{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T11:17:27Z","timestamp":1775042247656,"version":"3.50.1"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2013,9,20]],"date-time":"2013-09-20T00:00:00Z","timestamp":1379635200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurocrit Care"],"published-print":{"date-parts":[[2014,8]]},"DOI":"10.1007\/s12028-013-9914-2","type":"journal-article","created":{"date-parts":[[2013,9,19]],"date-time":"2013-09-19T16:48:24Z","timestamp":1379609304000},"page":"108-113","source":"Crossref","is-referenced-by-count":59,"title":["Serotonin Syndrome in the Intensive Care Unit: Clinical Presentations and Precipitating Medications"],"prefix":"10.1007","volume":"21","author":[{"given":"Swetha","family":"Pedavally","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer E.","family":"Fugate","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro A.","family":"Rabinstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,9,20]]},"reference":[{"key":"9914_CR1","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1176\/ajp.148.6.705","volume":"148","author":"H Sternbach","year":"1991","unstructured":"Sternbach H. The serotonin syndrome. Am J Psychiatry. 1991;148:705\u201313.","journal-title":"Am J Psychiatry"},{"key":"9914_CR2","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1056\/NEJMra041867","volume":"352","author":"EW Boyer","year":"2005","unstructured":"Boyer EW, Shannon M. The serotonin syndrome. N Engl J Med. 2005;352:112\u20131112.","journal-title":"N Engl J Med"},{"key":"9914_CR3","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1097\/01.wnf.0000177642.89888.85","volume":"28","author":"GK Isbister","year":"2005","unstructured":"Isbister GK, Buckley NA. The pathophysiology of serotonin toxicity in animals and humans: implications for diagnosis and treatment. Clin Neuropharmacol. 2005;28:205\u201314.","journal-title":"Clin Neuropharmacol"},{"key":"9914_CR4","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1093\/qjmed\/hcg109","volume":"96","author":"EJ Dunkley","year":"2003","unstructured":"Dunkley EJ, Isbister GK, Sibbritt D, et al. The Hunter Serotonin Toxicity Criteria: simple and accurate diagnostic decision rules for serotonin toxicity. QJM. 2003;96:635\u201342.","journal-title":"QJM"},{"key":"9914_CR5","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/S0749-0704(05)70368-7","volume":"13","author":"KC Mills","year":"1997","unstructured":"Mills KC. Serotonin syndrome: a clinical update. Crit Care Clin. 1997;13:763\u201383.","journal-title":"Crit Care Clin"},{"key":"9914_CR6","doi-asserted-by":"crossref","first-page":"390","DOI":"10.2165\/00002018-199717060-00005","volume":"17","author":"PB Mitchell","year":"1997","unstructured":"Mitchell PB. Drug interactions of clinical significance with selective serotonin reuptake inhibitors. Drug Saf. 1997;17:390\u2013406.","journal-title":"Drug Saf"},{"key":"9914_CR7","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1213\/01.ane.0000247699.81580.eb","volume":"103","author":"MT Keegan","year":"2006","unstructured":"Keegan MT, Brown DR, Rabinstein AA. Serotonin syndrome from the interaction of cyclobenzaprine with other serotonergic drugs. Anesth Analg. 2006;103:1466\u20138.","journal-title":"Anesth Analg"},{"key":"9914_CR8","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/0140-6736(93)92774-N","volume":"342","author":"PJ Neuvonen","year":"1993","unstructured":"Neuvonen PJ, Pohjola-Sintonen S, Tacke U, Vuori E. Five fatal cases of serotonin syndrome after moclobemide\u2013citalopram or moclobemide\u2013clomipramine overdoses. Lancet. 1993;342:1419.","journal-title":"Lancet"},{"key":"9914_CR9","doi-asserted-by":"crossref","first-page":"911","DOI":"10.3109\/15563650.2012.746424","volume":"50","author":"AC Bronstein","year":"2012","unstructured":"Bronstein AC, Spyker DA, Cantilena LR Jr, et al. 2011 Annual report of the American Association of Poison Control Centers\u2019 National Poison Data System (NPDS): 29th Annual Report. Clin Toxicol (Phila). 2012;50:911\u20131164.","journal-title":"Clin Toxicol (Phila)"},{"key":"9914_CR10","doi-asserted-by":"crossref","first-page":"2662","DOI":"10.1097\/CCM.0b013e31825ae0f8","volume":"40","author":"JO Bienvenu","year":"2012","unstructured":"Bienvenu JO, Neufeld KJ, Needham DM. Treatment of four psychiatric emergencies in the intensive care unit. Crit Care Med. 2012;40:2662\u201370.","journal-title":"Crit Care Med"},{"key":"9914_CR11","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1097\/00003246-199606000-00034","volume":"24","author":"PK Nijhawan","year":"1996","unstructured":"Nijhawan PK, Katz G, Winter S. Psychiatric illness and the serotonin syndrome: an emerging adverse drug effect leading to intensive care unit admission. Crit Care Med. 1996;24:1086\u20139.","journal-title":"Crit Care Med"},{"key":"9914_CR12","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1097\/00003246-200202000-00033","volume":"30","author":"V Chechani","year":"2002","unstructured":"Chechani V. Serotonin syndrome presenting as hypotonic coma and apnea: potentially fatal complications of selective serotonin receptor inhibitor therapy. Crit Care Med. 2002;30:473\u20136.","journal-title":"Crit Care Med"},{"key":"9914_CR13","first-page":"272","volume":"11","author":"LE Torre","year":"2009","unstructured":"Torre LE, Menon R, Power BM. Prolonged serotonin toxicity with proserotonergic drugs in the intensive care unit. Crit Care Resusc. 2009;11:272\u20135.","journal-title":"Crit Care Resusc"},{"key":"9914_CR14","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.jclinane.2011.04.017","volume":"24","author":"S Gollapudy","year":"2012","unstructured":"Gollapudy S, Kumar V, Dhamee MS. A case of serotonin syndrome precipitated by fentanyl and ondansetron in a patient receiving paroxetine, duloxetine, and bupropion. J Clin Anesth. 2012;24:251\u20132.","journal-title":"J Clin Anesth"},{"key":"9914_CR15","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1093\/bja\/aei210","volume":"95","author":"PK Gillman","year":"2005","unstructured":"Gillman PK. Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity. Br J Anaesth. 2005;95:434\u201341.","journal-title":"Br J Anaesth"},{"key":"9914_CR16","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1097\/ALN.0b013e31823940c0","volume":"115","author":"R Rastogi","year":"2011","unstructured":"Rastogi R, Swarm RA, Patel TA. Case scenario: opioid association with serotonin syndrome: implications to the practitioners. Anesthesiology. 2011;115:1291\u20138.","journal-title":"Anesthesiology"},{"key":"9914_CR17","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1136\/bmj.2.5321.1752-a","volume":"2","author":"PH Denton","year":"1962","unstructured":"Denton PH, Borrelli VM, Edwards NV. Dangers of monoamine oxidase inhibitors. BMJ. 1962;2:1752\u20133.","journal-title":"BMJ"},{"key":"9914_CR18","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1086\/503839","volume":"42","author":"KR Lawrence","year":"2006","unstructured":"Lawrence KR, Adra M, Gillman PK. Serotonin toxicity associated with the use of linezolid: a review of postmarketing data. Clin Infect Dis. 2006;42:1578\u201383.","journal-title":"Clin Infect Dis"},{"key":"9914_CR19","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1038\/sj.bjp.0707430","volume":"152","author":"RR Ramsay","year":"2007","unstructured":"Ramsay RR, Dunford C, Gillman PK. Methylene blue and serotonin toxicity: inhibition of monoamine oxidase A (MAO A) confirms a theoretical prediction. Br J Pharmacol. 2007;152:946\u201351.","journal-title":"Br J Pharmacol"},{"key":"9914_CR20","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/S0736-4679(98)00057-2","volume":"16","author":"A Graudins","year":"1998","unstructured":"Graudins A, Stearman A, Chan B. Treatment of the serotonin syndrome with cyproheptadine. J Emerg Med. 1998;16:615\u20139.","journal-title":"J Emerg Med"},{"key":"9914_CR21","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1345\/aph.10203","volume":"35","author":"WW McDaniel","year":"2001","unstructured":"McDaniel WW. Serotonin syndrome: early management with cyproheptadine. Ann Pharmacother. 2001;35:870\u20133.","journal-title":"Ann Pharmacother"},{"key":"9914_CR22","first-page":"871","volume":"49","author":"FJ Mackay","year":"1999","unstructured":"Mackay FJ, Dunn NR, Mann RD. Antidepressants and the serotonin syndrome in general practice. Br J Gen Pract. 1999;49:871\u20134.","journal-title":"Br J Gen Pract"},{"key":"9914_CR23","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1212\/WNL.45.2.219","volume":"45","author":"RA Bodner","year":"1995","unstructured":"Bodner RA, Lynch T, Lewis L, et al. Serotonin syndrome. Neurology. 1995;45:219\u201323.","journal-title":"Neurology"}],"container-title":["Neurocritical Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12028-013-9914-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12028-013-9914-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12028-013-9914-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,6]],"date-time":"2022-03-06T13:23:21Z","timestamp":1646573001000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12028-013-9914-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,20]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["9914"],"URL":"https:\/\/doi.org\/10.1007\/s12028-013-9914-2","relation":{},"ISSN":["1541-6933","1556-0961"],"issn-type":[{"value":"1541-6933","type":"print"},{"value":"1556-0961","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9,20]]}}}