531, 94\u201399 (2022).","journal-title":"Clin. Chim. Acta"},{"key":"4264_CR7","doi-asserted-by":"publisher","first-page":"227","DOI":"10.20945\/2359-3997000000031","volume":"62","author":"RL Batista","year":"2018","unstructured":"R.L. Batista, E.M.F. Costa, A. Rodrigues, S. de, N.L. Gomes, J.A. Faria Jr, M.Y. Nishi et al., Androgen insensitivity syndrome: a review. Arch. Endocrinol. Metab. 62, 227\u2013235 (2018).","journal-title":"Arch. Endocrinol. Metab."},{"key":"4264_CR8","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1037\/sgd0000081","volume":"2","author":"RJ Testa","year":"2015","unstructured":"R.J. Testa, J. Habarth, J. Peta, K. Balsam, W. Bockting, Development of the gender minority stress and resilience measure. Psychol. Sex. Orientat. Gend. Divers. 2, 65\u201377 (2015).","journal-title":"Psychol. Sex. Orientat. Gend. Divers."},{"key":"4264_CR9","doi-asserted-by":"publisher","first-page":"19","DOI":"10.6065\/apem.2040170.085","volume":"26","author":"BA Barros","year":"2021","unstructured":"B.A. Barros, L.R. Oliveira, C.R.C. de, Surur, A. Barros-Filho, A.T. Maciel-Guerra, G. Guerra-Junior, Complete androgen insensitivity syndrome and risk of gonadal malignancy: systematic review. Ann. Pediatr. Endocrinol. Metab. 26, 19\u201323 (2021).","journal-title":"Ann. Pediatr. Endocrinol. Metab."},{"key":"4264_CR10","doi-asserted-by":"publisher","DOI":"10.1016\/j.gpeds.2023.100079","volume":"6","author":"A Vatopoulou","year":"2023","unstructured":"A. Vatopoulou, T. Kanavos, F. Gkrozou, E. Birbas, O. Tsonis, C. Skentou et al., Complete androgen insensitivity syndrome in two sisters: physical and psychological results after different approach of neovagina formation. Glob. Pediatr. 6, 100079 (2023).","journal-title":"Glob. Pediatr."}],"container-title":["Endocrine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12020-025-04264-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12020-025-04264-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12020-025-04264-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T15:01:31Z","timestamp":1757170891000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12020-025-04264-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,13]]},"references-count":10,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,8]]}},"alternative-id":["4264"],"URL":"https:\/\/doi.org\/10.1007\/s12020-025-04264-1","relation":{},"ISSN":["1559-0100"],"issn-type":[{"type":"electronic","value":"1559-0100"}],"subject":[],"published":{"date-parts":[[2025,5,13]]},"assertion":[{"value":"9 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 April 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 May 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Approval for the study was obtained from the institutional ethics committee, ensuring adherence to ethical guidelines and standards. All procedures were conducted in compliance with institutional regulations to maintain the integrity and ethical conduct of the research process.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Written informed consent was obtained from the patient for academic purposes, including permission to publish the provided images. Care was taken to ensure that the patient\u2019s face and personal identity remain undisclosed, maintaining confidentiality and adhering to ethical standards for the use of patient data in academic publications.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}