{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T03:06:18Z","timestamp":1792638378800,"version":"4.5.0"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2018,6,11]],"date-time":"2018-06-11T00:00:00Z","timestamp":1528675200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurocrit Care"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1007\/s12028-018-0560-6","type":"journal-article","created":{"date-parts":[[2018,6,11]],"date-time":"2018-06-11T14:11:23Z","timestamp":1528726283000},"page":"491-495","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Safety and Efficiency of Intravenous Push Lacosamide Administration"],"prefix":"10.1007","volume":"29","author":[{"given":"K. Erin","family":"Davidson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Newell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalid","family":"Alsherbini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Krushinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. Morgan","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,6,11]]},"reference":[{"key":"560_CR1","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1111\/j.1600-0404.2010.01423.x","volume":"123","author":"C Kellinghaus","year":"2011","unstructured":"Kellinghaus C, Berning S, Immisch I, et al. Intravenous lacosamide for treatment of status epilepticus. Acta Neurol Scand. 2011;123:137\u201341.","journal-title":"Acta Neurol Scand"},{"key":"560_CR2","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s12028-012-9695-z","volume":"17","author":"GM Brophy","year":"2012","unstructured":"Brophy GM, Bell R, Claassen J, et al. Guidelines for the evaluation and management of status epilepticus. Neurocrit Care. 2012;17:3\u201323.","journal-title":"Neurocrit Care"},{"key":"560_CR3","unstructured":"Vimpat (lacosamide) [prescribing information]. Smyrna, GA: ICB Inc; 2017."},{"key":"560_CR4","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.yebeh.2017.07.005","volume":"76","author":"UK Misra","year":"2017","unstructured":"Misra UK, Dubey D, Kalita J. Comparison of lacosamide versus sodium valproate in status epilepticus: a pilot study. Epilepsy Behav. 2017;76:110\u20133.","journal-title":"Epilepsy Behav"},{"key":"560_CR5","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1007\/s12028-016-0322-2","volume":"26","author":"CR Newey","year":"2017","unstructured":"Newey CR, Le NM, Ahrens C, Sahota P, Hantus S. The Safety and effectiveness of intravenous lacosamide for refractory status epilepticus in the critically ill. Neurocrit Care. 2017;26:273\u20139.","journal-title":"Neurocrit Care"},{"key":"560_CR6","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1007\/s12028-010-9501-8","volume":"14","author":"H Goodwin","year":"2011","unstructured":"Goodwin H, Hinson HE, Shermock KM, Karanjia N, Lewin JJ 3rd. The use of lacosamide in refractory status epilepticus. Neurocrit Care. 2011;14:348\u201353.","journal-title":"Neurocrit Care"},{"key":"560_CR7","doi-asserted-by":"publisher","first-page":"e148","DOI":"10.1111\/j.1528-1167.2011.03204.x","volume":"52","author":"J Hofler","year":"2011","unstructured":"Hofler J, Unterberger I, Dobesberger J, Kuchukhidze G, Walser G, Trinka E. Intravenous lacosamide in status epilepticus and seizure clusters. Epilepsia. 2011;52:e148\u201352.","journal-title":"Epilepsia"},{"key":"560_CR8","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1016\/j.yebeh.2011.02.006","volume":"20","author":"LU Krause","year":"2011","unstructured":"Krause LU, Brodowski KO, Kellinghaus C. Atrioventricular block following lacosamide intoxication. Epilepsy Behav. 2011;20:725\u20137.","journal-title":"Epilepsy Behav"},{"key":"560_CR9","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.yebeh.2008.12.009","volume":"14","author":"C Kellinghaus","year":"2009","unstructured":"Kellinghaus C, Berning S, Besselmann M. Intravenous lacosamide as successful treatment for nonconvulsive status epilepticus after failure of first-line therapy. Epilepsy Behav. 2009;14:429\u201331.","journal-title":"Epilepsy Behav"},{"key":"560_CR10","unstructured":"Small-volume parenteral solutions shortages. American Society of Health System Pharmacists. 2017. \n                    http:\/\/www.ashp.org\/Drug-Shortages\/Shortage-Resources\/Publications\/Small-Volume-Parenteral-Solutions-Shortages\n                    \n                  . Accessed 16 Jan 2018."},{"key":"560_CR11","unstructured":"Safe practice guidelines for adult IV push medications. ISMP. 2015. \n                    http:\/\/www.ismp.org\/Tools\/guidelines\/IVSummitPush\/IVPushMedGuidelines.pdf\n                    \n                  . Accessed 16 Jan 2018."}],"container-title":["Neurocritical Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12028-018-0560-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12028-018-0560-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12028-018-0560-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,10]],"date-time":"2019-06-10T19:07:51Z","timestamp":1560193671000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12028-018-0560-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,11]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["560"],"URL":"https:\/\/doi.org\/10.1007\/s12028-018-0560-6","relation":{},"ISSN":["1541-6933","1556-0961"],"issn-type":[{"value":"1541-6933","type":"print"},{"value":"1556-0961","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6,11]]},"assertion":[{"value":"11 June 2018","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"All authors declare that they have no conflict of interest to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All data were extracted from the electronic medical record, and the study was approved by the University of Tennessee Institutional Review Board.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}