{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T19:38:11Z","timestamp":1790797091535,"version":"4.1.0"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T00:00:00Z","timestamp":1758326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T00:00:00Z","timestamp":1758326400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Noncommunicable Chronic Diseases-National Science and Technology Major Project","award":["2023ZD0506800"],"award-info":[{"award-number":["2023ZD0506800"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81800692"],"award-info":[{"award-number":["81800692"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Endocrine"],"DOI":"10.1007\/s12020-025-04433-2","type":"journal-article","created":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T07:20:32Z","timestamp":1758352832000},"page":"1438-1445","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Follow-up of hypogonadotropic hypogonadism recovery in Chinese male prolactinoma patients treated with dopamine agonists"],"prefix":"10.1007","volume":"90","author":[{"given":"Yuanpin","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujia","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiaoli","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hangping","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanwan","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lili","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoming","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiming","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongying","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxia","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijin","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,9,20]]},"reference":[{"issue":"12","key":"4433_CR1","doi-asserted-by":"publisher","first-page":"722","DOI":"10.1038\/s41574-023-00886-5","volume":"19","author":"S Petersenn","year":"2023","unstructured":"S. Petersenn, M. Fleseriu, F.F. Casanueva, A. Giustina, N. Biermasz, B.M.K. Biller et al., Diagnosis and management of prolactin-secreting pituitary adenomas: a pituitary society international consensus statement. Nat. Rev. Endocrinol. 19(12), 722\u2013740 (2023)","journal-title":"Nat. Rev. Endocrinol."},{"issue":"2","key":"4433_CR2","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1001\/jama.2020.3744","volume":"325","author":"PP Huynh","year":"2021","unstructured":"P.P. Huynh, L.E. Ishii, M. Ishii, Prolactinomas JAMA 325(2), 195 (2021)","journal-title":"Prolactinomas JAMA"},{"issue":"3","key":"4433_CR3","doi-asserted-by":"publisher","first-page":"P1","DOI":"10.1530\/EJE-21-0977","volume":"186","author":"R Cozzi","year":"2022","unstructured":"R. Cozzi, M.R. Ambrosio, R. Attanasio, C. Battista, A. Bozzao, M. Caputo et al., Italian association of clinical endocrinologists (AME) and international chapter of clinical endocrinology (ICCE). Position statement for clinical practice: prolactin-secreting tumors. Eur. J. Endocrinol. 186(3), P1\u2013P33 (2022)","journal-title":"Eur. J. Endocrinol."},{"key":"4433_CR4","doi-asserted-by":"publisher","first-page":"1338345","DOI":"10.3389\/fendo.2024.1338345","volume":"15","author":"L Dzialach","year":"2024","unstructured":"L. Dzialach, J. Sobolewska, Z. Zak, W. Respondek, P. Witek, Prolactin-secreting pituitary adenomas: male-specific differences in pathogenesis, clinical presentation and treatment. Front. Endocrinol. (Lausanne). 15, 1338345 (2024)","journal-title":"Front. Endocrinol. (Lausanne)"},{"key":"4433_CR5","doi-asserted-by":"crossref","unstructured":"H. Duskin-Bitan, I. Shimon, Prolactinomas in males: any differences? Pituitary 2020, 23(1): 52\u201357","DOI":"10.1007\/s11102-019-01009-y"},{"issue":"7","key":"4433_CR6","doi-asserted-by":"publisher","first-page":"1398","DOI":"10.1111\/andr.13428","volume":"11","author":"Y Rudman","year":"2023","unstructured":"Y. Rudman, H. Duskin-Bitan, I. Richter, G. Tsvetov, H. Masri-Iraqi, A. Akirov et al., Hemoglobin decline as a signal for hyperprolactinemia onset prior to prolactinoma diagnosis in hypogonadal men. Andrology. 11(7), 1398\u20131407 (2023)","journal-title":"Andrology"},{"issue":"10444","key":"4433_CR7","doi-asserted-by":"publisher","first-page":"2632","DOI":"10.1016\/S0140-6736(24)00342-8","volume":"403","author":"M Fleseriu","year":"2024","unstructured":"M. Fleseriu, M. Christ-Crain, F. Langlois, M. Gadelha, S. Melmed, Hypopituitarism Lancet. 403(10444), 2632\u20132648 (2024)","journal-title":"Hypopituitarism Lancet"},{"issue":"5","key":"4433_CR8","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1007\/s11102-024-01445-5","volume":"27","author":"SM Constantinescu","year":"2024","unstructured":"S.M. Constantinescu, D. Maiter, O. Alexopoulou, Recovery from hypogonadism in men with prolactinoma treated with dopamine agonists. Pituitary. 27(5), 625\u2013634 (2024)","journal-title":"Pituitary"},{"issue":"4","key":"4433_CR9","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1007\/s11102-022-01242-y","volume":"25","author":"KM Al Dahmani","year":"2022","unstructured":"K.M. Al Dahmani, M.H. Almalki, A. Ekhzaimy, F. Aziz, A. Bashier, M.M. Mahzari et al., Proportion and predictors of hypogonadism recovery in men with macroprolactinomas treated with dopamine agonists. Pituitary. 25(4), 658\u2013666 (2022)","journal-title":"Pituitary"},{"key":"4433_CR10","doi-asserted-by":"crossref","unstructured":"M. Sehemby, A.R. Lila, V. Sarathi, R. Shah, S. Sankhe, S.K. Jaiswal et al., Predictors of chronic LH-Testosterone axis suppression in male macroprolactinomas with normoprolactinemia on Cabergoline. J. Clin. Endocrinol. Metab. 2020, 105(12)","DOI":"10.1210\/clinem\/dgaa650"},{"issue":"1","key":"4433_CR11","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1007\/s11102-014-0563-z","volume":"18","author":"A Tirosh","year":"2015","unstructured":"A. Tirosh, C. Benbassat, A. Lifshitz, I. Shimon, Hypopituitarism patterns and prevalence among men with macroprolactinomas. Pituitary. 18(1), 108\u2013115 (2015)","journal-title":"Pituitary"},{"issue":"1","key":"4433_CR12","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1007\/s12020-025-04215-w","volume":"89","author":"Y Rudman","year":"2025","unstructured":"Y. Rudman, N. Simon, R. Shimon, G. Drozdinsky, E. Markus, H. Duskin-Bitan et al., Response to Cabergoline treatment, gonadal axis recovery, and outcomes of drug withdrawal, in men with microprolactinoma: a retrospective cohort study. Endocrine. 89(1), 212\u2013221 (2025)","journal-title":"Endocrine"},{"issue":"6","key":"4433_CR13","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1007\/s11102-022-01259-3","volume":"25","author":"Y Rudman","year":"2022","unstructured":"Y. Rudman, H. Duskin-Bitan, H. Masri-Iraqi, A. Akirov, I. Shimon, Predicting hypogonadotropic hypogonadism persistence in male macroprolactinoma. Pituitary. 25(6), 882\u2013890 (2022)","journal-title":"Pituitary"},{"issue":"11","key":"4433_CR14","doi-asserted-by":"publisher","first-page":"3888","DOI":"10.1210\/jc.2016-2118","volume":"101","author":"M Fleseriu","year":"2016","unstructured":"M. Fleseriu, I.A. Hashim, N. Karavitaki, S. Melmed, M.H. Murad, R. Salvatori et al., Hormonal replacement in hypopituitarism in adults: an endocrine society clinical practice guideline. J. Clin. Endocrinol. Metab. 101(11), 3888\u20133921 (2016)","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"8","key":"4433_CR15","doi-asserted-by":"publisher","first-page":"103102","DOI":"10.1016\/j.arcmed.2024.103102","volume":"55","author":"F Haidenberg-David","year":"2024","unstructured":"F. Haidenberg-David, J. Sidauy-Adissi, A. Moscona-Nissan, E. Jonguitud-Zumaya, M. Fugarolas-Morinelli, F. Martinez-Mendoza et al., Overview of hyperprolactinemia: general approach and reproductive health implications. Arch. Med. Res. 55(8), 103102 (2024)","journal-title":"Arch. Med. Res."},{"issue":"5","key":"4433_CR16","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1007\/s11102-023-01337-0","volume":"26","author":"L Billion","year":"2023","unstructured":"L. Billion, A. Verleye, C. Block, P.V. Heyning, C. Herdt, Giant prolactinomas, a detailed analysis of 196 adult cases. Pituitary. 26(5), 529\u2013537 (2023)","journal-title":"Pituitary"},{"issue":"1","key":"4433_CR17","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1093\/ejendo\/lvad070","volume":"189","author":"R Hamblin","year":"2023","unstructured":"R. Hamblin, A. Fountas, K. Lithgow, P.B. Loughrey, E. Bonanos, S.K. Shinwari et al., Natural history of non-functioning pituitary microadenomas: results from the UK non-functioning pituitary adenoma consortium. Eur. J. Endocrinol. 189(1), 87\u201395 (2023)","journal-title":"Eur. J. Endocrinol."},{"issue":"3","key":"4433_CR18","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1111\/j.1365-2265.2006.02461.x","volume":"64","author":"M De Rosa","year":"2006","unstructured":"De M. Rosa, A. Ciccarelli, S. Zarrilli, E. Guerra, M. Gaccione, Di A. Sarno et al., The treatment with Cabergoline for 24 month normalizes the quality of seminal fluid in hyperprolactinaemic males. Clin. Endocrinol. (Oxf). 64(3), 307\u2013313 (2006)","journal-title":"Clin. Endocrinol. (Oxf)"},{"key":"4433_CR19","doi-asserted-by":"publisher","first-page":"1363939","DOI":"10.3389\/fendo.2024.1363939","volume":"15","author":"S Hofbauer","year":"2024","unstructured":"S. Hofbauer, L. Horka, S. Seidenberg, R. Da Mutten, L. Regli, C. Serra et al., Metabolic and inflammatory parameters in relation to baseline characterization and treatment outcome in patients with prolactinoma: insights from a retrospective cohort study at a single tertiary center. Front. Endocrinol. (Lausanne). 15, 1363939 (2024)","journal-title":"Front. Endocrinol. (Lausanne)"},{"issue":"1","key":"4433_CR20","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1186\/s12902-021-00733-6","volume":"21","author":"AS Posawetz","year":"2021","unstructured":"A.S. Posawetz, C. Trummer, M. Pandis, F. Aberer, T.R. Pieber, B. Obermayer-Pietsch et al., Adverse body composition and lipid parameters in patients with prolactinoma: a case-control study. BMC Endocr. Disord. 21(1), 81 (2021)","journal-title":"BMC Endocr. Disord"},{"issue":"4","key":"4433_CR21","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1016\/j.tem.2020.01.004","volume":"31","author":"Y Macotela","year":"2020","unstructured":"Y. Macotela, J. Triebel, C. Clapp, Time for a new perspective on prolactin in metabolism. Trends Endocrinol. Metab. 31(4), 276\u2013286 (2020)","journal-title":"Trends Endocrinol. Metab."},{"issue":"4","key":"4433_CR22","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1210\/er.2017-00025","volume":"38","author":"AL Goldman","year":"2017","unstructured":"A.L. Goldman, S. Bhasin, F.C.W. Wu, M. Krishna, A.M. Matsumoto, R. Jasuja, A reappraisal of testosterone\u2019s binding in circulation: physiological and clinical implications. Endocr. Rev. 38(4), 302\u2013324 (2017)","journal-title":"Endocr. Rev."},{"issue":"7","key":"4433_CR23","doi-asserted-by":"publisher","first-page":"1618","DOI":"10.2337\/dc09-1788","volume":"33","author":"C Li","year":"2010","unstructured":"C. Li, E.S. Ford, B. Li, W.H. Giles, S. Liu, Association of testosterone and sex hormone-binding Globulin with metabolic syndrome and insulin resistance in men. Diabetes Care. 33(7), 1618\u20131624 (2010)","journal-title":"Diabetes Care"}],"container-title":["Endocrine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12020-025-04433-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12020-025-04433-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12020-025-04433-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T18:03:44Z","timestamp":1765908224000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12020-025-04433-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,20]]},"references-count":23,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["4433"],"URL":"https:\/\/doi.org\/10.1007\/s12020-025-04433-2","relation":{},"ISSN":["1559-0100"],"issn-type":[{"value":"1559-0100","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,20]]},"assertion":[{"value":"3 April 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 September 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 September 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}