{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T18:06:52Z","timestamp":1784052412903,"version":"3.55.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Odense University Hospital"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurocrit Care"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Chronic hydrocephalus after aneurysmal subarachnoid hemorrhage is a common condition that can require shunting of cerebrospinal fluid to the peritoneal cavity [ventriculoperitoneal shunting (VPS)]. Several predictive scoring systems have been developed to estimate the risk of requiring VPS, most recently the Mayo age, grade, EVD (MAGE) score and the SAH-VP score. The aim of this study was to identify predictors of ventriculoperitoneal shunt dependency and to develop a new predictive score to compare with the MAGE and SAH-VP scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A retrospective single-center cohort study of 220 patients admitted with computed tomography (CT)-verified aneurysmal subarachnoid hemorrhage (aSAH), of whom 114 required extraventricular drainage, between 1 September 2018 and 21 January 2025, was conducted. They were categorized into two groups: those requiring VPS (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200962) and those who did not (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200952). Univariate and multivariate analyses (least absolute shrinkage and selection operator logistic regression combined with the extended Bayesian information criterion for the latter) were performed. Statistically significant variables were entered into a generalized linear model. A clinical risk score was developed by scaling and rounding the bootstrapped regression coefficients relative to the smallest significant effect.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Least absolute shrinkage and selection operator (LASSO) regression identified seven predictors: intensive care unit (ICU) stay \u226510 days (OR 10.85), World Federation of Neurological Surgeons (WFNS) score of 5 (OR 1.35), EVD duration\u226514 days (OR 1.73), two or more failed weaning attempts (OR 5.38), clamp failure (OR 2.99), cerebrospinal fuid (CSF) output&gt;200 mL in the frst 3 days (OR 3.67), and failed closure after weaning (OR 4.42). The final model, named the Islamagi\u010d Shunt score (IS-score) demonstrated a bootstrapped area under the receiver operating characteristic curve (AUC) of 0.914 (95% CI 0.87\u20130.95). In comparison, the SAH-VP yielded an AUC of 0.736 (95% CI 0.66\u20130.80) and the MAGE score an AUC of 0.791 (95% CI 0.73\u20130.85).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The IS-score demonstrated superior predictive performance for VPS following aSAH compared with the MAGE and SAH-VP scores, but further external validation is needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s12028-026-02461-y","type":"journal-article","created":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T17:14:00Z","timestamp":1772817240000},"page":"237-246","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Development of the IS-Score: A Novel Predictive Model for Shunt Requirement Following Aneurysmal Subarachnoid Hemorrhage"],"prefix":"10.1007","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3239-5951","authenticated-orcid":false,"given":"Lejla","family":"Islamagi\u010d","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilies","family":"Djebbara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Troels Halfeld","family":"Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sune","family":"Munthe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,6]]},"reference":[{"key":"2461_CR1","doi-asserted-by":"publisher","first-page":"559 EP","DOI":"10.1007\/s00701-017-3081-8","volume":"159","author":"V Benes","year":"2017","unstructured":"Benes V, Jurak L, Brabec R, Nechanicka N, Sercl M, Endrych L, et\u00a0al. 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Rather, permission from the Regional Council (Regionsr\u00e5det) was obtained.","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}}]}}