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Choi has received consultant fees from Grace Pharmaceuticals. The remaining authors have disclosed that they do not have any potential conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Institutional review boards (IRBs) at participating institutions reviewed and approved this study. IRB approvals were as follows: UTHealth-MHH (HSC-MS-12-0637) and UMSOM (HP-00074174). All methods were performed in accordance with the Declaration of Helsinki. Prior to enrollment, informed consent was obtained from all patients or their legal guardians.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}