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Dr Mayer reports having received personal consulting fees from Edge Therapeutics and Idorsia Pharmaceuticals outside of the submitted work. Dr Amin-Hanjani, has nothing to disclose. Dr Vergouwen has nothing to disclose. Dr de Oliveira Manoel has nothing to disclose. Dr van der Jagt has nothing to disclose. Dr Bambakidis has nothing to disclose. Dr Brophy has nothing to disclose. Dr Bulsara has nothing to disclose. Dr Claassesn reports grants from Charles A Dana Foundation, grants from James S McDonnell Foundation, from NIH: The Stroke Hyperglycemia Insutlin Network Effort (SHINE) Trial, grants from NIH: I-SPOT, grants from NIH: Established Status Epilepticus Treatment Trial (ESETT), grants from BARD: Intrepid, grants from NIH: Futility Study of Deferoxamine Mesylate in Intracerebral Hemorrhage (I-DEF), grants from NIH\/NLM: BIGDATA: Causal Inference in Large-Scale Time Series with Rare and Latent Events, grants from NIH: Rhapsody (ZZ-3K3A-201), other from iCE Neurosystems, outside the submitted work. Dr Connolly has nothing to disclose. Dr Hoffer has nothing to disclose. Dr Hoh has nothing to disclose. Dr Holloway has nothing to disclose. Dr Kelly has nothing to disclose. Dr Nakaji has nothing to disclose. Dr Rabinstein has nothing to disclose. Dr Vajkoczy has nothing to disclose. Dr Woo has nothing to disclose. Dr Zipfel has nothing to disclose.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval\/informed consent"}}]}}