{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T07:25:55Z","timestamp":1791876355601,"version":"4.3.4"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2020,1,2]],"date-time":"2020-01-02T00:00:00Z","timestamp":1577923200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,1,2]],"date-time":"2020-01-02T00:00:00Z","timestamp":1577923200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurocrit Care"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1007\/s12028-019-00899-x","type":"journal-article","created":{"date-parts":[[2020,2,3]],"date-time":"2020-02-03T14:59:29Z","timestamp":1580741969000},"page":"405-413","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["The Role of Desmopressin on Hematoma Expansion in Patients with Mild Traumatic Brain Injury Prescribed Pre-injury Antiplatelet Medications"],"prefix":"10.1007","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9054-8218","authenticated-orcid":false,"given":"Jeffrey F.","family":"Barletta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Abdul-Rahman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott T.","family":"Hall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia J.","family":"Mangram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James K.","family":"Dzandu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer A.","family":"Frontera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Zach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,1,2]]},"reference":[{"key":"899_CR1","doi-asserted-by":"publisher","first-page":"2160","DOI":"10.1161\/STR.0000000000000024","volume":"45","author":"WN Kernan","year":"2014","unstructured":"Kernan WN, Ovbiagele B, Black HR, et al. Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association\/American Stroke Association. Stroke. 2014;45:2160\u2013236.","journal-title":"Stroke"},{"key":"899_CR2","doi-asserted-by":"publisher","first-page":"2458","DOI":"10.1161\/CIR.0b013e318235eb4d","volume":"124","author":"SC Smith Jr","year":"2011","unstructured":"Smith SC Jr, Benjamin EJ, Bonow RO, et al. AHA\/ACCF secondary prevention and risk reduction therapy for patients with coronary and other atherosclerotic vascular disease: 2011 update: a guideline from the American Heart Association and American College of Cardiology Foundation. Circulation. 2011;124:2458\u201373.","journal-title":"Circulation"},{"key":"899_CR3","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1097\/TA.0b013e31825b85f1","volume":"73","author":"VA Ferraris","year":"2012","unstructured":"Ferraris VA, Bernard AC, Hyde B. The impact of antiplatelet drugs on trauma outcomes. J Trauma Acute Care Surg. 2012;73:492\u20137.","journal-title":"J Trauma Acute Care Surg"},{"key":"899_CR4","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1097\/TA.0b013e3182aafcf0","volume":"76","author":"B Joseph","year":"2014","unstructured":"Joseph B, Pandit V, Aziz H, et al. Clinical outcomes in traumatic brain injury patients on preinjury clopidogrel: a prospective analysis. J Trauma Acute Care Surg. 2014;76:817\u201320.","journal-title":"J Trauma Acute Care Surg"},{"key":"899_CR5","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1097\/TA.0000000000000107","volume":"76","author":"KA Peck","year":"2014","unstructured":"Peck KA, Calvo RY, Schechter MS, et al. The impact of preinjury anticoagulants and prescription antiplatelet agents on outcomes in older patients with traumatic brain injury. J Trauma Acute Care Surg. 2014;76:431\u20136.","journal-title":"J Trauma Acute Care Surg"},{"key":"899_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1089\/neu.2015.4393","volume":"34","author":"CL van den Brand","year":"2017","unstructured":"van den Brand CL, Tolido T, Rambach AH, Hunink MG, Patka P, Jellema K. Systematic review and meta-analysis: is pre-injury antiplatelet therapy associated with traumatic intracranial hemorrhage? J Neurotrauma. 2017;34:1\u20137.","journal-title":"J Neurotrauma"},{"key":"899_CR7","doi-asserted-by":"publisher","first-page":"1000","DOI":"10.1212\/01.wnl.0000179178.37713.69","volume":"65","author":"K Toyoda","year":"2005","unstructured":"Toyoda K, Okada Y, Minematsu K, et al. Antiplatelet therapy contributes to acute deterioration of intracerebral hemorrhage. Neurology. 2005;65:1000\u20134.","journal-title":"Neurology"},{"key":"899_CR8","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1159\/000177924","volume":"27","author":"K Toyoda","year":"2009","unstructured":"Toyoda K, Yasaka M, Nagata K, et al. Antithrombotic therapy influences location, enlargement, and mortality from intracerebral hemorrhage. The Bleeding with Antithrombotic Therapy (BAT) Retrospective Study. Cerebrovasc Dis (Basel, Switzerland). 2009;27:151\u20139.","journal-title":"Cerebrovasc Dis (Basel, Switzerland)"},{"key":"899_CR9","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1227\/01.NEU.0000351769.39990.16","volume":"65","author":"AM Naidech","year":"2009","unstructured":"Naidech AM, Bendok BR, Garg RK, et al. Reduced platelet activity is associated with more intraventricular hemorrhage. Neurosurgery. 2009;65:684\u20138 (discussion 8).","journal-title":"Neurosurgery"},{"key":"899_CR10","doi-asserted-by":"publisher","first-page":"2398","DOI":"10.1161\/STROKEAHA.109.550939","volume":"40","author":"AM Naidech","year":"2009","unstructured":"Naidech AM, Jovanovic B, Liebling S, et al. Reduced platelet activity is associated with early clot growth and worse 3-month outcome after intracerebral hemorrhage. Stroke. 2009;40:2398\u2013401.","journal-title":"Stroke"},{"key":"899_CR11","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1007\/s12028-015-0222-x","volume":"24","author":"JA Frontera","year":"2016","unstructured":"Frontera JA, Lewin JJ 3rd, Rabinstein AA, et al. Guideline for reversal of antithrombotics in intracranial hemorrhage: a statement for healthcare professionals from the Neurocritical Care Society and Society of Critical Care Medicine. Neurocrit Care. 2016;24:6\u201346.","journal-title":"Neurocrit Care"},{"key":"899_CR12","doi-asserted-by":"publisher","first-page":"298767","DOI":"10.1155\/2014\/298767","volume":"2014","author":"T Kapapa","year":"2014","unstructured":"Kapapa T, Rohrer S, Struve S, et al. Desmopressin acetate in intracranial haemorrhage. Neurol Res Int. 2014;2014:298767.","journal-title":"Neurol Res Int"},{"key":"899_CR13","doi-asserted-by":"publisher","first-page":"1815","DOI":"10.1089\/neu.2014.3728","volume":"32","author":"DY Kim","year":"2015","unstructured":"Kim DY, O\u2019Leary M, Nguyen A, et al. The effect of platelet and desmopressin administration on early radiographic progression of traumatic intracranial hemorrhage. J Neurotrauma. 2015;32:1815\u201321.","journal-title":"J Neurotrauma"},{"key":"899_CR14","doi-asserted-by":"publisher","first-page":"2451","DOI":"10.1161\/STROKEAHA.114.006061","volume":"45","author":"AM Naidech","year":"2014","unstructured":"Naidech AM, Maas MB, Levasseur-Franklin KE, et al. Desmopressin improves platelet activity in acute intracerebral hemorrhage. Stroke. 2014;45:2451\u20133.","journal-title":"Stroke"},{"key":"899_CR15","doi-asserted-by":"publisher","first-page":"1304","DOI":"10.1161\/01.STR.27.8.1304","volume":"27","author":"RU Kothari","year":"1996","unstructured":"Kothari RU, Brott T, Broderick JP, et al. The ABCs of measuring intracerebral hemorrhage volumes. Stroke. 1996;27:1304\u20135.","journal-title":"Stroke"},{"key":"899_CR16","doi-asserted-by":"publisher","first-page":"1799","DOI":"10.1161\/01.STR.29.9.1799","volume":"29","author":"JM Gebel","year":"1998","unstructured":"Gebel JM, Sila CA, Sloan MA, et al. Comparison of the ABC\/2 estimation technique to computer-assisted volumetric analysis of intraparenchymal and subdural hematomas complicating the GUSTO-1 trial. Stroke. 1998;29:1799\u2013801.","journal-title":"Stroke"},{"key":"899_CR17","doi-asserted-by":"publisher","first-page":"e0199809","DOI":"10.1371\/journal.pone.0199809","volume":"13","author":"SY Won","year":"2018","unstructured":"Won SY, Zagorcic A, Dubinski D, et al. Excellent accuracy of ABC\/2 volume formula compared to computer-assisted volumetric analysis of subdural hematomas. PLoS ONE. 2018;13:e0199809.","journal-title":"PLoS ONE"},{"key":"899_CR18","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1016\/j.amepre.2014.11.005","volume":"48","author":"CD Williams","year":"2015","unstructured":"Williams CD, Chan AT, Elman MR, et al. Aspirin use among adults in the U.S.: results of a national survey. Am J Prev Med. 2015;48:501\u20138.","journal-title":"Am J Prev Med"},{"key":"899_CR19","doi-asserted-by":"publisher","first-page":"993","DOI":"10.15585\/mmwr.mm6537a2","volume":"65","author":"G Bergen","year":"2016","unstructured":"Bergen G, Stevens MR, Burns ER. Falls and fall injuries among adults aged\u2009\u2265 65 years\u2014United States, 2014. MMWR Morb Mortal Wkly Rep. 2016;65:993\u20138.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"899_CR20","first-page":"1","volume":"66","author":"CA Taylor","year":"2017","unstructured":"Taylor CA, Bell JM, Breiding MJ, Xu L. Traumatic brain injury-related emergency department visits, hospitalizations, and deaths-United States, 2007 and 2013. Morb Mort Wk Rep Surveill Summ (Washington, DC: 2002). 2017;66:1\u201316.","journal-title":"Morb Mort Wk Rep Surveill Summ (Washington, DC: 2002)"},{"key":"899_CR21","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1016\/S0140-6736(17)30770-5","volume":"390","author":"L Li","year":"2017","unstructured":"Li L, Geraghty OC, Mehta Z, Rothwell PM. Age-specific risks, severity, time course, and outcome of bleeding on long-term antiplatelet treatment after vascular events: a population-based cohort study. Lancet (London, England). 2017;390:490\u20139.","journal-title":"Lancet (London, England)"},{"key":"899_CR22","first-page":"98","volume-title":"The European guideline on management of major bleeding and coagulopathy following traumam","author":"DR Spahn","year":"2019","unstructured":"Spahn DR, Bouillon B, Cerny V, et al. The European guideline on management of major bleeding and coagulopathy following traumam, vol. 23. 5th ed. London: Critical Care; 2019. p. 98.","edition":"5"},{"key":"899_CR23","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1186\/s13054-019-2352-6","volume":"23","author":"M Wiegele","year":"2019","unstructured":"Wiegele M, Schochl H, Haushofer A, et al. Diagnostic and therapeutic approach in adult patients with traumatic brain injury receiving oral anticoagulant therapy: an Austrian interdisciplinary consensus statement. Crit Care (London, England). 2019;23:62.","journal-title":"Crit Care (London, England)"},{"key":"899_CR24","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1016\/S0140-6736(77)91197-7","volume":"1","author":"PM Mannucci","year":"1977","unstructured":"Mannucci PM, Ruggeri ZM, Pareti FI, Capitanio A. 1-Deamino-8-d-arginine vasopressin: a new pharmacological approach to the management of haemophilia and von Willebrands\u2019 diseases. Lancet (London, England). 1977;1:869\u201372.","journal-title":"Lancet (London, England)"},{"key":"899_CR25","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1055\/s-0038-1646050","volume":"58","author":"S Lethagen","year":"1987","unstructured":"Lethagen S, Harris AS, Sjorin E, Nilsson IM. Intranasal and intravenous administration of desmopressin: effect on F VIII\/vWF, pharmacokinetics and reproducibility. Thromb Haemost. 1987;58:1033\u20136.","journal-title":"Thromb Haemost"},{"key":"899_CR26","doi-asserted-by":"publisher","first-page":"e649","DOI":"10.1016\/j.wneu.2018.05.064","volume":"116","author":"PM Foreman","year":"2018","unstructured":"Foreman PM, Ilyas A, Mooney J, Schmalz PGR, Walters BC, Griessenauer CJ. Antiplatelet medication reversal strategies in operative intracranial hemorrhage: a survey of practicing neurosurgeons. World Neurosurg. 2018;116:e649\u201354.","journal-title":"World Neurosurg"},{"key":"899_CR27","doi-asserted-by":"publisher","first-page":"2605","DOI":"10.1016\/S0140-6736(16)30392-0","volume":"387","author":"MI Baharoglu","year":"2016","unstructured":"Baharoglu MI, Cordonnier C, Al-Shahi Salman R, et al. Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial. Lancet (London, England). 2016;387:2605\u201313.","journal-title":"Lancet (London, England)"},{"issue":"544\u20139","key":"899_CR28","first-page":"e1","volume":"208","author":"CE Collins","year":"2014","unstructured":"Collins CE, Witkowski ER, Flahive JM, Anderson FA Jr, Santry HP. Effect of preinjury warfarin use on outcomes after head trauma in Medicare beneficiaries. Am J Surg. 2014;208(544\u20139):e1.","journal-title":"Am J Surg"},{"key":"899_CR29","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1001\/archsurg.2010.313","volume":"146","author":"LA Dossett","year":"2011","unstructured":"Dossett LA, Riesel JN, Griffin MR, Cotton BA. Prevalence and implications of preinjury warfarin use: an analysis of the National Trauma Databank. Arch Surg (Chicago, Ill: 1960). 2011;146:565\u201370.","journal-title":"Arch Surg (Chicago, Ill: 1960)"},{"key":"899_CR30","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1097\/TA.0b013e31812e519b","volume":"63","author":"FM Pieracci","year":"2007","unstructured":"Pieracci FM, Eachempati SR, Shou J, Hydo LJ, Barie PS. Use of long-term anticoagulation is associated with traumatic intracranial hemorrhage and subsequent mortality in elderly patients hospitalized after falls: analysis of the New York State Administrative Database. J Trauma. 2007;63:519\u201324.","journal-title":"J Trauma"},{"key":"899_CR31","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1097\/CCM.0b013e31826ab38b","volume":"41","author":"JN Harr","year":"2013","unstructured":"Harr JN, Moore EE, Johnson J, et al. Antiplatelet therapy is associated with decreased transfusion-associated risk of lung dysfunction, multiple organ failure, and mortality in trauma patients. Crit Care Med. 2013;41:399\u2013404.","journal-title":"Crit Care Med"}],"container-title":["Neurocritical Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12028-019-00899-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12028-019-00899-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12028-019-00899-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T01:13:27Z","timestamp":1609463607000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12028-019-00899-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,2]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["899"],"URL":"https:\/\/doi.org\/10.1007\/s12028-019-00899-x","relation":{},"ISSN":["1541-6933","1556-0961"],"issn-type":[{"value":"1541-6933","type":"print"},{"value":"1556-0961","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,2]]},"assertion":[{"value":"2 January 2020","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Dr. Barletta is a consultant for Wolters Kluwer. Dr. Abdul-Rahman has no conflicts of interest to report. Dr. Hall has no conflicts of interest to report. Dr. Mangram has no conflicts of interest to report. Dr. Dzandu has no conflicts of interest to report. Dr. Frontera was an author on the manuscript: \u201cGuidelines for reversal of antithrombotics in intracranial hemorrhage. A statement for healthcare professionals from the Neurocritical Care Society and Society of Critical Care Medicine\u201d published in Neurocrit Care 2016;24:6-46. Dr. Zach has no conflicts of interest to report.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study has been approved by the institutional review board and performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards. For this type of study, formal consent is not required.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval\/Informed consent"}}]}}