{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T02:53:06Z","timestamp":1791341586898,"version":"4.3.1"},"reference-count":120,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T00:00:00Z","timestamp":1752192000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T00:00:00Z","timestamp":1752192000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Immunol Res"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1007\/s12026-025-09655-0","type":"journal-article","created":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T19:38:48Z","timestamp":1752262728000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Metabolic-associated enthesitis: a review on pathophysiology, clinical relevance, diagnostic challenges, and perspective on target treatments"],"prefix":"10.1007","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6521-8578","authenticated-orcid":false,"given":"Giuseppe","family":"Lisco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6341-6140","authenticated-orcid":false,"given":"Anna","family":"De Tullio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9885-1185","authenticated-orcid":false,"given":"Roberta","family":"Zupo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6853-3450","authenticated-orcid":false,"given":"Marcella","family":"Prete","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3221-6562","authenticated-orcid":false,"given":"Giuseppina","family":"Piazzolla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8639-1940","authenticated-orcid":false,"given":"Vito","family":"Racanelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6308-0528","authenticated-orcid":false,"given":"Vincenzo","family":"Triggiani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,11]]},"reference":[{"issue":"1","key":"9655_CR1","first-page":"35","volume":"10","author":"S Thomopoulos","year":"2010","unstructured":"Thomopoulos S, Genin GM, Galatz LM. The development and morphogenesis of the tendon-to-bone insertion - what development can teach us about healing -. J Musculoskelet Neuronal Interact. 2010M;10(1):35\u201345.","journal-title":"J Musculoskelet Neuronal Interact"},{"key":"9655_CR2","doi-asserted-by":"publisher","unstructured":"Selmi C, Gershwin ME. Diagnosis and classification of reactive arthritis. Autoimmun Rev. 2014 Apr-May;13(4\u20135):546\u20139. https:\/\/doi.org\/10.1016\/j.autrev.2014.01.005.","DOI":"10.1016\/j.autrev.2014.01.005"},{"issue":"4","key":"9655_CR3","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1097\/01.bor.0000167753.01168.bd","volume":"17","author":"PJ Healy","year":"2005","unstructured":"Healy PJ, Helliwell PS. Classification of the spondyloarthropathies. Curr Opin Rheumatol. 2005J;17(4):395\u20139. https:\/\/doi.org\/10.1097\/01.bor.0000167753.01168.bd.","journal-title":"Curr Opin Rheumatol"},{"key":"9655_CR4","doi-asserted-by":"publisher","unstructured":"Taylor W, Gladman D, Helliwell P, Marchesoni A, Mease P, Mielants H; CASPAR Study Group. Classification criteria for psoriatic arthritis: development of new criteria from a large international study. Arthritis Rheum. 2006 Aug;54(8):2665\u201373. https:\/\/doi.org\/10.1002\/art.21972.","DOI":"10.1002\/art.21972"},{"issue":"1","key":"9655_CR5","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1136\/ard-2022-223296","volume":"82","author":"S Ramiro","year":"2023","unstructured":"Ramiro S, Nikiphorou E, Sepriano A, Ortolan A, Webers C, Baraliakos X, Landew\u00e9 RBM, Van den Bosch FE, Boteva B, Bremander A, Carron P, Ciurea A, van Gaalen FA, G\u00e9her P, Gensler L, Hermann J, de Hooge M, Husakova M, Kiltz U, L\u00f3pez-Medina C, Machado PM, Marzo-Ortega H, Molto A, Navarro-Comp\u00e1n V, Nissen MJ, Pimentel-Santos FM, Poddubnyy D, Proft F, Rudwaleit M, Telkman M, Zhao SS, Ziade N, van der Heijde D. ASAS-EULAR recommendations for the management of axial spondyloarthritis: 2022 update. Ann Rheum Dis. 2023J;82(1):19\u201334. https:\/\/doi.org\/10.1136\/ard-2022-223296.","journal-title":"Ann Rheum Dis"},{"key":"9655_CR6","doi-asserted-by":"publisher","unstructured":"Rudwaleit M, van der Heijde D, Landew\u00e9 R, Listing J, Akkoc N, Brandt J, Braun J, Chou CT, Collantes-Estevez E, Dougados M, Huang F, Gu J, Khan MA, Kirazli Y, Maksymowych WP, Mielants H, S\u00f8rensen IJ, Ozgocmen S, Roussou E, Valle-O\u00f1ate R, Weber U, Wei J, Sieper J. The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection. Ann Rheum Dis. 2009 Jun;68(6):777\u201383. https:\/\/doi.org\/10.1136\/ard.2009.108233. Epub 2009 Mar 17. Erratum in: Ann Rheum Dis. 2019 Jun;78(6):e59. https:\/\/doi.org\/10.1136\/ard.2009.108233corr1.","DOI":"10.1136\/ard.2009.108233"},{"issue":"1","key":"9655_CR7","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1136\/ard.2010.133645","volume":"70","author":"M Rudwaleit","year":"2011","unstructured":"Rudwaleit M, van der Heijde D, Landew\u00e9 R, Akkoc N, Brandt J, Chou CT, Dougados M, Huang F, Gu J, Kirazli Y, Van den Bosch F, Olivieri I, Roussou E, Scarpato S, S\u00f8rensen IJ, Valle-O\u00f1ate R, Weber U, Wei J, Sieper J. The Assessment of SpondyloArthritis International Society classification criteria for peripheral spondyloarthritis and for spondyloarthritis in general. Ann Rheum Dis. 2011J;70(1):25\u201331. https:\/\/doi.org\/10.1136\/ard.2010.133645.","journal-title":"Ann Rheum Dis"},{"key":"9655_CR8","doi-asserted-by":"publisher","unstructured":"Balint PV, Terslev L, Aegerter P, Bruyn GAW, Chary-Valckenaere I, Gandjbakhch F, Iagnocco A, Jousse-Joulin S, M\u00f6ller I, Naredo E, Schmidt WA, Wakefield RJ, D'Agostino MA; OMERACT Ultrasound Task Force members. Reliability of a consensus-based ultrasound definition and scoring for enthesitis in spondyloarthritis and psoriatic arthritis: an OMERACT US initiative. Ann Rheum Dis. 2018 Dec;77(12):1730\u20131735. https:\/\/doi.org\/10.1136\/annrheumdis-2018-213609.","DOI":"10.1136\/annrheumdis-2018-213609"},{"key":"9655_CR9","doi-asserted-by":"publisher","unstructured":"McGonagle D. Imaging the joint and enthesis: insights into pathogenesis of psoriatic arthritis. Ann Rheum Dis. 2005 Mar;64 Suppl 2(Suppl 2):ii58\u201360. https:\/\/doi.org\/10.1136\/ard.2004.034264.","DOI":"10.1136\/ard.2004.034264"},{"issue":"10","key":"9655_CR10","doi-asserted-by":"publisher","first-page":"1517","DOI":"10.1007\/s10067-014-2524-3","volume":"33","author":"M Abate","year":"2014","unstructured":"Abate M, Di Carlo L, Salini V, Schiavone C. Metabolic syndrome associated to non-inflammatory Achilles enthesopathy. Clin Rheumatol. 2014;33(10):1517\u201322. https:\/\/doi.org\/10.1007\/s10067-014-2524-3.","journal-title":"Clin Rheumatol"},{"key":"9655_CR11","doi-asserted-by":"publisher","unstructured":"Falsetti P, Conticini E, Baldi C, Bardelli M, Cantarini L, Frediani B. Diffuse peripheral enthesitis in metabolic syndrome: a retrospective clinical and power Doppler ultrasound study. Reumatol Clin (Engl Ed). 2021 Feb 24:S1699\u2013258X(21)00032\u20132. English, Spanish. https:\/\/doi.org\/10.1016\/j.reuma.2020.12.005.","DOI":"10.1016\/j.reuma.2020.12.005"},{"issue":"1","key":"9655_CR12","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2024.101966","volume":"38","author":"R Sabido-Sauri","year":"2024","unstructured":"Sabido-Sauri R, Baraliakos X, Aydin SZ. Enthesopathies - mechanical, inflammatory or both? Best Pract Res Clin Rheumatol. 2024M;38(1). https:\/\/doi.org\/10.1016\/j.berh.2024.101966.","journal-title":"Best Pract Res Clin Rheumatol"},{"issue":"12","key":"9655_CR13","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1038\/nrrheum.2017.188","volume":"13","author":"G Schett","year":"2017","unstructured":"Schett G, Lories RJ, D\u2019Agostino MA, Elewaut D, Kirkham B, Soriano ER, McGonagle D. Enthesitis: from pathophysiology to treatment. Nat Rev Rheumatol. 2017N 21;13(12):731\u201341. https:\/\/doi.org\/10.1038\/nrrheum.2017.188.","journal-title":"Nat Rev Rheumatol"},{"issue":"8","key":"9655_CR14","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1002\/acr.20496","volume":"63","author":"L Eder","year":"2011","unstructured":"Eder L, Law T, Chandran V, Shanmugarajah S, Shen H, Rosen CF, Cook RJ, Gladman DD. Association between environmental factors and onset of psoriatic arthritis in patients with psoriasis. Arthritis Care Res (Hoboken). 2011A;63(8):1091\u20137. https:\/\/doi.org\/10.1002\/acr.20496.","journal-title":"Arthritis Care Res (Hoboken)"},{"issue":"Suppl 1","key":"9655_CR15","doi-asserted-by":"publisher","first-page":"i10","DOI":"10.1093\/rheumatology\/keaa039","volume":"59","author":"EG Araujo","year":"2020","unstructured":"Araujo EG, Schett G. Enthesitis in psoriatic arthritis (Part 1): pathophysiology. Rheumatology (Oxford). 2020M 1;59(Suppl 1):i10\u20134. https:\/\/doi.org\/10.1093\/rheumatology\/keaa039.","journal-title":"Rheumatology (Oxford)"},{"issue":"7","key":"9655_CR16","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1038\/nm.2817","volume":"18","author":"JP Sherlock","year":"2012","unstructured":"Sherlock JP, Joyce-Shaikh B, Turner SP, Chao CC, Sathe M, Grein J, Gorman DM, Bowman EP, McClanahan TK, Yearley JH, Eberl G, Buckley CD, Kastelein RA, Pierce RH, Laface DM, Cua DJ. IL-23 induces spondyloarthropathy by acting on ROR-\u03b3t+ CD3+CD4-CD8- entheseal resident T cells. Nat Med. 2012J 1;18(7):1069\u201376. https:\/\/doi.org\/10.1038\/nm.2817.","journal-title":"Nat Med"},{"issue":"9","key":"9655_CR17","doi-asserted-by":"publisher","first-page":"1739","DOI":"10.1136\/annrheumdis-2014-20632","volume":"74","author":"F Ciccia","year":"2015","unstructured":"Ciccia F, Guggino G, Rizzo A, Saieva L, Peralta S, Giardina A, Cannizzaro A, Sireci G, De Leo G, Alessandro R, Triolo G. Type 3 innate lymphoid cells producing IL-17 and IL-22 are expanded in the gut, in the peripheral blood, synovial fluid and bone marrow of patients with ankylosing spondylitis. Ann Rheum Dis. 2015S;74(9):1739\u201347. https:\/\/doi.org\/10.1136\/annrheumdis-2014-20632.","journal-title":"Ann Rheum Dis"},{"issue":"2","key":"9655_CR18","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1084\/jem.20070906","volume":"205","author":"M Armaka","year":"2008","unstructured":"Armaka M, Apostolaki M, Jacques P, Kontoyiannis DL, Elewaut D, Kollias G. Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases. J Exp Med. 2008F 18;205(2):331\u20137. https:\/\/doi.org\/10.1084\/jem.20070906.","journal-title":"J Exp Med"},{"issue":"1","key":"9655_CR19","doi-asserted-by":"publisher","first-page":"4613","DOI":"10.1038\/s41467-018-06933-4","volume":"9","author":"I Cambr\u00e9","year":"2018","unstructured":"Cambr\u00e9 I, Gaublomme D, Burssens A, Jacques P, Schryvers N, De Muynck A, Meuris L, Lambrecht S, Carter S, de Bleser P, Saeys Y, Van Hoorebeke L, Kollias G, Mack M, Simoens P, Lories R, Callewaert N, Schett G, Elewaut D. Mechanical strain determines the site-specific localization of inflammation and tissue damage in arthritis. Nat Commun. 2018N 5;9(1):4613. https:\/\/doi.org\/10.1038\/s41467-018-06933-4.","journal-title":"Nat Commun"},{"issue":"2","key":"9655_CR20","doi-asserted-by":"publisher","first-page":"792","DOI":"10.3390\/ijms23020792","volume":"23","author":"J Korbecki","year":"2022","unstructured":"Korbecki J, Barczak K, Gutowska I, Chlubek D, Baranowska-Bosiacka I. CXCL1: gene, promoter, regulation of expression, mRNA stability, regulation of activity in the intercellular space. Int J Mol Sci. 2022J 12;23(2):792. https:\/\/doi.org\/10.3390\/ijms23020792.","journal-title":"Int J Mol Sci"},{"issue":"1","key":"9655_CR21","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1002\/jnr.20612","volume":"82","author":"X Qin","year":"2005","unstructured":"Qin X, Wan Y, Wang X. CCL2 and CXCL1 trigger calcitonin gene-related peptide release by exciting primary nociceptive neurons. J Neurosci Res. 2005O 1;82(1):51\u201362. https:\/\/doi.org\/10.1002\/jnr.20612.","journal-title":"J Neurosci Res"},{"issue":"1","key":"9655_CR22","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1016\/0006-291x(85)90611-4","volume":"126","author":"Y Hakeda","year":"1985","unstructured":"Hakeda Y, Nakatani Y, Kurihara N, Ikeda E, Maeda N, Kumegawa M. Prostaglandin E2 stimulates collagen and non-collagen protein synthesis and prolyl hydroxylase activity in osteoblastic clone MC3T3-E1 cells. Biochem Biophys Res Commun. 1985J 16;126(1):340\u20135. https:\/\/doi.org\/10.1016\/0006-291x(85)90611-4.","journal-title":"Biochem Biophys Res Commun"},{"issue":"10","key":"9655_CR23","doi-asserted-by":"publisher","first-page":"1332","DOI":"10.1038\/cdd.2009.74","volume":"16","author":"H Huang","year":"2009","unstructured":"Huang H, Kim HJ, Chang EJ, Lee ZH, Hwang SJ, Kim HM, Lee Y, Kim HH. IL-17 stimulates the proliferation and differentiation of human mesenchymal stem cells: implications for bone remodeling. Cell Death Differ. 2009O;16(10):1332\u201343. https:\/\/doi.org\/10.1038\/cdd.2009.74.","journal-title":"Cell Death Differ"},{"issue":"14","key":"9655_CR24","doi-asserted-by":"publisher","first-page":"3959","DOI":"10.1177\/03635465211049219","volume":"49","author":"SM Bolam","year":"2021","unstructured":"Bolam SM, Park YE, Konar S, Callon KE, Workman J, Monk AP, Coleman B, Cornish J, Vickers MH, Munro JT, Musson DS. Obesity impairs enthesis healing after rotator cuff repair in a rat model. Am J Sports Med. 2021D;49(14):3959\u201369. https:\/\/doi.org\/10.1177\/03635465211049219.","journal-title":"Am J Sports Med"},{"issue":"13","key":"9655_CR25","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.945513","volume":"2","author":"JP Sanabria-Mazo","year":"2022","unstructured":"Sanabria-Mazo JP, Colomer-Carbonell A, Carmona-Cervell\u00f3 M, Feliu-Soler A, Borr\u00e0s X, Grasa M, Esteve M, Maes M, Edo S, Sanz A, Luciano JV. Immune-inflammatory and hypothalamic-pituitary-adrenal axis biomarkers are altered in patients with non-specific low back pain: a systematic review. Front Immunol. 2022S;2(13). https:\/\/doi.org\/10.3389\/fimmu.2022.945513.","journal-title":"Front Immunol"},{"issue":"8","key":"9655_CR26","doi-asserted-by":"publisher","first-page":"1660","DOI":"10.1016\/j.clnu.2022.06.021","volume":"41","author":"I Castela","year":"2022","unstructured":"Castela I, Rodrigues C, Ismael S, Barreiros-Mota I, Morais J, Ara\u00fajo JR, Marques C, Silvestre MP, \u00c2ngelo-Dias M, Martins C, Borrego LM, Monteiro R, Coutinho SR, Calhau C, Faria A, Pestana D, Martins C, Teixeira D. Intermittent energy restriction ameliorates adipose tissue-associated inflammation in adults with obesity: a randomised controlled trial. Clin Nutr. 2022A;41(8):1660\u20136. https:\/\/doi.org\/10.1016\/j.clnu.2022.06.021.","journal-title":"Clin Nutr"},{"issue":"12","key":"9655_CR27","doi-asserted-by":"publisher","first-page":"5224","DOI":"10.1007\/s11695-021-05702-5","volume":"31","author":"ART de Sousa","year":"2021","unstructured":"de Sousa ART, Freitas Junior WR, Perez EA, Ilias EJ, Silva AS, Alves VLS, Afonso JPR, Oliveira MC, Fonseca AL, da Silva MM, Lino MEM, Oliveira Junior MC, Vieira RP, Pedro WJS, Bachi ALL, Insalaco G, Malheiros CA, Oliveira LVF. Surgery for obesity and weight-related diseases changes the inflammatory profile in women with severe obesity: a randomized controlled clinical trial. Obes Surg. 2021D;31(12):5224\u201336. https:\/\/doi.org\/10.1007\/s11695-021-05702-5.","journal-title":"Obes Surg"},{"issue":"1","key":"9655_CR28","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1186\/s13075-023-03105-8","volume":"25","author":"AJ Landgren","year":"2023","unstructured":"Landgren AJ, Jonsson CA, Bilberg A, Eliasson B, Torres L, Dehlin M, Jacobsson LTH, Gjertsson I, Larsson I, Klingberg E. Serum IL-23 significantly decreased in obese patients with psoriatic arthritis six months after a structured weight loss intervention. Arthritis Res Ther. 2023J 27;25(1):131. https:\/\/doi.org\/10.1186\/s13075-023-03105-8.","journal-title":"Arthritis Res Ther"},{"issue":"8","key":"9655_CR29","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1038\/nri3269","volume":"12","author":"K Ray","year":"2012","unstructured":"Ray K. Inflammation: IL-23 tees off enthesitis. Nat Rev Immunol. 2012J 25;12(8):552\u20133. https:\/\/doi.org\/10.1038\/nri3269.","journal-title":"Nat Rev Immunol"},{"issue":"1","key":"9655_CR30","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1111\/imr.12840","volume":"294","author":"C Bridgewood","year":"2020","unstructured":"Bridgewood C, Sharif K, Sherlock J, Watad A, McGonagle D. Interleukin-23 pathway at the enthesis: the emerging story of enthesitis in spondyloarthropathy. Immunol Rev. 2020M;294(1):27\u201347. https:\/\/doi.org\/10.1111\/imr.12840.","journal-title":"Immunol Rev"},{"issue":"5","key":"9655_CR31","doi-asserted-by":"publisher","first-page":"2475","DOI":"10.3390\/ijms25052475","volume":"25","author":"V Lambadiari","year":"2024","unstructured":"Lambadiari V, Katsimbri P, Kountouri A, Korakas E, Papathanasi A, Maratou E, Pavlidis G, Pliouta L, Ikonomidis I, Malisova S, Vlachos D, Papadavid E. The effect of a ketogenic diet versus mediterranean diet on clinical and biochemical markers of inflammation in patients with obesity and psoriatic arthritis: a randomized crossover trial. Int J Mol Sci. 2024F 20;25(5):2475. https:\/\/doi.org\/10.3390\/ijms25052475.","journal-title":"Int J Mol Sci"},{"key":"9655_CR32","doi-asserted-by":"publisher","unstructured":"GBD 2019 Risk Factors Collaborators. Global burden of 87 risk factors in 204 countries and territories, 1990\u20132019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020 Oct 17;396(10258):1223\u20131249. https:\/\/doi.org\/10.1016\/S0140-6736(20)30752-2.","DOI":"10.1016\/S0140-6736(20)30752-2"},{"issue":"6","key":"9655_CR33","doi-asserted-by":"publisher","first-page":"2403","DOI":"10.1016\/j.apsb.2023.01.012","volume":"13","author":"X Jin","year":"2023","unstructured":"Jin X, Qiu T, Li L, Yu R, Chen X, Li C, Proud CG, Jiang T. Pathophysiology of obesity and its associated diseases. Acta Pharm Sin B. 2023J;13(6):2403\u201324. https:\/\/doi.org\/10.1016\/j.apsb.2023.01.012.","journal-title":"Acta Pharm Sin B"},{"issue":"3","key":"9655_CR34","doi-asserted-by":"publisher","first-page":"466","DOI":"10.3899\/jrheum.130949","volume":"41","author":"L Eder","year":"2014","unstructured":"Eder L, Jayakar J, Thavaneswaran A, Haddad A, Chandran V, Salonen D, Rosen CF, Gladman DD. Is the MAdrid Sonographic Enthesitis Index useful for differentiating psoriatic arthritis from psoriasis alone and healthy controls? J Rheumatol. 2014M;41(3):466\u201372. https:\/\/doi.org\/10.3899\/jrheum.130949. Epub 2014 Feb 1 PMID: 24488414.","journal-title":"J Rheumatol"},{"issue":"5","key":"9655_CR35","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1136\/annrheumdis-2013-204448","volume":"74","author":"L Eder","year":"2015","unstructured":"Eder L, Thavaneswaran A, Chandran V, Cook RJ, Gladman DD. Obesity is associated with a lower probability of achieving sustained minimal disease activity state among patients with psoriatic arthritis. Ann Rheum Dis. 2015M;74(5):813\u20137. https:\/\/doi.org\/10.1136\/annrheumdis-2013-204448.","journal-title":"Ann Rheum Dis"},{"issue":"5","key":"9655_CR36","doi-asserted-by":"publisher","first-page":"937","DOI":"10.3899\/jrheum.151208","volume":"43","author":"B Makay","year":"2016","unstructured":"Makay B, G\u00fccenmez \u00d6A, \u00dcnsal E. Inactive disease in enthesitis-related arthritis: association of increased body mass index. J Rheumatol. 2016M;43(5):937\u201343. https:\/\/doi.org\/10.3899\/jrheum.151208.","journal-title":"J Rheumatol"},{"issue":"3","key":"9655_CR37","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2023-003157","volume":"9","author":"YY Leung","year":"2023","unstructured":"Leung YY, Eder L, Orbai AM, Coates LC, de Wit M, Smolen JS, Kiltz U, Palominos P, Canete JD, Scrivo R, Balanescu A, Dernis E, Meisalu S, Soubrier M, Kalyoncu U, Gossec L. Association between obesity and likelihood of remission or low disease activity status in psoriatic arthritis applying index-based and patient-based definitions of remission: a cross-sectional study. RMD Open. 2023S;9(3). https:\/\/doi.org\/10.1136\/rmdopen-2023-003157.","journal-title":"RMD Open"},{"key":"9655_CR38","doi-asserted-by":"publisher","unstructured":"Micheroli R, Hebeisen M, Wildi LM, Exer P, Tamborrini G, Bernhard J, M\u00f6ller B, Zufferey P, Nissen MJ, Scherer A, Ciurea A; Rheumatologists of the Swiss Clinical Quality Management Program. Impact of obesity on the response to tumor necrosis factor inhibitors in axial spondyloarthritis. Arthritis Res Ther. 2017 Jul 19;19(1):164. https:\/\/doi.org\/10.1186\/s13075-017-1372-3.","DOI":"10.1186\/s13075-017-1372-3"},{"issue":"1","key":"9655_CR39","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/s13075-019-1810-5","volume":"21","author":"E Klingberg","year":"2019","unstructured":"Klingberg E, Bilberg A, Bj\u00f6rkman S, Hedberg M, Jacobsson L, Forsblad-d\u2019Elia H, Carlsten H, Eliasson B, Larsson I. Weight loss improves disease activity in patients with psoriatic arthritis and obesity: an interventional study. Arthritis Res Ther. 2019J 11;21(1):17. https:\/\/doi.org\/10.1186\/s13075-019-1810-5.","journal-title":"Arthritis Res Ther"},{"issue":"1","key":"9655_CR40","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1186\/s13075-020-02350-5","volume":"22","author":"E Klingberg","year":"2020","unstructured":"Klingberg E, Bj\u00f6rkman S, Eliasson B, Larsson I, Bilberg A. Weight loss is associated with sustained improvement of disease activity and cardiovascular risk factors in patients with psoriatic arthritis and obesity: a prospective intervention study with two years of follow-up. Arthritis Res Ther. 2020O 22;22(1):254. https:\/\/doi.org\/10.1186\/s13075-020-02350-5.","journal-title":"Arthritis Res Ther"},{"issue":"2","key":"9655_CR41","doi-asserted-by":"publisher","first-page":"99","DOI":"10.7547\/16-059","volume":"107","author":"F Ursini","year":"2017","unstructured":"Ursini F, Arturi F, D\u2019Angelo S, Amara L, Nicolosi K, Russo E, Naty S, Bruno C, De Sarro G, Olivieri I, Grembiale RD. High prevalence of Achilles tendon enthesopathic changes in patients with type 2 diabetes without peripheral neuropathy. J Am Podiatr Med Assoc. 2017M;107(2):99\u2013105. https:\/\/doi.org\/10.7547\/16-059.","journal-title":"J Am Podiatr Med Assoc"},{"issue":"3","key":"9655_CR42","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0174529","volume":"12","author":"F Ursini","year":"2017","unstructured":"Ursini F, Arturi F, Nicolosi K, Ammendolia A, D\u2019Angelo S, Russo E, Naty S, Bruno C, De Sarro G, Olivieri I, Grembiale RD. Plantar fascia enthesopathy is highly prevalent in diabetic patients without peripheral neuropathy and correlates with retinopathy and impaired kidney function. PLoS ONE. 2017M 30;12(3). https:\/\/doi.org\/10.1371\/journal.pone.0174529.","journal-title":"PLoS ONE"},{"issue":"1","key":"9655_CR43","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1177\/1071100713510496","volume":"35","author":"M Abate","year":"2014","unstructured":"Abate M, Salini V, Antinolfi P, Schiavone C. Ultrasound morphology of the Achilles in asymptomatic patients with and without diabetes. Foot Ankle Int. 2014J;35(1):44\u20139. https:\/\/doi.org\/10.1177\/1071100713510496.","journal-title":"Foot Ankle Int"},{"issue":"1","key":"9655_CR44","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1177\/19322968221100842","volume":"17","author":"R Vaidya","year":"2023","unstructured":"Vaidya R, Lake SP, Zellers JA. Effect of diabetes on tendon structure and function: not limited to collagen crosslinking. J Diabetes Sci Technol. 2023J;17(1):89\u201398. https:\/\/doi.org\/10.1177\/19322968221100842.","journal-title":"J Diabetes Sci Technol"},{"key":"9655_CR45","doi-asserted-by":"publisher","unstructured":"Okur SC, Dogan YP, Mert M, Aksu O, Burnaz O, Caglar NS. Ultrasonographic evaluation of lower extremity entheseal sites in diabetic patients using Glasgow Ultrasound Enthesitis Scoring System Score. J Med Ultrasound. 2017 Jul-Sep;25(3):150\u2013156. https:\/\/doi.org\/10.1016\/j.jmu.2017.03.011.","DOI":"10.1016\/j.jmu.2017.03.011"},{"issue":"11","key":"9655_CR46","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1038\/nrendo.2017.90","volume":"13","author":"SM Reilly","year":"2017","unstructured":"Reilly SM, Saltiel AR. Adapting to obesity with adipose tissue inflammation. Nat Rev Endocrinol. 2017N;13(11):633\u201343. https:\/\/doi.org\/10.1038\/nrendo.2017.90.","journal-title":"Nat Rev Endocrinol"},{"issue":"3","key":"9655_CR47","doi-asserted-by":"publisher","first-page":"C375","DOI":"10.1152\/ajpcell.00379.2020","volume":"320","author":"T Kawai","year":"2021","unstructured":"Kawai T, Autieri MV, Scalia R. Adipose tissue inflammation and metabolic dysfunction in obesity. Am J Physiol Cell Physiol. 2021M 1;320(3):C375\u201391. https:\/\/doi.org\/10.1152\/ajpcell.00379.2020.","journal-title":"Am J Physiol Cell Physiol"},{"issue":"1","key":"9655_CR48","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1080\/21623945.2017.1402151","volume":"7","author":"G Fr\u00fchbeck","year":"2018","unstructured":"Fr\u00fchbeck G, Catal\u00e1n V, Rodr\u00edguez A, G\u00f3mez-Ambrosi J. Adiponectin-leptin ratio: a promising index to estimate adipose tissue dysfunction. Relation with obesity-associated cardiometabolic risk Adipocyte. 2018J 2;7(1):57\u201362. https:\/\/doi.org\/10.1080\/21623945.2017.1402151.","journal-title":"Relation with obesity-associated cardiometabolic risk Adipocyte"},{"issue":"1","key":"9655_CR49","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1002\/jbmr.1734","volume":"28","author":"RT Turner","year":"2013","unstructured":"Turner RT, Kalra SP, Wong CP, Philbrick KA, Lindenmaier LB, Boghossian S, Iwaniec UT. Peripheral leptin regulates bone formation. J Bone Miner Res. 2013J;28(1):22\u201334. https:\/\/doi.org\/10.1002\/jbmr.1734.","journal-title":"J Bone Miner Res"},{"key":"9655_CR50","doi-asserted-by":"publisher","first-page":"5481","DOI":"10.2174\/092986712803833146","volume":"19","author":"I Kanazawa","year":"2012","unstructured":"Kanazawa I. Adiponectin in metabolic bone disease. Curr Med Chem. 2012;19:5481\u201392.","journal-title":"Curr Med Chem"},{"key":"9655_CR51","unstructured":"Miranda-Filloy JA, L\u00f3pez-Mejias R, Genre F, Carnero-L\u00f3pez B, Ochoa R, Diaz de Ter\u00e1n T, Gonz\u00e1lez-Juanatey C, Blanco R, Llorca J, Gonz\u00e1lez-Gay MA. Adiponectin and resistin serum levels in non-diabetic ankylosing spondylitis patients undergoing TNF-\u03b1 antagonist therapy. Clin Exp Rheumatol. 2013 May-Jun;31(3):365\u201371."},{"issue":"2","key":"9655_CR52","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1677\/JOE-06-0047.Erratum.In:JEndocrinol.2007Mar;192(3):683","volume":"192","author":"PJ Simons","year":"2007","unstructured":"Simons PJ, van den Pangaart PS, Aerts JM, Boon L. Proinflammatory delipidizing cytokines reduce adiponectin secretion from human adipocytes without affecting adiponectin oligomerization. J Endocrinol. 2007F;192(2):289\u201399. https:\/\/doi.org\/10.1677\/JOE-06-0047.Erratum.In:JEndocrinol.2007Mar;192(3):683.","journal-title":"J Endocrinol"},{"issue":"3","key":"9655_CR53","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1080\/07853890.2016.1243802","volume":"49","author":"A Neve","year":"2017","unstructured":"Neve A, Maruotti N, Corrado A, Cantatore FP. Pathogenesis of ligaments ossification in spondyloarthritis: insights and doubts. Ann Med. 2017M;49(3):196\u2013205. https:\/\/doi.org\/10.1080\/07853890.2016.1243802.","journal-title":"Ann Med"},{"issue":"3","key":"9655_CR54","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1136\/annrheumdis-2011-200372","volume":"71","author":"W Hui","year":"2012","unstructured":"Hui W, Litherland GJ, Elias MS, Kitson GI, Cawston TE, Rowan AD, Young DA. Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases. Ann Rheum Dis. 2012M;71(3):455\u201362. https:\/\/doi.org\/10.1136\/annrheumdis-2011-200372.","journal-title":"Ann Rheum Dis"},{"issue":"10","key":"9655_CR55","doi-asserted-by":"publisher","first-page":"2959","DOI":"10.3390\/jcm13102959","volume":"13","author":"E Toledano","year":"2024","unstructured":"Toledano E, G\u00f3mez-Lech\u00f3n L, Chac\u00f3n CC, Hidalgo C, Ib\u00e1\u00f1ez M, M\u00e1rquez A, Queiro R, Montilla C. Clinical features and disease activity in psoriatic arthritis: a sex-related perspective on leptin and comorbidity. J Clin Med. 2024M 17;13(10):2959. https:\/\/doi.org\/10.3390\/jcm13102959.","journal-title":"J Clin Med"},{"issue":"8","key":"9655_CR56","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.711875","volume":"22","author":"A Zabotti","year":"2021","unstructured":"Zabotti A, Luchetti MM, Selmi CF, Ramonda R, Grembiale RD, Dagna L, D\u2019Angelo S, Cafaro G, De Vita S, Felicetti M, Marelli S, Frigerio D, Favalli EG. An Italian disease-based registry of axial and peripheral spondyloarthritis: the SIRENA study. Front Med (Lausanne). 2021S;22(8). https:\/\/doi.org\/10.3389\/fmed.2021.711875.","journal-title":"Front Med (Lausanne)"},{"key":"9655_CR57","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/631408","volume":"2013","author":"R Peluso","year":"2013","unstructured":"Peluso R, Di Minno MN, Iervolino S, Manguso F, Tramontano G, Ambrosino P, Esposito C, Scalera A, Castiglione F, Scarpa R. Enteropathic spondyloarthritis: from diagnosis to treatment. Clin Dev Immunol. 2013;2013. https:\/\/doi.org\/10.1155\/2013\/631408.","journal-title":"Clin Dev Immunol"},{"issue":"2","key":"9655_CR58","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1002\/art.39458","volume":"68","author":"AS Kehl","year":"2016","unstructured":"Kehl AS, Corr M, Weisman MH. Review: enthesitis: new insights into pathogenesis, diagnostic modalities, and treatment. Arthritis Rheumatol. 2016F;68(2):312\u201322. https:\/\/doi.org\/10.1002\/art.39458.","journal-title":"Arthritis Rheumatol"},{"key":"9655_CR59","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2021.12.012","volume":"52","author":"AJ Mathew","year":"2022","unstructured":"Mathew AJ, Glintborg B, Krogh NS, Hetland ML, \u00d8stergaard M. Enthesitis in patients with psoriatic arthritis and axial spondyloarthritis - data from the Danish nationwide DANBIO registry. Semin Arthritis Rheum. 2022F;52. https:\/\/doi.org\/10.1016\/j.semarthrit.2021.12.012.","journal-title":"Semin Arthritis Rheum"},{"issue":"11","key":"9655_CR60","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.1002\/acr.23174","volume":"69","author":"A Polachek","year":"2017","unstructured":"Polachek A, Li S, Chandran V, Gladman DD. Clinical enthesitis in a prospective longitudinal psoriatic arthritis cohort: incidence, prevalence, characteristics, and outcome. Arthritis Care Res (Hoboken). 2017N;69(11):1685\u201391. https:\/\/doi.org\/10.1002\/acr.23174.","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"9655_CR61","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2022.108893","volume":"110","author":"J Wu","year":"2022","unstructured":"Wu J, Hu J, Zhang F, Jin Q, Sun X. High glucose promotes IL-17A-induced gene expression through histone acetylation in retinal pigment epithelium cells. Int Immunopharmacol. 2022S;110. https:\/\/doi.org\/10.1016\/j.intimp.2022.108893.","journal-title":"Int Immunopharmacol"},{"issue":"16","key":"9655_CR62","doi-asserted-by":"publisher","first-page":"1885","DOI":"10.2147\/DMSO.S405374","volume":"23","author":"A Di Vincenzo","year":"2023","unstructured":"Di Vincenzo A, Granzotto M, Crescenzi M, Costa C, Piaserico S, Vindigni V, Vettor R, Rossato M. Insulin stimulates IL-23 expression in human adipocytes: a possible explanation for the higher prevalence of psoriasis in obesity. Diabetes Metab Syndr Obes. 2023J;23(16):1885\u201393. https:\/\/doi.org\/10.2147\/DMSO.S405374.","journal-title":"Diabetes Metab Syndr Obes"},{"issue":"10","key":"9655_CR63","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1002\/acr2.11488","volume":"4","author":"T Falasinnu","year":"2022","unstructured":"Falasinnu T, Nguyen T, Jiang TE, Chaichian Y, Rector A, Darnall BD, Mackey S, Simard JF. The problem of pain in rheumatology: clinical profiles associated with concomitant diagnoses with chronic overlapping pain conditions. ACR Open Rheumatol. 2022O;4(10):890\u20136. https:\/\/doi.org\/10.1002\/acr2.11488.","journal-title":"ACR Open Rheumatol"},{"issue":"7","key":"9655_CR64","doi-asserted-by":"publisher","first-page":"141","DOI":"10.3389\/fmed.2020.00141","volume":"7","author":"G Sakellariou","year":"2020","unstructured":"Sakellariou G, Scir\u00e8 CA, Adinolfi A, Batticciotto A, Bortoluzzi A, Delle Sedie A, De Lucia O, Dejaco C, Epis OM, Filippucci E, Idolazzi L, Picchianti Diamanti A, Zabotti A, Iagnocco A, Filippou G. Differential diagnosis of inflammatory arthropathies by musculoskeletal ultrasonography: a systematic literature review. Front Med (Lausanne). 2020M;7(7):141. https:\/\/doi.org\/10.3389\/fmed.2020.00141.","journal-title":"Front Med (Lausanne)"},{"issue":"11","key":"9655_CR65","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1136\/annrheumdis-2021-220478","volume":"80","author":"E Filippucci","year":"2021","unstructured":"Filippucci E, Smerilli G, Di Matteo A, Grassi W. Ultrasound definition of enthesitis in spondyloarthritis and psoriatic arthritis: arrival or starting point? Ann Rheum Dis. 2021N;80(11):1373\u20135. https:\/\/doi.org\/10.1136\/annrheumdis-2021-220478.","journal-title":"Ann Rheum Dis"},{"issue":"2","key":"9655_CR66","doi-asserted-by":"publisher","first-page":"162","DOI":"10.7555\/JBR.31.20160088","volume":"31","author":"H Zhang","year":"2017","unstructured":"Zhang H, Liang J, Qiu J, Wang F, Sun L. Ultrasonographic evaluation of enthesitis in patients with ankylosing spondylitis. J Biomed Res. 2017J 19;31(2):162\u20139. https:\/\/doi.org\/10.7555\/JBR.31.20160088.","journal-title":"J Biomed Res"},{"key":"9655_CR67","doi-asserted-by":"publisher","unstructured":"Coates LC, Soriano ER, Corp N, Bertheussen H, Callis Duffin K, Campanholo CB, Chau J, Eder L, Fern\u00e1ndez-\u00c1vila DG, FitzGerald O, Garg A, Gladman DD, Goel N, Helliwell PS, Husni ME, Jadon DR, Katz A, Laheru D, Latella J, Leung YY, Lindsay C, Lubrano E, Mazzuoccolo LD, Mease PJ, O'Sullivan D, Ogdie A, Olsder W, Palominos PE, Schick L, Steinkoenig I, de Wit M, van der Windt DA, Kavanaugh A; GRAPPA Treatment Recommendations domain subcommittees. Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA): updated treatment recommendations for psoriatic arthritis 2021. Nat Rev Rheumatol. 2022 Aug;18(8):465\u2013479. https:\/\/doi.org\/10.1038\/s41584-022-00798-0. Epub 2022 Jun 27. Erratum in: Nat Rev Rheumatol. 2022 Dec;18(12):734. https:\/\/doi.org\/10.1038\/s41584-022-00861-w.","DOI":"10.1038\/s41584-022-00798-0"},{"key":"9655_CR68","doi-asserted-by":"publisher","unstructured":"Yumuk V, Tsigos C, Fried M, Schindler K, Busetto L, Micic D, Toplak H; Obesity Management Task Force of the European Association for the Study of Obesity. European Guidelines for Obesity Management in Adults. Obes Facts. 2015;8(6):402\u201324. https:\/\/doi.org\/10.1159\/000442721. Epub 2015 Dec 5. Erratum in: Obes Facts. 2016;9(1):64. https:\/\/doi.org\/10.1159\/000444869.","DOI":"10.1159\/000442721"},{"issue":"5","key":"9655_CR69","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.5114\/aoms\/152921","volume":"18","author":"P Dobrowolski","year":"2022","unstructured":"Dobrowolski P, Prejbisz A, Kury\u0142owicz A, Baska A, Burchardt P, Chlebus K, Dzida G, Jankowski P, Jaroszewicz J, Jaworski P, Kami\u0144ski K, Kap\u0142on-Cie\u015blicka A, Klocek M, Kukla M, Mamcarz A, Mastalerz-Migas A, Narkiewicz K, Ostrowska L, \u015ali\u017c D, Tarnowski W, Wolf J, Wyle\u017co\u0142 M, Zdrojewski T, Banach M, Januszewicz A, Bogda\u0144ski P. Metabolic syndrome - a new definition and management guidelines: a joint position paper by the Polish Society of Hypertension, Polish Society for the Treatment of Obesity, Polish Lipid Association, Polish Association for Study of Liver, Polish Society of Family Medicine, Polish Society of Lifestyle Medicine, Division of Prevention and Epidemiology Polish Cardiac Society, \u201cClub 30\u201d Polish Cardiac Society, and Division of Metabolic and Bariatric Surgery Society of Polish Surgeons. Arch Med Sci. 2022A 30;18(5):1133\u201356. https:\/\/doi.org\/10.5114\/aoms\/152921.","journal-title":"Arch Med Sci"},{"key":"9655_CR70","doi-asserted-by":"publisher","unstructured":"American Diabetes Association Professional Practice Committee. 8. Obesity and Weight Management for the Prevention and Treatment of Type 2 Diabetes: Standards of Care in Diabetes-2024. Diabetes Care. 2024 Jan 1;47(Suppl 1):S145-S157. https:\/\/doi.org\/10.2337\/dc24-S008.","DOI":"10.2337\/dc24-S008"},{"key":"9655_CR71","doi-asserted-by":"publisher","unstructured":"DeFronzo RA, Goodman AM. Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus. The Multicenter Metformin Study Group. N Engl J Med. 1995 Aug 31;333(9):541\u20139. https:\/\/doi.org\/10.1056\/NEJM199508313330902.","DOI":"10.1056\/NEJM199508313330902"},{"key":"9655_CR72","doi-asserted-by":"publisher","DOI":"10.1111\/dom.15756","author":"JR Petrie","year":"2024","unstructured":"Petrie JR. Metformin beyond type 2 diabetes: emerging and potential new indications. Diabetes Obes Metab. 2024J 4. https:\/\/doi.org\/10.1111\/dom.15756.","journal-title":"Diabetes Obes Metab"},{"issue":"9","key":"9655_CR73","doi-asserted-by":"publisher","first-page":"1577","DOI":"10.1007\/s00125-017-4342-z","volume":"60","author":"G Rena","year":"2017","unstructured":"Rena G, Hardie DG, Pearson ER. The mechanisms of action of metformin. Diabetologia. 2017S;60(9):1577\u201385. https:\/\/doi.org\/10.1007\/s00125-017-4342-z.","journal-title":"Diabetologia"},{"issue":"8","key":"9655_CR74","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1038\/s41574-023-00833-4","volume":"19","author":"M Foretz","year":"2023","unstructured":"Foretz M, Guigas B, Viollet B. Metformin: update on mechanisms of action and repurposing potential. Nat Rev Endocrinol. 2023A;19(8):460\u201376. https:\/\/doi.org\/10.1038\/s41574-023-00833-4.","journal-title":"Nat Rev Endocrinol"},{"issue":"8","key":"9655_CR75","doi-asserted-by":"publisher","first-page":"1113","DOI":"10.1016\/j.imbio.2013.03.002","volume":"218","author":"M Sumarac-Dumanovic","year":"2013","unstructured":"Sumarac-Dumanovic M, Jeremic D, Pantovic A, Janjetovic K, Stamenkovic-Pejkovic D, Cvijovic G, Stevanovic D, Micic D, Trajkovic V. Therapeutic improvement of glucoregulation in newly diagnosed type 2 diabetes patients is associated with a reduction of IL-17 levels. Immunobiology. 2013A;218(8):1113\u20138. https:\/\/doi.org\/10.1016\/j.imbio.2013.03.002.","journal-title":"Immunobiology"},{"issue":"6","key":"9655_CR76","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1177\/1708538118777657","volume":"26","author":"SK Wang","year":"2018","unstructured":"Wang SK, Green LA, Gutwein AR, Kenyon B, Motaganahalli RL, Fajardo A, Gupta AK, Murphy MP. Metformin does not reduce inflammation in diabetics with abdominal aortic aneurysm or at high risk of abdominal aortic aneurysm formation. Vascular. 2018D;26(6):608\u201314. https:\/\/doi.org\/10.1177\/1708538118777657.","journal-title":"Vascular"},{"key":"9655_CR77","doi-asserted-by":"crossref","unstructured":"Wang L, Wang Y, Zhang P, Song C, Pan F, Li G, Peng L, Yang Y, Wei Z, Huang F. Gut microbiota changes in patients with spondyloarthritis: a systematic review. Semin Arthritis Rheum. 2022F;52.","DOI":"10.1016\/j.semarthrit.2021.11.002"},{"issue":"4","key":"9655_CR78","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1097\/BOR.0000000000000187.PMID:26002022;PMCID:PMC4489849","volume":"27","author":"T Gill","year":"2015","unstructured":"Gill T, Asquith M, Rosenbaum JT, Colbert RA. The intestinal microbiome in spondyloarthritis. Curr Opin Rheumatol. 2015J;27(4):319\u201325. https:\/\/doi.org\/10.1097\/BOR.0000000000000187.PMID:26002022;PMCID:PMC4489849.","journal-title":"Curr Opin Rheumatol"},{"key":"9655_CR79","doi-asserted-by":"crossref","unstructured":"Mauro D, Nakamura A, Haroon N, Ciccia F. The gut-enthesis axis and the pathogenesis of Spondyloarthritis. Semin Immunol. 2021D;58.","DOI":"10.1016\/j.smim.2022.101607"},{"key":"9655_CR80","doi-asserted-by":"publisher","unstructured":"Wang W, Chen L, Zhou R, Wang X, Song L, Huang S, Wang G, Xia B. Increased proportions of Bifidobacterium and the Lactobacillus group and loss of butyrate-producing bacteria in inflammatory bowel disease. J Clin Microbiol. 2014;52(2):398\u2013406. https:\/\/doi.org\/10.1128\/JCM.01500-13.","DOI":"10.1128\/JCM.01500-13"},{"issue":"6","key":"9655_CR81","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1186\/s13075-014-0486-0.PMID:25434931;PMCID:PMC4272554","volume":"16","author":"ML Stoll","year":"2014","unstructured":"Stoll ML, Kumar R, Morrow CD, Lefkowitz EJ, Cui X, Genin A, Cron RQ, Elson CO. Altered microbiota associated with abnormal humoral immune responses to commensal organisms in enthesitis-related arthritis. Arthritis Res Ther. 2014N 30;16(6):486. https:\/\/doi.org\/10.1186\/s13075-014-0486-0.PMID:25434931;PMCID:PMC4272554.","journal-title":"Arthritis Res Ther"},{"issue":"2022","key":"9655_CR82","doi-asserted-by":"publisher","first-page":"4646245","DOI":"10.1155\/2022\/4646245.PMID:36045662;PMCID:PMC9423962","volume":"22","author":"L Liu","year":"2022","unstructured":"Liu L, Chen Y, Wu Q, Shu A, Sun J. Sodium butyrate attenuated diabetes-induced intestinal inflammation by modulating gut microbiota. Evid Based Complement Alternat Med. 2022A;22(2022):4646245. https:\/\/doi.org\/10.1155\/2022\/4646245.PMID:36045662;PMCID:PMC9423962.","journal-title":"Evid Based Complement Alternat Med"},{"key":"9655_CR83","doi-asserted-by":"crossref","unstructured":"Umirah F, Neoh CF, Ramasamy K, Lim SM. Differential gut microbiota composition between type 2 diabetes mellitus patients and healthy controls: a systematic review. Diabetes Res Clin Pract. 2021M;173.","DOI":"10.1016\/j.diabres.2021.108689"},{"issue":"10","key":"9655_CR84","doi-asserted-by":"publisher","first-page":"250","DOI":"10.3390\/genes8100250.PMID:28973971;PMCID:PMC5664100","volume":"8","author":"SA Montandon","year":"2017","unstructured":"Montandon SA, Jornayvaz FR. Effects of antidiabetic drugs on gut microbiota composition. Genes (Basel). 2017S 30;8(10):250. https:\/\/doi.org\/10.3390\/genes8100250.PMID:28973971;PMCID:PMC5664100.","journal-title":"Genes (Basel)"},{"key":"9655_CR85","doi-asserted-by":"publisher","unstructured":"Hauner H. The mode of action of thiazolidinediones. Diabetes Metab Res Rev. 2002 Mar-Apr;18 Suppl 2:S10\u20135. https:\/\/doi.org\/10.1002\/dmrr.249.","DOI":"10.1002\/dmrr.249"},{"issue":"115 Suppl 8A","key":"9655_CR86","doi-asserted-by":"publisher","first-page":"42S","DOI":"10.1016\/j.amjmed.2003.09.005","volume":"8","author":"V Fonseca","year":"2003","unstructured":"Fonseca V. Effect of thiazolidinediones on body weight in patients with diabetes mellitus. Am J Med. 2003D;8(115 Suppl 8A):42S-48S. https:\/\/doi.org\/10.1016\/j.amjmed.2003.09.005.","journal-title":"Am J Med"},{"issue":"4","key":"9655_CR87","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0123703","volume":"10","author":"R Chen","year":"2015","unstructured":"Chen R, Yan J, Liu P, Wang Z. Effects of thiazolidinedione therapy on inflammatory markers of type 2 diabetes: a meta-analysis of randomized controlled trials. PLoS ONE. 2015A 21;10(4). https:\/\/doi.org\/10.1371\/journal.pone.0123703.","journal-title":"PLoS ONE"},{"key":"9655_CR88","doi-asserted-by":"publisher","unstructured":"Lima Ede A, Lima MM, Marques CD, Duarte AL, Pita Ida R, Pita MG. Peroxisome proliferator-activated receptor agonists (PPARs): a promising prospect in the treatment of psoriasis and psoriatic arthritis. An Bras Dermatol. 2013 Nov-Dec;88(6):1029\u201335. https:\/\/doi.org\/10.1590\/abd1806-4841.20132653.","DOI":"10.1590\/abd1806-4841.20132653"},{"issue":"2","key":"9655_CR89","doi-asserted-by":"publisher","first-page":"514","DOI":"10.3945\/ajcn.114.083246","volume":"100","author":"RE Steinert","year":"2014","unstructured":"Steinert RE, Schirra J, Meyer-Gerspach AC, Kienle P, Fischer H, Schulte F, Goeke B, Beglinger C. Effect of glucagon-like peptide-1 receptor antagonism on appetite and food intake in healthy men. Am J Clin Nutr. 2014A;100(2):514\u201323. https:\/\/doi.org\/10.3945\/ajcn.114.083246.","journal-title":"Am J Clin Nutr"},{"issue":"18","key":"9655_CR90","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpc.2024.100679","volume":"7","author":"FB Rivera","year":"2024","unstructured":"Rivera FB, Cruz LLA, Magalong JV, Ruyeras JMMJ, Aparece JP, Bantayan NRB, Lara-Breitinger K, Gulati M. Cardiovascular and renal outcomes of glucagon-like peptide 1 receptor agonists among patients with and without type 2 diabetes mellitus: A meta-analysis of randomized placebo-controlled trials. Am J Prev Cardiol. 2024M;7(18). https:\/\/doi.org\/10.1016\/j.ajpc.2024.100679.","journal-title":"Am J Prev Cardiol"},{"issue":"11","key":"9655_CR91","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.122.029282","volume":"12","author":"ED Michos","year":"2023","unstructured":"Michos ED, Lopez-Jimenez F, Gulati M. Role of glucagon-like peptide-1 receptor agonists in achieving weight loss and improving cardiovascular outcomes in people with overweight and obesity. J Am Heart Assoc. 2023J 6;12(11). https:\/\/doi.org\/10.1161\/JAHA.122.029282.","journal-title":"J Am Heart Assoc"},{"key":"9655_CR92","doi-asserted-by":"publisher","unstructured":"Papamargaritis D, Al-Najim W, Lim JZM, Crane J, Bodicoat DH, Barber S, Lean M, McGowan B, O'Shea D, Webb DR, Wilding JPH, le Roux CW, Davies MJ. Effectiveness of integrating a pragmatic pathway for prescribing Liraglutide 3.0 mg in weight management services (STRIVE study): a multicentre, open-label, parallel-group, randomized controlled trial. Lancet Reg Health Eur. 2024 Feb 9;39:100853. https:\/\/doi.org\/10.1016\/j.lanepe.2024.100853.","DOI":"10.1016\/j.lanepe.2024.100853"},{"key":"9655_CR93","doi-asserted-by":"publisher","unstructured":"Knop FK, Aroda VR, do Vale RD, Holst-Hansen T, Laursen PN, Rosenstock J, Rubino DM, Garvey WT; OASIS 1 Investigators. Oral SemaglutideSemaglutide 50 mg taken once per day in adults with overweight or obesity (OASIS 1): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet. 2023 Aug 26;402(10403):705\u2013719. https:\/\/doi.org\/10.1016\/S0140-6736(23)01185-6","DOI":"10.1016\/S0140-6736(23)01185-6"},{"key":"9655_CR94","doi-asserted-by":"publisher","unstructured":"Wilding JPH, Batterham RL, Calanna S, Davies M, Van Gaal LF, Lingvay I, McGowan BM, Rosenstock J, Tran MTD, Wadden TA, Wharton S, Yokote K, Zeuthen N, Kushner RF; STEP 1 Study Group. Once-weekly semaglutide in adults with overweight or obesity. N Engl J Med. 2021 Mar 18;384(11):989\u20131002. https:\/\/doi.org\/10.1056\/NEJMoa2032183.","DOI":"10.1056\/NEJMoa2032183"},{"issue":"13","key":"9655_CR95","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.920541","volume":"8","author":"G Lisco","year":"2022","unstructured":"Lisco G, De Tullio A, Disoteo O, De Geronimo V, Piazzolla G, De Pergola G, Giagulli VA, Jirillo E, Guastamacchia E, Sabb\u00e0 C, Triggiani V. Basal insulin intensification with GLP-1RA and dual GIP and GLP-1RA in patients with uncontrolled type 2 diabetes mellitus: a rapid review of randomized controlled trials and meta-analysis. Front Endocrinol (Lausanne). 2022S;8(13). https:\/\/doi.org\/10.3389\/fendo.2022.920541.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"2","key":"9655_CR96","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1016\/j.ando.2022.12.423","volume":"84","author":"AJ Scheen","year":"2023","unstructured":"Scheen AJ. Dual GIP\/GLP-1 receptor agonists: new advances for treating type-2 diabetes. Ann Endocrinol (Paris). 2023A;84(2):316\u201321. https:\/\/doi.org\/10.1016\/j.ando.2022.12.423.","journal-title":"Ann Endocrinol (Paris)"},{"issue":"8","key":"9655_CR97","doi-asserted-by":"publisher","first-page":"2290","DOI":"10.1111\/dom.15107","volume":"25","author":"M Asano","year":"2023","unstructured":"Asano M, Sekikawa A, Sugeno M, Matsuoka O, Robertson D, Hansen L. Safety\/tolerability, efficacy and pharmacokinetics of 600-\u03bcg cotadutide in Japanese type 2 diabetes patients with a body mass index of 25 kg\/m2 or higher: a phase I, randomized, double-blind, placebo-controlled study. Diabetes Obes Metab. 2023A;25(8):2290\u20139. https:\/\/doi.org\/10.1111\/dom.15107.","journal-title":"Diabetes Obes Metab"},{"issue":"6","key":"9655_CR98","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1038\/s42255-023-00812-z","volume":"5","author":"R Nogueiras","year":"2023","unstructured":"Nogueiras R, Nauck MA, Tsch\u00f6p MH. Gut hormone co-agonists for the treatment of obesity: from bench to bedside. Nat Metab. 2023J;5(6):933\u201344. https:\/\/doi.org\/10.1038\/s42255-023-00812-z.","journal-title":"Nat Metab"},{"issue":"21","key":"9655_CR99","doi-asserted-by":"publisher","first-page":"4673","DOI":"10.3390\/nu14214673","volume":"14","author":"S Volpe","year":"2022","unstructured":"Volpe S, Lisco G, Fanelli M, Racaniello D, Colaianni V, Triggiani D, Donghia R, Crudele L, Rinaldi R, Sabb\u00e0 C, Triggiani V, De Pergola G, Piazzolla G. Once-weekly subcutaneous semaglutide improves fatty liver disease in patients with type 2 diabetes: a 52-week prospective real-life study. Nutrients. 2022N 4;14(21):4673. https:\/\/doi.org\/10.3390\/nu14214673.","journal-title":"Nutrients"},{"issue":"14","key":"9655_CR100","doi-asserted-by":"publisher","first-page":"1240263","DOI":"10.3389\/fendo.2023.1240263","volume":"13","author":"S Volpe","year":"2023","unstructured":"Volpe S, Lisco G, Fanelli M, Racaniello D, Colaianni V, Lavarra V, Triggiani D, Crudele L, Triggiani V, Sabb\u00e0 C, De Pergola G, Piazzolla G. Oral semaglutide improves body composition and preserves lean mass in patients with type 2 diabetes: a 26-week prospective real-life study. Front Endocrinol (Lausanne). 2023S;13(14):1240263. https:\/\/doi.org\/10.3389\/fendo.2023.1240263.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"1","key":"9655_CR101","doi-asserted-by":"publisher","first-page":"63","DOI":"10.3390\/nu16010063","volume":"16","author":"G Lisco","year":"2023","unstructured":"Lisco G, Disoteo OE, De Tullio A, De Geronimo V, Giagulli VA, Monzani F, Jirillo E, Cozzi R, Guastamacchia E, De Pergola G, Triggiani V. Sarcopenia and diabetes: a detrimental liaison of advancing age. Nutrients. 2023D 25;16(1):63. https:\/\/doi.org\/10.3390\/nu16010063.","journal-title":"Nutrients"},{"issue":"3","key":"9655_CR102","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1530\/EDM-23-0017","volume":"2023","author":"AE Malavazos","year":"2023","unstructured":"Malavazos AE, Meregalli C, Sorrentino F, Vignati A, Dubini C, Scravaglieri V, Basilico S, Boniardi F, Spagnolo P, Malagoli P, Romanelli P, Secchi F, Iacobellis G. Semaglutide therapy decreases epicardial fat inflammation and improves psoriasis severity in patients affected by abdominal obesity and type-2 diabetes. Endocrinol Diabetes Metab Case Rep. 2023A 8;2023(3):23\u20130017. https:\/\/doi.org\/10.1530\/EDM-23-0017.","journal-title":"Endocrinol Diabetes Metab Case Rep"},{"key":"9655_CR103","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.diabres.2019.03.002","volume":"150","author":"X Xu","year":"2019","unstructured":"Xu X, Lin L, Chen P, Yu Y, Chen S, Chen X, Shao Z. Treatment with Liraglutide, a glucagon-like peptide-1 analogue, improves effectively the skin lesions of psoriasis patients with type 2 diabetes: a prospective cohort study. Diabetes Res Clin Pract. 2019A;150:167\u201373. https:\/\/doi.org\/10.1016\/j.diabres.2019.03.002.","journal-title":"Diabetes Res Clin Pract"},{"issue":"3","key":"9655_CR104","doi-asserted-by":"publisher","first-page":"1299","DOI":"10.1080\/09546634.2021.1882658","volume":"33","author":"G Chang","year":"2022","unstructured":"Chang G, Chen B, Zhang L. Efficacy of GLP-1rA, Liraglutide, in plaque psoriasis treatment with type 2 diabetes: a systematic review and meta-analysis of prospective cohort and before-after studies. J Dermatolog Treat. 2022M;33(3):1299\u2013305. https:\/\/doi.org\/10.1080\/09546634.2021.1882658.","journal-title":"J Dermatolog Treat"},{"issue":"3","key":"9655_CR105","doi-asserted-by":"publisher","first-page":"1428","DOI":"10.1080\/09546634.2020.1826392","volume":"33","author":"L Lin","year":"2022","unstructured":"Lin L, Xu X, Yu Y, Ye H, He X, Chen S, Chen X, Shao Z, Chen P. Glucagon-like peptide-1 receptor agonist liraglutide therapy for psoriasis patients with type 2 diabetes: a randomized-controlled trial. J Dermatolog Treat. 2022M;33(3):1428\u201334. https:\/\/doi.org\/10.1080\/09546634.2020.1826392.","journal-title":"J Dermatolog Treat"},{"issue":"2","key":"9655_CR106","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.1007\/s11010-024-05066-1","volume":"480","author":"Y Yang","year":"2025","unstructured":"Yang Y, Wang Y, Zhou Y, Deng J, Wu L. Tirzepatide alleviates oxidative stress and inflammation in diabetic nephropathy via IL-17 signaling pathway. Mol Cell Biochem. 2025F;480(2):1241\u201354. https:\/\/doi.org\/10.1007\/s11010-024-05066-1.","journal-title":"Mol Cell Biochem"},{"issue":"8","key":"9655_CR107","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.777861","volume":"20","author":"JI Fonseca-Correa","year":"2021","unstructured":"Fonseca-Correa JI, Correa-Rotter R. Sodium-glucose co-transporter 2 inhibitors mechanisms of action: a review. Front Med (Lausanne). 2021D;20(8). https:\/\/doi.org\/10.3389\/fmed.2021.777861.","journal-title":"Front Med (Lausanne)"},{"issue":"14","key":"9655_CR108","doi-asserted-by":"publisher","first-page":"1216160","DOI":"10.3389\/fendo.2023.1216160","volume":"20","author":"T Kongmalai","year":"2023","unstructured":"Kongmalai T, Hadnorntun P, Leelahavarong P, Kongmalai P, Srinonprasert V, Chirakarnjanakorn S, Chaikledkaew U, McKay G, Attia J, Thakkinstian A. Comparative cardiovascular benefits of individual SGLT2 inhibitors in type 2 diabetes and heart failure: a systematic review and network meta-analysis of randomized controlled trials. Front Endocrinol (Lausanne). 2023D;20(14):1216160. https:\/\/doi.org\/10.3389\/fendo.2023.1216160.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"25","key":"9655_CR109","doi-asserted-by":"publisher","first-page":"2377","DOI":"10.1016\/j.jacc.2023.04.034","volume":"81","author":"MS Usman","year":"2023","unstructured":"Usman MS, Siddiqi TJ, Anker SD, Bakris GL, Bhatt DL, Filippatos G, Fonarow GC, Greene SJ, Januzzi JL Jr, Khan MS, Kosiborod MN, McGuire DK, Pi\u00f1a IL, Rosenstock J, Vaduganathan M, Verma S, Zieroth S, Butler J. Effect of SGLT2 inhibitors on cardiovascular outcomes across various patient populations. J Am Coll Cardiol. 2023J 27;81(25):2377\u201387. https:\/\/doi.org\/10.1016\/j.jacc.2023.04.034.","journal-title":"J Am Coll Cardiol"},{"issue":"3","key":"9655_CR110","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1007\/s00535-017-1415-1","volume":"53","author":"Y Sumida","year":"2018","unstructured":"Sumida Y, Yoneda M. Current and future pharmacological therapies for NAFLD\/NASH. J Gastroenterol. 2018M;53(3):362\u201376. https:\/\/doi.org\/10.1007\/s00535-017-1415-1.","journal-title":"J Gastroenterol"},{"issue":"10","key":"9655_CR111","doi-asserted-by":"publisher","first-page":"1328","DOI":"10.1136\/ard-2023-224242","volume":"82","author":"XY Zhao","year":"2023","unstructured":"Zhao XY, Li SS, He YX, Yan LJ, Lv F, Liang QM, Gan YH, Han LP, Xu HD, Li YC, Qi YY. SGLT2 inhibitors alleviated podocyte damage in lupus nephritis by decreasing inflammation and enhancing autophagy. Ann Rheum Dis. 2023O;82(10):1328\u201340. https:\/\/doi.org\/10.1136\/ard-2023-224242.","journal-title":"Ann Rheum Dis"},{"issue":"19","key":"9655_CR112","doi-asserted-by":"publisher","first-page":"10822","DOI":"10.3390\/ijms221910822","volume":"22","author":"A Winiarska","year":"2021","unstructured":"Winiarska A, Knysak M, Nabrdalik K, Gumprecht J, Stomp\u00f3r T. Inflammation and oxidative stress in diabetic kidney disease: the targets for SGLT2 inhibitors and GLP-1 receptor agonists. Int J Mol Sci. 2021O 6;22(19):10822. https:\/\/doi.org\/10.3390\/ijms221910822.","journal-title":"Int J Mol Sci"},{"issue":"9","key":"9655_CR113","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1038\/nri3707","volume":"14","author":"SL Gaffen","year":"2014","unstructured":"Gaffen SL, Jain R, Garg AV, Cua DJ. The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing. Nat Rev Immunol. 2014S;14(9):585\u2013600. https:\/\/doi.org\/10.1038\/nri3707.","journal-title":"Nat Rev Immunol"},{"issue":"2","key":"9655_CR114","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1038\/ncb2152","volume":"13","author":"J Kim","year":"2011","unstructured":"Kim J, Kundu M, Viollet B, Guan KL. AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat Cell Biol. 2011F;13(2):132\u201341. https:\/\/doi.org\/10.1038\/ncb2152.","journal-title":"Nat Cell Biol"},{"key":"9655_CR115","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2021.107492","volume":"94","author":"Z Meng","year":"2021","unstructured":"Meng Z, Liu X, Li T, Fang T, Cheng Y, Han L, Sun B, Chen L. The SGLT2 inhibitor empagliflozin negatively regulates IL-17\/IL-23 axis-mediated inflammatory responses in T2DM with NAFLD via the AMPK\/mTOR\/autophagy pathway. Int Immunopharmacol. 2021M;94. https:\/\/doi.org\/10.1016\/j.intimp.2021.107492.","journal-title":"Int Immunopharmacol"},{"key":"9655_CR116","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2020.109825","volume":"77","author":"S Sukhanov","year":"2021","unstructured":"Sukhanov S, Higashi Y, Yoshida T, Mummidi S, Aroor AR, Jeffrey Russell J, Bender SB, DeMarco VG, Chandrasekar B. The SGLT2 inhibitor empagliflozin attenuates interleukin-17A-induced human aortic smooth muscle cell proliferation and migration by targeting TRAF3IP2\/ROS\/NLRP3\/Caspase-1-dependent IL-1\u03b2 and IL-18 secretion. Cell Signal. 2021J;77. https:\/\/doi.org\/10.1016\/j.cellsig.2020.109825.","journal-title":"Cell Signal"},{"issue":"3","key":"9655_CR117","doi-asserted-by":"publisher","DOI":"10.1002\/jbt.70204","volume":"39","author":"RA Elrashidy","year":"2025","unstructured":"Elrashidy RA, Mohamad HE, Aal SMA, Mohamed SR, Tolba SM, Mahmoud YK. Repurposing secukinumab and dapagliflozin as candidate therapies to mitigate the renal toxicity of sunitinib in rats through suppressing IL-17-mediated pyroptosis and promoting autophagy. J Biochem Mol Toxicol. 2025M;39(3). https:\/\/doi.org\/10.1002\/jbt.70204.","journal-title":"J Biochem Mol Toxicol"},{"key":"9655_CR118","doi-asserted-by":"publisher","unstructured":"Bliddal H, Bays H, Czernichow S, Udd\u00e9n Hemmingsson J, Hjelmes\u00e6th J, Hoffmann Morville T, Koroleva A, Skov Neergaard J, V\u00e9lez S\u00e1nchez P, Wharton S, Wizert A, Kristensen LE; STEP 9 Study Group. Once-weekly semaglutide in persons with obesity and knee osteoarthritis. N Engl J Med. 2024 Oct 31;391(17):1573\u20131583. https:\/\/doi.org\/10.1056\/NEJMoa2403664.","DOI":"10.1056\/NEJMoa2403664"},{"issue":"10297","key":"9655_CR119","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/S0140-6736(21)01242-3","volume":"398","author":"TH Jafar","year":"2021","unstructured":"Jafar TH. FDA approval of dapagliflozin for chronic kidney disease: a remarkable achievement? Lancet. 2021J 24;398(10297):283\u20134. https:\/\/doi.org\/10.1016\/S0140-6736(21)01242-3. Epub 2021 Jun 4 PMID: 34097853.","journal-title":"Lancet"},{"issue":"7","key":"9655_CR120","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1586\/14779072.2015.1054810","volume":"13","author":"EW Iepsen","year":"2015","unstructured":"Iepsen EW, Torekov SS, Holst JJ. Liraglutide for type 2 diabetes and obesity: a 2015 update. Expert Rev Cardiovasc Ther. 2015;13(7):753\u201367. https:\/\/doi.org\/10.1586\/14779072.2015.1054810. PMID: 26106933.","journal-title":"Expert Rev Cardiovasc Ther"}],"container-title":["Immunologic Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12026-025-09655-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12026-025-09655-0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12026-025-09655-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T07:30:10Z","timestamp":1770190210000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12026-025-09655-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,11]]},"references-count":120,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["9655"],"URL":"https:\/\/doi.org\/10.1007\/s12026-025-09655-0","relation":{},"ISSN":["0257-277X","1559-0755"],"issn-type":[{"value":"0257-277X","type":"print"},{"value":"1559-0755","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,11]]},"assertion":[{"value":"23 October 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"106"}}