{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T02:56:18Z","timestamp":1791255378683,"version":"4.1.0"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T00:00:00Z","timestamp":1769990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T00:00:00Z","timestamp":1769990400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/100012542","name":"Sichuan Provincial Science and Technology Support Program","doi-asserted-by":"publisher","award":["No. 23ZDYF2116"],"award-info":[{"award-number":["No. 23ZDYF2116"]}],"id":[{"id":"10.13039\/100012542","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013365","name":"West China Hospital, Sichuan University","doi-asserted-by":"publisher","award":["2021HXFH008"],"award-info":[{"award-number":["2021HXFH008"]}],"id":[{"id":"10.13039\/501100013365","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Endocrine"],"DOI":"10.1007\/s12020-025-04481-8","type":"journal-article","created":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T08:01:19Z","timestamp":1770019279000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Intraindividual variability of aldosterone and the aldosterone-to-renin ratio detected by LC-MS\/MS and their impact factors in patients with hypertension"],"prefix":"10.1007","volume":"91","author":[{"given":"Jia","family":"Tang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingting","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyu","family":"Pu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenxiao","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4519-397X","authenticated-orcid":false,"given":"Yan","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,2]]},"reference":[{"issue":"2","key":"4481_CR1","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1210\/er.2017-00054","volume":"38","author":"WF Young","year":"2017","unstructured":"W.F. Young, D.A. Calhoun, J.W.M. Lenders, M. Stowasser, S.C. Textor, Screening for endocrine hypertension: an endocrine society scientific statement. Endocr. Rev. 38(2), 103\u2013122 (2017). https:\/\/doi.org\/10.1210\/er.2017-00054","journal-title":"Endocr. Rev."},{"issue":"14","key":"4481_CR2","doi-asserted-by":"publisher","first-page":"1811","DOI":"10.1016\/j.jacc.2017.01.052","volume":"69","author":"S Monticone","year":"2017","unstructured":"S. Monticone, J. Burrello, D. Tizzani et al., Prevalence and clinical manifestations of primary aldosteronism encountered in primary care practice. J. Am. Coll. Cardiol. 69(14), 1811\u20131820 (2017). https:\/\/doi.org\/10.1016\/j.jacc.2017.01.052","journal-title":"J. Am. Coll. Cardiol."},{"issue":"16","key":"4481_CR3","doi-asserted-by":"publisher","first-page":"1913","DOI":"10.1016\/j.jacc.2020.02.052","volume":"75","author":"Z Xu","year":"2020","unstructured":"Z. Xu, J. Yang, J. Hu et al., Primary aldosteronism in patients in China with recently detected hypertension. J. Am. Coll. Cardiol. 75(16), 1913\u20131922 (2020). https:\/\/doi.org\/10.1016\/j.jacc.2020.02.052","journal-title":"J. Am. Coll. Cardiol."},{"issue":"5","key":"4481_CR4","doi-asserted-by":"publisher","first-page":"1889","DOI":"10.1210\/jc.2015-4061","volume":"101","author":"JW Funder","year":"2016","unstructured":"J.W. Funder, R.M. Carey, F. Mantero et al., The management of primary aldosteronism: case Detection, Diagnosis, and treatment: an endocrine society clinical practice guideline. J. Clin. Endocrinol. Metab. 101(5), 1889\u20131916 (2016). https:\/\/doi.org\/10.1210\/jc.2015-4061","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"10","key":"4481_CR5","doi-asserted-by":"publisher","first-page":"1919","DOI":"10.1097\/hjh.0000000000002510","volume":"38","author":"P Mulatero","year":"2020","unstructured":"P. Mulatero, S. Monticone, J. Deinum et al., Genetics, prevalence, screening and confirmation of primary aldosteronism: a position statement and consensus of the working group on endocrine hypertension of the European society of hypertension. J. Hypertens. 38(10), 1919\u20131928 (2020). https:\/\/doi.org\/10.1097\/hjh.0000000000002510","journal-title":"J. Hypertens."},{"issue":"4","key":"4481_CR6","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1507\/endocrj.EJ21-0508","volume":"69","author":"M Naruse","year":"2021","unstructured":"M. Naruse, T. Katabami, H. Shibata et al., Japan endocrine society clinical practice guideline for the diagnosis and management of primary aldosteronism 2021. Endocr. J. 69(4), 327\u2013359 (2021). https:\/\/doi.org\/10.1507\/endocrj.EJ21-0508","journal-title":"Endocr. J."},{"issue":"3","key":"4481_CR7","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1161\/hypertensionaha.120.16429","volume":"77","author":"N Yozamp","year":"2021","unstructured":"N. Yozamp, G.L. Hundemer, M. Moussa, J. Underhill, T. Fudim, B. Sacks, A. Vaidya, Intraindividual variability of aldosterone concentrations in primary aldosteronism: implications for case detection. Hypertension. 77(3), 891\u2013899 (2021). https:\/\/doi.org\/10.1161\/hypertensionaha.120.16429","journal-title":"Hypertension"},{"issue":"5","key":"4481_CR8","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1210\/clinem\/dgac679","volume":"108","author":"AW Maciel","year":"2023","unstructured":"A.W. Maciel, T.C. Freitas, G.F.C. Fagundes et al., Intra-individual variability of serum aldosterone and implications for primary aldosteronism screening. J. Clin. Endocrinol. Metab. 108(5), 1143\u20131153 (2023). https:\/\/doi.org\/10.1210\/clinem\/dgac679","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"1","key":"4481_CR9","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1210\/clinem\/dgac568","volume":"108","author":"E Ng","year":"2022","unstructured":"E. Ng, S.M. Gwini, R. Libianto et al., Aldosterone, Renin and ARR variability in screening for primary aldosteronism. J. Clin. Endocrinol. Metab. 108(1), 33\u201341 (2022). https:\/\/doi.org\/10.1210\/clinem\/dgac568","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"9","key":"4481_CR10","doi-asserted-by":"publisher","first-page":"1477","DOI":"10.1515\/cclm-2019-0869","volume":"58","author":"ZX Wang","year":"2020","unstructured":"Z.X. Wang, H. Wang, Y.F. Peng et al., A liquid chromatograph-tandem mass spectrometry (LC-MS\/MS)-based assay to profile 20 plasma steroids in endocrine disorders. Clin. Chem. Lab. Med. 58(9), 1477\u20131487 (2020). https:\/\/doi.org\/10.1515\/cclm-2019-0869","journal-title":"Clin. Chem. Lab. Med."},{"issue":"13\u201314","key":"4481_CR11","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.1016\/j.clinbiochem.2012.11.030","volume":"46","author":"M Yazdanpanah","year":"2013","unstructured":"M. Yazdanpanah, D. Bailey, W. Walsh, B. Wan, K. Adeli, Analytical measurement of serum 25-OH-vitamin D (3), 25-OH-vitamin D (2) and their C3-epimers by LC-MS\/MS in infant and pediatric specimens. Clin. Biochem. 46(13\u201314), 1264\u20131271 (2013). https:\/\/doi.org\/10.1016\/j.clinbiochem.2012.11.030","journal-title":"Clin. Biochem."},{"issue":"18","key":"4481_CR12","doi-asserted-by":"publisher","first-page":"1903","DOI":"10.4155\/bio-2016-0111","volume":"8","author":"R Fuertig","year":"2016","unstructured":"R. Fuertig, A. Ceci, S.M. Camus, E. Bezard, A.H. Luippold, B. Hengerer, LC-MS\/MS-based quantification of kynurenine metabolites, tryptophan, monoamines and neopterin in plasma, cerebrospinal fluid and brain. Bioanalysis. 8(18), 1903\u20131917 (2016). https:\/\/doi.org\/10.4155\/bio-2016-0111","journal-title":"Bioanalysis"},{"issue":"6","key":"4481_CR13","doi-asserted-by":"publisher","first-page":"982","DOI":"10.1097\/hjh.0000000000002453","volume":"38","author":"T Unger","year":"2020","unstructured":"T. Unger, C. Borghi, F. Charchar et al., 2020 international society of hypertension global hypertension practice guidelines. J. Hypertens. 38(6), 982\u20131004 (2020). https:\/\/doi.org\/10.1097\/hjh.0000000000002453","journal-title":"J. Hypertens."},{"issue":"11","key":"4481_CR14","doi-asserted-by":"publisher","first-page":"2269","DOI":"10.1097\/HJH.0000000000001855","volume":"36","author":"H Kobayashi","year":"2018","unstructured":"H. Kobayashi, M. Abe, M. Soma et al., Development and validation of subtype prediction scores for the workup of primary aldosteronism. J. Hypertens. 36(11), 2269\u20132276 (2018). https:\/\/doi.org\/10.1097\/HJH.0000000000001855","journal-title":"J. Hypertens."},{"issue":"2","key":"4481_CR15","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1007\/s12020-024-03899-w","volume":"85","author":"Q Zhang","year":"2024","unstructured":"Q. Zhang, Z. Zhao, W. Cheng, Y. Zhang, Z. Li, H. Liu, Effects of sodium intake, age, gender, blood sampling time on distribution of plasma aldosterone, Renin activity, deoxycorticosterone, cortisol, cortisone, and 24\u00a0h urinary aldosterone levels in normotensive individuals based on LC-MS\/MS. Endocrine. 85(2), 947\u2013954 (2024). https:\/\/doi.org\/10.1007\/s12020-024-03899-w","journal-title":"Endocrine"},{"issue":"1","key":"4481_CR16","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/s2213-8587(17)30319-4","volume":"6","author":"S Monticone","year":"2018","unstructured":"S. Monticone, F. D\u2019Ascenzo, C. Moretti et al., Cardiovascular events and target organ damage in primary aldosteronism compared with essential hypertension: a systematic review and meta-analysis. Lancet Diabetes Endocrinol. 6(1), 41\u201350 (2018). https:\/\/doi.org\/10.1016\/s2213-8587(17)30319-4","journal-title":"Lancet Diabetes Endocrinol."},{"issue":"1","key":"4481_CR17","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1097\/hjh.0000000000002216","volume":"38","author":"S Monticone","year":"2020","unstructured":"S. Monticone, E. Sconfienza, F. D\u2019Ascenzo et al., Renal damage in primary aldosteronism: a systematic review and meta-analysis. J. Hypertens. 38(1), 3\u201312 (2020). https:\/\/doi.org\/10.1097\/hjh.0000000000002216","journal-title":"J. Hypertens."},{"issue":"12","key":"4481_CR18","doi-asserted-by":"publisher","first-page":"4826","DOI":"10.1210\/jc.2013-2805","volume":"98","author":"P Mulatero","year":"2013","unstructured":"P. Mulatero, S. Monticone, C. Bertello et al., Long-term cardio- and cerebrovascular events in patients with primary aldosteronism. J. Clin. Endocrinol. Metab. 98(12), 4826\u20134833 (2013). https:\/\/doi.org\/10.1210\/jc.2013-2805","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"5","key":"4481_CR19","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1097\/hjh.0000000000001251","volume":"35","author":"M Murata","year":"2017","unstructured":"M. Murata, T. Kitamura, D. Tamada et al., Plasma aldosterone level within the normal range is less associated with cardiovascular and cerebrovascular risk in primary aldosteronism. J. Hypertens. 35(5), 1079\u20131085 (2017). https:\/\/doi.org\/10.1097\/hjh.0000000000001251","journal-title":"J. Hypertens."},{"issue":"8","key":"4481_CR20","doi-asserted-by":"publisher","first-page":"2423","DOI":"10.1210\/clinem\/dgab348","volume":"106","author":"A Hung","year":"2021","unstructured":"A. Hung, S. Ahmed, A. Gupta et al., Performance of the aldosterone to Renin ratio as a screening test for primary aldosteronism. J. Clin. Endocrinol. Metab. 106(8), 2423\u20132435 (2021). https:\/\/doi.org\/10.1210\/clinem\/dgab348","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"3","key":"4481_CR21","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1055\/s-0031-1295460","volume":"44","author":"M Stowasser","year":"2012","unstructured":"M. Stowasser, A.H. Ahmed, E. Pimenta, P.J. Taylor, R.D. Gordon, Factors affecting the aldosterone\/renin ratio. Horm. Metab. Res. 44(3), 170\u2013176 (2012). https:\/\/doi.org\/10.1055\/s-0031-1295460","journal-title":"Horm. Metab. Res."},{"issue":"1","key":"4481_CR22","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1210\/endrev\/bnad026","volume":"45","author":"N Mullen","year":"2024","unstructured":"N. Mullen, J. Curneen, P.T. Donlon, P. Prakash, I. Bancos, M. Gurnell, M.C. Dennedy, Treating primary aldosteronism-induced hypertension: novel approaches and future outlooks. Endocr. Rev. 45(1), 125\u2013170 (2024). https:\/\/doi.org\/10.1210\/endrev\/bnad026","journal-title":"Endocr. Rev."},{"issue":"1","key":"4481_CR23","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1210\/jc.2004-1149","volume":"90","author":"SC Tiu","year":"2005","unstructured":"S.C. Tiu, C.H. Choi, C.C. Shek, Y.W. Ng, F.K. Chan, C.M. Ng, A.P. Kong, The use of aldosterone-renin ratio as a diagnostic test for primary hyperaldosteronism and its test characteristics under different conditions of blood sampling. J. Clin. Endocrinol. Metab. 90(1), 72\u201378 (2005). https:\/\/doi.org\/10.1210\/jc.2004-1149","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"4481_CR24","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.clinms.2018.06.002","volume":"9","author":"CM Le Goff","year":"2018","unstructured":"C.M. Le Goff, A. Gonzalez-Antuna, S.D. Peeters et al., Migration from RIA to LC-MS\/MS for aldosterone determination: implications for clinical practice and determination of plasma and urine reference range intervals in a cohort of healthy Belgian subjects. Clin. Mass. Spectrom. 9, 7\u201317 (2018). https:\/\/doi.org\/10.1016\/j.clinms.2018.06.002","journal-title":"Clin. Mass. Spectrom."},{"issue":"5","key":"4481_CR25","doi-asserted-by":"publisher","first-page":"e2027","DOI":"10.1210\/clinem\/dgab924","volume":"107","author":"G. Eisenhofer","year":"2022","unstructured":"G. Eisenhofer, M. Kurlbaum, M. Peitzsch et al., The Saline Infusion Test for Primary Aldosteronism: Implications of Immunoassay Inaccuracy. J. Clin. Endocrinol. Metab. (2022).107(5), e2027-e2036 https:\/\/doi.org\/10.1210\/clinem\/dgab924","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"6","key":"4481_CR26","doi-asserted-by":"publisher","first-page":"bvac049","DOI":"10.1210\/jendso\/bvac049","volume":"6","author":"JM Brown","year":"2022","unstructured":"J.M. Brown, R.J. Auchus, B. Honzel, J.M. Luther, N. Yozamp, A. Vaidya, Recalibrating interpretations of aldosterone assays across the physiologic range: immunoassay and liquid chromatography-tandem mass spectrometry measurements under multiple controlled conditions. J. Endocr. Soc. 6(6), bvac049 (2022). https:\/\/doi.org\/10.1210\/jendso\/bvac049","journal-title":"J. Endocr. Soc."},{"issue":"3","key":"4481_CR27","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1093\/jalm\/jfaa177","volume":"6","author":"SM Gibbons","year":"2021","unstructured":"S.M. Gibbons, H.P. Field, A. Fairhurst, A. Fleming, C. Ford, E.L. Williams, S.C. Barnes, J.H. Barth, Clinical evaluation of assays for plasma Renin activity and aldosterone measurement by liquid chromatography-tandem mass spectrometry. J. Appl. Lab. Med. 6(3), 668\u2013678 (2021). https:\/\/doi.org\/10.1093\/jalm\/jfaa177","journal-title":"J. Appl. Lab. Med."},{"issue":"1","key":"4481_CR28","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1093\/ajh\/hpaa151","volume":"34","author":"N Yozamp","year":"2021","unstructured":"N. Yozamp, G.L. Hundemer, M. Moussa, J. Underhill, T. Fudim, B. Sacks, A. Vaidya, Variability of aldosterone measurements during adrenal venous sampling for primary aldosteronism. Am. J. Hypertens. 34(1), 34\u201345 (2021). https:\/\/doi.org\/10.1093\/ajh\/hpaa151","journal-title":"Am. J. Hypertens."},{"issue":"2","key":"4481_CR29","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1006\/abio.1997.2340","volume":"252","author":"VF Fredline","year":"1997","unstructured":"V.F. Fredline, P.J. Taylor, H.M. Dodds, A.G. Johnson, A reference method for the analysis of aldosterone in blood by high-performance liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry. Anal. Biochem. 252(2), 308\u2013313 (1997). https:\/\/doi.org\/10.1006\/abio.1997.2340","journal-title":"Anal. Biochem."},{"issue":"1","key":"4481_CR30","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1161\/hypertensionaha.119.13772","volume":"75","author":"J Burrello","year":"2020","unstructured":"J. Burrello, F. Buffolo, O. Domenig et al., Renin-Angiotensin-Aldosterone system Triple-A analysis for the screening of primary aldosteronism. Hypertension. 75(1), 163\u2013172 (2020). https:\/\/doi.org\/10.1161\/hypertensionaha.119.13772","journal-title":"Hypertension"},{"issue":"3","key":"4481_CR31","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1097\/hjh.0000000000001905","volume":"37","author":"GA Kline","year":"2019","unstructured":"G.A. Kline, P. Darras, A.A. Leung, B. So, A. Chin, D.T. Holmes, Surprisingly low aldosterone levels in peripheral veins following intravenous sedation during adrenal vein sampling: implications for the concept of nonsuppressibility in primary aldosteronism. J. Hypertens. 37(3), 596\u2013602 (2019). https:\/\/doi.org\/10.1097\/hjh.0000000000001905","journal-title":"J. Hypertens."},{"issue":"1","key":"4481_CR32","doi-asserted-by":"publisher","first-page":"10","DOI":"10.7326\/M20-0065","volume":"173","author":"JM Brown","year":"2020","unstructured":"J.M. Brown, M. Siddiqui, D.A. Calhoun, R.M. Carey, P.N. Hopkins, G.H. Williams, A. Vaidya, The unrecognized prevalence of primary aldosteronism: A Cross-sectional study. Ann. Intern. Med. 173(1), 10\u201320 (2020). https:\/\/doi.org\/10.7326\/M20-0065","journal-title":"Ann. Intern. Med."},{"issue":"6","key":"4481_CR33","doi-asserted-by":"publisher","first-page":"2489","DOI":"10.1210\/jc.2002-021476","volume":"88","author":"A Tanabe","year":"2003","unstructured":"A. Tanabe, M. Naruse, S. Takagi, K. Tsuchiya, T. Imaki, K. Takano, Variability in the renin\/aldosterone profile under random and standardized sampling conditions in primary aldosteronism. J. Clin. Endocrinol. Metab. 88(6), 2489\u20132494 (2003). https:\/\/doi.org\/10.1210\/jc.2002-021476","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"7","key":"4481_CR34","doi-asserted-by":"publisher","first-page":"1592","DOI":"10.1097\/hjh.0000000000001735","volume":"36","author":"S Baron","year":"2018","unstructured":"S. Baron, L. Amar, A.L. Faucon et al., Criteria for diagnosing primary aldosteronism on the basis of liquid chromatography-tandem mass spectrometry determinations of plasma aldosterone concentration. J. Hypertens. 36(7), 1592\u20131601 (2018). https:\/\/doi.org\/10.1097\/hjh.0000000000001735","journal-title":"J. Hypertens."},{"issue":"9","key":"4481_CR35","doi-asserted-by":"publisher","first-page":"2453","DOI":"10.1210\/clinem\/dgaf284","volume":"110","author":"GK Adler","year":"2025","unstructured":"G.K. Adler, M. Stowasser, R.R. Correa et al., Primary aldosteronism: an endocrine society clinical practice guideline. J. Clin. Endocrinol. Metab. 110(9), 2453\u20132495 (2025). https:\/\/doi.org\/10.1210\/clinem\/dgaf284","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"11","key":"4481_CR36","doi-asserted-by":"publisher","first-page":"2256","DOI":"10.1097\/hjh.0000000000003257","volume":"40","author":"GP Veldhuizen","year":"2022","unstructured":"G.P. Veldhuizen, R.M. Alnazer, A.A. Kroon, P.W. de Leeuw, Variability of aldosterone, Renin and the aldosterone-to-renin ratio in hypertensive patients without primary aldosteronism. J. Hypertens. 40(11), 2256\u20132262 (2022). https:\/\/doi.org\/10.1097\/hjh.0000000000003257","journal-title":"J. Hypertens."},{"issue":"2","key":"4481_CR37","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1038\/jhh.2008.109","volume":"23","author":"E Fommei","year":"2009","unstructured":"E. Fommei, S. Ghione, A. Ripoli, S. Maffei, P. Di Cecco, A. Iervasi, S. Turchi, The ovarian cycle as a factor of variability in the laboratory screening for primary aldosteronism in women. J. Hum. Hypertens. 23(2), 130\u2013135 (2009). https:\/\/doi.org\/10.1038\/jhh.2008.109","journal-title":"J. Hum. Hypertens."},{"issue":"6","key":"4481_CR38","doi-asserted-by":"publisher","first-page":"960","DOI":"10.1161\/circresaha.116.303587","volume":"116","author":"L Te Riet","year":"2015","unstructured":"L. Te Riet, J.H. van Esch, A.J. Roks, A.H. van den Meiracker, A.H. Danser, Hypertension: renin-angiotensin-aldosterone system alterations. Circ. Res. 116(6), 960\u2013975 (2015). https:\/\/doi.org\/10.1161\/circresaha.116.303587","journal-title":"Circ. Res."}],"container-title":["Endocrine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12020-025-04481-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12020-025-04481-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12020-025-04481-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T08:01:20Z","timestamp":1770019280000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12020-025-04481-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,2]]},"references-count":38,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["4481"],"URL":"https:\/\/doi.org\/10.1007\/s12020-025-04481-8","relation":{},"ISSN":["1559-0100"],"issn-type":[{"value":"1559-0100","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,2]]},"assertion":[{"value":"12 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 December 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 February 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the Ethics Committee of the West China Hospital of Sichuan University (no. 2019\u2009\u2212\u2009692) and was performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Written informed consent was obtained from each patient.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate<!--Emphasis Type='Bold' removed-->and publish"}},{"value":"The authors affirm that human research participants provided informed consent for publication.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"50"}}