{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T03:00:53Z","timestamp":1791946853517,"version":"4.3.4"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2020,3,14]],"date-time":"2020-03-14T00:00:00Z","timestamp":1584144000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,3,14]],"date-time":"2020-03-14T00:00:00Z","timestamp":1584144000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Forensic Sci Med Pathol"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Transcatheter aortic valve implantation (TAVI) represents a catheter-based and minimally invasive replacement of the aortic valve. TAVI is considered to be a relatively safe procedure and has evolved to a standard procedure in inoperable and high-risk patients with aortic stenosis. We present a case of an octogenarian who died in hospital less than a day after an initially satisfactory TAVI. Cardiologists suspected a combination of cardiogenic and hemorrhagic shock as the cause of death. Autopsy showed rupture of an extensive aortic dissection, which had developed within 24\u00a0h after the procedure. The cause of death was eventually defined as internal bleeding due to a rapid two-stage vascular process. The manner of death was considered accidental because an iatrogenic vessel injury beyond the aortic arch was causative for the death. This unusual case highlights the potential for rare, but fatal, complications within the scope of cardiac catheterizations, such as TAVI. Additionally, our findings suggest that these complications need to be recognized in the diagnostic process and management of post-interventional complications.<\/jats:p>","DOI":"10.1007\/s12024-020-00219-2","type":"journal-article","created":{"date-parts":[[2020,3,14]],"date-time":"2020-03-14T19:03:15Z","timestamp":1584212595000},"page":"335-339","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Rapid development of an iatrogenic aortic dissection following transcatheter aortic valve implantation"],"prefix":"10.1007","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7798-4429","authenticated-orcid":false,"given":"Julian","family":"Geile","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elke","family":"Doberentz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burkhard","family":"Madea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,3,14]]},"reference":[{"key":"219_CR1","doi-asserted-by":"publisher","first-page":"483","DOI":"10.4065\/mcp.2009.0706","volume":"85","author":"K Maganti","year":"2010","unstructured":"Maganti K, Rigolin VH, Sarano ME, Bonow RO. Valvular heart disease: diagnosis and management. Mayo Clin Proc. 2010;85:483\u2013500.","journal-title":"Mayo Clin Proc"},{"key":"219_CR2","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1093\/ehjci\/jew335","volume":"18","author":"H Baumgartner","year":"2017","unstructured":"Baumgartner H, Hung J, Bermejo J, Chambers JB, Edvardsen T, Goldstein S, et al. Recommendations on the echocardiographic assessment of aortic valve stenosis: a focused update from the European Association of Cardiovascular Imaging and the American Society of Echocardiography. Eur Heart J Cardiovasc Imaging. 2017;18:254\u201375.","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"219_CR3","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/j.acvd.2012.01.005","volume":"105","author":"A Cribier","year":"2012","unstructured":"Cribier A. Development of transcatheter aortic valve implantation (TAVI): a 20-year odyssey. Arch Cardiovasc Dis. 2012;105:146\u201352.","journal-title":"Arch Cardiovasc Dis"},{"key":"219_CR4","first-page":"51","volume":"12","author":"G Costa","year":"2018","unstructured":"Costa G, Barbanti M, Tamburino C. Trends in European TAVI practice. Cardiac Interventions Today. 2018;12:51\u20134.","journal-title":"Cardiac Interventions Today"},{"key":"219_CR5","doi-asserted-by":"publisher","first-page":"e1549","DOI":"10.4244\/EIJ-D-18-01010","volume":"14","author":"H Eggebrecht","year":"2019","unstructured":"Eggebrecht H, Mehta RH. Transcatheter aortic valve implantation (TAVI) in Germany: more than 100,000 procedures and now the standard of care for the elderly. EuroIntervention. 2019;14:e1549\u201352.","journal-title":"EuroIntervention."},{"key":"219_CR6","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1055\/s-0038-1676131","volume":"66","author":"A Beckmann","year":"2018","unstructured":"Beckmann A, Meyer R, Lewandowski J, Frie M, Markewitz A, Harringer W. German heart surgery report 2017: the annual updated registry of the German society for thoracic and cardiovascular surgery. Thorac Cardiovasc Surg. 2018;66:608\u201321.","journal-title":"Thorac Cardiovasc Surg"},{"key":"219_CR7","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1016\/j.jacc.2016.11.033","volume":"69","author":"FL Grover","year":"2017","unstructured":"Grover FL, Vemulapalli S, Carroll JD, Edwards F, Mack MJ, Thourani VH, et al. 2016 annual report of the Society of Thoracic Surgeons\/American College of Cardiology Transcatheter Valve Therapy Registry. J Am Coll Cardiol. 2017;69:1215\u201330.","journal-title":"J Am Coll Cardiol"},{"key":"219_CR8","unstructured":"Carrozza JP. Complications of diagnostic cardiac catheterization. https:\/\/www.uptodate.com\/contents\/complications-of-diagnostic-cardiac-catheterization#H186337600. Accessed 12 Sept 2019."},{"key":"219_CR9","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/j.ijcard.2017.01.088","volume":"241","author":"Z Dimitriadis","year":"2017","unstructured":"Dimitriadis Z, Scholtz W, B\u00f6rgermann J, Wiemer M, Piper C. Impact of closure devices on vascular complication and mortality rates in TAVI procedures. Int J Cardiol. 2017;241:133\u20137.","journal-title":"Int J Cardiol"},{"key":"219_CR10","doi-asserted-by":"publisher","first-page":"2173","DOI":"10.1016\/j.jacc.2015.03.034","volume":"65","author":"T Walther","year":"2015","unstructured":"Walther T, Hamm CW, Schuler G, Berkowitsch A, K\u00f6tting J, Mangner N, et al. Perioperative results and complications in 15,964 transcatheter aortic valve replacements: prospective data from the GARY registry. J Am Coll Cardiol. 2015;65:2173\u201380.","journal-title":"J Am Coll Cardiol"},{"key":"219_CR11","doi-asserted-by":"publisher","unstructured":"Langer NB, Hamid NB, Nazif TM, Khalique OK, Vahl TP, White J, et al. Injuries to the aorta, aortic annulus, and left ventricle during transcatheter aortic valve replacement: management and outcomes. Circ Cardiovasc Interv. 2017;10. https:\/\/doi.org\/10.1161\/CIRCINTERVENTIONS.116.004735.","DOI":"10.1161\/CIRCINTERVENTIONS.116.004735"},{"key":"219_CR12","unstructured":"Dalby M, Transcatheter aortic valve implantation: . https:\/\/www.uptodate.com\/contents\/transcatheter-aortic-valve-implantation-complications#H1037080415. Accessed 12 Sept 2019."},{"key":"219_CR13","doi-asserted-by":"publisher","first-page":"20130595","DOI":"10.1259\/bjr.20130595","volume":"87","author":"B Clayton","year":"2014","unstructured":"Clayton B, Morgan-Hughes G, Roobottom C. Transcatheter aortic valve insertion (TAVI): a review. Br J Radiol. 2014;87:20130595.","journal-title":"Br J Radiol"},{"key":"219_CR14","first-page":"1211","volume":"73","author":"JM Porcel","year":"2006","unstructured":"Porcel JM, Light RW. Diagnostic approach to pleural effusion in adults. Am Fam Physician. 2006;73:1211\u201320.","journal-title":"Am Fam Physician"},{"key":"219_CR15","doi-asserted-by":"publisher","first-page":"e14","DOI":"10.1161\/CIRCULATIONAHA.115.019824","volume":"133","author":"JA de Agustin","year":"2016","unstructured":"de Agustin JA, Jim\u00e9nez-Quevedo P, Nombela-Franco L, Almeria C, Gomez de Diego JJ, Rodrigo JL, et al. Descending aorta rupture during transcatheter aortic valve replacement. Circulation. 2016;133:e14\u20137.","journal-title":"Circulation."},{"key":"219_CR16","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1111\/jocs.13813","volume":"33","author":"N Omran","year":"2018","unstructured":"Omran N, Kvasnak M, Derner M, Cervinka P. Endovascular management of an aortic rupture following transcatheter aortic valve replacement. J Card Surg. 2018;33:631\u20133.","journal-title":"J Card Surg"},{"key":"219_CR17","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1002\/ccd.22532","volume":"76","author":"RT Gerber","year":"2010","unstructured":"Gerber RT, Osborn M, Mikhail GW. Delayed mortality from aortic dissection post transcatheter aortic valve implantation (TAVI): the tip of the iceberg. Catheter Cardiovasc Interv. 2010;76:202\u20134.","journal-title":"Catheter Cardiovasc Interv"},{"key":"219_CR18","doi-asserted-by":"publisher","first-page":"68","DOI":"10.14740\/cr537w","volume":"8","author":"A Shofu","year":"2017","unstructured":"Shofu A, Awan GM, Omar B, Qureshi G. Late presentation of aortic aneurysm and dissection following cardiac catheterization. Cardiol Res. 2017;8:68\u201372.","journal-title":"Cardiol Res"},{"key":"219_CR19","doi-asserted-by":"publisher","unstructured":"Losmanova T, Tosoni I, Fahrni S, Ballmer PE. Autopsy case of aortic dissection after transcatheter aortic valve implantation (TAVI). BMJ Case Rep. 2018;2018. https:\/\/doi.org\/10.1136\/bcr-2017-220105.","DOI":"10.1136\/bcr-2017-220105"},{"key":"219_CR20","doi-asserted-by":"publisher","first-page":"554","DOI":"10.4103\/0971-9784.185564","volume":"19","author":"NG Baikoussis","year":"2016","unstructured":"Baikoussis NG, Argiriou M, Kratimenos T, Karameri V, Dedeilias P. Iatrogenic dissection of the descending aorta: conservative or endovascular treatment? Ann Card Anaesth. 2016;19:554\u20136.","journal-title":"Ann Card Anaesth"},{"key":"219_CR21","doi-asserted-by":"publisher","first-page":"E391","DOI":"10.1002\/ccd.27994","volume":"93","author":"E Jacobzon","year":"2019","unstructured":"Jacobzon E, Wolak A, Fink D, Silberman S. Delayed aortic dissection and valve thrombosis after transcatheter aortic valve implantation. Catheter Cardiovasc Interv. 2019;93:E391\u20133.","journal-title":"Catheter Cardiovasc Interv"},{"key":"219_CR22","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1016\/j.jcin.2012.08.029","volume":"6","author":"Z Dahdouh","year":"2013","unstructured":"Dahdouh Z, Roule V, Lognon\u00e9 T, Sabatier R, Grollier G. Aortic arch rupture: an uncommon but fatal complication during transcatheter aortic valve implantation. JACC Cardiovasc Interv. 2013;6:416\u20137.","journal-title":"JACC Cardiovasc Interv"},{"key":"219_CR23","doi-asserted-by":"publisher","first-page":"1076","DOI":"10.1002\/ccd.22960","volume":"77","author":"A Aminian","year":"2011","unstructured":"Aminian A, Lalmand J, El Nakadi B. Perforation of the descending thoracic aorta during transcatheter aortic valve implantation (TAVI): an unexpected and dramatic procedural complication. Catheter Cardiovasc Interv. 2011;77:1076\u20138.","journal-title":"Catheter Cardiovasc Interv"},{"key":"219_CR24","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/S0379-0738(99)00112-7","volume":"105","author":"W Grellner","year":"1999","unstructured":"Grellner W. Death during percutaneous transluminal coronary angioplasty (PTCA) and the medicolegal aspects. Forensic Sci Int. 1999;105:25\u201333.","journal-title":"Forensic Sci Int"}],"updated-by":[{"DOI":"10.1007\/s12024-021-00412-x","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2021,8,4]],"date-time":"2021-08-04T00:00:00Z","timestamp":1628035200000}}],"container-title":["Forensic Science, Medicine and Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12024-020-00219-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12024-020-00219-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12024-020-00219-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,11]],"date-time":"2021-08-11T17:25:57Z","timestamp":1628702757000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12024-020-00219-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,14]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["219"],"URL":"https:\/\/doi.org\/10.1007\/s12024-020-00219-2","relation":{"correction":[{"id-type":"doi","id":"10.1007\/s12024-021-00412-x","asserted-by":"object"}]},"ISSN":["1547-769X","1556-2891"],"issn-type":[{"value":"1547-769X","type":"print"},{"value":"1556-2891","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,14]]},"assertion":[{"value":"13 January 2020","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 March 2020","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 August 2021","order":3,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":4,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":5,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s12024-021-00412-x","URL":"https:\/\/doi.org\/10.1007\/s12024-021-00412-x","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}