{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T05:10:13Z","timestamp":1789449013291,"version":"build-2803163510"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,11,28]],"date-time":"2022-11-28T00:00:00Z","timestamp":1669593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,11,28]],"date-time":"2022-11-28T00:00:00Z","timestamp":1669593600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Forensic Sci Med Pathol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This paper presents the results of a study on the applicability of cerebrospinal fluid (CSF) collected from the spinal canal in the post-mortem determination of ethyl alcohol. The present study reviewed data of autopsy cases (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200945), in which ethyl alcohol was detected in CSF using gas chromatography with a flame ionization detector (HS-GC-FID), to investigate ethyl alcohol concentrations in CSF, compared with blood. As a result of statistical analysis of the obtained data, a high positive correlation was found between blood ethanol concentration and cerebrospinal fluid collected from the spinal canal ethanol concentration. The Pearson correlation coefficient was statistically highly significant (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001) (\n                    <jats:italic>r<\/jats:italic>\n                    \u2009=\u20090.9503). The data obtained allowed us to conclude that cerebrospinal fluid collected from the spinal canal can be collected during an autopsy as an alternative biological specimen to assess the ethanol content. Cerebrospinal fluid collected from the spinal canal can corroborate and lend credibility to the results obtained for blood and, in special cases, when blood is drawn from putrefied bodies and may even be a superior specimen to blood for assessing ethyl alcohol intoxication status.\n                  <\/jats:p>","DOI":"10.1007\/s12024-022-00560-8","type":"journal-article","created":{"date-parts":[[2022,11,28]],"date-time":"2022-11-28T09:03:00Z","timestamp":1669626180000},"page":"44-49","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Assessing the applicability of cerebrospinal fluid collected from the spinal cord for the determination of ethyl alcohol in post-mortem toxicology"],"prefix":"10.1007","volume":"19","author":[{"given":"Paulina","family":"Wachholz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1445-3807","authenticated-orcid":false,"given":"Rafa\u0142","family":"Skowronek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Pawlas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,11,28]]},"reference":[{"issue":"1","key":"560_CR1","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.forsciint.2006.05.004","volume":"165","author":"FC Kugelberg","year":"2007","unstructured":"Kugelberg FC, Jones AW. Interpreting results of ethanol analysis in postmortem specimens: a review of the literature. Forensic Sci Int. 2007;165(1):10\u201329.","journal-title":"Forensic Sci Int"},{"issue":"2\u20133","key":"560_CR2","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.forsciint.2004.02.012","volume":"142","author":"G Skopp","year":"2004","unstructured":"Skopp G. Preanalytic aspects in postmortem toxicology. Forensic Sci Int. 2004;142(2\u20133):75\u2013100.","journal-title":"Forensic Sci Int"},{"key":"560_CR3","unstructured":"Polskie Towarzystwo Medycyny S\u0105dowej i Kryminologii. Zalecenia PTMSiK w sprawie pobierania materia\u0142u sekcyjnego do bada\u0144 toksykologicznych. 2012. http:\/\/www.ptmsik.pl\/pdf\/Zalecenia_PTMSiK_w_sprawie_pobierania_materialu_sekcyjnego_do_badan_toksykologicznych.pdf. Accessed 15 Nov 2021."},{"issue":"3","key":"560_CR4","first-page":"208","volume":"68","author":"R Skowronek","year":"2018","unstructured":"Skowronek R, Zawadzki M. Is it time to update the Recommendations of the Polish Society of Forensic Medicine and Criminology on the collection of post-mortem material for toxicological analysis? Arch Med Sadowej Kryminol. 2018;68(3):208\u201310.","journal-title":"Arch Med Sadowej Kryminol"},{"key":"560_CR5","unstructured":"Tomsia M, Nowicka J, Che\u0142mecka E, Wo\u015b M, W\u00f3jcik J, Dro\u017adziok K, Skowronek R. A comparative study of ethyl alcohol concentration in coastal cartlilage in relation to blood and urine. 57th Annual Meeting of the International Association of Forensic Toxicologists, Birmingham. 2019;236:Abstract ID 427."},{"key":"560_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jflm.2021.102231","volume":"82","author":"P Wachholz","year":"2021","unstructured":"Wachholz P, Skowronek R, Pawlas N. Cerebrospinal fluid in forensic toxicology: current status and future perspectives. 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Studies on the value of simultaneous determining alcohol with Widmark\u2019s method in blood and in cerebrospinal fluid after death. Arch Med Sadowej Kryminol. 1968;18:67\u201372.","journal-title":"Arch Med Sadowej Kryminol"},{"issue":"5","key":"560_CR13","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1093\/jat\/bkaa018","volume":"44","author":"G Thelander","year":"2020","unstructured":"Thelander G, Kugelberg FC, Jones AW. High correlation between ethanol concentrations in postmortem femoral blood and in alternative biological specimens, but large uncertainty when the linear regression model was used for prediction in individual cases. J Anal Toxicol. 2020;44(5):415\u201321.","journal-title":"J Anal Toxicol"},{"key":"560_CR14","unstructured":"Gelbke HP, Lesch P, Spiegelhalder B, Schmidt G. Postmortal alkoholkonzentrationen. II. 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