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Body Image Scale (BIS), Toronto Alexithymia Score-20 (TAS-20), Hospital Anxiety and Depression inventory (HAD), Short Form-36 (SF-36) and Acromegaly Quality of Life Scale (AcroQol) were used to the patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In the acromegaly group, TAS-20 total scores, as well as the Difficulty Identifying Feelings (DIF) and Difficulty Describing Feelings (DDF) subscale scores, were higher compared to the control group (51 vs. 44,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01; 16 vs. 12,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01; and 12 vs. 11,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01, respectively). In contrast, no notable difference was observed in the Externally Oriented Thinking (EOT) scores between the groups. The prevalence of alexithymia was markedly higher in individuals with acromegaly (16.7%) than in the control group (3.2%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). A positive correlation was found between alexithymia and both depression and anxiety scores (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.469,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001;\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.377,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01, respectively). In contrast, alexithymia was negatively correlated with SF-36, AcroQoL and BIS (\n                      <jats:italic>r<\/jats:italic>\n                      = \u2212\u20090.426,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01;\n                      <jats:italic>r<\/jats:italic>\n                      = \u2212\u20090.465,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01;\n                      <jats:italic>r<\/jats:italic>\n                      = \u2212\u20090.364,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01, respectively). Patients with acromegaly reported poorer body image and a higher rate of impaired body perception compared to control group (43.7% vs. 19.2%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The present study demonstrates that alexithymia is more prevalent in patients with acromegaly compared to controls and often persists even after remission.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s12020-026-04606-7","type":"journal-article","created":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T07:55:50Z","timestamp":1775116550000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The silent burden: Alexithymia and quality of life in acromegaly patients"],"prefix":"10.1007","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4420-4721","authenticated-orcid":false,"given":"Lala","family":"Soltanova","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4568-3729","authenticated-orcid":false,"given":"Ahmet Bera","family":"Aygun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9281-1771","authenticated-orcid":false,"given":"Banu Betul","family":"Kocaman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1906-0535","authenticated-orcid":false,"given":"Ilkin","family":"Muradov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabriye Sibel","family":"Taze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8684-2617","authenticated-orcid":false,"given":"Senol","family":"Turan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8329-140X","authenticated-orcid":false,"given":"Pinar","family":"Kadioglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6803-4977","authenticated-orcid":false,"given":"Emre","family":"Durcan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,2]]},"reference":[{"issue":"1","key":"4606_CR1","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1210\/er.2018-00115","volume":"40","author":"MR Gadelha","year":"2018","unstructured":"M.R. 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