{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:56:35Z","timestamp":1786982195643,"version":"build-2736575974"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T00:00:00Z","timestamp":1717372800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T00:00:00Z","timestamp":1717372800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32170939 and 82371846"],"award-info":[{"award-number":["32170939 and 82371846"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Immunol Res"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1007\/s12026-024-09499-0","type":"journal-article","created":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T11:02:41Z","timestamp":1717412561000},"page":"902-907","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Analysis of binding and authentic virus-neutralizing activities of immune sera induced by various monkeypox virus antigens"],"prefix":"10.1007","volume":"72","author":[{"given":"Shuo","family":"Song","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuning","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengjun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yushan","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingxia","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongzhou","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenguang","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,3]]},"reference":[{"key":"9499_CR1","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1038\/s41577-022-00775-4","volume":"22","author":"F-M Lum","year":"2022","unstructured":"Lum F-M, et al. Monkeypox: disease epidemiology, host immunity and clinical interventions. Nat Rev Immunol. 2022;22:597\u2013613. https:\/\/doi.org\/10.1038\/s41577-022-00775-4.","journal-title":"Nat Rev Immunol"},{"key":"9499_CR2","doi-asserted-by":"publisher","first-page":"e73","DOI":"10.1016\/j.jinf.2023.07.017","volume":"87","author":"T Xu","year":"2023","unstructured":"Xu T, Zhang L. Rising prevalence of mpox in China, Japan, and Republic of Korea. J Infect. 2023;87:e73\u20134. https:\/\/doi.org\/10.1016\/j.jinf.2023.07.017.","journal-title":"J Infect"},{"key":"9499_CR3","doi-asserted-by":"publisher","first-page":"2299","DOI":"10.1056\/NEJMc2306239","volume":"389","author":"AC Kottkamp","year":"2023","unstructured":"Kottkamp AC, et al. Antibody titers against Mpox virus after vaccination. N Engl J Med. 2023;389:2299\u2013301. https:\/\/doi.org\/10.1056\/NEJMc2306239.","journal-title":"N Engl J Med"},{"key":"9499_CR4","doi-asserted-by":"publisher","first-page":"e11","DOI":"10.1016\/S1473-3099(23)00741-7","volume":"24","author":"M Bottanelli","year":"2024","unstructured":"Bottanelli M, et al. A case of breakthrough mpox infection in an individual non-responder to MVA-BN vaccination. Lancet Infect Dis. 2024;24:e11\u20132. https:\/\/doi.org\/10.1016\/S1473-3099(23)00741-7.","journal-title":"Lancet Infect Dis"},{"key":"9499_CR5","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/S1473-3099(23)00492-9","volume":"24","author":"A Hazra","year":"2024","unstructured":"Hazra A, et al. Mpox in people with past infection or a complete vaccination course: a global case series. Lancet Infect Dis. 2024;24:57\u201364. https:\/\/doi.org\/10.1016\/S1473-3099(23)00492-9.","journal-title":"Lancet Infect Dis"},{"key":"9499_CR6","doi-asserted-by":"publisher","first-page":"2963","DOI":"10.3390\/ijerph20042963","volume":"20","author":"SM Malone","year":"2023","unstructured":"Malone SM, et al. Safety and efficacy of post-eradication smallpox vaccine as an Mpox vaccine: a systematic review with meta-analysis. Int J Environ Res Public Health. 2023;20:2963.","journal-title":"Int J Environ Res Public Health"},{"key":"9499_CR7","doi-asserted-by":"publisher","first-page":"559","DOI":"10.15585\/mmwr.mm7220a4","volume":"72","author":"ES Rosenberg","year":"2023","unstructured":"Rosenberg ES, Dorabawila V, Hart-Malloy R, et al. Effectiveness of JYNNEOS vaccine against diagnosed Mpox infection \u2014 New York, 2022. MMWR Morb Mortal Wkly Rep. 2023;72:559\u201363.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"9499_CR8","doi-asserted-by":"publisher","first-page":"553","DOI":"10.15585\/mmwr.mm7220a3","volume":"72","author":"AF Dalton","year":"2023","unstructured":"Dalton AF, Diallo AO, Chard AN, et al. Estimated effectiveness of JYNNEOS vaccine in preventing Mpox: a multijurisdictional case-control study \u2014 United States, August 19, 2022\u2013March 31, 2023. MMWR Morb Mortal Wkly Rep. 2023;72:553\u20138.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"9499_CR9","doi-asserted-by":"publisher","first-page":"o2829","DOI":"10.1136\/bmj.o2829","volume":"379","author":"E Mahase","year":"2022","unstructured":"Mahase E. Monkeypox: single dose of smallpox vaccine offers 78% protection. UKHSA reports BMJ. 2022;379:o2829. https:\/\/doi.org\/10.1136\/bmj.o2829.","journal-title":"UKHSA reports BMJ"},{"key":"9499_CR10","doi-asserted-by":"publisher","first-page":"104714","DOI":"10.1016\/j.idnow.2023.104714","volume":"53","author":"S Jamard","year":"2023","unstructured":"Jamard S, et al. Resurgence of symptomatic Mpox among vaccinated patients: first clues from a new-onset local cluster. Infect Dis Now. 2023;53:104714. https:\/\/doi.org\/10.1016\/j.idnow.2023.104714.","journal-title":"Infect Dis Now"},{"key":"9499_CR11","doi-asserted-by":"publisher","first-page":"696","DOI":"10.15585\/mmwr.mm7225a6","volume":"72","author":"EA Faherty","year":"2023","unstructured":"Faherty EA, Holly T, Ogale YP, et al. Notes from the field: emergence of an Mpox cluster primarily affecting persons previously vaccinated against Mpox \u2014 Chicago, Illinois, March 18\u2013June 12, 2023. MMWR Morb Mortal Wkly Rep. 2023;72:696\u20138.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"9499_CR12","doi-asserted-by":"publisher","first-page":"109270","DOI":"10.1016\/j.cclet.2023.109270","volume":"35","author":"Y Tian","year":"2023","unstructured":"Tian Y, et al. An MPXV mRNA-LNP vaccine candidate elicits protective immune responses against monkeypox virus. Chin Chem Lett. 2023;35:109270. https:\/\/doi.org\/10.1016\/j.cclet.2023.109270.","journal-title":"Chin Chem Lett"},{"key":"9499_CR13","doi-asserted-by":"publisher","first-page":"e28983","DOI":"10.1002\/jmv.28983","volume":"95","author":"Y Jiang","year":"2023","unstructured":"Jiang Y, et al. Various mpox recombinant subunits induce broadly reactive antibodies against orthopoxvirus in mice. J Med Virol. 2023;95:e28983. https:\/\/doi.org\/10.1002\/jmv.28983.","journal-title":"J Med Virol"},{"key":"9499_CR14","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1016\/j.jinf.2022.10.036","volume":"85","author":"M Li","year":"2022","unstructured":"Li M, et al. Development of monoclonal antibody-based antigens detection assays for orthopoxvirus and monkeypox virus. J Infect. 2022;85:702\u201369. https:\/\/doi.org\/10.1016\/j.jinf.2022.10.036.","journal-title":"J Infect"},{"key":"9499_CR15","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/j.medcle.2023.01.005","volume":"160","author":"J Reina","year":"2023","unstructured":"Reina J, Iglesias C. Vaccines against monkeypox. Med Clin (Engl Ed). 2023;160:305\u20139. https:\/\/doi.org\/10.1016\/j.medcle.2023.01.005.","journal-title":"Med Clin (Engl Ed)"},{"key":"9499_CR16","doi-asserted-by":"publisher","first-page":"2223669","DOI":"10.1080\/22221751.2023.2223669","volume":"12","author":"M Li","year":"2023","unstructured":"Li M, et al. Three neutralizing mAbs induced by MPXV A29L protein recognizing different epitopes act synergistically against orthopoxvirus. Emerg Microbes Infect. 2023;12:2223669. https:\/\/doi.org\/10.1080\/22221751.2023.2223669.","journal-title":"Emerg Microbes Infect"},{"key":"9499_CR17","doi-asserted-by":"publisher","first-page":"eadg3540","DOI":"10.1126\/scitranslmed.adg3540","volume":"15","author":"AW Freyn","year":"2023","unstructured":"Freyn AW, et al. An mpox virus mRNA-lipid nanoparticle vaccine confers protection against lethal orthopoxviral challenge. Sci Transl Med. 2023;15:eadg3540. https:\/\/doi.org\/10.1126\/scitranslmed.adg3540.","journal-title":"Sci Transl Med"},{"key":"9499_CR18","doi-asserted-by":"publisher","first-page":"2204151","DOI":"10.1080\/22221751.2023.2204151","volume":"12","author":"J Zeng","year":"2023","unstructured":"Zeng J, et al. Mpox multi-antigen mRNA vaccine candidates by a simplified manufacturing strategy afford efficient protection against lethal orthopoxvirus challenge. Emerg Microbes Infect. 2023;12:2204151. https:\/\/doi.org\/10.1080\/22221751.2023.2204151.","journal-title":"Emerg Microbes Infect"},{"key":"9499_CR19","doi-asserted-by":"publisher","first-page":"2192815","DOI":"10.1080\/22221751.2023.2192815","volume":"12","author":"R-R Zhang","year":"2023","unstructured":"Zhang R-R, et al. Rational development of multicomponent mRNA vaccine candidates against mpox. Emerg Microbes Infect. 2023;12:2192815. https:\/\/doi.org\/10.1080\/22221751.2023.2192815.","journal-title":"Emerg Microbes Infect"},{"issue":"1","key":"9499_CR20","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/0042-6822(90)90381-Z","volume":"178","author":"SC Gong","year":"1990","unstructured":"Gong SC, Lai CF, Esteban M. Vaccinia virus induces cell fusion at acid pH and this activity is mediated by the N-terminus of the 14-kDa virus envelope protein. Virology. 1990;178(1):81\u201391.","journal-title":"Virology"},{"issue":"8","key":"9499_CR21","doi-asserted-by":"publisher","first-page":"e1003563","DOI":"10.1371\/journal.ppat.1003563","volume":"9","author":"TH Chang","year":"2013","unstructured":"Chang TH, Chang SJ, Hsieh FL, et al. Crystal structure of vaccinia viral A27 protein reveals a novel structure critical for its function and complex formation with A26 protein. PLoS Pathog. 2013;9(8):e1003563.","journal-title":"PLoS Pathog"},{"key":"9499_CR22","doi-asserted-by":"publisher","first-page":"3353","DOI":"10.1128\/jvi.74.7.3353-3365.2000","volume":"74","author":"C-L Lin","year":"2000","unstructured":"Lin C-L, Chung C-S, Heine Hans G, Chang W. Vaccinia virus envelope H3L protein binds to cell surface heparan sulfate and is important for intracellular mature virion morphogenesis and virus infection in vitro and in vivo. J Virol. 2000;74:3353\u201365. https:\/\/doi.org\/10.1128\/jvi.74.7.3353-3365.2000.","journal-title":"J Virol"}],"container-title":["Immunologic Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12026-024-09499-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12026-024-09499-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12026-024-09499-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,14]],"date-time":"2024-11-14T05:08:25Z","timestamp":1731560905000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12026-024-09499-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,3]]},"references-count":22,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["9499"],"URL":"https:\/\/doi.org\/10.1007\/s12026-024-09499-0","relation":{},"ISSN":["0257-277X","1559-0755"],"issn-type":[{"value":"0257-277X","type":"print"},{"value":"1559-0755","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,3]]},"assertion":[{"value":"8 March 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 May 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 June 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"All in vivo experiments were approved by the Ethics Committee of the Laboratory Animal Center of Southern Medical University, and were performed according to the guidelines of the Institutional Animal Care and Use Committee, following strict guidelines for humane endpoints.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}